LOCUS       c00041_gnlPro..        16551 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HFDJOECK_41.
ACCESSION   c00041_gnlPro..
VERSION     c00041_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 23:47:05
            Original ID  :: gnl|Prokka|HFDJOECK_41
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16551
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16551
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[9844:13402](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(9845..13402)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16551
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16551
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             186..1412
                     /locus_tag="ctg41_1"
                     /transl_table=11
                     /translation="MFFFLIVPLFLALFYKPIAYLCGRFLNNKSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGFQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGRRVGRWKRYTIDG
                     KLEKEWDEN"
     CDS             1745..4498
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 64.3; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_2"
                     /sec_met_domain="Peripla_BP_1 (E-value: 7.4e-21, bitscore:
                     64.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFGLIGMTACRQDTPRFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGKIAVRLSSLSKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQSCEAV
                     AAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKPSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
     CDS             4526..4858
                     /locus_tag="ctg41_3"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(4821..6107)
                     /locus_tag="ctg41_4"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFIRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFMAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVTMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQTLGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTTTDKILFWCCFVLLCIVPIDIFVPVPIRDLITKTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             6580..7806
                     /locus_tag="ctg41_5"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQICTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMCERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             7803..8633
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg41_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.9e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIEAAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             8661..9521
                     /locus_tag="ctg41_7"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVIPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(9532..9720)
                     /locus_tag="ctg41_8"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(9845..13402)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg41_9"
                     /sec_met_domain="PFOR_II (E-value: 5e-19, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.1e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.8e-32, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.5e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.6e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             complement(13436..14641)
                     /locus_tag="ctg41_10"
                     /transl_table=11
                     /translation="LPAEKQRNEMESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGI
                     KGTRGVGKTTFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLID
                     QVFKHPEWSKELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFL
                     NLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENL
                     LKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMN
                     YIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLW
                     KDHKVHKGDKNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGF
                     LY"
     CDS             14821..15975
                     /locus_tag="ctg41_11"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDWKFSPWGWDPALRKRLMTLGAGQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
ORIGIN
        1 ttgtgatatt taatactgca aatgtaaatg tgtcaaaagc aactaaactc tcctccttcc
       61 tgaaggaggg gaatttagtt gcttttgaca catcttcttt tctgtttctt atttcagtaa
      121 atgtccccct tccctgtgtt ttgatttact acttaatctg ttaattatta gaatgataat
      181 aacagatgtt cttttttcta attgtccccc tctttcttgc cttgttttat aagccgattg
      241 cctatctttg cggcaggttt ttaaataata aatcaaaaag agaaaactac tttatgaaac
      301 acatttcgaa cttcctcaga tcaaaaagct ggaacgtatt tttgttttta tatcttgctc
      361 ttcctttgtt tgcgcaaaag gaatataaga tcgatcaggt atctgttgtt aatgtaggcg
      421 atggcagact gttgtttcag gaactgaaaa cggaaaaagc attgaatggc gaacatcgca
      481 tcatagatgg ttatcattcc gcctatgtgc tggcatcttt taaagatggt ttttatgatg
      541 gcggatacaa agaatatgtg gacaatatat taataacgga aggaagttat aaagaagggc
      601 ggaaggatgg cctcttcaag attaactcca agtttgacgg taagctgaaa gaagaaaagt
      661 cctataagga aggtaagctg gacggtacga gcaaaagtta ctttactacc ggaaaagtgg
      721 aaagtgaaag aaacttccgg atggggaaag agcacgggaa gcaactgtcg tacgaatctg
      781 acggtacttt gcggaaagag cataattaca aggacgggaa gcaggtaggc aaacagtata
      841 cttttctgaa aggtacatat gatttgtatg agaccgttta tttcaatgaa gaaggttttc
      901 aggacggtga atattcgtcc gtgtttacgt ttggctcgcc acgtatactg ggtagttata
      961 agaatggaaa gaagaatggt cgttggacta cttttgctga aagcggagat acgctgatga
     1021 ttgaaaccta tctggatgga aaagaagatg gactccatgt ctcatttgcc aacggaagtg
     1081 gggtaaggca gaaagaatat tatatgaaga acgatcgtaa agacggttta taccgtgaat
     1141 ataatttgga aaatggtgaa ttgagatatg aagctaccta tcaggccggc agattgcatg
     1201 gcaaggaacg acggctgata gtgagcaacc gctttgatta ttgggaaact tctacctatg
     1261 tgaacggaag gcagaacgga ccgttcgaag ctcgttatgt aaagaatgac cagcttcgtg
     1321 aatgtgggga atataagaat ggtcgtcgtg taggacgatg gaaacgctac actattgatg
     1381 gtaaactgga aaaggaatgg gatgaaaact aatcggtaga tgaaaggtca gggcataaaa
     1441 aaaggagcaa cgccttgctc caacctttgt taaccttaaa tctaatacta tgaaaaacac
     1501 agtacaaaga tacggacttc tgtgaaatct gcaaattatc caagtaaaac gctatgtttt
     1561 ataacattga ttaagtgttt gttttacgct ttatactttt gttaatactt tccgatggtc
     1621 tgaaagagga ctgctttcct tctttttaga ataataaata gctgaagtta gagaacttta
     1681 cagtattatt tcttattttt gttcttaatt ggattacaga aagaactatg aaatgatgag
     1741 atggatgaag acgatgagat atctgaagtg gatgctggtg ctgtttggtt taatcgggat
     1801 gacggcttgc cggcaggata caccccgttt tcgtattggg gtggctcaat gcagcgatga
     1861 ttcatggcga cataagatga atgatgagat tcttcgggaa gcgatgtttt ataatggtgt
     1921 ttcggtggaa atccgttcgg caggggatga taacagtaag caggcggaag atgtccatta
     1981 ttttatggac gaaggagtcg atctgctgat tatttccgct aacgaagctg ctcctatgac
     2041 tccgattgta gaagaagctt atcagaaagg catccccgtt attcttgtag accggaagat
     2101 tctttcggat aaatatactg cctatatcgg agccgataat tatgaaatcg gtcgttcggt
     2161 aggaaactat attgcctcca gtctaaaagg gaagggaaat atagtagaac tgacaggatt
     2221 gagcggttcg actcctgcaa tggaacggca tcagggattt atggctgcca tcagtaaatt
     2281 cccggatata aagctgattg ataaagcgga tgctgcgtgg gaacgtggtc cggcagagat
     2341 agaaatggat agtatgcttc ggaggcatcc taagattgat gctgtgtatg cccataatga
     2401 ccgtatcgct ccgggtgcct atcaggcagc aaagatggca gggcgggaga aggaaatgat
     2461 ttttgtcggc atagatgcct tgccgggtaa gggaaacgga ctggaactgg tactggacag
     2521 tgtgctggat gccaccttta tctatccgac caatggcgat aaggtactgc aactggctat
     2581 ggacattctg gagaagaaac cctatcccaa agaaacggtg atgaataccg ctgttgtgga
     2641 ccgtaccaac gcacacgtca tgcagttgca gaccacacac atttccgaac tcgataaaaa
     2701 gattgaaacg ctcaacggac gtatcggtgg atacctctct caggtagcta cacaacaggt
     2761 agttttatac ggcagtctga ttatcctttt attggtagcc ggcttattat tggtcgttta
     2821 taaatcactc cgctctaaga atcgcttgaa taaagagctt tttaagcaga agcagcaatt
     2881 ggaagagcag cgtgacaaac tggaagaaca gcgtgaccaa ttgatacaac tttctcatca
     2941 actggaagaa gctactcatg ccaagctggt attcttcacc aatatttctc acgacttccg
     3001 tactccgttg acattggttg ccgacccagt agaacattta ttggcggaca agacattgag
     3061 tggagatcag caccggatgc tcatgctgat tcagcgaaat gtgaacattc ttctgcgtct
     3121 ggtcaatcag attctggatt tccgtaaata tgaaaacggc aagatggaat atactccggt
     3181 tacggtggat gtcctttctt ctttcgaagg atggaatgag tcttttcagg cggcagcccg
     3241 taagaagcat atccattttt cttttgatag tatgccggat acggattatc atacactggc
     3301 agacatggag aagctggaac gtatttattt caatcttctg tccaatgcct ttaagtttac
     3361 accggaaaac gggaaaatag ccgtccgtct gtcttccctt agtaaagagg acaagcgatg
     3421 gatacgtttc acggtggcaa ataccggttc tatgatttct gccgaacata ttcgcaatgt
     3481 attcgaccgt ttctataaga tcgatatgca ccataccggt tcgggaatcg gactggcatt
     3541 ggtaaaagcc ttcgtagaaa tgcacggtgg tatgatctcc gtagagagcg atgagaaaca
     3601 gggcacggtc tttaccgttg aactgcctgt acagtcttgt gaggctgttg ctgccgagcc
     3661 ggataccacc cttgtttctg cggattcccg tacaacagat gttctattgg cggaagagga
     3721 agaactggaa aaaggatatg actcttccaa accgtccgta ctgattattg atgataatga
     3781 ggatatccgt tcgtatgtcc atacgctgtt gcatacagac tatacggtga ttgaagcggc
     3841 agacggctcc gaaggaatcc gtaaggctat gaagtatgtt ccggacctga tcatttctga
     3901 tgtgatgatg ccgggcattg atggcattga atgttgccgc cggctgaaaa gtgagttaca
     3961 gacctgtcat attccggtta ttctgctgac agcgtgttca ctggacgaac agcgtattca
     4021 gggatatgac ggtggtgcgg attcttatat ttcaaagccg ttcagttcac agctgttgct
     4081 ggcacgtgtc cgcaatctga tcgattctca ccgtcgtctg aaacagttct ttggtgacgg
     4141 gcagacattg gcaaaagaag atgtctgcga tatggacaag gattttgtag aaagattcaa
     4201 gtcattgatt gaagagaaaa tgggagactc cggtttgaat gtggaggact tgggcaaaga
     4261 catgggacta agccgtgtgc agctttaccg caagattaaa tcattgacta actactctcc
     4321 gaatgaattg ctccgtatcg cccgtttgaa gaaggcagct tctttgcttg cttcttcgga
     4381 catgaccgta gcggagattg gttatgaagt cggtttcagt tcaccttctt atttcgccaa
     4441 gtgctataaa gagcagtttg gagagagccc gacagatttc ctgaaaagga aaggatgatt
     4501 tcattgtgat cgtaaagagg gatatatgaa agattataaa gtagataaag agagcttttc
     4561 tgaatccttt cggaaggaag tgtacgaagt cgtatcccag atacctgtgg gaaaagtatc
     4621 tacttatgga ggtattgctt tgctgttggg ggcaccccaa tgctcgcgga tggtgggacg
     4681 tgcattgaaa gaagtgccgg atgaattatc cattccctgc catagagttg taaattccac
     4741 cggaaggctg gtgcccggtt gggtggaaca aaaacaactc ttgctggcag aagaagtttc
     4801 tttcaaagct aacggatgcg ttaatctgaa agaacatttg tggcacgtgg atgaatgaag
     4861 gatgcaagga aggtaagcca tatcatccgt atccatacaa taaagaaaac ccatacatga
     4921 agccataagg tcttggtaat gagatctctg atgggtacag ggacgaatat gtcgatagga
     4981 acgatacata acagcacaaa acagcaccaa aatagaatct tgtctgttgt ggtacgtgtt
     5041 ggcctgctcc aataccagag catgaaacct gccaatgcga taatataggt atgtttttcg
     5101 gcggagtcac tcagtaatac tacccagccc atgagaatgc ccaaagtctg ggcacggaag
     5161 gcaaaagacg accatttgcg gaaattcccc aaaaagagca gagtcagcaa gccgagcatt
     5221 cctatctgaa gtgcacggaa gtgtggtaat gtccatgctg caatggggcg ggcatagaaa
     5281 aatgaatcat aagctccggc ggactgatga acagcaagac tatggcacca ttcttcataa
     5341 taggggagca aatctgcagg agctattttg attaacggta atgcaagcaa tacaatgccc
     5401 attgtaacgg catagccaaa gttacgccat acgtgaggat agcacagcaa caatgccagt
     5461 tcgaaaattc catatacttt ggtacatccc gaaatcatga ttaacagaac agccagaaat
     5521 ccacggtctt tttccaataa cgtataggcg aataagaata aataggctac cgttatgtta
     5581 tactgaaatg aaagtaaact ttgtcctaaa atcagtaaca gaaaaaggaa catacggcat
     5641 ttctgctgct gggtgaattg ttggggcagc gtgaagatcg ccataaagaa cagcgaataa
     5701 ttgaatagat tccacgcgaa aggtcccagc catgcaggca gatacgcaaa cggagcgaac
     5761 aataccgtga aaactggaga ataaaggaag tagcgtccgt gagcttctac aaattcagtt
     5821 gtgtatgggc tgatgccttg ccagaagaat tgagtagcgt ccgagaagac cataaagttt
     5881 tgatgccgtc ctcgtataaa ttcgagcaga gtcactataa aagcgagcag gaaacctatc
     5941 atgtagagat tccgccggct atagaaaaac ggcattttgg ggttcttttt actaaggaac
     6001 tgtacttggc ttttgtcgtc tagtgtggca gtacctgttt gtttttcttt tgttgtgtaa
     6061 tgacaattat ccttccccag gaaaattgta atagccctgt tgaacatata aatctagttt
     6121 agttattgac gccaaatata cggtgtttaa gtgaaatatt caaacttatt ttatatttat
     6181 ctgccggttt gttctatttt gctgagtgat aggggaatat tacccggaaa ctttccatat
     6241 cattacaaat aaagccctct gtatgccccg gattttgaat ataatttgta tgtttaatcc
     6301 gttttttgta tctttgtgcc agcaagatac tggaacaggc tgtttttata cataaaaatg
     6361 ctattttttg ctattcgttg aaaggattat cttatcaaat tcgattcctt ttttaattac
     6421 tcagtctgtc aataatcatt ttattaatta tttcgggatt cattgttatt tgtcccgtat
     6481 ttaaatcaga actttatacg atataaagaa agattcctgt tatcgtttgt tcttgtcttg
     6541 ctgtgtatat tattttaata acctaaacca ttttattgta tgagtaaaat agaaattaaa
     6601 gatctctatc tggtttttgg caatgagaag cagaaggctt tgaagatgtt gaaagaaggt
     6661 aaaacaaaaa gtgaaatatt gaaagcgacc ggatgtacag ttgcggtgaa agatgcgaat
     6721 ctttccatta atgaaggcga aatattcgtc attatggggc tgtccggtag tggaaagtcc
     6781 actttactcc gctgcatcaa ccgtttgata cgccctactt ccggagaagt gattatcaat
     6841 ggaacagaca tagccaaagt gtcggataaa gaactgttgc agattcgccg gaaagaactg
     6901 gctatggtct ttcagaactt cggtctgctt cctcaccgtt ctgtcttgca taatatagct
     6961 ttcgggctcg aactacaggg agtaaaaaag ggagaacggg agcagaaagc gatggaaagt
     7021 atgcaactgg tggggctgaa aggctacgag aatcagatgg taagtgaact gtcgggtggg
     7081 atgcagcagc gtgtcgggct ggcgcgggct ttggccaata atcccgaagt cctgttgatg
     7141 gatgaggcct tctcggcact cgatcctttg atccgtgtgc agatgcagga tgaactgctg
     7201 actttgcagt cgaagatgaa aaaaacgatt gtctttatta ctcacgacct gagtgaagcg
     7261 attaaattgg gtgaccggat tgctatcatg aaggatggag aaattgtaca aatctgtaca
     7321 tcggaagaaa tcctgaccga acctgccaac gcttatgtag aacgatttgt ggagaatgta
     7381 gatcgaagta agattataac agcttcctct gttatggtag ataaacccat agtggcacgt
     7441 ttgaagaaag aaggcccgga ggtgctgatc cgtaagatgt gcgaacggaa tctgaccgtt
     7501 cttccggtag tcgattccaa taatctgtta gtaggagagg tgcggttgaa tgacttgctg
     7561 aaactacgaa aagagcaaat ccgctccatc gagtccgtag taaggcatga agttcattca
     7621 gtgctggggg atacggtgct ggaagatatt cttccgttga tgacaaaaac gaactcgcca
     7681 atctgggtcg taaatgagaa tcgggagttt gaaggcgtag tgccactttc ctcattgatc
     7741 atcgaagtaa cgggaaaaga taaagaagaa attaatgaaa tcattcaaaa cgcaatagaa
     7801 ttatgataaa tatcggacaa tatatagagg ctgccattaa ttggctcaca gaacattttg
     7861 cttccttttt tgatgctctc agcatgggga tcggaggatt catagacggt tttcagcatg
     7921 tactgtttgg aatacctttt tatatcacaa ttgcagtgct ggctgcgctc gcctggttta
     7981 agtcgggtaa ggggacagcc gtatttaccc tcttgggttt attgcttatt tacggcatgg
     8041 gcttttggga agaaacgatg cagacattgg cgttagtact ttcttccact tgtctggcat
     8101 tgcttttagg cgttccgctg ggaatctgga ctgccaacag tgatcgttgt aacaagataa
     8161 tgcgccctgt cctcgacttt atgcagacaa tgcctgcctt tgtctatctg attcctgccg
     8221 ttctattctt cggattggga actgtgccgg gagcttttgc caccatcatc tttgcaatgc
     8281 ctcctgtggt tcgtctgacc ggtctgggca ttcgtcaggt tcctaaaaac gtagtagaag
     8341 cctcccgctc ttttggagct actccctggc agcttcttta taaggtgcaa ttgcctttgg
     8401 cgttgcctac tattctgacg ggaatcaacc agacgatcat gatgtcactt tcgatggtag
     8461 tgattgctgc catgatttct gccggaggat tgggagaaat cgtgctgaaa ggtatcaccc
     8521 aaatgaaaat cggactcgga tttgaaggcg gtatcgcagt cgtgatattg gcgatcgtgc
     8581 tggaccgcat cactcagggt atggcagata acagaaaaag taaaaagaaa taagaatcac
     8641 accaaagaaa ggaataatca atgaataaga taaaaatgat tgcggcaatg tttattgccg
     8701 gcatactctt aaccttcgtt tcctgcggag acaacggaaa gagtaagaag ataagtatcg
     8761 cttatgccaa ctggtcggaa ggtattgcaa tgacaaacct tgccaaagcg atttttgaag
     8821 atcaggggta cgatgtaaag ttgctgaatg ccgaccttgc acctatattt acctctatct
     8881 cccgtaagaa agcagacgta tttatggatg tctggatgcc tgtcactatg gaagattata
     8941 tgaaacaata cggggataaa ctcgaagtta tcggggatat ttatgatggt gcccgtatcg
     9001 ggctggtgat tccggattac gttacgatca actcaatcga agaactgaac gcggaaaagg
     9061 aacgtttctc cggtcagatt gtcggtattg atgccggagc cggtattatg aaagctaccg
     9121 atcaggccat caaagactat ggattggatt ataaactgat gacttcgagc ggacctgcca
     9181 tgactgcttc cctaaagaaa gcgattgata agaaagactg gattgtcgtg acgggatgga
     9241 cgcctcactg gatgttcgac cgtttcaagc tgaaagttct tcaggacccg aagctgatat
     9301 atggaaatac ggaatccatt cataccatag catggaaagg ttttagcgag aaagaccctt
     9361 ttgctgccga acttttgggc aacattcgtc tgacagatgc ggaaatcagc tctttaatga
     9421 ctgctctgga agaggcgcag acaacggaaa gacaggctgc ccgtcaatgg atggaagaac
     9481 atcaggaact ggtaaacagt tggattcctg agaaagattg atatgcaaac actacttcaa
     9541 ccatcctgcc attctttctt taccatagaa gtagtagaaa agtagtccca gccagctggt
     9601 aagaacgatt aatacaatcg ctataagtct tttctctaca gccgcattta tattccaaat
     9661 ctctatggca gctctgaaag tcagtatcaa accgataatc caaataacaa atccgatcat
     9721 atctttagag ttttaatgaa tatcttcgtg agaagtaatc gttacttcta agatataaac
     9781 aaaaaaggca ggaatctgtt tccaggattc ctgcctttta ttatgtataa agtatttcta
     9841 cttattattc agctgtatca gctccccagt tttctctggc aagacgtttg tagctgttgt
     9901 aacgccattt agcgttttct tcagcagctt taaacagttc ttcagcttca gcaggatatt
     9961 gtttcattac agaagcgtaa cgaacttcac ccttcaagaa accttggaag tcttcccagt
    10021 taggttcttt gctatccagt tggaacggat tcttgccttc ttcttccaaa gcagggttgt
    10081 aacgccacaa gtgccagtaa ccgcacttaa cagccttttc ttcttcttcc tggctcttac
    10141 ccataccggc tttcagaccg tggttgatac atggagcgta agcgatgatc agtgatggtc
    10201 ccggatatgc ttcagcttca cggatagctt tcagagtctg agcctggtca gcacccatag
    10261 caatctgagc aacatataca taaccgtaag tagtagccat cagaccgagg tctttcttac
    10321 gtacacgctt acctgcagca gcaaacttag cgatagcgcc taccggagta gctttagaag
    10381 actgaccacc tgtgttagag taaacctcag tatccaatac aaggatgtta acgtccttac
    10441 cggaagcgat tacatggtca agaccaccgt aaccgatatc ataagaagca ccgtcaccac
    10501 cgatgatcca ttggctgcgt ttaacaagat attgttgcag atcagcgatt tgcttgcagt
    10561 ggttgcattt atctttagca gcttctacca tcggaatgat cttttcggcc agttccttag
    10621 tcttttctgc atccagcata ttgttgatcc attcagcaaa tacttctttg tattcagccg
    10681 ggcagcaatc agaagcgata gcttcgttca ttactttcac cagacgggca cgcatctttt
    10741 cgttagccag ttccataccc agaccaaatt cacagaagtc ttcgaacaag gagttagccc
    10801 atgcaggacc gtgacccttt tcgttcatag tgtacggagt agaaggaact gaaccggagt
    10861 agatagaaga acatcctgta gcgttagcaa ccatttcacg gtcaccgaac aactgagaaa
    10921 tcagtttcac gtacggagtt tcaccacaac cggagcaagc gcctgagaac tcaaacaacg
    10981 gagttgcgaa ctgagagttc ttcacgttag ccttgatgtc taccaggtgt tgtttgctct
    11041 tcacgttttc agcgcagtaa gtccagttat cagcttcggc caactggctt tcaaggtgtt
    11101 tcatggtcaa tgccttgcca cccttcttcg gattacccgg acagatgtcg gcacagttac
    11161 cgcaacccag acagtcgaga acgtctacct gaatacggaa tgtcatacca tcgaatgctt
    11221 tacctacagc tttcagttgc tcgaacttag cacccttctg ctcttcagca tcgagtacga
    11281 acggacggat agaagcgtga ggacaaacgt aagcacactt gttacactga atacagtttt
    11341 cagcattcca ttcgggaacg aatgcagcta caccacgttt ttcgtatttg gaagtacctt
    11401 gataccaagt accgtcttcg atacccttga atgcagatac cggcagcaag tcaccgtcct
    11461 gtgcattgat cggacgaact acttcgttga tgaaagcagg atcattgttt tctgcttttg
    11521 catcatccgg caggttagcc caagcaggat cgacagtcag agtcttgtat tcaccaccgc
    11581 ggtctacagc agcgtagttc ttgttaacaa cgtcttcacc cttcttgccg taagacttaa
    11641 cgatgaattt cttcatctgt tcaacagctt gatctacagg gattacgcct gtgatacgga
    11701 agaatgcaga ctgaaggatt gtattggtac ggttgcccaa accaatttcc attgcaatct
    11761 gagttgcgtt gatatagtat acagagatgt tgttctgtgc aaagtatttc ttcaccttgt
    11821 taggcaggtt cttagccagt tcttcgcctt cccagatggt attcagcaag aaagaaccgt
    11881 tcttacgcaa accacgtgtt acgtcgtaca tgtgcaggta agcctgaacg tgacaagcaa
    11941 cgaagttcgg agtatttacc aagtaagtag aacggatcgg agtatcaccg aaacgcaagt
    12001 gagaacaagt gaaaccaccc gacttcttgg agtcgtaaga gaagtaagcc tgacagtgtt
    12061 tgtcggtgtt gtcaccgata atcttaacag agttcttgtt ggcacctact gtgccgtcag
    12121 cacccagacc gtagaattta gcttcgaaca taccttcacc gcccagagcg atttcttctt
    12181 tctgaggaag agaagtgaac gtaacgtcgt ctacgatacc gatagtgaag tggttcttcg
    12241 gcattggcat agccaagttt tcgaatacag agatgatctg tgccggagtg gtatcttttg
    12301 aacccagacc gtagcgaccg ccaacgataa caggagcatt ttctgcgcca tagaagcagt
    12361 ctttaacgtc aaggtaaaga ggttcgccgt tagcacccgg ttcttttgta cggtcaagca
    12421 ctgcgatgct ctttgcagtc ttgggtacag cagccaggaa gtgtttagca gagaacggac
    12481 gatacaagtg tacggcaacc atacctactt tttcgccgtt tgctaccaag tggtcgatag
    12541 cttcgcgggc agcttcagtt acagaaccca ttgcgataat tacgcgttct gcatcttctg
    12601 caccgtagta atcgaacaaa ccgtatttgc ggcctgtgat cttggaaatt tcgttcatgt
    12661 attcttctac gatagcagga actgcttcat agtagttatt gcatgattca cgatgttgga
    12721 agaagtggtc ggggttttca gccataccac gggcaaccgg cttcatcgga ttcagtgcac
    12781 gggcacggaa ttcagccaaa gcttcctggt cgatcagcgg agcgaggtcg tcgttttcca
    12841 acatttcgat cttctggatt tcgtgagaag tacggaaacc atcgaagaag ttcatgaacg
    12901 gaacgcgtga tttgatagta gccagatgag caacacctgc caaatccata acttcctgta
    12961 cagaaccttc tgccaacata gcgaagccgg tttgacgagc tgacattacg tcctgatggt
    13021 caccgaagat acacaatgcg tgagaagcca gtgtacgagc agaaacgtgg aatacacaag
    13081 gcaagaattc accggcaatc ttgtacatgt tagggatcat caaaagaaga ccctgagaag
    13141 cagtgtaagt agtagtcaat gcaccagcct gaagagaacc gtgaactgca ccggcagcac
    13201 caccttcaga ttgcatttcc tgtaccaata ctgtttcgcc gaagatgttc ttacgtcctg
    13261 cggcagccca ttcgtctacg tactcagcca tagtcgaaga aggagtgatg gggtagatag
    13321 ctgctacttc agagaacata tacgagatat gtgctgcagc ttggttacca tcacatgtga
    13381 tgaatttctt ctgtttagtc ataactaaat taaatattta agtaaataaa tctttttagt
    13441 ataagaatcc gaacatccaa agaggtattt ggttgccgcg gcctatctcg gccttttgca
    13501 acgcatacgt cacgtccggg ttattcttta tttttgtacc ttccgcacaa attttgaacg
    13561 gcatcacttc gtctaccatg aaagagacgt ttttatctcc tttatgtacc ttatggtctt
    13621 tccataaagt gttaacgaag aacgtgtcga gtacatcctg ttcttccact ttcaccggat
    13681 aaatggagta catcaggtta gagttgtgca tcataatctt tgacggtttc tttgggaatt
    13741 cttctccttt cgggtaaacc agattaatca gacgcgcgtc tgccagatac ttgatatagt
    13801 tcattaccgt agcgcgggat gtctgtacgt cacttgccag ttggctcacg ttcggagctt
    13861 tcggtccgtc cacagccaac aaatatagta atttttttat ctttgaaaga tatttcagct
    13921 caatttgttt gatcagcaag atatccactt ctaccatcat gttcattgtt ttcagcagat
    13981 tctccgagaa attacgtttt tcaaggaaga aagggtagaa accatgatgc aggtaatcct
    14041 gaaaataatc cagcggtcgt actttggaaa gtactccttt ggctatctgt tcatgtgtac
    14101 tgaggatttc ttcgaggctg tatgcccgga atttcattcc tgtctgcagg ttcagaaatt
    14161 cacggaaaga gaatccgcgc aggttataac ttttcgcaat gtcacgcaat tcgaggtttt
    14221 cctctttgag tcgcatgacg gaagaaccgg tgaagacaat cttcaggctg gggaaacggt
    14281 catagcacat tcgtagctct ttgctccatt cgggatgttt gaacacctgg tcgatcagca
    14341 gtacttttcc gccacgtttc tgaaactcgt tggcgaagtc aacaaggctg tgaccggaga
    14401 aataaaagtt gttcatattg atgaacagac aggaacggtc ggtgccgaat ttctctttgg
    14461 cgtactgcag gaggaaagtg gtttttccta cgccacgtgt ccctttgata ccaatcagac
    14521 ggtcactcca gtcgatctcg tccataagat cgcggcgaac gggggcattg gtgtgctcaa
    14581 cgaggtaggc gtgtgtgcga tagaatgatt ccatttcgtt tctttgtttt tcggctggca
    14641 aatatagtgc tttttttagg atttgcaaag tagagatagc aaaaatgtgc tttaatttat
    14701 aagtttctct ttattgtgta agttcctgat tatttcctgt atatatttgc agaataatgt
    14761 gttgaatcca tctttgacat gacgaaaaga cctgtttata tattcaatcc ggagcatgat
    14821 atggcgttgg caagcggtga gacgaactat atggcgccgg cttccgcccg acagatggcg
    14881 agtgacctgg cgttgcttcc tatgtggtat gccgaagcgg gaagtgcggt gcttgcaccg
    14941 tctgcttata atgcggactt cctgaaaaca aagagtgaac ttttgggcat ggatgtggcc
    15001 ttgttgacgg aaccggaagt ggctgacggt aaagactgga agttctctcc gtggggttgg
    15061 gaccctgctt tgcggaagcg tttgatgaca ttgggggcag gtcagacgga gctgccttct
    15121 gcggattata tgaatattct gagagagcat tcgcatcgtc tgcaggcggt aaagttgttg
    15181 cctgggttgc ggttgaatga atacttctgt ggagaatctt tttatttgag tactttggcg
    15241 gagtgcagtg cgttcgtcga agggcgggaa gcgtgcttgt taaaagctcc gctttccgga
    15301 agcgggaaag gattgaattg gtgtaaaggc atatttacta cttttatttc cggttggtgt
    15361 gcccgtgtcg ctgcttctca gggtggggtg gtaggcgaac ctatatataa taaggtggaa
    15421 gatttcgcta tggagtttta tgctgacggg agaggaaggg ttgtttttgc cggatattcg
    15481 gtcttccaca cgggtgggag tgggatgtat gcagggaatg acttgctgtc tgacgagaag
    15541 attctgcaga aactatcggc ttatgtgcca caagaagaat ttatcaggct gcggactcgt
    15601 ttggaagaag aattgtcagc tttgttcggt ggcttttatc atggatactt gggagtggat
    15661 atgatgattt gtcattttcc ggatgaagcg cctgtttacc ggattcatcc ttgtgtcgaa
    15721 attaatctgc gaatgaatat gggggtggtg gcatggctct tgacggatcg ttatttggct
    15781 gcggatgcgg aaggagtttt tcggattgat tattatcctt tagccggtca ggctttggag
    15841 gaacatcggc agatgtcggc ttcgttccct ttgtccgtag agaataatcg ggtgtgtgcc
    15901 ggatatttgc cgttagtacc ggtgacgcct caaagccggt atcgtgcgtt tcttttgctt
    15961 actctccccc agtgaaaaag atagtgcttt tgctctcatg ctctaacagt tcgtctgtat
    16021 ccctttattc atcgatgttt tagctgttag agatccagtg gtagcagagt gagagcaagg
    16081 acttgctctc actctgcatc gtcctgataa atactgtttt tactgtgtta ttctttgatt
    16141 tacaggatgt taatatctga tatctcaact gttaacgttt gatttctcag atattaataa
    16201 ttgagaaatc aagtattaag gactgataat ttatgtatta ttgactgata tatgatttaa
    16261 tgttttcaga gagagcagta ctattgaagt agctgatgcg ttcaatgtga ttggaacatg
    16321 cggttaagtc aatcaaatca acagtagttt cagatagttt cgagcgtttg gaactaaagt
    16381 ttcaagcgta tgaaactcta gtttctcacc gatgaaacta cagtttcaca ccgatgaaac
    16441 tctggtttca agcaatggaa actctttgaa gatactgcta aattggaatt ggtgatgtgt
    16501 actggtttta gttgacaact tcgtttgtta taactgaatt agtttactca a
//
