LOCUS       gnlProkkaPHGJNCJG_56   10355 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PHGJNCJG_56.
ACCESSION   gnlProkkaPHGJNCJG_56
VERSION     gnlProkkaPHGJNCJG_56
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 21:04:18
            Original ID  :: gnl|Prokka|PHGJNCJG_56
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 276523
            Orig. end    :: 286878
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10355
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10282]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10282
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..10355
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10355
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             937..2109
                     /locus_tag="ctg56_224"
                     /transl_table=11
                     /translation="MKKHFIAFMMPFLTLATGFAQEAAQDVPVKQDTKEISYWTDPASG
                     DKRLLNKSKFRDNWFVGLQAGAFYSWGTHTSSSGFFDQFRPAGALSIGKWIAPAGGIRL
                     QGFYGSNAGRASNDKPYYWDAMGVGLDGLFNFTNLFCGYEEDRTFNLIGILGAGYEHTA
                     NFSKRTWNDGIYNTESQDLLSIRLGLMAKFRLGKAWDFNLEITNSLLDDSFDGWEGEGS
                     NDRWDGHVNILAGVSYRFKNHNGSRQFTYARRDMSKYDEANAEINRLREANKAAAPPVT
                     KIETEVVESNHIRSFISFDNASAAINKLQEVNVYTAAENIKKLADGDLYITSTKEVRDT
                     ELFMARAQSIRNVLANTYDIPAGRIFIEKNPAVIASLDPQKSCVIVYINE"
     CDS             2138..3364
                     /locus_tag="ctg56_225"
                     /transl_table=11
                     /translation="MKKIAILFVVFFCSVSLWAQTIEDDATWKLKTDTVRALKHYKAGD
                     NWFIGIQAGANHSLSENSRFGSFGAMTRPSIALSVGKYFSPAIGARVQLAYLKQMSRAN
                     SEVIEAFPEVYGKGNYGFNMFNGYLDGLFNLHNIFAQYDEDIRFNVVGILGMGFNSSFG
                     FDDKVKEWDKSPSEEFAPYQISTDNKTFFSLRAGLQFNYMLSNALDINLEATFNATDDA
                     FNGTRYDRKWDSYANVMLGLTYHFKDQYGDRRFRYTEVNDQAWVDELNRKINEERNKPV
                     PAPVVTEVKKEVVKNEMLGMTVSFIIDKYNITDIQKKNVAEAAKYLEDHPEVNLIITGY
                     ADVQTGNPAYNLKLSQRRAEAVCNMMVKEFGVDPSRIRVDYKGDSLQPYQLKNEWNRVV
                     VFITEARNK"
     CDS             3385..4530
                     /NRPS_PKS="Domain: Aminotran_1_2 (37-168). E-value: 4e-09.
                     Score: 27.9. Matches aSDomain:
                     nrpspksdomains_ctg56_226_Aminotran_1_2.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     315.1; E-value: 1.1e-95)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg56_226"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2.3e-98,
                     bitscore: 323.6, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.7e-08, bitscore:
                     27.9, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKIWLSLAHMGGSEQEFVREAFETNWVVPLGPNVDGFEHDLSQW
                     LSTHCDREVHAVALSSGTAAIHLALIMLGVSKGDEVICQSFTFAASANPICYQGATPIF
                     VDSEPDTWNMDPILLEQAICDRMKQTGLKPKAILPVHLYGTPARMNEICDIASRYGIPV
                     VEDAAEAMGAVYDGRYCGTFGQYGIFSFNGNKMITTSGGGALLCHTEEEAQRVKFYATQ
                     AREPFPWYQHEQIGYNYRLSNVSAGIGRGQMRVVDNHIAHRRAIHRLYTELLAGLPGIT
                     VVEPKKSTIFLPNYWLTTIKVDSNETSFSALQLMQHLAKADIETRPLWKPLHLQPVFSS
                     SPTYVNGVSEALFNCGLCLPSGSMMTCEDVMRVADAIRSMR"
     aSDomain        3496..3888
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg56_226_Aminotran_1_2.1"
                     /evalue="4.00E-09"
                     /label="ctg56_226_Aminotran_1_2.1"
                     /locus_tag="ctg56_226"
                     /protein_end="168"
                     /protein_start="37"
                     /score="27.9"
                     /tool="antismash"
                     /translation="FEHDLSQWLSTHCDREVHAVALSSGTAAIHLALIMLGVSKGDEVI
                     CQSFTFAASANPICYQGATPIFVDSEPDTWNMDPILLEQAICDRMKQTGLKPKAILPVH
                     LYGTPARMNEICDIASRYGIPVVEDAA"
     CDS             4831..5220
                     /locus_tag="ctg56_227"
                     /transl_table=11
                     /translation="MTKKVYTKPELKSEAFVPQTHVAACGDSGTVYKFTCDAPRGTLYY
                     FRDKPASGSQPTTGNRGIWLGNYHPCSAFHEAEAQSGFYWGYVDYNHNQKFEKSELVIV
                     WRGQKGWEGHATKNLDINSWETAKS"
     CDS             5561..5956
                     /locus_tag="ctg56_228"
                     /transl_table=11
                     /translation="MKKDYQKPMLISEEFIPNEYVAACYNFKALFHCHYGENNTNNHGK
                     PCATTYVDINGIHATGHEGTIEKWGIPILNIDWNGFDLSDAKVGDEIRGIKWTSYDTVN
                     NTGEYNHQGWGEIKSAVEEIPGRPNHS"
     CDS             6412..7515
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg56_229"
                     /sec_met_domain="PF04055 (E-value: 1.1e-29, bitscore: 97.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESLQDINPVERALVNKATANRTPINATIELTPTCNFRCDMCYIR
                     MEKSQAEKRGGLRSIEEWLHIADQLQEIGTLFILLTGGEPLLYPDFKELYIRLKEKGFI
                     LTINTNATLIDDETVRLFQRLKPRRVNVSLYGVTNGTYLNLCHATNGFDRCLEGLKRLK
                     EYGIDTKLNLTLTRQNIKEHRQMLELADEWDLPMLTNSYISVYSRPGCATTLPLDTCRP
                     VPDEVAHAEVEALEHKYGKEYTSYATHVLQQLERGESPVPAEGIGLACRAGKSSAWINW
                     QGVMTPCVDMETPAVSLLSTTVSDAWKQIVTKCEQLPFHKECAGCTLRSICDVCYANAR
                     NEKGQCGGIGYLCRIAKSKKKQMKGSL"
     CDS             7551..8657
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg56_230"
                     /sec_met_domain="PF04055 (E-value: 1.6e-23, bitscore: 77.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHLHDANLLERALVDKANQSRVPITTNFELTPTCTLNCDMCFIR
                     TERSVVERHGGLSPLQQWLDWAEQLQDMGTLFILLTGGEPMLYPHFKELYTRLREMGFI
                     LTLNTNGTLIDNEMVRILQTHKPRRINVTLYGDSRETYGRLCHNPQGYTLCMEALKRLK
                     KADIDVKLNVSIVRKNEKDYDEIIRLAQHLDIPAEVNSYMFPLSRPECGSLRNILTERL
                     DADEAARIEMQYMEYKKGNDMARYMHDLKYTLAHVEGTRACSLECRAAKSSCWINWQGI
                     LTPCVMLDQPAVDLKKIPMTTAWQQLLEEAKELVSHTECEGCHLRPVCNVCYAAAHCEK
                     TITGSMDYLCQMAKAKERIITNYPPVIH"
     CDS             8670..9545
                     /locus_tag="ctg56_231"
                     /transl_table=11
                     /translation="MRLNIGPLTIELSGVTEQEIPVNSRLFLDHKPATKEADRYYTFYF
                     VNRLPLPSNDWQITFQRNDIVVFRKEEQETRLLAVGNLNACYALYQERNERDANIYFIE
                     GLKRELQTDTLFISCLCLERPLSVQGCYILHCTFLDYRGQAILFSGPSGIGKSTHANLW
                     CRHIPGTQVLNGDRALLCPLPNGDYEITGWPVCGSSGICHNERRPLEAIVFIEQASDNT
                     IRPQTAMKHFKALCSQVTINWWNPKLTGKALDDLQVLTRQTSISTYACNMNPEAAFTLH
                     RYLTKLEIIR"
     CDS             9564..10004
                     /locus_tag="ctg56_232"
                     /transl_table=11
                     /translation="MKTVDTKEYISMLRTLIEEGKQVSMIISGSSMAPFLIHARDHIYL
                     KSPSGELRKGDMVFYQRSNGEYVMHRIYNVKNEEYYLIGDAQTVIEGPIQREQIFAIII
                     KVKRKGKWIVPEDFQWKFFAHIWPNIIPLRRTIIKTYRFFKR"
     CDS             10001..10282
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_233"
                     /sec_met_domain="PF05402 (E-value: 2.7e-16, bitscore: 53.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1e-13,
                     bitscore: 45.1, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRTKEFIKRNIAGEIVLVPSGQTAREFNGMVTLTETGEFIWEHI
                     EEAESFNHLVLLILEEYEVDKDTASQDAAGFIMQLLQAGMIRPTGINW"
ORIGIN
        1 ccatcctgcc tatcataggt gatgtacgca accgtgaccg tgtggagtcg cagacaagac
       61 tctaccaccc cgacatcatc tttcatgcag ccgcatacaa acatgtaccc atgatggaaa
      121 aatatccatg cgaggcggta cgtaccaatg tcctgggtac aagcatcatg gcagatacgg
      181 cattgaaata tggcgtaaag aaattcatca tgatctccac agacaaagct gtaaatccca
      241 gcagtgtgat gggtgctacc aaacgactgg cagagatgta cgtacaaagc ctcgggagtg
      301 ctatccaaga aggaaatata attggtaaaa cctcttttat aaccacccgt ttcggcaatg
      361 tgctgggcag caacggcagt gtaatccccc ttttccgcca acagattatg gaaggggggc
      421 ctgtaacagt cacgcatccg gacatcatcc gttatttcat gactattccc gaagcttgcc
      481 gactggttct agaggccgct tttatgggac aaggaaacga tatctttatt ttcgacatgg
      541 gtaaacccgt aaaaataacc gacatggcat gccggatgat aaaactggca ggtttacaac
      601 cggacaaaga cattgaaatc gtctataccg gtctgcgacc gggcgagaaa ctatatgagg
      661 aattactcta taatgaagag aactctactc ctacccttaa tccgaaaata ttcaaaggta
      721 tcagtttaaa acaagattac gataaaataa agcccgccct gcaacaattg gttgaggttg
      781 cccagacgga caataaaaaa gagaccgtat atcagttgaa gcaaattgta ccggagttca
      841 aaagtatgaa ctccgtatat gaggcgctgg atgaaaaaac atatatatcc aaaaaaatga
      901 aatccaatat aatgtttaac taaaatgaat cgcaaaatga aaaaacattt cattgcgttt
      961 atgatgccat ttctaacctt ggctacggga tttgcacaag aagcggctca agatgttcct
     1021 gtcaaacagg atacaaagga gatctcttac tggacagacc ctgcaagcgg ggacaaacgg
     1081 ctcttaaaca agtctaaatt cagagacaac tggtttgtcg gattgcaggc cggcgccttt
     1141 tattcctggg ggacccatac ttccagttct ggattcttcg accagttccg tcccgccggt
     1201 gcgttgtcca taggcaagtg gatcgctcct gccggaggta tccgcctcca aggtttctat
     1261 ggaagcaatg ccggacgagc aagcaacgac aagccctact attgggacgc catgggggta
     1321 ggtctagacg gattgttcaa cttcaccaac ctcttttgcg ggtatgaaga agaccggacc
     1381 ttcaacctga tcggtatctt gggagccggt tacgaacaca ccgccaactt cagcaagcgt
     1441 acctggaacg acggaatata caataccgaa tcgcaagacc tgctgtccat ccgcctgggt
     1501 ctgatggcga aattccgcct cggtaaagcg tgggacttta atcttgaaat cacgaacagt
     1561 ttgcttgacg actcattcga cggttgggaa ggcgaaggtt caaacgaccg ctgggatggc
     1621 catgtcaaca tattggcagg tgtcagctac cgtttcaaaa atcataacgg ctcacggcaa
     1681 ttcacctacg cccgccgcga catgtcgaaa tatgacgaag caaacgccga aatcaaccgc
     1741 ctgcgtgaag ccaacaaagc ggcagctcct cctgtcacaa agattgagac agaagtggtg
     1801 gaaagcaatc atatccgttc gtttatctcg tttgacaatg cttccgccgc aatcaacaaa
     1861 ctacaggaag taaacgttta cacagcagca gaaaatataa agaagctagc cgatggcgac
     1921 ctctatatca cttcaaccaa agaagtaaga gacaccgaat tgttcatggc acgggcacaa
     1981 tccatccgca atgtgctagc caacacatac gacattccgg ccggacgtat ttttatagag
     2041 aaaaaccctg ctgtcattgc atcgctcgat ccacaaaaga gctgcgtcat agtgtacatc
     2101 aatgaataaa cgacccattt taaaagtata atttggcatg aaaaaaatag ctatattatt
     2161 tgtggtcttc ttttgttctg tatctttatg ggcacaaaca atagaagacg atgcaacttg
     2221 gaaattaaag accgacactg tacgggcgct aaagcattac aaggccggtg acaactggtt
     2281 catcggaatt caggccggcg ccaatcattc gctgtccgag aacagccgct tcggatcttt
     2341 cggcgccatg accagaccaa gcatagccct ctcggtcggt aaatacttct cacccgccat
     2401 cggagcacgt gtgcaactcg cttatttgaa acaaatgtca cgcgccaaca gcgaagtgat
     2461 tgaagccttt cccgaggtgt atggcaaagg gaactacggt ttcaatatgt tcaacggtta
     2521 tttggacgga ttgttcaacc tgcacaatat tttcgcccaa tatgacgaag atatccgttt
     2581 caatgtagta ggtatcttgg gtatgggatt caactccagt ttcggattcg atgataaagt
     2641 caaagagtgg gacaaatccc ccagtgagga gtttgccccc taccaaatca gcactgacaa
     2701 caaaacgttt ttctctctac gcgcaggcct ccagttcaat tatatgttga gcaatgcgct
     2761 tgacatcaat ctggaagcga ccttcaacgc aacggacgat gctttcaacg gtacgcgtta
     2821 cgaccgcaaa tgggattcat acgccaacgt catgttaggt ctcacctatc atttcaagga
     2881 ccagtacggc gatcgccgct tccgctacac agaggtgaac gaccaggcat gggttgacga
     2941 attgaaccgc aagatcaatg aagagcgtaa caagccggta ccggcaccag tcgtcacaga
     3001 agtgaagaaa gaggtagtga agaacgaaat gttgggtatg accgtatcat tcattatcga
     3061 caagtacaat attaccgata tccagaaaaa gaatgtggca gaagctgcca agtatttgga
     3121 agaccatccg gaagtcaacc tgatcataac aggttatgcc gacgtacaga ctggtaatcc
     3181 ggcctacaat ttgaaattga gccagcgccg tgccgaagct gtctgcaaca tgatggtgaa
     3241 agagttcggt gtggatccaa gccgcatccg ggtggattac aaaggtgata gcctgcaacc
     3301 ataccagctg aagaacgagt ggaaccgtgt tgtagtgttc atcaccgaag cacgcaacaa
     3361 ataatttttt gttcataact gaaaatgagt aagatttggt tgtcattggc acacatgggc
     3421 ggatccgaac aagagttcgt ccgtgaggct ttcgaaacca attgggtagt tcccttaggg
     3481 ccgaatgtag atggcttcga gcatgacttg tcacagtggc tttcaacgca ttgcgaccgg
     3541 gaggtacacg ccgtggcatt atcatcaggt acggcagcca tccacttggc attgatcatg
     3601 ctgggcgtaa gcaaaggaga cgaagtgatc tgccaaagtt tcacctttgc tgcgtcagcc
     3661 aaccccattt gttatcaggg tgctaccccc attttcgtgg acagtgagcc tgatacttgg
     3721 aatatggatc ctatactgct tgaacaggcc atctgcgacc gtatgaaaca gaccggcctc
     3781 aagcccaaag ccattcttcc agtacacctt tacggcacgc ctgcccgcat gaacgaaatc
     3841 tgtgacattg cctcccgcta cggcatcccc gtggtggaag acgctgccga agcaatgggg
     3901 gccgtttacg acggacgcta ttgcgggacc ttcggtcaat atgggatttt ctcttttaac
     3961 ggcaacaaga tgatcaccac cagcggtggc ggagccttat tatgccatac ggaagaggaa
     4021 gcccagagag tgaagttcta tgctacccag gcacgtgaac cgttcccctg gtaccagcac
     4081 gaacagatcg gatacaatta ccggctcagc aatgtgtcgg ctggtatcgg acgcgggcag
     4141 atgcgtgtag tggacaacca tatcgcacac cgccgtgcca tccatcggct atacaccgag
     4201 ctgctggcag gacttccggg tatcactgtg gtagaaccca agaaatctac catatttcta
     4261 cccaattatt ggctgactac aattaaagtg gacagtaacg aaaccagttt cagcgccttg
     4321 cagctgatgc agcacttggc aaaagccgac atcgagaccc gtccgctttg gaaaccgtta
     4381 cacctgcaac ccgtattctc atcctccccc acctacgtca acggagtatc ggaagccctg
     4441 ttcaactgtg gactctgtct gccttcggga tcaatgatga cgtgcgagga tgtgatgcgt
     4501 gtagcggatg cgatacggag tatgagatag ataatttatt taataacaga cagagttctg
     4561 caagaacttg gctatatgaa agtttcatag taaagagaaa attgtaagat gttaggaatt
     4621 tggagatgga acgtgaacaa gccgaaagcg acatgtcaca tccggatatt tatctccgta
     4681 aatcggtaaa gactgtaaat cacagtcgtt tcatcctttt tattcttgat tcttattgat
     4741 tgagttcttg cagaactcgg tcatgttttt cccttttcaa acttttgccc tcttacagaa
     4801 taagaagtct ggcaaaacaa gaaaaaaaag atgacaaaga aagtttatac aaagccggag
     4861 ctgaaaagcg aggctttcgt gccgcaaacg catgtggctg cttgtggaga tagtggaact
     4921 gtttataagt ttacttgtga tgcaccaaga ggaacgttgt attattttag agataagcct
     4981 gcttctggtt cacaacccac tacaggaaat cgaggtattt ggctaggaaa ctatcatcca
     5041 tgtagtgcat ttcatgaagc cgaagcccaa tctggttttt attggggata tgttgattac
     5101 aaccataatc agaaatttga gaaaagtgaa ttagtcattg tttggagagg acaaaagggc
     5161 tgggagggtc acgccaccaa gaaccttgac ataaattctt gggaaactgc taaatcctaa
     5221 tcggtaaata aaacagtaaa tcgcaatctt attcatttat ttcaatcttg attcctaacg
     5281 cttagataaa tttattgatt ctcattaata gaaatagaga ttaaataata tatgatcaga
     5341 ctactggagg aactaagtca gaatatcgtt tgagctgcaa agaattagtg taatgaaaag
     5401 gaaaatgaaa ggatcatatt gtagatggta aatcgcaata tatcaattat ttcaaaattc
     5461 tttcacaccg gagtttctcc gggacccaat cactatttcg cttcaaacct tttctgattt
     5521 cctttcctcc gaaacaggaa tcaaaaaaga aaaaaatagt atgaagaaag attatcaaaa
     5581 accgatgctt attagcgaag agttcattcc gaacgaatat gtagctgcat gctataactt
     5641 taaagcacta tttcattgtc attatggaga aaacaataca aacaatcatg gaaaaccatg
     5701 cgctacaacc tatgtagata ttaatggtat ccatgctaca gggcacgaag ggactataga
     5761 aaaatggggt atacctattc tcaatattga ttggaatgga ttcgatttaa gtgacgcaaa
     5821 agtaggtgac gagattagag gcatcaagtg gactagctat gatacagtaa ataacactgg
     5881 agaatacaat catcaaggtt ggggtgaaat caaatctgct gttgaagaaa taccaggtcg
     5941 tcctaaccac tcttaagaca ttcccctatt tatgaaattc gcatcaaata acagtataga
     6001 cttggacctt aaaagtaaag tctatactgt aaacctctca aattagggtt ctaaaatatc
     6061 tatcttcgct gcgaatcaaa atttacgaat tatgcaaagc aatgaagacc ttgaaagatt
     6121 ctactttccc tatctttggg tctatcatcg taaaatatag acttggttgt atgccaatag
     6181 ttaaaaatca atcgaatttg ataatatctt tttgtgagat gccaattctg gtgccttata
     6241 aaaaggatat gctctaaatt aagtattaac ttttgttggg cttcaaaaag ggaagataat
     6301 ctatatattt tccatcgaga caaatttcgg taacatatac gaccacggaa gtaaatgaaa
     6361 tccaatacac tagactcaaa aacttttctt tgaaaaaaaa tcattatcct agtggaatcc
     6421 ctgcaagaca taaaccctgt ggaacgggca ttggtgaaca aagcgacggc aaaccgtact
     6481 ccgatcaatg ccactattga attgacaccg acgtgcaatt tccgttgtga tatgtgctat
     6541 atccgcatgg agaagtcaca agccgagaaa agaggaggat tacggagcat agaggaatgg
     6601 ctgcacattg ccgaccagct acaggaaata ggaacgctct tcatcttact gacaggaggc
     6661 gagcccctac tctatcctga tttcaaagaa ttatatatcc ggctgaaaga aaaaggattc
     6721 atcctcacca tcaatacaaa cgcgactttg atagatgacg aaacagtacg tctgtttcaa
     6781 cgtttgaaac cccggagggt gaatgtctcg ttatatggtg tgaccaacgg aacttatctc
     6841 aatctgtgcc acgcgacaaa cggtttcgac cgttgcctgg aaggactgaa acgattaaaa
     6901 gaatatggca tagataccaa actgaacctc accttgacac gacaaaatat aaaagaacac
     6961 cggcaaatgc tggaactagc tgacgaatgg gacttaccta tgctgaccaa cagttacatt
     7021 tcagtctatt cacggccggg atgcgccacc acgctacccc ttgatacgtg ccgccccgta
     7081 ccggatgaag tggcacatgc cgaggttgag gcactggaac ataaatatgg caaggaatac
     7141 acatcatacg ccactcatgt cctccagcaa ttggaacgtg gagaatctcc cgtacctgct
     7201 gaaggcatcg gacttgcctg ccgggcaggt aaaagttccg catggatcaa ctggcagggc
     7261 gtcatgactc cgtgcgtcga tatggaaaca ccagccgttt cgctactttc cacaaccgta
     7321 agcgatgcct ggaaacaaat agtaaccaaa tgcgaacaac ttccgttcca taaagaatgc
     7381 gcaggttgta ccttacgctc tatctgtgat gtctgctatg ccaatgcccg caatgaaaaa
     7441 gggcaatgcg gcggcatcgg ctacctttgc cgcattgcaa aaagtaaaaa gaaacaaatg
     7501 aaaggaagtc tataaagact tttctcataa atacatatac attccaagtt atggatcatc
     7561 ttcacgatgc caaccttttg gaacgggcat tggtggacaa agccaatcag agccgtgtcc
     7621 cgatcactac caacttcgag ctgactccca cctgtacgct caactgcgac atgtgcttca
     7681 tacgcaccga acgcagcgtg gtggaacggc acggaggttt atcgcctttg caacaatggc
     7741 tcgactgggc agaacaactt caagacatgg gtacactctt catccttctc accggaggtg
     7801 aaccgatgct ctatccacac ttcaaggagc tgtacacccg gctgcgcgaa atgggattca
     7861 tcctgactct caatacgaac ggcacactca tcgacaacga aatggtacgc atcttgcaga
     7921 cccacaagcc gcggcggata aacgtcaccc tgtatggaga cagcagagaa acttacggac
     7981 gcttgtgcca caatccgcaa ggatacaccc tgtgcatgga agccctgaaa cggttgaaaa
     8041 aggcagacat tgatgtgaaa ctgaacgtaa gtatcgtacg aaagaatgaa aaagattacg
     8101 acgagatcat ccgtctggcc cagcatctgg acattccggc agaagtaaac tcatacatgt
     8161 ttcctctctc acgccccgaa tgcggaagtc tgcgtaacat tctaactgaa agactggatg
     8221 ccgacgaggc ggcccgcatc gagatgcaat atatggagta caaaaaaggg aatgacatgg
     8281 cacgatacat gcacgacttg aaatatacgc ttgcccatgt ggaaggaaca cgagcctgct
     8341 ctttggagtg cagagctgcc aagagttcat gctggatcaa ctggcaaggc atcctcaccc
     8401 cctgtgtgat gctggatcaa ccggccgttg acctgaaaaa gattccgatg acaactgcat
     8461 ggcaacaact tttagaagaa gccaaggaac tggtatccca taccgaatgc gagggttgcc
     8521 accttcgtcc cgtatgcaac gtatgctatg ccgccgcaca ctgtgaaaaa acaatcaccg
     8581 gaagcatgga ctatctttgc cagatggcga aagccaaaga acggatcatt acgaattatc
     8641 cccccgtaat acattaaaaa ctgaagattg tgagactgaa tatcggcccg ctaacgattg
     8701 aattgtcagg agtgacagaa caggagattc ctgttaacag ccgtttgttt ctcgaccata
     8761 aacccgctac caaagaagcg gaccggtact atacattcta ttttgtcaac cgtctgcctt
     8821 tgccgtccaa cgactggcag atcacattcc aacgcaacga catcgtagtt ttccggaagg
     8881 aagaacaaga aacacgcctg ctggctgtag gaaacctgaa tgcctgctat gctctctatc
     8941 aggaaagaaa cgaaagagat gccaacatct atttcatcga aggtctgaaa agagaactgc
     9001 aaacagatac cctgttcatt tcctgcctgt gcctggaacg tcctttatct gtccagggat
     9061 gttacatact acattgtact tttctggatt atcgtgggca agccatctta ttcagtggtc
     9121 ctagcggcat tggcaaatcg acgcatgcca acctgtggtg ccggcatatt cccggcaccc
     9181 aggtactcaa tggcgaccgt gccctgctct gtccacttcc aaacggcgac tacgagataa
     9241 cgggatggcc tgtatgcggt tccagcggta tctgtcacaa tgaacgccgc ccgttggagg
     9301 ccattgtatt catcgaacag gcatctgata acaccatccg tccccagaca gccatgaagc
     9361 atttcaaagc tctctgctcg caggttacaa tcaactggtg gaatccaaag ctcaccggca
     9421 aagcactcga cgatctgcag gttttgacca gacagacaag catcagcacc tatgcgtgca
     9481 acatgaatcc ggaagcagcc ttcaccctgc acaggtatct gaccaaactg gaaattatcc
     9541 gataatgtga aatacgcccc attatgaaga ctgtcgatac gaaagaatat atatccatgc
     9601 tgcgtaccct cattgaggaa ggaaagcagg tgagcatgat catctcgggc agcagcatgg
     9661 ctccattcct gatccacgca agagaccaca tctacctgaa aagcccctcc ggtgaacttc
     9721 ggaaaggaga tatggtgttc tatcagcgaa gcaacggtga atatgtcatg caccgtattt
     9781 ataatgttaa aaatgaagaa tattatctta tcggtgacgc ccagactgtc atcgaaggtc
     9841 caattcaaag agaacagatt ttcgccatca ttatcaaggt gaagcgaaaa gggaaatgga
     9901 tagttccaga agatttccag tggaaattct tcgcccacat atggccgaac ataattcctt
     9961 tacgcaggac catcattaaa acatatcgtt ttttcaaaag atgaaaagaa ccaaagaatt
    10021 tatcaaacga aacatagccg gagaaatcgt actggttcct tccggacaga ccgcccgaga
    10081 gttcaacgga atggtcaccc tgaccgaaac cggagaattt atctgggagc atatcgaaga
    10141 agcagaaagc ttcaaccatc tagtactgtt gattctggag gaatacgaag tggataaaga
    10201 caccgcatcg caagatgccg caggatttat catgcaactg ctgcaagccg gcatgatccg
    10261 tcccacaggt ataaactggt aaacagtaat ctgttcagag gagttctata aattaaaata
    10321 ttgtagtaca gttgtttata tggttccaag agcgt
//
