LOCUS       gnlProkkaPHGJNCJG_21   10552 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PHGJNCJG_21.
ACCESSION   gnlProkkaPHGJNCJG_21
VERSION     gnlProkkaPHGJNCJG_21
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 21:04:18
            Original ID  :: gnl|Prokka|PHGJNCJG_21
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10552
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10552
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[282:552]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      283..552
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..10552
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10552
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             283..552
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_1"
                     /sec_met_domain="PF05402 (E-value: 2e-17, bitscore: 55.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 9.4e-10,
                     bitscore: 30.2, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLNSNLILRQVGGEYMIVNPFSETMDMAQVYSLNETAAWLWKQL
                     ENKEFTVDEAGALLCNEYEVNKDTARNDANELCRQWLETGLAIE"
     CDS             592..1644
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_2"
                     /sec_met_domain="NTP_transf_5 (E-value: 1.8e-34, bitscore:
                     111.1, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLLRQGLWDRQEDCSALFPLDEKEWNEIHSMARKQTVQGIIYDG
                     IRLLPTEAVPPRKVLLGWMVEVDTLERVNRQHRETIKALQQIYVQSPSIPFLLLKGIGT
                     ADFYPHPEHRIAGDIDLWFGNKTQTEQANQRMEKLGLPVKRGTNGEASCLINRVLIEHH
                     SRLIELHNPFLQKEIRQWEAGVFTNSQGKLPSEANHLLLSTHILKHLINEGIGLRQLCD
                     IAMAFNALHSVTNKNELECICRKWHIHRWNRLLYALLIKYLGVPADLLPFSTSLCPDKL
                     MQEIWESGNFGHGDERYGERPTGKWANKRYTLKRIFHKMHLSLGYAFDETFWWLAGLAL
                     LRFKEMIKKK"
     CDS             1641..3329
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 221.1; E-value:
                     4.5e-67)"
                     /gene_kind="transport"
                     /locus_tag="ctg21_3"
                     /transl_table=11
                     /translation="MKELLKKFLQKLTRENLSNTCQLGWKAFKWVMQVTEGYHWLITFS
                     IFSGIFGVVMSLVNVAMSKWIIDVATGTQEGNIYLVATIVALSFLLGMGIKLVSPWIFG
                     KINMRISIRMQNSLSDALMMCSWKGAGKWHTGDLLTRISSDASEVLGMGMGILPNLLVT
                     GLQLASSFIYLWILDARLAWFILGVTPLVLLSKIYFRKVRELSCAQKKMNSEMGTVMQE
                     NLSKRILVRSLGATNYRKQKLHETQEKLFKLGMEQIKFSTFTQGVMGFTFGGGYLCAFL
                     WGIFQLHNHEITFGTMTAFLQLVGQVQGPFLGLISIPPSLIRGWTSVERLMALFEDVEP
                     DEHPVYIDQPLTLNFRKVSFGYEEGQPVLDRFTAAFHPGSSTAIAGPTGTGKTTIIRLI
                     LALVYPEKGRIDLTTDDGRTLSVTPDLRINFVYVPQGNTLLSGTIRENLWLGSPGADEE
                     ALHKVIRLACAEFVFSLPEGLDTKIGEHGYGLSEGQAQRIAIARALLRPGRIWLFDEAS
                     SALDTETTTHLIDNLLQWGKNNTLIFVTHDSRLMERCDQVIHIKE"
     CDS             3351..4160
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Poly_export"
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 72.7;
                     E-value: 3.7e-22)"
                     /gene_kind="transport"
                     /locus_tag="ctg21_4"
                     /sec_met_domain="Poly_export (E-value: 1.7e-13, bitscore:
                     42.2, seeds: 183, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKTIKLACLLAIIIFSSCASRKDFVYLQDMDELQEYPMVQKYEA
                     IIHRDDRLSIIVNSKNPELSLPFNMSGSRSYSVEADGSISNNEVGVLSDEKEKGYLVDI
                     NGNIDFPVLGQLHVEGLTRRQLTELIKKRLINEELLKDPMVTVNFLNFKFSVLGEVGHV
                     GTFEVKGDRITLLEALAMAGDLTPRSRLDRIAVIREYGNKRRILFHDIRSKDIFTSPYY
                     YLQQNDIVYVEPTNMKATEQAQRKLSTWSMILSFITTITSLVLLTTK"
     CDS             4173..6584
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1216:exopolysaccharide biosynthesis domain protein
                     (Score: 284.4; E-value: 2.7e-86)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_5"
                     /transl_table=11
                     /translation="MIRMSEQKDMSGDKTLSGGGFNINPVDIIMYLLSKWYWFVLSVSL
                     FGGYAWYQYAKLPFIYSRSATVMIKDAYSNNIGRGLDRFNTYSYTNVSNEILQFQSHKL
                     MRDVVNRLHANVCYLIMDDLREEELYTQAPVKVSFPEEEDHLDFSLTVRILNRKQVRLS
                     DFSTDATSITLTANLGDTIQSPVGKIVVSPTLYYTDKWFNTPITIRRQSTDTMASLFRS
                     NLNISQAENDASILYLSLRDYSTARAEDVLNMLITVYNEETIKDKNQIAINTSSFINER
                     LVIIEKELGGVENELQSYKQNNDIIDIGSAASMSMSDKRQYSSTTQELELQARMARYIK
                     SYLVDPSKETELIPSNTGIADINIETQITAYNANKLKRDKLIEGSSDKNPIVQELNKNL
                     IAMRQNIIRAIDNMIVSIDVKLNEARSRAGEAQWRVTNIPRQQQQMLSIERQQRIKEEL
                     YLYLLNKREENALSQATTETDARVLDPAGGGDAPISPNGRSMIMAGVMKGIALPAIVLL
                     LFLFFDTRIRNRKDIEDAVTVPFLGEIPKDSSKGKTENKETAHGIAVRAQGRDIVSEAF
                     RIIRTNMDFMRVKSKNMQVVTFSSFGPGAGKTYVSSNLAASFAQTDKKVILIDMDIRKG
                     TLTSHTRLHTKEKGMTSFLAGKATTDEIIKHNEICENLDFIPAGPIAPNPSELLLSEQL
                     EVLITELRNRYDYIFVDNVPVGVVADAAITNRIADLTIFVVRVGKLDRRMLPEVEKIYR
                     SGQLNNMSLVLNGAIVKTGGYGGYGYGYGYGYGYVDGSESCWKRLFRKKS"
     CDS             6656..7327
                     /locus_tag="ctg21_6"
                     /transl_table=11
                     /translation="MKGMTDVHSHVLPGVDDGSPDINASLSLLRYMESIGLRKVWLTPH
                     IMEDYPTPNKKLRQQLDVLKAAYSGPLDLRLSSEYMMDATFTNKLDGEVLPLGSSHLLV
                     ETSYMYPPPGLPDILMKIWNAGYQPVIAHPERYLYMEEKDYLLLKEKGYSFQLNLMSLS
                     GYYGPHPKVVSEKLLKQKMYDFVGTDLHHLERYRPMLDQLRLTRRQLEALEGLIANNAR
                     I"
     CDS             7314..8318
                     /locus_tag="ctg21_7"
                     /transl_table=11
                     /translation="MRVFNCLSGGILCGLTLLLIFLPCFTPEWAGNLIFISLSAIPICI
                     ADGIIFAILLWKHNRWWMLYLLLLLGSSPILSGYFPLHFLHREEVPDSNQLKLVCWNAE
                     GFRLNKDTLAKAAHSIRILQPGIVCLQERPHTNLLAWDTIQAAFPDYPYCIINSREDEI
                     LNLAVFSRWPVGNVQEYYFPDSYNKMLQADIRMIGQTFRLFNVHLQTTGMNESSSMKDR
                     LQTMRHHAIRRNRQADLLANAIAESPYPVIVCGDFNDIPASYVYRKISRSLQDCFLQAG
                     RTWKGSYQRWGDFLRIDYTLCSPAFQVNCYQLVSNPWSDHKQQHCVLYLDKRS"
     CDS             8337..9182
                     /locus_tag="ctg21_8"
                     /transl_table=11
                     /translation="MTKENWTIEIKPKKKWLDIDLKGIWRYRDLYYMYVKRDIVTVYKQ
                     TILGPLWFLIQPIFTTVMYMFIFGGLAGISTDGVPQPLFYMAGIMLWNYFSSAFNVSSN
                     VFTANAGVFGKVYFPRLVVPLSGITSNLIKFGIQLLLFIAMYLYFYVKGASLHVNAALL
                     LFPFLTFLIAFHAMSWGLIVSALTTKYRDLTQLVTFGLQLFMYATPVIYPLNAAPEKYR
                     DIIALNPLTPIFETFKYSCMGCGSLDWGGLAYSTLFMLSTLFCSVVIFSRVERNFMDTV
                     "
     CDS             9211..10485
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 146.3; E-value:
                     1.9e-44)"
                     /gene_kind="transport"
                     /locus_tag="ctg21_9"
                     /transl_table=11
                     /translation="MNDIAIRFDHVGKLYKLGLVGTGTLSHDLNRWWKTTILRQEDPYL
                     KIGETNDRSKKGASEYVWALKDITFDVHQGDVVGIIGKNGAGKSTLLKLLSRVTSPTTG
                     AIRARGRIASLLEVGTGFHPELTGRENIYMNGSIMGMTRHEISHKLDEIVDFAGVERYV
                     DTPVKRYSSGMTVRLGFAVAAFLEPEILVVDEVLAVGDAEFQKKAIGKMQDVSKGEGRT
                     VLFVSHNMGSMQRLCSRGVLLENGKVKYMGSISDTIRTYQSDEIIQNSFEGTDGNKQIL
                     YLKKASVSSSDGNIFYNSSTIKIEFEICVKKHIPSLVIGFNLYSIFQYPLARADYNDEN
                     KKTSLEPGSYHFTFEIPPYTLSNGEYKIVFDVAERNVKCYTTKKSQLTFNVLQGEDCFG
                     NVFAEDIPIKSSLIRENWLKEIKTY"
ORIGIN
        1 agttaaagag ttctgctgtc tgatacaaga ggataaattg aattgataga actcaccttc
       61 aattcagata tgacaaacaa tacaataaga aatgttagaa gagagattcg ttttcttcgc
      121 gagaagcgcc ggatctgtaa aaaatgttag atcaggtaag ttcaagaccc tatgttatca
      181 gcggataata gaatgaactt acattttatt ccccattaca tctgcctgtg aaggtcgatg
      241 taattttaac tataaatagg ataatgcaat aatataaaga caatgagact caattctaat
      301 ttaattcttc gccaagtagg tggagaatat atgattgtca atccgttttc tgaaaccatg
      361 gatatggcac aggtctattc cttgaatgaa acagccgcct ggctatggaa acaattggaa
      421 aacaaggaat tcacggtaga tgaagccgga gcactgctgt gcaatgaata tgaagtaaat
      481 aaagatacag cccgaaacga tgccaacgag ctgtgccgac aatggttaga aactgggtta
      541 gccatagaat aagacaaaaa gatgatctca gccccattac aaaaggcttt catgcttttg
      601 ctaaggcaag gactgtggga ccggcaggaa gactgttccg ccctttttcc tctagatgaa
      661 aaggaatgga atgaaattca cagcatggca agaaaacaaa ccgtacaagg cattatttac
      721 gatggcatcc gcctgttgcc gactgaagcc gtacctcccc ggaaggtatt gcttggctgg
      781 atggtggaag ttgacacctt ggaacgggtg aaccggcaac accgggaaac gattaaagcc
      841 ctccaacaga tttatgtaca atcaccttct atccctttcc tgctgctaaa agggataggg
      901 acagctgact tctaccctca tccggaacat cgcatagccg gagacatcga cctgtggttc
      961 ggaaacaaga cacaaaccga acaagccaac caacggatgg aaaaattagg attaccggta
     1021 aaaagaggaa ccaatggtga ggcttcctgt ctgataaaca gagttctgat tgaacatcac
     1081 agcaggctga tagagttgca caaccctttc ctccaaaaag aaatccgcca atgggaagcg
     1141 ggggtcttta ccaacagcca aggcaaactt ccgagcgaag cgaatcatct attactttcc
     1201 acccacatat tgaagcatct tatcaatgaa gggatcggac tacgacaatt gtgtgatata
     1261 gccatggctt ttaacgcatt acattctgtt acaaacaaaa acgaattaga gtgtatctgt
     1321 cgcaaatggc acattcaccg gtggaaccgg ttactttatg ccctattgat aaaatatctt
     1381 ggcgtgccgg ccgacctttt accattcagt accagtctct gtccggacaa gttaatgcaa
     1441 gagatttggg aaagtggcaa ttttggacat ggagacgaac gttacggtga acgtcccacc
     1501 gggaaatggg cgaacaaacg atacacgttg aagcggatct ttcacaaaat gcacttatcg
     1561 ttaggttatg ctttcgacga aactttctgg tggctggccg gattagccct cttacgtttc
     1621 aaggaaatga taaaaaagaa atgaaagaat tgctgaaaaa atttttgcag aagctcacac
     1681 gggagaatct gagcaataca tgtcagttag gatggaaagc tttcaaatgg gttatgcagg
     1741 taacagaagg ataccattgg ctcatcacct tctctatctt ttcgggtatt ttcggagtgg
     1801 tcatgtcatt ggtcaatgtg gccatgtcca aatggatcat cgatgtagct accggaacac
     1861 aggaagggaa tatttacctg gtagccacaa tagtagcctt atccttcctg ctgggtatgg
     1921 ggataaaact tgtatctccc tggatttttg gcaagatcaa catgcgcatc agtatccgca
     1981 tgcaaaattc gctgtccgac gccctaatga tgtgttcatg gaaaggagca gggaaatggc
     2041 acacaggcga cctgctgacc cgtatcagca gtgacgcttc cgaagtgttg ggaatgggaa
     2101 tgggcattct acccaacctg ctggttaccg gcttgcaatt ggcaagctct tttatctact
     2161 tgtggattct tgacgcgcgt ttagcttggt tcatactggg agtcacccct cttgttttat
     2221 tgtcaaagat ttatttcaga aaggtccggg aactgagctg tgcccaaaaa aagatgaaca
     2281 gcgagatggg taccgtcatg caagaaaatc tgtccaaacg gattctagtc cgctcgctcg
     2341 gagccaccaa ctaccggaaa cagaaattac atgaaacaca agagaagttg ttcaaattgg
     2401 gaatggaaca aatcaaattt tccactttta cgcaaggggt catgggattt acatttggag
     2461 gagggtactt atgtgcattc ctttggggta ttttccaact gcataaccac gagataacat
     2521 tcggaacaat gacagccttt cttcaactgg tcggacaggt acagggacct tttttagggt
     2581 taatatccat ccctcccagt ctgatacggg gatggacctc cgtggaacgg ttaatggccc
     2641 tctttgaaga tgtagaaccg gacgaacacc cggtctacat agaccaacca ctgacactga
     2701 actttcggaa agtgtctttt ggctatgaag agggacagcc ggtactcgac cggtttacag
     2761 ctgcctttca tccgggaagt tccaccgcca tagccggacc taccggaaca ggaaaaacga
     2821 ccattatccg gctgatactg gctttggttt atccggaaaa gggacgcatc gatttgacaa
     2881 ctgatgacgg acggacactc agtgtgaccc ccgatttacg catcaacttc gtctatgtgc
     2941 cccaaggaaa tacgttgctg agcggtacca tccgggagaa tttatggctg ggtagtccgg
     3001 gagcagacga agaggctctg cataaagtca tccggctggc ctgcgctgaa tttgtgttca
     3061 gtctgccgga aggactagat accaagatag gggaacatgg atatggcttg tctgaaggac
     3121 aagcccaacg gattgcaata gcccgcgcac tgttgcgtcc cgggcggatc tggctgtttg
     3181 atgaagcatc atcggcactt gacaccgaga ccaccacaca cctcatagac aatttgttgc
     3241 aatggggaaa gaataacaca ttaatatttg tgacacacga ttcacgactg atggaacgat
     3301 gtgaccaagt gattcatata aaggaataaa aaacaattaa ttataaaaca atggataaaa
     3361 caatcaaact ggcctgtctg ttggcaataa tcatttttag ttcgtgcgct tcacgcaaag
     3421 attttgtcta tttacaagat atggatgaac tacaggaata tcctatggtt caaaaatatg
     3481 aagccatcat ccatagggat gacagattga gtattattgt gaacagcaaa aacccagaac
     3541 tgtccctgcc tttcaatatg tccggaagca gaagctattc tgtagaagca gacggaagca
     3601 tttccaacaa tgaagtgggg gtattaagtg atgaaaaaga aaaaggttat ttagtggata
     3661 tcaacgggaa tatagacttt cctgtgctgg gacaactgca tgtggaagga ctgacccgcc
     3721 gacaattaac cgaactgatc aagaaacgac tgatcaacga agaattgctg aaagatccta
     3781 tggtcaccgt caatttcctt aacttcaaat tttccgtgct gggagaagtt ggacatgtag
     3841 gaacctttga agtgaaaggc gaccgcatca ctcttctgga ggctcttgcc atggccggag
     3901 acctgacccc ccgatcccgt ctggaccgta tcgccgtcat ccgcgaatat gggaacaagc
     3961 gacgaatcct gttccacgac atccgcagta aagacatctt cacatcgcct tactattacc
     4021 tgcaacagaa tgacatcgtt tacgtagaac ccaccaacat gaaggccacc gaacaggccc
     4081 agagaaaact gagcacgtgg agtatgatcc tgtccttcat caccacaatc acctcactgg
     4141 tgttgttaac tactaaataa aaaagaaacg acatgataag aatgagtgaa caaaaagata
     4201 tgtcgggaga taagacctta agcgggggag gattcaatat caaccccgtt gacatcatca
     4261 tgtacctgtt gtccaaatgg tactggtttg tattgtcggt cagtctgttc ggcggatatg
     4321 catggtatca atatgccaaa cttcccttta tctattcacg gtcagccacc gtcatgataa
     4381 aggacgccta ttcaaacaac atcggtcgcg ggctggaccg ttttaacacc tattcatata
     4441 ccaatgtatc caatgagatc ctgcaattcc agtcacacaa actcatgcgc gatgtggtga
     4501 accgtcttca cgccaatgta tgctacctca tcatggatga cttgcgtgag gaggaacttt
     4561 atacgcaagc ccctgtcaag gtttcattcc cggaagaaga ggatcatctt gatttcagcc
     4621 tgacagtcag aatcctgaac aggaagcaag tccggttatc cgatttctcg acagacgcca
     4681 caagtataac gctgacggcc aatctgggtg acactatcca gtcgcccgta ggaaaaatag
     4741 tggtctcacc caccttatat tatacagaca agtggttcaa cacaccgatt acgatacgcc
     4801 ggcagagtac ggacacaatg gccagcctat tcagaagcaa cctgaacatc agccaagctg
     4861 agaatgacgc ctccatcctc tacctgtcac tccgtgatta ctccaccgcc cgtgccgaag
     4921 atgtgctcaa tatgctgatt acagtgtata atgaagagac tatcaaagac aagaaccaga
     4981 tagccatcaa tacctccagc ttcatcaacg agcgtctggt catcatcgaa aaagaactgg
     5041 gaggcgtgga aaacgaactt cagtcctaca aacagaacaa tgacatcatc gatatcggtt
     5101 cagccgcttc catgtccatg tcagacaaac ggcagtacag ctcgaccact caggaactgg
     5161 aattacaggc acgcatggca cgctacatca agagctacct ggtggacccg tccaaagaaa
     5221 ccgagcttat cccttcaaac accggcatag ccgacatcaa cattgaaacc cagataacgg
     5281 cctataatgc caacaagttg aaacgggaca aactgataga aggaagcagc gacaagaatc
     5341 ccatcgtcca ggaactgaac aagaatctga ttgccatgcg gcagaatatc atccgggcca
     5401 tcgacaatat gattgtcagc atcgacgtga aactgaacga ggcacgaagc agggccggag
     5461 aagcccagtg gcgggtaacc aacataccta gacaacagca gcaaatgctt tctatcgaac
     5521 gtcagcaacg catcaaagag gaactttacc tctatctgct gaacaaacgc gaagaaaatg
     5581 cgctgagcca ggccaccacc gagactgacg cccgtgtgct cgatcctgct ggaggagggg
     5641 atgctccgat ttctcccaac ggacgcagca tgatcatggc aggtgtcatg aaaggaatcg
     5701 ccctgccggc aattgtcctg ctattgttcc tgttcttcga tacccgtata cgcaaccgca
     5761 aggacatcga ggatgctgta accgttcctt tcctgggcga aatacccaag gattcatcca
     5821 aagggaaaac agagaataaa gaaacggcac atggcatcgc tgtccgtgcc caagggcgtg
     5881 acattgtatc ggaagccttc cgcataatac gcaccaacat ggattttatg cgtgtcaagt
     5941 caaagaacat gcaagtcgtc actttcagct cgttcggacc gggtgccggc aagacatacg
     6001 tatccagcaa tctggcagcc agcttcgcgc aaaccgacaa gaaggtcatc ctgattgaca
     6061 tggatatccg taaagggact ttgacttcac atacccgcct ccacacaaag gaaaaaggaa
     6121 tgacctcttt tctggcaggc aaggccacaa cggatgaaat catcaagcac aacgagatct
     6181 gtgaaaatct ggatttcatt ccggccggtc ccatcgcccc caacccgtca gagctattgc
     6241 tcagcgaaca actggaagta ctgataaccg aactgcgcaa ccgttatgac tatatctttg
     6301 tcgacaatgt gcctgtagga gtggtggccg atgccgccat caccaaccgc atagccgacc
     6361 tgaccatctt cgtggtacgg gttggcaaac tggaccgccg catgttaccg gaagtggaaa
     6421 aaatttatcg cagcggacaa ctgaacaaca tgtcgttggt acttaacggg gccatagtaa
     6481 agacaggcgg atacggaggc tatggatatg gttacggcta cggctatggt tatgtggatg
     6541 gttccgaatc atgctggaaa cggctgttca gaaagaaatc ctaaaatccc cccaaaaaag
     6601 aagtaggatg tttggtatat tcaagtccaa atacaatttg attaattctg gtttaatgaa
     6661 gggtatgacc gatgtccatt cccatgttct tccgggagtg gacgacggtt cgcccgacat
     6721 aaatgccagt ctgtccctgc tgcgctatat ggaatccata gggttgcgga aagtgtggct
     6781 caccccccat atcatggagg attatcccac accgaacaag aagctgcgac aacagctcga
     6841 cgtgttgaag gcggcctatt ccggcccgtt ggatctacgg ctgtcttccg aatatatgat
     6901 ggatgccact tttacaaaca agctggatgg agaagtgctg cctttaggca gcagccacct
     6961 gctggtcgag acatcctaca tgtaccctcc tcccggtttg ccggatatcc tgatgaaaat
     7021 atggaatgcc ggttatcaac cggtcatcgc ccacccggag cgttacctgt acatggaaga
     7081 aaaagattac cttctgctga aagagaaagg ttacagcttt caactcaatc tgatgtcact
     7141 gagcggttac tatggcccgc accccaaagt ggtcagcgaa aagctgttaa aacaaaaaat
     7201 gtacgatttt gtgggtacgg acctgcacca tttggagcgt taccggccca tgcttgacca
     7261 attgaggttg acccgaagac aactcgaagc tttagaaggt ctgattgcca acaatgcgcg
     7321 tatttaactg tctgtcggga ggtatcctgt gcggtctgac actgctgttg atatttctcc
     7381 cctgcttcac tcccgagtgg gccggaaatc ttatcttcat cagtctatcg gcgattccta
     7441 tatgtatagc cgatgggatt attttcgcga ttctgctttg gaaacataat cgttggtgga
     7501 tgctttactt gcttttgcta ttaggtagtt cacctattct atccggttac tttccgcttc
     7561 atttcctaca tagagaagaa gtgccagatt ccaatcagct aaaactggtt tgctggaatg
     7621 ccgaagggtt cagactgaac aaagacaccc tggcgaaagc cgcccatagc attcgtatcc
     7681 tgcagcccgg catcgtctgt ctgcaggaac gtccccatac caatcttctg gcatgggaca
     7741 ccatccaggc tgcttttccc gattacccct attgcatcat caactcgcgg gaggatgaaa
     7801 ttcttaatct ggccgtcttc agccgctggc ctgtcggaaa cgttcaagag tactacttcc
     7861 cggacagcta caataagatg cttcaagcgg atatccggat gatagggcaa actttccggt
     7921 tattcaatgt ccatctgcaa actaccggca tgaatgaatc atcctcaatg aaagacagac
     7981 tccagacgat gcgccaccac gccatccggc gtaaccggca agccgatctc ttggcaaacg
     8041 ccattgccga gagtccttac ccggtcatcg tgtgcggtga tttcaacgat ataccggctt
     8101 cgtatgttta ccggaaaatc agccggtcac tgcaggattg cttcctccag gccggccgga
     8161 catggaaagg cagctaccaa cgctggggcg attttttacg aatagattat acgctctgtt
     8221 cacctgcatt ccaagtgaat tgttaccaac tggtttccaa tccctggagc gaccacaaac
     8281 agcagcactg tgtgctctat ctggacaaac gctcctaaaa aacaagattt caaaaaatga
     8341 ctaaagaaaa ctggacaata gaaataaagc caaagaaaaa atggctggat atagatctga
     8401 aaggtatatg gcggtaccgt gacctatact atatgtacgt gaaacgcgac attgtcaccg
     8461 tgtacaaaca aactattctg ggtcctctct ggttcctcat ccaaccgatc ttcactaccg
     8521 tgatgtatat gttcatattc ggtggcctgg caggtatctc gacggacgga gtaccacagc
     8581 ctttattcta catggcaggt atcatgctgt ggaattattt cagttccgcg ttcaacgtat
     8641 cctccaatgt gttcacggcc aatgcgggcg tgttcggcaa agtctacttc ccccgtctgg
     8701 tcgtgccgtt gtccggcatc acctccaacc tgatcaagtt cggaatacaa ttgttgttgt
     8761 tcattgccat gtatctctat ttttatgtga aaggagcttc actgcatgtc aatgccgccc
     8821 tgctgttgtt tccgttcctg acatttctga ttgcattcca tgccatgtcg tgggggttga
     8881 tcgtatcggc gctgaccacc aaataccgtg acctcaccca gttggtcacc ttcggcctgc
     8941 aactgttcat gtatgccact ccggtcattt atccgctaaa cgcagctccg gaaaaatacc
     9001 gtgacatcat cgcgctcaac ccgttgaccc ccatattcga gacctttaaa tacagctgca
     9061 tggggtgtgg ttcacttgat tggggcggat tggcatatag cactttgttt atgctctcca
     9121 ccctgttctg ctcagtagtc atcttcagcc gggtggaacg caattttatg gatacagtgt
     9181 aagcagcaga attaaaaaaa gagaataaga atgaacgata tagcaatccg gtttgaccat
     9241 gtgggcaaac tctacaaact cggtctggtc ggcaccggca cactgagcca cgacctcaac
     9301 cgctggtgga aaacgaccat tctccgccag gaagacccct atctgaagat aggcgaaacc
     9361 aacgaccgca gcaagaaagg cgcgtcggaa tatgtctggg cgttgaaaga catcaccttc
     9421 gatgtgcatc aaggcgatgt agtaggcatt atcggaaaaa acggtgccgg gaagtccacc
     9481 ttgttgaaac ttctgtcgcg tgtcacctcc cctaccaccg gagccatccg tgcccgtggc
     9541 cgcattgcct ctctcttgga agtcggtacc ggtttccatc cggaactgac cggccgtgag
     9601 aacatctaca tgaacggctc catcatgggc atgactcgcc acgaaatctc ccacaagttg
     9661 gacgagatag tcgactttgc cggtgtggaa cgctatgtag atacccccgt aaaacgctat
     9721 tccagcggca tgaccgtccg tctgggcttt gccgtagccg cttttctgga accggaaata
     9781 ctggtagtag atgaggtact tgccgtaggt gatgccgaat tccagaagaa agctatcggc
     9841 aagatgcagg acgtgtcgaa aggcgaaggg aggacggtgt tgtttgtgag tcataatatg
     9901 ggtagtatgc aacggctatg ttcacgtgga gtattattgg aaaatgggaa ggttaaatat
     9961 atgggaagca tatccgatac catccgtact tatcaaagtg atgaaatcat tcaaaactca
    10021 tttgaaggaa ctgacggaaa caaacaaata ctctatttga aaaaagcctc tgtttcatcc
    10081 agcgatggaa acatattcta caattcttct actattaaaa tagaatttga aatatgcgta
    10141 aagaaacata ttccttcttt ggttattgga tttaatctat atagcatctt ccaataccca
    10201 ctggcacgag ccgactacaa tgatgagaac aaaaagacat cgctagaacc gggaagttac
    10261 cactttactt tcgagattcc tccttacacc ctatccaatg gagaatataa aattgttttt
    10321 gatgtggcgg aaagaaatgt aaagtgctac acaacaaaaa agtcgcaatt gacattcaat
    10381 gtacttcaag gggaagattg cttcggtaat gtatttgcag aagatattcc cattaagtct
    10441 tctcttatca gagaaaattg gttgaaagaa attaaaacat attaaatcag catgaaatta
    10501 tctgtcgcac tttgcaccta ttaatgatga aaaatatata aaaaaacaat ta
//
