LOCUS       c00243_gnlPro..        12775 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KLOCNCOL_275.
ACCESSION   c00243_gnlPro..
VERSION     c00243_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 23:54:23
            Original ID  :: gnl|Prokka|KLOCNCOL_275
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12775
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12775
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[9612:12604]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      9613..12604
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..12775
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12775
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             147..1616
                     /locus_tag="ctg243_1"
                     /transl_table=11
                     /translation="MGGAEYMKSIKKYETIINEALRSALEYDTPEGQINEFISFFGKHI
                     GSDRIYIFEDDEEHHVTNNTYEWCAEGITPQIEHLQGVNMEVIDWWYDTFDEGKSVIIS
                     DVEELKGVHQVSYNMLKYQNVCKVVVSPLRHKGQIKGFFGVDNPPAVDYNALTMFLDMI
                     GTMLIALLKIRNTFQKEQYNASMSSYSALSEIYLCMHLIDIKTGKYEQIKNVKHVEKEC
                     EELDQENFSKRVYTTMKYFCTEMYLSSVLEFVDLSTLDRRLMETNTIVHEFIGTVSGWC
                     RERFIKVDSDEKGRLWHVLYCVEVIDEQKRREKKLLYLSETDSMTGINNRGSGERKITE
                     FLEKKKGGLFCLLDCDKFKKINDTYGHAVGDTVLIKLAAVLQRACRENDIVMRLGGDEF
                     AMYLPGMPDKAQAESFFKRLFTQIDKISIPEMQGEKINVSLGASLCSDKDRATFDTLYR
                     EADAAMYESKKIVGNHAIIYSDLPQARQTPL"
     CDS             1768..1935
                     /locus_tag="ctg243_2"
                     /transl_table=11
                     /translation="VYVLKLVARDTIEEKIIHLQEKKAKLAEDIIEGKETAEHYLIREE
                     IIDLLSEKDK"
     CDS             2294..3019
                     /locus_tag="ctg243_3"
                     /transl_table=11
                     /translation="MIDNKRQELIHSQVMEILKENQLAFSNVARPKPTKASTATSASWS
                     KDMAPKASAATQGAWDSTNTPGGVSSLAKEKWNVQEIAALVTKALEASNVKVAFSNKPI
                     PAPTTISSSTQPAWKKDEDEAPRKPAAGTQGAWDVTDTPGGLSAETKKVWNLDAITALV
                     KKELTENLEFYNKPLPKPTTVSSSTQPAWKDDSEEYKPKESASAQGIWERGNKISASTQ
                     PAWKVDEIAALVTKALQNK"
     CDS             3214..4398
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 116.3; E-value: 4.7e-36)"
                     /gene_kind="transport"
                     /locus_tag="ctg243_4"
                     /sec_met_domain="MFS_1 (E-value: 6.8e-37, bitscore: 116.3,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQSKMTLKEWLPLLGITVSAFIFNTSEFMPIGLLTDIADSFHITE
                     AHAGVLITVYSWIVMLLSLPLMLLLNKIDFKRLLLGTIALFGIFQMLSAFSASYGMLMI
                     SRIGVACTHSVFWSIASPAAVSVVSEKFRSLALSMVVTGTSIAMILGLPLGRIIGLHMG
                     WNMAFFCVGIIAFITTAYLIFVFPKVPGGESFSIKQMPEIFKNKTLMGIFLVTFLFATS
                     YYTGYSYIEPFLQKVAGLSDNWVTTTLTIFGAAGLLGSFLFSHYYDKNKYLFVKLVMIS
                     VAAALLLLYPISKAHMAVVLLCAFWGMAVMAFNVTFQSEIITYAPAAASSVAMAIYSGI
                     YNLGIGSGTWIGGSICTHLSISYIGIAGGMIAVVAALLCIFVVIKYMKEFDRAA"
     CDS             4695..6284
                     /locus_tag="ctg243_5"
                     /transl_table=11
                     /translation="MSRIDEIKKRRTFAIISHPDAGKTTLTEKFLLYGGAINQAGSVKG
                     KATAKHAVSDWMDIEKERGISVTSSVLQFEYGGCCINILDTPGHQDFSEDTYRTLMAAD
                     SAVMVIDASKGVEAQTRKLFKVCAMRHIPVFTFINKMDREARDIFDLLDEIEKELGIPT
                     CPVNWPIGSGKQFAGVYDRKSQKIDLFEDTMKGTKMGTMKEIALDDPEISNYVTDEAKE
                     VLEEEIELLDGASAEFDQELVDAGELSPVFFGSVLMNFGVENFLNYFLKMTSSPLPRTS
                     DQGTIDPIEEKDFSAFVFKIQANMNKAHRDRIAFMRICSGEFEAGMDAFHVQGDKKVRL
                     SQPQQMMASERKMIDKAYAGDIIGIFDPGIFSIGDTITTSPKKFAYEGIPTFAPEHFAR
                     VRQVNTMKRKQFIKGINEIAQEGAIQIFQEFNTGMEEVIVGVVGTLQFDVLNYRLQHEY
                     NVEIRLEKLPYEYIRWIENTEIDLENLRGTSDMKKIKDLKGRPLLLFINSWSVGMTLER
                     NEGLVLSEFGRA"
     CDS             6560..8206
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg243_6"
                     /sec_met_domain="Radical_SAM (E-value: 1.4e-18, bitscore:
                     57.1, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEKEYRLKTLFWEATLRCNAFCEFCGSRCGEMSCNEISGEKIEK
                     VFEDIADAYNPGSIMINVTGGEPILRKDLFEVMAKASAMGFPWGMVSNGSLIDKCIIQK
                     MKQSGMKTISISLDGMEETHNRLRKIENGFQKTVQAIKDLKQAAFLNQIEVTTVVNHYN
                     IEQLEEMYSMIKSFGIDSWRVAVADSIGRAKENQKLLLGKREFQQYCTFLDRHRFDTEL
                     RIITSCSHYLGKNDNKYRANPFSCETGKSVASILANGDIFVCPNVERRKELIQGNVQKD
                     NFVEVWENKFEFFRSETRCQSKKCKTCKDWESCRGDSLHTWNFEKKEPSFCIKDYMEDI
                     FYSKELPMELIKKMKSQVKDRMIGIKISSKSQTDQCVYFSPNASEELFYYFHFGKKHPR
                     NMDELMAGLAGHVINDNIVLVEFIVPIELDTRSSDKAVFSNNSYNKLQEELKIMNKARE
                     NCDEELQLFSSELQLVGTIHSHPGNLRTIMSIPDMGLHKYLSEHIDTYKTTTILNAQKR
                     QIASYGDTEFCSADIIFLEAEQQIARWNLVK"
     CDS             8232..9152
                     /locus_tag="ctg243_7"
                     /transl_table=11
                     /translation="MEEYTQRLTESSWDNKEWICSICGRQNKEEFKYCPECGEKKPDHE
                     ETQTEITIKKLKRKGFENCEQLFRLLIHVEDEEGNLLGSYNMTLHGYATKQELLNLLED
                     YLGYKENHRAPKKYHLEIQDWPYHSLDSAYETKEDFHVCELYSAEWNAVRKEYGEKRTD
                     HEETWEEIRIKQKDYANCEQKYKVLVHLEDEEGNPLGNYNVMLCEYDTEKELIDLLEDY
                     WGYKKNIYKEYYLKVIDWPHNPGPSEWWPGSSLHVCEMEEREFRVIRKKYKEDDGPMPC
                     LYGCPNSRDIEEKKEVETKVEIVYF"
     CDS             complement(9613..10365)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74.8;
                     E-value: 2.7e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg243_8"
                     /sec_met_domain="Radical_SAM (E-value: 5.6e-32, bitscore:
                     100.7, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTECNKNAMALVHSTESFGSVDGPGVRFIVFLQGCPLRCQFCHNP
                     DTWKMTEENGAVWRSADELLNQALRYRTYWKNSGGITVSGGEPLLQIDFMLEFFKKAKE
                     KGIHTVIDTAGGPFTREEPFFSKFQELMKYTDLLLVDIKHIDTECHKTLTGRSNENILD
                     MIRYLSDIKKPIWIRHVLVPERSDKDEYLTRLADFIHSLDNVEKVEILPYHTMGIYKWK
                     ELGLEYPLEGIEPPTKERVENAKKILAI"
     CDS             complement(10352..12604)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg243_9"
                     /sec_met_domain="Gly_radical (E-value: 1.1e-42, bitscore:
                     134.2, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 2.6e-267, bitscore:
                     877.2, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLQKEQWQGFNGRIWREEINLREFIQDNYTPYDGDASFLEGPTEA
                     TDTLWGELQKLQKAEREKGGVLDMDTDIVSSLTSHKPGYISESLKEKEQIVGLQTDKPL
                     KRAFMPFGGIRTAEEACTTYGYTPNPEFHKIFTDYHKTHNQAVFDSYTPEMKKARHNKI
                     ITGLPDTYGRGRIVGDYRRVALYGIDLLVADKQKDFANCGDGTMTDDVIRLREEISMQI
                     KALKDMKVMAESYGYDISEPASNAKEAVQWTYFGYLAAIKTQNGAAMSIGRIATFLDIY
                     IKRDMDKGILTEKEAQELIDHMTMKFRMVKFGRIPAYNQLFSGDPVWATLEVGGLGQDG
                     RSMVTKTDYRFLHTLENMGPSPEPNLTVLYSERLPKAFRDYAAHISITTSSIQYENDDV
                     MRPVWGDDYSICCCVSATQTGKEMQFFGARANLAKCLLYAINGGVDEKTGQQVGPEYKP
                     ITSEYLDYDEVMHKYDIMMDWLAGLYVNTLNLIQYMHDKYYYEYALMALIDTNVRRTFA
                     TGIAGFSHVVDSLSAIKYAKVKTVRNEEGLVVDYETTGDFPKYGNDDDRADDIAVWLLQ
                     TFMKKLEKFHTYRDSEPTTSILTITSNVVYGKATGSLPDGRKAGEPLSPGANPSYGAEQ
                     NGLLASLNSVAKLPYEWALDGISNTQTINPDALGHSEEERINNLVNVMDGYFAQGAHHL
                     NVNVFGVEKLIDAMEHPEKEEYANFTIRVSGYAVKFISLTKEQQLDVIARTCHDRM"
ORIGIN
        1 aattatagta gtatttttta aattgctata gacacatctt atgataaaac agaggaattg
       61 aacaagaata ttcttaaaag attttctggc aggcgtacct aagaaaagat atatgtagat
      121 caagaaaaaa tatttacaaa agtatcatgg gaggggcgga atatatgaag tcaatcaaga
      181 aatacgaaac aattattaat gaggcactgc gttcagcact tgaatacgat actcccgagg
      241 gacaaattaa tgaatttatc agtttttttg gaaaacatat cgggtctgac agaatttata
      301 tttttgagga tgacgaggag catcatgtaa caaataatac ttatgaatgg tgtgcagaag
      361 gaattactcc gcagattgag catttgcagg gtgtgaatat ggaagtaatt gattggtggt
      421 atgatacttt tgatgaggga aaaagtgtta ttatttctga tgttgaagaa ttaaaaggag
      481 tacatcaggt atcttacaat atgcttaagt accagaatgt ttgtaaagta gttgtcagcc
      541 cattacgcca taaagggcag ataaagggat ttttcggtgt agataatcca ccggctgtag
      601 attacaatgc attaacaatg tttttagata tgatcggaac catgctgatt gctcttttaa
      661 aaataagaaa tacatttcaa aaagagcaat ataacgcaag tatgagcagc tactcagcac
      721 tttctgagat ttatttatgt atgcatttaa ttgatataaa aacaggaaag tatgagcaga
      781 taaaaaatgt aaaacatgta gaaaaagaat gtgaagagct tgatcaggag aatttttcaa
      841 aaagagtata tacaactatg aaatacttct gtacagaaat gtatttatca agtgtactgg
      901 agtttgtgga cttatcaaca ttagacagac gattaatgga aacaaacaca atcgttcatg
      961 aatttatagg tacagtttcc ggatggtgcc gcgagcgctt tatcaaagta gatagcgatg
     1021 aaaaaggccg tctgtggcat gttctttact gtgtggaagt gattgacgaa cagaaacgcc
     1081 gggagaaaaa gctgctgtat ctttctgaaa cagattccat gaccggtatt aataaccgtg
     1141 gaagcgggga gcgaaagatt acagaattcc tcgaaaaaaa gaaaggtggc ctgttctgcc
     1201 ttttagactg tgataaattc aaaaaaatca atgacacata tggacatgcc gttggagata
     1261 ccgttctcat taagcttgca gcagtccttc agcgagcctg ccgtgagaat gatattgtca
     1321 tgcggcttgg aggtgatgaa tttgcgatgt atcttccagg aatgccagat aaagcacaag
     1381 cggaatcatt tttcaaacgt ttatttacgc aaatagataa gatttccata ccggaaatgc
     1441 agggagagaa aattaatgtg agtctgggag cttctttatg ttcggataaa gatagagcaa
     1501 cttttgatac gctatatcgt gaggcggatg cggcaatgta tgaaagtaag aaaattgtgg
     1561 ggaatcatgc aataatatat tctgatttgc cacaggcaag gcagacgcca ctgtagaaga
     1621 attatcattt ctttaaagaa caataatttt gctatcacag tgaaaaagtt cagagtaaaa
     1681 gtatgagaaa tacttctgtt ctcggtggaa tgtagcagca cagaattagg ctacagacag
     1741 aacacatcgt atcgggcaaa aaatgtagtg tatgtcctca aattggttgc cagagacacg
     1801 atagaagaaa aaattattca tttgcaggaa aagaaggcaa aactggcaga ggatattata
     1861 gaaggcaagg agacagcaga acattattta atccgagagg aaatcataga tttgttatca
     1921 gaaaaagaca aataatggaa atatactgta agttcgcaat aagtaatact atcaaagaaa
     1981 ctgctgtgca aagagtcaat atatttcagt aataagacag caattttcat atatcctctc
     2041 tttagattag tgctataata aaataaatat gactattcag aaataattca tggaatcgca
     2101 tttgcgatgc ttattttttg ctttgaatag ccgcagttta tataacataa cacaaccgtg
     2161 ggacaacacg ggggtagctc gcttatgctt agcacaacgg tgctatcgaa cgagaaccga
     2221 cctctatagg tggggaggat gtcaccataa ccagaaaacc aaagtataca tattgggaaa
     2281 ggggtagaaa gacatgatag ataacaagag acaggagctg attcatagcc aggtaatgga
     2341 gattctcaaa gagaaccagt tagcattttc taatgttgca cgtccaaagc caacaaaagc
     2401 ttctacagca acttcagcat cctggtcaaa agacatggct ccgaaagcat ctgcagcaac
     2461 acagggagca tgggacagca caaatacacc gggcggtgtt tcttctttag caaaggagaa
     2521 atggaatgta caggaaatcg cagcacttgt aacaaaggca ttagaagcca gcaacgtaaa
     2581 agttgcattt tctaataagc caattcctgc accaacaaca atttccagtt ctacacagcc
     2641 agcatggaag aaagacgaag acgaagctcc tcgtaaaccg gcagcaggta cacagggcgc
     2701 atgggatgtg acagatacac caggtggact ttctgctgag acaaagaaag tatggaatct
     2761 tgatgcaatc acagctctgg taaagaaaga attaacagag aaccttgagt tctataacaa
     2821 accactgcca aagccaacaa cagtatccag ttccacacag ccagcatgga aagatgacag
     2881 cgaagagtat aaaccaaaag aatctgcatc tgctcaggga atctgggaga gaggcaataa
     2941 gatttctgca tctacacagc cagcgtggaa ggtggatgaa atcgctgctt tggtaacaaa
     3001 ggctctgcag aataaataat atttactaca ggcaagggga gatgtcctct gaaagataaa
     3061 taaagcatat ttgtgacttt agtcgctgtg gtttgaatgt tcgcttggac gcgcgaatgt
     3121 tcaaaccttg ttccgaggcc acaaatatgc tttatttatc tttcagaaga ctgtctttgg
     3181 ctgcggcaaa ttactattta gaaaggaatt attatgcaaa gtaaaatgac acttaaagaa
     3241 tggctgccac tgcttggtat cacagtctca gcattcatat ttaacacatc agagtttatg
     3301 ccgattggtt tgttgacaga tattgccgac agctttcata ttacagaggc acatgcgggg
     3361 gtactgatta cagtatattc atggatcgtt atgttactgt ctctgccgtt gatgcttcta
     3421 ttgaataaga ttgattttaa aagacttttg ttaggaacga ttgcactttt tggaatcttc
     3481 cagatgctgt ccgctttttc tgcttcatat ggaatgttaa tgatatcacg tattggcgta
     3541 gcgtgtacac attcagtatt ctggtcgatc gcatcaccgg cagcagtcag tgttgtgtca
     3601 gaaaagtttc gttcacttgc acttagtatg gtagtaaccg gaacctcaat tgcgatgatt
     3661 cttggacttc cgctaggaag aattatcgga cttcatatgg gctggaatat ggcatttttc
     3721 tgtgtaggaa tcattgcttt tatcacaacc gcttacctga tttttgtatt cccgaaagtg
     3781 ccgggcggag agtctttctc cataaaacag atgccggaaa tctttaaaaa taaaacgctg
     3841 atgggaattt ttcttgttac ctttttattt gccacatcgt attatacggg atatagttat
     3901 attgaaccat tcttacagaa ggtggctggt ctttctgata actgggttac aacaacactt
     3961 actatatttg gtgcagcagg tcttttggga agttttttat tttcccatta ttatgacaag
     4021 aataaatatc ttttcgtaaa actggtaatg atcagtgtgg cggcagcatt acttttatta
     4081 tatccgatat caaaagcaca tatggcggtt gttttattat gtgcattctg gggtatggca
     4141 gttatggcat ttaacgtgac atttcaatca gaaattatta cttatgcacc ggcagcggct
     4201 tcctctgtag caatggcaat ctattccgga atctataatc ttggaatcgg aagcgggaca
     4261 tggattggag gaagtatttg tacccatctg tccatttcct atatcggaat tgctggtggc
     4321 atgatagcag tagtggcggc attgttatgc atatttgttg tgataaagta tatgaaggaa
     4381 tttgatagag cagcttgatt ttaaagcggg tattgatact cgcttttttt gcttaaaata
     4441 gaaaaattac gggacgtaga aggatgtaat ctgaaatatg taacaaaaat aaaagatata
     4501 cttgcgaaaa tgatggtttt atacgataat aggtactgtt tgacctgaaa tagaaaaatc
     4561 aggcaacata gagtaaagag agattgaaaa tagataattg gaaaattaaa tggagcttcc
     4621 gagtaattca attgcggaat gcttcaggat aataaaagtt atcgtatagg agcataaaaa
     4681 acaaggagag aaaaatgagc agaatagatg aaattaaaaa acgacgtacc tttgcaatta
     4741 tttcgcaccc ggatgccggt aagactacat taacagagaa gttcctttta tatggaggtg
     4801 caatcaacca ggctggttcc gttaaaggaa aagcaaccgc aaaacatgcg gtatctgact
     4861 ggatggatat tgagaaggag agaggtattt ccgtaacttc ttccgtatta cagtttgagt
     4921 acggcggatg ctgtatcaac attctggata ctcctggaca tcaggacttc tcagaggata
     4981 cttaccgtac attaatggca gcggattctg ccgttatggt aattgatgca tcgaaaggtg
     5041 tagaggcaca gacaagaaag ctttttaaag tttgtgccat gcgtcatatt ccagtattta
     5101 catttatcaa taaaatggac cgtgaggcaa gggatatttt tgatctctta gatgaaatcg
     5161 aaaaagaact tggaatccca acttgtccgg taaactggcc aatcggttcc ggtaaacagt
     5221 ttgcaggcgt ttacgacaga aaaagccaga aaatcgattt atttgaagac acaatgaagg
     5281 gtacaaagat gggaacgatg aaagaaatcg ccctcgatga cccggaaatc agcaactatg
     5341 tcacagacga agcaaaagaa gtattagagg aagaaattga gcttttagat ggggccagtg
     5401 cagaatttga tcaggaatta gttgatgccg gagaactctc tccagtattc tttggttctg
     5461 tcctcatgaa ctttggcgta gagaatttct taaattactt cctgaaaatg acttcctccc
     5521 cactgccaag aacttctgat cagggaacaa tcgacccaat tgaggaaaaa gatttttctg
     5581 catttgtatt taagattcag gcaaatatga acaaagctca ccgtgaccga atcgccttta
     5641 tgagaatctg ttccggcgaa tttgaggcgg gaatggatgc tttccatgta cagggagaca
     5701 aaaaggtacg tctttctcag ccacagcaga tgatggcaag tgagagaaag atgattgata
     5761 aagcctacgc cggagacatt atcggaatct ttgacccagg cattttctct atcggagata
     5821 ccattacaac ttcaccaaag aaatttgctt acgaaggaat ccctaccttt gcgccagaac
     5881 atttcgcaag agtgcgtcag gtaaatacga tgaaacgtaa acagttcatc aagggaatca
     5941 acgaaatcgc acaggaaggt gctatccaga ttttccagga atttaatact ggaatggaag
     6001 aagtaatcgt aggtgtagta ggaacattgc agtttgatgt attaaattac cgcctgcagc
     6061 acgaatacaa cgtagaaatc cgccttgaaa aacttccata tgaatatatc cgctggattg
     6121 aaaatacaga gattgacctt gaaaatcttc gtggaacatc ggatatgaag aagattaagg
     6181 atttgaaagg tcgtccattg ttactgttta tcaatagctg gagtgtggga atgactctgg
     6241 agagaaatga aggacttgta ctctcggaat tcggaagagc ctagagcgtg tttgaaaaat
     6301 cattccagca atctgcacac cccaatttac ggtatatttt gtcttcattc ggttgccgta
     6361 gcccgctacg ccgccttcat tcaggcgaaa tctcccgcaa attgtgatgc acatcttgca
     6421 gaaagcattt ttcaaacacg ctctagaatt tctgatttgt tgaattggca aaactgacgc
     6481 ccacagagaa tattgtattc cctgtaggcg tctttcttgc ctgcggcaaa tcaaaatttt
     6541 taccaaaaag gagaggtata tgaaagagaa agaatatcgt ttaaaaacac tattttggga
     6601 ggcaacatta cggtgcaatg ccttttgcga attttgcgga agccgttgtg gggaaatgag
     6661 ctgtaatgag atttcaggtg agaaaattga aaaagtgttt gaggatattg cggatgcata
     6721 taatccagga agcattatga ttaatgtaac tggaggggaa ccgattttga gaaaagattt
     6781 gtttgaagtg atggcaaaag catctgctat gggatttccc tggggaatgg tttctaatgg
     6841 ttcgcttatt gataaatgca ttatacagaa aatgaagcaa agtggaatga agacaatatc
     6901 tataagttta gatgggatgg aagaaacaca taatcggtta agaaagatag agaatggatt
     6961 tcagaaaact gttcaggcta taaaagattt aaagcaagct gcgtttttga atcagataga
     7021 ggttacgaca gtggtaaatc attataatat tgaacaatta gaagaaatgt attctatgat
     7081 aaagtcattc gggattgatt cctggagagt tgcagtcgca gatagcatag gaagagccaa
     7141 agaaaaccag aaattacttt tgggaaaaag agagtttcag caatattgca cctttcttga
     7201 ccggcacaga tttgatacag aattgcggat aattactagc tgtagtcatt atcttgggaa
     7261 aaatgataat aaatatagag caaatccttt ttcttgtgaa acgggcaaaa gtgtagcatc
     7321 aatattagcg aatggagata tttttgtttg cccgaatgtg gagagaagga aagaattaat
     7381 tcagggaaat gtacagaaag ataattttgt agaggtatgg gaaaataaat ttgaattttt
     7441 ccgttcagaa acaagatgtc aaagtaagaa atgtaaaact tgtaaagatt gggaatcctg
     7501 tcgtggagat agtttgcata catggaattt tgagaaaaaa gaaccttctt tttgtataaa
     7561 agattatatg gaggatattt tttattcaaa agagcttccg atggaattga ttaaaaaaat
     7621 gaaaagtcag gtcaaagaca gaatgatagg aataaaaatc agttcgaaat cacaaacaga
     7681 tcaatgtgtg tatttttctc caaatgcatc cgaggaactt ttttattatt ttcattttgg
     7741 aaaaaagcat ccaagaaata tggatgaact tatggcggga ttggcaggac atgttataaa
     7801 tgataatata gtattagtag aatttattgt tccgatagaa ttagatacga gatcttcgga
     7861 taaagcagta ttttctaata attcttataa taagcttcag gaagaattaa aaataatgaa
     7921 caaagcaaga gaaaattgtg atgaggaact tcagcttttt tcttcagaat tacagttagt
     7981 aggaacaata catagtcatc cgggtaattt aaggacgata atgagtattc cagatatggg
     8041 cctgcataaa tatttaagcg agcatataga cacatacaaa acgaccacta ttttaaatgc
     8101 tcaaaagcga cagattgctt cttatgggga cacggaattt tgttcagccg atattatttt
     8161 tttagaggcc gaacaacaaa tagcaagatg gaatttggta aaatagtatt ataaagtcag
     8221 ggagtgcaat aatggaagaa tatacacaaa gattaacgga atctagctgg gataataagg
     8281 aatggatatg tagtatttgt ggaagacaaa acaaagaaga gtttaaatat tgtcctgaat
     8341 gcggggagaa aaaaccagat cacgaagaaa cacaaacaga gataactata aagaaattaa
     8401 aacgaaaagg ctttgaaaac tgtgaacaat tgtttagact tcttattcat gtcgaagatg
     8461 aggagggtaa tctattagga agttataaca tgacgctgca cggatatgcc acaaaacagg
     8521 aattgctaaa tttgttagag gattatctgg gatataaaga aaatcatcgt gcccctaaaa
     8581 aatatcattt agagatacaa gattggccat atcattcttt agatagtgca tatgagacaa
     8641 aagaagattt ccatgtatgt gagctctaca gtgctgagtg gaatgctgtc agaaaagaat
     8701 atggtgagaa aagaacagac catgaagaaa catgggaaga aataagaata aaacaaaaag
     8761 actatgcaaa ctgcgaacaa aaatataaag tgcttgttca tttagaagat gaagaaggca
     8821 atccactggg aaactataat gtaatgctgt gtgaatatga tacggaaaaa gagttaatag
     8881 atttattaga agattattgg ggatataaaa agaatatata taaagagtat tatctaaaag
     8941 ttatagattg gccacataat cctggtccaa gtgagtggtg gccgggtagt agtttacatg
     9001 tatgtgaaat ggaagagaga gaatttcgtg ttatcaggaa aaaatataaa gaagacgatg
     9061 gtccaatgcc ttgcctttat ggttgtccga attcaagaga tatagaagaa aagaaagaag
     9121 tggaaacaaa agtagagatt gtttatttct gatttgtagt gctaaacaga cgccgttgtt
     9181 tagggcaatg tagccggctt tttagaagtg tttagataag aaacataaaa caatagccta
     9241 ttttgttccg ttgtgctaaa tgctccattt tgcccagtaa agcaggaact tggcctcaaa
     9301 acctccactg gagctttttt cgatctgcta aggcaggaga agggagtccc aagttcctat
     9361 ggtcaaaatt ccgcagcaca aagtcgcaaa ataggctatg ttttatgttt ctttttccta
     9421 tattctttgt aaaatccgga aaaaaatttt tgtaacgtct gtttctctaa atcttgcaaa
     9481 aaatcctgca aattaatgga acaaaataca accttagaag aatccctctg ttagaagtca
     9541 tcgatgcaat ccgaccataa atatctccac agctgcgttt gtcatcaact ttacaaatca
     9601 gaaattgata gatcagatag caagaatctt cttagcgttc tccactcgtt cttttgttgg
     9661 tggctcaatt ccctccagtg gatactctaa tccaagttct ttccatttat aaattcccat
     9721 cgtatgataa ggcaggattt ccaccttttc cacattatca agagagtgaa tgaaatcagc
     9781 taatctagtc agatattcat ctttatcgct tcgttccgga acaaggacat gacgaatcca
     9841 aattggtttt ttgatatcag aaagatagcg aatcatgtcg agaatatttt cgttgcttcg
     9901 accagttaaa gtcttgtgac attcagtatc aatatgtttg atatccacta ataacaggtc
     9961 tgtatatttc atcaattcct gaaatttaga aaagaaaggt tcctctcttg taaaaggtcc
    10021 tccagcagta tcaataacag tgtggattcc tttttctttt gcctttttaa aaaactctag
    10081 cataaaatca atctgtaaaa gaggctcacc accacttacg gtaataccgc cgctattttt
    10141 ccagtaagta cgataacgga gtgcctgatt taacagctca tccgcacttc tccacaccgc
    10201 accattttcc tctgtcatct tccatgtatc tggattgtga cagaactgac atcgcaaagg
    10261 acaaccctgt aaaaaaacaa taaaacgaac tcccggccca tccaccgaac caaaactctc
    10321 cgtagaatga acaagagcca tcgcattttt attacattct gtcatggcat gttctggcaa
    10381 ttacatctaa ctgctgttct tttgtcagag agatgaattt aactgcataa cctgaaacac
    10441 ggatcgtaaa gtttgcgtat tcttcttttt ccggatgttc catagcatca atcagtttct
    10501 caacaccaaa tacatttacg tttaggtggt gagcaccctg tgcgaagtag ccgtccataa
    10561 catttactaa gttattgata cgttcttctt cggaatgacc gagtgcatca gggttgattg
    10621 tctgtgtatt ggaaatacca tctaatgccc attcgtaagg aagttttgct acagagttta
    10681 aggaagctaa aagtccgttc tgctcagcac cataacttgg gtttgctcct ggggaaagag
    10741 gttctccggc ctttcttccg tctggaaggg aaccagttgc cttaccatat actacgtttg
    10801 atgtgatagt aaggatggaa gttgtaggtt cagaatcacg gtaagtatgg aatttttcaa
    10861 gcttcttcat aaatgtctga agtaaccata cagcgatatc atcagcgcgg tcatcatcat
    10921 ttccgtattt agggaagtcg ccagttgtct cataatcaac aacaagtcct tcttcattgc
    10981 ggactgtttt tactttggca tatttaatcg cacttaagga atctactaca tgtgagaatc
    11041 ctgcgatacc tgtagcgaat gtacgacgta catttgtatc gattaaggcc atcaaagcat
    11101 attcatagta atatttgtca tgcatgtact ggatgagatt taatgtattt acatataaac
    11161 ctgctaacca gtccatcatg atatcatatt tgtgcattac ttcatcatag tcaagatatt
    11221 cggaagtaat cggtttatat tccggtccaa cctgctgtcc ggtcttttca tccacaccac
    11281 cattgatagc gtaaaggaga cattttgcaa ggttagcgcg agcaccgaag aactgcattt
    11341 ccttaccagt ctgtgtagca gaaacacagc agcagatgga gtaatcatcg ccccatactg
    11401 gacgcattac atcatcattt tcatactgga ttgaacttgt tgtaatagaa atatgagctg
    11461 cgtaatctct aaatgctttt ggaagacgct cagagtaaag tactgtgagg tttggctctg
    11521 gggatggtcc catattttct aatgtgtgga ggaaacggta gtcagttttt gtaaccatgg
    11581 aacgaccgtc ctgtccaagt ccgccaactt caagtgttgc ccatacaggg tcaccggaga
    11641 agagctggtt gtaagctggg atacgtccga acttaaccat acggaacttc atagtcatat
    11701 ggtcgattaa ttcctgcgct tctttctctg taaggattcc cttatccata tcacgtttga
    11761 tataaatgtc aaggaaagta gcgatacgtc cgatactcat agcagcaccg ttctgtgtct
    11821 tgattgctgc aaggtatccg aaatacgtcc attgaacagc ttcctttgcg ttagaagcag
    11881 gttcggaaat atcatagcca tagctttcag ccataacttt catatctttt aatgctttaa
    11941 tctgcatgga gatttcttct cttaaacgga taacgtcatc tgtcattgtt ccgtcaccgc
    12001 agtttgcgaa atctttttgc ttgtcagcaa ctaacaggtc aataccgtaa agagctacac
    12061 gacggtagtc accaacgata cgtccacgtc cgtaagtatc tggaagacca gtaatgatct
    12121 tattgtgacg agctttcttc atttcaggag tataagaatc aaatactgcc tggttatgtg
    12181 tcttatgata atctgtaaaa atcttgtgga attctggatt tggtgtgtaa ccataagttg
    12241 tacaagcttc ttcagcagta cggataccac caaatggcat aaatgcacgt tttaaaggtt
    12301 tatctgtctg aagacctacg atctgttctt tctcttttaa agactcagaa atgtaacccg
    12361 gtttatggga agtaaggctt gatacgatat cagtatccat atcaagaaca ccaccctttt
    12421 cacgctctgc tttctgcagc ttctgcagtt cgccccacag tgtgtcagta gcttcggtag
    12481 gaccttcgag gaaagaagca tctccatcat atggagtgta gttatcctgg atgaactctc
    12541 ttaaattaat ttcttctctc cagattcgtc cattaaatcc ctgccattgt tctttttgta
    12601 acatcttaat tgacctccct gtttgttaaa aaaatcctta agtcaaggtt ttgaaatatg
    12661 tttgctaaaa aatcaacaaa attgttcaga tgatttacta tgattagttt taacttattt
    12721 aagttttaat catctaacaa cattattaac atgatttttg gcaatcgtca aacaa
//
