LOCUS       gnlProkkaKFPFDFKC_39    9334 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KFPFDFKC_39.
ACCESSION   gnlProkkaKFPFDFKC_39
VERSION     gnlProkkaKFPFDFKC_39
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 01:42:31
            Original ID  :: gnl|Prokka|KFPFDFKC_39
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 9798
            Orig. end    :: 19132
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9334
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[5000:9334]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..9334
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..9334
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9334
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(811..2004)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_11"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.6e-24,
                     bitscore: 77.0, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTNIAIGTQENNHMLSVCIITKNEEHNLARCLKSFQNTGFELVV
                     VDTGSTDQTKKIAAEYTENIYDFPWCDDFSAAKNFAVSKATHPYVMVIDSDEYLQKIDL
                     SRLEKMIVEHPGEVGRIQRINIISGKDGKQENKEWINRIFAKESFHYTGRIHEQVTAYD
                     EKEYRTYEAPVLIGHTGYDLPKKEKKAKALRNIRLLEQELKNSGWDAKVHATQLEQNLS
                     KQDTDAEQKSEIADAKKEQQIPYLLYQLGKSYYMAEDYDEACFWFAHGLSYDLEPKLEY
                     VIDMVETYGYALINSGRAGEALFFENIYEEFGNSADFQFLMGLIYMNNAMFDAAVGEFL
                     KAVRHRDCRMAGVNSYAAYYNVGVIYECLGKISDAKYYYQKCGGYEPAKKRLRLINS"
     CDS             complement(2007..3719)
                     /locus_tag="ctg39_12"
                     /transl_table=11
                     /translation="MSGNIAIGIQDFSTIIQGNYFYIDKTPFIKEWWDCGDSATLITRP
                     RRFGKTLTMSMVEQFFSIDYAGRSDLFEHLAIWKEEKYRELQGTYPVISLSFARIKERD
                     YEKTKQKMCEVLRNIYIKFCYIKDSEKLTDADRAYYERMLEENIKETDATSSLYQLSDF
                     LYRYYGKKVIILLDEYDTPMQEAFVDGYWDELVAFTRSLFNSTFKTNPALERGIMTGIT
                     RVSKESVFSDLNNLKIVTTTSNEYASVFGFTEKEVFDALEQYGLEKEKKEVKRWYDGFI
                     FGEHKDIYNPWSILNYLDTQLYKTFWANTSANSLVGKLIQEGNRTIKEKFEKLLCGECI
                     WSEIEEQIVYNQLNGNEKAVWSLLLASGYLKVLSYETYQDIEEGKMPKYQLALTNLEVK
                     LMFQGMVHDWFAPVQPDYNDFVRAMLLGDVDAMNEYMNRIVIQTFSYFDTGERASGAEP
                     ERFYHGFILGLLVDLRDRYYLKSNRESGFGRYDVMLEPKNSKECKAVILEFKVRNPRKE
                     KSIQETVLSALKQICEKKYDADLLDKGIRKEQIYHYGFAFEGKKVLIGTDREE"
     CDS             3840..4853
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_13"
                     /sec_met_domain="Glycos_transf_2 (E-value: 6e-34, bitscore:
                     107.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVSVIIPCFNATKYLPKCFMSLVQQTIGIDQIELIFVDDASTD
                     EDATWNMLQEFERAYPESIMILKLEENMRQGGARNVALQYATGEYIAFVDADDFVAENF
                     LLETYEKAKESDADIIQFEYFYYTDRLGAVDSGRNIMPEVIEISSVNDRKEFLISEKIT
                     YGCWNKLYRHDLLKTAHTAYAEHVIYEEPLFVYPLLYFANKIVILNDAYYYYRQNDSGT
                     MRNDMRQEETLKMHADVQLAVWNFMKNTPFFQEYYDEIKLYFLHTYLYETLYFAKLRDF
                     KPSYSFYKELEKTVFTEVPDYSQSVYSALIPKQLELYRMIEEGMTEEKFGGYCERL"
     CDS             complement(5001..6209)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 206.2;
                     E-value: 1e-62)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_14"
                     /sec_met_domain="CTP_transf_like (E-value: 1.7e-09,
                     bitscore: 28.4, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 2.4e-117, bitscore:
                     381.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 5.1e-66, bitscore:
                     212.9, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAGVLSDTAMIRYNRFPTVSFEERKKMLEQIPEVDEVVVQDEVM
                     YGSILERIKPDYVIHGDNWLNDPMEVIRDNVIENLKKWGGQLIEIPYTYNEQVRNIEAV
                     MRERTAMPEYRRKRLRQLLQLCPIVKTLEVHSGLTGLIAEKTVVANNGEIDQFDAMWLS
                     SLCDSTAKGKPDIELVDMSSRLRTVDDVLEVTTKPIILDGDTGGMIEHFVYNVRTLERV
                     GVSAVIIEDKTGLKKNSLFGTEVEQTQDSIENFTAKIRAGKRAQRTKDFMIIARIESLI
                     LEKGLEDALVRAFAYVDAGADGIMIHSRKKTPDEIFAFCDRFREKDKITPLVVVPTSYN
                     ETYESELQQHGINIVIYANQLTRSAFPAMQQTATDILRYHRAKEVDDRLMSIKDIITLV
                     DEV"
     CDS             complement(6206..6295)
                     /locus_tag="ctg39_15"
                     /transl_table=11
                     /translation="MKKVYACFCTDVIHEGHLNIIREAKNMEN"
     CDS             complement(6292..7425)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 46.8;
                     E-value: 3.1e-14)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_16"
                     /sec_met_domain="TPP_enzyme_N (E-value: 2.2e-22, bitscore:
                     69.8, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.6e-15, bitscore:
                     47.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVTDFVEQIKKIGIKTLAGVPDSALKSFCDYINGTGKNEFEHYV
                     PVNEGAAVGIAIGSYLATGVPACVYMQNSGLGNIVNPITSLANKDVYGIPMLLLVGWRG
                     EPGTKDEPQHKYMGKITEDLLRVLEIEYIVLEKELSMQEIMRSFERAAQVLKEGKQFAF
                     VLKRDFLQNNNSSDYKNNNSLVREDAIAAIIKMLDESDVVISTTGKISREVYEQSDRIK
                     GSHAQDFLTVGGMGHASMIALGMAHKLEKKRVYCLDGDGAVLMHMGSMAYIAKQKPQNL
                     IHICLNNDAHESVGGMPTGCVGLSYADIAGTVGYERVYCVDKQQDLTKVLSDIKKKRNL
                     TFIEIKVAMQSRADLGRPKETAEENKNNFMKYHGVGL"
     CDS             complement(7419..7847)
                     /locus_tag="ctg39_17"
                     /transl_table=11
                     /translation="MRDILGSSDCFICEADLYVPDDTIFLRQYSTSCYFGKMIEGYSSD
                     WVFDVQNGNITRVGKGGTDTYNMAGISYWKRSDALIIKKAIEASYKKPGHEKLFWDEIV
                     DQELKRLKVQVEEISPESVIEVDTLEELSQLDSRYKTC"
     CDS             complement(7844..8131)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_18"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.4e-13, bitscore:
                     41.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKEKDEIAILMAAGLGTRMRPLTEQIPKPLVPVMGTPLIETVIC
                     ALERRGIKRIYVVVGYLKEQFSYLLEKYDNLEIVENKEYLKKTIFRHCMQ"
     CDS             complement(8150..9334)
                     /NRPS_PKS="Domain: Aminotran_5 (45-312). E-value: 5e-39.
                     Score: 126.1. Matches aSDomain:
                     nrpspksdomains_ctg39_19_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 84.7; E-value:
                     1e-25)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_19"
                     /sec_met_domain="Aminotran_5 (E-value: 6.4e-38, bitscore:
                     120.9, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKERKYVIINFLIIIQERTMKRNILLNPGPATTTDTVKQAQVVP
                     DICPREQEFVEIMKQIRKDLVKIVHGDEQDDTSVLFCGSGTISMDVCLNSLLPEEKKIL
                     IINNGAYSSRAVEICEYYGMPFINLEFPIDERPSLELIEQVLKENNDIALVYTTHNETG
                     TGILNPVREIGALVHRYGAVFVVDTTSTYAMRPIDIKKDNIDFCMASAQKGLMAMTGVS
                     FVIGNKSIIERSKDYPKRSYYCNLYLQYDYFEKHGEMHFTPPVQTVYAMRQAIAEYFAE
                     GEQEKWKRHTRVYDALYSGLERLGFQNVIKKEWQAGLVAAVKYPDDPNWSFSAIHDFCY
                     ERGFTIYPGKINNTETFRLCALGAIDETDIEDFFEIFEEGLKQMGVSLPVYYQK"
     aSDomain        complement(8399..9199)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg39_19_Aminotran_5.1"
                     /evalue="5.00E-39"
                     /label="ctg39_19_Aminotran_5.1"
                     /locus_tag="ctg39_19"
                     /protein_end="312"
                     /protein_start="45"
                     /score="126.1"
                     /tool="antismash"
                     /translation="DICPREQEFVEIMKQIRKDLVKIVHGDEQDDTSVLFCGSGTISMD
                     VCLNSLLPEEKKILIINNGAYSSRAVEICEYYGMPFINLEFPIDERPSLELIEQVLKEN
                     NDIALVYTTHNETGTGILNPVREIGALVHRYGAVFVVDTTSTYAMRPIDIKKDNIDFCM
                     ASAQKGLMAMTGVSFVIGNKSIIERSKDYPKRSYYCNLYLQYDYFEKHGEMHFTPPVQT
                     VYAMRQAIAEYFAEGEQEKWKRHTRVYDALYSGLERLGFQNVIKK"
ORIGIN
        1 aggcatacca tatgacacac acagactttg aacttcctct tccgtaaacc cggtaaattc
       61 agcgagttcc ctttgattgg tcatggaata ttcatcaaac atattgagag ctgaatgctc
      121 gccatacttt ttaatcggca gtattcccgt catataagcc aacgcaatat atggcttatc
      181 tttcatccac aggcacaaga aatccagata ttttttctgt gcttcatcat cccccggata
      241 ctttcgaaat atgcaatccc actcgtcgat aatgatgata aatttctgtt ttttctgact
      301 atagatgttc tctaatacat caataagatc ttcccggtca aaacagtcta catctccgta
      361 ttcccgcctg atatcccata aaagtctctt ttgcatataa tcgatcattg catccaccga
      421 ctgcgcccgg ttaagaaagt caagcatgtt gacatgaagg acattatatt tattcagatt
      481 tgcctcaaaa ctttcatcct gtgcaatctt ataatccgca aacatgcttt tcgaatcaca
      541 tcccttgcta taataagcta caagcatatt tgcagtcata gattttccaa aacggcgagg
      601 tctgcttacg catatattct gatgttcggt attcagattc tgattcattt cagaaatcag
      661 catggtttta tccacatata tcttggaatt aagtgctttc tgaaattctt catttcccgg
      721 atttaaatat attcccattc taatctccat tctgcatttg aaaaattata tttttcactc
      781 tgtttctcca ataagctgac tataataaat ttaactgttt atcaatctta aacgtttttt
      841 tgccggctca taaccaccgc acttctgata ataatacttt gcatcactga ttttccccag
      901 gcattcataa ataactccaa cattataata agctgcatag gaatttactc ccgccatcct
      961 gcagtcccgg tgccttaccg ccttaaggaa ctctccaact gctgcatcaa acatagcgtt
     1021 gttcatatag atgagcccca tcagaaattg aaagtccgcg ctatttccaa attcttcgta
     1081 aatgttttca aagaaaagtg cttccccggc gcgtccgctg ttgatcaggg catagccgta
     1141 ggtttccacc atatcgatca catactctaa ctttggttca aggtcatagc ttagaccatg
     1201 ggcaaaccag aagcatgcct cgtcataatc ttctgccatg taatagcttt ttccaagctg
     1261 gtataataga tacgggatct gctgctcttt ttttgcatct gcaatttcag atttctgctc
     1321 tgcatccgta tcctgctttg agagattctg ttctaactgc gtggcatgca cttttgcatc
     1381 ccatcctgaa ttctttaatt cctgctccaa cagtcttatg ttgcgcagtg cttttgcctt
     1441 tttttctttc ttcggaagat cataacccgt atggccgatc aaaactggtg cttcgtatgt
     1501 acgatattcc ttttcatcat aggcggttac ctgctcatgg attcttcccg tgtaatgaaa
     1561 actttctttt gcaaaaatac ggttgatcca ctctttattt tcctgcttgc cgtcttttcc
     1621 ggaaatgata ttgattcttt gaatccttcc aacctcgccc ggatgttcga caatcatctt
     1681 ttctaaccgt gacagatcaa tcttctgtag atattcatca ctgtcaatga ccatcacata
     1741 cggatgtgtt gcttttgaaa ccgcaaaatt ctttgctgcc gaaaaatcat cgcaccatgg
     1801 gaaatcatag atattttccg tatattctgc ggcgattttt tttgtctgat ctgtcgatcc
     1861 ggtatctact acgaccagtt caaatccggt gttctggaat gatttcaggc agcgtgccag
     1921 attgtgttct tcatttttgg tgatgatgca gactgataac atgtggttgt tctcctgtgt
     1981 gccgatcgct atattggtgg gcatattcac tcctccctgt ctgtcccaat caaaactttt
     2041 ttgccttcaa atgcaaatcc ataatgatat atctgttcct ttctgattcc tttatcaagc
     2101 aggtctgcat cgtatttttt ctcacagatc tgctttaagg cagacagaac tgtctcttga
     2161 atactttttt cctttcgtgg atttcgaact ttgaattcta aaataactgc tttgcattcc
     2221 tttgaatttt tcggttctaa cattacatca tatctgccaa acccactttc acggttggat
     2281 ttaaggtaat atctatcccg caggtcaaca agcagaccta atataaaacc atggtaaaaa
     2341 cgctcaggct ctgccccaga tgccctctct ccggtgtcga aataactaaa tgtctgtata
     2401 acaattcgat tcatgtattc attcatcgca tccacatcac caagtaacat tgcccttaca
     2461 aaatcattgt aatctggttg tacaggagca aaccagtcat gtaccatacc ctgaaacatt
     2521 aactttactt ccagattcgt caacgcaagc tggtatttcg gcatcttccc ctcctcaata
     2581 tcctgatacg tttcataaga taatactttc aaatatccac tcgccagcaa aagactccaa
     2641 actgcttttt catttccatt taattgattg tatacaatct gctcttcaat ttctgaccag
     2701 atgcattctc cgcataataa tttttcaaat ttttccttaa ttgtacggtt tccttcctga
     2761 atcaattttc ctaccagact attcgcactt gtatttgccc aaaatgtttt gtataactgt
     2821 gtatcgagat aatttaaaat tgaccatgga ttataaatat ctttgtgctc cccaaaaatg
     2881 aaaccatcgt accatctttt tacttccttt ttttctttct caagaccata ctgttccaat
     2941 gcatcaaaga cttccttctc tgtaaaacca aatacagaag catattcatt tgatgtagtc
     3001 gtaactatct ttaagttatt caaatctgaa aaaacggact ccttacttac tcttgtgatt
     3061 cccgtcataa ttccacgttc cagtgccgga ttcgttttaa atgtcgaatt aaacaggctt
     3121 cgggtgaatg cgacaagttc atcccagtaa ccatccacaa atgcttcctg catgggtgta
     3181 tcatattcgt ctaacaaaat gataactttt tttccataat atctatacag aaaatctgat
     3241 aactgatata aagaagatgt cgcatccgtc tcttttatat tttcctccaa catacgctca
     3301 taatatgctc tgtcggcatc tgtaagcttt tcactgtctt taatataaca aaactttata
     3361 tatatgtttc ttaacacctc acacatcttt tgttttgttt tctcataatc tctctcttta
     3421 atccgcgcaa atgacagact gatgacagga taagttccct gcagctcacg gtatttttct
     3481 tctttccaga ttgccagatg ttcaaacaaa tctgacctgc cggcatagtc tatggaaaag
     3541 aactgctcca ccatactcat tgtaagtgtc tttccaaaac gacgcggacg ggtgatcaaa
     3601 gtcgcactgt ccccgcaatc ccaccattct ttaataaaag gcgttttatc tatataaaaa
     3661 tagtttccct ggatgattgt ggaaaaatcc tgtataccga tcgctatatt tccagacatt
     3721 atgacctccc tgcttttcag actgatattg tgcgttcctt tttgttgtga taaattaata
     3781 atataccatt tttgtttatt ataccatatg taaccttttt accaggagaa tttcgatcta
     3841 tgaaaaaagt aagtgtcatc atcccatgtt ttaatgcaac aaaatatctt ccgaaatgct
     3901 ttatgtcact tgtacagcag acaatcggaa ttgaccagat cgaactgatc tttgtagacg
     3961 atgcatccac agatgaggat gctacctgga acatgttgca ggaatttgaa cgcgcctatc
     4021 cggaaagcat tatgatctta aaacttgagg aaaatatgcg ccagggcggt gcaagaaatg
     4081 ttgccctgca gtatgcaacg ggtgaatata ttgcatttgt tgacgctgat gactttgtcg
     4141 ctgagaattt tctgttggaa acttatgaaa aagccaaaga atcggatgct gatatcatcc
     4201 agtttgaata tttttattat acagaccgtc tgggtgccgt ggactccggt cggaacatta
     4261 tgccggaagt gattgaaatt tcttctgtca atgaccgaaa agaatttttg atctcagaga
     4321 aaattaccta tggctgctgg aataaacttt accgtcacga tcttttaaaa actgctcata
     4381 ccgcttatgc agagcatgtt atttacgaag aaccgctctt tgtatatccg cttttatatt
     4441 ttgcaaataa aatcgtaatc ttaaacgatg cctactatta ttacagacaa aatgattctg
     4501 gaaccatgcg aaatgatatg agacaggaag aaaccctaaa aatgcatgcc gatgtccaac
     4561 ttgccgtctg gaattttatg aagaatacgc cgtttttcca ggaatactat gatgaaatca
     4621 aactatattt tctccatacc tatctgtatg agacactgta ttttgcaaaa ctccgggatt
     4681 ttaaaccctc ctattctttc tacaaagaat tagaaaaaac ggtgttcaca gaggtgccgg
     4741 attattctca gtctgtgtac agtgctctga ttccgaagca gctggagctg tatcggatga
     4801 ttgaggaggg gatgacggag gagaagttcg gggggtattg tgagcggctg tgagccgctc
     4861 ccggttactc atgatgattt gttatctcaa ttgtaagtcc tcaattttct actgatgatc
     4921 aactgaatat tgatatcctc ttccagcttg aaatgcatct tcaatctgat ttgaatatga
     4981 accctctcaa gaaatttacc ttaaacttca tcaaccaatg taataatatc tttaattgac
     5041 atcagtctgt catccacttc ctttgctcta tgatatctta aaatatctgt tgcagtctgc
     5101 tgcatcgctg gaaaggcact tcttgtaagc tgattcgcat atattacaat attaattcca
     5161 tgctgttgta gttcactttc atatgtctca ttataagagg tcggcacaac gaccagagga
     5221 gtaattttat ctttttcacg aaatctgtca caaaacgcaa atatttcatc aggagttttt
     5281 tttctactgt gaatcataat gccgtctgcc cctgcgtcca catatgcaaa tgctctcaca
     5341 agtgcatcct ctaatccctt ttctaaaata aggctctcaa tccgtgcaat aatcataaaa
     5401 tcttttgtac gctgcgcacg tttccccgct ctgatttttg cagtaaagtt ttctatacta
     5461 tcctgtgtct gctctacctc tgttccaaac aaagagtttt tcttgagtcc cgtcttatcc
     5521 tcgataataa ctgctgagac ccctacacgt tctaatgttc ttacgttgta tacaaaatgc
     5581 tcaatcatac caccagtatc cccatctaat atgattggct tcgttgtaac ctccaacacg
     5641 tcatccaccg tacgaagtct ggaagacatg tctaccagtt caatatcagg ttttcctttc
     5701 gctgtcgaat cacacagact tgataaccac attgcatcaa attgatcaat ctcaccgtta
     5761 ttggccacaa ctgtcttttc cgctatcaat ccggtcagac cactatgcac ttccagtgtc
     5821 tttactattg gacataactg taataattgc cgtaaccgtt ttctacgata ttccggcata
     5881 gcagtccttt ctcgcataac agcttcaata ttccttacct gctcattata tgtatatggg
     5941 atttctatta actgacctcc ccattttttc agattttcaa tgacattatc acggatcact
     6001 tccattggat catttagcca attatctcca tgtataacat aatccggttt tattctttct
     6061 aaaatcgaac catacattac ctcgtcctga acaaccacct catccacttc cggtatctgt
     6121 tctaacattt tttttcgttc ttcaaatgat accgtcggaa agcggttata tcgaatcatt
     6181 gcagtatcac tcaatacacc tgcaatcaat tttccatatt ttttgcttcc cgaataatat
     6241 tcaggtgtcc ttcatgtatt acgtccgtgc aaaaacaagc atatactttt ttcataagcc
     6301 aaccccatga tatttcataa aattattttt attttcttct gcagtttcct ttggtctccc
     6361 cagatctgcc ctcgattgca ttgccacctt tatctcaatg aatgtaagat tccttttctt
     6421 ttttatgtca ctcaacacct ttgttaaatc ctgctgctta tccacgcaat acaccctttc
     6481 atacccaacg gtcccggcaa tatctgcata gcttaatccc acacaaccag tcggcattcc
     6541 ccctaccgat tcatgtgcgt cattattcag acaaatatgg atcaaatttt gcggtttctg
     6601 ttttgctata tatgccatac ttcccatatg cataagcact gctccatctc catccagaca
     6661 atacaccctt tttttctcta atttgtgagc cattccaagt gcgatcatag atgcatgtcc
     6721 cattccccct accgtcagga aatcctgtgc atgactccct tttattctat cactctgctc
     6781 atatacttct cttgaaatct ttcctgttgt agaaatgacg acatcacttt catccaacat
     6841 ttttattatt gccgctattg catcttctct tactaaacta ttattgtttt tataatcact
     6901 actgttatta ttctgtagaa agtctctttt caaaacaaat gcgaattgtt ttccttcttt
     6961 taacacttgt gctgctcttt caaaactacg cattatttcc tgcatagaaa gttccttttc
     7021 caacactata tattcgattt ccaacacacg cagtaagtct tccgttattt tccccatata
     7081 tttatgctga ggttcatctt tcgttcctgg ctcaccgcgc catcccacta ataataacat
     7141 tggtatgcca tatacatctt tattagcaag cgatgtaatt ggatttacta tatttcccag
     7201 cccactattc tgcatataaa cgcaggctgg tactccagtt gccaaataac tcccaatcgc
     7261 aatgccaaca gctgcccctt catttaccgg cacataatgt tcaaattcat ttttccctgt
     7321 cccattgata taatcacaaa aagactttaa tgcagaatca ggcaccccgg ctaatgtttt
     7381 tattcctatt ttttttattt gctcaacaaa atctgttact aacatgtctt atacctcgaa
     7441 tccagctggc tcaattcctc cagtgtatca acttctatta cactttccgg tgatatttcc
     7501 tctacctgaa cctttaaacg ttttaattcc tgatcaacaa tctcatccca aaataatttc
     7561 tcatgtcctg gtttcttata tgatgcttca attgcttttt ttatgattaa cgcatctgac
     7621 cttttccaat aagaaatacc tgccatgtta tatgtgtctg taccgccttt tcctactctt
     7681 gtaatattac cattttgcac atcgaatacc cagtccgaag aatagccctc tatcattttt
     7741 ccaaaataac acgaagttga atattgtctc aaaaaaatag tatcatcggg cacatacaaa
     7801 tcagcttcac aaataaaaca atctgaactt ccaagaatgt ctctcactgc atacaatgac
     7861 gaaatattgt ttttttcaaa tattctttat tttcaacaat ctctaagtta tcatattttt
     7921 ctaacaaata agaaaattgt tcttttaaat aaccaacaac aacatatatt ctttttattc
     7981 cccgccgttc taaagcgcaa ataaccgttt ctatcagagg tgttcccata acaggaacaa
     8041 gtggcttagg aatctgctct gtcagcgggc gcattcttgt acctaatcct gcagccatta
     8101 aaatagctat ctcatctttt tctttcaaca tattttaaat atccgttcct catttctggt
     8161 aatacactgg caaagaaact cccatctgct ttaatccttc ttcaaatatt tcaaagaagt
     8221 cttcaatatc agtttcgtca atagcaccta acgcacataa gcgaaatgtc tccgtattat
     8281 taattttacc cggataaatg gtaaaacctc tctcatagca gaaatcatgg atggcagaaa
     8341 aactccagtt tggatcatca ggatatttca ctgcagccac cagtcccgcc tgccattcct
     8401 tctttatcac attctgaaag cccagtcgtt caaggccact gtacaatgca tcatatactc
     8461 tggtatggcg cttccacttt tcctgctctc cttccgcaaa atactctgct attgcctgac
     8521 gcattgcata aactgtctgt actggcggcg taaagtgcat ttctccatgt ttttcgaaat
     8581 agtcatattg taaatacaaa ttgcaataat aggaacgttt gggataatct tttgacctct
     8641 ctattatgct tttattacca atcacaaatg atacacctgt catcgccatt aatccttttt
     8701 gcgcagatgc catacagaag tcaatattat ccttcttaat atcaatcggc ctcatcgcat
     8761 atgtcgatgt agtatctacc acaaaaaccg ctccataccg atgtacaagt gctccgattt
     8821 cccgcaccgg atttaagata cctgttcctg tttcattatg tgttgtatat acaagtgcta
     8881 tatcgttatt ttcttttagt acctgttcta tcagctctaa tgatggtctt tcatctattg
     8941 ggaactccag attaatgaac ggcattccat aatattcaca tatctctacc gctctggaac
     9001 tatatgctcc attattaatg atcagaattt tcttctcttc cggcaataat gaatttaaac
     9061 agacatccat agaaatcgta cccgaaccac aaaacaatac agatgtatca tcctgctcat
     9121 ctccatgcac aattttaact agatcttttc gtatctgctt cataatttca acaaattcct
     9181 gttccctcgg gcagatatcc ggcactacct gtgcctgttt tactgtatcg gttgtcgtag
     9241 ccggtcccgg atttaacaat atatttcgtt tcatagttct ctcttgtatg ataattagga
     9301 agttaattat cacatatttc ctttctttta atat
//
