## Wed Jun 26 12:49:11 2024
## emapper-2.1.12
## /d223NFS/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /d223NFS/m128030014/NGP/gene_list/prokka_results/GCA_003467035.1/GCA_003467035.1.faa --temp_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_003467035.1/2.eggNOGmapper --output_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_003467035.1/2.eggNOGmapper --output eggNOG_out --override --cpu 20 -m diamond --sensmode fast
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
KFPFDFKC_00001	622312.ROSEINA2194_03203	3.42e-233	640.0	COG1680@1|root,COG1680@2|Bacteria,1UUHI@1239|Firmicutes,24AX5@186801|Clostridia	186801|Clostridia	V	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
KFPFDFKC_00002	622312.ROSEINA2194_03202	2.24e-260	711.0	COG4733@1|root,COG4733@2|Bacteria,1UI04@1239|Firmicutes,25E8W@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
KFPFDFKC_00004	138119.DSY1048	2.47e-05	45.8	COG0640@1|root,COG0640@2|Bacteria,1V6Z2@1239|Firmicutes,24JUM@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, ArsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
KFPFDFKC_00005	397288.C806_04878	8.12e-10	56.2	COG3668@1|root,COG3668@2|Bacteria,1VD9X@1239|Firmicutes,24I2T@186801|Clostridia,27PF8@186928|unclassified Lachnospiraceae	186801|Clostridia	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K19092	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
KFPFDFKC_00006	397288.C806_04879	8.06e-55	172.0	COG3077@1|root,COG3077@2|Bacteria,1VGJW@1239|Firmicutes,24JNU@186801|Clostridia,27U7S@186928|unclassified Lachnospiraceae	186801|Clostridia	L	RelB antitoxin	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
KFPFDFKC_00007	1235799.C818_02304	7.75e-102	308.0	2EXY8@1|root,33R7C@2|Bacteria,1VSYY@1239|Firmicutes,24ZGP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00008	1235798.C817_03255	5.21e-211	586.0	COG2378@1|root,COG2378@2|Bacteria,1TSA2@1239|Firmicutes,247S2@186801|Clostridia,27V61@189330|Dorea	186801|Clostridia	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
KFPFDFKC_00009	742740.HMPREF9474_02431	1.64e-149	431.0	COG5279@1|root,COG5279@2|Bacteria,1UT8R@1239|Firmicutes,24CQF@186801|Clostridia,21YP1@1506553|Lachnoclostridium	186801|Clostridia	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
KFPFDFKC_00010	471875.RUMLAC_02133	6.3e-105	305.0	COG0778@1|root,COG0778@2|Bacteria,1V4K6@1239|Firmicutes,24B09@186801|Clostridia,3WJCA@541000|Ruminococcaceae	186801|Clostridia	C	Nitroreductase family	nfrA2	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
KFPFDFKC_00011	622312.ROSEINA2194_03189	1.34e-159	459.0	COG1403@1|root,COG1403@2|Bacteria,1U6AE@1239|Firmicutes,24D7H@186801|Clostridia	186801|Clostridia	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_4
KFPFDFKC_00012	1280694.AUJQ01000005_gene1306	2.65e-76	229.0	COG1051@1|root,COG1051@2|Bacteria,1UIGB@1239|Firmicutes,24NCA@186801|Clostridia,3NI5W@46205|Pseudobutyrivibrio	186801|Clostridia	F	NUDIX domain	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
KFPFDFKC_00013	1408436.JHXY01000019_gene1414	0.0	1628.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1TQ62@1239|Firmicutes,249TK@186801|Clostridia,25W69@186806|Eubacteriaceae	186801|Clostridia	L	Domain of unknown function (DUF3427)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3427,Helicase_C,PLDc_2,ResIII
KFPFDFKC_00014	585394.RHOM_09600	2.34e-253	697.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia	186801|Clostridia	C	Malic enzyme, NAD binding domain	maeB	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
KFPFDFKC_00015	585394.RHOM_09605	8.66e-169	477.0	COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,247U3@186801|Clostridia	186801|Clostridia	S	radical SAM protein, TIGR01212 family	ytqA	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
KFPFDFKC_00016	585394.RHOM_09610	3.79e-100	292.0	COG3432@1|root,COG3432@2|Bacteria,1V75P@1239|Firmicutes,24JAZ@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4364
KFPFDFKC_00017	585394.RHOM_09615	5.25e-117	339.0	COG1853@1|root,COG1853@2|Bacteria,1V1EA@1239|Firmicutes,24FWS@186801|Clostridia	186801|Clostridia	V	Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
KFPFDFKC_00018	585394.RHOM_09630	0.0	917.0	COG1164@1|root,COG1164@2|Bacteria,1TPV4@1239|Firmicutes,2495D@186801|Clostridia	186801|Clostridia	E	oligoendopeptidase, M3 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
KFPFDFKC_00019	585394.RHOM_09640	1.87e-116	352.0	28JJA@1|root,2Z9CD@2|Bacteria,1TPY4@1239|Firmicutes,24DSP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00020	585394.RHOM_09645	0.0	924.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,2490X@186801|Clostridia	186801|Clostridia	E	'glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
KFPFDFKC_00021	585394.RHOM_09650	0.0	2848.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,248IB@186801|Clostridia	186801|Clostridia	E	'glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
KFPFDFKC_00022	411462.DORLON_00146	9.01e-29	109.0	COG2364@1|root,COG2364@2|Bacteria,1V19X@1239|Firmicutes,24DJ8@186801|Clostridia,27VXU@189330|Dorea	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00023	33035.JPJF01000073_gene4424	3.1e-19	85.9	COG2364@1|root,COG2364@2|Bacteria,1UXHA@1239|Firmicutes,24AJQ@186801|Clostridia,3Y0DC@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00025	742723.HMPREF9477_01251	5.02e-52	168.0	COG0454@1|root,COG0456@2|Bacteria,1VAFS@1239|Firmicutes,24MUI@186801|Clostridia,27NWY@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03826	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10,Acetyltransf_7
KFPFDFKC_00026	622312.ROSEINA2194_00096	1.91e-95	288.0	COG1266@1|root,COG1266@2|Bacteria,1V7EK@1239|Firmicutes,24KV5@186801|Clostridia	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
KFPFDFKC_00027	622312.ROSEINA2194_00090	0.0	1266.0	COG0188@1|root,COG0188@2|Bacteria,1TPNX@1239|Firmicutes,24ADK@186801|Clostridia	186801|Clostridia	L	COG0188 Type IIA topoisomerase (DNA gyrase topo II, topoisomerase IV), A subunit	gyrA_1	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
KFPFDFKC_00028	585394.RHOM_09675	0.0	1204.0	COG0187@1|root,COG0187@2|Bacteria,1TRSZ@1239|Firmicutes,247ZY@186801|Clostridia	186801|Clostridia	L	COG0187 Type IIA topoisomerase (DNA gyrase topo II, topoisomerase IV), B subunit	parE	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
KFPFDFKC_00029	585394.RHOM_09685	8.88e-220	611.0	COG3835@1|root,COG3835@2|Bacteria,1TQWD@1239|Firmicutes,24ZMW@186801|Clostridia	186801|Clostridia	KT	Psort location Cytoplasmic, score	-	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30
KFPFDFKC_00030	585394.RHOM_09690	1.56e-255	702.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	ugpC_1	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
KFPFDFKC_00031	1235793.C809_04227	6.49e-106	313.0	COG0300@1|root,COG0300@2|Bacteria,1TRP8@1239|Firmicutes,24DNY@186801|Clostridia,27N1X@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
KFPFDFKC_00032	585394.RHOM_12890	1.64e-151	436.0	COG1533@1|root,COG1533@2|Bacteria,1TPA3@1239|Firmicutes,249NM@186801|Clostridia	186801|Clostridia	L	Spore photoproduct lyase	-	-	4.1.99.14	ko:K03716	-	-	-	-	ko00000,ko01000	-	-	-	-
KFPFDFKC_00033	1235802.C823_04351	3.68e-60	201.0	COG0775@1|root,COG0775@2|Bacteria,1VCJY@1239|Firmicutes,24CRR@186801|Clostridia	186801|Clostridia	F	PFAM purine or other phosphorylase family 1	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
KFPFDFKC_00034	1235802.C823_02304	5.72e-83	247.0	COG0756@1|root,COG0756@2|Bacteria,1V5PP@1239|Firmicutes,24I3J@186801|Clostridia,25W99@186806|Eubacteriaceae	186801|Clostridia	F	dUTPase	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
KFPFDFKC_00035	585394.RHOM_09700	1.48e-209	583.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia	186801|Clostridia	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
KFPFDFKC_00036	585394.RHOM_09705	4.06e-124	357.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
KFPFDFKC_00037	585394.RHOM_09710	7.84e-301	822.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
KFPFDFKC_00038	585394.RHOM_09715	5.44e-170	506.0	COG1277@1|root,COG1277@2|Bacteria,1TRJ8@1239|Firmicutes,24EMN@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
KFPFDFKC_00039	585394.RHOM_09720	9.44e-187	522.0	COG1131@1|root,COG1131@2|Bacteria,1TPQW@1239|Firmicutes,248F7@186801|Clostridia	186801|Clostridia	V	Abc transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
KFPFDFKC_00040	585394.RHOM_09725	5.37e-57	179.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,24MTU@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, GntR family	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
KFPFDFKC_00041	622312.ROSEINA2194_00078	1.85e-209	583.0	COG1363@1|root,COG1363@2|Bacteria,1TQ86@1239|Firmicutes,25CDF@186801|Clostridia	186801|Clostridia	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
KFPFDFKC_00042	622312.ROSEINA2194_00077	1.54e-145	417.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,248TD@186801|Clostridia	186801|Clostridia	L	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
KFPFDFKC_00043	622312.ROSEINA2194_00076	1.71e-55	175.0	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia	186801|Clostridia	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
KFPFDFKC_00044	585394.RHOM_09750	5.68e-49	157.0	COG2257@1|root,COG2257@2|Bacteria,1VF4R@1239|Firmicutes,24QSW@186801|Clostridia	186801|Clostridia	S	cytoplasmic domain of flagellar protein FhlB	flhB1	-	-	ko:K04061	-	-	-	-	ko00000,ko02044	-	-	-	Bac_export_2
KFPFDFKC_00045	585394.RHOM_09755	8.43e-199	580.0	28J8T@1|root,2Z93Y@2|Bacteria,1UZBP@1239|Firmicutes,24F5R@186801|Clostridia	186801|Clostridia	S	Flagellar hook-length control protein FliK	-	-	-	-	-	-	-	-	-	-	-	-	Flg_hook
KFPFDFKC_00046	585394.RHOM_09760	4.84e-135	387.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
KFPFDFKC_00047	1235790.C805_02231	1.81e-74	229.0	COG0681@1|root,COG0681@2|Bacteria,1UZ8V@1239|Firmicutes,25CN7@186801|Clostridia,25WUU@186806|Eubacteriaceae	186801|Clostridia	U	Signal peptidase, peptidase S26	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
KFPFDFKC_00048	622312.ROSEINA2194_00072	3.91e-170	479.0	COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,2490H@186801|Clostridia	186801|Clostridia	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
KFPFDFKC_00049	585394.RHOM_09770	6.26e-110	319.0	COG0681@1|root,COG0681@2|Bacteria,1V2SF@1239|Firmicutes,24AWM@186801|Clostridia	186801|Clostridia	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
KFPFDFKC_00050	585394.RHOM_05525	3.26e-237	655.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia	186801|Clostridia	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
KFPFDFKC_00051	1034345.CAEM01000003_gene1256	7.26e-20	91.7	COG2199@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,2I49F@201174|Actinobacteria,4CUE6@84998|Coriobacteriia	84998|Coriobacteriia	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GGDEF,HD,Response_reg
KFPFDFKC_00052	397287.C807_03866	1.37e-71	227.0	28S3E@1|root,2ZEF6@2|Bacteria,1V25C@1239|Firmicutes,24GTH@186801|Clostridia,27KYG@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00053	471875.RUMLAC_02383	1.1e-236	660.0	COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1TNZH@1239|Firmicutes,24BQZ@186801|Clostridia,3WHBW@541000|Ruminococcaceae	186801|Clostridia	S	Putative threonine/serine exporter	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
KFPFDFKC_00054	585394.RHOM_01185	3.61e-243	676.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
KFPFDFKC_00055	411461.DORFOR_01502	9.2e-115	336.0	28JZH@1|root,2Z9PI@2|Bacteria,1V0QF@1239|Firmicutes,248FG@186801|Clostridia,27WS8@189330|Dorea	186801|Clostridia	S	Domain of unknown function (DUF4866)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4866
KFPFDFKC_00056	585394.RHOM_01170	7.12e-124	357.0	COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes,24DUE@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
KFPFDFKC_00057	742765.HMPREF9457_00204	5.61e-143	410.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia,27VZT@189330|Dorea	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
KFPFDFKC_00058	622312.ROSEINA2194_03509	4.97e-207	575.0	COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,2486N@186801|Clostridia	186801|Clostridia	S	Belongs to the binding-protein-dependent transport system permease family	tsgC13	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
KFPFDFKC_00059	622312.ROSEINA2194_03510	5.87e-215	599.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,2494C@186801|Clostridia	186801|Clostridia	S	Belongs to the binding-protein-dependent transport system permease family	tsgB13	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
KFPFDFKC_00060	622312.ROSEINA2194_03511	0.0	884.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia	186801|Clostridia	S	Abc transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
KFPFDFKC_00061	622312.ROSEINA2194_03512	1.06e-236	659.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248IH@186801|Clostridia	186801|Clostridia	S	ABC-type transport system, periplasmic component surface lipoprotein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
KFPFDFKC_00062	585394.RHOM_05520	5.41e-115	346.0	COG0628@1|root,COG0628@2|Bacteria,1TS4S@1239|Firmicutes,248E5@186801|Clostridia	186801|Clostridia	D	Sporulation integral membrane protein YtvI	ytvI	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
KFPFDFKC_00063	585394.RHOM_05505	5.63e-208	580.0	COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,248JF@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
KFPFDFKC_00064	622312.ROSEINA2194_01040	9.89e-281	769.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,248I3@186801|Clostridia	186801|Clostridia	O	peptidase U32	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
KFPFDFKC_00065	622312.ROSEINA2194_01039	1.34e-123	355.0	COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,24B70@186801|Clostridia	186801|Clostridia	S	O-methyltransferase	yrrM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
KFPFDFKC_00066	585394.RHOM_05490	4.65e-55	178.0	COG1559@1|root,COG1559@2|Bacteria,1VGA6@1239|Firmicutes,24RBR@186801|Clostridia	186801|Clostridia	S	YceG-like family	-	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
KFPFDFKC_00067	622312.ROSEINA2194_01037	1e-47	155.0	COG3679@1|root,COG3679@2|Bacteria,1VH19@1239|Firmicutes,24RNC@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0342 family	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
KFPFDFKC_00068	585394.RHOM_05485	0.0	1020.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
KFPFDFKC_00069	622312.ROSEINA2194_01035	2.38e-36	124.0	2E3Y4@1|root,32YV4@2|Bacteria,1VFRH@1239|Firmicutes,24QXW@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
KFPFDFKC_00070	622312.ROSEINA2194_01034	1.59e-86	256.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia	186801|Clostridia	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
KFPFDFKC_00071	622312.ROSEINA2194_01033	1.4e-53	168.0	COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,24QVQ@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0297 family	yrzL	-	-	-	-	-	-	-	-	-	-	-	DUF965
KFPFDFKC_00072	585394.RHOM_05465	9.2e-253	700.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia	186801|Clostridia	J	MiaB-like tRNA modifying enzyme	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
KFPFDFKC_00073	585394.RHOM_05460	4.54e-45	145.0	COG1925@1|root,COG1925@2|Bacteria,1VAQP@1239|Firmicutes,24N19@186801|Clostridia	186801|Clostridia	G	phosphocarrier protein HPr	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
KFPFDFKC_00074	585394.RHOM_05455	6.5e-269	738.0	COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,247Y5@186801|Clostridia	186801|Clostridia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
KFPFDFKC_00075	585394.RHOM_05450	1.48e-220	615.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
KFPFDFKC_00076	585394.RHOM_05445	1.69e-107	318.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
KFPFDFKC_00077	585394.RHOM_05440	5.11e-219	606.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia	186801|Clostridia	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
KFPFDFKC_00079	622312.ROSEINA2194_01127	1.66e-153	434.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia	186801|Clostridia	E	abc transporter atp-binding protein	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
KFPFDFKC_00080	585394.RHOM_05430	1.2e-266	742.0	COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TPM3@1239|Firmicutes,248UY@186801|Clostridia	186801|Clostridia	P	Abc transporter	ArtM	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
KFPFDFKC_00081	585394.RHOM_04995	1.52e-118	346.0	COG0775@1|root,COG0775@2|Bacteria,1TSB7@1239|Firmicutes	1239|Firmicutes	F	COG0775 Nucleoside phosphorylase	-	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
KFPFDFKC_00082	622312.ROSEINA2194_01130	9.3e-102	295.0	COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,24G3R@186801|Clostridia	186801|Clostridia	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
KFPFDFKC_00083	1173026.Glo7428_1322	1.79e-52	180.0	COG0657@1|root,COG0657@2|Bacteria,1G229@1117|Cyanobacteria	1117|Cyanobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
KFPFDFKC_00084	457412.RSAG_01565	9.84e-131	372.0	COG0560@1|root,COG0560@2|Bacteria,1TQJY@1239|Firmicutes,2493S@186801|Clostridia,3WH3X@541000|Ruminococcaceae	186801|Clostridia	E	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein	thrH	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD,Hydrolase
KFPFDFKC_00085	140626.JHWB01000019_gene917	1.03e-24	104.0	COG2214@1|root,COG2214@2|Bacteria,1V4YZ@1239|Firmicutes,24U0J@186801|Clostridia	186801|Clostridia	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00086	1280694.AUJQ01000005_gene1348	1.93e-66	229.0	COG3437@1|root,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,3NGP7@46205|Pseudobutyrivibrio	186801|Clostridia	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,HisKA_7TM
KFPFDFKC_00087	585394.RHOM_05295	2.66e-271	744.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,24969@186801|Clostridia	186801|Clostridia	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
KFPFDFKC_00088	411474.COPEUT_00135	1.26e-85	268.0	COG1670@1|root,COG3393@1|root,COG1670@2|Bacteria,COG3393@2|Bacteria,1V1G4@1239|Firmicutes,24G4Y@186801|Clostridia	186801|Clostridia	J	Acetyltransferase, gnat family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
KFPFDFKC_00090	585394.RHOM_09775	7.46e-72	216.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
KFPFDFKC_00091	622312.ROSEINA2194_00064	1.84e-144	410.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
KFPFDFKC_00092	622312.ROSEINA2194_00063	9.99e-98	286.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia	186801|Clostridia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
KFPFDFKC_00094	585394.RHOM_09790	9.6e-38	127.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
KFPFDFKC_00095	622312.ROSEINA2194_00061	1.71e-49	157.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
KFPFDFKC_00096	622312.ROSEINA2194_00060	3.66e-271	748.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
KFPFDFKC_00097	585394.RHOM_09805	1.83e-62	193.0	COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,24QNM@186801|Clostridia	186801|Clostridia	S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein	-	-	-	ko:K09787	-	-	-	-	ko00000	-	-	-	UPF0122
KFPFDFKC_00099	585394.RHOM_09820	6.18e-265	728.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia	186801|Clostridia	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
KFPFDFKC_00100	622312.ROSEINA2194_00054	3.1e-199	555.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
KFPFDFKC_00101	585394.RHOM_09830	0.0	1575.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
KFPFDFKC_00102	622312.ROSEINA2194_00051	1.2e-129	372.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
KFPFDFKC_00103	585394.RHOM_09845	1.51e-41	137.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
KFPFDFKC_00104	622312.ROSEINA2194_00049	1.1e-220	612.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
KFPFDFKC_00105	585394.RHOM_09855	7.1e-80	246.0	COG5578@1|root,COG5578@2|Bacteria,1V91Z@1239|Firmicutes,24KZS@186801|Clostridia	186801|Clostridia	S	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
KFPFDFKC_00106	585394.RHOM_09870	5.07e-39	129.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,24QM0@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
KFPFDFKC_00107	622312.ROSEINA2194_00046	7.2e-95	279.0	COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia	186801|Clostridia	S	acr, cog1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
KFPFDFKC_00108	585394.RHOM_09880	4.94e-254	700.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia	186801|Clostridia	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
KFPFDFKC_00109	622312.ROSEINA2194_00044	2.52e-134	400.0	COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,247UP@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0348 family	-	-	-	-	-	-	-	-	-	-	-	-	HIGH_NTase1
KFPFDFKC_00110	585394.RHOM_09910	2.46e-270	741.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia	186801|Clostridia	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas
KFPFDFKC_00111	622312.ROSEINA2194_00040	5.17e-156	439.0	COG3363@1|root,COG3363@2|Bacteria,1TRA7@1239|Firmicutes,249ZW@186801|Clostridia	186801|Clostridia	F	IMP cyclohydrolase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	IMP_cyclohyd
KFPFDFKC_00112	585394.RHOM_09920	1.3e-136	404.0	COG4641@1|root,COG4641@2|Bacteria,1UYE0@1239|Firmicutes,24D1Q@186801|Clostridia	186801|Clostridia	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
KFPFDFKC_00113	585394.RHOM_09925	2.16e-300	822.0	COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,247K4@186801|Clostridia	186801|Clostridia	S	UPF0210 protein	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
KFPFDFKC_00114	585394.RHOM_09930	1.29e-50	161.0	COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,24QNV@186801|Clostridia	186801|Clostridia	T	Belongs to the UPF0237 family	-	-	-	ko:K07166	-	-	-	-	ko00000	-	-	-	ACT_6
KFPFDFKC_00115	585394.RHOM_09940	8.48e-157	443.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,249U2@186801|Clostridia	186801|Clostridia	J	Metallo-beta-lactamase domain protein	yycJ	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
KFPFDFKC_00116	585394.RHOM_09945	0.0	1016.0	COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,249Y7@186801|Clostridia	186801|Clostridia	D	cell division protein FtsA	ftsA	-	-	-	-	-	-	-	-	-	-	-	FtsA,MreB_Mbl
KFPFDFKC_00117	622312.ROSEINA2194_00035	3.2e-92	275.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,24GFQ@186801|Clostridia	186801|Clostridia	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
KFPFDFKC_00118	585394.RHOM_09955	0.0	1435.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
KFPFDFKC_00119	585394.RHOM_09960	0.0	1069.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia	186801|Clostridia	E	creatinase	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
KFPFDFKC_00120	622312.ROSEINA2194_00032	6.35e-100	290.0	COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,24NBX@186801|Clostridia	186801|Clostridia	S	acyl-CoA thioester hydrolase, YbgC YbaW family	FcbC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
KFPFDFKC_00121	622312.ROSEINA2194_00030	0.0	1007.0	COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,24BHM@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	GtrA,YfhO
KFPFDFKC_00122	585394.RHOM_05035	3.88e-285	800.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,2480C@186801|Clostridia	186801|Clostridia	M	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
KFPFDFKC_00125	585394.RHOM_11180	3.33e-78	260.0	2E03H@1|root,33IG6@2|Bacteria,1VKD9@1239|Firmicutes,24TED@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00126	585394.RHOM_11185	1.56e-308	842.0	COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,247JE@186801|Clostridia	186801|Clostridia	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
KFPFDFKC_00127	622312.ROSEINA2194_02991	4.2e-91	273.0	COG1595@1|root,COG1595@2|Bacteria,1TP55@1239|Firmicutes,249VX@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family	sigH	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	GerE,Sigma70_r2,Sigma70_r4_2
KFPFDFKC_00128	585394.RHOM_11195	2.3e-161	454.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
KFPFDFKC_00129	585394.RHOM_11200	3.62e-85	252.0	COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,24MR1@186801|Clostridia	186801|Clostridia	J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)	mrnC	-	-	ko:K11145	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Ribonuclease_3
KFPFDFKC_00130	585394.RHOM_11205	3.68e-313	856.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
KFPFDFKC_00131	622312.ROSEINA2194_02987	5.51e-143	406.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia	186801|Clostridia	E	serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
KFPFDFKC_00132	1280680.AUJU01000002_gene676	1.2e-39	155.0	COG2199@1|root,COG3706@2|Bacteria,1TSW8@1239|Firmicutes,249J7@186801|Clostridia,4C1VP@830|Butyrivibrio	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
KFPFDFKC_00133	1235799.C818_01516	1.21e-175	543.0	COG3210@1|root,COG3210@2|Bacteria,1UJX3@1239|Firmicutes,25FCY@186801|Clostridia,27IUC@186928|unclassified Lachnospiraceae	186801|Clostridia	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	fn3
KFPFDFKC_00134	622312.ROSEINA2194_02986	6.42e-106	308.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia	186801|Clostridia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
KFPFDFKC_00135	556261.HMPREF0240_01005	1.6e-121	365.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,36DFY@31979|Clostridiaceae	186801|Clostridia	L	domain protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,Lactamase_B
KFPFDFKC_00138	585394.RHOM_11225	0.0	1297.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,248JB@186801|Clostridia	186801|Clostridia	E	MeTHIonine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
KFPFDFKC_00139	622312.ROSEINA2194_01929	1.09e-231	640.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
KFPFDFKC_00140	585394.RHOM_11245	5.28e-75	236.0	COG1345@1|root,COG1345@2|Bacteria,1V9AS@1239|Firmicutes,24MHW@186801|Clostridia	186801|Clostridia	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00141	622312.ROSEINA2194_01931	1.06e-156	440.0	COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,247N9@186801|Clostridia	186801|Clostridia	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
KFPFDFKC_00142	622312.ROSEINA2194_01932	4.41e-169	473.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,24900@186801|Clostridia	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
KFPFDFKC_00143	622312.ROSEINA2194_01933	1.52e-116	336.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
KFPFDFKC_00144	622312.ROSEINA2194_01934	3.23e-43	166.0	2DM0G@1|root,31677@2|Bacteria,1UIGR@1239|Firmicutes,25EN6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00145	585394.RHOM_11275	3.8e-199	553.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1TRJU@1239|Firmicutes,24AQW@186801|Clostridia	186801|Clostridia	T	response regulator receiver	cheV	-	2.7.13.3	ko:K03407,ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,Response_reg
KFPFDFKC_00147	1235790.C805_02256	1.08e-26	110.0	2C0VN@1|root,32VTP@2|Bacteria,1VAWW@1239|Firmicutes,24N54@186801|Clostridia,25XSI@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4352
KFPFDFKC_00148	622312.ROSEINA2194_01937	1.78e-252	706.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
KFPFDFKC_00149	1235802.C823_02421	2.69e-136	389.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia,25UU1@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	srrA_6	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
KFPFDFKC_00150	622312.ROSEINA2194_01939	6.29e-53	176.0	2DSWH@1|root,32UTX@2|Bacteria,1VBEP@1239|Firmicutes,24PR0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00151	1469948.JPNB01000001_gene964	5.08e-250	693.0	COG1501@1|root,COG1501@2|Bacteria,1UJ1V@1239|Firmicutes,24AVU@186801|Clostridia,36HI8@31979|Clostridiaceae	186801|Clostridia	G	Alpha galactosidase A	-	-	-	-	-	-	-	-	-	-	-	-	Melibiase_2
KFPFDFKC_00152	1469948.JPNB01000002_gene3625	0.0	1004.0	COG3533@1|root,COG3533@2|Bacteria,1TNYA@1239|Firmicutes,24841@186801|Clostridia,36FIY@31979|Clostridiaceae	186801|Clostridia	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
KFPFDFKC_00153	585394.RHOM_04085	0.0	1019.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,249UZ@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23,3.2.1.31	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01105,R01478,R01678,R03355,R04783,R04979,R06114,R07818,R08127,R08260,R10830	RC00049,RC00055,RC00171,RC00452,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
KFPFDFKC_00154	1469948.JPNB01000002_gene3623	9.6e-155	452.0	COG3507@1|root,COG5492@1|root,COG3507@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,Glyco_hydro_43,Laminin_G_3
KFPFDFKC_00155	1469948.JPNB01000002_gene3621	0.0	960.0	COG1874@1|root,COG1874@2|Bacteria,1TSHK@1239|Firmicutes,249IJ@186801|Clostridia,36E91@31979|Clostridiaceae	186801|Clostridia	G	Glycosyl hydrolases family 35	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_35
KFPFDFKC_00156	1280676.AUJO01000001_gene2223	2.36e-314	866.0	COG1653@1|root,COG1653@2|Bacteria,1TR5P@1239|Firmicutes,24F0C@186801|Clostridia,4C20R@830|Butyrivibrio	186801|Clostridia	G	Domain of unknown function (DUF3502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3502,SBP_bac_1
KFPFDFKC_00157	1280685.AUKC01000052_gene1365	8.72e-178	499.0	COG0395@1|root,COG0395@2|Bacteria,1TS9S@1239|Firmicutes,24BF3@186801|Clostridia,4BWPH@830|Butyrivibrio	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K17320	ko02010,map02010	M00207,M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
KFPFDFKC_00158	515622.bpr_I0935	8.78e-179	506.0	COG4209@1|root,COG4209@2|Bacteria,1TT63@1239|Firmicutes,25C4W@186801|Clostridia,4BW6J@830|Butyrivibrio	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
KFPFDFKC_00159	556261.HMPREF0240_00813	9.63e-122	361.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,248BZ@186801|Clostridia,36E93@31979|Clostridiaceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
KFPFDFKC_00160	1469948.JPNB01000002_gene3622	1.06e-201	573.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,36FU2@31979|Clostridiaceae	186801|Clostridia	V	Mate efflux family protein	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
KFPFDFKC_00161	1469948.JPNB01000002_gene3616	0.0	1001.0	COG3250@1|root,COG3250@2|Bacteria,1TPK7@1239|Firmicutes,247VE@186801|Clostridia,36FQM@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
KFPFDFKC_00162	658086.HMPREF0994_04316	1.03e-83	261.0	COG2207@1|root,COG2207@2|Bacteria,1UGXT@1239|Firmicutes,24EUQ@186801|Clostridia,27NK5@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
KFPFDFKC_00163	1226325.HMPREF1548_02854	1.91e-213	597.0	COG4225@1|root,COG4225@2|Bacteria,1TR4A@1239|Firmicutes,248Z1@186801|Clostridia,36F9Z@31979|Clostridiaceae	186801|Clostridia	S	Glucuronyl hydrolase	-	-	3.2.1.180	ko:K18581	-	-	R10867	RC00049,RC02427	ko00000,ko01000	-	GH88	-	Glyco_hydro_88
KFPFDFKC_00164	585394.RHOM_04080	0.0	915.0	COG3387@1|root,COG3387@2|Bacteria,1UI0N@1239|Firmicutes,25DI4@186801|Clostridia	186801|Clostridia	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_N
KFPFDFKC_00165	1256908.HMPREF0373_03204	0.0	1030.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,25V6K@186806|Eubacteriaceae	186801|Clostridia	J	L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
KFPFDFKC_00166	585394.RHOM_11610	1.66e-271	746.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia	186801|Clostridia	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
KFPFDFKC_00167	537007.BLAHAN_06184	1.8e-186	520.0	COG2207@1|root,COG2207@2|Bacteria,1TXIY@1239|Firmicutes,248D1@186801|Clostridia,3Y2AU@572511|Blautia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
KFPFDFKC_00168	742741.HMPREF9475_00686	1.08e-46	161.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,21ZU8@1506553|Lachnoclostridium	186801|Clostridia	G	MFS/sugar transport protein	uidB_2	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
KFPFDFKC_00169	1235802.C823_01636	3.99e-272	749.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,25V9R@186806|Eubacteriaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
KFPFDFKC_00170	1235802.C823_01635	0.0	2089.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,25V34@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
KFPFDFKC_00171	1235798.C817_03206	4.58e-213	587.0	COG2207@1|root,COG2207@2|Bacteria,1TR2K@1239|Firmicutes,24ABH@186801|Clostridia,27W0B@189330|Dorea	186801|Clostridia	K	AraC-like ligand binding domain	araC_2	-	-	ko:K02099	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18,HTH_AraC
KFPFDFKC_00172	1235790.C805_00155	8.76e-145	414.0	COG1396@1|root,COG1396@2|Bacteria,1VF0W@1239|Firmicutes,24R43@186801|Clostridia,25XCU@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
KFPFDFKC_00173	1280689.AUJC01000001_gene2021	0.0	1058.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,36DU1@31979|Clostridiaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
KFPFDFKC_00174	665950.HMPREF1025_01152	4.5e-280	765.0	COG2946@1|root,COG2946@2|Bacteria,1UHNT@1239|Firmicutes,24ZUP@186801|Clostridia,27KKS@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Replication initiation factor	-	-	-	ko:K07467	-	-	-	-	ko00000	-	-	-	HTH_3,Rep_trans
KFPFDFKC_00175	665950.HMPREF1025_01151	1.92e-38	128.0	2DIIC@1|root,303DD@2|Bacteria,1TUYY@1239|Firmicutes,25A0Z@186801|Clostridia,27T5H@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
KFPFDFKC_00176	665950.HMPREF1025_01150	2.02e-51	161.0	2EHZK@1|root,33BR3@2|Bacteria,1VKWR@1239|Firmicutes,25NCX@186801|Clostridia,27NXM@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00178	665950.HMPREF1025_01148	3.04e-129	370.0	2DG4Z@1|root,2ZUIM@2|Bacteria,1V47V@1239|Firmicutes,24HN9@186801|Clostridia,27NDI@186928|unclassified Lachnospiraceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
KFPFDFKC_00179	500632.CLONEX_00599	1.39e-196	545.0	COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,247NW@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
KFPFDFKC_00180	500632.CLONEX_00598	7.58e-77	229.0	COG1725@1|root,COG1725@2|Bacteria,1V9ZC@1239|Firmicutes,24NTW@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
KFPFDFKC_00181	411461.DORFOR_02639	1.58e-15	74.7	COG1396@1|root,COG1396@2|Bacteria,1VF0W@1239|Firmicutes,24R43@186801|Clostridia,27W3Z@189330|Dorea	186801|Clostridia	K	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
KFPFDFKC_00182	411474.COPEUT_00550	1.21e-14	73.9	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia	186801|Clostridia	L	PFAM transposase, mutator	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
KFPFDFKC_00183	1121115.AXVN01000132_gene727	4.8e-14	68.6	2CUHA@1|root,30KV1@2|Bacteria,1V52Z@1239|Firmicutes,24I1N@186801|Clostridia,3Y1IQ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00184	585394.RHOM_11645	1.22e-280	776.0	COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,247JT@186801|Clostridia	186801|Clostridia	H	coproporphyrinogen	hemZ	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
KFPFDFKC_00185	585394.RHOM_11650	3.32e-124	356.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia	186801|Clostridia	P	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
KFPFDFKC_00186	622312.ROSEINA2194_02168	0.0	1385.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
KFPFDFKC_00187	585394.RHOM_11660	1.99e-79	250.0	COG1670@1|root,COG1670@2|Bacteria,1V4FZ@1239|Firmicutes,24PF4@186801|Clostridia	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
KFPFDFKC_00188	1410650.JHWL01000003_gene2985	2.35e-48	187.0	28I6K@1|root,2Z89I@2|Bacteria,1UQ1M@1239|Firmicutes,24A0B@186801|Clostridia,4BWIK@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00189	585394.RHOM_04030	9.98e-195	542.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia	186801|Clostridia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
KFPFDFKC_00190	622312.ROSEINA2194_02248	1.78e-163	459.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
KFPFDFKC_00191	585394.RHOM_04020	1.65e-267	738.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
KFPFDFKC_00192	585394.RHOM_04015	2.74e-246	682.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
KFPFDFKC_00193	622312.ROSEINA2194_02245	8.78e-143	418.0	COG0457@1|root,COG0457@2|Bacteria,1V4J9@1239|Firmicutes,24HT2@186801|Clostridia	186801|Clostridia	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
KFPFDFKC_00194	1415775.U729_2133	5.02e-73	223.0	COG3153@1|root,COG3153@2|Bacteria,1UK0D@1239|Firmicutes,25FG9@186801|Clostridia,36V06@31979|Clostridiaceae	186801|Clostridia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_9
KFPFDFKC_00195	585394.RHOM_05980	1.66e-62	197.0	COG1595@1|root,COG1595@2|Bacteria,1V734@1239|Firmicutes,24MQB@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	sigV	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
KFPFDFKC_00196	585394.RHOM_05985	1e-107	323.0	COG5513@1|root,COG5513@2|Bacteria,1UIU3@1239|Firmicutes,25ERV@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3298)	rsiV	-	-	-	-	-	-	-	-	-	-	-	DUF3298,DUF4163
KFPFDFKC_00197	411902.CLOBOL_02174	2.65e-155	455.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,21Z7N@1506553|Lachnoclostridium	186801|Clostridia	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
KFPFDFKC_00198	742733.HMPREF9469_01435	1.13e-55	188.0	COG2755@1|root,COG2755@2|Bacteria,1V2MD@1239|Firmicutes,24FWG@186801|Clostridia,2201W@1506553|Lachnoclostridium	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
KFPFDFKC_00199	585394.RHOM_04340	1.94e-260	718.0	28HI8@1|root,2Z7TS@2|Bacteria,1TQTK@1239|Firmicutes,249WK@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4317
KFPFDFKC_00200	585394.RHOM_04335	2.26e-87	259.0	COG1329@1|root,COG1329@2|Bacteria,1VAA0@1239|Firmicutes,24P60@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
KFPFDFKC_00201	485916.Dtox_1961	1.37e-11	78.6	COG3210@1|root,COG3656@1|root,COG5492@1|root,COG3210@2|Bacteria,COG3656@2|Bacteria,COG5492@2|Bacteria,1VUQN@1239|Firmicutes,24CDA@186801|Clostridia,267DX@186807|Peptococcaceae	186801|Clostridia	N	PFAM Bacterial Ig-like domain (group 2)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,F5_F8_type_C,FIVAR,Flg_new,RHS_repeat,SH3_3,SLH,fn3
KFPFDFKC_00202	526218.Sterm_4199	1.74e-50	174.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
KFPFDFKC_00203	585394.RHOM_04285	2.65e-246	676.0	COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia	186801|Clostridia	G	Kinase, PfkB family	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
KFPFDFKC_00204	622312.ROSEINA2194_04459	5.14e-225	622.0	COG0524@1|root,COG0524@2|Bacteria,1TQ9Q@1239|Firmicutes,25B0T@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
KFPFDFKC_00205	585394.RHOM_04000	1.62e-131	387.0	COG2355@1|root,COG2355@2|Bacteria,1UA7M@1239|Firmicutes,24AE6@186801|Clostridia	186801|Clostridia	E	PFAM Peptidase M19, renal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
KFPFDFKC_00206	500632.CLONEX_03577	3.46e-32	134.0	COG0772@1|root,COG0772@2|Bacteria,1TRIP@1239|Firmicutes,25DEX@186801|Clostridia	186801|Clostridia	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
KFPFDFKC_00207	1235798.C817_04466	1.18e-43	145.0	COG1695@1|root,COG1695@2|Bacteria,1VAKA@1239|Firmicutes,24MVF@186801|Clostridia,27VT5@189330|Dorea	186801|Clostridia	K	Transcriptional regulator, PadR family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
KFPFDFKC_00208	592026.GCWU0000282_001791	6.1e-55	179.0	COG0685@1|root,COG0685@2|Bacteria,1TQFE@1239|Firmicutes,247ZK@186801|Clostridia	186801|Clostridia	E	5,10-methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
KFPFDFKC_00209	411463.EUBVEN_02650	6.58e-46	157.0	COG0583@1|root,COG0583@2|Bacteria,1TP3E@1239|Firmicutes,248HI@186801|Clostridia,25VUS@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
KFPFDFKC_00210	1280679.ATVX01000004_gene452	6.3e-07	51.2	29155@1|root,2ZNSF@2|Bacteria,1W51U@1239|Firmicutes,257BM@186801|Clostridia,4C0H7@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00211	585394.RHOM_03995	0.0	1375.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	malP_1	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
KFPFDFKC_00212	622312.ROSEINA2194_02243	5.79e-168	474.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1TSRS@1239|Firmicutes,24BXX@186801|Clostridia	186801|Clostridia	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
KFPFDFKC_00213	585394.RHOM_03350	1.05e-214	615.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9
KFPFDFKC_00214	585394.RHOM_11515	3.34e-57	183.0	COG0671@1|root,COG0671@2|Bacteria,1VB2R@1239|Firmicutes,24MQ9@186801|Clostridia	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
KFPFDFKC_00215	585394.RHOM_11510	2.66e-66	205.0	COG0597@1|root,COG0597@2|Bacteria,1VFDG@1239|Firmicutes,24PUH@186801|Clostridia	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	-	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
KFPFDFKC_00216	1235790.C805_02487	2.01e-70	220.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1URF2@1239|Firmicutes,24BBP@186801|Clostridia,25ZEW@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
KFPFDFKC_00217	1235792.C808_04909	1.12e-53	171.0	COG1943@1|root,COG1943@2|Bacteria,1TSQ0@1239|Firmicutes,25CMS@186801|Clostridia,27U60@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
KFPFDFKC_00218	1410630.JNKP01000001_gene1787	1.63e-120	352.0	COG0726@1|root,COG0726@2|Bacteria,1U0B6@1239|Firmicutes,24895@186801|Clostridia,27M6G@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
KFPFDFKC_00219	585394.RHOM_04190	5.46e-62	195.0	COG4767@1|root,COG4767@2|Bacteria,1VAH6@1239|Firmicutes,24MQR@186801|Clostridia	186801|Clostridia	V	Glycopeptide antibiotics resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
KFPFDFKC_00220	585394.RHOM_04185	7.55e-143	405.0	COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
KFPFDFKC_00222	585394.RHOM_03840	3.86e-74	228.0	COG1595@1|root,COG1595@2|Bacteria,1V1JW@1239|Firmicutes,24FYN@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
KFPFDFKC_00223	658086.HMPREF0994_04050	9.46e-116	356.0	COG4826@1|root,COG4826@2|Bacteria,1UYKX@1239|Firmicutes,24B76@186801|Clostridia,27KFI@186928|unclassified Lachnospiraceae	186801|Clostridia	O	SERine  Proteinase INhibitors	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
KFPFDFKC_00224	622312.ROSEINA2194_02179	6.26e-32	118.0	2E5D8@1|root,33058@2|Bacteria,1VERG@1239|Firmicutes,24S0M@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1344
KFPFDFKC_00225	585394.RHOM_11845	7.01e-107	315.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,24JSE@186801|Clostridia	186801|Clostridia	G	xylanase chitin deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
KFPFDFKC_00226	397290.C810_02286	9.37e-124	370.0	COG1668@1|root,COG1668@2|Bacteria,1TQNC@1239|Firmicutes,2489Z@186801|Clostridia,27I77@186928|unclassified Lachnospiraceae	186801|Clostridia	CP	ABC-2 family transporter protein	natB	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,ABC2_membrane_3,Abi
KFPFDFKC_00227	1235790.C805_02060	1.35e-131	379.0	COG4555@1|root,COG4555@2|Bacteria,1UHYH@1239|Firmicutes,25E73@186801|Clostridia	186801|Clostridia	CP	ABC transporter	natA	-	3.6.3.7	ko:K09697	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.115	-	-	ABC_tran
KFPFDFKC_00228	585394.RHOM_11850	1.05e-19	93.2	COG1670@1|root,COG1670@2|Bacteria,1UHY0@1239|Firmicutes,25EFE@186801|Clostridia	186801|Clostridia	J	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
KFPFDFKC_00229	622312.ROSEINA2194_00544	1.84e-219	608.0	COG0463@1|root,COG0463@2|Bacteria,1TT6C@1239|Firmicutes,248F2@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	kfoC_2	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
KFPFDFKC_00230	622312.ROSEINA2194_00543	4.9e-246	679.0	COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,249BR@186801|Clostridia	186801|Clostridia	M	UDP-galactopyranose mutase	glf	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,NAD_binding_8
KFPFDFKC_00231	622312.ROSEINA2194_00542	2.04e-186	528.0	COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,25E4K@186801|Clostridia	186801|Clostridia	L	A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4,SfsA
KFPFDFKC_00232	585394.RHOM_11880	4.76e-255	702.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia	186801|Clostridia	E	PFAM aminotransferase class I and II	yugH	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
KFPFDFKC_00233	1408312.JNJS01000004_gene2375	7.78e-170	476.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,3NGQJ@46205|Pseudobutyrivibrio	186801|Clostridia	I	Enoyl-CoA hydratase/isomerase	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
KFPFDFKC_00234	1280668.ATVT01000002_gene3088	5.34e-20	88.6	COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,24ACC@186801|Clostridia,4BYMQ@830|Butyrivibrio	186801|Clostridia	S	Sodium Bile acid symporter family	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
KFPFDFKC_00235	585394.RHOM_00265	1.59e-184	515.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UZ35@1239|Firmicutes,25BI3@186801|Clostridia	186801|Clostridia	K	COG2207 AraC-type DNA-binding domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
KFPFDFKC_00236	585394.RHOM_00260	5.41e-280	769.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
KFPFDFKC_00237	585394.RHOM_11890	2.67e-144	412.0	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,247SR@186801|Clostridia	186801|Clostridia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
KFPFDFKC_00238	585394.RHOM_11895	5.67e-296	810.0	COG0366@1|root,COG0366@2|Bacteria,1TQFJ@1239|Firmicutes,249Y3@186801|Clostridia	186801|Clostridia	G	Alpha amylase, catalytic domain protein	-	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Alpha-amylase_N
KFPFDFKC_00239	397290.C810_01003	1.51e-71	218.0	COG4506@1|root,COG4506@2|Bacteria,1V8CS@1239|Firmicutes,24JQR@186801|Clostridia,27N6U@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF1934)	ywiB	-	-	-	-	-	-	-	-	-	-	-	DUF1934
KFPFDFKC_00240	622312.ROSEINA2194_03400	1.9e-69	218.0	2AUKD@1|root,31K93@2|Bacteria,1V6PK@1239|Firmicutes,24J91@186801|Clostridia	186801|Clostridia	S	stage ii sporulation protein r	spoIIR	-	-	ko:K06387	-	-	-	-	ko00000	-	-	-	Spore_II_R
KFPFDFKC_00241	585394.RHOM_11780	6.74e-214	622.0	COG0814@1|root,COG0814@2|Bacteria,1V9NE@1239|Firmicutes,25DGZ@186801|Clostridia	186801|Clostridia	E	Spore germination protein	-	-	-	-	-	-	-	-	-	-	-	-	Spore_permease
KFPFDFKC_00242	585394.RHOM_11785	3.68e-293	807.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,248Q8@186801|Clostridia	186801|Clostridia	EG	GerA spore germination protein	gerA	-	-	ko:K06310	-	-	-	-	ko00000	-	-	-	GerA
KFPFDFKC_00243	622312.ROSEINA2194_03403	7.82e-129	369.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24C0U@186801|Clostridia	186801|Clostridia	K	domain protein	GntR	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
KFPFDFKC_00244	622312.ROSEINA2194_03404	6.15e-170	479.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia	186801|Clostridia	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
KFPFDFKC_00245	585394.RHOM_11800	9.48e-90	269.0	2BYUV@1|root,307Y4@2|Bacteria,1V64G@1239|Firmicutes,24K9A@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00246	585394.RHOM_11810	2.93e-299	817.0	COG1167@1|root,COG1167@2|Bacteria,1TPMY@1239|Firmicutes,24986@186801|Clostridia	186801|Clostridia	EK	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_MocR
KFPFDFKC_00247	585394.RHOM_11815	7.72e-281	772.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia	186801|Clostridia	L	ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
KFPFDFKC_00248	1410628.JNKS01000072_gene1060	5.22e-158	457.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,27IMU@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iHN637.CLJU_RS20420	Mur_ligase_C,Mur_ligase_M
KFPFDFKC_00249	1408323.JQKK01000003_gene2632	4.23e-184	527.0	COG0603@1|root,COG0603@2|Bacteria,1V0EU@1239|Firmicutes,24BK5@186801|Clostridia,27KYX@186928|unclassified Lachnospiraceae	186801|Clostridia	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00250	585394.RHOM_11905	8.51e-205	585.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia	186801|Clostridia	O	PDZ DHR GLGF domain protein	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
KFPFDFKC_00251	585394.RHOM_11910	5e-177	510.0	2DSN8@1|root,33GRU@2|Bacteria,1VPDR@1239|Firmicutes,24PGY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00252	585394.RHOM_11920	1.03e-159	456.0	COG1216@1|root,COG1216@2|Bacteria,1TSXW@1239|Firmicutes,2499G@186801|Clostridia	186801|Clostridia	S	Glycosyltransferase, group 2 family protein	-	-	-	ko:K12992	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
KFPFDFKC_00253	585394.RHOM_11925	2.56e-187	530.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia	186801|Clostridia	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
KFPFDFKC_00254	585394.RHOM_11930	1.51e-300	824.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia	186801|Clostridia	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	-	-	2.7.8.6	ko:K00996	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Bac_transf,CoA_binding_3
KFPFDFKC_00255	622312.ROSEINA2194_02504	6.24e-155	443.0	COG1216@1|root,COG1216@2|Bacteria,1TSTE@1239|Firmicutes,249WH@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
KFPFDFKC_00256	585394.RHOM_11940	0.0	914.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
KFPFDFKC_00257	585394.RHOM_11945	7.2e-33	114.0	2E96G@1|root,333F2@2|Bacteria,1VHVR@1239|Firmicutes,24SE5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00258	585394.RHOM_11950	0.0	1135.0	COG0463@1|root,COG1216@1|root,COG0463@2|Bacteria,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
KFPFDFKC_00259	483218.BACPEC_02375	1.13e-207	583.0	COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,25B1W@186801|Clostridia,2682F@186813|unclassified Clostridiales	186801|Clostridia	M	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
KFPFDFKC_00260	585394.RHOM_11955	2.11e-157	448.0	COG2333@1|root,COG2333@2|Bacteria,1UEY5@1239|Firmicutes,24E8K@186801|Clostridia	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
KFPFDFKC_00262	585394.RHOM_11965	5.86e-61	189.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
KFPFDFKC_00263	585394.RHOM_12000	7.03e-258	714.0	COG0836@1|root,COG1917@1|root,COG0836@2|Bacteria,COG1917@2|Bacteria,1TPC9@1239|Firmicutes,24908@186801|Clostridia	186801|Clostridia	M	PFAM Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
KFPFDFKC_00264	585394.RHOM_12005	4.97e-221	610.0	COG0451@1|root,COG0451@2|Bacteria,1TQV2@1239|Firmicutes,249R2@186801|Clostridia	186801|Clostridia	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
KFPFDFKC_00265	585394.RHOM_12010	1.91e-236	651.0	COG1089@1|root,COG1089@2|Bacteria,1TQ9T@1239|Firmicutes,24863@186801|Clostridia	186801|Clostridia	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
KFPFDFKC_00266	585394.RHOM_12015	5.71e-142	409.0	COG2207@1|root,COG2207@2|Bacteria,1V1FV@1239|Firmicutes,24887@186801|Clostridia	186801|Clostridia	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
KFPFDFKC_00267	585394.RHOM_12025	5e-113	338.0	COG3594@1|root,COG3594@2|Bacteria,1VJ6T@1239|Firmicutes,24UK1@186801|Clostridia	186801|Clostridia	G	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
KFPFDFKC_00268	483218.BACPEC_02363	1.54e-293	819.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,247YA@186801|Clostridia,268P3@186813|unclassified Clostridiales	186801|Clostridia	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
KFPFDFKC_00269	585394.RHOM_12030	5.76e-120	348.0	COG1922@1|root,COG1922@2|Bacteria,1UIHR@1239|Firmicutes,25BDH@186801|Clostridia	186801|Clostridia	M	Belongs to the glycosyltransferase 26 family	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	CoA_binding_3,Glyco_tran_WecB
KFPFDFKC_00270	585394.RHOM_12035	5.87e-92	280.0	2DMX9@1|root,32U7V@2|Bacteria,1W0SU@1239|Firmicutes,24QVG@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00271	585394.RHOM_12040	2.44e-252	711.0	COG1132@1|root,COG1132@2|Bacteria,1TQAN@1239|Firmicutes,24BEK@186801|Clostridia	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
KFPFDFKC_00272	585394.RHOM_12075	1.46e-107	320.0	arCOG09486@1|root,2ZC3Y@2|Bacteria,1VABR@1239|Firmicutes,24F51@186801|Clostridia	186801|Clostridia	S	Glycosyl transferase family 11	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_11
KFPFDFKC_00273	1123307.KB904364_gene1166	4.44e-76	255.0	COG1807@1|root,COG1807@2|Bacteria,1V11Z@1239|Firmicutes,4ISNZ@91061|Bacilli	91061|Bacilli	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
KFPFDFKC_00275	632245.CLP_3145	5.77e-97	293.0	COG0382@1|root,COG0382@2|Bacteria,1TRTB@1239|Firmicutes,24AQ0@186801|Clostridia,36E6F@31979|Clostridiaceae	186801|Clostridia	H	PFAM UbiA prenyltransferase	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
KFPFDFKC_00276	585394.RHOM_11975	1.16e-129	395.0	28PI9@1|root,2ZC8C@2|Bacteria,1V6ZI@1239|Firmicutes,24M4V@186801|Clostridia	186801|Clostridia	S	Glucosyl transferase GtrII	-	-	-	-	-	-	-	-	-	-	-	-	Glucos_trans_II
KFPFDFKC_00277	1235793.C809_03429	2.91e-85	266.0	2DBCR@1|root,2Z8FA@2|Bacteria,1V8ZT@1239|Firmicutes,24KB5@186801|Clostridia,27MF2@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00278	489825.LYNGBM3L_09380	1.07e-16	87.0	2C7E6@1|root,32JF5@2|Bacteria,1G9FH@1117|Cyanobacteria,1HG1Y@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00279	585394.RHOM_12020	4.37e-59	201.0	COG3274@1|root,COG3274@2|Bacteria,1V90B@1239|Firmicutes,24IC7@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
KFPFDFKC_00280	877424.ATWC01000003_gene1798	1.05e-27	119.0	COG3274@1|root,COG3274@2|Bacteria,1VFZD@1239|Firmicutes,25D9I@186801|Clostridia	186801|Clostridia	S	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
KFPFDFKC_00281	626369.HMPREF0446_00571	1.08e-27	118.0	COG0438@1|root,COG0438@2|Bacteria,1UZFG@1239|Firmicutes,4ISTK@91061|Bacilli	91061|Bacilli	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00284	585394.RHOM_12090	4.06e-201	563.0	COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,24EHG@186801|Clostridia	186801|Clostridia	D	Protein of unknown function (DUF3048) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
KFPFDFKC_00285	397288.C806_01854	2.16e-83	285.0	COG5279@1|root,COG5279@2|Bacteria,1VEK2@1239|Firmicutes,24SMT@186801|Clostridia,27NZA@186928|unclassified Lachnospiraceae	186801|Clostridia	D	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,Transglut_core
KFPFDFKC_00286	585394.RHOM_12095	3.79e-189	529.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,248Q5@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
KFPFDFKC_00287	1410658.JHWI01000034_gene1952	8.88e-178	501.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,3VP1J@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
KFPFDFKC_00288	515620.EUBELI_00113	1.95e-64	201.0	COG2246@1|root,COG2246@2|Bacteria,1VESW@1239|Firmicutes,24QSN@186801|Clostridia,25XGV@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
KFPFDFKC_00289	585394.RHOM_03215	3.17e-37	125.0	2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,24QPW@186801|Clostridia	186801|Clostridia	S	'small, acid-soluble spore protein	sasP	-	-	ko:K06421	-	-	-	-	ko00000	-	-	-	SASP
KFPFDFKC_00290	585394.RHOM_03145	2.47e-103	301.0	COG0693@1|root,COG0693@2|Bacteria,1V3WB@1239|Firmicutes,24HGU@186801|Clostridia	186801|Clostridia	S	DJ-1 family	yajL	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
KFPFDFKC_00291	585394.RHOM_03140	4.82e-88	260.0	COG2954@1|root,COG2954@2|Bacteria,1V7MS@1239|Firmicutes,24JER@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
KFPFDFKC_00292	585394.RHOM_03135	2.43e-160	459.0	COG2263@1|root,COG2263@2|Bacteria,1TQUZ@1239|Firmicutes,248AM@186801|Clostridia	186801|Clostridia	J	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
KFPFDFKC_00294	585394.RHOM_03130	1.03e-64	206.0	COG4728@1|root,COG4728@2|Bacteria,1VENJ@1239|Firmicutes,24SFD@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653
KFPFDFKC_00296	610130.Closa_2435	4.55e-178	512.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,21XK8@1506553|Lachnoclostridium	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
KFPFDFKC_00297	397287.C807_00819	4.68e-107	313.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia,27KNA@186928|unclassified Lachnospiraceae	186801|Clostridia	P	TrkA-N domain	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
KFPFDFKC_00298	585394.RHOM_03075	1.6e-192	543.0	COG1453@1|root,COG1453@2|Bacteria,1TQ5N@1239|Firmicutes,247SD@186801|Clostridia	186801|Clostridia	C	aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17,Fer4_9
KFPFDFKC_00299	585394.RHOM_03065	3.88e-122	351.0	COG1102@1|root,COG1102@2|Bacteria,1V1PJ@1239|Firmicutes,24GMN@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
KFPFDFKC_00300	622312.ROSEINA2194_00695	3.32e-151	427.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia	186801|Clostridia	E	Abc transporter	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
KFPFDFKC_00301	622312.ROSEINA2194_00694	2.95e-162	456.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,2490B@186801|Clostridia	186801|Clostridia	E	Abc transporter	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
KFPFDFKC_00302	585394.RHOM_03050	7.41e-207	578.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,248WH@186801|Clostridia	186801|Clostridia	E	Belongs to the binding-protein-dependent transport system permease family	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
KFPFDFKC_00303	585394.RHOM_03045	4.99e-179	502.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,2480A@186801|Clostridia	186801|Clostridia	E	Belongs to the binding-protein-dependent transport system permease family	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
KFPFDFKC_00304	622312.ROSEINA2194_00691	6.04e-217	607.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia	186801|Clostridia	E	PFAM Extracellular ligand-binding receptor	braC	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
KFPFDFKC_00307	592026.GCWU0000282_003027	5.62e-206	587.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	appF	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
KFPFDFKC_00308	1449050.JNLE01000005_gene4146	7.26e-206	573.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,36DZS@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
KFPFDFKC_00309	1449050.JNLE01000005_gene4147	6.91e-142	431.0	COG1173@1|root,COG5184@1|root,COG1173@2|Bacteria,COG5184@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,36E1E@31979|Clostridiaceae	186801|Clostridia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N,RCC1_2
KFPFDFKC_00310	592026.GCWU0000282_003030	1.44e-137	400.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	appB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
KFPFDFKC_00311	1449050.JNLE01000005_gene4149	7.3e-165	493.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,36WU1@31979|Clostridiaceae	186801|Clostridia	E	Extracellular solute-binding protein, family 5	-	-	-	ko:K02035,ko:K15584	ko02010,ko02024,map02010,map02024	M00239,M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
KFPFDFKC_00312	585394.RHOM_02970	2.3e-41	138.0	2C1ED@1|root,33FE6@2|Bacteria,1VKWJ@1239|Firmicutes,24VDX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00313	585394.RHOM_08575	0.0	910.0	COG0840@1|root,COG0840@2|Bacteria,1UYFA@1239|Firmicutes,24F3M@186801|Clostridia	186801|Clostridia	NT	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal,PilZ
KFPFDFKC_00314	622312.ROSEINA2194_01478	4.41e-201	582.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1,sCache_2
KFPFDFKC_00316	1235792.C808_04034	3.04e-104	310.0	COG1122@1|root,COG1122@2|Bacteria,1TSSM@1239|Firmicutes,249KS@186801|Clostridia,27KCE@186928|unclassified Lachnospiraceae	186801|Clostridia	P	AAA domain, putative AbiEii toxin, Type IV TA system	cbiO	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
KFPFDFKC_00317	457396.CSBG_01568	1.9e-92	280.0	COG0619@1|root,COG0619@2|Bacteria,1U6XW@1239|Firmicutes,24EV0@186801|Clostridia,36FJU@31979|Clostridiaceae	186801|Clostridia	P	Cobalt ABC transporter, permease	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
KFPFDFKC_00318	1280671.AUJH01000002_gene2226	1.05e-173	492.0	COG0310@1|root,COG0310@2|Bacteria,1TPEN@1239|Firmicutes,248S9@186801|Clostridia,4BW72@830|Butyrivibrio	186801|Clostridia	P	PDGLE domain	cbiM2	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
KFPFDFKC_00319	641107.CDLVIII_5672	1.41e-33	124.0	COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,248VX@186801|Clostridia,36DWD@31979|Clostridiaceae	186801|Clostridia	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
KFPFDFKC_00326	622312.ROSEINA2194_01333	7.74e-85	253.0	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,24MMK@186801|Clostridia	186801|Clostridia	S	Phosphoesterase	yfcE1	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
KFPFDFKC_00327	585394.RHOM_02950	1.12e-114	331.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
KFPFDFKC_00328	622312.ROSEINA2194_01335	2.14e-166	475.0	COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia	186801|Clostridia	M	PFAM cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,Cu_amine_oxidN1
KFPFDFKC_00329	622312.ROSEINA2194_01336	2.93e-316	872.0	COG4870@1|root,COG4870@2|Bacteria,1TVCW@1239|Firmicutes,248WA@186801|Clostridia	186801|Clostridia	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Cu_amine_oxidN1,Peptidase_C1,Rhodanese
KFPFDFKC_00330	585394.RHOM_02930	1.81e-258	711.0	COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,248MA@186801|Clostridia	186801|Clostridia	L	Belongs to the methyltransferase superfamily	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
KFPFDFKC_00331	585394.RHOM_02925	5.04e-37	127.0	COG0607@1|root,COG0607@2|Bacteria,1VGXK@1239|Firmicutes,24R46@186801|Clostridia	186801|Clostridia	P	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
KFPFDFKC_00333	585394.RHOM_02915	0.0	1103.0	COG0664@1|root,COG0664@2|Bacteria,1TSX5@1239|Firmicutes,24A8U@186801|Clostridia	186801|Clostridia	T	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
KFPFDFKC_00334	585394.RHOM_02910	2.52e-219	613.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,247J3@186801|Clostridia	186801|Clostridia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
KFPFDFKC_00340	397290.C810_04420	6.1e-135	388.0	COG0106@1|root,COG0106@2|Bacteria,1TPIN@1239|Firmicutes,249HJ@186801|Clostridia,27IKR@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Histidine biosynthesis protein	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
KFPFDFKC_00341	585394.RHOM_05285	9.35e-294	805.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia	186801|Clostridia	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
KFPFDFKC_00342	585394.RHOM_05290	6.15e-104	303.0	COG3707@1|root,COG3707@2|Bacteria,1V2S1@1239|Firmicutes,24EWG@186801|Clostridia	186801|Clostridia	K	ANTAR domain protein	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR
KFPFDFKC_00343	622312.ROSEINA2194_02823	4.32e-226	627.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
KFPFDFKC_00344	585394.RHOM_06195	2.54e-209	591.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
KFPFDFKC_00345	585394.RHOM_06200	9.99e-268	734.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia	186801|Clostridia	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
KFPFDFKC_00346	585394.RHOM_06205	5.55e-53	168.0	COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia	186801|Clostridia	U	Preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
KFPFDFKC_00347	397291.C804_00163	1.59e-33	132.0	2DY23@1|root,347RM@2|Bacteria,1VQMX@1239|Firmicutes,24UP2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00348	397291.C804_00162	1.7e-44	161.0	COG1396@1|root,COG1396@2|Bacteria,1VC2K@1239|Firmicutes,24NMY@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
KFPFDFKC_00350	203119.Cthe_0533	3.27e-118	360.0	COG0457@1|root,COG0535@1|root,COG0457@2|Bacteria,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,3WHA6@541000|Ruminococcaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
KFPFDFKC_00351	1211817.CCAT010000044_gene3366	2.24e-106	337.0	COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,248P6@186801|Clostridia,36FST@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
KFPFDFKC_00352	622312.ROSEINA2194_02817	3.74e-245	675.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia	186801|Clostridia	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
KFPFDFKC_00353	585394.RHOM_06225	0.0	1073.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia	186801|Clostridia	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
KFPFDFKC_00354	622312.ROSEINA2194_02815	0.0	957.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia	186801|Clostridia	H	Acetolactate synthase, large subunit	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
KFPFDFKC_00355	585394.RHOM_06235	2.21e-255	701.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia	186801|Clostridia	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
KFPFDFKC_00356	585394.RHOM_06240	3.37e-254	700.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia	186801|Clostridia	EH	D-isomer specific 2-hydroxyacid dehydrogenase	pdxB	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
KFPFDFKC_00357	585394.RHOM_06245	2.37e-238	662.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia	186801|Clostridia	S	Conserved protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
KFPFDFKC_00358	585394.RHOM_06250	9.28e-152	434.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,24CAG@186801|Clostridia	186801|Clostridia	M	mechanosensitive ion channel	mscS	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
KFPFDFKC_00359	585394.RHOM_06255	7.54e-40	132.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia	186801|Clostridia	K	Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
KFPFDFKC_00360	622312.ROSEINA2194_02811	0.0	1396.0	COG1026@1|root,COG1026@2|Bacteria,1TPD1@1239|Firmicutes	1239|Firmicutes	S	Peptidase M16 inactive domain protein	hypA2	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
KFPFDFKC_00361	622312.ROSEINA2194_02810	5.89e-203	563.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,24876@186801|Clostridia	186801|Clostridia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
KFPFDFKC_00363	585394.RHOM_06275	1.48e-124	361.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,249TI@186801|Clostridia	186801|Clostridia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
KFPFDFKC_00364	585394.RHOM_06280	5.23e-86	263.0	2BFV8@1|root,329QI@2|Bacteria,1V7DP@1239|Firmicutes,24KD4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00365	585394.RHOM_06285	0.0	958.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
KFPFDFKC_00366	622312.ROSEINA2194_02532	1.26e-138	416.0	28PI9@1|root,2ZC8C@2|Bacteria,1V36K@1239|Firmicutes,24K4U@186801|Clostridia	186801|Clostridia	S	Glucosyl transferase GtrII	-	-	-	-	-	-	-	-	-	-	-	-	Glucos_trans_II
KFPFDFKC_00368	411459.RUMOBE_02728	8.81e-193	584.0	COG4485@1|root,COG4485@2|Bacteria,1TPVY@1239|Firmicutes,24A98@186801|Clostridia,3Y056@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
KFPFDFKC_00369	1123313.ATUT01000016_gene618	2.73e-35	139.0	COG1835@1|root,COG1835@2|Bacteria,1UXXI@1239|Firmicutes,3VQ6J@526524|Erysipelotrichia	526524|Erysipelotrichia	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
KFPFDFKC_00370	585394.RHOM_04970	5.48e-218	606.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,247K2@186801|Clostridia	186801|Clostridia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
KFPFDFKC_00371	585394.RHOM_04975	4.32e-76	235.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
KFPFDFKC_00372	622312.ROSEINA2194_01132	0.0	1130.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
KFPFDFKC_00373	585394.RHOM_04985	6.03e-224	624.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
KFPFDFKC_00374	411462.DORLON_02785	2.4e-214	606.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,27VKG@189330|Dorea	186801|Clostridia	V	COG COG0534 Na -driven multidrug efflux pump	effD	-	-	-	-	-	-	-	-	-	-	-	MatE
KFPFDFKC_00375	622312.ROSEINA2194_00338	2.19e-136	394.0	2C6CR@1|root,2Z7X4@2|Bacteria,1UY2Y@1239|Firmicutes,24EJP@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_2
KFPFDFKC_00376	622312.ROSEINA2194_00337	8.55e-77	231.0	COG0735@1|root,COG0735@2|Bacteria,1V970@1239|Firmicutes,24QK7@186801|Clostridia	186801|Clostridia	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
KFPFDFKC_00377	585394.RHOM_05320	1.58e-176	501.0	COG0739@1|root,COG0739@2|Bacteria,1TQMQ@1239|Firmicutes,24B3J@186801|Clostridia	186801|Clostridia	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
KFPFDFKC_00378	585394.RHOM_05325	1.36e-202	583.0	COG2199@1|root,COG2984@1|root,COG2199@2|Bacteria,COG2984@2|Bacteria,1TS5J@1239|Firmicutes,25E4Y@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,GGDEF,PAS_3,PAS_9
KFPFDFKC_00379	585394.RHOM_05330	0.0	1159.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia	186801|Clostridia	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
KFPFDFKC_00380	622312.ROSEINA2194_00317	4.16e-137	389.0	COG0629@1|root,COG0629@2|Bacteria,1TRWZ@1239|Firmicutes,248UD@186801|Clostridia	186801|Clostridia	L	PFAM single-strand binding protein Primosomal replication protein n	ssb1	-	-	-	-	-	-	-	-	-	-	-	SSB
KFPFDFKC_00381	585394.RHOM_05340	5.15e-178	499.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia	186801|Clostridia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
KFPFDFKC_00382	585394.RHOM_05350	4.5e-150	426.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia	186801|Clostridia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17035	DapB_C,DapB_N
KFPFDFKC_00383	585394.RHOM_05355	0.0	1157.0	COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,248ZC@186801|Clostridia	186801|Clostridia	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3	fbp	-	3.1.3.11	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_2
KFPFDFKC_00384	585394.RHOM_05365	1.33e-158	449.0	COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,2499E@186801|Clostridia	186801|Clostridia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
KFPFDFKC_00385	585394.RHOM_05370	0.0	872.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia	186801|Clostridia	E	Orn Lys Arg decarboxylase major	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
KFPFDFKC_00386	585394.RHOM_05375	1.38e-191	533.0	COG0421@1|root,COG0421@2|Bacteria,1TPG5@1239|Firmicutes,24827@186801|Clostridia	186801|Clostridia	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
KFPFDFKC_00387	585394.RHOM_05380	3.63e-288	788.0	COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,24AHW@186801|Clostridia	186801|Clostridia	E	Saccharopine dehydrogenase	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
KFPFDFKC_00388	585394.RHOM_05385	3.86e-214	598.0	COG0019@1|root,COG0019@2|Bacteria,1TPQI@1239|Firmicutes,248NH@186801|Clostridia	186801|Clostridia	E	carboxynorspermidine decarboxylase	nspC	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_DAP_Arg_deC
KFPFDFKC_00389	585394.RHOM_05390	9.64e-179	510.0	COG2957@1|root,COG2957@2|Bacteria,1TQS5@1239|Firmicutes,248CP@186801|Clostridia	186801|Clostridia	E	agmatine deiminase	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
KFPFDFKC_00390	585394.RHOM_05395	1.49e-176	496.0	COG0388@1|root,COG0388@2|Bacteria,1TRMU@1239|Firmicutes,25B19@186801|Clostridia	186801|Clostridia	S	N-carbamoylputrescine amidase	aguB	-	3.5.1.53,3.5.1.6	ko:K01431,ko:K12251	ko00240,ko00330,ko00410,ko00770,ko00983,ko01100,map00240,map00330,map00410,map00770,map00983,map01100	M00046	R00905,R01152,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
KFPFDFKC_00391	585394.RHOM_11155	2.03e-227	628.0	COG2502@1|root,COG2502@2|Bacteria,1TP28@1239|Firmicutes,248S4@186801|Clostridia	186801|Clostridia	E	aspartate--ammonia ligase	asnA	-	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	-	AsnA
KFPFDFKC_00392	397290.C810_01607	4.47e-247	704.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,27IZ3@186928|unclassified Lachnospiraceae	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
KFPFDFKC_00393	585394.RHOM_11145	1.11e-142	412.0	COG1879@1|root,COG1879@2|Bacteria,1UYPR@1239|Firmicutes,248AW@186801|Clostridia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K17213	ko02010,map02010	M00593	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
KFPFDFKC_00394	397291.C804_05620	1.84e-74	228.0	COG3663@1|root,COG3663@2|Bacteria,1V6GI@1239|Firmicutes,24HD8@186801|Clostridia,27MP7@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
KFPFDFKC_00395	585394.RHOM_11135	1.95e-46	154.0	2C9RU@1|root,349H4@2|Bacteria,1VYXI@1239|Firmicutes,253A6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00396	622312.ROSEINA2194_03605	2.28e-159	447.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
KFPFDFKC_00397	585394.RHOM_07290	0.0	1190.0	COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,247QW@186801|Clostridia	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
KFPFDFKC_00398	1235793.C809_01000	4.13e-243	683.0	COG0488@1|root,COG0488@2|Bacteria,1TNYS@1239|Firmicutes,248D6@186801|Clostridia,27I99@186928|unclassified Lachnospiraceae	186801|Clostridia	S	ABC transporter	-	-	-	ko:K19350	ko02010,map02010	-	-	-	ko00000,ko00001,ko01504,ko02000	3.A.1.121	-	-	ABC_tran
KFPFDFKC_00400	622312.ROSEINA2194_02760	1.76e-131	382.0	COG0566@1|root,COG0566@2|Bacteria,1TSUW@1239|Firmicutes,24ACK@186801|Clostridia	186801|Clostridia	J	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
KFPFDFKC_00401	411468.CLOSCI_03722	1.3e-182	518.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,249SH@186801|Clostridia,21Y5G@1506553|Lachnoclostridium	186801|Clostridia	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
KFPFDFKC_00402	585394.RHOM_10150	0.0	1032.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia	186801|Clostridia	S	Abc transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
KFPFDFKC_00403	1235792.C808_03355	1.03e-75	227.0	COG1725@1|root,COG1725@2|Bacteria,1V9ZC@1239|Firmicutes,24NTW@186801|Clostridia,27MSR@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Bacterial regulatory proteins, gntR family	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
KFPFDFKC_00404	622312.ROSEINA2194_03083	1.61e-192	535.0	COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,247NW@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
KFPFDFKC_00405	622312.ROSEINA2194_03973	4.14e-131	373.0	2BVFM@1|root,320X7@2|Bacteria,1V984@1239|Firmicutes,24KKJ@186801|Clostridia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
KFPFDFKC_00406	411461.DORFOR_02251	1.89e-183	514.0	COG0826@1|root,COG0826@2|Bacteria,1TRX5@1239|Firmicutes,24CTG@186801|Clostridia,27W8Q@189330|Dorea	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00407	1280694.AUJQ01000006_gene775	2.25e-92	299.0	COG2199@1|root,COG2199@2|Bacteria,1V0N3@1239|Firmicutes,24FMU@186801|Clostridia,3NHV9@46205|Pseudobutyrivibrio	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GGDEF,SBP_bac_3
KFPFDFKC_00408	585394.RHOM_14880	1.3e-174	498.0	COG0738@1|root,COG0738@2|Bacteria,1TPB5@1239|Firmicutes,24913@186801|Clostridia	186801|Clostridia	G	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
KFPFDFKC_00409	411461.DORFOR_00452	3.33e-287	790.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,27UQI@189330|Dorea	186801|Clostridia	P	COG COG0733 Na -dependent transporters of the SNF family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
KFPFDFKC_00410	411469.EUBHAL_00026	0.0	971.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia,25UY4@186806|Eubacteriaceae	186801|Clostridia	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
KFPFDFKC_00411	585394.RHOM_10145	9.42e-242	674.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
KFPFDFKC_00412	411462.DORLON_01191	2.01e-116	343.0	COG0583@1|root,COG0583@2|Bacteria,1UXFR@1239|Firmicutes,25C6Q@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	ko:K21755	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
KFPFDFKC_00413	1227352.C173_28186	7.26e-59	191.0	COG2755@1|root,COG2755@2|Bacteria,1V1CQ@1239|Firmicutes,4HGVZ@91061|Bacilli,26WB3@186822|Paenibacillaceae	91061|Bacilli	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
KFPFDFKC_00414	585394.RHOM_16605	0.0	1348.0	COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,249IG@186801|Clostridia	186801|Clostridia	L	DNA helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,DUF4968,UvrD-helicase,UvrD_C,UvrD_C_2
KFPFDFKC_00415	1506994.JNLQ01000001_gene263	9.22e-146	416.0	COG2013@1|root,COG2013@2|Bacteria,1TP7N@1239|Firmicutes,249B4@186801|Clostridia,4BZ30@830|Butyrivibrio	186801|Clostridia	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
KFPFDFKC_00416	478749.BRYFOR_09858	1.85e-46	152.0	296XG@1|root,2ZU65@2|Bacteria,1V0MN@1239|Firmicutes,24GI1@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990
KFPFDFKC_00417	658655.HMPREF0988_01416	1.92e-71	218.0	2AUVQ@1|root,31KJ2@2|Bacteria,1V1UV@1239|Firmicutes,24H4A@186801|Clostridia,27MKJ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00418	1336241.JAEB01000004_gene516	2.97e-38	132.0	2AUVQ@1|root,2ZI4I@2|Bacteria,1V1YP@1239|Firmicutes,24FSR@186801|Clostridia,25W7C@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00419	1235798.C817_03921	1.04e-36	134.0	COG0582@1|root,COG0582@2|Bacteria,1TSQW@1239|Firmicutes,249T6@186801|Clostridia,27W47@189330|Dorea	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
KFPFDFKC_00420	1235793.C809_03547	2.18e-124	360.0	COG0500@1|root,COG2226@2|Bacteria,1TSAZ@1239|Firmicutes,2496P@186801|Clostridia,27JWR@186928|unclassified Lachnospiraceae	186801|Clostridia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
KFPFDFKC_00421	411463.EUBVEN_02876	5.96e-57	179.0	2C5R4@1|root,2ZC1N@2|Bacteria,1V292@1239|Firmicutes,25CQM@186801|Clostridia,25ZT4@186806|Eubacteriaceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
KFPFDFKC_00423	67267.JNXT01000092_gene5502	3.82e-15	87.4	COG2304@1|root,COG2304@2|Bacteria,2GKPD@201174|Actinobacteria	201174|Actinobacteria	E	IgA Peptidase M64	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M64
KFPFDFKC_00424	665950.HMPREF1025_00892	2.2e-123	364.0	COG1396@1|root,COG1396@2|Bacteria,1TQZJ@1239|Firmicutes,25E5Y@186801|Clostridia,27IYF@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
KFPFDFKC_00426	585394.RHOM_09595	1.06e-261	727.0	COG1158@1|root,COG1158@2|Bacteria,1TPHZ@1239|Firmicutes,247YK@186801|Clostridia	186801|Clostridia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
KFPFDFKC_00427	622312.ROSEINA2194_00129	1.98e-44	143.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia	186801|Clostridia	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
KFPFDFKC_00428	585394.RHOM_09585	1.03e-152	438.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,25C8E@186801|Clostridia	186801|Clostridia	J	Psort location CytoplasmicMembrane, score	prmC	-	-	-	-	-	-	-	-	-	-	-	DUF1385,MTS
KFPFDFKC_00429	585394.RHOM_09580	2.4e-158	448.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,24838@186801|Clostridia	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
KFPFDFKC_00430	622312.ROSEINA2194_00134	1.42e-229	635.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
KFPFDFKC_00431	411474.COPEUT_00843	4.09e-291	798.0	COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,247ZX@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
KFPFDFKC_00432	622312.ROSEINA2194_03508	0.0	1065.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,247Y0@186801|Clostridia	186801|Clostridia	J	Glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
KFPFDFKC_00433	585394.RHOM_05560	6.64e-147	420.0	COG1655@1|root,COG1655@2|Bacteria,1V2CM@1239|Firmicutes,25CK4@186801|Clostridia	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2225)	-	-	-	ko:K09766	-	-	-	-	ko00000	-	-	-	DUF2225
KFPFDFKC_00434	585394.RHOM_05565	1.39e-228	643.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia	186801|Clostridia	K	aminotransferase class I and II	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
KFPFDFKC_00435	1226325.HMPREF1548_00426	8.71e-90	269.0	28PR6@1|root,2ZCD4@2|Bacteria,1VRUS@1239|Firmicutes,25DRA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00436	658086.HMPREF0994_04643	4.49e-298	825.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,25CDM@186801|Clostridia,27RMB@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
KFPFDFKC_00437	1235800.C819_03159	2.33e-165	470.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,27QSG@186928|unclassified Lachnospiraceae	186801|Clostridia	EP	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
KFPFDFKC_00438	658086.HMPREF0994_04641	3.95e-151	435.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,27JBD@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
KFPFDFKC_00439	658086.HMPREF0994_04640	5.81e-189	529.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,27MDB@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
KFPFDFKC_00440	1226325.HMPREF1548_00432	4.62e-152	434.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,36E1E@31979|Clostridiaceae	186801|Clostridia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
KFPFDFKC_00441	1235800.C819_03155	5.21e-148	430.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,248AH@186801|Clostridia,27MED@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Peptidase dimerisation domain	-	-	-	ko:K01436,ko:K21613	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
KFPFDFKC_00442	585394.RHOM_05575	6.14e-298	812.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia	186801|Clostridia	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
KFPFDFKC_00443	622312.ROSEINA2194_04241	4.55e-243	669.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,247R3@186801|Clostridia	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
KFPFDFKC_00444	585394.RHOM_05585	1.94e-86	258.0	COG0454@1|root,COG0456@2|Bacteria,1V4GU@1239|Firmicutes,24IME@186801|Clostridia	186801|Clostridia	K	Acetyltransferase, gnat family	RimI	-	2.3.1.1	ko:K22477	ko00220,ko01210,ko01230,map00220,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
KFPFDFKC_00445	622312.ROSEINA2194_03939	4.13e-249	689.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
KFPFDFKC_00446	585394.RHOM_05595	1.95e-195	544.0	COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,2486J@186801|Clostridia	186801|Clostridia	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
KFPFDFKC_00447	585394.RHOM_05600	3.02e-246	681.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia	186801|Clostridia	E	PFAM Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
KFPFDFKC_00448	585394.RHOM_05605	1.06e-142	417.0	COG2182@1|root,COG2182@2|Bacteria,1V0VV@1239|Firmicutes,24E7F@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
KFPFDFKC_00449	622312.ROSEINA2194_03945	5.28e-51	171.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia	186801|Clostridia	L	TIGRFAM Competence protein ComEA, helix-hairpin-helix	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
KFPFDFKC_00450	585394.RHOM_05615	2.59e-161	452.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
KFPFDFKC_00451	585394.RHOM_05620	1.29e-273	757.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
KFPFDFKC_00452	585394.RHOM_05625	7.87e-161	459.0	COG5401@1|root,COG5401@2|Bacteria,1UXYS@1239|Firmicutes,24EK4@186801|Clostridia	186801|Clostridia	S	Sporulation and spore germination	-	-	-	ko:K06298	-	-	-	-	ko00000	-	-	-	Germane
KFPFDFKC_00453	585394.RHOM_05630	1.31e-181	549.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia	186801|Clostridia	M	Competence protein ComEC	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
KFPFDFKC_00454	622312.ROSEINA2194_03952	1.19e-187	526.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia	186801|Clostridia	L	DNA polymerase III (delta' subunit)	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
KFPFDFKC_00455	585394.RHOM_05640	1.11e-41	138.0	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia	186801|Clostridia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
KFPFDFKC_00456	585394.RHOM_05645	9e-184	518.0	COG0680@1|root,COG0680@2|Bacteria,1TPFY@1239|Firmicutes,248TE@186801|Clostridia	186801|Clostridia	C	Initiates the rapid degradation of small, acid-soluble proteins during spore germination	gpr	-	3.4.24.78	ko:K06012	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_A25
KFPFDFKC_00457	585394.RHOM_05650	1.37e-167	485.0	COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,2488U@186801|Clostridia	186801|Clostridia	M	stage II sporulation protein P	spoIIP	-	-	ko:K06385	-	-	-	-	ko00000	-	-	-	SpoIIP
KFPFDFKC_00458	585394.RHOM_05655	2.89e-78	238.0	COG0671@1|root,COG0671@2|Bacteria,1VB7J@1239|Firmicutes,24JDD@186801|Clostridia	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
KFPFDFKC_00459	622312.ROSEINA2194_03960	0.0	904.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,247YA@186801|Clostridia	186801|Clostridia	E	Asparagine synthase, glutamine-hydrolyzing	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
KFPFDFKC_00460	622312.ROSEINA2194_01813	1.38e-225	622.0	COG5464@1|root,COG5464@2|Bacteria,1UA0N@1239|Firmicutes,247X9@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
KFPFDFKC_00461	1540257.JQMW01000004_gene387	0.0	1172.0	COG0326@1|root,COG0326@2|Bacteria,1VDCC@1239|Firmicutes,25DU1@186801|Clostridia	186801|Clostridia	O	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_3
KFPFDFKC_00462	352165.HMPREF7215_0139	1.39e-49	171.0	COG2265@1|root,COG2265@2|Bacteria,3TAIZ@508458|Synergistetes	508458|Synergistetes	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
KFPFDFKC_00463	1280668.ATVT01000010_gene2212	8.46e-83	249.0	COG1670@1|root,COG1670@2|Bacteria,1V1T9@1239|Firmicutes,2498S@186801|Clostridia,4BWG4@830|Butyrivibrio	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
KFPFDFKC_00464	1392493.JIAB01000001_gene1004	7.13e-52	168.0	COG0454@1|root,COG0456@2|Bacteria,1V6P2@1239|Firmicutes,24NU3@186801|Clostridia	186801|Clostridia	K	Acetyltransferase, gnat family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
KFPFDFKC_00465	1392493.JIAB01000001_gene1001	4.83e-28	104.0	COG5566@1|root,COG5566@2|Bacteria,1VEZS@1239|Firmicutes,24QVB@186801|Clostridia,27PKY@186928|unclassified Lachnospiraceae	186801|Clostridia	S	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Mor
KFPFDFKC_00466	608534.GCWU000341_01822	9.51e-208	590.0	COG3039@1|root,COG3039@2|Bacteria,1TRUS@1239|Firmicutes,24AH8@186801|Clostridia,2PRYM@265975|Oribacterium	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2,DUF772
KFPFDFKC_00467	877424.ATWC01000011_gene1324	3.58e-82	245.0	COG1246@1|root,COG1246@2|Bacteria,1V4QW@1239|Firmicutes,24GCU@186801|Clostridia,27MPG@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_9,DUF2441
KFPFDFKC_00468	1392493.JIAB01000001_gene1255	1.11e-129	370.0	COG0237@1|root,COG0237@2|Bacteria,1VHNA@1239|Firmicutes,24KBU@186801|Clostridia,27KXQ@186928|unclassified Lachnospiraceae	186801|Clostridia	H	dephospho-CoA kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00469	1280680.AUJU01000031_gene3595	1.81e-99	294.0	COG0237@1|root,COG0237@2|Bacteria,1VHNA@1239|Firmicutes,24KBU@186801|Clostridia,4BW2U@830|Butyrivibrio	186801|Clostridia	H	dephospho-CoA kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00470	1280682.AUKA01000001_gene1844	9.95e-187	533.0	COG2207@1|root,COG2334@1|root,COG2207@2|Bacteria,COG2334@2|Bacteria,1TQGC@1239|Firmicutes,24B49@186801|Clostridia,4BYPK@830|Butyrivibrio	186801|Clostridia	K	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH,HTH_18
KFPFDFKC_00471	1280679.ATVX01000013_gene2555	1.66e-32	122.0	COG1349@1|root,COG1349@2|Bacteria,1UK7E@1239|Firmicutes,25FP5@186801|Clostridia	186801|Clostridia	GK	Replication initiator protein A (RepA) N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	RepA_N
KFPFDFKC_00472	1408324.JNJK01000035_gene2057	1.02e-09	58.5	296J0@1|root,2ZP02@2|Bacteria,1V4IJ@1239|Firmicutes,24HBP@186801|Clostridia,27Q3J@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
KFPFDFKC_00473	742765.HMPREF9457_02301	3.93e-190	531.0	COG3943@1|root,COG3943@2|Bacteria,1TPH4@1239|Firmicutes,248NI@186801|Clostridia,27W4A@189330|Dorea	186801|Clostridia	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_RhuM
KFPFDFKC_00474	742765.HMPREF9457_02300	0.0	1055.0	COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,25B03@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
KFPFDFKC_00475	1235790.C805_00291	2.52e-32	115.0	COG3077@1|root,COG3077@2|Bacteria,1VGJW@1239|Firmicutes,24R5Z@186801|Clostridia,25ZGQ@186806|Eubacteriaceae	186801|Clostridia	L	RelB antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	RelB
KFPFDFKC_00476	483218.BACPEC_01260	2.63e-52	166.0	COG3668@1|root,COG3668@2|Bacteria,1VFM7@1239|Firmicutes,24SXC@186801|Clostridia,26CEP@186813|unclassified Clostridiales	186801|Clostridia	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
KFPFDFKC_00478	1095750.HMPREF9970_2470	3.54e-38	130.0	COG4679@1|root,COG4679@2|Bacteria,1VB8K@1239|Firmicutes,25NMD@186801|Clostridia,1HWIY@1164882|Lachnoanaerobaculum	186801|Clostridia	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
KFPFDFKC_00479	180332.JTGN01000001_gene4600	1.13e-218	614.0	COG3547@1|root,COG3547@2|Bacteria,1TRSB@1239|Firmicutes,249AC@186801|Clostridia	186801|Clostridia	L	PFAM transposase IS116 IS110 IS902	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
KFPFDFKC_00480	1280685.AUKC01000006_gene1859	1.44e-52	166.0	COG3620@1|root,COG3620@2|Bacteria,1VH02@1239|Firmicutes,24Q0Q@186801|Clostridia,4BZUX@830|Butyrivibrio	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
KFPFDFKC_00482	478749.BRYFOR_05176	3.73e-218	615.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
KFPFDFKC_00483	622312.ROSEINA2194_00484	2.46e-210	615.0	COG0369@1|root,COG0534@1|root,COG0534@2|Bacteria,COG1151@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
KFPFDFKC_00484	585394.RHOM_02135	6.31e-134	387.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
KFPFDFKC_00485	483218.BACPEC_02964	7.13e-37	127.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,269QT@186813|unclassified Clostridiales	186801|Clostridia	O	Thioredoxin-like domain	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
KFPFDFKC_00486	585394.RHOM_02150	4.7e-82	244.0	COG1846@1|root,COG1846@2|Bacteria,1V6G0@1239|Firmicutes,24K11@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	ohrR	-	-	-	-	-	-	-	-	-	-	-	MarR
KFPFDFKC_00487	585394.RHOM_01250	6e-162	469.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
KFPFDFKC_00488	478749.BRYFOR_08058	1.93e-95	301.0	COG1396@1|root,COG1396@2|Bacteria,1VBK2@1239|Firmicutes,24N6F@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,TPR_8
KFPFDFKC_00489	478749.BRYFOR_08059	9.98e-190	540.0	COG0477@1|root,COG2814@2|Bacteria,1TZWA@1239|Firmicutes,24C48@186801|Clostridia	186801|Clostridia	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
KFPFDFKC_00490	622312.ROSEINA2194_01504	1.5e-215	603.0	COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,24825@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	5.1.1.1	ko:K01775,ko:K02529	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011,ko03000	-	-	-	LacI,Peripla_BP_3
KFPFDFKC_00491	622312.ROSEINA2194_01505	1.13e-296	817.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia	186801|Clostridia	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
KFPFDFKC_00492	622312.ROSEINA2194_01506	2.54e-242	674.0	COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia	186801|Clostridia	G	ABC transporter, solute-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
KFPFDFKC_00493	622312.ROSEINA2194_01507	2.68e-294	807.0	COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,247MA@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
KFPFDFKC_00494	622312.ROSEINA2194_01508	9.81e-179	501.0	COG3833@1|root,COG3833@2|Bacteria,1TRB7@1239|Firmicutes,248A7@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
KFPFDFKC_00495	622312.ROSEINA2194_01509	1.03e-285	796.0	COG0366@1|root,COG0366@2|Bacteria,1TSEA@1239|Firmicutes,248HJ@186801|Clostridia	186801|Clostridia	G	Alpha amylase catalytic	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459
KFPFDFKC_00496	585394.RHOM_12765	7.83e-79	242.0	2E401@1|root,32YWY@2|Bacteria,1V9X1@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00497	1163671.JAGI01000002_gene987	3.64e-32	121.0	COG1309@1|root,COG1309@2|Bacteria,1VGKF@1239|Firmicutes,25BTR@186801|Clostridia,36JX9@31979|Clostridiaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
KFPFDFKC_00498	1216932.CM240_1762	0.000785	50.1	COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,247R6@186801|Clostridia,36DHN@31979|Clostridiaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
KFPFDFKC_00501	622312.ROSEINA2194_01515	0.0	926.0	COG3408@1|root,COG3408@2|Bacteria,1TPX8@1239|Firmicutes,249BI@186801|Clostridia	186801|Clostridia	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
KFPFDFKC_00502	140626.JHWB01000009_gene1666	7.79e-30	114.0	2E823@1|root,332G5@2|Bacteria,1VRKM@1239|Firmicutes,24FQ4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00503	622312.ROSEINA2194_01517	3.78e-143	407.0	COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,2489I@186801|Clostridia	186801|Clostridia	O	FeS assembly ATPase SufC	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
KFPFDFKC_00504	622312.ROSEINA2194_01518	5.74e-205	569.0	COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,249IU@186801|Clostridia	186801|Clostridia	O	feS assembly protein SufB	-	-	-	ko:K07033	-	-	-	-	ko00000	-	-	-	UPF0051
KFPFDFKC_00505	1280681.AUJZ01000012_gene1135	5.61e-19	82.8	2ED22@1|root,2ZVQM@2|Bacteria,1W3EW@1239|Firmicutes,256YE@186801|Clostridia,4BZ46@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00506	585394.RHOM_02440	5.61e-98	288.0	COG1451@1|root,COG1451@2|Bacteria,1UJII@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
KFPFDFKC_00507	411474.COPEUT_02877	8.21e-17	73.6	2EG1V@1|root,339TV@2|Bacteria,1VKAZ@1239|Firmicutes,24UGV@186801|Clostridia	186801|Clostridia	S	COG NOG17973 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF4250
KFPFDFKC_00509	585394.RHOM_02455	1.51e-35	120.0	2EGE3@1|root,33A60@2|Bacteria,1VMF7@1239|Firmicutes,24UMV@186801|Clostridia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00510	1408306.JHXX01000009_gene3377	2.35e-94	291.0	COG0860@1|root,COG0860@2|Bacteria,1UY5Q@1239|Firmicutes,247Y6@186801|Clostridia,4BWSH@830|Butyrivibrio	186801|Clostridia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
KFPFDFKC_00511	585394.RHOM_02460	0.0	1011.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
KFPFDFKC_00512	585394.RHOM_02465	0.0	1093.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
KFPFDFKC_00513	585394.RHOM_02470	0.0	1096.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
KFPFDFKC_00514	585394.RHOM_02475	2.69e-207	575.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,24999@186801|Clostridia	186801|Clostridia	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
KFPFDFKC_00515	585394.RHOM_02480	4.52e-301	825.0	COG1362@1|root,COG1362@2|Bacteria,1TP6G@1239|Firmicutes,2486Y@186801|Clostridia	186801|Clostridia	E	M18 family aminopeptidase	apeA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M18
KFPFDFKC_00516	585394.RHOM_02485	3.53e-137	397.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
KFPFDFKC_00517	585394.RHOM_02490	4.44e-179	502.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
KFPFDFKC_00518	622312.ROSEINA2194_03472	6.05e-145	416.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,2484M@186801|Clostridia	186801|Clostridia	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
KFPFDFKC_00519	585394.RHOM_02500	4.51e-30	108.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsH	-	-	ko:K11184,ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
KFPFDFKC_00520	585394.RHOM_02505	4.42e-181	508.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,249SY@186801|Clostridia	186801|Clostridia	I	lipid kinase, YegS Rv2252 BmrU family	dagK	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
KFPFDFKC_00521	585394.RHOM_02510	1.4e-201	558.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia	186801|Clostridia	G	Fructose-1,6-bisphosphate aldolase, class II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
KFPFDFKC_00522	585394.RHOM_02515	0.0	1234.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia	186801|Clostridia	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
KFPFDFKC_00523	585394.RHOM_02520	9.27e-66	201.0	COG0347@1|root,COG0347@2|Bacteria,1V9Z5@1239|Firmicutes,24MNA@186801|Clostridia	186801|Clostridia	K	Belongs to the P(II) protein family	glnB1	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
KFPFDFKC_00524	585394.RHOM_02525	3.07e-283	774.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,247W1@186801|Clostridia	186801|Clostridia	P	Ammonium Transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,P-II
KFPFDFKC_00525	742765.HMPREF9457_03704	8.59e-32	115.0	COG1708@1|root,COG1708@2|Bacteria,1UKQY@1239|Firmicutes,25G1K@186801|Clostridia	186801|Clostridia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
KFPFDFKC_00526	877421.AUJT01000008_gene2695	1.51e-49	160.0	COG1669@1|root,COG1669@2|Bacteria,1VBZU@1239|Firmicutes,24VNT@186801|Clostridia,27PBK@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
KFPFDFKC_00527	1408423.JHYA01000005_gene1804	2.03e-45	149.0	COG1895@1|root,COG1895@2|Bacteria,1VI2F@1239|Firmicutes,4H8HF@909932|Negativicutes	909932|Negativicutes	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
KFPFDFKC_00528	1095750.HMPREF9970_1658	1.51e-97	306.0	COG5044@1|root,COG5044@2|Bacteria,1VXKX@1239|Firmicutes,252J9@186801|Clostridia	186801|Clostridia	O	Rab GDP-dissociation inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00529	1095750.HMPREF9970_1659	8.27e-289	866.0	COG0515@1|root,COG3903@1|root,COG0515@2|Bacteria,COG3903@2|Bacteria,1TY16@1239|Firmicutes,24A3H@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,Pkinase
KFPFDFKC_00532	556261.HMPREF0240_04096	1.23e-16	75.1	COG5566@1|root,COG5566@2|Bacteria,1VK7Y@1239|Firmicutes,24SS6@186801|Clostridia,36MMH@31979|Clostridiaceae	186801|Clostridia	S	Mor transcription activator family	-	-	-	-	-	-	-	-	-	-	-	-	Mor
KFPFDFKC_00533	411483.FAEPRAA2165_02657	8.46e-49	162.0	COG3597@1|root,COG3597@2|Bacteria,1TSZW@1239|Firmicutes,249YT@186801|Clostridia,3WKSA@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF697,MMR_HSR1
KFPFDFKC_00534	397287.C807_03073	1.23e-12	62.4	2EIY3@1|root,33CP9@2|Bacteria,1VN11@1239|Firmicutes,24W71@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00536	585394.RHOM_02535	0.0	1372.0	COG5009@1|root,COG5009@2|Bacteria,1UI0H@1239|Firmicutes,25E95@186801|Clostridia	186801|Clostridia	M	penicillin-binding protein	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
KFPFDFKC_00537	585394.RHOM_02540	6.8e-124	356.0	COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,248W7@186801|Clostridia	186801|Clostridia	S	YigZ family	yvyE	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
KFPFDFKC_00539	622312.ROSEINA2194_01571	5.63e-102	303.0	COG3884@1|root,COG3884@2|Bacteria,1TRH5@1239|Firmicutes,24G5K@186801|Clostridia	186801|Clostridia	I	Acyl-ACP thioesterase	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Acyl-ACP_TE
KFPFDFKC_00540	585394.RHOM_02550	1.31e-158	449.0	COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,2498C@186801|Clostridia	186801|Clostridia	S	S1, RNA binding domain	cvfB	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1,S1_2
KFPFDFKC_00541	585394.RHOM_02555	3.88e-75	225.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia	186801|Clostridia	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
KFPFDFKC_00542	592026.GCWU0000282_001066	1.87e-06	47.8	2EI20@1|root,33BTH@2|Bacteria,1VQF2@1239|Firmicutes	1239|Firmicutes	S	Putative motility protein	-	-	-	-	-	-	-	-	-	-	-	-	YjfB_motility
KFPFDFKC_00543	585394.RHOM_02570	2.33e-159	460.0	COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG4991@2|Bacteria,1TRKG@1239|Firmicutes,249Y4@186801|Clostridia	186801|Clostridia	MT	NlpC p60 family protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3
KFPFDFKC_00544	585394.RHOM_14870	0.0	935.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,248DZ@186801|Clostridia	186801|Clostridia	T	carbon starvation protein CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
KFPFDFKC_00545	585394.RHOM_02575	8.72e-82	251.0	COG1922@1|root,COG1922@2|Bacteria,1V7RM@1239|Firmicutes,24HC8@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
KFPFDFKC_00546	622312.ROSEINA2194_01579	1.27e-141	407.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,25CBM@186801|Clostridia	186801|Clostridia	S	protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
KFPFDFKC_00547	585394.RHOM_02580	3.34e-246	677.0	COG2508@1|root,COG2508@2|Bacteria,1TTA0@1239|Firmicutes,248HN@186801|Clostridia	186801|Clostridia	QT	Psort location Cytoplasmic, score	cdaR_3	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30
KFPFDFKC_00548	585394.RHOM_02585	5.81e-139	397.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia	186801|Clostridia	D	cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
KFPFDFKC_00549	622312.ROSEINA2194_01582	1.05e-173	489.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,24AA6@186801|Clostridia	186801|Clostridia	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
KFPFDFKC_00550	585394.RHOM_02595	9.36e-134	397.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia	186801|Clostridia	D	Peptidase, M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
KFPFDFKC_00551	622312.ROSEINA2194_01585	5.21e-217	609.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia	186801|Clostridia	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
KFPFDFKC_00552	622312.ROSEINA2194_01586	2.34e-46	155.0	COG5652@1|root,COG5652@2|Bacteria,1VF6Q@1239|Firmicutes,24QQ8@186801|Clostridia	186801|Clostridia	S	PFAM VanZ family protein	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
KFPFDFKC_00553	585394.RHOM_02610	7.05e-227	627.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,247KU@186801|Clostridia	186801|Clostridia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
KFPFDFKC_00554	1408323.JQKK01000025_gene1380	1.44e-70	224.0	2EN4B@1|root,33FSE@2|Bacteria,1VPF9@1239|Firmicutes,24SXK@186801|Clostridia,27NCJ@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Tim44,zinc_ribbon_2
KFPFDFKC_00555	585394.RHOM_02620	2.79e-211	596.0	COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia	186801|Clostridia	L	virion core protein (lumpy skin disease virus)	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1
KFPFDFKC_00556	585394.RHOM_02625	1.64e-160	462.0	COG1645@1|root,COG1645@2|Bacteria,1TRYG@1239|Firmicutes,25F3V@186801|Clostridia	186801|Clostridia	S	bacterial-type flagellum-dependent swarming motility	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00557	585394.RHOM_02630	3.29e-42	153.0	COG1512@1|root,COG1512@2|Bacteria,1V8N5@1239|Firmicutes,24H2W@186801|Clostridia	186801|Clostridia	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
KFPFDFKC_00558	585394.RHOM_02635	2.15e-83	248.0	COG4492@1|root,COG4492@2|Bacteria,1VAJ9@1239|Firmicutes,24MTS@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0735 family	pheB	-	5.4.99.5	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4
KFPFDFKC_00559	622312.ROSEINA2194_01595	5.23e-237	657.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia	186801|Clostridia	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
KFPFDFKC_00560	658086.HMPREF0994_00444	5.94e-29	108.0	COG2198@1|root,COG2198@2|Bacteria,1VG8R@1239|Firmicutes,24JZF@186801|Clostridia,27PU8@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Hpt domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
KFPFDFKC_00561	585394.RHOM_02670	2.54e-73	227.0	COG1971@1|root,COG1971@2|Bacteria,1V25U@1239|Firmicutes	1239|Firmicutes	P	Probably functions as a manganese efflux pump	ytaF	-	-	-	-	-	-	-	-	-	-	-	Mntp
KFPFDFKC_00562	622312.ROSEINA2194_01607	6.33e-242	666.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia	186801|Clostridia	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
KFPFDFKC_00563	585394.RHOM_02740	0.0	2013.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia	186801|Clostridia	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS
KFPFDFKC_00564	585394.RHOM_02755	7.79e-209	589.0	COG2206@1|root,COG2206@2|Bacteria,1UUCI@1239|Firmicutes,24CPS@186801|Clostridia	186801|Clostridia	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
KFPFDFKC_00565	585394.RHOM_02760	9.46e-90	282.0	COG3773@1|root,COG3883@1|root,COG3773@2|Bacteria,COG3883@2|Bacteria,1V02Q@1239|Firmicutes,24CZW@186801|Clostridia	186801|Clostridia	M	Cell wall hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_2
KFPFDFKC_00566	622312.ROSEINA2194_04078	1.26e-268	737.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia	186801|Clostridia	I	Belongs to the thiolase family	thlA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
KFPFDFKC_00567	585394.RHOM_02770	2.14e-199	553.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
KFPFDFKC_00568	585394.RHOM_02775	4.52e-262	719.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia	186801|Clostridia	C	acyl-CoA dehydrogenase	bcd	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
KFPFDFKC_00569	622312.ROSEINA2194_04075	2.29e-179	500.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia	186801|Clostridia	C	electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
KFPFDFKC_00570	622312.ROSEINA2194_04074	1.41e-240	662.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia	186801|Clostridia	C	electron transfer flavoprotein	etfA	-	1.3.1.108	ko:K03522,ko:K22432	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	ETF,ETF_alpha
KFPFDFKC_00571	1384066.JAGT01000001_gene2174	2.38e-15	78.6	COG3291@1|root,COG4412@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria,1TTH2@1239|Firmicutes,258XS@186801|Clostridia,3WP03@541000|Ruminococcaceae	186801|Clostridia	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00572	1408324.JNJK01000020_gene3693	7.35e-10	60.8	COG4412@1|root,COG4412@2|Bacteria,1VJS1@1239|Firmicutes,24RVX@186801|Clostridia,27QA4@186928|unclassified Lachnospiraceae	186801|Clostridia	S	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00573	622312.ROSEINA2194_00831	1.85e-91	273.0	COG4684@1|root,COG4684@2|Bacteria,1V2ZW@1239|Firmicutes	1239|Firmicutes	S	ECF transporter, substrate-specific component	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
KFPFDFKC_00574	622312.ROSEINA2194_00831	1.15e-97	290.0	COG4684@1|root,COG4684@2|Bacteria,1V2ZW@1239|Firmicutes	1239|Firmicutes	S	ECF transporter, substrate-specific component	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
KFPFDFKC_00575	411462.DORLON_02376	2.08e-42	150.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,27WEW@189330|Dorea	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
KFPFDFKC_00576	742765.HMPREF9457_00198	3.54e-88	269.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,27WEW@189330|Dorea	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
KFPFDFKC_00577	411462.DORLON_02377	3.84e-72	248.0	COG3976@1|root,COG3976@2|Bacteria,1TR5A@1239|Firmicutes,25E6J@186801|Clostridia,27VY2@189330|Dorea	186801|Clostridia	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,Fer4_5
KFPFDFKC_00578	742765.HMPREF9457_00196	2.29e-39	136.0	COG3976@1|root,COG3976@2|Bacteria,1VENM@1239|Firmicutes,24RRX@186801|Clostridia,27WZB@189330|Dorea	186801|Clostridia	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
KFPFDFKC_00579	742765.HMPREF9457_00195	3.41e-38	140.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,27WG2@189330|Dorea	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
KFPFDFKC_00580	1280698.AUJS01000027_gene2309	5.58e-135	426.0	COG1196@1|root,COG1196@2|Bacteria,1UJ26@1239|Firmicutes,25EV1@186801|Clostridia,27WJD@189330|Dorea	186801|Clostridia	D	Penicillin-binding protein Tp47 domain a	-	-	-	-	-	-	-	-	-	-	-	-	DUF1533,FIVAR,FMN_bind,PBP-Tp47_a,PBP-Tp47_c
KFPFDFKC_00581	1410628.JNKS01000007_gene1428	7.76e-13	68.2	2BZT8@1|root,32W5F@2|Bacteria,1UGQC@1239|Firmicutes,24Q23@186801|Clostridia,27RY9@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
KFPFDFKC_00583	585394.RHOM_13050	4.08e-43	140.0	COG1609@1|root,COG1609@2|Bacteria,1VADF@1239|Firmicutes,24MXI@186801|Clostridia	186801|Clostridia	K	sporulation transcriptional regulator SpoIIID	spoIIID	-	-	ko:K06283	-	-	-	-	ko00000,ko03000	-	-	-	SpoIIID
KFPFDFKC_00584	622312.ROSEINA2194_00215	1.8e-103	301.0	2CAVT@1|root,304CC@2|Bacteria,1V4J6@1239|Firmicutes,24HQA@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2798
KFPFDFKC_00586	622312.ROSEINA2194_00211	0.0	969.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia	186801|Clostridia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
KFPFDFKC_00587	500632.CLONEX_00864	1.43e-298	815.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
KFPFDFKC_00588	483218.BACPEC_02841	5.87e-126	359.0	COG1396@1|root,COG1396@2|Bacteria,1V9ZU@1239|Firmicutes,25PFH@186801|Clostridia,26CEE@186813|unclassified Clostridiales	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
KFPFDFKC_00590	411489.CLOL250_02627	3.08e-314	863.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,36DX4@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
KFPFDFKC_00591	585394.RHOM_15670	1.7e-93	275.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
KFPFDFKC_00592	622312.ROSEINA2194_00784	4.33e-54	177.0	2ECHQ@1|root,336FZ@2|Bacteria,1VI4C@1239|Firmicutes,24TFT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00593	622312.ROSEINA2194_00783	1.72e-203	566.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia	186801|Clostridia	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
KFPFDFKC_00594	585394.RHOM_15685	3.19e-169	474.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia	186801|Clostridia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
KFPFDFKC_00595	585394.RHOM_15690	4.83e-60	186.0	2CJXG@1|root,32SB0@2|Bacteria,1VAFJ@1239|Firmicutes,24MNI@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00596	622312.ROSEINA2194_00780	6.6e-177	499.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia	186801|Clostridia	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
KFPFDFKC_00597	585394.RHOM_15700	2e-219	607.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia	186801|Clostridia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
KFPFDFKC_00598	622312.ROSEINA2194_00777	1.13e-127	375.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia	186801|Clostridia	O	SPFH Band 7 PHB domain protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
KFPFDFKC_00599	585394.RHOM_14185	1.09e-117	348.0	COG0392@1|root,COG0392@2|Bacteria,1V2TI@1239|Firmicutes,24K1U@186801|Clostridia	186801|Clostridia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
KFPFDFKC_00600	622312.ROSEINA2194_04045	0.0	916.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
KFPFDFKC_00601	585394.RHOM_14195	1.05e-148	427.0	COG0770@1|root,COG0770@2|Bacteria,1TS8M@1239|Firmicutes,24CJW@186801|Clostridia	186801|Clostridia	M	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
KFPFDFKC_00602	585394.RHOM_14200	5.37e-186	521.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,248UR@186801|Clostridia	186801|Clostridia	CH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
KFPFDFKC_00603	585394.RHOM_14205	4.33e-154	438.0	COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,2485C@186801|Clostridia	186801|Clostridia	S	Phospholipase, patatin family	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
KFPFDFKC_00604	622312.ROSEINA2194_04052	1.76e-61	193.0	COG1585@1|root,COG1585@2|Bacteria,1VAS9@1239|Firmicutes,24MRQ@186801|Clostridia	186801|Clostridia	OU	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
KFPFDFKC_00605	585394.RHOM_14215	4.18e-56	186.0	2DU28@1|root,33NME@2|Bacteria,1VMV6@1239|Firmicutes,24V3C@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00606	585394.RHOM_14220	9.72e-195	547.0	COG1619@1|root,COG1619@2|Bacteria,1TZSN@1239|Firmicutes,25CIH@186801|Clostridia	186801|Clostridia	V	proteins homologs of microcin C7 resistance protein MccF	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S66
KFPFDFKC_00609	1139219.I569_00581	9.04e-58	196.0	28IGH@1|root,2Z8HY@2|Bacteria,1TQX2@1239|Firmicutes,4HA00@91061|Bacilli,4AZ8X@81852|Enterococcaceae	91061|Bacilli	S	Conjugative transposon protein TcpC	-	-	-	-	-	-	-	-	-	-	-	-	TpcC
KFPFDFKC_00611	641107.CDLVIII_5796	4.97e-122	361.0	COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia,36H24@31979|Clostridiaceae	186801|Clostridia	M	NlpC P60 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Lysozyme_like,NLPC_P60
KFPFDFKC_00612	908340.HMPREF9406_0793	4.16e-145	453.0	COG3064@1|root,COG3064@2|Bacteria,1UIYZ@1239|Firmicutes,249MX@186801|Clostridia,36FMM@31979|Clostridiaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00613	1158601.I585_00435	0.0	978.0	COG0433@1|root,COG0433@2|Bacteria,1TPVQ@1239|Firmicutes,4HBZY@91061|Bacilli,4B0FA@81852|Enterococcaceae	91061|Bacilli	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
KFPFDFKC_00614	658659.HMPREF0983_03979	3.95e-36	127.0	28I70@1|root,2Z89W@2|Bacteria,1V1TC@1239|Firmicutes,3VQEW@526524|Erysipelotrichia	1239|Firmicutes	S	TcpE family	-	-	-	-	-	-	-	-	-	-	-	-	TcpE
KFPFDFKC_00616	1121090.KB894686_gene2838	1.69e-148	438.0	COG3620@1|root,COG3620@2|Bacteria,1TPHQ@1239|Firmicutes,4HCHD@91061|Bacilli,1ZSHH@1386|Bacillus	91061|Bacilli	K	Replication initiation factor	-	-	-	ko:K07467	-	-	-	-	ko00000	-	-	-	HTH_3,Omega_Repress,Rep_trans
KFPFDFKC_00618	411461.DORFOR_03093	9.71e-133	397.0	COG1674@1|root,COG1674@2|Bacteria,1TPHE@1239|Firmicutes,249WR@186801|Clostridia,27V96@189330|Dorea	186801|Clostridia	D	COG COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF87,FtsK_SpoIIIE
KFPFDFKC_00620	471875.RUMLAC_01418	3.59e-33	118.0	2BXTH@1|root,2ZZ52@2|Bacteria,1V3TU@1239|Firmicutes,24I3V@186801|Clostridia,3WJS5@541000|Ruminococcaceae	186801|Clostridia	S	Bacterial protein of unknown function (DUF961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF961
KFPFDFKC_00629	742733.HMPREF9469_02677	1.01e-06	48.5	2ECXB@1|root,336UH@2|Bacteria,1VJWZ@1239|Firmicutes,24UVH@186801|Clostridia	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
KFPFDFKC_00630	592026.GCWU0000282_000988	3.11e-34	118.0	COG3514@1|root,COG3514@2|Bacteria,1VFWT@1239|Firmicutes,24S45@186801|Clostridia	186801|Clostridia	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
KFPFDFKC_00631	246199.CUS_5631	4.61e-45	147.0	COG2929@1|root,COG2929@2|Bacteria,1VE89@1239|Firmicutes,24N45@186801|Clostridia	186801|Clostridia	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnT_toxin
KFPFDFKC_00632	585394.RHOM_05265	2.15e-84	280.0	2C4YK@1|root,342PE@2|Bacteria,1VWY9@1239|Firmicutes,24TZZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00634	397288.C806_01801	1.38e-14	85.5	COG5492@1|root,COG5492@2|Bacteria,1UDEG@1239|Firmicutes,25I43@186801|Clostridia,27RQX@186928|unclassified Lachnospiraceae	186801|Clostridia	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
KFPFDFKC_00640	585394.RHOM_05235	1.04e-14	71.6	2EG0W@1|root,339SX@2|Bacteria,1VKDR@1239|Firmicutes,24S7Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00641	585394.RHOM_05230	3.24e-135	407.0	28I5Y@1|root,2Z892@2|Bacteria,1UYUF@1239|Firmicutes,24CM9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00642	585394.RHOM_05225	5.15e-91	276.0	COG0630@1|root,COG0630@2|Bacteria,1UHT2@1239|Firmicutes,25EN1@186801|Clostridia	186801|Clostridia	NU	COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
KFPFDFKC_00643	585394.RHOM_05225	5.05e-65	211.0	COG0630@1|root,COG0630@2|Bacteria,1UHT2@1239|Firmicutes,25EN1@186801|Clostridia	186801|Clostridia	NU	COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
KFPFDFKC_00653	1462527.CCDM010000002_gene1665	3.73e-22	94.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
KFPFDFKC_00655	476272.RUMHYD_02827	1.53e-20	83.6	COG1974@1|root,COG1974@2|Bacteria	2|Bacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	HTH_3,LexA_DNA_bind,Peptidase_S24
KFPFDFKC_00656	476272.RUMHYD_02826	2.57e-35	125.0	COG1476@1|root,COG1476@2|Bacteria,1VGN2@1239|Firmicutes,24T4H@186801|Clostridia	186801|Clostridia	K	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00657	476272.RUMHYD_02826	1.62e-53	171.0	COG1476@1|root,COG1476@2|Bacteria,1VGN2@1239|Firmicutes,24T4H@186801|Clostridia	186801|Clostridia	K	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00659	411468.CLOSCI_00325	1.23e-89	282.0	COG0582@1|root,COG0582@2|Bacteria,1V16B@1239|Firmicutes,24CY2@186801|Clostridia,221KI@1506553|Lachnoclostridium	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
KFPFDFKC_00660	140626.JHWB01000022_gene2115	1.57e-98	291.0	COG1011@1|root,COG1011@2|Bacteria,1V6I4@1239|Firmicutes,24JK7@186801|Clostridia	186801|Clostridia	S	HAD hydrolase, family IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
KFPFDFKC_00661	585394.RHOM_14265	1.39e-218	633.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
KFPFDFKC_00662	1256908.HMPREF0373_02016	1.54e-144	412.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,25V99@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
KFPFDFKC_00663	585394.RHOM_14275	1.95e-102	312.0	COG0642@1|root,COG0642@2|Bacteria,1TQSG@1239|Firmicutes,25EB7@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
KFPFDFKC_00664	1235793.C809_02063	6.44e-123	354.0	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,249TG@186801|Clostridia,27IZY@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	graR	-	-	ko:K19082	ko02020,map02020	M00734,M00737	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
KFPFDFKC_00665	585394.RHOM_14285	6.01e-226	625.0	COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes,24842@186801|Clostridia	186801|Clostridia	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
KFPFDFKC_00666	585394.RHOM_15710	1.23e-142	423.0	COG3103@1|root,COG3773@1|root,COG3103@2|Bacteria,COG3773@2|Bacteria,1TRFW@1239|Firmicutes,24DDK@186801|Clostridia	186801|Clostridia	MT	Cell Wall Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_2,SH3_3
KFPFDFKC_00668	585394.RHOM_15725	1.15e-211	590.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
KFPFDFKC_00669	622312.ROSEINA2194_00772	3.52e-85	252.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia	186801|Clostridia	FG	PFAM Histidine triad (HIT) protein	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
KFPFDFKC_00670	585394.RHOM_15740	2.5e-200	559.0	COG0655@1|root,COG3255@1|root,COG0655@2|Bacteria,COG3255@2|Bacteria,1TT0Y@1239|Firmicutes,247MH@186801|Clostridia	186801|Clostridia	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
KFPFDFKC_00671	622312.ROSEINA2194_00769	1.22e-155	447.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,247PT@186801|Clostridia	186801|Clostridia	S	PFAM Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
KFPFDFKC_00672	585394.RHOM_15750	5.72e-74	241.0	COG1716@1|root,COG1716@2|Bacteria,1V550@1239|Firmicutes,24BVK@186801|Clostridia	186801|Clostridia	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
KFPFDFKC_00675	622312.ROSEINA2194_00764	7.03e-69	221.0	COG4961@1|root,COG4961@2|Bacteria,1V9E1@1239|Firmicutes,24ET0@186801|Clostridia	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TadE
KFPFDFKC_00676	585394.RHOM_15770	3.63e-105	330.0	2BXNJ@1|root,2ZC8M@2|Bacteria,1UYM5@1239|Firmicutes,24ASZ@186801|Clostridia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00677	397287.C807_03605	8.06e-11	58.2	2EHSI@1|root,33BI9@2|Bacteria,1VK7K@1239|Firmicutes,24UF9@186801|Clostridia,27QCR@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Putative Flagellin, Flp1-like, domain	-	-	-	-	-	-	-	-	-	-	-	-	Flp1_like
KFPFDFKC_00678	622312.ROSEINA2194_00761	4.84e-94	296.0	COG2064@1|root,COG2064@2|Bacteria,1V2C3@1239|Firmicutes,24AN4@186801|Clostridia	186801|Clostridia	NU	Psort location CytoplasmicMembrane, score	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
KFPFDFKC_00679	585394.RHOM_15785	9.39e-78	241.0	COG4965@1|root,COG4965@2|Bacteria,1V6PB@1239|Firmicutes,24JBR@186801|Clostridia	186801|Clostridia	U	Psort location CytoplasmicMembrane, score	tadB	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
KFPFDFKC_00680	585394.RHOM_15790	1.29e-195	554.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia	186801|Clostridia	U	Type II IV secretion system protein	ptlH	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
KFPFDFKC_00681	585394.RHOM_15795	9.43e-93	287.0	COG1192@1|root,COG1192@2|Bacteria,1V11K@1239|Firmicutes,24FDX@186801|Clostridia	186801|Clostridia	D	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
KFPFDFKC_00682	585394.RHOM_15800	1.64e-52	170.0	2EHCT@1|root,33B4M@2|Bacteria,1UPNG@1239|Firmicutes	1239|Firmicutes	S	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
KFPFDFKC_00684	1235790.C805_03392	5.65e-22	88.2	2EIA7@1|root,33C1J@2|Bacteria,1VMCK@1239|Firmicutes,24W47@186801|Clostridia,25XQS@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF2508)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2508
KFPFDFKC_00685	622312.ROSEINA2194_00755	1.22e-69	214.0	COG1516@1|root,COG1516@2|Bacteria,1VD1Q@1239|Firmicutes,24PMH@186801|Clostridia	186801|Clostridia	NOU	Flagellar protein FliS	-	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
KFPFDFKC_00686	585394.RHOM_15820	3.83e-199	570.0	COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia	186801|Clostridia	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	hag	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
KFPFDFKC_00687	585394.RHOM_15825	7.4e-41	134.0	COG2846@1|root,COG2846@2|Bacteria,1VET8@1239|Firmicutes,24QPY@186801|Clostridia	186801|Clostridia	D	cluster protein-associated redox disulfide domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858
KFPFDFKC_00688	585394.RHOM_15830	6.8e-127	368.0	COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,24BWV@186801|Clostridia	186801|Clostridia	NOT	Negative regulator of genetic competence	mecB	-	-	ko:K16511	-	-	-	-	ko00000	-	-	-	MecA
KFPFDFKC_00689	622312.ROSEINA2194_00751	4.38e-136	406.0	COG0515@1|root,COG0515@2|Bacteria,1V3N4@1239|Firmicutes,25B6W@186801|Clostridia	186801|Clostridia	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
KFPFDFKC_00691	585394.RHOM_15850	1.9e-298	830.0	COG3858@1|root,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,247YF@186801|Clostridia	186801|Clostridia	M	family 18	ydhD	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Cu_amine_oxidN1,Glyco_hydro_18,SH3_3
KFPFDFKC_00692	622312.ROSEINA2194_00744	1.6e-100	299.0	COG0860@1|root,COG0860@2|Bacteria,1TQ74@1239|Firmicutes,24FT2@186801|Clostridia	186801|Clostridia	M	N-Acetylmuramoyl-L-alanine amidase	cwlD	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
KFPFDFKC_00693	622312.ROSEINA2194_00743	0.0	1046.0	28ISF@1|root,2Z8RM@2|Bacteria,1TSK2@1239|Firmicutes,249Q2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00694	585394.RHOM_15865	0.0	1207.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
KFPFDFKC_00695	585394.RHOM_15870	0.0	1020.0	COG0457@1|root,COG0464@1|root,COG0457@2|Bacteria,COG0464@2|Bacteria,1TY3C@1239|Firmicutes,248IE@186801|Clostridia	186801|Clostridia	O	Psort location Cytoplasmic, score	SpoVK	-	-	-	-	-	-	-	-	-	-	-	TPR_8
KFPFDFKC_00696	585394.RHOM_15875	4.67e-201	571.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
KFPFDFKC_00697	585394.RHOM_15890	0.0	1386.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia	186801|Clostridia	C	aconitate hydratase	ybhJ	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
KFPFDFKC_00698	585394.RHOM_15900	0.0	977.0	COG5002@1|root,COG5002@2|Bacteria,1UM03@1239|Firmicutes,24F2S@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
KFPFDFKC_00699	622312.ROSEINA2194_02189	7.98e-156	438.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia	186801|Clostridia	KT	response regulator receiver	phoP_1	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
KFPFDFKC_00701	585394.RHOM_15910	8.34e-168	479.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia	186801|Clostridia	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
KFPFDFKC_00703	585394.RHOM_15935	2.81e-73	231.0	2C331@1|root,30RPK@2|Bacteria,1V3YF@1239|Firmicutes,24IF9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00704	622312.ROSEINA2194_00858	0.0	898.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia	186801|Clostridia	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
KFPFDFKC_00705	622312.ROSEINA2194_01478	3.81e-67	233.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1,sCache_2
KFPFDFKC_00706	585394.RHOM_14940	0.0	1145.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
KFPFDFKC_00707	585394.RHOM_15950	2.75e-266	739.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia	186801|Clostridia	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
KFPFDFKC_00708	585394.RHOM_15955	1.01e-166	469.0	COG3639@1|root,COG3639@2|Bacteria,1TQ73@1239|Firmicutes,24AGQ@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	phnE_2	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
KFPFDFKC_00709	585394.RHOM_15960	7.25e-162	457.0	COG3639@1|root,COG3639@2|Bacteria,1TR1S@1239|Firmicutes,24A7G@186801|Clostridia	186801|Clostridia	P	phosphonate ABC transporter, permease protein PhnE	phnE_1	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
KFPFDFKC_00710	585394.RHOM_15965	2.4e-157	444.0	COG3638@1|root,COG3638@2|Bacteria,1TQG6@1239|Firmicutes,249GS@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
KFPFDFKC_00711	585394.RHOM_15970	1.35e-201	565.0	COG3221@1|root,COG3221@2|Bacteria,1TR0H@1239|Firmicutes,24A3Q@186801|Clostridia	186801|Clostridia	P	ABC-type phosphate phosphonate transport system periplasmic component	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
KFPFDFKC_00712	585394.RHOM_15975	1.12e-165	471.0	COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,248K0@186801|Clostridia	186801|Clostridia	K	Transcriptional	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
KFPFDFKC_00713	1226325.HMPREF1548_01833	3.6e-94	283.0	COG0496@1|root,COG0496@2|Bacteria,1TS2T@1239|Firmicutes,24BI5@186801|Clostridia,36F35@31979|Clostridiaceae	186801|Clostridia	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
KFPFDFKC_00714	1430331.EP10_03905	1.08e-75	242.0	COG0827@1|root,COG0827@2|Bacteria,1UZYA@1239|Firmicutes	1239|Firmicutes	L	BsuBI/PstI restriction endonuclease C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	BsuBI_PstI_RE
KFPFDFKC_00715	411463.EUBVEN_00713	1.07e-113	352.0	COG0827@1|root,COG0827@2|Bacteria,1UXY1@1239|Firmicutes,24B3U@186801|Clostridia,25Y8Q@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	2.1.1.72	ko:K07317	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Eco57I,N6_Mtase
KFPFDFKC_00716	585394.RHOM_00600	2.12e-90	278.0	COG2720@1|root,COG2720@2|Bacteria,1V5AV@1239|Firmicutes,24HJP@186801|Clostridia	186801|Clostridia	V	vancomycin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,CW_binding_2,VanW
KFPFDFKC_00717	585394.RHOM_15990	7.52e-232	645.0	COG1228@1|root,COG1228@2|Bacteria,1TPNQ@1239|Firmicutes,248UT@186801|Clostridia	186801|Clostridia	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
KFPFDFKC_00719	140626.JHWB01000022_gene2044	1.55e-292	810.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
KFPFDFKC_00720	140626.JHWB01000022_gene2043	3.49e-35	121.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia	186801|Clostridia	G	phosphocarrier, HPr family	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
KFPFDFKC_00721	622312.ROSEINA2194_04380	0.0	997.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia	186801|Clostridia	G	Phosphotransferase System	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
KFPFDFKC_00722	622312.ROSEINA2194_04379	9.34e-177	497.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,249RK@186801|Clostridia	186801|Clostridia	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	pfkB	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
KFPFDFKC_00723	622312.ROSEINA2194_04378	7.34e-138	394.0	COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,2498W@186801|Clostridia	186801|Clostridia	K	transcriptional regulator DeoR family	fruR	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
KFPFDFKC_00724	622312.ROSEINA2194_04377	2.31e-73	228.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24F4A@186801|Clostridia	186801|Clostridia	G	phosphoglycerate mutase	-	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
KFPFDFKC_00726	871968.DESME_09030	5.74e-24	92.0	COG3655@1|root,COG3655@2|Bacteria,1VEM0@1239|Firmicutes,24QPN@186801|Clostridia,2660R@186807|Peptococcaceae	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
KFPFDFKC_00728	1536769.P40081_27475	6.64e-12	68.6	COG2856@1|root,COG2856@2|Bacteria,1VF46@1239|Firmicutes	1239|Firmicutes	E	Pfam:DUF955	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
KFPFDFKC_00729	658088.HMPREF0987_00322	3.7e-240	662.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,27IIM@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Putative transposase DNA-binding domain	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
KFPFDFKC_00730	471875.RUMLAC_02064	1.37e-79	239.0	COG1943@1|root,COG1943@2|Bacteria,1V1CM@1239|Firmicutes,24BK2@186801|Clostridia,3WIMI@541000|Ruminococcaceae	186801|Clostridia	L	PFAM transposase IS200-family protein	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
KFPFDFKC_00731	515622.bpr_IV192	6.81e-30	134.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,4C0DJ@830|Butyrivibrio	186801|Clostridia	U	Signal peptidase, peptidase S26	lepB1	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
KFPFDFKC_00732	515622.bpr_IV193	6.64e-26	108.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
KFPFDFKC_00735	997829.HMPREF1121_00079	1.05e-11	73.6	COG1475@1|root,COG1475@2|Bacteria,4NFZ9@976|Bacteroidetes,2FP81@200643|Bacteroidia,22WNK@171551|Porphyromonadaceae	976|Bacteroidetes	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
KFPFDFKC_00736	639282.DEFDS_P212	2.99e-14	79.0	COG1192@1|root,COG1192@2|Bacteria	2|Bacteria	D	plasmid maintenance	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
KFPFDFKC_00737	1408324.JNJK01000031_gene3541	5.06e-49	174.0	28KJW@1|root,2ZA4U@2|Bacteria,1V0AC@1239|Firmicutes,24CHG@186801|Clostridia,27TVQ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	StbA
KFPFDFKC_00744	1408324.JNJK01000031_gene3534	1.56e-150	473.0	COG3451@1|root,COG3451@2|Bacteria,1TQGE@1239|Firmicutes,24ACY@186801|Clostridia,27T7T@186928|unclassified Lachnospiraceae	186801|Clostridia	U	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
KFPFDFKC_00747	1408324.JNJK01000014_gene2038	7.09e-84	293.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia,27R25@186928|unclassified Lachnospiraceae	186801|Clostridia	U	TraM recognition site of TraD and TraG	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf,TraG-D_C
KFPFDFKC_00748	1280676.AUJO01000016_gene1135	5.21e-239	660.0	COG3547@1|root,COG3547@2|Bacteria,1V427@1239|Firmicutes,24E1F@186801|Clostridia,4BYYJ@830|Butyrivibrio	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
KFPFDFKC_00749	1280671.AUJH01000004_gene3038	4.54e-68	229.0	COG5527@1|root,COG5527@2|Bacteria,1V518@1239|Firmicutes,24J29@186801|Clostridia,4BZ10@830|Butyrivibrio	186801|Clostridia	L	Initiator Replication protein	-	-	-	-	-	-	-	-	-	-	-	-	Rep_3
KFPFDFKC_00754	585394.RHOM_05225	1.9e-177	503.0	COG0630@1|root,COG0630@2|Bacteria,1UHT2@1239|Firmicutes,25EN1@186801|Clostridia	186801|Clostridia	NU	COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
KFPFDFKC_00755	585394.RHOM_05230	3.9e-124	381.0	28I5Y@1|root,2Z892@2|Bacteria,1UYUF@1239|Firmicutes,24CM9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00756	585394.RHOM_05235	4.5e-24	95.5	2EG0W@1|root,339SX@2|Bacteria,1VKDR@1239|Firmicutes,24S7Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00760	397290.C810_04881	3.73e-17	93.6	COG3942@1|root,COG5492@1|root,COG3942@2|Bacteria,COG5492@2|Bacteria,1VND5@1239|Firmicutes,24EWT@186801|Clostridia,27PB2@186928|unclassified Lachnospiraceae	186801|Clostridia	N	GBS Bsp-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,CW_binding_1,Flg_new,GBS_Bsp-like,RicinB_lectin_2,SH3_3
KFPFDFKC_00761	1410674.JNKU01000001_gene188	7.14e-202	566.0	COG0675@1|root,COG0675@2|Bacteria,1TT4J@1239|Firmicutes,4HEKB@91061|Bacilli,3F481@33958|Lactobacillaceae	91061|Bacilli	L	Probable transposase	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
KFPFDFKC_00762	397290.C810_01488	5.09e-32	117.0	2C7AV@1|root,32S15@2|Bacteria,1VE12@1239|Firmicutes,24N4J@186801|Clostridia	186801|Clostridia	S	zinc-finger-containing domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3268
KFPFDFKC_00763	515622.bpr_IV072	4.44e-22	101.0	2F4UU@1|root,33XH5@2|Bacteria,1VW76@1239|Firmicutes,250XP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00764	585394.RHOM_08580	0.0	931.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	traI	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
KFPFDFKC_00768	492774.JQMB01000001_gene5620	6.16e-10	69.7	COG3505@1|root,COG3505@2|Bacteria,1MV1G@1224|Proteobacteria,2TR6N@28211|Alphaproteobacteria,4BAUM@82115|Rhizobiaceae	28211|Alphaproteobacteria	U	Type IV secretory pathway, VirD4	virD4	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf
KFPFDFKC_00769	585394.RHOM_04340	7.19e-256	707.0	28HI8@1|root,2Z7TS@2|Bacteria,1TQTK@1239|Firmicutes,249WK@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4317
KFPFDFKC_00770	397291.C804_01124	2.75e-23	97.1	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
KFPFDFKC_00771	411470.RUMGNA_01910	4.95e-56	186.0	COG0328@1|root,COG3341@1|root,COG0328@2|Bacteria,COG3341@2|Bacteria,1V442@1239|Firmicutes,24HSE@186801|Clostridia,3Y0G9@572511|Blautia	186801|Clostridia	L	double-stranded RNA RNA-DNA hybrid binding protein	rnhA	-	3.1.26.4	ko:K03469,ko:K06993	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,RNase_H
KFPFDFKC_00774	1235793.C809_02213	3.63e-81	245.0	2EECP@1|root,30E7Y@2|Bacteria,1V4FS@1239|Firmicutes,24I0P@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00775	397290.C810_01492	2.14e-07	55.5	2B5Z1@1|root,31YV6@2|Bacteria,1UDZ2@1239|Firmicutes,25ITD@186801|Clostridia,27SPM@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00780	742740.HMPREF9474_03129	6.75e-77	229.0	COG1403@1|root,COG1403@2|Bacteria,1VKCV@1239|Firmicutes,24VRS@186801|Clostridia,221EA@1506553|Lachnoclostridium	186801|Clostridia	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
KFPFDFKC_00781	632245.CLP_1629	5.38e-44	153.0	2CWYZ@1|root,32T0P@2|Bacteria,1VYWB@1239|Firmicutes,24SU1@186801|Clostridia,36S42@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00784	397291.C804_00950	1.63e-136	398.0	COG0175@1|root,COG0175@2|Bacteria,1TSEE@1239|Firmicutes,24EZM@186801|Clostridia,27RZB@186928|unclassified Lachnospiraceae	186801|Clostridia	EH	Phosphoadenosine phosphosulfate reductase family	-	-	-	-	-	-	-	-	-	-	-	-	PAPS_reduct
KFPFDFKC_00785	1235800.C819_02255	2.54e-247	696.0	COG0270@1|root,COG0270@2|Bacteria,1TQS8@1239|Firmicutes,24DG1@186801|Clostridia,27M09@186928|unclassified Lachnospiraceae	186801|Clostridia	L	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
KFPFDFKC_00786	411468.CLOSCI_00302	6.49e-156	441.0	COG0338@1|root,COG0338@2|Bacteria,1UBIY@1239|Firmicutes,24D2Y@186801|Clostridia,223ZF@1506553|Lachnoclostridium	186801|Clostridia	L	D12 class N6 adenine-specific DNA methyltransferase	-	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
KFPFDFKC_00787	742740.HMPREF9474_03129	9.21e-77	229.0	COG1403@1|root,COG1403@2|Bacteria,1VKCV@1239|Firmicutes,24VRS@186801|Clostridia,221EA@1506553|Lachnoclostridium	186801|Clostridia	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
KFPFDFKC_00789	1235790.C805_00061	3.83e-71	217.0	2DZY9@1|root,32VN1@2|Bacteria,1VE0V@1239|Firmicutes,24P7G@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00792	411469.EUBHAL_01693	1.08e-88	260.0	COG1943@1|root,COG1943@2|Bacteria,1V5MU@1239|Firmicutes,24HFH@186801|Clostridia	186801|Clostridia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
KFPFDFKC_00793	411469.EUBHAL_01694	1.85e-263	723.0	COG0675@1|root,COG0675@2|Bacteria,1TT4J@1239|Firmicutes,24CV7@186801|Clostridia,25WYG@186806|Eubacteriaceae	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
KFPFDFKC_00794	1280698.AUJS01000061_gene1113	1.75e-99	306.0	COG3950@1|root,COG3950@2|Bacteria,1UJJK@1239|Firmicutes,24CJD@186801|Clostridia	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
KFPFDFKC_00799	1450694.BTS2_3308	1.93e-164	484.0	COG0827@1|root,COG0827@2|Bacteria,1VR0X@1239|Firmicutes	1239|Firmicutes	L	Domain of unknown function (DUF4942)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4942
KFPFDFKC_00812	411461.DORFOR_01893	7.52e-25	100.0	2ACYX@1|root,312KM@2|Bacteria,1UQ0N@1239|Firmicutes,257NB@186801|Clostridia,27X4Q@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00813	97139.C824_00149	3.45e-76	236.0	2BSK9@1|root,32MNU@2|Bacteria,1UTWW@1239|Firmicutes,254PV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00815	1090320.KB900605_gene293	7.96e-11	66.2	28MCT@1|root,2ZD18@2|Bacteria,1QTS0@1224|Proteobacteria,2U5SY@28211|Alphaproteobacteria,2K2TW@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00817	1408324.JNJK01000014_gene1984	2.81e-37	132.0	28XUQ@1|root,2ZJR3@2|Bacteria,1W60Q@1239|Firmicutes,255HC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00819	411462.DORLON_00738	1.69e-128	398.0	COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,2484I@186801|Clostridia,27V6I@189330|Dorea	186801|Clostridia	L	UvrD-like helicase C-terminal domain	yjcD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
KFPFDFKC_00820	1042156.CXIVA_13410	0.0	1051.0	COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia,36DS9@31979|Clostridiaceae	186801|Clostridia	F	Ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
KFPFDFKC_00821	658655.HMPREF0988_00556	2.94e-45	151.0	2EASV@1|root,334UU@2|Bacteria,1VEJX@1239|Firmicutes,24R23@186801|Clostridia,27P33@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00822	658655.HMPREF0988_00555	1.57e-107	328.0	COG2169@1|root,COG2169@2|Bacteria,1TR37@1239|Firmicutes,24A8S@186801|Clostridia,27IF9@186928|unclassified Lachnospiraceae	186801|Clostridia	F	DNA/RNA non-specific endonuclease	-	-	-	ko:K15051	-	-	-	-	ko00000	-	-	-	Ada_Zn_binding,Endonuclea_NS_2
KFPFDFKC_00823	1410674.JNKU01000001_gene188	5.28e-190	536.0	COG0675@1|root,COG0675@2|Bacteria,1TT4J@1239|Firmicutes,4HEKB@91061|Bacilli,3F481@33958|Lactobacillaceae	91061|Bacilli	L	Probable transposase	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
KFPFDFKC_00824	1410674.JNKU01000001_gene189	2.04e-82	244.0	COG1943@1|root,COG1943@2|Bacteria,1VAIQ@1239|Firmicutes,4HI29@91061|Bacilli,3F68H@33958|Lactobacillaceae	91061|Bacilli	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
KFPFDFKC_00831	1235802.C823_04048	1.11e-158	466.0	COG0326@1|root,COG0326@2|Bacteria,1VDCC@1239|Firmicutes,25Q1V@186801|Clostridia,25YZJ@186806|Eubacteriaceae	186801|Clostridia	O	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_3
KFPFDFKC_00835	521460.Athe_1495	6.54e-06	51.2	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,42G7Y@68295|Thermoanaerobacterales	186801|Clostridia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
KFPFDFKC_00836	886882.PPSC2_p0629	1.07e-160	484.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,4HAWN@91061|Bacilli,26QT4@186822|Paenibacillaceae	91061|Bacilli	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
KFPFDFKC_00837	1473546.CH76_07855	2.72e-32	120.0	COG1787@1|root,COG1787@2|Bacteria,1VBYF@1239|Firmicutes,4HM6M@91061|Bacilli,3IXU8@400634|Lysinibacillus	91061|Bacilli	V	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_cat
KFPFDFKC_00842	622312.ROSEINA2194_00335	7.51e-15	72.4	COG3682@1|root,COG3682@2|Bacteria,1VESD@1239|Firmicutes,24SYG@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, BlaI MecI CopY family	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
KFPFDFKC_00845	1235790.C805_03640	3.2e-135	425.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,248P4@186801|Clostridia,25Y6Q@186806|Eubacteriaceae	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
KFPFDFKC_00846	130081.XP_005708136.1	8.15e-05	52.4	COG0465@1|root,KOG0731@2759|Eukaryota	2759|Eukaryota	O	metalloendopeptidase activity	FTSH1	GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009314,GO:0009416,GO:0009507,GO:0009526,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009628,GO:0009642,GO:0009644,GO:0009719,GO:0009725,GO:0009735,GO:0009765,GO:0009892,GO:0009941,GO:0009987,GO:0010033,GO:0010109,GO:0010205,GO:0010206,GO:0010304,GO:0015979,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0019684,GO:0022607,GO:0030091,GO:0030163,GO:0031323,GO:0031324,GO:0031967,GO:0031975,GO:0031976,GO:0031977,GO:0031984,GO:0034357,GO:0034622,GO:0042221,GO:0042548,GO:0042623,GO:0042651,GO:0043155,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043467,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0048564,GO:0050789,GO:0050794,GO:0050896,GO:0055035,GO:0065003,GO:0065007,GO:0070011,GO:0071704,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1905156	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
KFPFDFKC_00851	903814.ELI_3131	3.86e-82	251.0	COG0175@1|root,COG0175@2|Bacteria,1TQBQ@1239|Firmicutes,2493M@186801|Clostridia	186801|Clostridia	EH	sulfate reduction	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00857	1410628.JNKS01000054_gene541	2.49e-190	547.0	COG0270@1|root,COG0270@2|Bacteria,1TSNX@1239|Firmicutes,2490C@186801|Clostridia,27IIV@186928|unclassified Lachnospiraceae	186801|Clostridia	H	C-5 cytosine-specific DNA methylase	haeIIIM	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
KFPFDFKC_00858	411461.DORFOR_00895	7.35e-40	149.0	28PM6@1|root,2ZCAA@2|Bacteria,1V4NT@1239|Firmicutes,24HIP@186801|Clostridia,27VG3@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00868	585394.RHOM_08870	0.0	1054.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
KFPFDFKC_00873	500632.CLONEX_02609	3.09e-98	298.0	COG2214@1|root,COG2214@2|Bacteria,1VC2A@1239|Firmicutes,24QD3@186801|Clostridia	186801|Clostridia	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00877	585394.RHOM_03700	3.56e-142	406.0	COG0561@1|root,COG0561@2|Bacteria,1V1JB@1239|Firmicutes,24AY8@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
KFPFDFKC_00878	585394.RHOM_10215	0.0	972.0	COG0369@1|root,COG1151@2|Bacteria,1TP8X@1239|Firmicutes,247IN@186801|Clostridia	186801|Clostridia	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
KFPFDFKC_00880	622312.ROSEINA2194_03062	2.72e-224	621.0	COG0371@1|root,COG0371@2|Bacteria,1TR6W@1239|Firmicutes,25CDJ@186801|Clostridia	186801|Clostridia	C	3-dehydroquinate synthase	egsA	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
KFPFDFKC_00882	1410624.JNKK01000034_gene2571	1.52e-09	62.8	COG0531@1|root,COG0642@1|root,COG0784@1|root,COG0531@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,27I78@186928|unclassified Lachnospiraceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2,HATPase_c,HisKA,Response_reg
KFPFDFKC_00884	585394.RHOM_03675	7.76e-85	253.0	2ANER@1|root,31DDD@2|Bacteria,1V46U@1239|Firmicutes,24JDI@186801|Clostridia	186801|Clostridia	S	stage V sporulation protein AC	spoVAC	-	-	ko:K06405	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
KFPFDFKC_00885	585394.RHOM_03670	1.36e-46	152.0	2EJW5@1|root,33DKW@2|Bacteria,1VPSK@1239|Firmicutes,24W6H@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF3837)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3837
KFPFDFKC_00886	585394.RHOM_03665	4.05e-55	176.0	2AF43@1|root,3152T@2|Bacteria,1VFMI@1239|Firmicutes,24RBI@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K06404	-	-	-	-	ko00000	-	-	-	SpoVAB
KFPFDFKC_00887	585394.RHOM_03660	2.19e-103	304.0	28PNE@1|root,2ZCB6@2|Bacteria,1V214@1239|Firmicutes,24DN2@186801|Clostridia	186801|Clostridia	S	COG NOG11305 non supervised orthologous group	spoVAA	-	-	ko:K06403	-	-	-	-	ko00000	-	-	-	SporV_AA
KFPFDFKC_00889	622312.ROSEINA2194_02462	3.48e-134	385.0	COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,24A25@186801|Clostridia	186801|Clostridia	K	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7,ThrE
KFPFDFKC_00890	585394.RHOM_03645	1.58e-73	223.0	COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,24R80@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ThrE_2
KFPFDFKC_00891	1410618.JNKI01000001_gene1318	1.47e-30	124.0	COG0642@1|root,COG0784@1|root,COG0834@1|root,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,4H30J@909932|Negativicutes	909932|Negativicutes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,SBP_bac_3
KFPFDFKC_00894	666681.M301_0409	3.2e-21	106.0	COG3850@1|root,COG5001@1|root,COG3850@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VKCJ@28216|Betaproteobacteria,2KKKT@206350|Nitrosomonadales	206350|Nitrosomonadales	T	Periplasmic sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,EAL,GGDEF,HAMP
KFPFDFKC_00895	585394.RHOM_03640	2.43e-291	815.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247Q9@186801|Clostridia	186801|Clostridia	S	Abc transporter	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
KFPFDFKC_00896	622312.ROSEINA2194_00341	0.0	944.0	COG4868@1|root,COG4868@2|Bacteria,1TQYE@1239|Firmicutes,247YI@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1846
KFPFDFKC_00897	411489.CLOL250_02693	1.17e-111	351.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	AMPK1_CBM,Alpha-amylase,Big_2,Big_5,CBM_48,Flg_new,Gram_pos_anchor,PUD,SLH
KFPFDFKC_00898	1121344.JHZO01000003_gene939	1.93e-59	190.0	COG1704@1|root,COG1704@2|Bacteria,1V3Z0@1239|Firmicutes,24IH4@186801|Clostridia,3WM16@541000|Ruminococcaceae	186801|Clostridia	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
KFPFDFKC_00900	1007096.BAGW01000014_gene1156	7.62e-78	254.0	COG3290@1|root,COG3290@2|Bacteria,1TS6E@1239|Firmicutes,24DDI@186801|Clostridia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
KFPFDFKC_00901	622312.ROSEINA2194_00344	3.32e-130	374.0	COG3279@1|root,COG3279@2|Bacteria,1TSDB@1239|Firmicutes,24MQ4@186801|Clostridia	186801|Clostridia	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
KFPFDFKC_00902	585394.RHOM_03635	1.34e-239	684.0	COG2200@1|root,COG2200@2|Bacteria,1TQRN@1239|Firmicutes,247QG@186801|Clostridia	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
KFPFDFKC_00903	622312.ROSEINA2194_02467	9.5e-142	402.0	COG2357@1|root,COG2357@2|Bacteria,1TSC9@1239|Firmicutes,25CET@186801|Clostridia	186801|Clostridia	S	RelA SpoT domain protein	spoT	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
KFPFDFKC_00904	537007.BLAHAN_06528	4.17e-191	537.0	COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,247P0@186801|Clostridia,3XZ5V@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K07035	-	-	-	-	ko00000	-	-	-	PTS_EIIC_2
KFPFDFKC_00905	1064535.MELS_0830	4.14e-25	106.0	292FV@1|root,2ZQ01@2|Bacteria,1V62Q@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00906	1297581.H919_06536	1.3e-127	381.0	COG1106@1|root,COG1106@2|Bacteria,1TSBY@1239|Firmicutes,4HIIN@91061|Bacilli	91061|Bacilli	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K06926	-	-	-	-	ko00000	-	-	-	AAA_21
KFPFDFKC_00907	1235798.C817_00762	9.75e-166	481.0	28K2E@1|root,2Z9RR@2|Bacteria,1TRJ6@1239|Firmicutes,24F8S@186801|Clostridia	186801|Clostridia	S	CRISPR-associated protein (Cas_Csm6)	-	-	-	-	-	-	-	-	-	-	-	-	Cas_Csm6
KFPFDFKC_00908	1235798.C817_00761	4.37e-45	148.0	COG1343@1|root,COG1343@2|Bacteria,1VFRC@1239|Firmicutes,24R2N@186801|Clostridia	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
KFPFDFKC_00909	1235798.C817_00760	2.1e-187	526.0	COG1518@1|root,COG1518@2|Bacteria,1TQWG@1239|Firmicutes,24889@186801|Clostridia	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
KFPFDFKC_00910	1235798.C817_00759	7.99e-143	417.0	COG1332@1|root,COG1332@2|Bacteria,1V8JA@1239|Firmicutes,24IAY@186801|Clostridia	186801|Clostridia	L	CRISPR-associated RAMP protein, Csm5 family	csm5	-	-	ko:K19140	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
KFPFDFKC_00911	1235798.C817_00758	2.93e-118	349.0	COG1567@1|root,COG1567@2|Bacteria,1V4UZ@1239|Firmicutes,24IT6@186801|Clostridia	186801|Clostridia	L	CRISPR-associated RAMP protein, Csm4 family	csm4	-	-	ko:K19139	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
KFPFDFKC_00912	1235798.C817_00757	6.59e-99	293.0	COG1337@1|root,COG1337@2|Bacteria,1V3DM@1239|Firmicutes,24IQD@186801|Clostridia	186801|Clostridia	L	CRISPR-associated RAMP protein, Csm3 family	csm3	-	-	ko:K09002	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
KFPFDFKC_00913	1235798.C817_00756	4.57e-47	155.0	COG1421@1|root,COG1421@2|Bacteria,1VGBY@1239|Firmicutes,24R4K@186801|Clostridia	186801|Clostridia	L	CRISPR-associated protein, Csm2 family	csm2	-	-	ko:K19138	-	-	-	-	ko00000,ko02048	-	-	-	Csm2_III-A
KFPFDFKC_00914	1235798.C817_00755	0.0	930.0	COG1353@1|root,COG1353@2|Bacteria,1TRW5@1239|Firmicutes,24BI3@186801|Clostridia	186801|Clostridia	S	CRISPR-associated protein, Csm1 family	csm1	-	-	ko:K07016	-	-	-	-	ko00000,ko02048	-	-	-	HD
KFPFDFKC_00915	1235798.C817_00754	1.94e-99	296.0	COG5551@1|root,COG5551@2|Bacteria,1V7VJ@1239|Firmicutes,24IY3@186801|Clostridia	186801|Clostridia	S	CRISPR-associated endoribonuclease Cas6	cas6	-	-	-	-	-	-	-	-	-	-	-	CRISPR_Cas6
KFPFDFKC_00916	633697.EubceDRAFT1_0116	5.32e-117	337.0	COG2184@1|root,COG2184@2|Bacteria,1TPUZ@1239|Firmicutes,248XF@186801|Clostridia,25W8Z@186806|Eubacteriaceae	186801|Clostridia	D	Fic/DOC family	fic	-	-	ko:K04095	-	-	-	-	ko00000,ko03036	-	-	-	Bro-N,Fic
KFPFDFKC_00917	622312.ROSEINA2194_02469	2.72e-51	162.0	2CGVU@1|root,32S4Q@2|Bacteria,1V9YX@1239|Firmicutes,24NX8@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00918	622312.ROSEINA2194_02470	5.02e-132	382.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
KFPFDFKC_00919	585394.RHOM_03615	2.02e-221	612.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia	186801|Clostridia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
KFPFDFKC_00920	585394.RHOM_03610	0.0	1994.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia	186801|Clostridia	L	DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
KFPFDFKC_00921	397291.C804_03982	0.0	1011.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,27K0D@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3372,PUD
KFPFDFKC_00922	1280676.AUJO01000012_gene3474	0.0	931.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,4BYXB@830|Butyrivibrio	186801|Clostridia	G	Alpha-amylase domain	malL	-	3.2.1.1,3.2.1.10	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
KFPFDFKC_00923	537007.BLAHAN_05096	1.79e-312	882.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,3XZ46@572511|Blautia	186801|Clostridia	G	Domain of unknown function (DUF5110)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4968,DUF5110,Glyco_hydro_31
KFPFDFKC_00924	1382315.JPOI01000001_gene107	1.11e-83	264.0	COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,4HBNT@91061|Bacilli,1WFIB@129337|Geobacillus	91061|Bacilli	K	helix_turn _helix lactose operon repressor	cytR	-	-	ko:K02529,ko:K03604	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
KFPFDFKC_00925	1280688.AUJB01000012_gene2575	1.21e-10	60.8	COG0637@1|root,COG0637@2|Bacteria,1UZE0@1239|Firmicutes,24DWR@186801|Clostridia,3NH8G@46205|Pseudobutyrivibrio	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	pgmB	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
KFPFDFKC_00926	1408312.JNJS01000002_gene213	1.43e-26	102.0	COG0637@1|root,COG0637@2|Bacteria,1UZE0@1239|Firmicutes,24DWR@186801|Clostridia,3NH8G@46205|Pseudobutyrivibrio	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	pgmB	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
KFPFDFKC_00927	622312.ROSEINA2194_02474	1.58e-168	474.0	COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,2485C@186801|Clostridia	186801|Clostridia	S	Phospholipase, patatin family	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
KFPFDFKC_00928	483218.BACPEC_01903	7.63e-266	734.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,2685U@186813|unclassified Clostridiales	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
KFPFDFKC_00929	622312.ROSEINA2194_02475	0.0	1422.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
KFPFDFKC_00930	1458462.JNLK01000001_gene1937	6.65e-158	456.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248IH@186801|Clostridia,27K39@186928|unclassified Lachnospiraceae	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
KFPFDFKC_00931	1458462.JNLK01000001_gene1936	0.0	1080.0	COG2206@1|root,COG3275@1|root,COG3292@1|root,COG2206@2|Bacteria,COG3275@2|Bacteria,COG3292@2|Bacteria,1UZN2@1239|Firmicutes,25EWN@186801|Clostridia	186801|Clostridia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,GAF_2,HAMP,HD,HD_5,PAS_9,Reg_prop,Response_reg,Y_Y_Y,dCache_1
KFPFDFKC_00932	411461.DORFOR_02222	5.86e-95	284.0	COG3404@1|root,COG3404@2|Bacteria,1V14R@1239|Firmicutes,24D90@186801|Clostridia,27VNB@189330|Dorea	186801|Clostridia	E	Formiminotransferase-cyclodeaminase	fchA	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
KFPFDFKC_00933	411462.DORLON_02488	1.35e-156	444.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,27VGK@189330|Dorea	186801|Clostridia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
KFPFDFKC_00934	622312.ROSEINA2194_04370	9.79e-159	463.0	COG1373@1|root,COG1373@2|Bacteria,1TQ8Z@1239|Firmicutes,2499K@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
KFPFDFKC_00935	585394.RHOM_11425	0.0	1397.0	COG1482@1|root,COG2723@1|root,COG1482@2|Bacteria,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1,PMI_typeI
KFPFDFKC_00936	585394.RHOM_11430	4.4e-174	496.0	COG2755@1|root,COG2755@2|Bacteria,1TQG2@1239|Firmicutes,24A1G@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
KFPFDFKC_00937	585394.RHOM_11435	1.01e-181	513.0	COG2755@1|root,COG2755@2|Bacteria,1TS75@1239|Firmicutes,24DPZ@186801|Clostridia	186801|Clostridia	E	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
KFPFDFKC_00938	585394.RHOM_11440	3.63e-248	681.0	COG2152@1|root,COG2152@2|Bacteria,1TQE7@1239|Firmicutes,249D0@186801|Clostridia	186801|Clostridia	G	PFAM Glycosidase	-	-	2.4.1.319,2.4.1.320	ko:K18785	-	-	R10811,R10829	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
KFPFDFKC_00939	585394.RHOM_11445	4.86e-279	763.0	COG2152@1|root,COG2152@2|Bacteria,1TNYI@1239|Firmicutes,24A1K@186801|Clostridia	186801|Clostridia	G	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose	-	-	2.4.1.281	ko:K16212	-	-	R09943	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
KFPFDFKC_00940	585394.RHOM_11450	2.88e-248	687.0	COG2942@1|root,COG2942@2|Bacteria,1TQMG@1239|Firmicutes,24C1F@186801|Clostridia	186801|Clostridia	G	Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)	-	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
KFPFDFKC_00941	1410616.JHXE01000013_gene255	8.06e-162	458.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia,3NGCJ@46205|Pseudobutyrivibrio	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
KFPFDFKC_00942	1469948.JPNB01000002_gene3876	1.64e-178	504.0	COG1175@1|root,COG1175@2|Bacteria,1TQHI@1239|Firmicutes,247ZB@186801|Clostridia,36HT0@31979|Clostridiaceae	186801|Clostridia	G	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
KFPFDFKC_00943	1280673.AUJJ01000009_gene3083	9.74e-240	672.0	COG1653@1|root,COG1653@2|Bacteria,1TS0C@1239|Firmicutes,249WW@186801|Clostridia,4BZ2U@830|Butyrivibrio	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1
KFPFDFKC_00944	585394.RHOM_11475	8.4e-151	434.0	COG1609@1|root,COG1609@2|Bacteria,1TT55@1239|Firmicutes,24A7X@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529,ko:K03604	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
KFPFDFKC_00945	1469948.JPNB01000002_gene3871	0.0	1088.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia,36EIY@31979|Clostridiaceae	186801|Clostridia	G	alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
KFPFDFKC_00946	585394.RHOM_11485	0.0	1049.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia	186801|Clostridia	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain II	-	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
KFPFDFKC_00947	1196322.A370_01851	4.62e-161	458.0	COG2730@1|root,COG2730@2|Bacteria,1TT32@1239|Firmicutes,24DD1@186801|Clostridia,36EG6@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00948	573061.Clocel_3339	2.1e-97	295.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1TQ2W@1239|Firmicutes,25BJI@186801|Clostridia	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding
KFPFDFKC_00949	622312.ROSEINA2194_02877	2.65e-85	270.0	COG1266@1|root,COG1266@2|Bacteria,1VCV8@1239|Firmicutes,24F20@186801|Clostridia	186801|Clostridia	S	CAAX amino terminal protease family protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
KFPFDFKC_00950	585394.RHOM_11490	8.34e-159	461.0	COG2843@1|root,COG2843@2|Bacteria,1UCFI@1239|Firmicutes,25CHR@186801|Clostridia	186801|Clostridia	M	Capsule synthesis protein	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
KFPFDFKC_00952	585394.RHOM_03980	4.22e-41	147.0	COG4709@1|root,COG4709@2|Bacteria,1VETQ@1239|Firmicutes,24G3G@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
KFPFDFKC_00953	622312.ROSEINA2194_02883	1.14e-59	185.0	COG1695@1|root,COG1695@2|Bacteria,1VACN@1239|Firmicutes,24MRF@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, PadR family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
KFPFDFKC_00954	585394.RHOM_03965	0.0	952.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,247KN@186801|Clostridia	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
KFPFDFKC_00955	585394.RHOM_03960	1.78e-127	378.0	COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,24C10@186801|Clostridia	186801|Clostridia	S	Secreted protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1002
KFPFDFKC_00956	585394.RHOM_03955	2.59e-180	507.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia	186801|Clostridia	I	Hydrolase, alpha beta domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
KFPFDFKC_00958	622312.ROSEINA2194_03374	0.0	876.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia	186801|Clostridia	L	Single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
KFPFDFKC_00959	622312.ROSEINA2194_03375	1.69e-113	332.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248GJ@186801|Clostridia	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA1	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
KFPFDFKC_00960	585394.RHOM_03935	2.26e-248	689.0	COG3409@1|root,COG3409@2|Bacteria,1TS29@1239|Firmicutes,247SQ@186801|Clostridia	186801|Clostridia	M	Peptidoglycan binding domain protein	sleC	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,SpoIID
KFPFDFKC_00961	622312.ROSEINA2194_03378	0.0	988.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
KFPFDFKC_00962	622312.ROSEINA2194_00443	8.94e-56	183.0	2DSNT@1|root,33GUR@2|Bacteria,1VNR5@1239|Firmicutes,24WQ3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00963	622312.ROSEINA2194_01974	2.6e-169	483.0	COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10540	ko02010,ko02030,map02010,map02030	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	Peripla_BP_4
KFPFDFKC_00964	585394.RHOM_03910	6.02e-83	261.0	COG1879@1|root,COG1879@2|Bacteria,1UD4W@1239|Firmicutes,24AYQ@186801|Clostridia	186801|Clostridia	G	COG1879 ABC-type sugar transport system periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
KFPFDFKC_00965	622312.ROSEINA2194_01972	0.0	934.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
KFPFDFKC_00966	622312.ROSEINA2194_01971	1.22e-275	766.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
KFPFDFKC_00967	585394.RHOM_03895	2.7e-38	130.0	2FJ6E@1|root,34AWI@2|Bacteria,1W149@1239|Firmicutes,254EU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00968	585394.RHOM_03890	3.55e-213	591.0	COG4211@1|root,COG4211@2|Bacteria,1UI1K@1239|Firmicutes,25EAQ@186801|Clostridia	186801|Clostridia	G	Belongs to the binding-protein-dependent transport system permease family	mglC	-	-	ko:K10541	ko02010,map02010	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	BPD_transp_2
KFPFDFKC_00969	622312.ROSEINA2194_01968	0.0	909.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia	186801|Clostridia	G	import. Responsible for energy coupling to the transport system	mglA	-	3.6.3.17	ko:K10542	ko02010,map02010	M00214	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.3	-	-	ABC_tran
KFPFDFKC_00970	585394.RHOM_03880	2e-202	568.0	COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10540	ko02010,ko02030,map02010,map02030	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	Peripla_BP_4,TAT_signal
KFPFDFKC_00971	585394.RHOM_03875	2.21e-65	201.0	COG1433@1|root,COG1433@2|Bacteria,1V7KS@1239|Firmicutes,24MUB@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
KFPFDFKC_00972	585394.RHOM_04225	1.45e-297	813.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
KFPFDFKC_00973	585394.RHOM_04220	9.79e-119	342.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia	186801|Clostridia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04225	Formyl_trans_N
KFPFDFKC_00974	585394.RHOM_04215	8.21e-225	622.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia	186801|Clostridia	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
KFPFDFKC_00975	585394.RHOM_04210	1.71e-105	305.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia	186801|Clostridia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
KFPFDFKC_00976	585394.RHOM_04205	0.0	986.0	COG2309@1|root,COG2309@2|Bacteria,1TSPE@1239|Firmicutes,24A6S@186801|Clostridia	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
KFPFDFKC_00977	585394.RHOM_04200	1.27e-114	331.0	COG1896@1|root,COG1896@2|Bacteria,1V3MK@1239|Firmicutes,24IBW@186801|Clostridia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
KFPFDFKC_00978	622312.ROSEINA2194_02252	2.53e-39	134.0	2ETB0@1|root,33KUX@2|Bacteria,1VPRN@1239|Firmicutes,24WSP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00979	585394.RHOM_04790	6.5e-279	768.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia	186801|Clostridia	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
KFPFDFKC_00980	1235790.C805_03039	5.12e-121	407.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Flg_new,LRR_5,Peptidase_M26_N,SLH,fn3
KFPFDFKC_00982	585394.RHOM_04785	9.41e-75	225.0	2AU16@1|root,31JM9@2|Bacteria,1V6CJ@1239|Firmicutes,24JBF@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00983	622312.ROSEINA2194_03436	0.0	1233.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
KFPFDFKC_00984	622312.ROSEINA2194_03438	1.71e-21	105.0	COG5184@1|root,COG5184@2|Bacteria,1VDTD@1239|Firmicutes,25FD2@186801|Clostridia	186801|Clostridia	DZ	Cadherin-like beta sandwich domain	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like
KFPFDFKC_00985	585394.RHOM_04750	1.41e-161	458.0	COG1313@1|root,COG1313@2|Bacteria,1TRUV@1239|Firmicutes,247VW@186801|Clostridia	186801|Clostridia	C	radical SAM domain protein	PflX	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
KFPFDFKC_00986	585394.RHOM_04745	7.58e-257	709.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
KFPFDFKC_00987	585394.RHOM_04740	1.93e-195	545.0	COG0657@1|root,COG0657@2|Bacteria,1UZ7B@1239|Firmicutes,25B2C@186801|Clostridia	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	3.1.1.83	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
KFPFDFKC_00988	585394.RHOM_04735	4.16e-110	322.0	2B3FQ@1|root,31W4P@2|Bacteria,1V6XF@1239|Firmicutes,24KDR@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_00989	585394.RHOM_04730	1.48e-273	753.0	COG4908@1|root,COG4908@2|Bacteria,1TQXH@1239|Firmicutes,24B2C@186801|Clostridia	186801|Clostridia	I	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	AATase
KFPFDFKC_00992	622312.ROSEINA2194_03381	5.37e-289	790.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
KFPFDFKC_00993	1235790.C805_00793	3.64e-36	124.0	COG3326@1|root,COG3326@2|Bacteria,1VEJY@1239|Firmicutes,24QJW@186801|Clostridia,25XSB@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1294
KFPFDFKC_00994	585394.RHOM_11730	0.0	1073.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,247X8@186801|Clostridia	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
KFPFDFKC_00995	585394.RHOM_11735	1.77e-314	858.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,248DD@186801|Clostridia	186801|Clostridia	C	Radical SAM	scfB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
KFPFDFKC_00996	1256908.HMPREF0373_02435	7.28e-20	80.9	2EGRK@1|root,33AHS@2|Bacteria,1VK9R@1239|Firmicutes,24UM0@186801|Clostridia,25XQV@186806|Eubacteriaceae	186801|Clostridia	S	Six-cysteine peptide SCIFF	scfA	-	-	-	-	-	-	-	-	-	-	-	SCIFF
KFPFDFKC_00997	476272.RUMHYD_00772	4.26e-267	739.0	COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia,3XYP4@572511|Blautia	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	pbuX	-	-	ko:K03458	-	-	-	-	ko00000	2.A.40	-	-	Xan_ur_permease
KFPFDFKC_00998	397290.C810_04176	7.68e-30	111.0	2E3KV@1|root,32YJ5@2|Bacteria,1VEHD@1239|Firmicutes,24RP3@186801|Clostridia,27P8F@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF3792)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3792
KFPFDFKC_00999	585394.RHOM_11750	2.74e-162	460.0	COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,24AQ8@186801|Clostridia	186801|Clostridia	G	Aldose 1-epimerase	lacX	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
KFPFDFKC_01000	1469948.JPNB01000002_gene2779	1.89e-113	330.0	COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,24CPT@186801|Clostridia,36HYG@31979|Clostridiaceae	186801|Clostridia	S	channel protein, hemolysin III family	yqfA	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
KFPFDFKC_01001	585394.RHOM_11755	0.0	889.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,2484D@186801|Clostridia	186801|Clostridia	J	Asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
KFPFDFKC_01002	585394.RHOM_11760	4.75e-148	435.0	COG0544@1|root,COG0544@2|Bacteria,1V3TB@1239|Firmicutes,24I3U@186801|Clostridia	186801|Clostridia	O	Bacterial trigger factor protein (TF) C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C,Trigger_C
KFPFDFKC_01003	585394.RHOM_05010	2.38e-45	148.0	2EK04@1|root,33DQP@2|Bacteria,1VM4D@1239|Firmicutes,24WYN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01004	585394.RHOM_05425	1.88e-138	395.0	28XBK@1|root,2ZJ9G@2|Bacteria,1V203@1239|Firmicutes,24E0K@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01005	585394.RHOM_05420	6.34e-313	852.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia	186801|Clostridia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
KFPFDFKC_01006	585394.RHOM_05415	2.56e-53	169.0	COG1687@1|root,COG1687@2|Bacteria,1V9YS@1239|Firmicutes,24MSG@186801|Clostridia	186801|Clostridia	E	branched-chain amino acid	azlD	-	-	-	-	-	-	-	-	-	-	-	AzlD
KFPFDFKC_01007	585394.RHOM_05410	2.73e-135	388.0	COG1296@1|root,COG1296@2|Bacteria,1TP8P@1239|Firmicutes,248NN@186801|Clostridia	186801|Clostridia	E	branched-chain amino acid permease (azaleucine resistance)	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
KFPFDFKC_01008	585394.RHOM_05405	5.76e-64	210.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,24JDA@186801|Clostridia	186801|Clostridia	M	transglycosylase	yjbJ	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
KFPFDFKC_01009	585394.RHOM_05400	7.13e-83	247.0	COG1846@1|root,COG1846@2|Bacteria,1V1U2@1239|Firmicutes,24FR9@186801|Clostridia	186801|Clostridia	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR
KFPFDFKC_01010	622312.ROSEINA2194_02996	8.86e-168	474.0	COG0539@1|root,COG0539@2|Bacteria,1UYC5@1239|Firmicutes,24AJ1@186801|Clostridia	186801|Clostridia	J	S1 RNA binding domain protein	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
KFPFDFKC_01011	585394.RHOM_11170	7.3e-207	610.0	COG0642@1|root,COG2205@2|Bacteria,1TP73@1239|Firmicutes,248Y6@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
KFPFDFKC_01012	585394.RHOM_11175	1.71e-148	420.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia	186801|Clostridia	KT	response regulator receiver	vanR3	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
KFPFDFKC_01013	515620.EUBELI_00411	9.54e-140	395.0	COG3340@1|root,COG3340@2|Bacteria,1V244@1239|Firmicutes,24A93@186801|Clostridia,25Y5D@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the peptidase S51 family	-	-	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
KFPFDFKC_01014	1235793.C809_01831	7.87e-34	119.0	COG4818@1|root,COG4818@2|Bacteria,1UN6A@1239|Firmicutes,25GXJ@186801|Clostridia,27Q73@186928|unclassified Lachnospiraceae	186801|Clostridia	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01015	1256908.HMPREF0373_00101	0.0	1420.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,25VB4@186806|Eubacteriaceae	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
KFPFDFKC_01016	622312.ROSEINA2194_02271	0.0	1925.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
KFPFDFKC_01017	585394.RHOM_04250	5.57e-174	492.0	COG0618@1|root,COG0618@2|Bacteria,1UKBY@1239|Firmicutes,24EAR@186801|Clostridia	186801|Clostridia	S	DHH family	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
KFPFDFKC_01018	622312.ROSEINA2194_02268	2.33e-104	306.0	COG0546@1|root,COG0546@2|Bacteria,1V4W6@1239|Firmicutes,24DB6@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
KFPFDFKC_01019	622312.ROSEINA2194_02267	3.08e-282	780.0	COG2317@1|root,COG2317@2|Bacteria,1TPS6@1239|Firmicutes,249NK@186801|Clostridia	186801|Clostridia	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
KFPFDFKC_01020	585394.RHOM_03855	1.56e-256	703.0	COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia	186801|Clostridia	E	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
KFPFDFKC_01021	585394.RHOM_03850	1.74e-49	165.0	2E0ER@1|root,32W16@2|Bacteria,1VDMK@1239|Firmicutes,24T4F@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
KFPFDFKC_01022	585394.RHOM_14785	2.59e-99	290.0	COG1853@1|root,COG1853@2|Bacteria,1V41U@1239|Firmicutes,24HTA@186801|Clostridia	186801|Clostridia	S	Conserved protein domain typically associated with flavoprotein oxygenases DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
KFPFDFKC_01023	478749.BRYFOR_07844	5.53e-76	243.0	COG5464@1|root,COG5464@2|Bacteria,1V3CA@1239|Firmicutes,24H4R@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
KFPFDFKC_01024	622312.ROSEINA2194_03392	1.53e-57	185.0	2AE00@1|root,313SJ@2|Bacteria,1V6FJ@1239|Firmicutes,24JFA@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01025	622312.ROSEINA2194_00853	1.47e-127	364.0	28NMC@1|root,2ZA4G@2|Bacteria,1UYCN@1239|Firmicutes,24ACB@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
KFPFDFKC_01026	622312.ROSEINA2194_00851	0.0	1594.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolase family 3 N-terminal domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
KFPFDFKC_01027	1235798.C817_00338	2.73e-69	227.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,27VAG@189330|Dorea	186801|Clostridia	S	Predicted AAA-ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
KFPFDFKC_01028	397288.C806_03275	7.79e-11	62.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,27IXU@186928|unclassified Lachnospiraceae	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100,1.1.1.30	ko:K00019,ko:K00059	ko00061,ko00072,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00072,map00333,map00650,map00780,map01040,map01100,map01130,map01212	M00083,M00088,M00572	R01361,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
KFPFDFKC_01029	1274374.CBLK010000019_gene2831	4.36e-116	346.0	COG0451@1|root,COG0451@2|Bacteria,1TT3X@1239|Firmicutes,4HFYX@91061|Bacilli,26SQH@186822|Paenibacillaceae	91061|Bacilli	M	3-beta hydroxysteroid dehydrogenase	galE1	-	-	-	-	-	-	-	-	-	-	-	3Beta_HSD,Epimerase
KFPFDFKC_01031	1298920.KI911353_gene1343	4.74e-86	269.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,249HQ@186801|Clostridia,21YMB@1506553|Lachnoclostridium	186801|Clostridia	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
KFPFDFKC_01032	1410626.JHXB01000002_gene643	1.51e-87	265.0	COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,248B6@186801|Clostridia,27JG7@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
KFPFDFKC_01033	658086.HMPREF0994_03731	0.0	1248.0	COG3408@1|root,COG3408@2|Bacteria,1TPY5@1239|Firmicutes,249U8@186801|Clostridia,27KIP@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
KFPFDFKC_01034	658086.HMPREF0994_03733	4.46e-131	380.0	COG1082@1|root,COG1082@2|Bacteria,1TRMY@1239|Firmicutes,24CP4@186801|Clostridia,27K31@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
KFPFDFKC_01035	478749.BRYFOR_06103	2.24e-313	868.0	COG3507@1|root,COG3507@2|Bacteria,1TQBJ@1239|Firmicutes,24CFJ@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_43
KFPFDFKC_01036	478749.BRYFOR_09770	1.13e-212	600.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
KFPFDFKC_01037	1280679.ATVX01000001_gene2951	0.0	1040.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,249UZ@186801|Clostridia,4BXZT@830|Butyrivibrio	186801|Clostridia	G	Glycosyl hydrolases family 2, sugar binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
KFPFDFKC_01038	411471.SUBVAR_04808	5.25e-226	637.0	COG2211@1|root,COG2211@2|Bacteria,1TSEH@1239|Firmicutes,24EDK@186801|Clostridia,3WNX0@541000|Ruminococcaceae	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
KFPFDFKC_01039	1506994.JNLQ01000001_gene318	3.76e-86	274.0	COG2207@1|root,COG2207@2|Bacteria,1VCDJ@1239|Firmicutes,24CSR@186801|Clostridia,4BXWP@830|Butyrivibrio	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
KFPFDFKC_01040	585394.RHOM_06075	3.87e-198	548.0	COG0235@1|root,COG0235@2|Bacteria,1TRMG@1239|Firmicutes,24BBT@186801|Clostridia	186801|Clostridia	G	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde	rhaD	-	4.1.2.19	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01785,R02263	RC00438,RC00599,RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
KFPFDFKC_01041	585394.RHOM_06070	6.88e-296	808.0	COG4806@1|root,COG4806@2|Bacteria,1TS42@1239|Firmicutes,2487G@186801|Clostridia	186801|Clostridia	G	Belongs to the rhamnose isomerase family	rhaA	-	5.3.1.14	ko:K01813	ko00051,ko01120,map00051,map01120	-	R02437	RC00434	ko00000,ko00001,ko01000	-	-	-	RhaA
KFPFDFKC_01042	585394.RHOM_06065	1.4e-263	731.0	COG1070@1|root,COG1070@2|Bacteria,1TP7Z@1239|Firmicutes,247ZU@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	rhaB	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
KFPFDFKC_01043	585394.RHOM_06060	7.47e-191	535.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1TS6T@1239|Firmicutes,247QK@186801|Clostridia	186801|Clostridia	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
KFPFDFKC_01044	1235802.C823_03873	1.24e-256	720.0	COG4262@1|root,COG4262@2|Bacteria,1UYRF@1239|Firmicutes,24AHS@186801|Clostridia,25V36@186806|Eubacteriaceae	186801|Clostridia	S	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
KFPFDFKC_01045	33035.JPJF01000009_gene1487	1.93e-285	794.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,3XZE5@572511|Blautia	186801|Clostridia	S	COG NOG08812 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
KFPFDFKC_01046	622312.ROSEINA2194_00850	1.55e-236	660.0	COG3290@1|root,COG3290@2|Bacteria,1TPZT@1239|Firmicutes,2494S@186801|Clostridia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
KFPFDFKC_01047	622312.ROSEINA2194_00849	1.06e-140	400.0	COG3279@1|root,COG3279@2|Bacteria,1UHWR@1239|Firmicutes,24G6Q@186801|Clostridia	186801|Clostridia	KT	COG3279 Response regulator of the LytR AlgR family	-	-	-	ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
KFPFDFKC_01048	622312.ROSEINA2194_04390	0.0	1413.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia	186801|Clostridia	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
KFPFDFKC_01050	796942.HMPREF9623_01507	1.93e-158	464.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1UHQC@1239|Firmicutes,25EVD@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
KFPFDFKC_01051	796942.HMPREF9623_01506	2.35e-118	343.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,248XH@186801|Clostridia	186801|Clostridia	T	response regulator receiver	mprA	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
KFPFDFKC_01054	1235800.C819_02309	3.39e-41	155.0	2BCEZ@1|root,3260K@2|Bacteria,1URZY@1239|Firmicutes,259XQ@186801|Clostridia,27QI3@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01055	622312.ROSEINA2194_00099	2.06e-38	138.0	2B7HH@1|root,320MM@2|Bacteria,1V7BY@1239|Firmicutes,24KSD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01056	411469.EUBHAL_00686	2.33e-35	120.0	2EC3Y@1|root,3362U@2|Bacteria,1VF1Z@1239|Firmicutes,24QVE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01057	411459.RUMOBE_00759	3.67e-46	148.0	2E3HI@1|root,32YG4@2|Bacteria,1VHJH@1239|Firmicutes,24V52@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01058	1256908.HMPREF0373_00535	1.15e-76	243.0	COG1522@1|root,COG2865@1|root,COG1522@2|Bacteria,COG2865@2|Bacteria,1TRTZ@1239|Firmicutes,25CHW@186801|Clostridia,25WTS@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_11,HTH_24
KFPFDFKC_01059	1280698.AUJS01000017_gene1837	1.22e-110	331.0	COG1522@1|root,COG2865@1|root,COG1522@2|Bacteria,COG2865@2|Bacteria,1TRTZ@1239|Firmicutes,25CHW@186801|Clostridia,27W54@189330|Dorea	186801|Clostridia	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_11,HTH_24
KFPFDFKC_01060	1294142.CINTURNW_3431	2.1e-313	865.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia,36DVT@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
KFPFDFKC_01061	585394.RHOM_03115	1.01e-64	199.0	COG1917@1|root,COG1917@2|Bacteria,1VCF2@1239|Firmicutes,25BAE@186801|Clostridia	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
KFPFDFKC_01062	622312.ROSEINA2194_02021	4.96e-189	535.0	COG0738@1|root,COG0738@2|Bacteria,1UZWI@1239|Firmicutes,24H3U@186801|Clostridia	186801|Clostridia	G	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
KFPFDFKC_01063	585394.RHOM_03110	4.45e-162	462.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,24BWQ@186801|Clostridia	186801|Clostridia	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
KFPFDFKC_01064	585394.RHOM_03105	1.83e-111	329.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V1DC@1239|Firmicutes,24GJV@186801|Clostridia	186801|Clostridia	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
KFPFDFKC_01065	585394.RHOM_03100	6.86e-217	615.0	COG2972@1|root,COG2972@2|Bacteria,1TSF9@1239|Firmicutes,2499Y@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase
KFPFDFKC_01066	585394.RHOM_03095	1.08e-60	191.0	2CPN3@1|root,32SJG@2|Bacteria,1VASE@1239|Firmicutes,24KG6@186801|Clostridia	186801|Clostridia	S	YcxB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
KFPFDFKC_01067	585394.RHOM_03090	3.83e-267	736.0	COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DctM
KFPFDFKC_01068	585394.RHOM_03085	1.59e-100	293.0	COG3090@1|root,COG3090@2|Bacteria,1V1US@1239|Firmicutes,24G5M@186801|Clostridia	186801|Clostridia	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
KFPFDFKC_01069	585394.RHOM_03080	5.67e-217	605.0	COG1638@1|root,COG1638@2|Bacteria,1TSSW@1239|Firmicutes,24DW9@186801|Clostridia	186801|Clostridia	G	TRAP transporter solute receptor, DctP family	-	-	-	-	-	-	-	-	-	-	-	-	DctP,TAT_signal
KFPFDFKC_01070	478749.BRYFOR_06633	1.71e-151	429.0	COG0730@1|root,COG0730@2|Bacteria,1TRFG@1239|Firmicutes,24AEX@186801|Clostridia	186801|Clostridia	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
KFPFDFKC_01071	411459.RUMOBE_02060	4.68e-63	196.0	COG1846@1|root,COG1846@2|Bacteria,1V749@1239|Firmicutes,24KYW@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
KFPFDFKC_01072	483218.BACPEC_02515	7.76e-262	733.0	COG1132@1|root,COG1132@2|Bacteria,1TPTK@1239|Firmicutes,249W7@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
KFPFDFKC_01073	515620.EUBELI_20433	1.21e-298	830.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,25URG@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
KFPFDFKC_01074	483218.BACPEC_02513	1.71e-79	239.0	COG1846@1|root,COG1846@2|Bacteria,1V8Z3@1239|Firmicutes,24I7U@186801|Clostridia,26BAN@186813|unclassified Clostridiales	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
KFPFDFKC_01075	1392493.JIAB01000001_gene729	9.67e-308	841.0	COG1350@1|root,COG1350@2|Bacteria,1UI01@1239|Firmicutes,25E8Q@186801|Clostridia,27J2Z@186928|unclassified Lachnospiraceae	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
KFPFDFKC_01076	397291.C804_04903	1e-215	673.0	COG0419@1|root,COG1121@1|root,COG0419@2|Bacteria,COG1121@2|Bacteria,1TPCS@1239|Firmicutes,24A22@186801|Clostridia,27JHC@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Putative exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
KFPFDFKC_01077	1235802.C823_05147	2.45e-180	513.0	COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,248VE@186801|Clostridia,25VTM@186806|Eubacteriaceae	186801|Clostridia	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
KFPFDFKC_01078	445972.ANACOL_01323	2.22e-43	156.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,3WHT6@541000|Ruminococcaceae	186801|Clostridia	P	E1-E2 ATPase	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
KFPFDFKC_01079	1408306.JHXX01000001_gene2019	2.11e-153	447.0	COG2312@1|root,COG2312@2|Bacteria,1V2ED@1239|Firmicutes,24BHP@186801|Clostridia,4BXEN@830|Butyrivibrio	186801|Clostridia	S	Erythromycin esterase	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Erythro_esteras
KFPFDFKC_01080	1321784.HMPREF1987_01012	7.57e-106	314.0	COG0716@1|root,COG1143@1|root,COG0716@2|Bacteria,COG1143@2|Bacteria,1TRYM@1239|Firmicutes,247NM@186801|Clostridia,25SY8@186804|Peptostreptococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Flavodoxin_3,Flavodoxin_5
KFPFDFKC_01081	397288.C806_03259	1.03e-26	101.0	COG3976@1|root,COG3976@2|Bacteria,1VFG0@1239|Firmicutes,24RHT@186801|Clostridia,27MHD@186928|unclassified Lachnospiraceae	186801|Clostridia	C	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
KFPFDFKC_01082	397288.C806_03259	1.57e-13	67.0	COG3976@1|root,COG3976@2|Bacteria,1VFG0@1239|Firmicutes,24RHT@186801|Clostridia,27MHD@186928|unclassified Lachnospiraceae	186801|Clostridia	C	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
KFPFDFKC_01083	397290.C810_01190	8.87e-114	330.0	COG1309@1|root,COG1309@2|Bacteria,1V8TI@1239|Firmicutes,24F39@186801|Clostridia,27KFG@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
KFPFDFKC_01084	622312.ROSEINA2194_02805	0.0	1633.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia	186801|Clostridia	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
KFPFDFKC_01085	908340.HMPREF9406_3409	7.17e-37	158.0	COG4886@1|root,COG5492@1|root,COG4886@2|Bacteria,COG5492@2|Bacteria,1VUQN@1239|Firmicutes,24CDA@186801|Clostridia,36JWJ@31979|Clostridiaceae	186801|Clostridia	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,Flg_new,Peptidase_C1
KFPFDFKC_01086	585394.RHOM_03735	2.29e-293	800.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia	186801|Clostridia	C	alcohol dehydrogenase	adh	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
KFPFDFKC_01087	585394.RHOM_06140	8.01e-306	874.0	28J8A@1|root,2Z93H@2|Bacteria,1UYEZ@1239|Firmicutes,24AV4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01088	411469.EUBHAL_02516	4.24e-178	504.0	COG0438@1|root,COG0438@2|Bacteria,1TPG9@1239|Firmicutes,24EAP@186801|Clostridia,25WEJ@186806|Eubacteriaceae	186801|Clostridia	M	Stealth protein CR2, conserved region 2	-	-	-	-	-	-	-	-	-	-	-	-	Stealth_CR1,Stealth_CR2,Stealth_CR3,Stealth_CR4
KFPFDFKC_01089	585394.RHOM_06135	0.0	1197.0	COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,247ND@186801|Clostridia	186801|Clostridia	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
KFPFDFKC_01090	1235792.C808_00459	7.87e-202	568.0	COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,248DW@186801|Clostridia,27IBJ@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	ko:K19955	-	-	-	-	ko00000,ko01000	-	-	-	Fe-ADH
KFPFDFKC_01091	585394.RHOM_04685	4.39e-212	597.0	COG0486@1|root,COG0486@2|Bacteria,1TQA8@1239|Firmicutes,247M4@186801|Clostridia	186801|Clostridia	S	Hydrogenase maturation GTPase HydF	hydF	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
KFPFDFKC_01092	585394.RHOM_04680	0.0	892.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia	186801|Clostridia	C	biosynthesis protein ThiH	hydG	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
KFPFDFKC_01093	585394.RHOM_04675	2.78e-193	544.0	COG0502@1|root,COG0502@2|Bacteria,1TPYQ@1239|Firmicutes,248H8@186801|Clostridia	186801|Clostridia	C	Iron-only hydrogenase maturation rSAM protein HydE	hydE	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
KFPFDFKC_01094	585394.RHOM_04670	5.81e-42	138.0	COG0864@1|root,COG0864@2|Bacteria,1VF9M@1239|Firmicutes,24QVJ@186801|Clostridia	186801|Clostridia	K	Iron-only hydrogenase system regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01095	515622.bpr_I1351	3.56e-52	167.0	COG0375@1|root,COG0375@2|Bacteria,1VABW@1239|Firmicutes,24NES@186801|Clostridia,4BZG4@830|Butyrivibrio	186801|Clostridia	S	Hydrogenase/urease nickel incorporation, metallochaperone, hypA	-	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
KFPFDFKC_01096	665956.HMPREF1032_02341	0.0	1460.0	COG0493@1|root,COG1143@1|root,COG4231@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,COG4231@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3WHYH@541000|Ruminococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_20,Fer4_9,Pyr_redox_2,Pyr_redox_3
KFPFDFKC_01097	515622.bpr_I1350	1.13e-127	366.0	COG0378@1|root,COG0378@2|Bacteria,1TS00@1239|Firmicutes,248T1@186801|Clostridia,4BXWJ@830|Butyrivibrio	186801|Clostridia	KO	CobW/HypB/UreG, nucleotide-binding domain	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
KFPFDFKC_01099	641112.ACOK01000114_gene2305	5.36e-80	240.0	COG5113@1|root,COG3236@2|Bacteria,1UY8T@1239|Firmicutes,2486K@186801|Clostridia,3WGS9@541000|Ruminococcaceae	186801|Clostridia	O	Domain of unknown function (DUF1768)	-	-	-	ko:K09935	-	-	-	-	ko00000	-	-	-	DUF1768
KFPFDFKC_01100	518637.EUBIFOR_02026	3.97e-77	231.0	29AZ1@1|root,2ZXY1@2|Bacteria,1V4KY@1239|Firmicutes,3VTCC@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01101	585501.HMPREF6123_1167	6.94e-118	341.0	28KQ0@1|root,2ZA7Z@2|Bacteria,1V4X7@1239|Firmicutes,24E87@186801|Clostridia,2PTNA@265975|Oribacterium	186801|Clostridia	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990
KFPFDFKC_01103	411489.CLOL250_02048	1.52e-18	100.0	COG3209@1|root,COG3210@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,1W1CQ@1239|Firmicutes,24Q72@186801|Clostridia,36NF6@31979|Clostridiaceae	186801|Clostridia	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01104	585394.RHOM_04645	1.09e-213	610.0	COG0726@1|root,COG0860@1|root,COG0726@2|Bacteria,COG0860@2|Bacteria,1TT1X@1239|Firmicutes,249PF@186801|Clostridia	186801|Clostridia	G	delta-lactam-biosynthetic de-N-acetylase	pdaA	-	-	ko:K01567	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
KFPFDFKC_01105	585394.RHOM_04640	2.6e-217	608.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
KFPFDFKC_01106	585394.RHOM_04635	0.0	1140.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
KFPFDFKC_01107	642492.Clole_2676	0.0	1194.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,248WR@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF5110,Glyco_hydro_31
KFPFDFKC_01108	642492.Clole_2677	7.17e-313	880.0	COG4447@1|root,COG4447@2|Bacteria,1VJ96@1239|Firmicutes	1239|Firmicutes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01109	411462.DORLON_00274	4.26e-187	531.0	COG0037@1|root,COG0607@1|root,COG0037@2|Bacteria,COG0607@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia,27VSU@189330|Dorea	186801|Clostridia	H	ATPase of the PP-loop superfamily implicated in cell cycle control	ttcA	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3,Rhodanese
KFPFDFKC_01110	622312.ROSEINA2194_04128	2.66e-308	846.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
KFPFDFKC_01111	585394.RHOM_11105	5.42e-192	534.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
KFPFDFKC_01112	585394.RHOM_11110	3.46e-271	744.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,25E6I@186801|Clostridia	186801|Clostridia	E	PFAM Cys Met metabolism	mccB	-	2.5.1.48,4.4.1.8	ko:K01739,ko:K01760	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
KFPFDFKC_01113	585394.RHOM_11115	2.25e-146	418.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UZ8Y@1239|Firmicutes,248SM@186801|Clostridia	186801|Clostridia	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
KFPFDFKC_01114	585394.RHOM_11120	0.0	895.0	COG1227@1|root,COG4109@1|root,COG1227@2|Bacteria,COG4109@2|Bacteria,1TPH6@1239|Firmicutes,248RQ@186801|Clostridia	186801|Clostridia	C	domain protein	ppaC	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
KFPFDFKC_01115	585394.RHOM_11125	8.87e-44	158.0	2E4NI@1|root,32ZHC@2|Bacteria,1VGQR@1239|Firmicutes,24RYT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01116	622312.ROSEINA2194_04139	0.0	887.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia	186801|Clostridia	G	pts system	nagE	-	2.7.1.193	ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	M00267	R05199	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7	-	-	PTS_EIIB,PTS_EIIC
KFPFDFKC_01117	622312.ROSEINA2194_04140	2.23e-89	264.0	COG2190@1|root,COG2190@2|Bacteria,1VAEB@1239|Firmicutes	1239|Firmicutes	G	PTS system, glucose subfamily, IIA	ptbA	-	-	ko:K02755,ko:K02756,ko:K02757,ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	M00265,M00266,M00268,M00270,M00271,M00272,M00303,M00806	R02738,R02780,R04111,R04394,R05132,R08559	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1,4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
KFPFDFKC_01118	622312.ROSEINA2194_04141	2.11e-86	260.0	COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,24931@186801|Clostridia	186801|Clostridia	K	transcriptional antiterminator	licT	-	-	ko:K03488	-	-	-	-	ko00000,ko03000	-	-	-	CAT_RBD,PRD
KFPFDFKC_01119	515620.EUBELI_20171	3.18e-15	75.1	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,248QD@186801|Clostridia,25W4Z@186806|Eubacteriaceae	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K11050	ko02010,map02010	M00254,M00298	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.130	-	-	ABC_tran,DUF4162
KFPFDFKC_01120	457412.RSAG_00897	7.66e-147	421.0	COG0842@1|root,COG0842@2|Bacteria,1TSH0@1239|Firmicutes,24BEN@186801|Clostridia,3WM6R@541000|Ruminococcaceae	186801|Clostridia	V	ABC-2 type transporter	-	-	-	ko:K01992,ko:K11051	ko02010,map02010	M00254,M00298	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.130	-	-	ABC2_membrane,ABC2_membrane_3
KFPFDFKC_01121	1211819.CALK01000010_gene2880	1.63e-60	195.0	COG1309@1|root,COG1309@2|Bacteria,1V3XC@1239|Firmicutes	1239|Firmicutes	K	Transcriptional regulator TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
KFPFDFKC_01122	585394.RHOM_04065	3e-189	526.0	COG2267@1|root,COG2267@2|Bacteria,1TR25@1239|Firmicutes,24APA@186801|Clostridia	186801|Clostridia	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
KFPFDFKC_01123	526218.Sterm_0486	1.26e-07	51.6	COG0693@1|root,COG0693@2|Bacteria,378YZ@32066|Fusobacteria	32066|Fusobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
KFPFDFKC_01125	515620.EUBELI_20549	0.0	949.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,25UVM@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
KFPFDFKC_01126	515620.EUBELI_20548	0.0	1056.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,25UTB@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
KFPFDFKC_01127	515620.EUBELI_20547	2.25e-62	195.0	COG1846@1|root,COG1846@2|Bacteria,1VGNE@1239|Firmicutes,25MX1@186801|Clostridia,25Z6W@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01128	622312.ROSEINA2194_00266	1.01e-39	132.0	2E7R6@1|root,3326H@2|Bacteria,1VGKC@1239|Firmicutes,24QSS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01129	1235802.C823_03868	1.8e-154	479.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,25UR7@186806|Eubacteriaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_7TM,Hpt,MASE3,PocR,Response_reg
KFPFDFKC_01130	397291.C804_05622	1.58e-60	198.0	COG0745@1|root,COG0745@2|Bacteria,1V566@1239|Firmicutes,25EMQ@186801|Clostridia,27TZD@186928|unclassified Lachnospiraceae	186801|Clostridia	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
KFPFDFKC_01131	585394.RHOM_14180	0.0	1030.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,2480C@186801|Clostridia	186801|Clostridia	M	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
KFPFDFKC_01132	585394.RHOM_14175	3.02e-232	640.0	COG1453@1|root,COG1453@2|Bacteria,1TSTA@1239|Firmicutes,249IP@186801|Clostridia	186801|Clostridia	C	aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
KFPFDFKC_01133	622312.ROSEINA2194_04026	3.79e-104	306.0	COG0546@1|root,COG0546@2|Bacteria,1V3YI@1239|Firmicutes,24CRF@186801|Clostridia	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
KFPFDFKC_01135	411459.RUMOBE_02462	2.05e-147	420.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,3Y0BE@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	ATP_bind_3,NAD_synthase,QueC
KFPFDFKC_01136	411462.DORLON_01513	3.02e-155	439.0	COG1179@1|root,COG1179@2|Bacteria,1TQ7A@1239|Firmicutes,248RA@186801|Clostridia,27VIT@189330|Dorea	186801|Clostridia	H	COG COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and THIamine biosynthesis family 1	thiF	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
KFPFDFKC_01137	1235793.C809_00892	0.0	936.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia,27JM8@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
KFPFDFKC_01138	1235793.C809_00893	2.47e-188	527.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,27KXN@186928|unclassified Lachnospiraceae	186801|Clostridia	EP	Binding-protein-dependent transport system inner membrane component	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
KFPFDFKC_01139	1235793.C809_00894	8.03e-217	602.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,27II5@186928|unclassified Lachnospiraceae	186801|Clostridia	EP	N-terminal TM domain of oligopeptide transport permease C	oppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
KFPFDFKC_01140	1235793.C809_00895	3.94e-234	647.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,27JHK@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
KFPFDFKC_01141	748224.HMPREF9436_00019	4.52e-193	539.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WN2S@541000|Ruminococcaceae	186801|Clostridia	P	Oligopeptide/dipeptide transporter, C-terminal region	oppF	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
KFPFDFKC_01142	511680.BUTYVIB_00626	1.8e-149	449.0	COG0840@1|root,COG5000@1|root,COG0840@2|Bacteria,COG5000@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,4BX8J@830|Butyrivibrio	186801|Clostridia	NT	Methyl-accepting chemotaxis protein signaling domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
KFPFDFKC_01143	742765.HMPREF9457_02253	1.04e-281	776.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,27WEJ@189330|Dorea	186801|Clostridia	E	Sodium:alanine symporter family	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
KFPFDFKC_01144	622312.ROSEINA2194_00442	2.67e-281	774.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia	186801|Clostridia	S	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
KFPFDFKC_01145	1458462.JNLK01000001_gene4	1.29e-80	246.0	28HI8@1|root,2Z9QV@2|Bacteria,1UZZ2@1239|Firmicutes,24IH2@186801|Clostridia,27MEA@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4317
KFPFDFKC_01147	515620.EUBELI_20098	1.11e-187	533.0	COG2206@1|root,COG2206@2|Bacteria,1TS2E@1239|Firmicutes,249S8@186801|Clostridia,25WUW@186806|Eubacteriaceae	186801|Clostridia	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
KFPFDFKC_01148	1469948.JPNB01000001_gene1087	7.25e-42	149.0	COG0738@1|root,COG0738@2|Bacteria,1TQPE@1239|Firmicutes,24AF8@186801|Clostridia,36F1D@31979|Clostridiaceae	186801|Clostridia	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
KFPFDFKC_01150	411467.BACCAP_01273	1.33e-40	137.0	COG1917@1|root,COG1917@2|Bacteria,1V6IB@1239|Firmicutes,24JTU@186801|Clostridia,26BXU@186813|unclassified Clostridiales	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
KFPFDFKC_01151	585394.RHOM_14165	6.4e-164	487.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,sCache_2,sCache_3_3
KFPFDFKC_01153	622312.ROSEINA2194_01846	1.29e-279	778.0	COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia	186801|Clostridia	H	cobalt chelatase	cbiK	-	4.99.1.3	ko:K02190	ko00860,ko01100,map00860,map01100	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiK
KFPFDFKC_01154	1256908.HMPREF0373_02031	8.01e-258	721.0	COG0614@1|root,COG0614@2|Bacteria,1TQ4U@1239|Firmicutes,249I2@186801|Clostridia,25UTP@186806|Eubacteriaceae	186801|Clostridia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
KFPFDFKC_01155	1256908.HMPREF0373_02030	2.89e-180	508.0	COG0609@1|root,COG0609@2|Bacteria,1TQXW@1239|Firmicutes,249TJ@186801|Clostridia,25VB9@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	btuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
KFPFDFKC_01156	1256908.HMPREF0373_02029	7.71e-185	524.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,25VKN@186806|Eubacteriaceae	186801|Clostridia	HP	K02013 iron complex transport system ATP-binding protein	fepC	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran,zf-like
KFPFDFKC_01157	592026.GCWU0000282_002961	0.0	1342.0	COG1112@1|root,COG1112@2|Bacteria,1TP20@1239|Firmicutes,24BMH@186801|Clostridia	186801|Clostridia	L	COG1112 Superfamily I DNA and RNA	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF2726
KFPFDFKC_01158	478749.BRYFOR_06207	1.32e-104	310.0	COG2186@1|root,COG2186@2|Bacteria,1V5UA@1239|Firmicutes,24BCM@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
KFPFDFKC_01159	478749.BRYFOR_06209	7.92e-255	707.0	COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,248PQ@186801|Clostridia	186801|Clostridia	EG	Gluconate	-	-	-	ko:K03299,ko:K06155,ko:K06156,ko:K06157	-	-	-	-	ko00000,ko02000	2.A.8,2.A.8.1.2,2.A.8.1.4,2.A.8.1.8	-	iHN637.CLJU_RS05690,iHN637.CLJU_RS13905	GntP_permease
KFPFDFKC_01160	457421.CBFG_01718	0.0	1025.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia	186801|Clostridia	EG	Belongs to the IlvD Edd family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
KFPFDFKC_01161	1121871.AUAT01000005_gene1736	5.02e-16	85.9	COG2971@1|root,COG2971@2|Bacteria,1V47Z@1239|Firmicutes,4IR14@91061|Bacilli	91061|Bacilli	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
KFPFDFKC_01162	140626.JHWB01000009_gene1454	4.79e-117	341.0	COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,248HK@186801|Clostridia	186801|Clostridia	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
KFPFDFKC_01163	1280664.AUIX01000021_gene2964	3.78e-170	487.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,2481N@186801|Clostridia,4BX6M@830|Butyrivibrio	186801|Clostridia	G	Amidohydrolase family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
KFPFDFKC_01164	585394.RHOM_14935	0.0	972.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia	186801|Clostridia	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
KFPFDFKC_01165	585394.RHOM_14920	4.22e-227	628.0	COG0275@1|root,COG0275@2|Bacteria,1TP5R@1239|Firmicutes,248PH@186801|Clostridia	186801|Clostridia	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH2	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
KFPFDFKC_01166	411489.CLOL250_02329	2.77e-170	481.0	COG0214@1|root,COG0214@2|Bacteria,1TPSZ@1239|Firmicutes,248C1@186801|Clostridia,36DZ4@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
KFPFDFKC_01167	411489.CLOL250_02328	4.01e-76	233.0	COG0311@1|root,COG0311@2|Bacteria,1V3I6@1239|Firmicutes,24HRT@186801|Clostridia,36I0R@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS19495	SNO
KFPFDFKC_01168	742740.HMPREF9474_02025	6.46e-142	420.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,22083@1506553|Lachnoclostridium	186801|Clostridia	V	MatE	effD	-	-	-	-	-	-	-	-	-	-	-	MatE
KFPFDFKC_01169	483218.BACPEC_03086	1.55e-61	194.0	2BIDU@1|root,32CK4@2|Bacteria,1VDRI@1239|Firmicutes,24NJ9@186801|Clostridia,26BYT@186813|unclassified Clostridiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01170	622312.ROSEINA2194_00274	1.11e-179	506.0	COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,24B0E@186801|Clostridia	186801|Clostridia	M	Linear amide C-N hydrolase, choloylglycine hydrolase family protein	cbh	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
KFPFDFKC_01171	411474.COPEUT_02079	2.24e-115	341.0	COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,24B1W@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
KFPFDFKC_01172	585394.RHOM_02250	7.53e-119	344.0	COG2364@1|root,COG2364@2|Bacteria,1US08@1239|Firmicutes,24DPK@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01173	1235793.C809_01339	2e-37	129.0	COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,24JAB@186801|Clostridia,27NWQ@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
KFPFDFKC_01174	642492.Clole_0471	9.81e-245	699.0	COG2234@1|root,COG2234@2|Bacteria,1TRWH@1239|Firmicutes,24BM1@186801|Clostridia	186801|Clostridia	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
KFPFDFKC_01175	1121115.AXVN01000103_gene864	2.37e-100	296.0	COG0454@1|root,COG0456@2|Bacteria,1V1I9@1239|Firmicutes,24GXQ@186801|Clostridia	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
KFPFDFKC_01176	622312.ROSEINA2194_00835	1.74e-30	110.0	COG2747@1|root,COG2747@2|Bacteria,1VFH9@1239|Firmicutes,24QZ8@186801|Clostridia	186801|Clostridia	KNU	Anti-sigma-28 factor, FlgM	flgM	-	-	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgM
KFPFDFKC_01177	585394.RHOM_00615	1.59e-58	187.0	2APQ2@1|root,31ETS@2|Bacteria,1V6HK@1239|Firmicutes,24KPZ@186801|Clostridia	186801|Clostridia	S	FlgN protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgN
KFPFDFKC_01178	585394.RHOM_00620	9.08e-302	838.0	COG1256@1|root,COG1256@2|Bacteria,1TPXH@1239|Firmicutes,249PE@186801|Clostridia	186801|Clostridia	N	TIGRFAM Flagellar hook-associated protein, FlgK	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
KFPFDFKC_01179	585394.RHOM_00625	1.09e-280	786.0	COG1256@1|root,COG1256@2|Bacteria,1TPXH@1239|Firmicutes,249PE@186801|Clostridia	186801|Clostridia	N	TIGRFAM Flagellar hook-associated protein, FlgK	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
KFPFDFKC_01180	585394.RHOM_00630	4.48e-234	660.0	COG1344@1|root,COG1344@2|Bacteria,1TPDT@1239|Firmicutes,248FN@186801|Clostridia	186801|Clostridia	N	Belongs to the bacterial flagellin family	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
KFPFDFKC_01181	585394.RHOM_00635	7.21e-78	234.0	COG1699@1|root,COG1699@2|Bacteria,1VA6Y@1239|Firmicutes,24QXE@186801|Clostridia	186801|Clostridia	S	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum	fliW	-	-	ko:K13626	-	-	-	-	ko00000,ko02035	-	-	-	FliW
KFPFDFKC_01182	585394.RHOM_00640	1.92e-35	121.0	COG1551@1|root,COG1551@2|Bacteria,1VEEF@1239|Firmicutes,24QPD@186801|Clostridia	186801|Clostridia	T	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
KFPFDFKC_01183	622312.ROSEINA2194_00379	7e-36	128.0	COG1334@1|root,COG1334@2|Bacteria,1VFRY@1239|Firmicutes,24QPX@186801|Clostridia	186801|Clostridia	N	PFAM Flagellar protein FlaG protein	flaG	-	-	ko:K06603	-	-	-	-	ko00000,ko02035	-	-	-	FlaG
KFPFDFKC_01184	585394.RHOM_00650	0.0	1093.0	COG1345@1|root,COG1345@2|Bacteria,1TQ66@1239|Firmicutes,248Q9@186801|Clostridia	186801|Clostridia	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
KFPFDFKC_01185	622312.ROSEINA2194_04178	4.71e-284	780.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia	186801|Clostridia	L	Reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
KFPFDFKC_01186	622312.ROSEINA2194_04142	1.56e-46	150.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
KFPFDFKC_01187	622312.ROSEINA2194_04143	0.0	911.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
KFPFDFKC_01188	622312.ROSEINA2194_04145	0.0	2296.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia	186801|Clostridia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
KFPFDFKC_01189	585394.RHOM_04830	0.0	1101.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,SBP_bac_3
KFPFDFKC_01190	585394.RHOM_04825	0.0	1025.0	COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,248ST@186801|Clostridia	186801|Clostridia	S	ABC transporter	ykpA	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
KFPFDFKC_01191	1449050.JNLE01000003_gene106	5.64e-12	73.6	2EG3M@1|root,339VN@2|Bacteria,1VN0Z@1239|Firmicutes,24UD6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01192	500632.CLONEX_03904	2.02e-84	256.0	COG0546@1|root,COG0546@2|Bacteria,1V1FQ@1239|Firmicutes,24G1U@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	nt5e	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
KFPFDFKC_01193	622312.ROSEINA2194_04469	5.1e-201	566.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
KFPFDFKC_01194	585394.RHOM_05120	1.66e-190	544.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia	186801|Clostridia	S	Stage V sporulation protein B	spoVB	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
KFPFDFKC_01195	483218.BACPEC_02966	1.55e-111	333.0	COG0484@1|root,COG0484@2|Bacteria,1TS44@1239|Firmicutes,24A9N@186801|Clostridia,26A1M@186813|unclassified Clostridiales	186801|Clostridia	O	DnaJ molecular chaperone homology domain	CbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
KFPFDFKC_01196	1160721.RBI_I01639	5.82e-75	234.0	COG0726@1|root,COG0726@2|Bacteria,1V8XF@1239|Firmicutes,24JZT@186801|Clostridia,3WIMA@541000|Ruminococcaceae	186801|Clostridia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1,Polysacc_deac_1
KFPFDFKC_01197	411474.COPEUT_00455	0.0	1248.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
KFPFDFKC_01198	515620.EUBELI_01734	4.4e-230	644.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,25V84@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
KFPFDFKC_01199	397291.C804_05617	5.09e-94	278.0	COG1443@1|root,COG1443@2|Bacteria,1V41D@1239|Firmicutes,24KU4@186801|Clostridia,27M9G@186928|unclassified Lachnospiraceae	186801|Clostridia	I	NUDIX domain	idi	-	-	-	-	-	-	-	-	-	-	-	NUDIX
KFPFDFKC_01201	622312.ROSEINA2194_03305	0.0	911.0	COG1961@1|root,COG1961@2|Bacteria,1TSXI@1239|Firmicutes,248RE@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
KFPFDFKC_01202	1235800.C819_00786	4.87e-242	684.0	COG1961@1|root,COG1961@2|Bacteria,1TQ8Y@1239|Firmicutes,247WD@186801|Clostridia,27T7X@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
KFPFDFKC_01203	622312.ROSEINA2194_01655	0.0	899.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
KFPFDFKC_01204	411459.RUMOBE_01807	1.59e-204	571.0	COG3935@1|root,COG3935@2|Bacteria,1TPPF@1239|Firmicutes,249NG@186801|Clostridia,3XYVR@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	RepA_N
KFPFDFKC_01205	411459.RUMOBE_01806	1.33e-51	162.0	2CDC9@1|root,32RXG@2|Bacteria,1VA39@1239|Firmicutes,24MYY@186801|Clostridia,3Y0N4@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF5348
KFPFDFKC_01206	411483.FAEPRAA2165_00052	9.28e-97	283.0	28I1B@1|root,2Z93C@2|Bacteria,1UJW4@1239|Firmicutes,25FBU@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3801
KFPFDFKC_01207	411483.FAEPRAA2165_00053	0.0	1166.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia,3WH6W@541000|Ruminococcaceae	186801|Clostridia	U	Type IV secretory pathway, VirD4 components	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf,TraG-D_C
KFPFDFKC_01208	411483.FAEPRAA2165_00054	1.09e-38	129.0	2BX2G@1|root,32UZ6@2|Bacteria,1VBQA@1239|Firmicutes,24NG8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01209	411483.FAEPRAA2165_00055	4.22e-41	135.0	2CDEH@1|root,32RXK@2|Bacteria,1VA17@1239|Firmicutes,24MPR@186801|Clostridia,3WJZH@541000|Ruminococcaceae	186801|Clostridia	S	Maff2 family	-	-	-	-	-	-	-	-	-	-	-	-	Maff2
KFPFDFKC_01210	411483.FAEPRAA2165_00056	5.44e-197	547.0	28HUM@1|root,2Z81B@2|Bacteria,1TNZ2@1239|Firmicutes,248SU@186801|Clostridia,3WHM9@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01211	411483.FAEPRAA2165_00057	3.59e-88	259.0	COG3451@1|root,COG3451@2|Bacteria,1V74G@1239|Firmicutes,24GFI@186801|Clostridia,3WSPP@541000|Ruminococcaceae	186801|Clostridia	U	PrgI family protein	-	-	-	-	-	-	-	-	-	-	-	-	PrgI
KFPFDFKC_01212	411483.FAEPRAA2165_00058	0.0	1555.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,248ND@186801|Clostridia,3WG7K@541000|Ruminococcaceae	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
KFPFDFKC_01213	411468.CLOSCI_00100	1.17e-218	602.0	COG0863@1|root,COG0863@2|Bacteria,1TR56@1239|Firmicutes,248NR@186801|Clostridia	186801|Clostridia	L	Belongs to the N(4) N(6)-methyltransferase family	cfr9IM	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
KFPFDFKC_01214	411483.FAEPRAA2165_00060	0.0	1261.0	COG0791@1|root,COG0791@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia,3WGA2@541000|Ruminococcaceae	186801|Clostridia	M	NlpC p60 family protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAP
KFPFDFKC_01215	411468.CLOSCI_00098	6.05e-45	146.0	2AF03@1|root,32VGP@2|Bacteria,1VDWA@1239|Firmicutes,24KAG@186801|Clostridia,220TX@1506553|Lachnoclostridium	186801|Clostridia	S	Domain of unknown function (DUF4315)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4315
KFPFDFKC_01216	411483.FAEPRAA2165_00062	4.34e-132	378.0	28HUZ@1|root,2Z81G@2|Bacteria,1TS04@1239|Firmicutes,24AUT@186801|Clostridia,3WHA3@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4366)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4366
KFPFDFKC_01217	622312.ROSEINA2194_01309	0.0	1266.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	-	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
KFPFDFKC_01218	411468.CLOSCI_00095	0.0	2459.0	COG1669@1|root,COG4227@1|root,COG4734@1|root,COG1669@2|Bacteria,COG4227@2|Bacteria,COG4734@2|Bacteria,1TQN4@1239|Firmicutes,2482H@186801|Clostridia,21ZD6@1506553|Lachnoclostridium	186801|Clostridia	L	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA,DUF4316,Peptidase_M78,YodL
KFPFDFKC_01219	411483.FAEPRAA2165_00075	7.21e-167	473.0	COG0249@1|root,COG0249@2|Bacteria,1UYR7@1239|Firmicutes,248ZW@186801|Clostridia,3WH7E@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01220	411483.FAEPRAA2165_00076	1.37e-36	124.0	2DN7M@1|root,32VZW@2|Bacteria,1V9Y5@1239|Firmicutes,24NT0@186801|Clostridia,3WQ50@541000|Ruminococcaceae	186801|Clostridia	S	Putative tranposon-transfer assisting protein	-	-	-	-	-	-	-	-	-	-	-	-	TTRAP
KFPFDFKC_01221	411483.FAEPRAA2165_00077	2.88e-80	238.0	28NID@1|root,2ZBYW@2|Bacteria,1V1SS@1239|Firmicutes,24GAZ@186801|Clostridia,3WP5B@541000|Ruminococcaceae	186801|Clostridia	S	Cysteine-rich VLP	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_VLP
KFPFDFKC_01222	97139.C824_03401	1.56e-263	729.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,2481D@186801|Clostridia,36E9W@31979|Clostridiaceae	186801|Clostridia	U	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
KFPFDFKC_01223	411468.CLOSCI_00087	7.44e-66	201.0	296J0@1|root,2ZTUJ@2|Bacteria,1V3IP@1239|Firmicutes,24H9K@186801|Clostridia,22070@1506553|Lachnoclostridium	186801|Clostridia	S	COG NOG22231 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	MobC
KFPFDFKC_01224	272563.CD630_11000	2.59e-63	195.0	COG1396@1|root,COG1396@2|Bacteria,1V58U@1239|Firmicutes,24HKI@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
KFPFDFKC_01225	1121115.AXVN01000026_gene1030	1.27e-32	114.0	COG3177@1|root,COG3177@2|Bacteria	2|Bacteria	D	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_17
KFPFDFKC_01226	397287.C807_02624	2.46e-149	421.0	COG0745@1|root,COG0745@2|Bacteria,1TT12@1239|Firmicutes,24AB1@186801|Clostridia,27K5E@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
KFPFDFKC_01227	397287.C807_02625	5.5e-209	582.0	COG0642@1|root,COG2205@2|Bacteria,1TT7F@1239|Firmicutes,247UJ@186801|Clostridia,27J5S@186928|unclassified Lachnospiraceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
KFPFDFKC_01228	397287.C807_02626	1.08e-147	417.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,27J1B@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
KFPFDFKC_01229	1226325.HMPREF1548_01394	0.0	1157.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,36DMM@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
KFPFDFKC_01230	411468.CLOSCI_00078	6.26e-96	280.0	COG1595@1|root,COG1595@2|Bacteria,1W79R@1239|Firmicutes,25MZX@186801|Clostridia,223HH@1506553|Lachnoclostridium	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
KFPFDFKC_01231	411468.CLOSCI_00077	1.05e-53	168.0	2AJW5@1|root,32RUV@2|Bacteria,1VA55@1239|Firmicutes,25E1F@186801|Clostridia	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
KFPFDFKC_01232	861454.HMPREF9099_02769	0.0	1061.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,27J4S@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Domain of unknown function (DUF4368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
KFPFDFKC_01233	622312.ROSEINA2194_01655	1.23e-38	142.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
KFPFDFKC_01234	622312.ROSEINA2194_01654	5.58e-53	167.0	2DMSX@1|root,32TG6@2|Bacteria,1VCKS@1239|Firmicutes,24P39@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01235	622312.ROSEINA2194_01652	0.0	1272.0	COG1199@1|root,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,25C6H@186801|Clostridia	186801|Clostridia	L	helicase involved in DNA repair and perhaps also replication	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Helicase_C_2
KFPFDFKC_01236	622312.ROSEINA2194_02825	9.98e-221	613.0	COG3039@1|root,COG3039@2|Bacteria,1TSDW@1239|Firmicutes,249M5@186801|Clostridia	186801|Clostridia	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
KFPFDFKC_01239	622312.ROSEINA2194_01646	6.86e-145	414.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
KFPFDFKC_01240	1469948.JPNB01000001_gene2441	4.22e-18	79.0	COG1595@1|root,COG1595@2|Bacteria,1VCH5@1239|Firmicutes,25GTE@186801|Clostridia,36MXN@31979|Clostridiaceae	186801|Clostridia	K	RNA polymerase sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4
KFPFDFKC_01241	622312.ROSEINA2194_01645	2.17e-51	164.0	COG1191@1|root,COG1191@2|Bacteria,1VJ1U@1239|Firmicutes,24I8V@186801|Clostridia	186801|Clostridia	K	sigma factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4
KFPFDFKC_01242	622312.ROSEINA2194_01642	2.47e-291	797.0	COG3290@1|root,COG3290@2|Bacteria,1V46S@1239|Firmicutes,24KBY@186801|Clostridia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
KFPFDFKC_01243	622312.ROSEINA2194_01641	4.33e-135	384.0	COG3279@1|root,COG3279@2|Bacteria,1V1JI@1239|Firmicutes,25BT0@186801|Clostridia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
KFPFDFKC_01244	1163671.JAGI01000002_gene3494	4.8e-41	139.0	2EBMR@1|root,335MY@2|Bacteria,1VHUF@1239|Firmicutes,24VP4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01246	585394.RHOM_09030	6.13e-219	627.0	COG0079@1|root,COG2082@1|root,COG0079@2|Bacteria,COG2082@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia	186801|Clostridia	E	PFAM Aminotransferase class I and II	cobD_2	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
KFPFDFKC_01247	622312.ROSEINA2194_01855	9.6e-168	481.0	COG1903@1|root,COG1903@2|Bacteria,1TQ3M@1239|Firmicutes,248AK@186801|Clostridia	186801|Clostridia	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
KFPFDFKC_01248	622312.ROSEINA2194_01854	5.63e-136	390.0	COG2875@1|root,COG2875@2|Bacteria,1TP6J@1239|Firmicutes,248IZ@186801|Clostridia	186801|Clostridia	H	precorrin-4 C(11)-methyltransferase	cobM	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
KFPFDFKC_01249	1469948.JPNB01000001_gene2323	5.74e-89	283.0	COG2073@1|root,COG2073@2|Bacteria,1TPYM@1239|Firmicutes,247JW@186801|Clostridia,36DM5@31979|Clostridiaceae	186801|Clostridia	H	Cobalamin biosynthesis protein cbiG	cbiG	-	3.7.1.12	ko:K02189	ko00860,ko01100,map00860,map01100	-	R07772	RC01545,RC02097	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS15705	CbiG_C,CbiG_N,CbiG_mid
KFPFDFKC_01250	1120746.CCNL01000008_gene554	1.99e-128	370.0	COG1010@1|root,COG1010@2|Bacteria	2|Bacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cobJ	-	2.1.1.131,2.1.1.133,2.1.1.271,3.7.1.12,6.3.5.10	ko:K02232,ko:K05934,ko:K05936,ko:K13541	ko00860,ko01100,map00860,map01100	M00122	R05180,R05181,R05225,R05809,R05810,R07772	RC00003,RC00010,RC01293,RC01294,RC01302,RC01545,RC02049,RC02097,RC03471	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiC,TP_methylase
KFPFDFKC_01251	1120746.CCNL01000008_gene555	5.68e-239	685.0	COG2099@1|root,COG2241@1|root,COG2242@1|root,COG2099@2|Bacteria,COG2241@2|Bacteria,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	cobK	-	1.3.1.106,1.3.1.54,1.3.1.76,2.1.1.131,2.1.1.132,2.1.1.196,2.1.1.289,3.7.1.12,4.99.1.4	ko:K00595,ko:K02191,ko:K02304,ko:K03399,ko:K05895,ko:K05934,ko:K13541	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947,R05149,R05150,R05180,R05809,R05812,R05813,R07772,R07774,R07775	RC00003,RC01012,RC01034,RC01279,RC01280,RC01293,RC01545,RC02052,RC02053,RC02054,RC02097,RC03471	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15725	CbiJ,Methyltransf_31,TP_methylase
KFPFDFKC_01252	397290.C810_02927	1.76e-181	526.0	COG1797@1|root,COG2158@1|root,COG1797@2|Bacteria,COG2158@2|Bacteria,1TNY2@1239|Firmicutes,247PU@186801|Clostridia,27IYT@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
KFPFDFKC_01253	1120746.CCNL01000008_gene565	3.97e-96	288.0	COG2243@1|root,COG2243@2|Bacteria	2|Bacteria	H	precorrin-2 c20-methyltransferase	cobI	-	2.1.1.130,2.1.1.151,4.99.1.3	ko:K02190,ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05807,R05808	RC00003,RC01012,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
KFPFDFKC_01254	585394.RHOM_08970	4.02e-39	131.0	COG2158@1|root,COG2158@2|Bacteria	2|Bacteria	S	Cysteine-rich small domain	cbiA	-	-	ko:K07162	-	-	-	-	ko00000	-	-	-	zf-like
KFPFDFKC_01256	585394.RHOM_04810	8.84e-62	201.0	COG3773@1|root,COG3773@2|Bacteria,1VHG1@1239|Firmicutes,24SYE@186801|Clostridia	186801|Clostridia	M	COG3773 Cell wall hydrolyses involved in spore germination	-	-	3.5.1.28	ko:K01449	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Hydrolase_2
KFPFDFKC_01257	1163671.JAGI01000002_gene2184	1.01e-53	184.0	COG0037@1|root,COG0607@1|root,COG0037@2|Bacteria,COG0607@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia,36DIN@31979|Clostridiaceae	186801|Clostridia	H	Belongs to the TtcA family	ttcA	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3,Rhodanese
KFPFDFKC_01258	585394.RHOM_05970	1.64e-210	601.0	COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg,SnoaL_3
KFPFDFKC_01259	397290.C810_02248	5.99e-21	84.0	29VDD@1|root,325Y2@2|Bacteria,1UHHD@1239|Firmicutes,25JIV@186801|Clostridia,27SCF@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01260	397290.C810_02249	1.73e-35	122.0	COG5577@1|root,COG5577@2|Bacteria,1TU9X@1239|Firmicutes,25IH5@186801|Clostridia,27S9B@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Coat F domain	-	-	-	-	-	-	-	-	-	-	-	-	Coat_F
KFPFDFKC_01261	585394.RHOM_05920	3.92e-137	409.0	COG1132@1|root,COG1132@2|Bacteria,1UHQP@1239|Firmicutes,25E4H@186801|Clostridia	186801|Clostridia	V	abc transporter atp-binding protein	cydC	-	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
KFPFDFKC_01262	411489.CLOL250_01927	0.0	895.0	COG1757@1|root,COG1757@2|Bacteria,1TP8A@1239|Firmicutes,247V4@186801|Clostridia,36EFF@31979|Clostridiaceae	186801|Clostridia	C	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
KFPFDFKC_01263	515620.EUBELI_20602	1.2e-51	164.0	2CG7V@1|root,32S3C@2|Bacteria,1UIG6@1239|Firmicutes,25EMK@186801|Clostridia,25ZVA@186806|Eubacteriaceae	186801|Clostridia	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4298,Dabb
KFPFDFKC_01264	515620.EUBELI_20270	3.85e-86	256.0	COG2606@1|root,COG2606@2|Bacteria,1V3MU@1239|Firmicutes,24HH2@186801|Clostridia,25W9B@186806|Eubacteriaceae	186801|Clostridia	S	Aminoacyl-tRNA editing domain	EbsC	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
KFPFDFKC_01265	1280681.AUJZ01000005_gene3017	3.01e-110	334.0	COG0639@1|root,COG0639@2|Bacteria,1V2F7@1239|Firmicutes,24H5G@186801|Clostridia,4BWBP@830|Butyrivibrio	186801|Clostridia	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
KFPFDFKC_01266	1408436.JHXY01000019_gene1391	5.52e-137	396.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,24ADT@186801|Clostridia,25W58@186806|Eubacteriaceae	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
KFPFDFKC_01267	411467.BACCAP_02128	4.25e-89	268.0	28N6T@1|root,2ZBBM@2|Bacteria,1TS9F@1239|Firmicutes,24DPE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01268	397287.C807_02675	4.68e-53	172.0	COG5658@1|root,COG5658@2|Bacteria,1VB6E@1239|Firmicutes,24MSY@186801|Clostridia,27NNV@186928|unclassified Lachnospiraceae	186801|Clostridia	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	SdpI
KFPFDFKC_01269	1280694.AUJQ01000010_gene2535	3.03e-151	431.0	COG1533@1|root,COG1533@2|Bacteria,1TSS2@1239|Firmicutes,248SB@186801|Clostridia,3NI14@46205|Pseudobutyrivibrio	186801|Clostridia	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
KFPFDFKC_01270	1226325.HMPREF1548_06783	1.2e-131	377.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,36DZG@31979|Clostridiaceae	186801|Clostridia	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
KFPFDFKC_01271	1232449.BAHV02000002_gene85	1.61e-151	468.0	COG5002@1|root,COG5002@2|Bacteria,1UM03@1239|Firmicutes,24F2S@186801|Clostridia,26CT2@186813|unclassified Clostridiales	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
KFPFDFKC_01272	1226325.HMPREF1548_02292	1.37e-237	680.0	COG3534@1|root,COG3534@2|Bacteria,1TPG2@1239|Firmicutes,24AVP@186801|Clostridia	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-L-AF_C,CBM_4_9,Cadherin-like,Laminin_G_3
KFPFDFKC_01273	1298920.KI911353_gene1794	3.25e-76	261.0	COG2972@1|root,COG2972@2|Bacteria,1VS0D@1239|Firmicutes,24YHS@186801|Clostridia,221U8@1506553|Lachnoclostridium	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase
KFPFDFKC_01274	697281.Mahau_2735	3.3e-43	169.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TV2J@1239|Firmicutes,249HW@186801|Clostridia,42J1B@68295|Thermoanaerobacterales	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
KFPFDFKC_01275	1298920.KI911353_gene1795	3.66e-171	496.0	COG1653@1|root,COG1653@2|Bacteria,1V5R7@1239|Firmicutes,25BSW@186801|Clostridia,221PP@1506553|Lachnoclostridium	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
KFPFDFKC_01276	610130.Closa_1668	8.67e-136	394.0	COG1175@1|root,COG1175@2|Bacteria,1V0JI@1239|Firmicutes,25C5R@186801|Clostridia,2200H@1506553|Lachnoclostridium	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
KFPFDFKC_01277	1298920.KI911353_gene1797	3.04e-134	389.0	COG0395@1|root,COG0395@2|Bacteria,1V2Q1@1239|Firmicutes,24A8E@186801|Clostridia,2202Q@1506553|Lachnoclostridium	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
KFPFDFKC_01279	1274374.CBLK010000070_gene1204	2.37e-233	697.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,4HB2V@91061|Bacilli,26SFU@186822|Paenibacillaceae	1239|Firmicutes	G	Alpha-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
KFPFDFKC_01280	658086.HMPREF0994_06533	0.0	962.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,27IHI@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolases family 2	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
KFPFDFKC_01281	1226325.HMPREF1548_05939	6.25e-36	122.0	COG1918@1|root,COG1918@2|Bacteria,1VEYA@1239|Firmicutes,24QKX@186801|Clostridia,36MP8@31979|Clostridiaceae	186801|Clostridia	P	Fe2 transport system protein A	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
KFPFDFKC_01282	585394.RHOM_03450	7.15e-43	140.0	COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,24QKE@186801|Clostridia	186801|Clostridia	P	Fe2 transport system protein A	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
KFPFDFKC_01283	585394.RHOM_03455	0.0	1303.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
KFPFDFKC_01284	1235799.C818_03332	7.94e-17	72.4	2C6KI@1|root,33J10@2|Bacteria,1VKBK@1239|Firmicutes,24UUY@186801|Clostridia,27Q8P@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Virus attachment protein p12 family	-	-	-	-	-	-	-	-	-	-	-	-	P12
KFPFDFKC_01285	1304866.K413DRAFT_2073	9.95e-66	204.0	COG0735@1|root,COG0735@2|Bacteria,1V6DP@1239|Firmicutes,24K9H@186801|Clostridia,36IEH@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
KFPFDFKC_01286	585394.RHOM_10590	8.73e-36	123.0	COG2608@1|root,COG2608@2|Bacteria,1VETC@1239|Firmicutes,24QJU@186801|Clostridia	186801|Clostridia	P	mercury ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	HMA
KFPFDFKC_01287	658088.HMPREF0987_01444	0.0	1464.0	COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,248YP@186801|Clostridia,27I5Y@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Putative carbohydrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36
KFPFDFKC_01288	658088.HMPREF0987_01443	0.0	1320.0	COG3459@1|root,COG3459@2|Bacteria,1UYFP@1239|Firmicutes,24A8A@186801|Clostridia,27J08@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36
KFPFDFKC_01289	585394.RHOM_05815	1.57e-154	436.0	COG2207@1|root,COG2207@2|Bacteria,1UZ5U@1239|Firmicutes,24DJM@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC
KFPFDFKC_01290	622312.ROSEINA2194_02494	1.15e-261	726.0	COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
KFPFDFKC_01291	622312.ROSEINA2194_02493	2.03e-193	540.0	COG1175@1|root,COG1175@2|Bacteria,1TS63@1239|Firmicutes,2489M@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport systems permease components	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
KFPFDFKC_01292	622312.ROSEINA2194_02492	2.1e-172	484.0	COG0395@1|root,COG0395@2|Bacteria,1TS0R@1239|Firmicutes,248UX@186801|Clostridia	186801|Clostridia	P	ABC-type sugar transport system, permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
KFPFDFKC_01293	903814.ELI_3973	4.26e-89	271.0	COG0300@1|root,COG0300@2|Bacteria,1V3UX@1239|Firmicutes,25B0Y@186801|Clostridia,25WEG@186806|Eubacteriaceae	186801|Clostridia	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
KFPFDFKC_01294	622312.ROSEINA2194_01770	1.55e-65	201.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	ziaR	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
KFPFDFKC_01295	585394.RHOM_03480	3.73e-40	133.0	COG2608@1|root,COG2608@2|Bacteria,1VEM6@1239|Firmicutes,24R22@186801|Clostridia	186801|Clostridia	P	Heavy metal-associated domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HMA
KFPFDFKC_01296	622312.ROSEINA2194_01772	0.0	970.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
KFPFDFKC_01297	411902.CLOBOL_05591	2.48e-34	121.0	2E5VW@1|root,330JY@2|Bacteria,1VEZ5@1239|Firmicutes,24R14@186801|Clostridia,2218J@1506553|Lachnoclostridium	186801|Clostridia	S	H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01298	585394.RHOM_10175	0.0	1105.0	COG2217@1|root,COG2217@2|Bacteria,1TPB8@1239|Firmicutes,247RZ@186801|Clostridia	186801|Clostridia	P	heavy metal translocating P-type ATPase	copA_1	-	-	ko:K12950	-	-	-	-	ko00000,ko01000	3.A.3.32	-	-	E1-E2_ATPase,Hydrolase
KFPFDFKC_01299	622312.ROSEINA2194_02134	1.13e-36	145.0	2CB93@1|root,30P4I@2|Bacteria,1V581@1239|Firmicutes,24IR0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01300	483218.BACPEC_02952	1.9e-84	264.0	COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,249J1@186801|Clostridia,26BFC@186813|unclassified Clostridiales	186801|Clostridia	S	Serine hydrolase (FSH1)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	FSH1,Hydrolase_4,Peptidase_S9
KFPFDFKC_01301	483218.BACPEC_02951	7.37e-124	369.0	COG2199@1|root,COG2199@2|Bacteria,1VBH6@1239|Firmicutes,24P8P@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
KFPFDFKC_01302	585394.RHOM_09350	1.33e-299	823.0	COG1143@1|root,COG4624@1|root,COG1143@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia	186801|Clostridia	C	Iron only hydrogenase large subunit, C-terminal domain	-	-	1.12.7.2	ko:K00533	-	-	R00019	-	ko00000,ko01000	-	-	-	Fe_hyd_lg_C,Fer4
KFPFDFKC_01303	1280668.ATVT01000014_gene124	5.34e-146	445.0	COG2801@1|root,COG2801@2|Bacteria,1TRP2@1239|Firmicutes,25PZ8@186801|Clostridia,4BYF1@830|Butyrivibrio	186801|Clostridia	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	Mu-transpos_C,rve
KFPFDFKC_01305	585394.RHOM_07605	8.89e-129	368.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
KFPFDFKC_01306	622312.ROSEINA2194_03746	1.77e-188	527.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
KFPFDFKC_01307	585394.RHOM_07615	3.01e-61	194.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
KFPFDFKC_01308	585394.RHOM_07620	6.77e-180	510.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
KFPFDFKC_01309	622312.ROSEINA2194_03750	1.03e-124	361.0	COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,24GDV@186801|Clostridia	186801|Clostridia	S	S4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S4
KFPFDFKC_01310	585394.RHOM_07630	3.65e-79	240.0	COG1799@1|root,COG1799@2|Bacteria,1V5NF@1239|Firmicutes,25CNH@186801|Clostridia	186801|Clostridia	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
KFPFDFKC_01311	585394.RHOM_07635	9.58e-138	392.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
KFPFDFKC_01312	622312.ROSEINA2194_03753	3.7e-213	602.0	COG0845@1|root,COG0845@2|Bacteria,1TRN9@1239|Firmicutes,248G2@186801|Clostridia	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01313	585394.RHOM_07645	3.66e-37	125.0	COG2155@1|root,COG2155@2|Bacteria,1VEQJ@1239|Firmicutes,24QKW@186801|Clostridia	186801|Clostridia	S	Conserved protein	-	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
KFPFDFKC_01314	585394.RHOM_07650	6.25e-75	226.0	COG0593@1|root,COG0593@2|Bacteria,1VAFE@1239|Firmicutes,25E3U@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01315	585394.RHOM_07655	6.87e-164	466.0	COG1686@1|root,COG1686@2|Bacteria,1TU06@1239|Firmicutes,25B23@186801|Clostridia	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
KFPFDFKC_01316	585394.RHOM_07660	8.95e-91	265.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia	186801|Clostridia	G	methylglyoxal synthase	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
KFPFDFKC_01317	585394.RHOM_07665	6.81e-197	553.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,247WS@186801|Clostridia	186801|Clostridia	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
KFPFDFKC_01318	622312.ROSEINA2194_03759	1.23e-16	73.6	COG0851@1|root,COG0851@2|Bacteria	2|Bacteria	D	regulation of division septum assembly	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
KFPFDFKC_01319	585394.RHOM_07675	4.57e-120	351.0	COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,249BB@186801|Clostridia	186801|Clostridia	D	Belongs to the ParA family	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA,ParA
KFPFDFKC_01320	585394.RHOM_07685	0.0	1333.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,2480Z@186801|Clostridia	186801|Clostridia	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
KFPFDFKC_01321	585394.RHOM_07690	1.4e-91	271.0	COG2891@1|root,COG2891@2|Bacteria,1V1EJ@1239|Firmicutes,24GF4@186801|Clostridia	186801|Clostridia	M	rod shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
KFPFDFKC_01322	585394.RHOM_07695	1.83e-147	421.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
KFPFDFKC_01323	585394.RHOM_07700	4.99e-213	592.0	COG1077@1|root,COG1077@2|Bacteria,1TPVU@1239|Firmicutes,248CM@186801|Clostridia	186801|Clostridia	D	Cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
KFPFDFKC_01324	585394.RHOM_07705	2.19e-91	275.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia	186801|Clostridia	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
KFPFDFKC_01326	585394.RHOM_07710	7.2e-283	776.0	COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,247Y4@186801|Clostridia	186801|Clostridia	P	aluminum resistance protein	ynbB	-	-	-	-	-	-	-	-	-	-	-	Met_gamma_lyase
KFPFDFKC_01327	622312.ROSEINA2194_03770	1.95e-179	505.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia	186801|Clostridia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
KFPFDFKC_01328	622312.ROSEINA2194_03771	0.0	909.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
KFPFDFKC_01329	1235802.C823_03200	1.45e-100	298.0	COG1351@1|root,COG1351@2|Bacteria,1TRAA@1239|Firmicutes,249DJ@186801|Clostridia,25V4I@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
KFPFDFKC_01330	585394.RHOM_07725	0.0	1497.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
KFPFDFKC_01331	585394.RHOM_07730	9.92e-253	709.0	COG2509@1|root,COG2509@2|Bacteria,1TPBW@1239|Firmicutes,247TR@186801|Clostridia	186801|Clostridia	H	'oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	HI0933_like,NAD_binding_8,Pyr_redox_2
KFPFDFKC_01332	622312.ROSEINA2194_03775	2.33e-175	503.0	COG2081@1|root,COG2081@2|Bacteria,1TR7U@1239|Firmicutes,2497W@186801|Clostridia	186801|Clostridia	S	Flavoprotein family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
KFPFDFKC_01333	397288.C806_02312	2.5e-10	61.6	2EJV3@1|root,33DJR@2|Bacteria,1VKNR@1239|Firmicutes,24UH1@186801|Clostridia,27TPQ@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01334	585394.RHOM_07745	1.11e-259	728.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia	186801|Clostridia	S	Stage V sporulation protein B	spoVB1	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
KFPFDFKC_01335	622312.ROSEINA2194_03780	1.08e-87	260.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia	186801|Clostridia	F	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
KFPFDFKC_01336	585394.RHOM_07755	8.91e-110	334.0	COG1480@1|root,COG1480@2|Bacteria	2|Bacteria	O	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	-
KFPFDFKC_01337	585394.RHOM_07760	7.05e-207	576.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia	186801|Clostridia	T	phosphate starvation-inducible protein	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
KFPFDFKC_01338	585394.RHOM_07765	4.98e-162	469.0	COG0561@1|root,COG0561@2|Bacteria,1TR3N@1239|Firmicutes,24ACD@186801|Clostridia	186801|Clostridia	S	Sporulation protein YqfD	yqfD	-	-	ko:K06438	-	-	-	-	ko00000	-	-	-	YqfD
KFPFDFKC_01339	1235790.C805_01829	1.94e-29	107.0	2B2ZJ@1|root,31VKQ@2|Bacteria,1TVEP@1239|Firmicutes,25NEX@186801|Clostridia,25XCH@186806|Eubacteriaceae	186801|Clostridia	S	YabP family	-	-	-	-	-	-	-	-	-	-	-	-	YabP
KFPFDFKC_01340	585394.RHOM_07775	7.43e-234	652.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,24848@186801|Clostridia	186801|Clostridia	F	pyrimidine-nucleoside phosphorylase	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08925	Glycos_trans_3N,Glycos_transf_3,PYNP_C
KFPFDFKC_01341	411490.ANACAC_03749	6.72e-23	97.4	COG2068@1|root,COG2068@2|Bacteria,1VA0F@1239|Firmicutes,24NSX@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
KFPFDFKC_01342	622312.ROSEINA2194_03787	0.0	1268.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia	186801|Clostridia	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	xdhD	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
KFPFDFKC_01343	622312.ROSEINA2194_03788	7.67e-87	257.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24HQN@186801|Clostridia	186801|Clostridia	C	aerobic-type carbon monoxide dehydrogenase, small subunit CoxS	hcrC	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
KFPFDFKC_01344	622312.ROSEINA2194_03789	4.99e-117	343.0	COG1319@1|root,COG1319@2|Bacteria,1TSNH@1239|Firmicutes,24A57@186801|Clostridia	186801|Clostridia	C	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
KFPFDFKC_01345	33035.JPJF01000004_gene1973	1.3e-53	182.0	COG2340@1|root,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,24BAQ@186801|Clostridia	186801|Clostridia	V	PFAM SCP-like extracellular	safA	-	-	-	-	-	-	-	-	-	-	-	CAP,LysM
KFPFDFKC_01346	553973.CLOHYLEM_07594	6.07e-135	384.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,24899@186801|Clostridia,21Y4Q@1506553|Lachnoclostridium	186801|Clostridia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
KFPFDFKC_01347	742765.HMPREF9457_00537	5.47e-192	544.0	COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,247R4@186801|Clostridia,27WJP@189330|Dorea	186801|Clostridia	P	Voltage gated chloride channel	eriC	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
KFPFDFKC_01348	1256908.HMPREF0373_02751	1.64e-290	802.0	COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,248NQ@186801|Clostridia,25V4N@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21.2	-	-	SSF
KFPFDFKC_01349	1395587.P364_0126160	2.24e-190	548.0	COG3507@1|root,COG3507@2|Bacteria,1UY12@1239|Firmicutes,4HEUT@91061|Bacilli,27497@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.37,3.2.1.55	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	-	R01433,R01762	RC00467	ko00000,ko00001,ko01000	-	GH43,GH51	-	Glyco_hydro_43
KFPFDFKC_01350	585394.RHOM_07785	3.32e-81	244.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia	186801|Clostridia	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
KFPFDFKC_01352	622312.ROSEINA2194_03792	3.7e-104	304.0	COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,249VC@186801|Clostridia	186801|Clostridia	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis	xpt	-	2.4.2.22	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
KFPFDFKC_01353	622312.ROSEINA2194_03801	9.73e-96	297.0	COG0457@1|root,COG0457@2|Bacteria,1UZDE@1239|Firmicutes,2491Z@186801|Clostridia	186801|Clostridia	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Fn3_assoc,TPR_16,TPR_19,TPR_8,zinc_ribbon_2
KFPFDFKC_01354	585394.RHOM_07810	0.0	1000.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia	186801|Clostridia	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
KFPFDFKC_01355	585394.RHOM_07815	0.0	1089.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia	186801|Clostridia	D	FtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
KFPFDFKC_01356	585394.RHOM_07820	8e-150	428.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
KFPFDFKC_01357	585394.RHOM_07825	3.67e-125	360.0	COG0740@1|root,COG0740@2|Bacteria,1TPX2@1239|Firmicutes,249QX@186801|Clostridia	186801|Clostridia	OU	Protease subunit of ATP-dependent	tepA	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
KFPFDFKC_01358	585394.RHOM_07830	0.0	920.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
KFPFDFKC_01359	585394.RHOM_07835	4.31e-150	424.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia	186801|Clostridia	K	transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
KFPFDFKC_01360	585394.RHOM_07845	2.16e-70	213.0	COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,24JE1@186801|Clostridia	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	ndoA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
KFPFDFKC_01361	622312.ROSEINA2194_03813	1.54e-212	595.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
KFPFDFKC_01362	585394.RHOM_07850	1.53e-177	516.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
KFPFDFKC_01363	585394.RHOM_07855	2.74e-139	395.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia	186801|Clostridia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
KFPFDFKC_01364	585394.RHOM_07860	0.0	969.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia	186801|Clostridia	S	Abc transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
KFPFDFKC_01365	585394.RHOM_07865	5.04e-278	761.0	COG0538@1|root,COG0538@2|Bacteria,1TSKB@1239|Firmicutes,247KX@186801|Clostridia	186801|Clostridia	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
KFPFDFKC_01366	585394.RHOM_07870	3.78e-126	362.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24E6I@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
KFPFDFKC_01367	585394.RHOM_07875	0.0	923.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2495J@186801|Clostridia	186801|Clostridia	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0036440,GO:0046912,GO:0050450	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS03250	HMGL-like
KFPFDFKC_01370	585394.RHOM_07895	4.71e-51	163.0	2EJ0U@1|root,33CS0@2|Bacteria,1VKD6@1239|Firmicutes,24W6Q@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01371	622312.ROSEINA2194_03829	2.17e-35	122.0	2BC9Q@1|root,325UU@2|Bacteria,1URUY@1239|Firmicutes,24WWT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01372	585394.RHOM_07905	1.66e-212	598.0	COG3391@1|root,COG5492@1|root,COG3391@2|Bacteria,COG5492@2|Bacteria,1TR9I@1239|Firmicutes,24CXQ@186801|Clostridia	186801|Clostridia	M	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new
KFPFDFKC_01373	585394.RHOM_07910	0.0	1261.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia	186801|Clostridia	J	elongation factor g	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
KFPFDFKC_01374	585394.RHOM_07915	1.27e-187	530.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia	186801|Clostridia	E	prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
KFPFDFKC_01376	1408312.JNJS01000006_gene701	5.48e-34	130.0	COG5434@1|root,COG5434@2|Bacteria,1TSA5@1239|Firmicutes,24B0W@186801|Clostridia,3NHBQ@46205|Pseudobutyrivibrio	186801|Clostridia	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01378	585394.RHOM_07945	6.84e-230	635.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia	186801|Clostridia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
KFPFDFKC_01379	1256908.HMPREF0373_02472	0.0	1296.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,25UVH@186806|Eubacteriaceae	186801|Clostridia	J	phenylalanyl-tRNA synthetase (beta subunit)	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
KFPFDFKC_01380	483218.BACPEC_01341	7.26e-209	581.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,267UI@186813|unclassified Clostridiales	186801|Clostridia	J	Aminoacyl tRNA synthetase class II, N-terminal domain	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
KFPFDFKC_01381	585394.RHOM_07960	2.15e-148	423.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,24A2Q@186801|Clostridia	186801|Clostridia	H	Belongs to the UPF0761 family	yihY	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
KFPFDFKC_01382	585394.RHOM_07965	4.56e-261	747.0	COG2385@1|root,COG2385@2|Bacteria,1UW6J@1239|Firmicutes,24CYM@186801|Clostridia	186801|Clostridia	D	SpoIID LytB domain protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
KFPFDFKC_01383	1256908.HMPREF0373_02866	3.38e-133	392.0	COG0194@1|root,COG4502@1|root,COG0194@2|Bacteria,COG4502@2|Bacteria,1V87A@1239|Firmicutes,24SD2@186801|Clostridia	186801|Clostridia	F	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_kin,NT5C
KFPFDFKC_01384	411474.COPEUT_01787	0.0	991.0	COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia	186801|Clostridia	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
KFPFDFKC_01385	585394.RHOM_14095	3.01e-72	233.0	COG0840@1|root,COG0840@2|Bacteria,1TY0J@1239|Firmicutes,24DGH@186801|Clostridia	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
KFPFDFKC_01386	585394.RHOM_14090	4.06e-179	507.0	COG3287@1|root,COG3287@2|Bacteria,1UK57@1239|Firmicutes,24D5K@186801|Clostridia	186801|Clostridia	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
KFPFDFKC_01387	585394.RHOM_07975	2.53e-69	212.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,24JEM@186801|Clostridia	186801|Clostridia	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
KFPFDFKC_01388	622312.ROSEINA2194_03850	5.45e-285	783.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia	186801|Clostridia	C	citrate synthase	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
KFPFDFKC_01389	585394.RHOM_07985	3.89e-233	658.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
KFPFDFKC_01390	585394.RHOM_07990	6.67e-141	400.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07775	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
KFPFDFKC_01391	622312.ROSEINA2194_03851	2.95e-42	141.0	2EH8T@1|root,33B0N@2|Bacteria,1VKIJ@1239|Firmicutes,24V3Q@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01392	585394.RHOM_08000	2.11e-59	186.0	COG4753@1|root,COG4753@2|Bacteria,1VAG0@1239|Firmicutes,24P6B@186801|Clostridia	186801|Clostridia	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_18,Response_reg
KFPFDFKC_01393	585394.RHOM_08005	1.46e-107	321.0	COG1406@1|root,COG1406@2|Bacteria,1V46M@1239|Firmicutes,24B3C@186801|Clostridia	186801|Clostridia	N	Chemotaxis phosphatase CheX	-	-	-	-	-	-	-	-	-	-	-	-	CheX
KFPFDFKC_01394	622312.ROSEINA2194_03854	3.56e-310	851.0	COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia	186801|Clostridia	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS16355	PALP,Thr_synth_N
KFPFDFKC_01395	585394.RHOM_08020	3.18e-127	369.0	28NT4@1|root,2ZBRW@2|Bacteria,1UXVI@1239|Firmicutes,24ABY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01396	483218.BACPEC_02992	5.09e-105	329.0	COG0840@1|root,COG0840@2|Bacteria,1TSW1@1239|Firmicutes,24B19@186801|Clostridia	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
KFPFDFKC_01397	1235802.C823_03008	3.14e-265	749.0	COG0840@1|root,COG1145@1|root,COG4624@1|root,COG0840@2|Bacteria,COG1145@2|Bacteria,COG4624@2|Bacteria,1TSVR@1239|Firmicutes,248TC@186801|Clostridia,25VKU@186806|Eubacteriaceae	186801|Clostridia	CNT	Iron only hydrogenase large subunit, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fe_hyd_lg_C,Fer4,Fer4_10,Fer4_7,MCPsignal
KFPFDFKC_01398	585394.RHOM_08335	1.03e-156	443.0	COG1036@1|root,COG2878@1|root,COG1036@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia	186801|Clostridia	C	electron transport complex, RnfABCDGE type, B subunit	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_13,Fer4_4,Fer4_9
KFPFDFKC_01399	585394.RHOM_08340	4.83e-123	352.0	COG4657@1|root,COG4657@2|Bacteria,1TS06@1239|Firmicutes,247UE@186801|Clostridia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
KFPFDFKC_01400	585394.RHOM_08345	9.91e-139	395.0	COG4660@1|root,COG4660@2|Bacteria,1TSE7@1239|Firmicutes,24972@186801|Clostridia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	iHN637.CLJU_RS05585	Rnf-Nqr
KFPFDFKC_01401	585394.RHOM_08350	3.91e-106	310.0	COG4659@1|root,COG4659@2|Bacteria,1V7R1@1239|Firmicutes,24JVM@186801|Clostridia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfG	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
KFPFDFKC_01402	585394.RHOM_08355	1.52e-185	520.0	COG4658@1|root,COG4658@2|Bacteria,1TQAY@1239|Firmicutes,247TM@186801|Clostridia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
KFPFDFKC_01403	585394.RHOM_08360	1.28e-278	766.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia	186801|Clostridia	C	Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4,Fer4_10,Fer4_7,Fer4_9,RnfC_N,SLBB
KFPFDFKC_01404	585394.RHOM_08365	7.82e-126	375.0	COG3359@1|root,COG3359@2|Bacteria,1U725@1239|Firmicutes,24A9V@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
KFPFDFKC_01405	397290.C810_00991	7.11e-35	153.0	COG4886@1|root,COG5492@1|root,COG4886@2|Bacteria,COG5492@2|Bacteria,1V32P@1239|Firmicutes,25FDC@186801|Clostridia,27UE2@186928|unclassified Lachnospiraceae	186801|Clostridia	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
KFPFDFKC_01406	585394.RHOM_08370	3.43e-165	464.0	COG1352@1|root,COG1352@2|Bacteria,1TPD8@1239|Firmicutes,24AQJ@186801|Clostridia	186801|Clostridia	NT	PFAM MCP methyltransferase, CheR-type	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
KFPFDFKC_01407	585394.RHOM_08375	1.19e-240	664.0	COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia	186801|Clostridia	J	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
KFPFDFKC_01408	585394.RHOM_08380	1.55e-151	432.0	COG0761@1|root,COG0761@2|Bacteria,1UHT7@1239|Firmicutes,25E67@186801|Clostridia	186801|Clostridia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB
KFPFDFKC_01409	585394.RHOM_08385	3.02e-128	367.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
KFPFDFKC_01410	622312.ROSEINA2194_00502	4.22e-222	621.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,247S5@186801|Clostridia	186801|Clostridia	S	Flavoprotein family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
KFPFDFKC_01411	585394.RHOM_08395	8.75e-193	538.0	COG1737@1|root,COG1737@2|Bacteria,1TP7H@1239|Firmicutes,248ZD@186801|Clostridia	186801|Clostridia	K	transcriptional regulator RpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
KFPFDFKC_01412	1235793.C809_02550	0.0	944.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,27IE8@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
KFPFDFKC_01413	585394.RHOM_08405	0.0	890.0	COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia	186801|Clostridia	C	carboxylase	oadA	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
KFPFDFKC_01414	585394.RHOM_08410	9.3e-254	698.0	COG1883@1|root,COG1883@2|Bacteria,1TPEP@1239|Firmicutes,248ET@186801|Clostridia	186801|Clostridia	C	decarboxylase beta subunit	gcdB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
KFPFDFKC_01415	622312.ROSEINA2194_00498	4.57e-53	169.0	COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia	186801|Clostridia	I	PFAM biotin lipoyl attachment domain-containing protein	gcdC	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
KFPFDFKC_01416	585394.RHOM_08420	3.7e-96	288.0	2DMIV@1|root,32RW6@2|Bacteria,1VAMW@1239|Firmicutes,24DVC@186801|Clostridia	186801|Clostridia	P	decarboxylase gamma	-	-	-	-	-	-	-	-	-	-	-	-	DUF3887,OAD_gamma
KFPFDFKC_01417	585394.RHOM_08425	3.69e-290	798.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia	186801|Clostridia	I	acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
KFPFDFKC_01418	585394.RHOM_08430	1.21e-176	504.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia	186801|Clostridia	M	Belongs to the peptidase S11 family	dacB2	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
KFPFDFKC_01419	585394.RHOM_08435	2.58e-109	317.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,24JW7@186801|Clostridia	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
KFPFDFKC_01420	585394.RHOM_08440	5.03e-141	402.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,249VW@186801|Clostridia	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
KFPFDFKC_01421	585394.RHOM_08445	3.25e-182	518.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,249B3@186801|Clostridia	186801|Clostridia	M	Belongs to the peptidase S11 family	dacF	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
KFPFDFKC_01422	585394.RHOM_08450	1.02e-276	767.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
KFPFDFKC_01423	585394.RHOM_08455	1.42e-150	432.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,249H1@186801|Clostridia	186801|Clostridia	O	Belongs to the peptidase S8 family	aprX	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
KFPFDFKC_01424	585394.RHOM_07130	9.28e-294	810.0	COG0589@1|root,COG0589@2|Bacteria,1TPUI@1239|Firmicutes,24826@186801|Clostridia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
KFPFDFKC_01425	585394.RHOM_07125	1.79e-110	323.0	COG0347@1|root,COG0347@2|Bacteria,1V65X@1239|Firmicutes,24HQ8@186801|Clostridia	186801|Clostridia	E	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01426	585394.RHOM_08460	0.0	1293.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
KFPFDFKC_01427	585394.RHOM_08465	3.3e-48	154.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
KFPFDFKC_01428	585394.RHOM_08470	4.16e-165	476.0	COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG3103@2|Bacteria,COG4991@2|Bacteria,1UBS0@1239|Firmicutes,25B2D@186801|Clostridia	186801|Clostridia	M	NlpC p60 family protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
KFPFDFKC_01429	585394.RHOM_08475	3.32e-171	483.0	COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,2484A@186801|Clostridia	186801|Clostridia	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
KFPFDFKC_01430	622312.ROSEINA2194_00453	9.45e-156	444.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,24B46@186801|Clostridia	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
KFPFDFKC_01431	585394.RHOM_08485	2.73e-167	474.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia	186801|Clostridia	J	domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
KFPFDFKC_01432	622312.ROSEINA2194_00455	5.93e-66	202.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
KFPFDFKC_01433	585394.RHOM_08495	0.0	1237.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
KFPFDFKC_01434	585394.RHOM_08500	1.52e-51	164.0	COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,24QP3@186801|Clostridia	186801|Clostridia	J	ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
KFPFDFKC_01435	585394.RHOM_08505	2.48e-49	158.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,24QSJ@186801|Clostridia	186801|Clostridia	K	Nucleic-acid-binding protein implicated in transcription termination	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
KFPFDFKC_01436	585394.RHOM_08510	1.76e-233	649.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
KFPFDFKC_01437	585394.RHOM_08515	3.83e-99	288.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,24N1G@186801|Clostridia	186801|Clostridia	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
KFPFDFKC_01439	596324.TREVI0001_2541	8.56e-46	152.0	28UBH@1|root,2ZGGW@2|Bacteria,2JB3E@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01440	1501230.ET33_20850	3.13e-09	65.9	COG0457@1|root,COG2214@1|root,COG0457@2|Bacteria,COG2214@2|Bacteria,1V0RY@1239|Firmicutes,4IREJ@91061|Bacilli,26UYS@186822|Paenibacillaceae	91061|Bacilli	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
KFPFDFKC_01441	585394.RHOM_11605	1.27e-162	484.0	COG0443@1|root,COG0443@2|Bacteria,1TQ6N@1239|Firmicutes,248UV@186801|Clostridia	186801|Clostridia	O	Belongs to the heat shock protein 70 family	-	-	-	ko:K04045	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
KFPFDFKC_01446	742765.HMPREF9457_03255	3.58e-145	422.0	COG2070@1|root,COG2070@2|Bacteria,1TPX1@1239|Firmicutes,247YZ@186801|Clostridia,27V3C@189330|Dorea	186801|Clostridia	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
KFPFDFKC_01447	622312.ROSEINA2194_03681	2.31e-234	645.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
KFPFDFKC_01448	585394.RHOM_08530	3.55e-173	486.0	COG2207@1|root,COG2207@2|Bacteria,1UZ0Q@1239|Firmicutes,24YIV@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
KFPFDFKC_01449	585394.RHOM_08535	7.79e-127	365.0	COG0613@1|root,COG0613@2|Bacteria,1V33M@1239|Firmicutes,24H1U@186801|Clostridia	186801|Clostridia	S	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP,PHP_C
KFPFDFKC_01450	622312.ROSEINA2194_01009	1.33e-70	213.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia	186801|Clostridia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
KFPFDFKC_01451	585394.RHOM_08100	2.92e-34	117.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
KFPFDFKC_01452	585394.RHOM_08105	1.78e-102	298.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,24FUS@186801|Clostridia	186801|Clostridia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
KFPFDFKC_01453	397288.C806_03378	2.27e-148	446.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,27KAK@186928|unclassified Lachnospiraceae	186801|Clostridia	NT	Four helix bundle sensory module for signal transduction	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal,dCache_1
KFPFDFKC_01454	622312.ROSEINA2194_02490	2.27e-58	185.0	COG0835@1|root,COG0835@2|Bacteria	2|Bacteria	NT	chemotaxis	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
KFPFDFKC_01455	585394.RHOM_08120	1.63e-143	412.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,248H2@186801|Clostridia	186801|Clostridia	S	PHP domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
KFPFDFKC_01456	585394.RHOM_08125	3.83e-130	376.0	COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,24PNN@186801|Clostridia	186801|Clostridia	S	HAD-superfamily hydrolase, subfamily IIB	yidA	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
KFPFDFKC_01457	585394.RHOM_08130	0.0	1181.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia	186801|Clostridia	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
KFPFDFKC_01458	622312.ROSEINA2194_01001	1.16e-277	769.0	COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,248EW@186801|Clostridia	186801|Clostridia	FP	Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
KFPFDFKC_01459	622312.ROSEINA2194_01000	1.26e-263	728.0	COG2607@1|root,COG2607@2|Bacteria,1TQDJ@1239|Firmicutes,2483S@186801|Clostridia	186801|Clostridia	E	ATPase (AAA superfamily)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
KFPFDFKC_01460	585394.RHOM_08145	1.67e-217	606.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1TPDN@1239|Firmicutes,248G7@186801|Clostridia	186801|Clostridia	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
KFPFDFKC_01461	622312.ROSEINA2194_00998	2.84e-103	313.0	COG0823@1|root,COG0823@2|Bacteria,1V60E@1239|Firmicutes,24I0N@186801|Clostridia	186801|Clostridia	U	Domain of unknown function (DUF5050)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5050
KFPFDFKC_01462	622312.ROSEINA2194_00997	0.0	2603.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,248YB@186801|Clostridia	186801|Clostridia	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
KFPFDFKC_01463	585394.RHOM_07195	9.54e-226	625.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
KFPFDFKC_01464	622312.ROSEINA2194_00995	5.71e-190	534.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia	186801|Clostridia	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
KFPFDFKC_01465	585394.RHOM_07185	7.79e-207	580.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
KFPFDFKC_01466	622312.ROSEINA2194_00993	1.79e-148	422.0	COG0575@1|root,COG0575@2|Bacteria,1UPNB@1239|Firmicutes,248BP@186801|Clostridia	186801|Clostridia	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
KFPFDFKC_01467	622312.ROSEINA2194_00992	3.33e-145	413.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
KFPFDFKC_01468	622312.ROSEINA2194_00991	3.3e-107	311.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia	186801|Clostridia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
KFPFDFKC_01469	585394.RHOM_07165	2.35e-151	427.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,247KR@186801|Clostridia	186801|Clostridia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
KFPFDFKC_01470	622312.ROSEINA2194_00989	1.24e-78	246.0	COG1664@1|root,COG1664@2|Bacteria,1TS93@1239|Firmicutes,24DZX@186801|Clostridia	186801|Clostridia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
KFPFDFKC_01471	622312.ROSEINA2194_00988	2.43e-148	427.0	COG0726@1|root,COG0726@2|Bacteria,1V1X7@1239|Firmicutes,25B6U@186801|Clostridia	186801|Clostridia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
KFPFDFKC_01472	1410626.JHXB01000007_gene2561	5.15e-83	258.0	COG2035@1|root,COG2035@2|Bacteria,1UYD5@1239|Firmicutes,24B08@186801|Clostridia,27KSJ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF368)	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
KFPFDFKC_01473	742738.HMPREF9460_03797	1.2e-220	628.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,2681R@186813|unclassified Clostridiales	186801|Clostridia	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
KFPFDFKC_01474	585394.RHOM_01235	0.0	910.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia	186801|Clostridia	G	Alpha amylase catalytic	-	-	3.2.1.1,3.2.1.10	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459
KFPFDFKC_01475	622312.ROSEINA2194_02238	1e-118	350.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UXKB@1239|Firmicutes,24DXK@186801|Clostridia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
KFPFDFKC_01476	585394.RHOM_07120	1.2e-195	545.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
KFPFDFKC_01477	585394.RHOM_07115	8.24e-164	459.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia	186801|Clostridia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
KFPFDFKC_01478	622312.ROSEINA2194_00984	4.9e-48	162.0	COG1559@1|root,COG1559@2|Bacteria,1VF4Y@1239|Firmicutes,24RCQ@186801|Clostridia	186801|Clostridia	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	-	-	-	-	-	-	-	-	-	-	-	-	YceG
KFPFDFKC_01479	585394.RHOM_07105	2.51e-57	189.0	COG3064@1|root,COG3064@2|Bacteria,1V968@1239|Firmicutes,24KD3@186801|Clostridia	186801|Clostridia	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01480	585394.RHOM_07100	1.1e-32	117.0	2ECFD@1|root,336DM@2|Bacteria,1VHDX@1239|Firmicutes,24TE9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01481	622312.ROSEINA2194_00979	2.28e-133	383.0	COG1191@1|root,COG1191@2|Bacteria,1TP9K@1239|Firmicutes,248M0@186801|Clostridia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
KFPFDFKC_01482	585394.RHOM_07090	3.96e-22	89.4	2E8TH@1|root,33348@2|Bacteria,1VJ8V@1239|Firmicutes,24SQI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01483	585394.RHOM_07085	4.4e-101	294.0	COG1871@1|root,COG1871@2|Bacteria,1V70X@1239|Firmicutes,24HH7@186801|Clostridia	186801|Clostridia	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
KFPFDFKC_01484	585394.RHOM_07080	1.03e-121	350.0	COG1776@1|root,COG1776@2|Bacteria,1UNKB@1239|Firmicutes,247MX@186801|Clostridia	186801|Clostridia	NT	Chemotaxis protein CheC, inhibitor of MCP methylation	cheC	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
KFPFDFKC_01485	585394.RHOM_07075	3.02e-79	238.0	COG0835@1|root,COG0835@2|Bacteria,1V4HH@1239|Firmicutes,24JV4@186801|Clostridia	186801|Clostridia	NT	PFAM CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
KFPFDFKC_01486	585394.RHOM_07070	0.0	1070.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1TPMS@1239|Firmicutes,24858@186801|Clostridia	186801|Clostridia	T	Signal transducing histidine kinase homodimeric	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
KFPFDFKC_01487	622312.ROSEINA2194_00972	1.6e-190	536.0	COG2201@1|root,COG2201@2|Bacteria,1TRHC@1239|Firmicutes,249FD@186801|Clostridia	186801|Clostridia	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
KFPFDFKC_01488	622312.ROSEINA2194_00971	1.57e-86	264.0	COG5581@1|root,COG5581@2|Bacteria,1VCR9@1239|Firmicutes	1239|Firmicutes	M	Flagellar protein YcgR	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR_2
KFPFDFKC_01489	1235790.C805_01994	6.5e-121	355.0	COG0455@1|root,COG0455@2|Bacteria,1TRZ5@1239|Firmicutes,24AIN@186801|Clostridia,25VBY@186806|Eubacteriaceae	186801|Clostridia	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	flhG	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	CbiA,ParA
KFPFDFKC_01490	585394.RHOM_07050	3.08e-195	553.0	COG1419@1|root,COG1419@2|Bacteria,1TSP7@1239|Firmicutes,249R1@186801|Clostridia	186801|Clostridia	N	PFAM GTP-binding signal recognition particle SRP54 G- domain	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
KFPFDFKC_01491	622312.ROSEINA2194_00968	0.0	1124.0	COG1298@1|root,COG1298@2|Bacteria,1TQBM@1239|Firmicutes,248F5@186801|Clostridia	186801|Clostridia	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
KFPFDFKC_01492	585394.RHOM_07040	3.9e-204	572.0	COG1377@1|root,COG1377@2|Bacteria,1TPRP@1239|Firmicutes,248N7@186801|Clostridia	186801|Clostridia	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401,ko:K13820	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1,Bac_export_2
KFPFDFKC_01493	622312.ROSEINA2194_00966	3.76e-134	385.0	COG1684@1|root,COG1684@2|Bacteria,1TRB2@1239|Firmicutes,24ECW@186801|Clostridia	186801|Clostridia	N	flagellar biosynthetic protein FliR	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
KFPFDFKC_01494	585394.RHOM_07030	2.4e-46	150.0	COG1987@1|root,COG1987@2|Bacteria,1VEHF@1239|Firmicutes,24QJR@186801|Clostridia	186801|Clostridia	N	Flagellar biosynthetic protein FliQ	fliQ	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
KFPFDFKC_01495	585394.RHOM_07025	1.93e-118	348.0	COG1338@1|root,COG1338@2|Bacteria,1TPIE@1239|Firmicutes,2487C@186801|Clostridia	186801|Clostridia	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
KFPFDFKC_01496	622312.ROSEINA2194_00963	2.66e-37	130.0	COG3190@1|root,COG3190@2|Bacteria,1VCEI@1239|Firmicutes,25FCZ@186801|Clostridia	186801|Clostridia	N	Flagellar biosynthesis protein, FliO	-	-	-	ko:K02418	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliO
KFPFDFKC_01497	585394.RHOM_07015	4.64e-76	227.0	COG2197@1|root,COG2197@2|Bacteria,1UIGG@1239|Firmicutes,25EMX@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
KFPFDFKC_01498	585394.RHOM_07010	6.25e-191	540.0	COG1776@1|root,COG1886@1|root,COG1776@2|Bacteria,COG1886@2|Bacteria,1TPT8@1239|Firmicutes,24821@186801|Clostridia	186801|Clostridia	N	Flagellar motor switch protein flin	fliN	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	CheC,FliMN_C
KFPFDFKC_01499	585394.RHOM_07005	3.2e-203	566.0	COG1868@1|root,COG1868@2|Bacteria,1TPTM@1239|Firmicutes,24AGV@186801|Clostridia	186801|Clostridia	N	flagellar motor switch protein FliM	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
KFPFDFKC_01500	585394.RHOM_07000	8.46e-67	208.0	2AHM3@1|root,317YZ@2|Bacteria,1V80Z@1239|Firmicutes,24M4F@186801|Clostridia	186801|Clostridia	S	Controls the rotational direction of flagella during chemotaxis	-	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
KFPFDFKC_01501	585394.RHOM_06995	2.02e-111	330.0	COG1360@1|root,COG1360@2|Bacteria,1V8KE@1239|Firmicutes,24GQQ@186801|Clostridia	186801|Clostridia	N	PFAM OmpA MotB domain protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
KFPFDFKC_01502	585394.RHOM_06990	4.53e-138	395.0	COG1291@1|root,COG1291@2|Bacteria,1TRH1@1239|Firmicutes,24AEJ@186801|Clostridia	186801|Clostridia	N	PFAM MotA TolQ ExbB proton channel	motA	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
KFPFDFKC_01503	1235790.C805_02008	5.92e-24	92.0	COG1582@1|root,COG1582@2|Bacteria,1VKHB@1239|Firmicutes,24RWI@186801|Clostridia,25XPE@186806|Eubacteriaceae	186801|Clostridia	N	Flagellar protein (FlbD)	flbD	-	-	ko:K02385	-	-	-	-	ko00000,ko02035	-	-	-	FlbD
KFPFDFKC_01504	585394.RHOM_06985	1.2e-224	639.0	COG1749@1|root,COG1749@2|Bacteria,1UHS7@1239|Firmicutes,247ZT@186801|Clostridia	186801|Clostridia	N	basal body rod protein	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
KFPFDFKC_01505	585394.RHOM_06980	8.74e-55	174.0	2E35U@1|root,32Y5R@2|Bacteria,1VEH9@1239|Firmicutes,24R2S@186801|Clostridia	186801|Clostridia	N	TIGRFAM flagellar operon protein	flg	-	-	-	-	-	-	-	-	-	-	-	Flagellar_put
KFPFDFKC_01506	585394.RHOM_06975	3.31e-78	243.0	COG1843@1|root,COG1843@2|Bacteria,1VF85@1239|Firmicutes,24QKD@186801|Clostridia	186801|Clostridia	N	Required for flagellar hook formation. May act as a scaffolding protein	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD
KFPFDFKC_01507	585394.RHOM_06970	1.66e-88	286.0	COG3144@1|root,COG3144@2|Bacteria,1V4YB@1239|Firmicutes,24JMD@186801|Clostridia	186801|Clostridia	N	Flagellar hook-length control protein	fliK	-	-	ko:K02414	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_hook
KFPFDFKC_01508	585394.RHOM_06965	1.14e-106	318.0	28H98@1|root,2Z7M1@2|Bacteria,1TRE9@1239|Firmicutes,24F21@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MgtE_N
KFPFDFKC_01509	585394.RHOM_06960	1.36e-59	188.0	COG2882@1|root,COG2882@2|Bacteria,1VK96@1239|Firmicutes,24RWK@186801|Clostridia	186801|Clostridia	NOU	flagellar export protein FliJ	fliJ	-	-	ko:K02413	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliJ
KFPFDFKC_01510	622312.ROSEINA2194_00945	4.32e-270	744.0	COG1157@1|root,COG1157@2|Bacteria,1TP0R@1239|Firmicutes,25E6B@186801|Clostridia	186801|Clostridia	NU	Flagellar protein export ATPase FliI	fliI	-	3.6.3.14	ko:K02412,ko:K03224	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko01000,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
KFPFDFKC_01511	585394.RHOM_06950	2.45e-52	178.0	COG1317@1|root,COG1317@2|Bacteria,1V7UQ@1239|Firmicutes	1239|Firmicutes	NU	Flagellar assembly protein FliH	-	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
KFPFDFKC_01512	585394.RHOM_06945	1.56e-213	593.0	COG1536@1|root,COG1536@2|Bacteria,1TP01@1239|Firmicutes,2480B@186801|Clostridia	186801|Clostridia	N	Flagellar motor switch protein flig	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
KFPFDFKC_01513	622312.ROSEINA2194_00942	1.77e-227	644.0	COG1766@1|root,COG1766@2|Bacteria,1TRK0@1239|Firmicutes,2498Q@186801|Clostridia	186801|Clostridia	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
KFPFDFKC_01514	622312.ROSEINA2194_00941	9.85e-41	137.0	COG1677@1|root,COG1677@2|Bacteria	2|Bacteria	N	Flagellar hook-basal body complex protein FliE	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
KFPFDFKC_01515	585394.RHOM_06925	1.29e-79	238.0	COG1558@1|root,COG1558@2|Bacteria,1V6NB@1239|Firmicutes,24JJW@186801|Clostridia	186801|Clostridia	N	Belongs to the flagella basal body rod proteins family	flgC	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
KFPFDFKC_01516	622312.ROSEINA2194_00939	3.78e-58	183.0	COG1815@1|root,COG1815@2|Bacteria,1VEUZ@1239|Firmicutes,24RBE@186801|Clostridia	186801|Clostridia	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	flgB	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
KFPFDFKC_01517	622312.ROSEINA2194_00938	8.66e-155	462.0	COG0550@1|root,COG4465@1|root,COG0550@2|Bacteria,COG4465@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
KFPFDFKC_01518	622312.ROSEINA2194_00938	0.0	1188.0	COG0550@1|root,COG4465@1|root,COG0550@2|Bacteria,COG4465@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
KFPFDFKC_01519	622312.ROSEINA2194_00937	1e-141	413.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia	186801|Clostridia	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
KFPFDFKC_01520	585394.RHOM_06900	1.93e-233	657.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia	186801|Clostridia	O	chelatase subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
KFPFDFKC_01521	622312.ROSEINA2194_00935	4.84e-95	282.0	COG1191@1|root,COG1191@2|Bacteria,1TPJ5@1239|Firmicutes,247XH@186801|Clostridia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigK	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
KFPFDFKC_01522	622312.ROSEINA2194_00934	1.54e-138	400.0	COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,249AH@186801|Clostridia	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD_2	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
KFPFDFKC_01523	585394.RHOM_06885	9.4e-100	294.0	2943S@1|root,2ZRIE@2|Bacteria,1V3J6@1239|Firmicutes,24HEP@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	KatE	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01524	585394.RHOM_06880	2.9e-252	715.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
KFPFDFKC_01525	585394.RHOM_06865	9.22e-46	149.0	2E3QR@1|root,32YNK@2|Bacteria,1VENX@1239|Firmicutes,24QVR@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
KFPFDFKC_01526	622312.ROSEINA2194_00929	0.0	890.0	COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,2484I@186801|Clostridia	186801|Clostridia	L	DNA helicase	yjcD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
KFPFDFKC_01527	585394.RHOM_06855	0.0	922.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
KFPFDFKC_01528	585394.RHOM_06850	1.55e-213	612.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
KFPFDFKC_01529	585394.RHOM_06845	1.78e-198	563.0	COG2182@1|root,COG2182@2|Bacteria,1VRPK@1239|Firmicutes,24Y63@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
KFPFDFKC_01531	622312.ROSEINA2194_00922	3.08e-33	117.0	2E34J@1|root,32Y4N@2|Bacteria,1VESM@1239|Firmicutes,24QZX@186801|Clostridia	186801|Clostridia	S	COG NOG18028 non supervised orthologous group	cotJB	-	-	ko:K06333	-	-	-	-	ko00000	-	-	-	CotJB
KFPFDFKC_01532	585394.RHOM_06825	6.37e-36	126.0	COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,247YJ@186801|Clostridia	186801|Clostridia	P	PFAM Manganese containing catalase	cotJC	-	-	ko:K06334	-	-	-	-	ko00000	-	-	-	Mn_catalase
KFPFDFKC_01533	610130.Closa_1386	6.81e-22	92.8	2BD7I@1|root,326VM@2|Bacteria,1USRN@1239|Firmicutes,25ASU@186801|Clostridia,223BK@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01534	610130.Closa_1385	5.04e-78	247.0	292DC@1|root,2ZPXP@2|Bacteria,1V4KX@1239|Firmicutes,24SZM@186801|Clostridia,2223F@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01535	397291.C804_01109	3.08e-37	142.0	COG3584@1|root,COG3772@1|root,COG3584@2|Bacteria,COG3772@2|Bacteria,1VG3D@1239|Firmicutes,25KGI@186801|Clostridia,27QPE@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Phage lysozyme	-	-	-	-	-	-	-	-	-	-	-	-	Phage_lysozyme
KFPFDFKC_01536	1235799.C818_04239	3.08e-34	124.0	2BXGE@1|root,305PQ@2|Bacteria,1V5V1@1239|Firmicutes,24IKM@186801|Clostridia	186801|Clostridia	S	Bacteriophage holin family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_1
KFPFDFKC_01542	1163671.JAGI01000002_gene2842	1.74e-33	125.0	2DP8K@1|root,3310Z@2|Bacteria,1UM2Y@1239|Firmicutes,25GVV@186801|Clostridia	186801|Clostridia	S	Uncharacterised protein conserved in bacteria (DUF2313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2313
KFPFDFKC_01543	1235790.C805_00607	1.64e-105	320.0	COG3299@1|root,COG3299@2|Bacteria,1TQZU@1239|Firmicutes,249WP@186801|Clostridia,25WIV@186806|Eubacteriaceae	186801|Clostridia	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
KFPFDFKC_01544	642492.Clole_2742	9.21e-41	139.0	COG3628@1|root,COG3628@2|Bacteria,1V9Z3@1239|Firmicutes,24MZA@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2634)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2634
KFPFDFKC_01545	357809.Cphy_0791	1.42e-17	78.6	2E4UZ@1|root,32ZPC@2|Bacteria,1VFDY@1239|Firmicutes,24R3J@186801|Clostridia,221H3@1506553|Lachnoclostridium	186801|Clostridia	S	Protein of unknown function (DUF2577)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2577
KFPFDFKC_01546	1029718.SFBM_0133	2.73e-130	380.0	COG4193@1|root,COG4193@2|Bacteria,1TYY9@1239|Firmicutes,248KE@186801|Clostridia,36FSI@31979|Clostridiaceae	186801|Clostridia	G	PFAM Phage late control gene D protein (GPD)	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,NLPC_P60,Peptidase_M23
KFPFDFKC_01547	742740.HMPREF9474_02343	5.96e-84	256.0	COG1652@1|root,COG1652@2|Bacteria,1V78C@1239|Firmicutes,24JMB@186801|Clostridia,2211Q@1506553|Lachnoclostridium	186801|Clostridia	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
KFPFDFKC_01548	742740.HMPREF9474_02344	1.88e-275	793.0	COG5281@1|root,COG5281@2|Bacteria,1TPWF@1239|Firmicutes,24A8R@186801|Clostridia,220JR@1506553|Lachnoclostridium	186801|Clostridia	S	tape measure	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
KFPFDFKC_01549	742740.HMPREF9474_02345	8.7e-72	218.0	2CIH9@1|root,31MHP@2|Bacteria,1V74S@1239|Firmicutes,24JK6@186801|Clostridia,221AV@1506553|Lachnoclostridium	186801|Clostridia	S	Phage XkdN-like tail assembly chaperone protein, TAC	-	-	-	-	-	-	-	-	-	-	-	-	Phage_TAC_5
KFPFDFKC_01550	1235790.C805_00599	6.52e-88	260.0	2CBAP@1|root,2ZCKJ@2|Bacteria,1V2H5@1239|Firmicutes,24FQW@186801|Clostridia,25YN6@186806|Eubacteriaceae	186801|Clostridia	S	Phage tail tube protein	xkdM	-	-	-	-	-	-	-	-	-	-	-	DUF2001
KFPFDFKC_01551	742740.HMPREF9474_02347	9.8e-234	652.0	28IGV@1|root,2Z8I6@2|Bacteria,1TP1Y@1239|Firmicutes,24AS0@186801|Clostridia,220YZ@1506553|Lachnoclostridium	186801|Clostridia	S	Phage tail sheath C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_sheath_1,Phage_sheath_1C,Phage_sheath_1N
KFPFDFKC_01553	742740.HMPREF9474_02349	8e-38	132.0	2E3R8@1|root,32YNZ@2|Bacteria,1VIVW@1239|Firmicutes,24SI8@186801|Clostridia,221GM@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01554	742740.HMPREF9474_02350	7.15e-73	223.0	2BT3Y@1|root,32N8H@2|Bacteria,1U4T1@1239|Firmicutes,25PZF@186801|Clostridia,221ES@1506553|Lachnoclostridium	186801|Clostridia	S	Bacteriophage HK97-gp10, putative tail-component	-	-	-	-	-	-	-	-	-	-	-	-	HK97-gp10_like
KFPFDFKC_01555	608534.GCWU000341_02290	1.69e-36	128.0	2E844@1|root,332HW@2|Bacteria,1VI21@1239|Firmicutes,24Q25@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01556	1123511.KB905868_gene180	9.27e-33	117.0	2DMP3@1|root,32ST4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_connect_1
KFPFDFKC_01557	610130.Closa_1395	4.35e-156	447.0	2BZ9Z@1|root,2Z97E@2|Bacteria,1U6NR@1239|Firmicutes,24FZN@186801|Clostridia,21XYR@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01558	1042156.CXIVA_00720	1.46e-62	201.0	2AY8I@1|root,31QAU@2|Bacteria,1U45W@1239|Firmicutes,24T5D@186801|Clostridia,36NSI@31979|Clostridiaceae	186801|Clostridia	S	Phage minor structural protein GP20	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GP20
KFPFDFKC_01560	742740.HMPREF9474_02356	5.54e-133	408.0	COG2369@1|root,COG2369@2|Bacteria,1U6KJ@1239|Firmicutes,24AM0@186801|Clostridia,220AG@1506553|Lachnoclostridium	186801|Clostridia	M	Phage head morphogenesis protein, SPP1 gp7 family	-	-	-	-	-	-	-	-	-	-	-	-	ADPrib_exo_Tox,Phage_Mu_F
KFPFDFKC_01561	1042156.CXIVA_01850	1.44e-222	628.0	2CEGT@1|root,2Z7ZB@2|Bacteria,1TP3Y@1239|Firmicutes,24CBJ@186801|Clostridia,36HMF@31979|Clostridiaceae	186801|Clostridia	S	Phage portal protein, SPP1 Gp6-like	-	-	-	-	-	-	-	-	-	-	-	-	Phage_prot_Gp6
KFPFDFKC_01562	33035.JPJF01000106_gene3130	1.03e-26	102.0	2BXU8@1|root,32YRQ@2|Bacteria,1VG7H@1239|Firmicutes,24SHP@186801|Clostridia,3Y20C@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01563	903814.ELI_3215	3.93e-234	653.0	COG1783@1|root,COG1783@2|Bacteria,1TT2C@1239|Firmicutes,24A7T@186801|Clostridia,25XPU@186806|Eubacteriaceae	186801|Clostridia	S	Phage terminase large subunit	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
KFPFDFKC_01564	411490.ANACAC_00784	1.19e-96	291.0	COG3728@1|root,COG3728@2|Bacteria,1V8HJ@1239|Firmicutes,25CWY@186801|Clostridia	186801|Clostridia	L	terminase, small subunit	xtmA	-	-	ko:K07474	-	-	-	-	ko00000	-	-	-	Phage_terminase,Sigma70_r4_2,Terminase_2
KFPFDFKC_01566	1235792.C808_05326	2.78e-55	176.0	2DS3B@1|root,33EBS@2|Bacteria,1VM4J@1239|Firmicutes,24N4N@186801|Clostridia,27QBE@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01569	1120971.AUCA01000043_gene1170	3.79e-207	587.0	COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4H9YP@91061|Bacilli,2791R@186823|Alicyclobacillaceae	91061|Bacilli	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
KFPFDFKC_01570	1121289.JHVL01000007_gene2771	8.65e-25	97.8	2E38J@1|root,32Y88@2|Bacteria,1VAXK@1239|Firmicutes,24N7K@186801|Clostridia,36S09@31979|Clostridiaceae	186801|Clostridia	S	VRR_NUC	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01571	1449126.JQKL01000051_gene3184	1.81e-313	885.0	COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,2495S@186801|Clostridia	186801|Clostridia	L	Virulence-associated protein E	-	-	-	-	-	-	-	-	-	-	-	-	VirE
KFPFDFKC_01572	86416.Clopa_0561	8.31e-266	751.0	COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,36EDD@31979|Clostridiaceae	186801|Clostridia	L	DNA polymerase	-	-	2.7.7.7	ko:K02334	-	-	-	-	ko00000,ko01000	-	-	-	DNA_pol_A,DNA_pol_A_exo1
KFPFDFKC_01573	86416.Clopa_0560	4.32e-72	228.0	28J2E@1|root,2Z8YX@2|Bacteria,1TRF9@1239|Firmicutes,249U3@186801|Clostridia,36EHP@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF2815)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2815
KFPFDFKC_01574	1120746.CCNL01000014_gene2086	8.13e-124	370.0	COG2887@1|root,COG2887@2|Bacteria	2|Bacteria	L	Belongs to the helicase family. UvrD subfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF2800
KFPFDFKC_01590	1235790.C805_00592	8.28e-36	129.0	COG1396@1|root,COG1396@2|Bacteria,1VQEA@1239|Firmicutes,24WD0@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
KFPFDFKC_01591	521003.COLINT_03302	9.43e-41	135.0	2BI4J@1|root,32C9R@2|Bacteria,2H10W@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01593	1235790.C805_00591	1.74e-61	193.0	COG2856@1|root,COG2856@2|Bacteria,1V4N6@1239|Firmicutes,24JDG@186801|Clostridia,25YTW@186806|Eubacteriaceae	186801|Clostridia	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
KFPFDFKC_01595	1235792.C808_03102	1.78e-95	294.0	COG4823@1|root,COG4823@2|Bacteria,1V38S@1239|Firmicutes,24G7Z@186801|Clostridia	186801|Clostridia	V	Abi-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
KFPFDFKC_01596	478749.BRYFOR_07230	4.99e-87	260.0	COG4636@1|root,COG4636@2|Bacteria,1V1QN@1239|Firmicutes,25DNV@186801|Clostridia	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
KFPFDFKC_01597	1256908.HMPREF0373_00206	2.62e-188	544.0	COG1961@1|root,COG1961@2|Bacteria,1TP0S@1239|Firmicutes,24A9P@186801|Clostridia,25WS8@186806|Eubacteriaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
KFPFDFKC_01598	585394.RHOM_06825	3.68e-92	273.0	COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,247YJ@186801|Clostridia	186801|Clostridia	P	PFAM Manganese containing catalase	cotJC	-	-	ko:K06334	-	-	-	-	ko00000	-	-	-	Mn_catalase
KFPFDFKC_01599	585394.RHOM_06810	1.1e-157	456.0	28KI7@1|root,2ZA3H@2|Bacteria,1V07J@1239|Firmicutes,24EVH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01600	622312.ROSEINA2194_00916	1.72e-71	228.0	2B4WY@1|root,31XPQ@2|Bacteria,1V739@1239|Firmicutes,24IHF@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01601	585394.RHOM_06800	6.37e-177	506.0	28MVQ@1|root,2ZB38@2|Bacteria,1UUTH@1239|Firmicutes,24AV8@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01602	585394.RHOM_06795	0.0	1228.0	2C1EE@1|root,2Z86R@2|Bacteria,1TS39@1239|Firmicutes,24ABS@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	Rnd	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01603	585394.RHOM_06790	8.58e-233	644.0	COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia	186801|Clostridia	E	PFAM Aminotransferase class I and II	hisC	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
KFPFDFKC_01604	622312.ROSEINA2194_01367	0.0	956.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
KFPFDFKC_01605	585394.RHOM_09335	4.86e-55	172.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia	186801|Clostridia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
KFPFDFKC_01606	585394.RHOM_09340	2.15e-183	520.0	COG1073@1|root,COG1073@2|Bacteria,1UF81@1239|Firmicutes,24BZ7@186801|Clostridia	186801|Clostridia	H	Protein of unknown function (DUF2974)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2974
KFPFDFKC_01607	622312.ROSEINA2194_01364	5.39e-111	327.0	COG0561@1|root,COG0561@2|Bacteria,1TSZZ@1239|Firmicutes,25B6T@186801|Clostridia	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
KFPFDFKC_01610	622312.ROSEINA2194_03155	6.02e-105	310.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
KFPFDFKC_01611	622312.ROSEINA2194_03156	7.17e-235	647.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
KFPFDFKC_01612	585394.RHOM_02890	1.75e-74	229.0	2CB94@1|root,32XMH@2|Bacteria,1VCD1@1239|Firmicutes,24MX5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01613	622312.ROSEINA2194_03158	9.83e-190	530.0	COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,248EQ@186801|Clostridia	186801|Clostridia	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
KFPFDFKC_01614	585394.RHOM_02880	1.53e-25	96.7	2EJD6@1|root,33D47@2|Bacteria,1VKED@1239|Firmicutes,24T7S@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01615	622312.ROSEINA2194_03159	7.09e-72	219.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
KFPFDFKC_01616	622312.ROSEINA2194_03160	1.82e-129	372.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia	186801|Clostridia	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
KFPFDFKC_01617	622312.ROSEINA2194_03161	9.27e-91	266.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia	186801|Clostridia	K	Hydrolase, P-loop family	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
KFPFDFKC_01618	622312.ROSEINA2194_03162	2.43e-65	204.0	2AZ5D@1|root,31RC2@2|Bacteria,1V74Z@1239|Firmicutes,24KGW@186801|Clostridia	186801|Clostridia	S	YcxB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
KFPFDFKC_01619	622312.ROSEINA2194_00823	1.01e-114	332.0	COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,24E4V@186801|Clostridia	186801|Clostridia	S	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins	ribU	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
KFPFDFKC_01620	622312.ROSEINA2194_00824	0.0	1248.0	COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,248P0@186801|Clostridia	186801|Clostridia	K	Tex-like protein N-terminal domain	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
KFPFDFKC_01621	585394.RHOM_02840	7.81e-34	120.0	2EGCD@1|root,33A46@2|Bacteria,1VMG3@1239|Firmicutes,24UKI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01622	585394.RHOM_02835	3.14e-43	146.0	2DNZJ@1|root,32ZX7@2|Bacteria,1VHMI@1239|Firmicutes,24SBG@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
KFPFDFKC_01623	585394.RHOM_02825	2.44e-75	236.0	COG5523@1|root,COG5523@2|Bacteria,1VB3B@1239|Firmicutes,24N6Q@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
KFPFDFKC_01624	585394.RHOM_02820	4.11e-296	813.0	COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,2485Z@186801|Clostridia	186801|Clostridia	F	permease	pyrP	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
KFPFDFKC_01625	585394.RHOM_02815	3.86e-79	244.0	COG4758@1|root,COG4758@2|Bacteria,1V7WJ@1239|Firmicutes,24A1Z@186801|Clostridia	186801|Clostridia	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
KFPFDFKC_01626	397291.C804_03441	9.42e-72	220.0	COG3279@1|root,COG3279@2|Bacteria,1VBF7@1239|Firmicutes,24G1R@186801|Clostridia,27MWM@186928|unclassified Lachnospiraceae	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
KFPFDFKC_01627	585394.RHOM_02805	8.84e-169	475.0	COG0489@1|root,COG0489@2|Bacteria,1TQ34@1239|Firmicutes,24817@186801|Clostridia	186801|Clostridia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	-	-	-	-	-	-	-	-	-	ParA
KFPFDFKC_01628	585394.RHOM_02800	1.47e-214	598.0	COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,249C5@186801|Clostridia	186801|Clostridia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
KFPFDFKC_01630	1469948.JPNB01000002_gene3250	1.76e-199	562.0	COG1680@1|root,COG1680@2|Bacteria,1UC2C@1239|Firmicutes,24B3Q@186801|Clostridia,36FP4@31979|Clostridiaceae	186801|Clostridia	V	beta-lactamase	-	-	3.4.16.4	ko:K21469	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Beta-lactamase
KFPFDFKC_01631	1280694.AUJQ01000011_gene1768	5.24e-132	390.0	COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,249VN@186801|Clostridia,3NGIB@46205|Pseudobutyrivibrio	186801|Clostridia	J	tRNA synthetases class II (A)	alaXL	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
KFPFDFKC_01632	622312.ROSEINA2194_02126	4.16e-43	145.0	2FC79@1|root,344B3@2|Bacteria,1W1AZ@1239|Firmicutes,24W3X@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01633	622312.ROSEINA2194_02447	5.9e-18	83.2	COG2768@1|root,COG2768@2|Bacteria,1TQAW@1239|Firmicutes,247IS@186801|Clostridia	186801|Clostridia	C	binding domain protein	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4,Fer4_21,Fer4_6,Fer4_7
KFPFDFKC_01634	622312.ROSEINA2194_01738	2.51e-173	485.0	COG0703@1|root,COG1605@1|root,COG0703@2|Bacteria,COG1605@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,SKI
KFPFDFKC_01635	622312.ROSEINA2194_01737	2.99e-185	522.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,248MN@186801|Clostridia	186801|Clostridia	G	COG COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	siaP	-	-	ko:K21395	-	-	-	-	ko00000,ko02000	2.A.56.1	-	-	DctP
KFPFDFKC_01636	622312.ROSEINA2194_01736	1.14e-255	707.0	COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
KFPFDFKC_01637	622312.ROSEINA2194_01735	1.34e-97	289.0	COG3090@1|root,COG3090@2|Bacteria,1V3PZ@1239|Firmicutes,24HA7@186801|Clostridia	186801|Clostridia	G	COG COG3090 TRAP-type C4-dicarboxylate transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
KFPFDFKC_01638	1408312.JNJS01000001_gene1438	6.75e-139	397.0	COG0710@1|root,COG0710@2|Bacteria,1TSPN@1239|Firmicutes,249EX@186801|Clostridia,3NH3M@46205|Pseudobutyrivibrio	186801|Clostridia	E	Type I 3-dehydroquinase	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,SKI
KFPFDFKC_01639	622312.ROSEINA2194_01731	1.43e-259	715.0	COG0477@1|root,COG0477@2|Bacteria,1TS50@1239|Firmicutes,24BE2@186801|Clostridia	186801|Clostridia	EGP	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
KFPFDFKC_01640	622312.ROSEINA2194_01730	2.24e-204	566.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
KFPFDFKC_01641	622312.ROSEINA2194_01729	4.99e-179	502.0	COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,24B1W@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
KFPFDFKC_01642	622312.ROSEINA2194_01728	1.24e-127	370.0	COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,24B1W@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
KFPFDFKC_01643	622312.ROSEINA2194_01725	0.0	1284.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia	186801|Clostridia	C	NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
KFPFDFKC_01644	622312.ROSEINA2194_01722	7.94e-207	572.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
KFPFDFKC_01645	411470.RUMGNA_03147	8.65e-64	198.0	COG0454@1|root,COG0456@2|Bacteria,1VDD6@1239|Firmicutes,24NEN@186801|Clostridia,3Y0NK@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
KFPFDFKC_01646	622312.ROSEINA2194_00591	0.0	1211.0	COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia	186801|Clostridia	S	Myosin-crossreactive antigen	-	-	4.2.1.53	ko:K10254	-	-	-	-	ko00000,ko01000	-	-	-	MCRA
KFPFDFKC_01647	1235800.C819_03126	2.51e-99	291.0	COG1309@1|root,COG1309@2|Bacteria,1UYIP@1239|Firmicutes,249K5@186801|Clostridia,27TME@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Transcriptional regulator C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
KFPFDFKC_01648	33035.JPJF01000032_gene2180	0.0	949.0	COG3534@1|root,COG3534@2|Bacteria,1TRY9@1239|Firmicutes,2497J@186801|Clostridia,3Y1AY@572511|Blautia	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminus	abfA	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
KFPFDFKC_01649	33035.JPJF01000032_gene2181	3.15e-165	466.0	COG0395@1|root,COG0395@2|Bacteria,1TT5G@1239|Firmicutes,249MU@186801|Clostridia,3Y17N@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17236	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	BPD_transp_1
KFPFDFKC_01650	33035.JPJF01000032_gene2182	2.43e-188	526.0	COG1175@1|root,COG1175@2|Bacteria,1TRSP@1239|Firmicutes,24906@186801|Clostridia,3Y17F@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17235	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	BPD_transp_1
KFPFDFKC_01651	33035.JPJF01000032_gene2183	3.93e-269	744.0	COG1653@1|root,COG1653@2|Bacteria,1TS9Z@1239|Firmicutes,2490T@186801|Clostridia	186801|Clostridia	G	Extracellular solute-binding protein	araN	-	-	ko:K17234	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	SBP_bac_1,SBP_bac_8
KFPFDFKC_01652	33035.JPJF01000032_gene2184	0.0	971.0	COG3533@1|root,COG3533@2|Bacteria,1TNYA@1239|Firmicutes,24841@186801|Clostridia,3Y0XI@572511|Blautia	186801|Clostridia	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
KFPFDFKC_01653	33035.JPJF01000032_gene2185	4.82e-178	504.0	COG1609@1|root,COG1609@2|Bacteria,1TRWK@1239|Firmicutes,24DAV@186801|Clostridia	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
KFPFDFKC_01654	622312.ROSEINA2194_02127	3.56e-176	501.0	COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,248FR@186801|Clostridia	186801|Clostridia	M	Monogalactosyldiacylglycerol synthase	-	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glycos_transf_1,MGDG_synth
KFPFDFKC_01655	622312.ROSEINA2194_02128	2.8e-76	234.0	COG0344@1|root,COG0344@2|Bacteria,1V798@1239|Firmicutes,24KR2@186801|Clostridia	186801|Clostridia	I	Belongs to the PlsY family	-	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
KFPFDFKC_01656	585394.RHOM_13085	2.97e-211	583.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia	186801|Clostridia	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
KFPFDFKC_01657	585394.RHOM_13095	4.32e-80	239.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,24JB0@186801|Clostridia	186801|Clostridia	S	YqeY-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
KFPFDFKC_01658	585394.RHOM_13100	9.68e-107	330.0	COG0791@1|root,COG3883@1|root,COG0791@2|Bacteria,COG3883@2|Bacteria,1UVYK@1239|Firmicutes,249G6@186801|Clostridia	186801|Clostridia	M	NlpC p60 family	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
KFPFDFKC_01659	585394.RHOM_13110	1.42e-227	644.0	COG1388@1|root,COG1388@2|Bacteria,1TSVC@1239|Firmicutes,248VQ@186801|Clostridia	186801|Clostridia	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794,LysM
KFPFDFKC_01660	585394.RHOM_13115	1.26e-46	150.0	COG4466@1|root,COG4466@2|Bacteria	2|Bacteria	S	Protein conserved in bacteria	veg	-	-	-	-	-	-	-	-	-	-	-	VEG
KFPFDFKC_01661	585394.RHOM_13120	2.53e-53	171.0	2DD3J@1|root,32U0T@2|Bacteria,1VB00@1239|Firmicutes,24N49@186801|Clostridia	186801|Clostridia	S	PrcB C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PrcB_C
KFPFDFKC_01662	585394.RHOM_13125	1.6e-146	416.0	COG0204@1|root,COG0204@2|Bacteria,1UMJA@1239|Firmicutes,249AV@186801|Clostridia	186801|Clostridia	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	plsC_1	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
KFPFDFKC_01663	622312.ROSEINA2194_02141	1.55e-254	708.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
KFPFDFKC_01664	622312.ROSEINA2194_02142	4.12e-207	578.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
KFPFDFKC_01666	622312.ROSEINA2194_03042	1.71e-143	412.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,247ST@186801|Clostridia	186801|Clostridia	T	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
KFPFDFKC_01667	585394.RHOM_02215	1.32e-107	311.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
KFPFDFKC_01669	622312.ROSEINA2194_02147	6.06e-135	388.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,247NA@186801|Clostridia	186801|Clostridia	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
KFPFDFKC_01670	585394.RHOM_02190	0.0	1407.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia	186801|Clostridia	C	Glycine radical	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
KFPFDFKC_01671	585394.RHOM_02185	5.04e-101	305.0	COG2199@1|root,COG2199@2|Bacteria,1UV0N@1239|Firmicutes,24NW2@186801|Clostridia	186801|Clostridia	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3
KFPFDFKC_01672	411902.CLOBOL_04339	0.0	1267.0	COG0480@1|root,COG0480@2|Bacteria,1TPQH@1239|Firmicutes,247X4@186801|Clostridia,21XWM@1506553|Lachnoclostridium	186801|Clostridia	J	COG COG0480 Translation elongation factors (GTPases)	-	-	-	ko:K18220	-	-	-	-	br01600,ko00000,ko01504	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
KFPFDFKC_01673	1232453.BAIF02000006_gene1455	5.62e-274	751.0	COG0738@1|root,COG0738@2|Bacteria,1UP7G@1239|Firmicutes,25H7V@186801|Clostridia	186801|Clostridia	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
KFPFDFKC_01674	1121864.OMO_01639	6.96e-116	332.0	COG1191@1|root,COG1191@2|Bacteria,1V1GF@1239|Firmicutes	1239|Firmicutes	K	Psort location Cytoplasmic, score	XK26_06155	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4
KFPFDFKC_01675	1121864.OMO_01638	7.15e-95	276.0	COG1595@1|root,COG1595@2|Bacteria,1UYSW@1239|Firmicutes	1239|Firmicutes	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	-
KFPFDFKC_01676	1232452.BAIB02000011_gene2185	4.37e-32	111.0	2EF0F@1|root,338TI@2|Bacteria,1VHS7@1239|Firmicutes,24TZ5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01677	1121864.OMO_01636	1.29e-134	388.0	COG0468@1|root,COG0468@2|Bacteria,1V9SB@1239|Firmicutes	1239|Firmicutes	L	Psort location Cytoplasmic, score 8.87	XK27_03350	-	-	-	-	-	-	-	-	-	-	-	AAA_25
KFPFDFKC_01678	1226325.HMPREF1548_06048	4.04e-52	164.0	2AJW5@1|root,31AIZ@2|Bacteria,1V7QN@1239|Firmicutes,24JQH@186801|Clostridia,36PDP@31979|Clostridiaceae	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
KFPFDFKC_01679	1226322.HMPREF1545_02568	6.52e-93	272.0	COG1595@1|root,COG1595@2|Bacteria,1TSMC@1239|Firmicutes,25FSS@186801|Clostridia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
KFPFDFKC_01680	1226322.HMPREF1545_02567	8.78e-238	653.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,2N6PD@216572|Oscillospiraceae	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	-	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
KFPFDFKC_01681	1226322.HMPREF1545_02565	8.25e-79	234.0	COG1396@1|root,COG1396@2|Bacteria,1V50Y@1239|Firmicutes,25BHS@186801|Clostridia,2N8I8@216572|Oscillospiraceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
KFPFDFKC_01682	1226322.HMPREF1545_02564	8.04e-70	211.0	296J0@1|root,2ZTUJ@2|Bacteria,1V3IP@1239|Firmicutes,24H9K@186801|Clostridia,2N8QM@216572|Oscillospiraceae	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
KFPFDFKC_01683	1121864.OMO_01631	0.0	929.0	COG1961@1|root,COG1961@2|Bacteria,1TP0S@1239|Firmicutes,4HBBX@91061|Bacilli,4B6EH@81852|Enterococcaceae	91061|Bacilli	L	Domain of unknown function (DUF4368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
KFPFDFKC_01684	1235790.C805_00151	9.09e-59	185.0	COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,24ARG@186801|Clostridia,25UV0@186806|Eubacteriaceae	186801|Clostridia	S	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	-	-	-	-	-	-	-	-	-	Macro
KFPFDFKC_01685	1235790.C805_00152	2.38e-76	229.0	2EYGQ@1|root,2ZJEI@2|Bacteria,1V2N3@1239|Firmicutes,24FXR@186801|Clostridia,25Y23@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial RNA polymerase, alpha chain C terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_A_CTD
KFPFDFKC_01687	515620.EUBELI_01663	6.47e-35	120.0	COG1476@1|root,COG1476@2|Bacteria,1VCCB@1239|Firmicutes,25BIG@186801|Clostridia,25X3K@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulators	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
KFPFDFKC_01688	411463.EUBVEN_02570	3.13e-169	473.0	COG2932@1|root,COG2932@2|Bacteria,1TQWX@1239|Firmicutes,24CWA@186801|Clostridia,25VQA@186806|Eubacteriaceae	186801|Clostridia	K	Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,Peptidase_S24
KFPFDFKC_01689	1235790.C805_00164	1.58e-301	822.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,25V11@186806|Eubacteriaceae	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
KFPFDFKC_01690	1235800.C819_02144	1.53e-47	152.0	COG1974@1|root,COG1974@2|Bacteria,1UGUB@1239|Firmicutes,25PEE@186801|Clostridia,27SN4@186928|unclassified Lachnospiraceae	186801|Clostridia	KT	LexA DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LexA_DNA_bind
KFPFDFKC_01691	500632.CLONEX_00611	7e-54	168.0	2E5HW@1|root,33098@2|Bacteria,1VFFD@1239|Firmicutes,24QMD@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01692	742765.HMPREF9457_03459	6.67e-43	139.0	2EK2I@1|root,33DSZ@2|Bacteria,1VM2R@1239|Firmicutes,24SH4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01693	742765.HMPREF9457_03460	1.78e-69	210.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	HTH_3,HTH_31,Sigma70_r2,Sigma70_r4_2
KFPFDFKC_01694	483218.BACPEC_00245	1.81e-54	173.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
KFPFDFKC_01696	483218.BACPEC_00247	2.02e-48	157.0	COG1476@1|root,COG1476@2|Bacteria,1VK4C@1239|Firmicutes,24WH5@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
KFPFDFKC_01697	483218.BACPEC_00248	7.96e-84	249.0	COG1961@1|root,COG1961@2|Bacteria,1VHBZ@1239|Firmicutes,25FRU@186801|Clostridia	186801|Clostridia	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01698	483218.BACPEC_00249	4e-60	187.0	COG2337@1|root,COG2337@2|Bacteria,1VHCF@1239|Firmicutes,24RYC@186801|Clostridia	186801|Clostridia	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PemK_toxin
KFPFDFKC_01699	483218.BACPEC_00250	2.49e-31	111.0	2CCB2@1|root,32S7G@2|Bacteria,1VABI@1239|Firmicutes,24KT1@186801|Clostridia,26CGQ@186813|unclassified Clostridiales	186801|Clostridia	S	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
KFPFDFKC_01700	397290.C810_01285	2.6e-227	633.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,27IJX@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_integrase
KFPFDFKC_01701	585394.RHOM_10085	5.84e-89	264.0	COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,24MMZ@186801|Clostridia	186801|Clostridia	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	yfkJ	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
KFPFDFKC_01702	1469948.JPNB01000002_gene3758	6.4e-284	867.0	COG0366@1|root,COG0366@2|Bacteria,1UIVZ@1239|Firmicutes,25GG5@186801|Clostridia,36VA5@31979|Clostridiaceae	186801|Clostridia	GN	Bacterial pullanase-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,Alpha-amylase,PUD
KFPFDFKC_01703	622312.ROSEINA2194_00796	4.85e-296	810.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,248XN@186801|Clostridia	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12,6.1.1.23	ko:K01876,ko:K09759	ko00970,map00970	M00359,M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_2,tRNA_anti-codon
KFPFDFKC_01704	585394.RHOM_10070	6.76e-130	379.0	COG0721@1|root,COG1670@1|root,COG0721@2|Bacteria,COG1670@2|Bacteria,1V6E0@1239|Firmicutes,24G2M@186801|Clostridia	186801|Clostridia	J	acetyltransferase, GNAT family	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
KFPFDFKC_01705	622312.ROSEINA2194_00798	1.46e-314	861.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
KFPFDFKC_01706	585394.RHOM_10060	1.4e-314	860.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
KFPFDFKC_01707	585394.RHOM_04845	8.71e-64	200.0	COG1418@1|root,COG1418@2|Bacteria,1V4QX@1239|Firmicutes,24JBS@186801|Clostridia	186801|Clostridia	S	HD superfamily hydrolase	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
KFPFDFKC_01708	585394.RHOM_04850	0.0	1156.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
KFPFDFKC_01709	585394.RHOM_04855	0.0	986.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia	186801|Clostridia	V	Abc transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
KFPFDFKC_01710	585394.RHOM_04860	2.13e-61	194.0	COG1846@1|root,COG1846@2|Bacteria,1VEYN@1239|Firmicutes,24S21@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
KFPFDFKC_01711	585394.RHOM_04865	0.0	1309.0	COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia	186801|Clostridia	F	Ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
KFPFDFKC_01712	1121296.JONJ01000004_gene974	1.85e-50	163.0	COG5496@1|root,COG5496@2|Bacteria,1VAZJ@1239|Firmicutes,24MWR@186801|Clostridia,222ZV@1506553|Lachnoclostridium	186801|Clostridia	S	Thioesterase superfamily	-	-	3.1.2.29	ko:K18700	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
KFPFDFKC_01713	357809.Cphy_0713	9.01e-137	392.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,21Y17@1506553|Lachnoclostridium	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
KFPFDFKC_01714	585394.RHOM_05995	3.28e-61	189.0	2F3F9@1|root,33W92@2|Bacteria,1VVFD@1239|Firmicutes,25130@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01715	585394.RHOM_06000	7.1e-82	253.0	COG1434@1|root,COG1434@2|Bacteria,1VA42@1239|Firmicutes,24HKK@186801|Clostridia	186801|Clostridia	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
KFPFDFKC_01716	622312.ROSEINA2194_01565	4.22e-97	288.0	COG0328@1|root,COG3341@1|root,COG0328@2|Bacteria,COG3341@2|Bacteria,1V442@1239|Firmicutes,24HSE@186801|Clostridia	186801|Clostridia	L	Ribonuclease HI	rnhA	-	3.1.26.4	ko:K03469,ko:K06993	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,RNase_H
KFPFDFKC_01717	585394.RHOM_06010	1.85e-197	555.0	COG1609@1|root,COG1609@2|Bacteria,1TP9Q@1239|Firmicutes,24ARJ@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	araR	-	-	ko:K02103	-	-	-	-	ko00000,ko03000	-	-	-	GntR,Peripla_BP_3
KFPFDFKC_01718	622312.ROSEINA2194_02626	2.46e-85	255.0	COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,24HIJ@186801|Clostridia	186801|Clostridia	O	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	nrdG	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
KFPFDFKC_01720	585394.RHOM_04880	1.21e-114	346.0	COG0727@1|root,COG0727@2|Bacteria,1TSB6@1239|Firmicutes,24AQ9@186801|Clostridia	186801|Clostridia	S	N-methylation of lysine residues in flagellin K00599	-	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	CxxCxxCC
KFPFDFKC_01722	585394.RHOM_04900	1.13e-104	309.0	COG5632@1|root,COG5632@2|Bacteria,1V3JT@1239|Firmicutes,24D7K@186801|Clostridia	186801|Clostridia	M	n-acetylmuramoyl-l-alanine amidase	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2
KFPFDFKC_01723	585394.RHOM_04905	2.04e-191	550.0	COG0116@1|root,COG0116@2|Bacteria,1TT5F@1239|Firmicutes,249VY@186801|Clostridia	186801|Clostridia	L	Putative RNA methylase family UPF0020	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,UPF0020
KFPFDFKC_01724	585394.RHOM_04910	0.0	1225.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
KFPFDFKC_01727	585394.RHOM_01040	2.85e-193	541.0	COG0317@1|root,COG0317@2|Bacteria,1TQW3@1239|Firmicutes,2483C@186801|Clostridia	186801|Clostridia	KT	PFAM Region found in RelA SpoT proteins	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
KFPFDFKC_01728	585394.RHOM_04925	4.15e-216	599.0	COG0232@1|root,COG0232@2|Bacteria,1TPEI@1239|Firmicutes,247Q1@186801|Clostridia	186801|Clostridia	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
KFPFDFKC_01729	622312.ROSEINA2194_03431	0.0	934.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
KFPFDFKC_01730	585394.RHOM_04935	2.13e-238	661.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
KFPFDFKC_01731	585394.RHOM_04940	7.36e-95	285.0	COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,24BJI@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	trmK	-	2.1.1.217	ko:K06967	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_18,TrmK
KFPFDFKC_01732	585394.RHOM_04945	0.0	894.0	COG0441@1|root,COG0572@1|root,COG0441@2|Bacteria,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,249IT@186801|Clostridia	186801|Clostridia	F	uridine kinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
KFPFDFKC_01733	622312.ROSEINA2194_03540	1.41e-54	174.0	COG4416@1|root,COG4416@2|Bacteria,1VEMD@1239|Firmicutes,24MRR@186801|Clostridia	186801|Clostridia	S	COG NOG18757 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01734	622312.ROSEINA2194_03539	2.9e-167	472.0	2CC4I@1|root,2Z8PZ@2|Bacteria,1TQTT@1239|Firmicutes,24AJ3@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01735	622312.ROSEINA2194_03538	2.51e-119	344.0	COG0484@1|root,COG0484@2|Bacteria,1V1GK@1239|Firmicutes,2494E@186801|Clostridia	186801|Clostridia	O	DnaJ domain protein	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,TPR_2
KFPFDFKC_01736	585394.RHOM_10050	5.15e-90	265.0	COG1781@1|root,COG1781@2|Bacteria,1V6U9@1239|Firmicutes,24JJU@186801|Clostridia	186801|Clostridia	F	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
KFPFDFKC_01737	585394.RHOM_10045	3.83e-200	556.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N,PyrI_C
KFPFDFKC_01738	585394.RHOM_10035	2.14e-65	201.0	COG4905@1|root,COG4905@2|Bacteria,1VAQJ@1239|Firmicutes,24K5I@186801|Clostridia	186801|Clostridia	S	Putative ABC-transporter type IV	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
KFPFDFKC_01739	411460.RUMTOR_00907	3.04e-44	144.0	arCOG05874@1|root,2ZJ01@2|Bacteria,1VARV@1239|Firmicutes,24NY6@186801|Clostridia,3Y0H2@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01743	585394.RHOM_13865	7.64e-256	730.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
KFPFDFKC_01745	871963.Desdi_0542	9.47e-149	434.0	COG2826@1|root,COG2826@2|Bacteria,1TQ0G@1239|Firmicutes,248WB@186801|Clostridia,266TW@186807|Peptococcaceae	186801|Clostridia	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
KFPFDFKC_01746	665956.HMPREF1032_00008	7.34e-173	495.0	COG1196@1|root,COG1196@2|Bacteria,1TPU3@1239|Firmicutes,248HY@186801|Clostridia,3WIAK@541000|Ruminococcaceae	186801|Clostridia	D	MobA MobL family protein	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
KFPFDFKC_01748	1232453.BAIF02000019_gene3937	8.88e-41	134.0	2DRW8@1|root,32URU@2|Bacteria,1VA9A@1239|Firmicutes,24QD5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01749	657322.FPR_24010	8.88e-233	651.0	COG3378@1|root,COG3378@2|Bacteria,1TSGZ@1239|Firmicutes,24CI8@186801|Clostridia,3WHNR@541000|Ruminococcaceae	186801|Clostridia	S	Phage plasmid primase, P4 family	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	D5_N,Pox_D5
KFPFDFKC_01750	552396.HMPREF0863_00484	2.18e-89	268.0	COG0358@1|root,COG0358@2|Bacteria,1V0WR@1239|Firmicutes	1239|Firmicutes	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHC2
KFPFDFKC_01751	665956.HMPREF1032_01699	6.01e-127	376.0	28ICW@1|root,2Z8F5@2|Bacteria,1TSMN@1239|Firmicutes,24BRU@186801|Clostridia,3WJHI@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01752	903814.ELI_1145	1.01e-98	301.0	COG1191@1|root,COG1191@2|Bacteria,1U0Q7@1239|Firmicutes,249NN@186801|Clostridia,25VKH@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01753	1256908.HMPREF0373_00975	2.9e-22	98.2	COG1191@1|root,COG1191@2|Bacteria,1U0Q7@1239|Firmicutes,249NN@186801|Clostridia,25VKH@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01754	622312.ROSEINA2194_01535	4.09e-290	795.0	COG3290@1|root,COG3290@2|Bacteria,1UY02@1239|Firmicutes,24BV9@186801|Clostridia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
KFPFDFKC_01755	622312.ROSEINA2194_01534	2.37e-162	455.0	COG3279@1|root,COG3279@2|Bacteria,1VA5A@1239|Firmicutes,24DB9@186801|Clostridia	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
KFPFDFKC_01756	622312.ROSEINA2194_01533	1.2e-78	234.0	COG3279@1|root,COG3279@2|Bacteria,1VAGQ@1239|Firmicutes,24Q19@186801|Clostridia	186801|Clostridia	KT	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
KFPFDFKC_01757	622312.ROSEINA2194_01532	0.0	1272.0	2CF3Z@1|root,2Z97A@2|Bacteria,1UQMP@1239|Firmicutes,248YE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01758	717605.Theco_0700	0.000561	45.8	COG1309@1|root,COG1309@2|Bacteria,1UYXX@1239|Firmicutes,4HH8M@91061|Bacilli,26Y0V@186822|Paenibacillaceae	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
KFPFDFKC_01759	633147.Olsu_0240	3.1e-205	580.0	COG5361@1|root,COG5361@2|Bacteria,2GRDZ@201174|Actinobacteria,4CX4F@84998|Coriobacteriia	84998|Coriobacteriia	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
KFPFDFKC_01760	903814.ELI_2151	6.17e-288	809.0	COG2015@1|root,COG2015@2|Bacteria,1TR7Q@1239|Firmicutes,248SN@186801|Clostridia,25Y8G@186806|Eubacteriaceae	186801|Clostridia	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
KFPFDFKC_01761	1235802.C823_05093	9.92e-64	201.0	COG1595@1|root,COG1595@2|Bacteria,1V6SV@1239|Firmicutes,24HPR@186801|Clostridia,25X89@186806|Eubacteriaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ECF,Sigma70_r2,Sigma70_r4,Sigma70_r4_2
KFPFDFKC_01762	1123075.AUDP01000020_gene1495	2.48e-120	383.0	COG1948@1|root,COG4880@2|Bacteria,1TQK0@1239|Firmicutes,247VC@186801|Clostridia,3WIWG@541000|Ruminococcaceae	186801|Clostridia	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel,Cu_amine_oxidN1
KFPFDFKC_01764	632245.CLP_0713	8.73e-133	383.0	COG0657@1|root,COG0657@2|Bacteria,1TP1H@1239|Firmicutes,24D7F@186801|Clostridia,36E3F@31979|Clostridiaceae	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
KFPFDFKC_01765	622312.ROSEINA2194_02236	1.79e-287	786.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
KFPFDFKC_01767	622312.ROSEINA2194_02923	9.12e-69	212.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
KFPFDFKC_01768	1235793.C809_01302	1.74e-126	383.0	2BP58@1|root,32HW3@2|Bacteria,1V8J8@1239|Firmicutes,24HB1@186801|Clostridia,27PAY@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4367
KFPFDFKC_01769	585394.RHOM_00275	1.76e-153	436.0	COG0561@1|root,COG0561@2|Bacteria,1UFDJ@1239|Firmicutes,25B6S@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
KFPFDFKC_01771	411459.RUMOBE_02700	8.28e-95	280.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HU5@186801|Clostridia,3Y18Q@572511|Blautia	186801|Clostridia	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
KFPFDFKC_01772	411459.RUMOBE_02699	2.02e-219	607.0	COG0502@1|root,COG0502@2|Bacteria,1TPQ4@1239|Firmicutes,248J4@186801|Clostridia,3XYUJ@572511|Blautia	186801|Clostridia	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
KFPFDFKC_01773	411459.RUMOBE_02698	2.5e-129	371.0	COG0132@1|root,COG0132@2|Bacteria,1UYA3@1239|Firmicutes,24F15@186801|Clostridia,3Y0X3@572511|Blautia	186801|Clostridia	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
KFPFDFKC_01774	411459.RUMOBE_02697	1.8e-269	739.0	COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,25E7B@186801|Clostridia,3Y0YH@572511|Blautia	186801|Clostridia	H	Aminotransferase class-III	bioA	-	2.6.1.113,2.6.1.55,2.6.1.62,2.6.1.77	ko:K00833,ko:K03851,ko:K12256,ko:K15372	ko00330,ko00410,ko00430,ko00780,ko01100,map00330,map00410,map00430,map00780,map01100	M00123,M00573,M00577	R00908,R01684,R03231,R05652,R08714	RC00006,RC00008,RC00062,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
KFPFDFKC_01775	1408323.JQKK01000024_gene1322	1.28e-09	55.8	2DQE4@1|root,3368Z@2|Bacteria,1VJUF@1239|Firmicutes,24UJT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01776	585394.RHOM_00305	0.0	1201.0	COG0674@1|root,COG1013@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia	186801|Clostridia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K00169,ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N,TPP_enzyme_C
KFPFDFKC_01777	585394.RHOM_00310	4.46e-197	553.0	COG1014@1|root,COG1144@1|root,COG1014@2|Bacteria,COG1144@2|Bacteria,1TRFJ@1239|Firmicutes,24A29@186801|Clostridia	186801|Clostridia	C	oxidoreductase gamma subunit	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,POR
KFPFDFKC_01778	203119.Cthe_3129	7.14e-140	409.0	COG1055@1|root,COG1055@2|Bacteria,1TQCH@1239|Firmicutes,25CD7@186801|Clostridia,3WGPH@541000|Ruminococcaceae	186801|Clostridia	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
KFPFDFKC_01779	585394.RHOM_00325	1.23e-129	377.0	COG0697@1|root,COG0697@2|Bacteria,1V1H0@1239|Firmicutes,24BBW@186801|Clostridia	186801|Clostridia	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
KFPFDFKC_01780	515620.EUBELI_01774	3.94e-16	78.2	COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia,25VZP@186806|Eubacteriaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
KFPFDFKC_01781	411463.EUBVEN_01846	4.16e-30	107.0	COG3655@1|root,COG3655@2|Bacteria,1VEM0@1239|Firmicutes,24QPN@186801|Clostridia,25XUQ@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
KFPFDFKC_01782	411463.EUBVEN_01845	4.88e-77	232.0	COG3727@1|root,COG3727@2|Bacteria,1V3S8@1239|Firmicutes,24MYE@186801|Clostridia,25WIB@186806|Eubacteriaceae	186801|Clostridia	L	DNA mismatch endonuclease Vsr	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DUF559,Vsr
KFPFDFKC_01783	411463.EUBVEN_01844	1.03e-215	599.0	COG0270@1|root,COG0270@2|Bacteria,1TS3G@1239|Firmicutes,249Q9@186801|Clostridia,25VMQ@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	dcm	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
KFPFDFKC_01784	411463.EUBVEN_01843	3.2e-122	363.0	28HT5@1|root,2Z803@2|Bacteria,1UZTS@1239|Firmicutes,249EG@186801|Clostridia,25UZU@186806|Eubacteriaceae	186801|Clostridia	L	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RE_HpaII
KFPFDFKC_01785	1345695.CLSA_c09440	5.39e-164	488.0	COG1106@1|root,COG1106@2|Bacteria,1TQ9J@1239|Firmicutes,24C9X@186801|Clostridia	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
KFPFDFKC_01786	622312.ROSEINA2194_04392	7.93e-45	156.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
KFPFDFKC_01787	585394.RHOM_00370	1.17e-107	316.0	COG2357@1|root,COG2357@2|Bacteria,1VDTE@1239|Firmicutes,24Q2S@186801|Clostridia	186801|Clostridia	S	RelA SpoT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
KFPFDFKC_01788	622312.ROSEINA2194_04395	4.22e-143	414.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia	186801|Clostridia	P	phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
KFPFDFKC_01789	622312.ROSEINA2194_04397	8.2e-160	452.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia	186801|Clostridia	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
KFPFDFKC_01790	622312.ROSEINA2194_04398	8.63e-158	448.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,248C4@186801|Clostridia	186801|Clostridia	P	phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
KFPFDFKC_01791	622312.ROSEINA2194_04399	1.05e-170	477.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
KFPFDFKC_01792	585394.RHOM_00395	3.7e-116	337.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,24FTM@186801|Clostridia	186801|Clostridia	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
KFPFDFKC_01793	585394.RHOM_00400	0.0	901.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia	186801|Clostridia	P	Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
KFPFDFKC_01794	585394.RHOM_00405	2.98e-127	365.0	COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,24D6A@186801|Clostridia	186801|Clostridia	T	Response regulator receiver domain protein	phoB	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
KFPFDFKC_01795	585394.RHOM_00410	8.64e-215	604.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
KFPFDFKC_01796	585394.RHOM_00425	0.0	1634.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia	186801|Clostridia	L	snf2 family	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
KFPFDFKC_01797	585394.RHOM_00435	4.15e-103	301.0	COG1971@1|root,COG1971@2|Bacteria,1V4QK@1239|Firmicutes,24FY0@186801|Clostridia	186801|Clostridia	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
KFPFDFKC_01798	585394.RHOM_00440	3.24e-150	431.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia	186801|Clostridia	P	K -dependent Na Ca exchanger family protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
KFPFDFKC_01799	398512.JQKC01000037_gene4526	5.53e-06	55.1	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Cohesin,PPC,Peptidase_S8
KFPFDFKC_01800	585394.RHOM_15635	2.69e-29	108.0	2BAQE@1|root,32NWD@2|Bacteria,1V8VM@1239|Firmicutes,24WJV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01802	411459.RUMOBE_03440	6.45e-64	211.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,3XZC3@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 10.00	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
KFPFDFKC_01804	397291.C804_02972	7.9e-68	209.0	28I1B@1|root,30E9T@2|Bacteria,1V4JB@1239|Firmicutes,24ZUA@186801|Clostridia,27UDH@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF3801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3801
KFPFDFKC_01805	742741.HMPREF9475_01902	0.0	1684.0	COG1961@1|root,COG3505@1|root,COG1961@2|Bacteria,COG3505@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,21YEK@1506553|Lachnoclostridium	186801|Clostridia	L	COG COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,T4SS-DNA_transf,Zn_ribbon_recom
KFPFDFKC_01806	411459.RUMOBE_00651	5.32e-75	224.0	2C5R4@1|root,30S72@2|Bacteria,1V578@1239|Firmicutes,24IJT@186801|Clostridia,3Y0N9@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
KFPFDFKC_01807	658655.HMPREF0988_02916	3.5e-290	794.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,27JJ4@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
KFPFDFKC_01808	411462.DORLON_00194	0.0	1224.0	COG4652@1|root,COG4652@2|Bacteria,1U507@1239|Firmicutes,249H3@186801|Clostridia,27WFW@189330|Dorea	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF1430
KFPFDFKC_01809	1226322.HMPREF1545_00002	1.2e-134	382.0	COG1136@1|root,COG1136@2|Bacteria,1V3NN@1239|Firmicutes,24I94@186801|Clostridia,2N8G1@216572|Oscillospiraceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
KFPFDFKC_01810	1226325.HMPREF1548_03078	6.33e-74	222.0	292P2@1|root,2ZQ6W@2|Bacteria,1V4YF@1239|Firmicutes,24I6C@186801|Clostridia,36RZF@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF3847)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3847
KFPFDFKC_01811	411461.DORFOR_03239	0.0	977.0	COG1196@1|root,COG1196@2|Bacteria,1TPU3@1239|Firmicutes,248HY@186801|Clostridia,27WFG@189330|Dorea	186801|Clostridia	D	COG COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
KFPFDFKC_01812	658086.HMPREF0994_06814	0.0	1228.0	COG0358@1|root,COG3598@1|root,COG0358@2|Bacteria,COG3598@2|Bacteria,1TQKP@1239|Firmicutes,247WJ@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,DUF3991,Toprim_2
KFPFDFKC_01813	1297617.JPJD01000080_gene1397	2.57e-27	99.4	2E8ED@1|root,332SU@2|Bacteria,1VJ6A@1239|Firmicutes,24SJK@186801|Clostridia,26BRY@186813|unclassified Clostridiales	186801|Clostridia	S	Transposon-encoded protein TnpW	-	-	-	-	-	-	-	-	-	-	-	-	TnpW
KFPFDFKC_01814	742741.HMPREF9475_02321	1.75e-151	442.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia,21XRZ@1506553|Lachnoclostridium	186801|Clostridia	U	COG COG3505 Type IV secretory pathway, VirD4 components	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf,TraG-D_C
KFPFDFKC_01815	1235793.C809_02249	2.78e-24	91.3	2CDEH@1|root,32RXK@2|Bacteria,1VA17@1239|Firmicutes,24MPR@186801|Clostridia,27PKS@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Maff2 family	-	-	-	-	-	-	-	-	-	-	-	-	Maff2
KFPFDFKC_01816	1256908.HMPREF0373_01252	1.24e-155	437.0	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,249TG@186801|Clostridia,25V3T@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
KFPFDFKC_01817	622312.ROSEINA2194_04281	4.14e-232	640.0	COG0642@1|root,COG2205@2|Bacteria,1TSIC@1239|Firmicutes,248W8@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
KFPFDFKC_01818	622312.ROSEINA2194_04280	4.28e-177	494.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
KFPFDFKC_01819	483218.BACPEC_00888	0.0	1296.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia,2696C@186813|unclassified Clostridiales	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
KFPFDFKC_01820	665950.HMPREF1025_02698	4.75e-96	280.0	COG1595@1|root,COG1595@2|Bacteria,1TSKU@1239|Firmicutes,24CQA@186801|Clostridia,27JEG@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4
KFPFDFKC_01821	657322.FPR_04700	8.53e-41	134.0	2DDU4@1|root,32U21@2|Bacteria,1VB3J@1239|Firmicutes,24NIV@186801|Clostridia,3WK95@541000|Ruminococcaceae	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
KFPFDFKC_01822	1232452.BAIB02000008_gene1934	4.42e-87	256.0	2C2YH@1|root,2ZBKZ@2|Bacteria,1V3N8@1239|Firmicutes,24FYJ@186801|Clostridia,26B66@186813|unclassified Clostridiales	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
KFPFDFKC_01823	500632.CLONEX_01319	0.0	1040.0	COG1196@1|root,COG1196@2|Bacteria,1UHVD@1239|Firmicutes,25E44@186801|Clostridia	186801|Clostridia	D	COG COG3843 Type IV secretory pathway, VirD2 components (relaxase)	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
KFPFDFKC_01824	1121296.JONJ01000010_gene1994	6.47e-164	460.0	COG3935@1|root,COG3935@2|Bacteria,1TQ65@1239|Firmicutes,249Q8@186801|Clostridia,21Z5B@1506553|Lachnoclostridium	186801|Clostridia	L	N-terminal phage replisome organiser (Phage_rep_org_N)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_rep_org_N
KFPFDFKC_01825	1121296.JONJ01000010_gene1995	1.46e-203	563.0	COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,248F0@186801|Clostridia,21ZQ3@1506553|Lachnoclostridium	186801|Clostridia	L	IstB-like ATP binding protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
KFPFDFKC_01826	1121296.JONJ01000010_gene1996	4.79e-34	117.0	2CM6M@1|root,32SDU@2|Bacteria,1VCHU@1239|Firmicutes,24NMC@186801|Clostridia,2210N@1506553|Lachnoclostridium	186801|Clostridia	S	Transposon-encoded protein TnpW	-	-	-	-	-	-	-	-	-	-	-	-	TnpW
KFPFDFKC_01827	585394.RHOM_01720	0.0	1054.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
KFPFDFKC_01828	97139.C824_04440	4.29e-167	471.0	28HUM@1|root,2Z81B@2|Bacteria,1TNZ2@1239|Firmicutes,248SU@186801|Clostridia,36EXM@31979|Clostridiaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01829	97139.C824_04439	2.48e-69	211.0	COG3451@1|root,COG3451@2|Bacteria,1V74G@1239|Firmicutes,24GFI@186801|Clostridia,36KCQ@31979|Clostridiaceae	186801|Clostridia	U	PrgI family protein	-	-	-	-	-	-	-	-	-	-	-	-	PrgI
KFPFDFKC_01830	585394.RHOM_15395	0.0	1393.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,24BXM@186801|Clostridia	186801|Clostridia	U	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87
KFPFDFKC_01831	742741.HMPREF9475_02326	7.43e-287	825.0	COG0739@1|root,COG0791@1|root,COG0739@2|Bacteria,COG0791@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia,21YV3@1506553|Lachnoclostridium	186801|Clostridia	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,Peptidase_M23
KFPFDFKC_01832	585394.RHOM_15385	1.35e-18	80.1	2F6I0@1|root,33Z10@2|Bacteria,1VWYS@1239|Firmicutes,24PWX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01833	1235799.C818_03909	7.9e-189	549.0	COG2433@1|root,COG2433@2|Bacteria,1V0VN@1239|Firmicutes,24ABK@186801|Clostridia,27MDE@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4366)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4366
KFPFDFKC_01834	585394.RHOM_15375	0.0	1087.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	-	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	DUF3945,Topoisom_bac,Toprim,Toprim_Crpt
KFPFDFKC_01835	511680.BUTYVIB_00633	1.99e-20	84.0	2F6CB@1|root,33YVQ@2|Bacteria,1VWV0@1239|Firmicutes,2523Z@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01836	1280681.AUJZ01000002_gene1442	1.53e-90	277.0	COG0237@1|root,COG1247@1|root,COG0237@2|Bacteria,COG1247@2|Bacteria,1VHNA@1239|Firmicutes,24KBU@186801|Clostridia,4BW2U@830|Butyrivibrio	186801|Clostridia	H	dephospho-CoA kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01837	483218.BACPEC_01783	4.94e-59	182.0	2DP25@1|root,3307U@2|Bacteria,1VFQB@1239|Firmicutes,24RCV@186801|Clostridia,269UA@186813|unclassified Clostridiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01838	1235799.C818_03894	0.0	3464.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,1TPQA@1239|Firmicutes,2491X@186801|Clostridia,27J19@186928|unclassified Lachnospiraceae	186801|Clostridia	KL	helicase C-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3849,Helicase_C,ResIII,SNF2_N
KFPFDFKC_01839	483218.BACPEC_01788	2.55e-234	644.0	28JMS@1|root,2Z9E9@2|Bacteria,1UZBX@1239|Firmicutes,24D7A@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01840	483218.BACPEC_01789	6.79e-79	234.0	28P4A@1|root,2ZBZJ@2|Bacteria,1V39Y@1239|Firmicutes,24GP0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01841	622312.ROSEINA2194_03345	1.8e-16	75.9	2C0GJ@1|root,2Z7PN@2|Bacteria,1V0HT@1239|Firmicutes,24FCI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01842	622312.ROSEINA2194_03345	3.04e-131	375.0	2C0GJ@1|root,2Z7PN@2|Bacteria,1V0HT@1239|Firmicutes,24FCI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01843	483218.BACPEC_01792	1.9e-116	337.0	28JQQ@1|root,2Z9GH@2|Bacteria,1UZ31@1239|Firmicutes,24EXK@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01844	483218.BACPEC_01793	9.8e-158	442.0	2DBMJ@1|root,2Z9Z8@2|Bacteria,1UTJA@1239|Firmicutes,24EBB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01845	483218.BACPEC_01794	2.24e-74	223.0	COG0745@1|root,COG0745@2|Bacteria,1V65U@1239|Firmicutes,24HUB@186801|Clostridia,2693F@186813|unclassified Clostridiales	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
KFPFDFKC_01846	483218.BACPEC_01795	0.0	2424.0	COG1669@1|root,COG4227@1|root,COG1669@2|Bacteria,COG4227@2|Bacteria,1TQN4@1239|Firmicutes,2482H@186801|Clostridia,268CY@186813|unclassified Clostridiales	186801|Clostridia	L	Domain of unknown function (DUF4316)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3849,DUF4316,Peptidase_M78,YodL,zf-CHC2
KFPFDFKC_01847	483218.BACPEC_01796	3.3e-39	130.0	2DP0F@1|root,3321I@2|Bacteria,1VEWX@1239|Firmicutes,24TDI@186801|Clostridia	186801|Clostridia	S	Putative tranposon-transfer assisting protein	-	-	-	-	-	-	-	-	-	-	-	-	TTRAP
KFPFDFKC_01848	742765.HMPREF9457_01691	3.23e-51	171.0	COG4804@1|root,COG4804@2|Bacteria,1TP7Q@1239|Firmicutes,24A19@186801|Clostridia,27WRE@189330|Dorea	186801|Clostridia	S	Protein of unknown function (DUF1016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
KFPFDFKC_01849	97139.C824_04617	4.66e-236	660.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,2481D@186801|Clostridia,36E9W@31979|Clostridiaceae	186801|Clostridia	U	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
KFPFDFKC_01850	1235793.C809_00188	1.91e-54	172.0	296J0@1|root,30WDX@2|Bacteria,1UICE@1239|Firmicutes,25EHH@186801|Clostridia,27N3K@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
KFPFDFKC_01853	562743.JH976434_gene1895	1.45e-105	324.0	2B6ZF@1|root,31ZZQ@2|Bacteria,1VIW5@1239|Firmicutes,4HXXT@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01855	562743.JH976434_gene1893	1.24e-208	606.0	COG0419@1|root,COG0419@2|Bacteria,1TSW9@1239|Firmicutes	1239|Firmicutes	L	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF3732
KFPFDFKC_01858	1469948.JPNB01000001_gene446	6.78e-143	442.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,36E1W@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,dCache_1
KFPFDFKC_01859	585394.RHOM_04435	7.33e-67	206.0	COG3976@1|root,COG3976@2|Bacteria,1V72R@1239|Firmicutes,24JFD@186801|Clostridia	186801|Clostridia	S	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01860	585394.RHOM_04440	2.66e-30	108.0	2DRX4@1|root,33DGR@2|Bacteria,1VKQ3@1239|Firmicutes,24URP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01861	585394.RHOM_04450	5.97e-98	286.0	COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,24FTH@186801|Clostridia	186801|Clostridia	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
KFPFDFKC_01862	585394.RHOM_04455	1.56e-194	543.0	COG0679@1|root,COG0679@2|Bacteria,1TR9W@1239|Firmicutes,24AQF@186801|Clostridia	186801|Clostridia	S	Transporter, auxin efflux carrier (AEC) family protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
KFPFDFKC_01863	585394.RHOM_04460	0.0	1078.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia	186801|Clostridia	H	Acetolactate synthase, large subunit	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
KFPFDFKC_01864	585394.RHOM_04465	1.03e-101	296.0	COG0440@1|root,COG0440@2|Bacteria,1V3PG@1239|Firmicutes,24A0D@186801|Clostridia	186801|Clostridia	E	acetolactate synthase, small	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
KFPFDFKC_01865	585394.RHOM_04470	1.43e-182	516.0	28JB6@1|root,2Z960@2|Bacteria,1U83T@1239|Firmicutes,24BAY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01866	585394.RHOM_04475	3.61e-129	374.0	COG4976@1|root,COG4976@2|Bacteria,1UHZM@1239|Firmicutes,24A6U@186801|Clostridia	186801|Clostridia	S	Methyltransferase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
KFPFDFKC_01867	622312.ROSEINA2194_03327	1.11e-169	478.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,24940@186801|Clostridia	186801|Clostridia	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
KFPFDFKC_01868	622312.ROSEINA2194_03328	0.0	1028.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
KFPFDFKC_01869	622312.ROSEINA2194_03329	4.65e-259	712.0	COG1453@1|root,COG1453@2|Bacteria,1TQ5N@1239|Firmicutes,247SD@186801|Clostridia	186801|Clostridia	C	aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
KFPFDFKC_01870	1408324.JNJK01000005_gene1128	4.99e-194	551.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,27JK2@186928|unclassified Lachnospiraceae	186801|Clostridia	F	Amidohydrolase family	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
KFPFDFKC_01871	585394.RHOM_11030	7.5e-129	370.0	COG0671@1|root,COG0671@2|Bacteria,1V2ZH@1239|Firmicutes,24HRY@186801|Clostridia	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,PAP2_3
KFPFDFKC_01872	622312.ROSEINA2194_03332	2e-224	642.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia	186801|Clostridia	M	ErfK YbiS YcfS YnhG	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
KFPFDFKC_01873	622312.ROSEINA2194_00581	7.97e-37	129.0	COG1476@1|root,COG1476@2|Bacteria,1VCHW@1239|Firmicutes,24TP0@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01875	585394.RHOM_03740	2.79e-191	536.0	COG0183@1|root,COG0183@2|Bacteria,1UHVW@1239|Firmicutes,248BM@186801|Clostridia	186801|Clostridia	I	stage v sporulation protein ad	spoVAD	-	-	ko:K06406	-	-	-	-	ko00000	-	-	-	SpoVAD
KFPFDFKC_01876	622312.ROSEINA2194_00584	1.28e-68	208.0	2ANER@1|root,315MJ@2|Bacteria,1V6SU@1239|Firmicutes,24JBZ@186801|Clostridia	186801|Clostridia	S	Stage V sporulation protein AE	spoVAE	-	-	ko:K06407	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
KFPFDFKC_01877	585394.RHOM_03800	1.1e-90	266.0	COG0537@1|root,COG0537@2|Bacteria,1V3BE@1239|Firmicutes,24H73@186801|Clostridia	186801|Clostridia	FG	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HIT
KFPFDFKC_01878	585394.RHOM_03805	7.34e-222	612.0	COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,248GA@186801|Clostridia	186801|Clostridia	G	2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
KFPFDFKC_01879	622312.ROSEINA2194_00348	5.11e-155	439.0	COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,24BQA@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
KFPFDFKC_01881	585394.RHOM_03825	5.26e-281	780.0	COG1219@1|root,COG1219@2|Bacteria,1TPDI@1239|Firmicutes,24AEG@186801|Clostridia	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX_1	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
KFPFDFKC_01882	622312.ROSEINA2194_01915	2.36e-50	183.0	COG0840@1|root,COG5000@1|root,COG0840@2|Bacteria,COG5000@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal,dCache_1
KFPFDFKC_01883	1235793.C809_03946	4.17e-26	110.0	COG0840@1|root,COG5000@1|root,COG0840@2|Bacteria,COG5000@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,27JJS@186928|unclassified Lachnospiraceae	186801|Clostridia	NT	Pfam:Cache_1	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal,dCache_1
KFPFDFKC_01884	585394.RHOM_03830	1.78e-290	806.0	COG1404@1|root,COG1404@2|Bacteria,1TQE0@1239|Firmicutes,25B1A@186801|Clostridia	186801|Clostridia	O	COG COG1404 Subtilisin-like serine proteases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
KFPFDFKC_01888	585394.RHOM_11710	1.83e-161	473.0	COG0845@1|root,COG0845@2|Bacteria,1V046@1239|Firmicutes,24ANJ@186801|Clostridia	186801|Clostridia	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
KFPFDFKC_01889	585394.RHOM_11705	1.68e-136	389.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
KFPFDFKC_01890	585394.RHOM_11700	2.65e-214	614.0	COG0845@1|root,COG0845@2|Bacteria,1UZ3U@1239|Firmicutes,24BV7@186801|Clostridia	186801|Clostridia	M	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
KFPFDFKC_01891	585394.RHOM_11695	6.42e-221	618.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
KFPFDFKC_01892	585394.RHOM_11690	9.49e-175	500.0	COG4641@1|root,COG4641@2|Bacteria,1UYE0@1239|Firmicutes,24D1Q@186801|Clostridia	186801|Clostridia	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
KFPFDFKC_01893	622312.ROSEINA2194_04229	5.68e-297	811.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
KFPFDFKC_01894	585394.RHOM_11680	1.52e-120	344.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia	186801|Clostridia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
KFPFDFKC_01895	585394.RHOM_11675	7.58e-121	355.0	29TA1@1|root,30EH1@2|Bacteria,1V43N@1239|Firmicutes,24IGU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01897	585394.RHOM_11420	1.43e-177	509.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,24YIP@186801|Clostridia	186801|Clostridia	G	hydrolase, family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
KFPFDFKC_01898	622312.ROSEINA2194_02225	7.06e-81	250.0	COG4862@1|root,COG4862@2|Bacteria	2|Bacteria	NOT	establishment of competence for transformation	mecA	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K16511	-	-	-	-	ko00000	-	-	-	MecA
KFPFDFKC_01901	1235790.C805_01468	1.9e-74	238.0	COG1527@1|root,COG1527@2|Bacteria,1U1QE@1239|Firmicutes,24A4E@186801|Clostridia	186801|Clostridia	C	Archaeal vacuolar-type H -ATPase subunit C	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
KFPFDFKC_01902	397288.C806_01355	6.26e-255	723.0	COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,249YV@186801|Clostridia,27KFU@186928|unclassified Lachnospiraceae	186801|Clostridia	U	V-type ATPase 116kDa subunit family	ntpI	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
KFPFDFKC_01903	397290.C810_03102	7.44e-57	180.0	COG0636@1|root,COG0636@2|Bacteria,1VAGE@1239|Firmicutes,24RB6@186801|Clostridia,27MUF@186928|unclassified Lachnospiraceae	186801|Clostridia	C	ATP synthase subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
KFPFDFKC_01904	397288.C806_01357	2.68e-49	158.0	COG1436@1|root,COG1436@2|Bacteria,1VEN1@1239|Firmicutes,24K2E@186801|Clostridia,27NKU@186928|unclassified Lachnospiraceae	186801|Clostridia	C	ATP synthase (F/14-kDa) subunit	-	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
KFPFDFKC_01905	357809.Cphy_3443	1.99e-21	94.0	COG1390@1|root,COG1390@2|Bacteria,1V7UJ@1239|Firmicutes,24ICM@186801|Clostridia,21Z0G@1506553|Lachnoclostridium	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	vATP-synt_E
KFPFDFKC_01906	397288.C806_01359	0.0	926.0	COG1155@1|root,COG1155@2|Bacteria,1TPGS@1239|Firmicutes,24882@186801|Clostridia,27IS3@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	ntpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
KFPFDFKC_01907	1235790.C805_01474	2.4e-273	754.0	COG1156@1|root,COG1156@2|Bacteria,1VSU1@1239|Firmicutes,2496H@186801|Clostridia,25VDA@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	ntpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
KFPFDFKC_01908	1235790.C805_01475	1.76e-103	304.0	COG1394@1|root,COG1394@2|Bacteria,1TQ4P@1239|Firmicutes,24Z7J@186801|Clostridia,25WFD@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
KFPFDFKC_01909	1235800.C819_00237	2.78e-173	497.0	COG3434@1|root,COG3434@2|Bacteria,1TPWC@1239|Firmicutes,248M1@186801|Clostridia,27J37@186928|unclassified Lachnospiraceae	186801|Clostridia	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
KFPFDFKC_01910	622312.ROSEINA2194_02683	3.27e-292	805.0	COG2326@1|root,COG2326@2|Bacteria,1TQQR@1239|Firmicutes,249HE@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	pap	-	-	-	-	-	-	-	-	-	-	-	PPK2
KFPFDFKC_01911	1408323.JQKK01000028_gene637	2.52e-40	139.0	29PCB@1|root,30AAJ@2|Bacteria,1V4H2@1239|Firmicutes,24IF4@186801|Clostridia,27M51@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01912	511680.BUTYVIB_00600	2.01e-45	162.0	2DXU6@1|root,346M3@2|Bacteria,1VYTI@1239|Firmicutes,24W32@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01913	97139.C824_06059	5.15e-122	360.0	COG5464@1|root,COG5464@2|Bacteria,1V3CA@1239|Firmicutes,24H4R@186801|Clostridia,36NMB@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
KFPFDFKC_01914	1232447.BAHW02000040_gene2696	5.38e-21	96.3	2F5M1@1|root,33Y66@2|Bacteria,1VVWD@1239|Firmicutes,24RWD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01916	768704.Desmer_3418	5.25e-61	228.0	2FKA7@1|root,34BXU@2|Bacteria,1TX1M@1239|Firmicutes,24X8E@186801|Clostridia	186801|Clostridia	-	-	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23
KFPFDFKC_01917	585394.RHOM_03220	0.0	904.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
KFPFDFKC_01918	585394.RHOM_03230	0.0	1043.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
KFPFDFKC_01919	511680.BUTYVIB_00807	5.96e-76	230.0	COG1051@1|root,COG1051@2|Bacteria,1V3IM@1239|Firmicutes,24HEA@186801|Clostridia,4BZAJ@830|Butyrivibrio	186801|Clostridia	F	NUDIX domain	mutX	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
KFPFDFKC_01920	397291.C804_02341	1.78e-78	246.0	COG0127@1|root,COG0127@2|Bacteria,1V85S@1239|Firmicutes,24KX4@186801|Clostridia,27NVI@186928|unclassified Lachnospiraceae	186801|Clostridia	F	Ham1 family	-	-	-	-	-	-	-	-	-	-	-	-	Ham1p_like
KFPFDFKC_01921	585394.RHOM_03285	1.53e-256	711.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
KFPFDFKC_01922	585394.RHOM_03290	6.78e-127	362.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia	186801|Clostridia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
KFPFDFKC_01923	585394.RHOM_03295	6.72e-269	740.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
KFPFDFKC_01924	585394.RHOM_03300	0.0	1168.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
KFPFDFKC_01925	585394.RHOM_03305	4.36e-133	378.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
KFPFDFKC_01926	622312.ROSEINA2194_04415	6.74e-200	556.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia	186801|Clostridia	E	carbamate kinase	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
KFPFDFKC_01927	585394.RHOM_03315	0.0	965.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia	186801|Clostridia	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
KFPFDFKC_01928	515620.EUBELI_00156	2.34e-253	704.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,25VVF@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
KFPFDFKC_01929	515620.EUBELI_00158	2.53e-164	463.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1V2SW@1239|Firmicutes,24GTR@186801|Clostridia,25XBA@186806|Eubacteriaceae	186801|Clostridia	K	COG2207 AraC-type DNA-binding domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
KFPFDFKC_01930	585394.RHOM_03320	0.0	1521.0	COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,248YP@186801|Clostridia	186801|Clostridia	G	Glycosyltransferase 36 associated	-	-	2.4.1.20	ko:K00702	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000	-	GT36	-	Glyco_hydro_36,Glyco_transf_36
KFPFDFKC_01931	585394.RHOM_03325	4.2e-223	617.0	COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,24A4M@186801|Clostridia	186801|Clostridia	K	lacI family	-	-	-	ko:K02529,ko:K03604	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
KFPFDFKC_01932	585394.RHOM_03330	1.99e-263	731.0	COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
KFPFDFKC_01933	622312.ROSEINA2194_02493	1.01e-193	540.0	COG1175@1|root,COG1175@2|Bacteria,1TS63@1239|Firmicutes,2489M@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport systems permease components	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
KFPFDFKC_01934	622312.ROSEINA2194_02492	4.23e-172	484.0	COG0395@1|root,COG0395@2|Bacteria,1TS0R@1239|Firmicutes,248UX@186801|Clostridia	186801|Clostridia	P	ABC-type sugar transport system, permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
KFPFDFKC_01936	585394.RHOM_03360	0.0	1453.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia	186801|Clostridia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
KFPFDFKC_01937	585394.RHOM_03370	0.0	1732.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
KFPFDFKC_01938	585394.RHOM_03375	3.25e-191	546.0	COG1315@1|root,COG1315@2|Bacteria,1TR7W@1239|Firmicutes,24B18@186801|Clostridia	186801|Clostridia	L	PALM domain HD hydrolase domain and	-	-	-	ko:K09749	-	-	-	-	ko00000	-	-	-	FapA,Jag_N
KFPFDFKC_01939	622312.ROSEINA2194_02482	1.32e-20	82.4	2EGDA@1|root,33A54@2|Bacteria,1VKC8@1239|Firmicutes,24UDV@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01940	585394.RHOM_03385	1.56e-228	640.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,1UI34@1239|Firmicutes,25F0K@186801|Clostridia	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
KFPFDFKC_01941	622312.ROSEINA2194_02480	4.06e-42	140.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,24R0X@186801|Clostridia	186801|Clostridia	T	Belongs to the anti-sigma-factor antagonist family	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
KFPFDFKC_01942	585394.RHOM_03395	4.44e-69	212.0	COG2172@1|root,COG2172@2|Bacteria,1V6V2@1239|Firmicutes,24JPT@186801|Clostridia	186801|Clostridia	F	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition	spoIIAB	-	2.7.11.1	ko:K06379	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c_2
KFPFDFKC_01943	585394.RHOM_03400	4.73e-101	301.0	COG1191@1|root,COG1191@2|Bacteria,1TP3Q@1239|Firmicutes,2487Z@186801|Clostridia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigF	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
KFPFDFKC_01944	622312.ROSEINA2194_02476	1.15e-104	311.0	COG1011@1|root,COG1011@2|Bacteria,1UIG9@1239|Firmicutes,25EMR@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
KFPFDFKC_01945	585394.RHOM_03410	6.2e-61	205.0	COG3064@1|root,COG3064@2|Bacteria,1V52J@1239|Firmicutes,24HMZ@186801|Clostridia	186801|Clostridia	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01946	1121344.JHZO01000005_gene292	7.18e-70	230.0	COG2206@1|root,COG2206@2|Bacteria,1VV1Y@1239|Firmicutes,2502J@186801|Clostridia	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
KFPFDFKC_01947	1123075.AUDP01000001_gene2395	6.31e-97	288.0	COG0664@1|root,COG0664@2|Bacteria,1TSP9@1239|Firmicutes,24FRD@186801|Clostridia,3WIW5@541000|Ruminococcaceae	186801|Clostridia	K	Cyclic nucleotide-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
KFPFDFKC_01948	1226325.HMPREF1548_02216	2.75e-118	343.0	COG1145@1|root,COG1145@2|Bacteria,1TPAZ@1239|Firmicutes,249NJ@186801|Clostridia,36F9G@31979|Clostridiaceae	186801|Clostridia	C	binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
KFPFDFKC_01949	585394.RHOM_06150	0.0	906.0	COG0369@1|root,COG1151@2|Bacteria,1TP8X@1239|Firmicutes,247IN@186801|Clostridia	186801|Clostridia	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
KFPFDFKC_01950	483218.BACPEC_02145	1.5e-190	543.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1TSFE@1239|Firmicutes,25KM5@186801|Clostridia,26AZA@186813|unclassified Clostridiales	186801|Clostridia	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
KFPFDFKC_01951	585394.RHOM_15140	0.0	1047.0	COG3507@1|root,COG3507@2|Bacteria,1TSKZ@1239|Firmicutes,24BRZ@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,CBM_6,Esterase,Glyco_hydro_43
KFPFDFKC_01953	478749.BRYFOR_08361	6.34e-20	89.0	COG1785@1|root,COG1785@2|Bacteria,1TQCI@1239|Firmicutes,248GG@186801|Clostridia	186801|Clostridia	P	Belongs to the alkaline phosphatase family	phoA	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase,TAT_signal
KFPFDFKC_01954	755731.Clo1100_0192	3.91e-15	73.6	COG1501@1|root,COG1501@2|Bacteria,1UJ1V@1239|Firmicutes,24AVU@186801|Clostridia,36HI8@31979|Clostridiaceae	186801|Clostridia	G	Alpha galactosidase A	-	-	-	-	-	-	-	-	-	-	-	-	Melibiase_2
KFPFDFKC_01955	1506994.JNLQ01000002_gene2343	6.36e-33	124.0	COG1501@1|root,COG1501@2|Bacteria,1UJ1V@1239|Firmicutes,24AVU@186801|Clostridia,4BW4M@830|Butyrivibrio	186801|Clostridia	G	Alpha galactosidase A	-	-	-	-	-	-	-	-	-	-	-	-	Melibiase_2
KFPFDFKC_01956	1280694.AUJQ01000008_gene114	5.06e-47	162.0	COG1501@1|root,COG1501@2|Bacteria,1UJ1V@1239|Firmicutes,24AVU@186801|Clostridia	186801|Clostridia	G	Alpha galactosidase A	-	-	-	-	-	-	-	-	-	-	-	-	Melibiase_2
KFPFDFKC_01957	658086.HMPREF0994_04310	1.83e-10	63.9	COG1501@1|root,COG1501@2|Bacteria,1UJ1V@1239|Firmicutes,24AVU@186801|Clostridia,27KBE@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Alpha galactosidase A	-	-	-	-	-	-	-	-	-	-	-	-	Melibiase_2
KFPFDFKC_01958	457412.RSAG_02489	1.8e-291	799.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,3WI10@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
KFPFDFKC_01959	457412.RSAG_02488	1.17e-85	261.0	COG1609@1|root,COG1609@2|Bacteria,1UM0E@1239|Firmicutes,25B2H@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
KFPFDFKC_01960	585394.RHOM_11640	3.42e-129	366.0	2DBP0@1|root,2ZA6P@2|Bacteria,1V58E@1239|Firmicutes,24GG5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01961	622312.ROSEINA2194_04316	1.28e-80	241.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24MRZ@186801|Clostridia	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
KFPFDFKC_01962	585394.RHOM_05265	3.77e-93	315.0	2C4YK@1|root,342PE@2|Bacteria,1VWY9@1239|Firmicutes,24TZZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01964	861454.HMPREF9099_02905	9.78e-07	48.9	COG3514@1|root,COG3514@2|Bacteria,1VFWT@1239|Firmicutes,24S45@186801|Clostridia,27PNA@186928|unclassified Lachnospiraceae	186801|Clostridia	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
KFPFDFKC_01965	397287.C807_01799	1.26e-08	50.8	2BEY0@1|root,328PP@2|Bacteria,1UUMP@1239|Firmicutes,25766@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01970	1235802.C823_05603	1.47e-135	428.0	COG1040@1|root,COG1040@2|Bacteria,1UZTG@1239|Firmicutes,24CG1@186801|Clostridia,25Y2V@186806|Eubacteriaceae	186801|Clostridia	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01971	1536769.P40081_27475	4.58e-15	78.6	COG2856@1|root,COG2856@2|Bacteria,1VF46@1239|Firmicutes	1239|Firmicutes	E	Pfam:DUF955	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
KFPFDFKC_01974	585394.RHOM_08305	2.48e-301	828.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
KFPFDFKC_01975	585394.RHOM_08300	2.69e-41	140.0	COG5341@1|root,COG5341@2|Bacteria	2|Bacteria	S	NusG domain II	-	-	-	-	-	-	-	-	-	-	-	-	NusG_II
KFPFDFKC_01976	585394.RHOM_08295	6.41e-80	241.0	COG4769@1|root,COG4769@2|Bacteria,1V1M0@1239|Firmicutes,24MZC@186801|Clostridia	186801|Clostridia	S	Heptaprenyl diphosphate synthase component I	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	Hpre_diP_synt_I
KFPFDFKC_01977	622312.ROSEINA2194_00524	1.89e-111	323.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
KFPFDFKC_01978	585394.RHOM_08285	1.5e-215	597.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
KFPFDFKC_01979	585394.RHOM_08280	5.98e-60	189.0	COG3027@1|root,COG3027@2|Bacteria,1V4E5@1239|Firmicutes,24HQR@186801|Clostridia	186801|Clostridia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
KFPFDFKC_01980	622312.ROSEINA2194_00527	7.65e-310	871.0	COG0826@1|root,COG0826@2|Bacteria,1TQS1@1239|Firmicutes,24909@186801|Clostridia	186801|Clostridia	O	peptidase U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
KFPFDFKC_01981	585394.RHOM_08270	1.82e-225	633.0	COG0772@1|root,COG0772@2|Bacteria,1TQ82@1239|Firmicutes,248QS@186801|Clostridia	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FHA,FTSW_RODA_SPOVE
KFPFDFKC_01982	585394.RHOM_08265	1.45e-237	667.0	COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,2486R@186801|Clostridia	186801|Clostridia	M	Penicillin-binding Protein	pbpA2	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
KFPFDFKC_01983	585394.RHOM_08260	1.99e-94	276.0	COG1051@1|root,COG1051@2|Bacteria,1V4E6@1239|Firmicutes,24HPT@186801|Clostridia	186801|Clostridia	F	Belongs to the Nudix hydrolase family	apfA	-	-	-	-	-	-	-	-	-	-	-	NUDIX
KFPFDFKC_01984	622312.ROSEINA2194_01757	4.77e-52	166.0	2CSSR@1|root,32SRT@2|Bacteria,1VKAJ@1239|Firmicutes,24N3Y@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01985	622312.ROSEINA2194_01756	2.23e-43	158.0	2E3Z2@1|root,32YW0@2|Bacteria,1VGF4@1239|Firmicutes,24PIY@186801|Clostridia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	DUF2953
KFPFDFKC_01986	585394.RHOM_08245	1.01e-81	244.0	COG3874@1|root,COG3874@2|Bacteria,1V99U@1239|Firmicutes,24K00@186801|Clostridia	186801|Clostridia	S	Sporulation protein YtfJ	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
KFPFDFKC_01987	1235798.C817_02525	1.12e-08	52.0	2ERI6@1|root,33J3P@2|Bacteria,1VMBI@1239|Firmicutes,24VNP@186801|Clostridia,27VXK@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_01988	585394.RHOM_08235	1.9e-145	410.0	COG0698@1|root,COG0698@2|Bacteria,1TQQJ@1239|Firmicutes,249IB@186801|Clostridia	186801|Clostridia	G	Ribose Galactose Isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3666,LacAB_rpiB
KFPFDFKC_01989	585394.RHOM_08230	4.53e-204	565.0	COG3717@1|root,COG3717@2|Bacteria,1TP4X@1239|Firmicutes,24A00@186801|Clostridia	186801|Clostridia	G	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate	kduI	-	5.3.1.17	ko:K01815	ko00040,map00040	-	R04383	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
KFPFDFKC_01990	585394.RHOM_08225	0.0	881.0	COG1904@1|root,COG1904@2|Bacteria,1TRI0@1239|Firmicutes,248C0@186801|Clostridia	186801|Clostridia	G	glucuronate isomerase	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
KFPFDFKC_01991	585394.RHOM_08220	2.1e-197	552.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	ccpA	-	-	ko:K02529,ko:K03487	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
KFPFDFKC_01992	585394.RHOM_08210	0.0	871.0	COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,248J5@186801|Clostridia	186801|Clostridia	G	Mannitol dehydrogenase	-	-	1.1.1.58	ko:K00041	ko00040,ko01100,map00040,map01100	M00631	R02555	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
KFPFDFKC_01993	585394.RHOM_08205	5.9e-304	835.0	COG2721@1|root,COG2721@2|Bacteria,1TPTX@1239|Firmicutes,24AEC@186801|Clostridia	186801|Clostridia	G	D-galactarate dehydratase Altronate hydrolase	uxaA	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
KFPFDFKC_01994	585394.RHOM_04075	3.94e-176	492.0	COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,24903@186801|Clostridia	186801|Clostridia	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
KFPFDFKC_01995	1235793.C809_01107	7.58e-202	575.0	COG1680@1|root,COG1680@2|Bacteria,1TSXS@1239|Firmicutes,24H20@186801|Clostridia	186801|Clostridia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
KFPFDFKC_01996	1449050.JNLE01000003_gene3046	1.39e-89	306.0	COG2207@1|root,COG2207@2|Bacteria,1UZQJ@1239|Firmicutes,24GN0@186801|Clostridia,36HGH@31979|Clostridiaceae	186801|Clostridia	K	transcriptional regulator, arac family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
KFPFDFKC_01997	1304866.K413DRAFT_2462	8.32e-230	650.0	COG1653@1|root,COG1653@2|Bacteria,1TW09@1239|Firmicutes,24BZW@186801|Clostridia,36G3C@31979|Clostridiaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
KFPFDFKC_01998	1304866.K413DRAFT_2463	7.07e-146	420.0	COG4209@1|root,COG4209@2|Bacteria,1TP33@1239|Firmicutes,247UA@186801|Clostridia,36GXV@31979|Clostridiaceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
KFPFDFKC_01999	1298920.KI911353_gene1189	1.36e-146	419.0	COG0395@1|root,COG0395@2|Bacteria,1TSX2@1239|Firmicutes,24891@186801|Clostridia,222N7@1506553|Lachnoclostridium	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K17320	ko02010,map02010	M00207,M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
KFPFDFKC_02000	1280668.ATVT01000001_gene794	1.39e-93	281.0	COG2755@1|root,COG2755@2|Bacteria,1V2SC@1239|Firmicutes,24H62@186801|Clostridia,4BWRN@830|Butyrivibrio	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
KFPFDFKC_02001	515622.bpr_I1585	1.68e-210	602.0	COG3507@1|root,COG3507@2|Bacteria,1UDW2@1239|Firmicutes,24A81@186801|Clostridia,4BYGR@830|Butyrivibrio	186801|Clostridia	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
KFPFDFKC_02002	483218.BACPEC_01722	6.05e-276	776.0	COG0666@1|root,COG3507@1|root,COG0666@2|Bacteria,COG3507@2|Bacteria,1TP5K@1239|Firmicutes,247R2@186801|Clostridia,26AET@186813|unclassified Clostridiales	186801|Clostridia	G	Glycosyl hydrolases family 43	-	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	Ank_2,Ank_4,Glyco_hydro_43
KFPFDFKC_02004	585394.RHOM_08175	1.65e-267	744.0	COG5434@1|root,COG5434@2|Bacteria,1TQQW@1239|Firmicutes,24A0R@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
KFPFDFKC_02005	585394.RHOM_08170	1.64e-165	467.0	COG1082@1|root,COG1082@2|Bacteria,1U81K@1239|Firmicutes,2492P@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
KFPFDFKC_02006	180332.JTGN01000010_gene4424	2.08e-58	203.0	COG5492@1|root,COG5492@2|Bacteria,1UINF@1239|Firmicutes,25EP2@186801|Clostridia	186801|Clostridia	N	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
KFPFDFKC_02007	1280688.AUJB01000008_gene1258	2.69e-35	120.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,3NHEH@46205|Pseudobutyrivibrio	186801|Clostridia	J	Ribosomal L28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
KFPFDFKC_02008	585394.RHOM_07260	2.12e-72	218.0	COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,24JIA@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
KFPFDFKC_02009	585394.RHOM_07265	0.0	902.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,247XI@186801|Clostridia	186801|Clostridia	S	DAK2 domain fusion protein YloV	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
KFPFDFKC_02010	585394.RHOM_07270	0.0	998.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
KFPFDFKC_02011	585394.RHOM_07275	7.8e-38	127.0	2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,24QPW@186801|Clostridia	186801|Clostridia	S	'small, acid-soluble spore protein	sasP	-	-	ko:K06421	-	-	-	-	ko00000	-	-	-	SASP
KFPFDFKC_02012	585394.RHOM_07295	9.78e-260	713.0	COG4225@1|root,COG4225@2|Bacteria,1TRJ7@1239|Firmicutes,24806@186801|Clostridia	186801|Clostridia	S	Glycosyl Hydrolase Family 88	-	-	3.2.1.172	ko:K15532	-	-	-	-	ko00000,ko01000	-	GH105	-	Glyco_hydro_88
KFPFDFKC_02013	665956.HMPREF1032_02998	3.76e-60	199.0	COG1266@1|root,COG1266@2|Bacteria,1USCY@1239|Firmicutes,24F5M@186801|Clostridia,3WMPA@541000|Ruminococcaceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
KFPFDFKC_02014	585394.RHOM_07300	0.0	986.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,248RK@186801|Clostridia	186801|Clostridia	K	Fibronectin-binding protein	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
KFPFDFKC_02017	511680.BUTYVIB_01373	1.29e-75	247.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,248ND@186801|Clostridia,4BX4E@830|Butyrivibrio	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87
KFPFDFKC_02018	1280698.AUJS01000017_gene1782	0.0	944.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,27W5B@189330|Dorea	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
KFPFDFKC_02019	483218.BACPEC_00199	4.87e-112	343.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,248ND@186801|Clostridia,268HK@186813|unclassified Clostridiales	186801|Clostridia	U	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87
KFPFDFKC_02020	1235792.C808_03871	1.53e-272	764.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,27JJ4@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
KFPFDFKC_02021	483218.BACPEC_00199	0.0	931.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,248ND@186801|Clostridia,268HK@186813|unclassified Clostridiales	186801|Clostridia	U	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87
KFPFDFKC_02022	483218.BACPEC_00198	1.98e-106	308.0	28XQJ@1|root,2ZJM8@2|Bacteria,1V2X9@1239|Firmicutes,25FQ2@186801|Clostridia,26CQI@186813|unclassified Clostridiales	186801|Clostridia	S	PrgI family protein	-	-	-	-	-	-	-	-	-	-	-	-	PrgI
KFPFDFKC_02023	500632.CLONEX_00584	1.85e-99	288.0	28MPH@1|root,2ZAYS@2|Bacteria,1TT66@1239|Firmicutes,24FFZ@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4313
KFPFDFKC_02024	500632.CLONEX_00583	2.05e-192	535.0	2DB6V@1|root,2Z7IJ@2|Bacteria,1TRNS@1239|Firmicutes,24ANE@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02025	742765.HMPREF9457_02491	3.06e-77	231.0	299KT@1|root,2ZWP8@2|Bacteria,1V5IJ@1239|Firmicutes,24N53@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02026	397287.C807_02675	7.03e-55	176.0	COG5658@1|root,COG5658@2|Bacteria,1VB6E@1239|Firmicutes,24MSY@186801|Clostridia,27NNV@186928|unclassified Lachnospiraceae	186801|Clostridia	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	SdpI
KFPFDFKC_02027	1280698.AUJS01000060_gene928	7.65e-123	350.0	COG0655@1|root,COG0655@2|Bacteria,1TSDE@1239|Firmicutes,24CNT@186801|Clostridia,27WEE@189330|Dorea	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
KFPFDFKC_02028	742765.HMPREF9457_02492	0.0	1447.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia	186801|Clostridia	U	COG COG3505 Type IV secretory pathway, VirD4 components	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf,TraG-D_C
KFPFDFKC_02029	500632.CLONEX_00577	3.83e-257	706.0	2CF7U@1|root,2Z7U3@2|Bacteria,1UYHD@1239|Firmicutes,24C76@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3801
KFPFDFKC_02030	500632.CLONEX_00576	2.01e-84	249.0	2CJ59@1|root,2ZGJ1@2|Bacteria,1V30K@1239|Firmicutes,24H8I@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02031	742765.HMPREF9457_02495	5.07e-204	573.0	28M18@1|root,2ZAG5@2|Bacteria,1UBEC@1239|Firmicutes,24DSX@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02032	742765.HMPREF9457_02496	0.0	920.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,248VT@186801|Clostridia,27WFN@189330|Dorea	186801|Clostridia	U	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
KFPFDFKC_02033	742765.HMPREF9457_02497	7.4e-71	213.0	2DM28@1|root,31EE5@2|Bacteria,1VBAV@1239|Firmicutes,24NVF@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	MobC
KFPFDFKC_02034	500632.CLONEX_00572	2.93e-119	341.0	28JWV@1|root,2Z9ME@2|Bacteria,1TWU8@1239|Firmicutes,24C32@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02035	515620.EUBELI_01800	9.45e-06	47.4	2C7T4@1|root,34BKT@2|Bacteria,1W01U@1239|Firmicutes,252VI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02036	742765.HMPREF9457_02499	1.92e-240	660.0	COG0358@1|root,COG0358@2|Bacteria,1TQTJ@1239|Firmicutes,25C9F@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3991,Toprim_2
KFPFDFKC_02037	500632.CLONEX_00568	3.04e-128	364.0	COG2003@1|root,COG2003@2|Bacteria,1V38E@1239|Firmicutes,24M00@186801|Clostridia	186801|Clostridia	L	DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	RadC
KFPFDFKC_02038	742765.HMPREF9457_02501	5.09e-17	72.4	28RBS@1|root,2ZDRA@2|Bacteria,1W5FZ@1239|Firmicutes,25535@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02039	500632.CLONEX_00567	8.68e-231	636.0	28PM6@1|root,2Z8J4@2|Bacteria,1UXZE@1239|Firmicutes,24B7N@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02040	742765.HMPREF9457_02503	0.0	3360.0	COG4932@1|root,COG4932@2|Bacteria,1TRG6@1239|Firmicutes,2492K@186801|Clostridia,27V8U@189330|Dorea	186801|Clostridia	M	Cna protein B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	Gram_pos_anchor
KFPFDFKC_02041	742765.HMPREF9457_02504	5.92e-146	418.0	28MV0@1|root,2ZB2P@2|Bacteria,1TSBN@1239|Firmicutes,24F9H@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02042	483218.BACPEC_03136	6.66e-11	58.5	2CF7V@1|root,337Q1@2|Bacteria,1VJMP@1239|Firmicutes,24TS8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02043	483218.BACPEC_03135	2.63e-96	281.0	2AG7F@1|root,316CH@2|Bacteria,1UZTU@1239|Firmicutes,24EJ0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02044	742765.HMPREF9457_02507	6.34e-217	599.0	2DBA0@1|root,2Z80J@2|Bacteria,1TQY3@1239|Firmicutes,24B0S@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K18640	-	-	-	-	ko00000,ko04812	-	-	-	StbA
KFPFDFKC_02045	483218.BACPEC_03134	1.89e-15	75.9	2DBA0@1|root,2Z80J@2|Bacteria,1TQY3@1239|Firmicutes,24B0S@186801|Clostridia,268A8@186813|unclassified Clostridiales	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K18640	-	-	-	-	ko00000,ko04812	-	-	-	StbA
KFPFDFKC_02047	483218.BACPEC_03132	1.26e-112	323.0	COG1396@1|root,COG1396@2|Bacteria,1UZN9@1239|Firmicutes,24APP@186801|Clostridia,26C4F@186813|unclassified Clostridiales	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
KFPFDFKC_02048	457412.RSAG_00549	7.39e-296	806.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,3WN2H@541000|Ruminococcaceae	186801|Clostridia	L	DNA binding domain of tn916 integrase	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_integrase
KFPFDFKC_02049	1121115.AXVN01000053_gene1849	6.55e-44	142.0	2CCB2@1|root,32W5T@2|Bacteria,1VDNT@1239|Firmicutes,24QFS@186801|Clostridia,3Y0EU@572511|Blautia	186801|Clostridia	S	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
KFPFDFKC_02050	1121115.AXVN01000053_gene1848	9.49e-198	547.0	COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,248F0@186801|Clostridia,3XYTT@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
KFPFDFKC_02051	411459.RUMOBE_00671	5.89e-115	330.0	COG1846@1|root,COG1846@2|Bacteria,1UK34@1239|Firmicutes,24Y1H@186801|Clostridia,3XZJB@572511|Blautia	186801|Clostridia	K	COG NOG16925 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	RepA_N
KFPFDFKC_02052	1163671.JAGI01000001_gene369	2.46e-22	95.9	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,24AG9@186801|Clostridia,36GYN@31979|Clostridiaceae	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
KFPFDFKC_02053	1256908.HMPREF0373_00979	1e-225	624.0	COG5002@1|root,COG5002@2|Bacteria,1UI6U@1239|Firmicutes,25H6P@186801|Clostridia	186801|Clostridia	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
KFPFDFKC_02054	1256908.HMPREF0373_00978	8.1e-148	417.0	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,249TG@186801|Clostridia,25V3T@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
KFPFDFKC_02055	1256908.HMPREF0373_00977	0.0	1274.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia,25V5H@186806|Eubacteriaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
KFPFDFKC_02056	1256908.HMPREF0373_00976	1.64e-171	480.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,25V99@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
KFPFDFKC_02057	742733.HMPREF9469_05559	2.49e-172	493.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,21Z66@1506553|Lachnoclostridium	186801|Clostridia	L	COG COG4974 Site-specific recombinase XerD	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_integrase
KFPFDFKC_02058	411467.BACCAP_04675	2.94e-24	92.8	2CCB2@1|root,32S7G@2|Bacteria,1VABI@1239|Firmicutes,24MZT@186801|Clostridia,269TP@186813|unclassified Clostridiales	186801|Clostridia	S	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
KFPFDFKC_02059	428127.EUBDOL_00353	1.64e-113	348.0	COG0732@1|root,COG0732@2|Bacteria,1TT1D@1239|Firmicutes,3VRTN@526524|Erysipelotrichia	526524|Erysipelotrichia	V	Type I restriction	-	-	-	-	-	-	-	-	-	-	-	-	Methylase_S
KFPFDFKC_02060	511680.BUTYVIB_01044	5.12e-176	492.0	COG0582@1|root,COG0582@2|Bacteria,1UJT9@1239|Firmicutes,24EEC@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
KFPFDFKC_02061	869209.Tresu_1113	6.14e-86	276.0	COG0732@1|root,COG0732@2|Bacteria,2J5QW@203691|Spirochaetes	203691|Spirochaetes	V	type I restriction	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
KFPFDFKC_02062	1378168.N510_01743	1.04e-38	142.0	COG0732@1|root,COG0732@2|Bacteria,1TT1D@1239|Firmicutes	1239|Firmicutes	V	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
KFPFDFKC_02063	511680.BUTYVIB_01047	4.59e-276	763.0	COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,247RY@186801|Clostridia,4BYIZ@830|Butyrivibrio	186801|Clostridia	V	HsdM N-terminal domain	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,Methylase_S,N6_Mtase
KFPFDFKC_02064	1235793.C809_00406	0.0	1427.0	COG4096@1|root,COG4096@2|Bacteria,1UI7V@1239|Firmicutes,25ED3@186801|Clostridia,27IP4@186928|unclassified Lachnospiraceae	186801|Clostridia	L	EcoEI R protein C-terminal	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF4145,EcoEI_R_C,HSDR_N,HSDR_N_2,Helicase_C,ResIII
KFPFDFKC_02066	1089455.MOPEL_098_00650	4.71e-98	315.0	COG1195@1|root,COG3593@1|root,COG1195@2|Bacteria,COG3593@2|Bacteria,2I6SR@201174|Actinobacteria	201174|Actinobacteria	L	DNA synthesis involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02067	658086.HMPREF0994_00357	5.08e-154	437.0	COG2253@1|root,COG2253@2|Bacteria,1TSFX@1239|Firmicutes,24C3A@186801|Clostridia,27MX9@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
KFPFDFKC_02068	658086.HMPREF0994_00358	4.88e-103	301.0	COG5340@1|root,COG5340@2|Bacteria,1TQSK@1239|Firmicutes,247JC@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
KFPFDFKC_02072	585394.RHOM_00105	9.32e-179	505.0	COG0673@1|root,COG0673@2|Bacteria,1TPT5@1239|Firmicutes,248MV@186801|Clostridia	186801|Clostridia	E	Oxidoreductase NAD-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
KFPFDFKC_02075	622312.ROSEINA2194_03243	3.18e-119	342.0	COG1838@1|root,COG1838@2|Bacteria,1V1CP@1239|Firmicutes,24FRK@186801|Clostridia	186801|Clostridia	C	Fe-S type, tartrate fumarate subfamily, beta	fumB	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
KFPFDFKC_02076	585394.RHOM_00065	7.92e-170	478.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia	186801|Clostridia	C	Fe-S type, tartrate fumarate subfamily, alpha	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
KFPFDFKC_02077	622312.ROSEINA2194_03241	8.65e-128	377.0	COG0840@1|root,COG4905@1|root,COG0840@2|Bacteria,COG4905@2|Bacteria,1V2HX@1239|Firmicutes,24B3D@186801|Clostridia	186801|Clostridia	D	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
KFPFDFKC_02078	585394.RHOM_00055	1.39e-68	209.0	COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,24JVN@186801|Clostridia	186801|Clostridia	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
KFPFDFKC_02079	585394.RHOM_00050	8.21e-170	478.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
KFPFDFKC_02080	585394.RHOM_00045	8.11e-176	492.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
KFPFDFKC_02081	585394.RHOM_00040	1.84e-110	328.0	COG5495@1|root,COG5495@2|Bacteria,1UZZU@1239|Firmicutes,249YF@186801|Clostridia	186801|Clostridia	S	NADP oxidoreductase coenzyme F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
KFPFDFKC_02082	658086.HMPREF0994_06595	0.0	1187.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,27JWP@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	CBM_6,Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
KFPFDFKC_02083	742740.HMPREF9474_01564	7.2e-53	171.0	2AH77@1|root,317H3@2|Bacteria,1V6I2@1239|Firmicutes,24KDW@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3021)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3021
KFPFDFKC_02084	1123075.AUDP01000012_gene3562	8.46e-53	171.0	COG3279@1|root,COG3279@2|Bacteria,1VEPW@1239|Firmicutes,24K2U@186801|Clostridia	186801|Clostridia	K	LytTr DNA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
KFPFDFKC_02085	1280692.AUJL01000002_gene2728	7.45e-89	290.0	COG1132@1|root,COG1132@2|Bacteria,1V2WX@1239|Firmicutes,24GV7@186801|Clostridia,36R7T@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
KFPFDFKC_02086	202954.BBNK01000014_gene2895	2.17e-12	75.1	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,3NJR0@468|Moraxellaceae	1236|Gammaproteobacteria	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
KFPFDFKC_02087	1211817.CCAT010000014_gene1390	1.06e-25	115.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,36E8H@31979|Clostridiaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,NUDIX,PqqD,Radical_SAM,SPASM
KFPFDFKC_02089	397291.C804_00162	1.87e-57	194.0	COG1396@1|root,COG1396@2|Bacteria,1VC2K@1239|Firmicutes,24NMY@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
KFPFDFKC_02090	397291.C804_00163	3.21e-37	142.0	2DY23@1|root,347RM@2|Bacteria,1VQMX@1239|Firmicutes,24UP2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02091	537007.BLAHAN_05724	3.01e-158	455.0	COG3550@1|root,COG3550@2|Bacteria,1UYFT@1239|Firmicutes,24C8G@186801|Clostridia,3Y2EV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02092	585394.RHOM_00030	0.0	1509.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
KFPFDFKC_02093	585394.RHOM_00025	0.0	1207.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
KFPFDFKC_02094	622312.ROSEINA2194_03238	3.05e-214	597.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
KFPFDFKC_02095	585394.RHOM_00015	1.54e-34	119.0	COG2501@1|root,COG2501@2|Bacteria	2|Bacteria	S	S4 domain	yaaA	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
KFPFDFKC_02096	585394.RHOM_00010	3.22e-248	683.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,248EG@186801|Clostridia	186801|Clostridia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
KFPFDFKC_02097	622312.ROSEINA2194_03235	2.31e-296	812.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
KFPFDFKC_02098	585394.RHOM_16930	3.25e-20	80.9	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,24UGN@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
KFPFDFKC_02099	585394.RHOM_16925	3.33e-65	199.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,24QK5@186801|Clostridia	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
KFPFDFKC_02100	585394.RHOM_16915	1.01e-218	614.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia	186801|Clostridia	U	Membrane protein insertase, YidC Oxa1 family	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
KFPFDFKC_02101	622312.ROSEINA2194_03230	1.05e-118	342.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia	186801|Clostridia	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
KFPFDFKC_02102	622312.ROSEINA2194_03229	1.17e-271	750.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,248A9@186801|Clostridia	186801|Clostridia	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
KFPFDFKC_02103	622312.ROSEINA2194_03228	0.0	1118.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,247U2@186801|Clostridia	186801|Clostridia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
KFPFDFKC_02104	585394.RHOM_16890	2.79e-127	367.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia	186801|Clostridia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
KFPFDFKC_02105	585394.RHOM_16885	2.74e-155	444.0	COG0596@1|root,COG0596@2|Bacteria,1TR3M@1239|Firmicutes,24DR9@186801|Clostridia	186801|Clostridia	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
KFPFDFKC_02106	585394.RHOM_16880	1.56e-109	329.0	COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia	186801|Clostridia	T	Histidine kinase	degS	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegS,HATPase_c,HisKA_3
KFPFDFKC_02107	585394.RHOM_16875	7.92e-109	318.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,24FZX@186801|Clostridia	186801|Clostridia	K	response regulator receiver	degU	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
KFPFDFKC_02108	585394.RHOM_16870	7.63e-168	470.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
KFPFDFKC_02109	585394.RHOM_16865	6.14e-152	434.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
KFPFDFKC_02110	585394.RHOM_16860	6.07e-62	196.0	COG1196@1|root,COG1196@2|Bacteria,1VAV4@1239|Firmicutes,24NPU@186801|Clostridia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
KFPFDFKC_02111	585394.RHOM_16855	6.94e-144	417.0	COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,248S5@186801|Clostridia	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
KFPFDFKC_02112	585394.RHOM_16850	5.1e-146	418.0	28J5A@1|root,2Z916@2|Bacteria,1TSGX@1239|Firmicutes,24AZU@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3881
KFPFDFKC_02113	411459.RUMOBE_02158	8.98e-18	82.4	29YMG@1|root,30KGY@2|Bacteria,1V4T3@1239|Firmicutes,24I7T@186801|Clostridia,3Y0BR@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
KFPFDFKC_02114	1121115.AXVN01000199_gene606	1.45e-241	665.0	COG3177@1|root,COG3177@2|Bacteria,1TQMC@1239|Firmicutes,248JU@186801|Clostridia,3XYYW@572511|Blautia	186801|Clostridia	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
KFPFDFKC_02116	511680.BUTYVIB_00703	9.47e-137	394.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia,4BX3E@830|Butyrivibrio	186801|Clostridia	K	ParB-like nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
KFPFDFKC_02117	511680.BUTYVIB_00702	4.28e-108	320.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,247R1@186801|Clostridia,4BWG0@830|Butyrivibrio	186801|Clostridia	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
KFPFDFKC_02118	877421.AUJT01000007_gene695	2.36e-23	112.0	COG1033@1|root,COG1033@2|Bacteria,1VHSF@1239|Firmicutes,24R7H@186801|Clostridia,27PM0@186928|unclassified Lachnospiraceae	186801|Clostridia	S	YARHG	-	-	-	-	-	-	-	-	-	-	-	-	YARHG,zinc_ribbon_2
KFPFDFKC_02119	411459.RUMOBE_02234	3.98e-29	107.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia	186801|Clostridia	K	Belongs to the ParB family	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
KFPFDFKC_02120	511680.BUTYVIB_00634	1.2e-11	64.3	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,4BZJF@830|Butyrivibrio	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
KFPFDFKC_02121	511680.BUTYVIB_00633	8.85e-45	145.0	2F6CB@1|root,33YVQ@2|Bacteria,1VWV0@1239|Firmicutes,2523Z@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02122	622312.ROSEINA2194_00408	1.64e-287	808.0	COG3119@1|root,COG3119@2|Bacteria,1TSGV@1239|Firmicutes,24C61@186801|Clostridia	186801|Clostridia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
KFPFDFKC_02123	515620.EUBELI_20482	3.91e-263	733.0	COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,2482K@186801|Clostridia,25V4W@186806|Eubacteriaceae	186801|Clostridia	U	BCCT, betaine/carnitine/choline family transporter	caiT	-	-	ko:K03451,ko:K05245	-	-	-	-	ko00000,ko02000	2.A.15,2.A.15.2	-	-	BCCT
KFPFDFKC_02124	515620.EUBELI_20483	8.37e-124	358.0	COG4750@1|root,COG4750@2|Bacteria,1UYW1@1239|Firmicutes,25CE0@186801|Clostridia,25Y7D@186806|Eubacteriaceae	186801|Clostridia	M	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	APH,HTH_24,NTP_transf_3,NTP_transferase
KFPFDFKC_02125	511680.BUTYVIB_02107	1.16e-118	360.0	COG0510@1|root,COG4750@1|root,COG0510@2|Bacteria,COG4750@2|Bacteria,1TRCJ@1239|Firmicutes,24BS7@186801|Clostridia,4C27S@830|Butyrivibrio	186801|Clostridia	M	Choline/ethanolamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Choline_kinase,HTH_24,NTP_transf_3,NTP_transferase
KFPFDFKC_02126	397288.C806_02740	9.28e-197	577.0	COG3119@1|root,COG3119@2|Bacteria,1TSGV@1239|Firmicutes,24C61@186801|Clostridia	186801|Clostridia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
KFPFDFKC_02127	515620.EUBELI_00272	8.19e-156	446.0	COG3475@1|root,COG3475@2|Bacteria,1V8MH@1239|Firmicutes,24MDQ@186801|Clostridia	186801|Clostridia	M	LicD family	-	-	-	ko:K07271	-	-	-	-	ko00000,ko01000	-	-	-	LicD
KFPFDFKC_02128	478749.BRYFOR_09296	6.66e-277	769.0	COG4974@1|root,COG4974@2|Bacteria,1TQST@1239|Firmicutes,247YT@186801|Clostridia	186801|Clostridia	L	PFAM transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
KFPFDFKC_02130	742735.HMPREF9467_05194	2.34e-74	223.0	COG3436@1|root,COG3436@2|Bacteria,1V7U9@1239|Firmicutes,24K4W@186801|Clostridia	186801|Clostridia	L	PFAM IS66 Orf2	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
KFPFDFKC_02132	585394.RHOM_00785	2.39e-28	110.0	COG2089@1|root,COG2089@2|Bacteria,1TS09@1239|Firmicutes,249DN@186801|Clostridia	186801|Clostridia	M	synthase	pseI	-	2.5.1.56,2.5.1.97	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R09841	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
KFPFDFKC_02133	622312.ROSEINA2194_00417	7.73e-129	375.0	COG3955@1|root,COG3955@2|Bacteria,1VEC3@1239|Firmicutes,24P4A@186801|Clostridia	186801|Clostridia	M	Domain of unknown function (DUF1919)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1919
KFPFDFKC_02134	585394.RHOM_00795	1.83e-144	424.0	COG1216@1|root,COG1216@2|Bacteria,1V5UZ@1239|Firmicutes,24J2K@186801|Clostridia	186801|Clostridia	S	Glycosyltransferase like family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_5
KFPFDFKC_02135	622312.ROSEINA2194_00397	6.21e-301	839.0	COG1887@1|root,COG1887@2|Bacteria,1UY3V@1239|Firmicutes,24FED@186801|Clostridia	186801|Clostridia	M	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
KFPFDFKC_02136	622312.ROSEINA2194_02511	1.35e-235	657.0	COG0615@1|root,COG2513@1|root,COG0615@2|Bacteria,COG2513@2|Bacteria,1TQVY@1239|Firmicutes,24AC5@186801|Clostridia	186801|Clostridia	GM	phosphoenolpyruvate	aepX	-	5.4.2.9	ko:K01841	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	-	R00661	RC02792	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like,NTP_transf_3,PEP_mutase
KFPFDFKC_02137	1280692.AUJL01000001_gene306	2.02e-149	434.0	COG0028@1|root,COG0028@2|Bacteria,1TSJZ@1239|Firmicutes,24AIU@186801|Clostridia,36F1Y@31979|Clostridiaceae	186801|Clostridia	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	aepY	-	4.1.1.82	ko:K09459	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	-	R04053	RC00506	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
KFPFDFKC_02138	397287.C807_02814	4.53e-102	303.0	COG4750@1|root,COG4750@2|Bacteria,1UYW1@1239|Firmicutes,25CE0@186801|Clostridia,27M9E@186928|unclassified Lachnospiraceae	186801|Clostridia	M	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	APH,HTH_24,NTP_transf_3,NTP_transferase
KFPFDFKC_02139	397287.C807_02815	2.83e-175	496.0	COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,24919@186801|Clostridia,27IRA@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily	phnW	-	2.6.1.37,3.11.1.1	ko:K03430,ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	-	R00747,R04152	RC00008,RC00062,RC00368	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_5,HAD_2
KFPFDFKC_02140	397287.C807_02815	1.81e-19	86.3	COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,24919@186801|Clostridia,27IRA@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily	phnW	-	2.6.1.37,3.11.1.1	ko:K03430,ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	-	R00747,R04152	RC00008,RC00062,RC00368	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_5,HAD_2
KFPFDFKC_02141	1235802.C823_01269	1.77e-129	370.0	COG1213@1|root,COG1213@2|Bacteria,1V42C@1239|Firmicutes,24HN4@186801|Clostridia	186801|Clostridia	M	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
KFPFDFKC_02142	1235802.C823_01271	7.22e-112	324.0	COG0560@1|root,COG0560@2|Bacteria,1V53G@1239|Firmicutes,24I7S@186801|Clostridia	186801|Clostridia	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
KFPFDFKC_02143	1235802.C823_01272	9.35e-91	274.0	COG1794@1|root,COG1794@2|Bacteria,1TR3U@1239|Firmicutes,24ADY@186801|Clostridia,25X0D@186806|Eubacteriaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
KFPFDFKC_02144	1235802.C823_01275	6.56e-41	142.0	COG0500@1|root,COG0500@2|Bacteria,1UP91@1239|Firmicutes,25H94@186801|Clostridia	186801|Clostridia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02145	1235802.C823_01275	3.24e-51	169.0	COG0500@1|root,COG0500@2|Bacteria,1UP91@1239|Firmicutes,25H94@186801|Clostridia	186801|Clostridia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02146	1235802.C823_01270	4.85e-166	472.0	COG0535@1|root,COG0535@2|Bacteria,1V348@1239|Firmicutes,24GVU@186801|Clostridia,25X0M@186806|Eubacteriaceae	186801|Clostridia	C	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
KFPFDFKC_02147	1235802.C823_01266	2.03e-81	270.0	COG1887@1|root,COG1887@2|Bacteria,1UGR4@1239|Firmicutes,24F3S@186801|Clostridia,25YIM@186806|Eubacteriaceae	186801|Clostridia	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
KFPFDFKC_02148	622312.ROSEINA2194_00398	2.11e-177	505.0	COG4641@1|root,COG4641@2|Bacteria,1V3QP@1239|Firmicutes,24I06@186801|Clostridia	186801|Clostridia	S	DUF based on E. rectale Gene description (DUF3880)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3880,Glyco_trans_1_2
KFPFDFKC_02149	585394.RHOM_00800	5.26e-242	668.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	pseC	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
KFPFDFKC_02150	585394.RHOM_00790	5.05e-112	337.0	COG3980@1|root,COG3980@2|Bacteria,1U2ZW@1239|Firmicutes,24HWM@186801|Clostridia	186801|Clostridia	M	pseudaminic acid biosynthesis-associated protein PseG	pseG	-	3.6.1.57	ko:K15897	ko00520,map00520	-	R09834	RC00005,RC00078	ko00000,ko00001,ko01000	-	-	-	Glyco_tran_28_C
KFPFDFKC_02151	585394.RHOM_00785	7.22e-220	609.0	COG2089@1|root,COG2089@2|Bacteria,1TS09@1239|Firmicutes,249DN@186801|Clostridia	186801|Clostridia	M	synthase	pseI	-	2.5.1.56,2.5.1.97	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R09841	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
KFPFDFKC_02152	585394.RHOM_00775	3.59e-37	154.0	COG1670@1|root,COG2755@1|root,COG1670@2|Bacteria,COG2755@2|Bacteria,1UQGP@1239|Firmicutes,24EU7@186801|Clostridia	186801|Clostridia	E	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02153	585394.RHOM_00715	7.36e-177	515.0	COG0438@1|root,COG0438@2|Bacteria,1V5AP@1239|Firmicutes,24GJ0@186801|Clostridia	186801|Clostridia	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
KFPFDFKC_02154	585394.RHOM_00820	5.13e-144	412.0	COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia	186801|Clostridia	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
KFPFDFKC_02155	1235802.C823_01279	2.6e-73	248.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1V5FQ@1239|Firmicutes,24HV0@186801|Clostridia,25XR8@186806|Eubacteriaceae	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_5,Glycos_transf_2
KFPFDFKC_02156	622312.ROSEINA2194_00402	5.24e-122	353.0	COG1083@1|root,COG1083@2|Bacteria,1UFAT@1239|Firmicutes,24G5I@186801|Clostridia	186801|Clostridia	M	Cytidylyltransferase	neuA	-	2.7.7.82	ko:K18431	ko00520,map00520	-	R10182	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3
KFPFDFKC_02157	622312.ROSEINA2194_00401	1.27e-115	336.0	COG1442@1|root,COG1442@2|Bacteria,1U6EG@1239|Firmicutes,24B83@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4422,Glyco_transf_8
KFPFDFKC_02158	622312.ROSEINA2194_00400	4.9e-56	180.0	28Z9X@1|root,2ZM1S@2|Bacteria,1W414@1239|Firmicutes,256AY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02159	622312.ROSEINA2194_00399	0.0	885.0	COG2242@1|root,COG2242@2|Bacteria,1UKUE@1239|Firmicutes,25G43@186801|Clostridia	186801|Clostridia	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
KFPFDFKC_02160	622312.ROSEINA2194_00397	3.33e-309	860.0	COG1887@1|root,COG1887@2|Bacteria,1UY3V@1239|Firmicutes,24FED@186801|Clostridia	186801|Clostridia	M	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
KFPFDFKC_02161	622312.ROSEINA2194_00395	3.23e-57	181.0	2C12Y@1|root,32STC@2|Bacteria,1VCPE@1239|Firmicutes,24Q1P@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02162	622312.ROSEINA2194_00394	7.61e-275	764.0	COG4641@1|root,COG4641@2|Bacteria,1UMWB@1239|Firmicutes,24CQX@186801|Clostridia	186801|Clostridia	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
KFPFDFKC_02163	622312.ROSEINA2194_00393	4.89e-161	453.0	COG0107@1|root,COG0107@2|Bacteria,1VRBC@1239|Firmicutes,24Y72@186801|Clostridia	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	-	-	-	-	-	-	-	-	-	-	-	-	His_biosynth
KFPFDFKC_02164	585394.RHOM_00705	4.9e-119	343.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
KFPFDFKC_02165	585394.RHOM_00700	2.22e-280	766.0	COG0037@1|root,COG0037@2|Bacteria,1V1S0@1239|Firmicutes,24BSC@186801|Clostridia	186801|Clostridia	D	tRNA processing	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02166	622312.ROSEINA2194_00389	1.73e-232	640.0	COG1086@1|root,COG1086@2|Bacteria,1TPTC@1239|Firmicutes,247YC@186801|Clostridia	186801|Clostridia	M	Polysaccharide biosynthesis protein	pseB	-	4.2.1.115	ko:K15894	ko00520,map00520	-	R09697	RC02609	ko00000,ko00001,ko01000	-	-	-	Polysacc_synt_2
KFPFDFKC_02167	622312.ROSEINA2194_00388	1.07e-212	595.0	COG4641@1|root,COG4641@2|Bacteria,1TS28@1239|Firmicutes,24E2J@186801|Clostridia	186801|Clostridia	S	DUF based on E. rectale Gene description (DUF3880)	-	-	-	ko:K06320	-	-	-	-	ko00000	-	-	-	DUF3880,Glyco_trans_1_2
KFPFDFKC_02168	622312.ROSEINA2194_00387	5.4e-221	616.0	COG4641@1|root,COG4641@2|Bacteria,1TR7G@1239|Firmicutes,249U5@186801|Clostridia	186801|Clostridia	P	DUF based on E. rectale Gene description (DUF3880)	-	-	-	ko:K06320	-	-	-	-	ko00000	-	-	-	DUF3880,Glyco_trans_1_2
KFPFDFKC_02169	585394.RHOM_00980	0.0	2358.0	COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
KFPFDFKC_02170	585394.RHOM_00985	0.0	2254.0	COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
KFPFDFKC_02171	585394.RHOM_01010	5.46e-89	261.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia	186801|Clostridia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
KFPFDFKC_02172	585394.RHOM_01020	7.42e-102	295.0	COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,24FQN@186801|Clostridia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
KFPFDFKC_02173	585394.RHOM_01025	0.0	1373.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia	186801|Clostridia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
KFPFDFKC_02174	585394.RHOM_01030	1.86e-287	785.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
KFPFDFKC_02175	411474.COPEUT_00477	2.56e-125	368.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,247X1@186801|Clostridia	186801|Clostridia	EG	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	EamA
KFPFDFKC_02176	411474.COPEUT_02349	1.4e-103	310.0	COG3868@1|root,COG3868@2|Bacteria,1V4J5@1239|Firmicutes,24GI7@186801|Clostridia	186801|Clostridia	M	Glycoside-hydrolase family GH114	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_114
KFPFDFKC_02177	397291.C804_00046	2.5e-123	365.0	COG1266@1|root,COG1266@2|Bacteria,1UYS2@1239|Firmicutes,24BKW@186801|Clostridia,27KG8@186928|unclassified Lachnospiraceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
KFPFDFKC_02178	585394.RHOM_14795	4.8e-20	80.9	2DRBT@1|root,33B4Z@2|Bacteria,1VMZQ@1239|Firmicutes,24UIT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02179	622312.ROSEINA2194_02025	1.85e-148	431.0	COG4677@1|root,COG4677@2|Bacteria,1UYI6@1239|Firmicutes,24B29@186801|Clostridia	186801|Clostridia	G	Pectinesterase	-	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Pectinesterase
KFPFDFKC_02180	33035.JPJF01000028_gene2808	1.69e-126	364.0	COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,248NY@186801|Clostridia,3XZRB@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	fucA	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
KFPFDFKC_02181	585394.RHOM_14780	0.0	1229.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	glgX	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
KFPFDFKC_02182	585394.RHOM_14775	2.08e-130	375.0	COG1028@1|root,COG1028@2|Bacteria,1TZY6@1239|Firmicutes,248QZ@186801|Clostridia	186801|Clostridia	IQ	Oxidoreductase, short chain dehydrogenase reductase family protein	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
KFPFDFKC_02183	1280688.AUJB01000010_gene2801	1.22e-45	159.0	COG0507@1|root,COG0507@2|Bacteria,1VAZW@1239|Firmicutes,24NP3@186801|Clostridia,3NI77@46205|Pseudobutyrivibrio	186801|Clostridia	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02185	585394.RHOM_06725	1.25e-195	577.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
KFPFDFKC_02186	622312.ROSEINA2194_02031	4.8e-158	444.0	COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,24DII@186801|Clostridia	186801|Clostridia	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
KFPFDFKC_02187	585394.RHOM_14750	7.73e-93	280.0	2AYHW@1|root,31QMC@2|Bacteria,1V6S7@1239|Firmicutes,24NBV@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	TraX
KFPFDFKC_02188	1235799.C818_03344	1.12e-103	311.0	COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,248AC@186801|Clostridia,27IRB@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
KFPFDFKC_02189	411468.CLOSCI_03983	2.85e-92	276.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,24DG3@186801|Clostridia,21ZN5@1506553|Lachnoclostridium	186801|Clostridia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
KFPFDFKC_02190	720554.Clocl_3524	1.31e-70	222.0	COG0637@1|root,COG0637@2|Bacteria,1V1DF@1239|Firmicutes,24DES@186801|Clostridia,3WS73@541000|Ruminococcaceae	186801|Clostridia	S	IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
KFPFDFKC_02191	585394.RHOM_14715	2.1e-82	248.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,24IB5@186801|Clostridia	186801|Clostridia	M	Acetyltransferase GNAT family	yncA	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
KFPFDFKC_02192	585394.RHOM_14710	7.89e-186	521.0	COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,24956@186801|Clostridia	186801|Clostridia	P	Mg2 transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
KFPFDFKC_02193	1256908.HMPREF0373_01077	9.73e-194	538.0	COG1092@1|root,COG1092@2|Bacteria,1TPUD@1239|Firmicutes,2480X@186801|Clostridia,25VPS@186806|Eubacteriaceae	186801|Clostridia	H	S-adenosylmethionine-dependent methyltransferase	rlmL_1	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
KFPFDFKC_02194	585394.RHOM_14635	1.22e-261	726.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia	186801|Clostridia	P	Cation transport protein	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
KFPFDFKC_02195	585394.RHOM_14630	3.92e-279	768.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia	186801|Clostridia	P	domain protein	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
KFPFDFKC_02196	585394.RHOM_14620	3.22e-65	199.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia	186801|Clostridia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
KFPFDFKC_02197	622312.ROSEINA2194_02051	9.66e-151	425.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
KFPFDFKC_02198	622312.ROSEINA2194_02052	1.43e-128	367.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
KFPFDFKC_02199	585394.RHOM_14605	1.07e-58	182.0	COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,24MN8@186801|Clostridia	186801|Clostridia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
KFPFDFKC_02200	585394.RHOM_14600	3.56e-198	549.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
KFPFDFKC_02201	622312.ROSEINA2194_02055	4.17e-60	185.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,24JN3@186801|Clostridia	186801|Clostridia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
KFPFDFKC_02202	622312.ROSEINA2194_02056	7.16e-82	243.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia	186801|Clostridia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
KFPFDFKC_02203	585394.RHOM_14585	1.69e-151	426.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia	186801|Clostridia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
KFPFDFKC_02204	622312.ROSEINA2194_02058	2.11e-98	286.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
KFPFDFKC_02205	585394.RHOM_14575	5.47e-34	117.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia	186801|Clostridia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
KFPFDFKC_02206	622312.ROSEINA2194_02060	3.48e-53	167.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
KFPFDFKC_02207	585394.RHOM_14565	2.87e-76	228.0	COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,24H98@186801|Clostridia	186801|Clostridia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
KFPFDFKC_02208	1235790.C805_00242	7.38e-61	187.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,25WQ0@186806|Eubacteriaceae	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
KFPFDFKC_02209	585394.RHOM_14555	9.01e-121	345.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
KFPFDFKC_02210	585394.RHOM_14550	4.1e-39	129.0	COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,24QR1@186801|Clostridia	186801|Clostridia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
KFPFDFKC_02211	585394.RHOM_14545	2.87e-88	259.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
KFPFDFKC_02212	585394.RHOM_14535	7.41e-120	343.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,2496R@186801|Clostridia	186801|Clostridia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
KFPFDFKC_02213	622312.ROSEINA2194_02066	6.5e-73	219.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
KFPFDFKC_02214	585394.RHOM_14525	1.84e-106	308.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
KFPFDFKC_02215	585394.RHOM_14520	3.04e-32	112.0	COG1841@1|root,COG1841@2|Bacteria	2|Bacteria	J	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	rpmD	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
KFPFDFKC_02216	622312.ROSEINA2194_02069	1.42e-92	271.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
KFPFDFKC_02217	585394.RHOM_14510	3.47e-276	760.0	COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,248T9@186801|Clostridia	186801|Clostridia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
KFPFDFKC_02218	622312.ROSEINA2194_02071	1.63e-147	416.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
KFPFDFKC_02219	585394.RHOM_14500	2.38e-154	437.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia	186801|Clostridia	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
KFPFDFKC_02220	397288.C806_00699	1.21e-18	80.1	COG2163@1|root,COG2163@2|Bacteria,1VEPA@1239|Firmicutes,24UP0@186801|Clostridia	186801|Clostridia	J	COG2163 Ribosomal protein L14E L6E L27E	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02221	585394.RHOM_14490	6.91e-45	145.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
KFPFDFKC_02222	585394.RHOM_14475	3.76e-72	218.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
KFPFDFKC_02223	622312.ROSEINA2194_02078	1.22e-74	224.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia	186801|Clostridia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
KFPFDFKC_02224	585394.RHOM_14465	1.58e-132	376.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
KFPFDFKC_02225	585394.RHOM_14460	8.48e-216	597.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
KFPFDFKC_02226	585394.RHOM_14450	9.26e-109	315.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,24J9T@186801|Clostridia	186801|Clostridia	J	ribosomal protein l17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
KFPFDFKC_02227	1069534.LRC_05120	5.88e-87	259.0	COG4283@1|root,COG4283@2|Bacteria,1V8M5@1239|Firmicutes,4HHMT@91061|Bacilli,3F6RT@33958|Lactobacillaceae	91061|Bacilli	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF1706
KFPFDFKC_02228	1408311.JNJM01000002_gene1192	1.34e-76	229.0	29A02@1|root,2ZX1N@2|Bacteria,1V48B@1239|Firmicutes,24HF1@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02229	469596.HMPREF9488_01772	8.48e-57	177.0	COG3070@1|root,COG3070@2|Bacteria,1V42M@1239|Firmicutes,3VQTW@526524|Erysipelotrichia	526524|Erysipelotrichia	K	TfoX N-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
KFPFDFKC_02230	1235798.C817_01435	1.74e-42	145.0	2EAJ6@1|root,334N3@2|Bacteria,1VFXU@1239|Firmicutes,24RPH@186801|Clostridia	186801|Clostridia	S	Toxin ToxN, type III toxin-antitoxin system	-	-	-	ko:K19167	-	-	-	-	ko00000,ko02048	-	-	-	ToxN_toxin
KFPFDFKC_02231	585394.RHOM_01065	6.72e-274	757.0	COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
KFPFDFKC_02232	622312.ROSEINA2194_02099	7.05e-154	433.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia	186801|Clostridia	T	response regulator receiver	srrA_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
KFPFDFKC_02233	585394.RHOM_01075	0.0	1191.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
KFPFDFKC_02234	585394.RHOM_01080	5.04e-178	514.0	COG0265@1|root,COG0265@2|Bacteria,1TTAZ@1239|Firmicutes,24BWH@186801|Clostridia	186801|Clostridia	O	PDZ DHR GLGF domain protein	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
KFPFDFKC_02235	585394.RHOM_01085	1.8e-202	563.0	COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,248SS@186801|Clostridia	186801|Clostridia	S	domain protein	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
KFPFDFKC_02236	585394.RHOM_01090	1.35e-272	754.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
KFPFDFKC_02238	1235798.C817_03166	8.87e-71	217.0	2CUHA@1|root,33IHG@2|Bacteria,1VPC1@1239|Firmicutes,24W2W@186801|Clostridia,27WQP@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02239	1235792.C808_02239	1.86e-20	82.4	2C7EF@1|root,33FU0@2|Bacteria,1VMPB@1239|Firmicutes,25PQ4@186801|Clostridia,27QDU@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02240	97139.C824_04207	1.38e-160	452.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,247R1@186801|Clostridia,36H17@31979|Clostridiaceae	186801|Clostridia	D	Cellulose biosynthesis protein BcsQ	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
KFPFDFKC_02241	500632.CLONEX_00690	1.94e-140	405.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia	186801|Clostridia	K	Belongs to the ParB family	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
KFPFDFKC_02242	1235792.C808_02242	6.87e-132	388.0	2DBC6@1|root,2Z8BZ@2|Bacteria,1TQXM@1239|Firmicutes,2484N@186801|Clostridia,27K2K@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Replication initiator protein A (RepA) N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	RepA_N
KFPFDFKC_02243	1235792.C808_02243	2.07e-43	145.0	2BAQE@1|root,3245B@2|Bacteria,1V86A@1239|Firmicutes,24MCZ@186801|Clostridia,27PSB@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02244	1235792.C808_02244	2.34e-36	127.0	COG1476@1|root,COG1476@2|Bacteria,1VK4C@1239|Firmicutes,24KVF@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
KFPFDFKC_02245	411459.RUMOBE_02241	1.11e-08	52.8	2FJSN@1|root,34BFD@2|Bacteria,1W0X9@1239|Firmicutes,253HZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02246	1235792.C808_02259	1e-93	278.0	COG4725@1|root,COG4725@2|Bacteria,1TSJV@1239|Firmicutes,248X5@186801|Clostridia,27KVV@186928|unclassified Lachnospiraceae	186801|Clostridia	KT	MT-A70	-	-	-	-	-	-	-	-	-	-	-	-	MT-A70
KFPFDFKC_02247	500632.CLONEX_00708	3.2e-104	305.0	COG4725@1|root,COG4725@2|Bacteria,1TSJV@1239|Firmicutes,248X5@186801|Clostridia	186801|Clostridia	KT	Belongs to the MT-A70-like family	-	-	-	-	-	-	-	-	-	-	-	-	MT-A70
KFPFDFKC_02248	1235798.C817_03187	2.87e-60	188.0	COG3451@1|root,COG3451@2|Bacteria,1TTTW@1239|Firmicutes,25MW3@186801|Clostridia,27WZH@189330|Dorea	186801|Clostridia	U	PrgI family protein	-	-	-	-	-	-	-	-	-	-	-	-	PrgI
KFPFDFKC_02249	1235792.C808_02331	3.71e-20	90.9	COG3843@1|root,COG3843@2|Bacteria,1TR9B@1239|Firmicutes,24A36@186801|Clostridia,27IJ8@186928|unclassified Lachnospiraceae	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
KFPFDFKC_02250	1235802.C823_01674	4.23e-58	184.0	2C2YH@1|root,31RJ6@2|Bacteria,1V7NS@1239|Firmicutes,24M7H@186801|Clostridia,25XC6@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
KFPFDFKC_02251	428125.CLOLEP_03418	2.71e-06	49.7	COG0741@1|root,COG0741@2|Bacteria,1V3F0@1239|Firmicutes,249C4@186801|Clostridia	186801|Clostridia	M	COG COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,Lysozyme_like
KFPFDFKC_02252	1408306.JHXX01000017_gene731	8.39e-44	154.0	COG4806@1|root,COG4806@2|Bacteria,1TS42@1239|Firmicutes,2487G@186801|Clostridia,4BY5U@830|Butyrivibrio	186801|Clostridia	G	L-rhamnose isomerase (RhaA)	rhaA	-	5.3.1.14	ko:K01813	ko00051,ko01120,map00051,map01120	-	R02437	RC00434	ko00000,ko00001,ko01000	-	-	-	RhaA
KFPFDFKC_02253	397288.C806_03269	1.6e-182	509.0	COG0235@1|root,COG0235@2|Bacteria,1TRMG@1239|Firmicutes,24BBT@186801|Clostridia,27IM8@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Class II Aldolase and Adducin N-terminal domain	rhaD	-	4.1.2.19	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01785,R02263	RC00438,RC00599,RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
KFPFDFKC_02254	556261.HMPREF0240_03687	6.7e-83	261.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1TS6T@1239|Firmicutes,247QK@186801|Clostridia,36IQ0@31979|Clostridiaceae	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
KFPFDFKC_02255	1158614.I592_04112	4.84e-196	551.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3,PAE
KFPFDFKC_02256	1158614.I592_04117	0.0	1023.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,4HAAG@91061|Bacilli,4AZJE@81852|Enterococcaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21,3.2.1.52	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	M00628	R00022,R00026,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko00002,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
KFPFDFKC_02257	1158614.I592_04103	6.8e-175	504.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,4HBAI@91061|Bacilli,4B138@81852|Enterococcaceae	91061|Bacilli	G	MFS/sugar transport protein	-	-	-	ko:K16139,ko:K16248	-	-	-	-	ko00000,ko02000	2.A.2	-	-	MFS_2
KFPFDFKC_02258	658655.HMPREF0988_00369	0.0	1171.0	COG3408@1|root,COG3408@2|Bacteria,1TPY5@1239|Firmicutes,249U8@186801|Clostridia,27KIP@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
KFPFDFKC_02259	1158614.I592_04110	1.18e-113	333.0	COG3408@1|root,COG3408@2|Bacteria,1TPY5@1239|Firmicutes,4HDFB@91061|Bacilli	91061|Bacilli	G	Alpha-L-rhamnosidase	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
KFPFDFKC_02260	1232453.BAIF02000098_gene3870	3.11e-222	647.0	COG3408@1|root,COG3408@2|Bacteria,1TPY5@1239|Firmicutes,24ECR@186801|Clostridia	186801|Clostridia	G	Bacterial alpha-L-rhamnosidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
KFPFDFKC_02261	1280686.AUKE01000004_gene247	9.91e-94	283.0	COG2755@1|root,COG2755@2|Bacteria,1V4VT@1239|Firmicutes,25KYG@186801|Clostridia,4C164@830|Butyrivibrio	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
KFPFDFKC_02262	1231336.L248_1080	2.53e-96	305.0	COG2211@1|root,COG2211@2|Bacteria,1VSBF@1239|Firmicutes,4IF5K@91061|Bacilli,3F5PV@33958|Lactobacillaceae	91061|Bacilli	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
KFPFDFKC_02263	1158614.I592_04117	0.0	1438.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,4HAAG@91061|Bacilli,4AZJE@81852|Enterococcaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21,3.2.1.52	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	M00628	R00022,R00026,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko00002,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
KFPFDFKC_02264	658655.HMPREF0988_01010	5.35e-290	815.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,27KJQ@186928|unclassified Lachnospiraceae	186801|Clostridia	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	1.3.1.31	ko:K10797	ko00360,ko01120,map00360,map01120	-	R02252	RC00669	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
KFPFDFKC_02265	1226325.HMPREF1548_00612	7.91e-273	772.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,36EVW@31979|Clostridiaceae	186801|Clostridia	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
KFPFDFKC_02266	1226325.HMPREF1548_00611	0.0	990.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,36F70@31979|Clostridiaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
KFPFDFKC_02267	658655.HMPREF0988_02223	2.48e-182	528.0	COG1874@1|root,COG1874@2|Bacteria,1UZ5Q@1239|Firmicutes,24CFY@186801|Clostridia,27REH@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolases family 35	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_35,Glyco_hydro_42
KFPFDFKC_02268	1235792.C808_02566	2.29e-104	322.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,27J28@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolase family 3 C-terminal domain	bglB	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
KFPFDFKC_02269	1235792.C808_02566	3.29e-28	116.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,27J28@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolase family 3 C-terminal domain	bglB	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
KFPFDFKC_02270	1235792.C808_02345	2.77e-47	154.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31
KFPFDFKC_02272	1410630.JNKP01000005_gene786	2.39e-35	127.0	COG2820@1|root,COG2820@2|Bacteria,1V6T2@1239|Firmicutes,25CZ0@186801|Clostridia,27U7Y@186928|unclassified Lachnospiraceae	186801|Clostridia	F	Phosphorylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
KFPFDFKC_02273	515620.EUBELI_01542	2.84e-192	541.0	COG1502@1|root,COG1502@2|Bacteria,1TRJE@1239|Firmicutes,248ZE@186801|Clostridia,25Z0R@186806|Eubacteriaceae	186801|Clostridia	I	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
KFPFDFKC_02274	883109.HMPREF0380_01476	2.18e-62	192.0	COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,24JGY@186801|Clostridia,3WDDV@538999|Clostridiales incertae sedis	186801|Clostridia	P	ArsC family	spxA	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
KFPFDFKC_02275	411474.COPEUT_00684	2.57e-79	241.0	COG1102@1|root,COG1102@2|Bacteria,1V4ZA@1239|Firmicutes	1239|Firmicutes	F	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
KFPFDFKC_02276	1280694.AUJQ01000020_gene6	2.09e-54	176.0	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,24JAK@186801|Clostridia	186801|Clostridia	C	Bacterial transferase hexapeptide	PaaY	-	-	ko:K02617	-	-	-	-	ko00000	-	-	-	Hexapep,Hexapep_2
KFPFDFKC_02278	622312.ROSEINA2194_03515	7.62e-112	348.0	COG2200@1|root,COG2200@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9
KFPFDFKC_02279	411462.DORLON_02338	1.51e-296	810.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,27UZZ@189330|Dorea	186801|Clostridia	H	Cys/Met metabolism PLP-dependent enzyme	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
KFPFDFKC_02280	585394.RHOM_13220	0.0	1052.0	COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,24978@186801|Clostridia	186801|Clostridia	P	Sulfate transporter	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
KFPFDFKC_02281	97139.C824_03803	3.73e-86	268.0	28M3R@1|root,32UZU@2|Bacteria,1VBVW@1239|Firmicutes,24J58@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02282	1121115.AXVN01000018_gene43	4.37e-150	435.0	COG0503@1|root,COG0503@2|Bacteria,1UZSF@1239|Firmicutes,24FUM@186801|Clostridia,3Y1E0@572511|Blautia	186801|Clostridia	F	Phosphoribosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PRTase_2,TRSP
KFPFDFKC_02283	457412.RSAG_01638	1.58e-201	563.0	COG1358@1|root,COG1358@2|Bacteria,1TP5Y@1239|Firmicutes,2487J@186801|Clostridia,3WH6S@541000|Ruminococcaceae	186801|Clostridia	J	PELOTA RNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PELOTA_1,PRTase_1,PRTase_2,TRSP
KFPFDFKC_02285	457412.RSAG_01637	1.3e-169	480.0	COG2301@1|root,COG2301@2|Bacteria,1TSF2@1239|Firmicutes,249TC@186801|Clostridia,3WJ19@541000|Ruminococcaceae	186801|Clostridia	G	C-C_Bond_Lyase of the TIM-Barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	C-C_Bond_Lyase
KFPFDFKC_02286	397288.C806_01988	9.57e-99	291.0	COG0705@1|root,COG0705@2|Bacteria,1V1C3@1239|Firmicutes,24GPR@186801|Clostridia,27KQ7@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Rhomboid family	-	-	-	ko:K02441	-	-	-	-	ko00000	-	-	-	Rhomboid
KFPFDFKC_02287	1121115.AXVN01000018_gene46	0.0	1170.0	2BVVP@1|root,2Z9CR@2|Bacteria,1TRYC@1239|Firmicutes,2487Q@186801|Clostridia,3Y1D8@572511|Blautia	186801|Clostridia	S	Putative component of 'biosynthetic module'	-	-	-	-	-	-	-	-	-	-	-	-	YceG_bac
KFPFDFKC_02288	1121115.AXVN01000018_gene47	1.07e-207	582.0	COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,3Y1EX@572511|Blautia	186801|Clostridia	P	Toxic anion resistance protein (TelA)	-	-	-	-	-	-	-	-	-	-	-	-	TelA
KFPFDFKC_02289	397291.C804_02843	1.4e-124	356.0	COG2310@1|root,COG2310@2|Bacteria,1TNZQ@1239|Firmicutes,24A3Y@186801|Clostridia,27K57@186928|unclassified Lachnospiraceae	186801|Clostridia	T	TerD domain	terD_2	-	-	ko:K05795	-	-	-	-	ko00000	-	-	-	TerD
KFPFDFKC_02290	1121115.AXVN01000018_gene50	5.68e-113	327.0	COG2310@1|root,COG2310@2|Bacteria,1TR98@1239|Firmicutes,24FZM@186801|Clostridia,3Y13G@572511|Blautia	186801|Clostridia	T	TerD domain	yceC	-	-	-	-	-	-	-	-	-	-	-	TerD
KFPFDFKC_02291	1121115.AXVN01000018_gene51	0.0	1407.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,3XZ0A@572511|Blautia	186801|Clostridia	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
KFPFDFKC_02292	1235799.C818_01135	2.84e-94	285.0	COG0561@1|root,COG0561@2|Bacteria,1V24C@1239|Firmicutes,24HGT@186801|Clostridia,27N1C@186928|unclassified Lachnospiraceae	186801|Clostridia	S	hydrolases of the HAD superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3,S6PP
KFPFDFKC_02293	575593.HMPREF0491_01365	2.22e-130	374.0	COG2013@1|root,COG2013@2|Bacteria,1TSVH@1239|Firmicutes,24DQR@186801|Clostridia,27JVP@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
KFPFDFKC_02294	397291.C804_02849	6.5e-88	268.0	COG2310@1|root,COG2310@2|Bacteria,1V26C@1239|Firmicutes,24GMA@186801|Clostridia,27N1D@186928|unclassified Lachnospiraceae	186801|Clostridia	T	TerD domain	-	-	-	-	-	-	-	-	-	-	-	-	TerD
KFPFDFKC_02295	1410626.JHXB01000003_gene1076	0.000519	45.1	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	ligA1	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF3494
KFPFDFKC_02297	397291.C804_02030	3.74e-284	814.0	COG3250@1|root,COG3250@2|Bacteria,1TS96@1239|Firmicutes,248B9@186801|Clostridia,27JAC@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolases family 2	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
KFPFDFKC_02298	585394.RHOM_10595	4.75e-134	386.0	COG0596@1|root,COG0596@2|Bacteria,1TSU3@1239|Firmicutes,24DYW@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02299	585394.RHOM_10580	6.36e-282	775.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
KFPFDFKC_02300	1280664.AUIX01000001_gene784	1.93e-17	82.8	COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,249IU@186801|Clostridia,4BY4E@830|Butyrivibrio	186801|Clostridia	O	Uncharacterized protein family (UPF0051)	sufB	-	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
KFPFDFKC_02301	1235800.C819_01897	3.88e-133	381.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,27IBR@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
KFPFDFKC_02302	658086.HMPREF0994_04912	7.62e-275	803.0	COG0577@1|root,COG1511@1|root,COG0577@2|Bacteria,COG1511@2|Bacteria,1TPHU@1239|Firmicutes,248RV@186801|Clostridia,27IXQ@186928|unclassified Lachnospiraceae	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
KFPFDFKC_02303	585394.RHOM_04695	4.89e-115	332.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	cmk	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
KFPFDFKC_02304	622312.ROSEINA2194_02909	5.88e-118	348.0	COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,24DE3@186801|Clostridia	186801|Clostridia	P	transport protein CorA	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
KFPFDFKC_02305	1280390.CBQR020000077_gene1694	1.96e-120	352.0	COG1116@1|root,COG1116@2|Bacteria,1TSW5@1239|Firmicutes,4HAFM@91061|Bacilli,26QI3@186822|Paenibacillaceae	91061|Bacilli	P	ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	-	-	-	ko:K15555	ko00920,ko02010,map00920,map02010	M00436	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.17.2	-	-	ABC_tran
KFPFDFKC_02306	663278.Ethha_1750	2.55e-104	312.0	COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,247VM@186801|Clostridia,3WHIC@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport system permease component	ssuC_2	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
KFPFDFKC_02307	1232443.BAIA02000064_gene1097	3.01e-128	377.0	COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,248IG@186801|Clostridia	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
KFPFDFKC_02308	585394.RHOM_13210	5.79e-37	125.0	2E45D@1|root,32Z1F@2|Bacteria,1VEXR@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02309	622312.ROSEINA2194_02907	0.0	1157.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
KFPFDFKC_02310	585394.RHOM_13205	7.6e-72	220.0	2E5KN@1|root,330BS@2|Bacteria,1V5P2@1239|Firmicutes,24IND@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02311	585394.RHOM_13200	0.0	1154.0	28IKE@1|root,2Z8M5@2|Bacteria,1TP2B@1239|Firmicutes,248C2@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	GcvP	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
KFPFDFKC_02312	585394.RHOM_13195	2.9e-47	152.0	COG1925@1|root,COG1925@2|Bacteria,1UFZA@1239|Firmicutes,24MM8@186801|Clostridia	186801|Clostridia	G	Phosphocarrier protein (Hpr)	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
KFPFDFKC_02313	622312.ROSEINA2194_02903	2.05e-32	121.0	2E7V3@1|root,3329Y@2|Bacteria,1VHFN@1239|Firmicutes,24SN8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02314	585394.RHOM_13185	1.73e-270	741.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia	186801|Clostridia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
KFPFDFKC_02315	585394.RHOM_13180	2.76e-174	493.0	COG1484@1|root,COG1484@2|Bacteria,1TPKM@1239|Firmicutes,2483D@186801|Clostridia	186801|Clostridia	L	DNA replication protein	dnaC	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
KFPFDFKC_02316	622312.ROSEINA2194_03797	5.86e-142	414.0	COG3935@1|root,COG3935@2|Bacteria,1TPR5@1239|Firmicutes,248E7@186801|Clostridia	186801|Clostridia	L	DnaD domain protein	dnaD	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
KFPFDFKC_02317	622312.ROSEINA2194_03795	2.7e-285	785.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
KFPFDFKC_02318	585394.RHOM_13160	2.58e-261	721.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,24943@186801|Clostridia	186801|Clostridia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
KFPFDFKC_02319	585394.RHOM_13155	2.53e-246	679.0	COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia	186801|Clostridia	G	glucose-1-phosphate adenylyltransferase GlgD subunit	glgD	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
KFPFDFKC_02320	622312.ROSEINA2194_01451	1.19e-50	160.0	COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,24MVQ@186801|Clostridia	186801|Clostridia	D	Could be involved in septation	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
KFPFDFKC_02321	585394.RHOM_13145	1.18e-144	411.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,248Z3@186801|Clostridia	186801|Clostridia	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
KFPFDFKC_02322	622312.ROSEINA2194_01453	3.06e-113	327.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
KFPFDFKC_02323	585394.RHOM_13135	0.0	1944.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
KFPFDFKC_02324	622312.ROSEINA2194_01455	3.06e-129	381.0	2DCHY@1|root,2ZE7V@2|Bacteria,1UMSB@1239|Firmicutes,25FCG@186801|Clostridia	186801|Clostridia	-	-	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2
KFPFDFKC_02325	622312.ROSEINA2194_01457	1.27e-85	256.0	COG0703@1|root,COG0703@2|Bacteria,1V3W6@1239|Firmicutes,24HKA@186801|Clostridia	186801|Clostridia	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
KFPFDFKC_02326	585394.RHOM_02240	1.39e-209	598.0	COG0739@1|root,COG1388@1|root,COG3583@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,COG3583@2|Bacteria,1TRWJ@1239|Firmicutes,24A2J@186801|Clostridia	186801|Clostridia	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	G5,LysM,Peptidase_M23
KFPFDFKC_02327	622312.ROSEINA2194_01459	1.08e-274	755.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia	186801|Clostridia	M	Belongs to the EPSP synthase family. MurA subfamily	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
KFPFDFKC_02329	1256908.HMPREF0373_02800	5.92e-84	257.0	COG3619@1|root,COG3619@2|Bacteria,1VBGA@1239|Firmicutes,24KG3@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
KFPFDFKC_02330	585394.RHOM_02270	4.53e-154	444.0	COG2206@1|root,COG2206@2|Bacteria,1TR95@1239|Firmicutes,25AZS@186801|Clostridia	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
KFPFDFKC_02331	585394.RHOM_02275	1.18e-273	749.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
KFPFDFKC_02332	585394.RHOM_02280	1.1e-277	769.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,1TPVJ@1239|Firmicutes,2489X@186801|Clostridia	186801|Clostridia	T	Histidine kinase- DNA gyrase B	yycG_1	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
KFPFDFKC_02333	585394.RHOM_02285	5.2e-156	438.0	COG0745@1|root,COG0745@2|Bacteria,1TPRU@1239|Firmicutes,24843@186801|Clostridia	186801|Clostridia	KT	response regulator receiver	srrA_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
KFPFDFKC_02334	585394.RHOM_02290	2.69e-27	101.0	28TG6@1|root,2ZFQ4@2|Bacteria,1W51P@1239|Firmicutes,2575E@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02335	622312.ROSEINA2194_01477	1.04e-110	323.0	COG0564@1|root,COG0564@2|Bacteria,1TX59@1239|Firmicutes,24HTV@186801|Clostridia	186801|Clostridia	J	Pseudouridine synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
KFPFDFKC_02336	585394.RHOM_02305	0.0	908.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
KFPFDFKC_02337	397291.C804_00766	5.08e-231	696.0	COG0457@1|root,COG2199@1|root,COG0457@2|Bacteria,COG2199@2|Bacteria,1VQTU@1239|Firmicutes,24D8M@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
KFPFDFKC_02338	622312.ROSEINA2194_01481	9.02e-245	681.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia	186801|Clostridia	J	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
KFPFDFKC_02339	585394.RHOM_02315	7.31e-144	417.0	COG2334@1|root,COG2334@2|Bacteria,1TTBS@1239|Firmicutes,2483F@186801|Clostridia	186801|Clostridia	S	spore coat protein, CotS	cotS	-	-	ko:K06331,ko:K06337	-	-	-	-	ko00000	-	-	-	APH,Choline_kinase
KFPFDFKC_02340	585394.RHOM_02320	2.38e-136	408.0	28JT6@1|root,2Z9II@2|Bacteria,1V7ZW@1239|Firmicutes,24H3G@186801|Clostridia	186801|Clostridia	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
KFPFDFKC_02341	622312.ROSEINA2194_01484	0.0	1047.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia	186801|Clostridia	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain II	pgcA	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
KFPFDFKC_02342	622312.ROSEINA2194_01485	1.04e-50	161.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
KFPFDFKC_02343	585394.RHOM_02340	2.46e-44	144.0	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,24QNF@186801|Clostridia	186801|Clostridia	J	S4 domain protein	hslR	-	-	-	-	-	-	-	-	-	-	-	S4
KFPFDFKC_02344	622312.ROSEINA2194_01487	1.24e-51	164.0	2E3ZZ@1|root,32YWW@2|Bacteria,1VEIW@1239|Firmicutes,24QNQ@186801|Clostridia	186801|Clostridia	S	Sporulation protein YabP	yabP	-	-	-	-	-	-	-	-	-	-	-	YabP
KFPFDFKC_02345	622312.ROSEINA2194_01488	1.13e-53	173.0	2EFTM@1|root,32YR5@2|Bacteria,1VEV2@1239|Firmicutes	1239|Firmicutes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YabQ
KFPFDFKC_02346	622312.ROSEINA2194_01489	2.92e-34	120.0	COG2919@1|root,COG2919@2|Bacteria,1VGPP@1239|Firmicutes,24R6M@186801|Clostridia	186801|Clostridia	D	septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
KFPFDFKC_02347	622312.ROSEINA2194_01490	1.78e-211	587.0	COG0667@1|root,COG0667@2|Bacteria,1TRS0@1239|Firmicutes,247RJ@186801|Clostridia	186801|Clostridia	C	aldo keto reductase	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
KFPFDFKC_02348	622312.ROSEINA2194_01491	4.75e-310	860.0	COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,247XG@186801|Clostridia	186801|Clostridia	KT	stage ii sporulation protein e	spoIIE	-	3.1.3.16	ko:K06382	-	-	-	-	ko00000,ko01000	-	-	-	SpoIIE
KFPFDFKC_02349	585394.RHOM_02375	6.92e-164	479.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
KFPFDFKC_02350	585394.RHOM_02380	9.54e-101	294.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
KFPFDFKC_02351	585394.RHOM_02385	0.0	1014.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
KFPFDFKC_02352	1280688.AUJB01000008_gene509	1.61e-163	468.0	COG1613@1|root,COG1613@2|Bacteria,1TS25@1239|Firmicutes,24B9S@186801|Clostridia,3NI27@46205|Pseudobutyrivibrio	186801|Clostridia	P	PBP superfamily domain	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
KFPFDFKC_02353	515620.EUBELI_01885	1.18e-156	444.0	COG0555@1|root,COG0555@2|Bacteria,1TQHR@1239|Firmicutes,24ACM@186801|Clostridia,25ZFW@186806|Eubacteriaceae	186801|Clostridia	O	Binding-protein-dependent transport system inner membrane component	cysT	-	-	ko:K02046,ko:K15496	ko00920,ko02010,map00920,map02010	M00185,M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3,3.A.1.6.5	-	-	BPD_transp_1
KFPFDFKC_02354	515620.EUBELI_01884	3.36e-150	427.0	COG4208@1|root,COG4208@2|Bacteria,1TS3N@1239|Firmicutes,24C3X@186801|Clostridia,25VWA@186806|Eubacteriaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
KFPFDFKC_02355	515620.EUBELI_01883	1.49e-168	481.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,25W0F@186806|Eubacteriaceae	186801|Clostridia	E	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	-	3.6.3.25	ko:K02045,ko:K02052	ko00920,ko02010,ko02024,map00920,map02010,map02024	M00185,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_2
KFPFDFKC_02356	1121115.AXVN01000104_gene849	6.48e-280	781.0	COG1053@1|root,COG1053@2|Bacteria,1TRE8@1239|Firmicutes,247TH@186801|Clostridia,3Y0UM@572511|Blautia	186801|Clostridia	C	FAD binding domain	aprA	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
KFPFDFKC_02357	515620.EUBELI_01895	1.86e-50	161.0	COG1146@1|root,COG1146@2|Bacteria,1VADW@1239|Firmicutes,24MQA@186801|Clostridia,25X48@186806|Eubacteriaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_9
KFPFDFKC_02358	1121115.AXVN01000104_gene847	9.04e-198	552.0	COG0175@1|root,COG0175@2|Bacteria,1U1VN@1239|Firmicutes,248Y9@186801|Clostridia,3Y143@572511|Blautia	186801|Clostridia	H	Phosphoadenosine phosphosulfate reductase family	cysD	-	1.8.4.10,1.8.4.8,2.7.7.4	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R02021,R04929	RC00007,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
KFPFDFKC_02359	1449050.JNLE01000003_gene3109	1.16e-279	779.0	COG2895@1|root,COG2895@2|Bacteria,1UI8R@1239|Firmicutes,249BX@186801|Clostridia,36FE5@31979|Clostridiaceae	186801|Clostridia	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
KFPFDFKC_02360	585394.RHOM_02390	2.59e-201	585.0	COG2206@1|root,COG2206@2|Bacteria,1V6IE@1239|Firmicutes,24K4Y@186801|Clostridia	186801|Clostridia	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
KFPFDFKC_02361	622312.ROSEINA2194_01501	0.0	1145.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	tvaI	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,Alpha-amylase_N
KFPFDFKC_02364	585394.RHOM_12785	8.5e-188	546.0	COG0840@1|root,COG3290@1|root,COG0840@2|Bacteria,COG3290@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
KFPFDFKC_02365	585394.RHOM_12780	0.0	1124.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
KFPFDFKC_02366	585394.RHOM_01265	5.07e-165	467.0	2E1XD@1|root,32X6E@2|Bacteria,1VC0W@1239|Firmicutes,24P6H@186801|Clostridia	186801|Clostridia	S	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
KFPFDFKC_02367	585394.RHOM_01325	9.67e-97	283.0	COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,24I4E@186801|Clostridia	186801|Clostridia	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
KFPFDFKC_02368	585394.RHOM_01330	2.35e-87	262.0	COG3247@1|root,COG3247@2|Bacteria,1VBAR@1239|Firmicutes,25CUJ@186801|Clostridia	186801|Clostridia	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
KFPFDFKC_02369	622312.ROSEINA2194_02398	2.55e-231	654.0	COG2199@1|root,COG2206@1|root,COG2199@2|Bacteria,COG2206@2|Bacteria,1V6WM@1239|Firmicutes,24FPG@186801|Clostridia	186801|Clostridia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF,HD,HD_5,HisKA_7TM
KFPFDFKC_02370	622312.ROSEINA2194_02399	4.22e-41	135.0	2E7JQ@1|root,3321V@2|Bacteria,1VH9B@1239|Firmicutes,24S7B@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02371	622312.ROSEINA2194_02400	1.48e-163	468.0	COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,248S5@186801|Clostridia	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
KFPFDFKC_02372	585394.RHOM_01380	3.79e-106	309.0	COG1309@1|root,COG1309@2|Bacteria,1V44I@1239|Firmicutes,24I73@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
KFPFDFKC_02373	1235802.C823_05083	0.0	1009.0	COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,247R6@186801|Clostridia,25UQF@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
KFPFDFKC_02374	585394.RHOM_01390	1.11e-127	412.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia	186801|Clostridia	J	Psort location Cellwall, score	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	-
KFPFDFKC_02375	585394.RHOM_01395	1.36e-87	262.0	COG1971@1|root,COG1971@2|Bacteria,1V9RZ@1239|Firmicutes,24KSZ@186801|Clostridia	186801|Clostridia	P	Probably functions as a manganese efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	Mntp
KFPFDFKC_02376	622312.ROSEINA2194_02404	2.25e-289	810.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia	186801|Clostridia	C	Radical SAM domain protein	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,DUF4080,Radical_SAM
KFPFDFKC_02377	622312.ROSEINA2194_02405	2.66e-93	280.0	COG2176@1|root,COG2176@2|Bacteria,1V3E4@1239|Firmicutes,249X5@186801|Clostridia	186801|Clostridia	L	'dna polymerase iii	-	-	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
KFPFDFKC_02378	585394.RHOM_01415	2.89e-59	191.0	2C456@1|root,32S3D@2|Bacteria,1VBI4@1239|Firmicutes,24N4Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02380	585394.RHOM_01425	1.75e-238	671.0	COG2720@1|root,COG2720@2|Bacteria,1TSH8@1239|Firmicutes,2493X@186801|Clostridia	186801|Clostridia	V	PFAM VanW family protein	-	-	-	ko:K18346	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	G5,PG_binding_4,VanW
KFPFDFKC_02381	585394.RHOM_01430	6.98e-203	565.0	COG0309@1|root,COG0309@2|Bacteria,1TQP4@1239|Firmicutes,24963@186801|Clostridia	186801|Clostridia	O	PFAM AIR synthase related protein	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
KFPFDFKC_02382	622312.ROSEINA2194_02409	7.69e-105	303.0	COG1522@1|root,COG1522@2|Bacteria,1V3PB@1239|Firmicutes,24I3N@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, AsnC family	Lrp	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
KFPFDFKC_02383	585394.RHOM_01440	4.23e-266	730.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia	186801|Clostridia	E	PFAM aminotransferase class I and II	aspC	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
KFPFDFKC_02384	585394.RHOM_01445	2.06e-121	346.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,24HVV@186801|Clostridia	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
KFPFDFKC_02385	585394.RHOM_01450	5.46e-180	504.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA2	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
KFPFDFKC_02386	585394.RHOM_01455	1.04e-191	534.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA2	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
KFPFDFKC_02387	622312.ROSEINA2194_02414	3.49e-163	460.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,248AB@186801|Clostridia	186801|Clostridia	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfT	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
KFPFDFKC_02388	585394.RHOM_01465	3.51e-150	426.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
KFPFDFKC_02389	1415775.U729_2947	1.89e-36	129.0	2E529@1|root,32ZVG@2|Bacteria,1VGFJ@1239|Firmicutes,24R64@186801|Clostridia,36NH8@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
KFPFDFKC_02390	1235798.C817_02114	3.45e-101	311.0	COG0515@1|root,COG0515@2|Bacteria,1V7U3@1239|Firmicutes,25AZB@186801|Clostridia	186801|Clostridia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
KFPFDFKC_02391	1235798.C817_02113	2.02e-17	74.3	2EJDK@1|root,33D4M@2|Bacteria,1VPVH@1239|Firmicutes,24VVZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RHH_5
KFPFDFKC_02392	476272.RUMHYD_01730	1.5e-57	188.0	2DPEI@1|root,331RX@2|Bacteria,1VIYX@1239|Firmicutes,24REE@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF5067)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4352
KFPFDFKC_02393	585394.RHOM_01470	3.97e-97	282.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
KFPFDFKC_02394	585394.RHOM_01475	2.89e-82	244.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
KFPFDFKC_02395	658659.HMPREF0983_01779	6.61e-190	528.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,3VPAB@526524|Erysipelotrichia	526524|Erysipelotrichia	D	CobQ CobB MinD ParA nucleotide binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
KFPFDFKC_02396	658659.HMPREF0983_01778	2.64e-215	595.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,3VQ3M@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
KFPFDFKC_02397	658659.HMPREF0983_01777	1.04e-59	184.0	2B1PF@1|root,31U4Y@2|Bacteria,1V8C1@1239|Firmicutes,3VTMM@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02398	658659.HMPREF0983_01776	1.67e-38	128.0	2E5WX@1|root,330KV@2|Bacteria,1VFRK@1239|Firmicutes,3VU2C@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02399	658659.HMPREF0983_01775	8.64e-178	498.0	COG3935@1|root,COG3935@2|Bacteria,1TPPF@1239|Firmicutes,3VRAV@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_36
KFPFDFKC_02400	658659.HMPREF0983_01774	9.06e-180	500.0	COG3617@1|root,COG3645@1|root,COG3617@2|Bacteria,COG3645@2|Bacteria,1TPKA@1239|Firmicutes,3VQT5@526524|Erysipelotrichia	526524|Erysipelotrichia	K	BRO family, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ANT,Bro-N
KFPFDFKC_02401	658659.HMPREF0983_01773	1.4e-70	212.0	2B1PF@1|root,2ZYHN@2|Bacteria,1V614@1239|Firmicutes,3VRD5@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02402	658659.HMPREF0983_01772	7.77e-98	284.0	28NFE@1|root,2ZBHQ@2|Bacteria,1UFEH@1239|Firmicutes	1239|Firmicutes	S	Domain of unknown function (DUF4313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4313
KFPFDFKC_02403	411471.SUBVAR_04325	2.32e-108	313.0	28I1B@1|root,2Z860@2|Bacteria,1TT6W@1239|Firmicutes,24BUI@186801|Clostridia,3WNZ8@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF3801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3801
KFPFDFKC_02404	658659.HMPREF0983_01770	0.0	1216.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,3VP0A@526524|Erysipelotrichia	526524|Erysipelotrichia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	T4SS-DNA_transf,TraG-D_C
KFPFDFKC_02405	622312.ROSEINA2194_02968	2.04e-58	181.0	COG3655@1|root,COG3655@2|Bacteria,1V27G@1239|Firmicutes,24I0W@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
KFPFDFKC_02406	622312.ROSEINA2194_02967	4.53e-88	258.0	2C5R4@1|root,2ZBQ6@2|Bacteria,1V1T6@1239|Firmicutes,24GMD@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
KFPFDFKC_02407	658655.HMPREF0988_00831	1.32e-121	346.0	COG0617@1|root,COG0617@2|Bacteria,1UZ06@1239|Firmicutes,25D6Y@186801|Clostridia	186801|Clostridia	J	Aminoglycoside-2''-adenylyltransferase	-	-	-	ko:K19545	-	-	-	-	ko00000,ko01504	-	-	-	Aminoglyc_resit
KFPFDFKC_02408	622312.ROSEINA2194_02965	2.86e-187	522.0	COG1396@1|root,COG1396@2|Bacteria,1TT2N@1239|Firmicutes,2488F@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19
KFPFDFKC_02409	500632.CLONEX_04214	1.85e-39	130.0	2CBNR@1|root,32T16@2|Bacteria,1VA97@1239|Firmicutes,24NAW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02410	1235798.C817_01260	1.21e-75	226.0	COG1349@1|root,COG1349@2|Bacteria,1V4EI@1239|Firmicutes,24HRM@186801|Clostridia,27WVB@189330|Dorea	186801|Clostridia	K	DeoR-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_DeoR
KFPFDFKC_02411	411471.SUBVAR_06054	1.17e-57	179.0	2B26K@1|root,31UPX@2|Bacteria,1V93Z@1239|Firmicutes,24JA0@186801|Clostridia,3WJCW@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3847
KFPFDFKC_02412	411459.RUMOBE_00635	7.96e-49	155.0	2CB7P@1|root,32X35@2|Bacteria,1VCII@1239|Firmicutes,24Q2Q@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4318
KFPFDFKC_02413	1235835.C814_02878	0.0	1009.0	COG1196@1|root,COG1196@2|Bacteria,1TPU3@1239|Firmicutes,248HY@186801|Clostridia,3WGDP@541000|Ruminococcaceae	186801|Clostridia	D	MobA MobL family protein	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
KFPFDFKC_02414	457412.RSAG_00538	1.3e-153	431.0	COG0358@1|root,COG0358@2|Bacteria,1TRW1@1239|Firmicutes,249RY@186801|Clostridia,3WH7H@541000|Ruminococcaceae	186801|Clostridia	L	CHC2 zinc finger domain protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHC2
KFPFDFKC_02415	411459.RUMOBE_00632	0.0	906.0	COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,2495S@186801|Clostridia,3XYY4@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	VirE
KFPFDFKC_02416	411459.RUMOBE_00631	4.61e-40	132.0	2CCGJ@1|root,32RVM@2|Bacteria,1VAEN@1239|Firmicutes,24MRI@186801|Clostridia,3Y0DH@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02417	411459.RUMOBE_00630	0.0	1111.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3XYX0@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
KFPFDFKC_02418	428127.EUBDOL_01400	2.81e-199	553.0	28HUM@1|root,2Z81B@2|Bacteria,1TNZ2@1239|Firmicutes,3VQ0C@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02419	658659.HMPREF0983_01767	2.52e-102	296.0	COG3451@1|root,COG3451@2|Bacteria,1V74G@1239|Firmicutes,3VRCI@526524|Erysipelotrichia	526524|Erysipelotrichia	U	PrgI family protein	-	-	-	-	-	-	-	-	-	-	-	-	PrgI
KFPFDFKC_02420	658659.HMPREF0983_01766	0.0	1579.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,3VPNT@526524|Erysipelotrichia	526524|Erysipelotrichia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
KFPFDFKC_02421	411471.SUBVAR_04331	2.59e-83	246.0	2DZH5@1|root,32VAM@2|Bacteria,1V1MR@1239|Firmicutes,24GI9@186801|Clostridia,3WP57@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF3851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3851
KFPFDFKC_02422	658659.HMPREF0983_01764	0.0	1117.0	COG0791@1|root,COG0791@2|Bacteria,1TP24@1239|Firmicutes,3VQ1G@526524|Erysipelotrichia	526524|Erysipelotrichia	M	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP
KFPFDFKC_02423	658659.HMPREF0983_01763	5.25e-45	146.0	2AF03@1|root,314Y6@2|Bacteria,1V9HG@1239|Firmicutes,3VRVP@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Domain of unknown function (DUF4315)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4315
KFPFDFKC_02424	657322.FPR_14220	1.1e-158	447.0	28HUZ@1|root,2Z81G@2|Bacteria,1TS04@1239|Firmicutes,24AUT@186801|Clostridia,3WHA3@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4366)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4366
KFPFDFKC_02425	428127.EUBDOL_00099	1.82e-155	437.0	28IU3@1|root,2Z8SX@2|Bacteria,1UZB0@1239|Firmicutes,3VSYV@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02426	457421.CBFG_04237	0.0	1348.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,268SB@186813|unclassified Clostridiales	186801|Clostridia	L	DNA topoisomerase	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
KFPFDFKC_02427	411470.RUMGNA_00748	1.47e-55	173.0	2AFRJ@1|root,315TI@2|Bacteria,1TUBT@1239|Firmicutes,257XJ@186801|Clostridia,3Y1SN@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02428	428127.EUBDOL_00096	1.69e-96	308.0	COG0358@1|root,COG4227@1|root,COG0358@2|Bacteria,COG4227@2|Bacteria,1TQN4@1239|Firmicutes,3VPGC@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4316,YodL,zf-CHC2
KFPFDFKC_02429	622312.ROSEINA2194_02438	0.0	1726.0	COG0358@1|root,COG4227@1|root,COG0358@2|Bacteria,COG4227@2|Bacteria,1TQN4@1239|Firmicutes,2482H@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4316,Peptidase_M78,YodL,zf-CHC2
KFPFDFKC_02430	428127.EUBDOL_00095	1.85e-44	144.0	2DP0F@1|root,32TXN@2|Bacteria,1UHKP@1239|Firmicutes	1239|Firmicutes	S	Putative tranposon-transfer assisting protein	-	-	-	-	-	-	-	-	-	-	-	-	TTRAP
KFPFDFKC_02431	742733.HMPREF9469_02497	0.0	5521.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,1TPQA@1239|Firmicutes,2491X@186801|Clostridia,21Y2C@1506553|Lachnoclostridium	186801|Clostridia	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,MutS_I,N6_Mtase,SNF2_N
KFPFDFKC_02432	665956.HMPREF1032_01963	3.16e-192	533.0	COG4227@1|root,COG4227@2|Bacteria,1TRWD@1239|Firmicutes,248KN@186801|Clostridia,3WMFR@541000|Ruminococcaceae	186801|Clostridia	L	Protein of unknown function (DUF3848)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3848,DUF3849
KFPFDFKC_02433	585394.RHOM_01940	5.16e-72	216.0	2DFD5@1|root,2ZRE1@2|Bacteria,1V4FG@1239|Firmicutes,25CTT@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	MobC
KFPFDFKC_02434	411461.DORFOR_03176	9.45e-67	202.0	2E6DS@1|root,3311B@2|Bacteria,1VEV3@1239|Firmicutes,25931@186801|Clostridia,27VXS@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02435	585394.RHOM_01950	1.16e-53	169.0	2AJWP@1|root,31AJM@2|Bacteria,1V6IZ@1239|Firmicutes,24NNT@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02436	428127.EUBDOL_01619	4.36e-302	828.0	COG2865@1|root,COG2865@2|Bacteria,1TSPK@1239|Firmicutes,3VRW7@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4
KFPFDFKC_02437	742765.HMPREF9457_02878	0.0	897.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,2481D@186801|Clostridia,27V74@189330|Dorea	186801|Clostridia	U	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
KFPFDFKC_02438	411471.SUBVAR_04358	1.27e-73	221.0	COG1476@1|root,COG1476@2|Bacteria,1V4DH@1239|Firmicutes,24HSN@186801|Clostridia,3WPA3@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
KFPFDFKC_02439	1121115.AXVN01000040_gene3780	2.06e-34	118.0	COG2909@1|root,COG2909@2|Bacteria,1VMYN@1239|Firmicutes	1239|Firmicutes	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02440	411467.BACCAP_03380	1.87e-148	419.0	COG0745@1|root,COG0745@2|Bacteria,1TT12@1239|Firmicutes,24AB1@186801|Clostridia,268QZ@186813|unclassified Clostridiales	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
KFPFDFKC_02441	411467.BACCAP_03381	3.49e-229	639.0	COG0642@1|root,COG2205@2|Bacteria,1TT7F@1239|Firmicutes,247UJ@186801|Clostridia,268Q4@186813|unclassified Clostridiales	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
KFPFDFKC_02442	411467.BACCAP_03382	4.71e-142	403.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,267ZI@186813|unclassified Clostridiales	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
KFPFDFKC_02443	1226325.HMPREF1548_01839	0.0	1079.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,36DMM@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
KFPFDFKC_02444	1256908.HMPREF0373_02163	8.34e-32	113.0	2EPX6@1|root,328RW@2|Bacteria,1UUQ7@1239|Firmicutes,257FE@186801|Clostridia	1256908.HMPREF0373_02163|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02445	658086.HMPREF0994_02833	6.28e-20	85.1	COG1388@1|root,COG1388@2|Bacteria,1VK5T@1239|Firmicutes,24UT1@186801|Clostridia,27Q7D@186928|unclassified Lachnospiraceae	186801|Clostridia	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
KFPFDFKC_02446	585394.RHOM_07575	1.09e-127	365.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia	186801|Clostridia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
KFPFDFKC_02447	585394.RHOM_07570	1.3e-62	193.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,24MVA@186801|Clostridia	186801|Clostridia	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
KFPFDFKC_02448	585394.RHOM_07565	8.96e-103	301.0	COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,24HN2@186801|Clostridia	186801|Clostridia	H	Hydrolase, HD family	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,HD
KFPFDFKC_02449	585394.RHOM_07560	2.54e-87	263.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
KFPFDFKC_02450	585394.RHOM_07555	4.22e-51	162.0	COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,24QZB@186801|Clostridia	186801|Clostridia	J	RNA-binding protein, YhbY family	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
KFPFDFKC_02451	585394.RHOM_07550	2.88e-289	792.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
KFPFDFKC_02452	622312.ROSEINA2194_03722	1.9e-61	188.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
KFPFDFKC_02453	622312.ROSEINA2194_03721	1.19e-62	192.0	COG2868@1|root,COG2868@2|Bacteria	2|Bacteria	J	Cysteine protease Prp	ysxB	-	-	ko:K07584	-	-	-	-	ko00000	-	-	-	Peptidase_Prp
KFPFDFKC_02454	585394.RHOM_07535	6.63e-63	192.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
KFPFDFKC_02455	411463.EUBVEN_00827	4.55e-153	435.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,25VRX@186806|Eubacteriaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
KFPFDFKC_02456	585394.RHOM_07470	2.43e-159	462.0	COG1530@1|root,COG1530@2|Bacteria,1TQS4@1239|Firmicutes,247QV@186801|Clostridia	186801|Clostridia	J	ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1,TRAM
KFPFDFKC_02457	585394.RHOM_07465	9.4e-123	355.0	COG5011@1|root,COG5011@2|Bacteria,1V4D0@1239|Firmicutes,249GU@186801|Clostridia	186801|Clostridia	S	Radical SAM-linked protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
KFPFDFKC_02458	585394.RHOM_07460	0.0	1066.0	COG1032@1|root,COG1032@2|Bacteria,1TR2C@1239|Firmicutes,248HM@186801|Clostridia	186801|Clostridia	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
KFPFDFKC_02460	585394.RHOM_07450	1.67e-124	369.0	COG3274@1|root,COG3274@2|Bacteria,1VSWJ@1239|Firmicutes,248AQ@186801|Clostridia	186801|Clostridia	S	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
KFPFDFKC_02461	397290.C810_00822	7.3e-240	671.0	COG2865@1|root,COG2865@2|Bacteria,1US7F@1239|Firmicutes,24E9U@186801|Clostridia,27MAH@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_24
KFPFDFKC_02462	585394.RHOM_07445	1.45e-268	739.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,247RS@186801|Clostridia	186801|Clostridia	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05760	His_biosynth,PRA-CH,PRA-PH
KFPFDFKC_02463	585394.RHOM_07440	5.47e-123	352.0	COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,247WC@186801|Clostridia	186801|Clostridia	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
KFPFDFKC_02464	622312.ROSEINA2194_03708	1.02e-256	710.0	COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,248X8@186801|Clostridia	186801|Clostridia	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
KFPFDFKC_02465	585394.RHOM_07430	4.38e-142	402.0	COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,249AR@186801|Clostridia	186801|Clostridia	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
KFPFDFKC_02466	622312.ROSEINA2194_03704	1.48e-201	567.0	COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,248CB@186801|Clostridia	186801|Clostridia	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
KFPFDFKC_02467	585394.RHOM_07420	4.26e-109	315.0	COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,24G7S@186801|Clostridia	186801|Clostridia	L	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation	recU	-	-	ko:K03700	-	-	-	-	ko00000,ko03400	-	-	-	RecU
KFPFDFKC_02468	585394.RHOM_07410	2.98e-148	427.0	COG0564@1|root,COG0564@2|Bacteria,1TR1M@1239|Firmicutes,248W3@186801|Clostridia	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
KFPFDFKC_02469	622312.ROSEINA2194_03698	0.0	1144.0	COG1032@1|root,COG1032@2|Bacteria,1TQ8X@1239|Firmicutes,248IW@186801|Clostridia	186801|Clostridia	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
KFPFDFKC_02470	622312.ROSEINA2194_03697	7.47e-119	346.0	COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,248HC@186801|Clostridia	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rsuA	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
KFPFDFKC_02471	585394.RHOM_07395	1.07e-107	320.0	COG0739@1|root,COG0739@2|Bacteria,1TQMQ@1239|Firmicutes,24B3J@186801|Clostridia	186801|Clostridia	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
KFPFDFKC_02472	585394.RHOM_07390	6.22e-263	730.0	COG2195@1|root,COG2195@2|Bacteria,1TQBS@1239|Firmicutes,24860@186801|Clostridia	186801|Clostridia	E	Dipeptidase	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
KFPFDFKC_02473	585394.RHOM_07385	1.35e-102	310.0	COG3314@1|root,COG3314@2|Bacteria,1TR0V@1239|Firmicutes,247XA@186801|Clostridia	186801|Clostridia	S	Sporulation integral membrane protein YlbJ	ylbJ	-	-	-	-	-	-	-	-	-	-	-	Gate
KFPFDFKC_02474	585394.RHOM_07380	7.65e-62	198.0	COG0711@1|root,COG0711@2|Bacteria,1V97P@1239|Firmicutes,24JGQ@186801|Clostridia	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02475	585394.RHOM_07375	8.89e-101	293.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,24HC3@186801|Clostridia	186801|Clostridia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
KFPFDFKC_02476	585394.RHOM_07370	6.22e-96	283.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia	186801|Clostridia	L	RNA methyltransferase, RsmD family	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
KFPFDFKC_02477	585394.RHOM_07365	6.8e-74	226.0	COG1546@1|root,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
KFPFDFKC_02478	585394.RHOM_07360	1.83e-100	294.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
KFPFDFKC_02479	622312.ROSEINA2194_03690	2.37e-289	793.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
KFPFDFKC_02480	622312.ROSEINA2194_03689	1.83e-44	146.0	COG1758@1|root,COG1758@2|Bacteria,1VF65@1239|Firmicutes	1239|Firmicutes	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
KFPFDFKC_02481	622312.ROSEINA2194_03688	7.3e-118	340.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
KFPFDFKC_02482	622312.ROSEINA2194_03687	1.19e-46	150.0	COG2052@1|root,COG2052@2|Bacteria,1VA40@1239|Firmicutes,24MXV@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0296 family	NPD7_560	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
KFPFDFKC_02483	622312.ROSEINA2194_03686	5.82e-166	469.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia	186801|Clostridia	S	TIGR00255 family	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
KFPFDFKC_02484	585394.RHOM_07330	6.72e-96	282.0	COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,24JF2@186801|Clostridia	186801|Clostridia	K	3H domain	niaR	-	-	ko:K07105	-	-	-	-	ko00000	-	-	-	3H,HTH_11
KFPFDFKC_02485	585394.RHOM_07325	2.75e-168	474.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,248P2@186801|Clostridia	186801|Clostridia	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12010	QRPTase_C,QRPTase_N
KFPFDFKC_02486	585394.RHOM_07320	3.49e-256	706.0	COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,25E6F@186801|Clostridia	186801|Clostridia	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
KFPFDFKC_02487	471875.RUMLAC_00642	4.3e-147	422.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,3WGEP@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12020	NadA
KFPFDFKC_02488	622312.ROSEINA2194_03684	1.58e-56	180.0	2BVD7@1|root,32QT8@2|Bacteria,1V6S8@1239|Firmicutes,24HAM@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02489	1042156.CXIVA_21730	7.05e-12	62.8	COG1925@1|root,COG1925@2|Bacteria,1VAQP@1239|Firmicutes,24N19@186801|Clostridia,36M8R@31979|Clostridiaceae	186801|Clostridia	G	phosphocarrier protein HPr	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
KFPFDFKC_02490	585394.RHOM_07305	0.0	929.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,248TP@186801|Clostridia	186801|Clostridia	E	Oligoendopeptidase f	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
KFPFDFKC_02491	585394.RHOM_05265	1.3e-86	313.0	2C4YK@1|root,342PE@2|Bacteria,1VWY9@1239|Firmicutes,24TZZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02492	1410625.JHWK01000004_gene740	1.91e-39	137.0	COG4804@1|root,COG4804@2|Bacteria,1TP7Q@1239|Firmicutes,249TP@186801|Clostridia,27IFF@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF1016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
KFPFDFKC_02493	1235802.C823_04091	4.05e-158	451.0	COG3755@1|root,COG3755@2|Bacteria,1VHSS@1239|Firmicutes,24U0W@186801|Clostridia	186801|Clostridia	S	Lysozyme inhibitor LprI	-	-	-	-	-	-	-	-	-	-	-	-	LprI
KFPFDFKC_02494	713605.ADHG01000006_gene763	7.5e-71	218.0	COG1670@1|root,COG1670@2|Bacteria,1UHY0@1239|Firmicutes,4ISAD@91061|Bacilli,3FBRT@33958|Lactobacillaceae	91061|Bacilli	J	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
KFPFDFKC_02496	622312.ROSEINA2194_01559	0.0	1480.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia	186801|Clostridia	L	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
KFPFDFKC_02497	585394.RHOM_06085	0.0	1505.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,248ZF@186801|Clostridia	186801|Clostridia	L	ATP-dependent helicase nuclease subunit A	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
KFPFDFKC_02498	622312.ROSEINA2194_01555	7.94e-104	305.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
KFPFDFKC_02499	397290.C810_03072	2.71e-37	127.0	2E51P@1|root,32ZV2@2|Bacteria,1VFYG@1239|Firmicutes,24QWN@186801|Clostridia,27P0I@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02500	585394.RHOM_06100	0.0	884.0	COG2509@1|root,COG2509@2|Bacteria,1TP9I@1239|Firmicutes,247QM@186801|Clostridia	186801|Clostridia	S	'oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,HI0933_like,Pyr_redox_2,Thi4
KFPFDFKC_02501	585394.RHOM_06105	4.28e-155	444.0	COG0760@1|root,COG0760@2|Bacteria,1V8DP@1239|Firmicutes,24F9F@186801|Clostridia	186801|Clostridia	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
KFPFDFKC_02502	585394.RHOM_06110	2.38e-254	706.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
KFPFDFKC_02503	585394.RHOM_06120	0.0	921.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia	186801|Clostridia	S	Abc transporter	yfmM	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
KFPFDFKC_02504	1449050.JNLE01000005_gene4440	1.16e-113	345.0	COG0727@1|root,COG0727@2|Bacteria,1UZ5G@1239|Firmicutes,25GD9@186801|Clostridia	186801|Clostridia	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	-
KFPFDFKC_02505	1232453.BAIF02000049_gene828	5e-15	70.1	2ENA7@1|root,33FXX@2|Bacteria,1VMBP@1239|Firmicutes,24USY@186801|Clostridia,26CD2@186813|unclassified Clostridiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02506	1235790.C805_03449	2.66e-59	184.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,24J8R@186801|Clostridia,25WII@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
KFPFDFKC_02507	515620.EUBELI_00188	1.8e-46	153.0	COG1917@1|root,COG1917@2|Bacteria,1TRVH@1239|Firmicutes,249JY@186801|Clostridia,25VK4@186806|Eubacteriaceae	186801|Clostridia	S	conserved protein, contains double-stranded beta-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,CMD,Cupin_2
KFPFDFKC_02508	622312.ROSEINA2194_00296	1.37e-157	447.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,24ADT@186801|Clostridia	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
KFPFDFKC_02511	585394.RHOM_05225	6.79e-189	532.0	COG0630@1|root,COG0630@2|Bacteria,1UHT2@1239|Firmicutes,25EN1@186801|Clostridia	186801|Clostridia	NU	COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
KFPFDFKC_02512	585394.RHOM_05230	3.38e-160	472.0	28I5Y@1|root,2Z892@2|Bacteria,1UYUF@1239|Firmicutes,24CM9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02513	397288.C806_03858	4.48e-19	82.8	2EG0W@1|root,339SX@2|Bacteria,1VKDR@1239|Firmicutes,24TDP@186801|Clostridia,27QMZ@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02517	622312.ROSEINA2194_03514	0.0	2588.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia	186801|Clostridia	I	CoA-substrate-specific enzyme activase	hgdC2	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
KFPFDFKC_02518	585394.RHOM_06185	1.24e-154	440.0	COG0705@1|root,COG0705@2|Bacteria,1TSBP@1239|Firmicutes,249D8@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
KFPFDFKC_02519	622312.ROSEINA2194_04095	5.41e-131	380.0	COG2816@1|root,COG2816@2|Bacteria,1TRMF@1239|Firmicutes,24AXA@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	nudC	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
KFPFDFKC_02521	585394.RHOM_11020	1.24e-173	503.0	COG0845@1|root,COG0845@2|Bacteria,1V4XJ@1239|Firmicutes,25CIU@186801|Clostridia	186801|Clostridia	M	Efflux transporter, RND family, MFP subunit	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
KFPFDFKC_02522	585394.RHOM_11015	9.49e-147	415.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
KFPFDFKC_02523	585394.RHOM_11010	1.1e-243	678.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
KFPFDFKC_02524	585394.RHOM_06145	4.46e-144	412.0	COG0726@1|root,COG0726@2|Bacteria,1TT1X@1239|Firmicutes,249PF@186801|Clostridia	186801|Clostridia	G	delta-lactam-biosynthetic de-N-acetylase	pdaA	-	-	ko:K01567	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
KFPFDFKC_02525	1235799.C818_01516	5.91e-49	194.0	COG3210@1|root,COG3210@2|Bacteria,1UJX3@1239|Firmicutes,25FCY@186801|Clostridia,27IUC@186928|unclassified Lachnospiraceae	186801|Clostridia	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	fn3
KFPFDFKC_02526	622312.ROSEINA2194_02750	1.18e-43	146.0	2FBHF@1|root,343NR@2|Bacteria,1W0XC@1239|Firmicutes,253BM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02527	585394.RHOM_05270	1.21e-226	633.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia	186801|Clostridia	M	Cbs domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
KFPFDFKC_02528	585394.RHOM_05275	0.0	907.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
KFPFDFKC_02529	742738.HMPREF9460_03849	2.35e-153	440.0	COG3943@1|root,COG3943@2|Bacteria,1TPH4@1239|Firmicutes,248NI@186801|Clostridia,268S6@186813|unclassified Clostridiales	186801|Clostridia	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_RhuM
KFPFDFKC_02530	622312.ROSEINA2194_03149	1.99e-107	311.0	COG4636@1|root,COG4636@2|Bacteria,1V4N9@1239|Firmicutes,24CZ1@186801|Clostridia	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
KFPFDFKC_02531	1226322.HMPREF1545_00144	2.57e-42	156.0	COG0582@1|root,COG0582@2|Bacteria,1V16B@1239|Firmicutes,24CY2@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
KFPFDFKC_02533	457412.RSAG_02477	5.39e-271	752.0	COG1055@1|root,COG1055@2|Bacteria,1TT1V@1239|Firmicutes,24ART@186801|Clostridia	186801|Clostridia	P	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
KFPFDFKC_02534	622312.ROSEINA2194_04062	1.66e-157	451.0	COG1102@1|root,COG1102@2|Bacteria,1TSIF@1239|Firmicutes,24BT4@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
KFPFDFKC_02535	585394.RHOM_14385	2.98e-256	711.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
KFPFDFKC_02536	585394.RHOM_14390	2.66e-223	617.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia	186801|Clostridia	C	phosphate acetyltransferase	pta	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
KFPFDFKC_02537	1235790.C805_03317	2.21e-29	112.0	2E5GB@1|root,33080@2|Bacteria,1VF18@1239|Firmicutes,24R5R@186801|Clostridia,25XG3@186806|Eubacteriaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	CorC_HlyC
KFPFDFKC_02538	585394.RHOM_14400	8.16e-97	283.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,24JM2@186801|Clostridia	186801|Clostridia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
KFPFDFKC_02539	585394.RHOM_14405	1.02e-76	235.0	COG1670@1|root,COG1670@2|Bacteria,1V1ZC@1239|Firmicutes,249K2@186801|Clostridia	186801|Clostridia	J	Acetyltransferase GNAT family	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
KFPFDFKC_02540	622312.ROSEINA2194_01957	5.37e-96	294.0	2BZEU@1|root,30VT8@2|Bacteria,1V54M@1239|Firmicutes,24SSI@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02541	585394.RHOM_13060	3.98e-95	306.0	COG2199@1|root,COG2199@2|Bacteria,1V0N3@1239|Firmicutes,24FMU@186801|Clostridia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GGDEF,SBP_bac_3
KFPFDFKC_02542	585394.RHOM_14415	7.6e-76	228.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,24JS4@186801|Clostridia	186801|Clostridia	P	Belongs to the Fur family	perR	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
KFPFDFKC_02543	585394.RHOM_14420	1.44e-122	350.0	COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia	186801|Clostridia	C	Psort location Cytoplasmic, score	rbr3A	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
KFPFDFKC_02544	585394.RHOM_14445	8.5e-67	206.0	2DM5I@1|root,31T37@2|Bacteria,1V6J6@1239|Firmicutes,24K9S@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	SseB
KFPFDFKC_02545	397291.C804_00768	9.21e-188	568.0	COG0642@1|root,COG2205@2|Bacteria,1TP73@1239|Firmicutes,248Y6@186801|Clostridia,27ICQ@186928|unclassified Lachnospiraceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
KFPFDFKC_02546	585394.RHOM_00590	2.5e-141	401.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia	186801|Clostridia	KT	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
KFPFDFKC_02547	585394.RHOM_13945	5.01e-263	728.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
KFPFDFKC_02548	585394.RHOM_00565	0.0	964.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia	186801|Clostridia	L	Belongs to the DEAD box helicase family	cshA	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
KFPFDFKC_02549	585394.RHOM_00560	1.36e-203	584.0	COG0457@1|root,COG2199@1|root,COG0457@2|Bacteria,COG3706@2|Bacteria,1TS77@1239|Firmicutes,24E4N@186801|Clostridia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,sCache_3_3
KFPFDFKC_02550	622312.ROSEINA2194_00437	5.41e-90	274.0	COG0739@1|root,COG0739@2|Bacteria,1VATR@1239|Firmicutes,24N76@186801|Clostridia	186801|Clostridia	M	COG COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
KFPFDFKC_02551	585394.RHOM_00550	8.34e-71	229.0	COG2385@1|root,COG2385@2|Bacteria,1TQSI@1239|Firmicutes,249H0@186801|Clostridia	186801|Clostridia	D	stage II sporulation protein D	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
KFPFDFKC_02553	585394.RHOM_00540	2.94e-186	520.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
KFPFDFKC_02555	642492.Clole_3044	8.78e-143	440.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
KFPFDFKC_02556	622312.ROSEINA2194_00906	1.37e-273	754.0	COG4277@1|root,COG4277@2|Bacteria,1TRT2@1239|Firmicutes,247UD@186801|Clostridia	186801|Clostridia	S	DNA modification repair radical SAM protein	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3,Radical_SAM
KFPFDFKC_02557	622312.ROSEINA2194_00905	1.1e-118	348.0	2DBGV@1|root,2Z969@2|Bacteria,1UI0Y@1239|Firmicutes,25E9X@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4130
KFPFDFKC_02558	622312.ROSEINA2194_00904	1.84e-149	424.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia	186801|Clostridia	L	hydrolase, TatD family	ycfH	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
KFPFDFKC_02561	585394.RHOM_00490	1.11e-39	147.0	2ANQY@1|root,31DQM@2|Bacteria,1V7FM@1239|Firmicutes,24MF6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02562	585394.RHOM_00485	7.38e-124	375.0	2A7KX@1|root,30WIW@2|Bacteria,1V536@1239|Firmicutes,24J38@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02563	585394.RHOM_00480	0.0	1201.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
KFPFDFKC_02565	1121864.OMO_01641	2.34e-85	251.0	2C5R4@1|root,2ZC1N@2|Bacteria,1V292@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
KFPFDFKC_02566	397288.C806_02915	4.37e-50	162.0	COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,24ARG@186801|Clostridia,27J2N@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Appr-1'-p processing enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DUF1768,Macro
KFPFDFKC_02567	515620.EUBELI_20142	1.11e-41	137.0	2DNMA@1|root,32Y3J@2|Bacteria,1VJCJ@1239|Firmicutes,24RI7@186801|Clostridia,25WWU@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02568	411489.CLOL250_01893	1.26e-96	283.0	COG1671@1|root,COG1671@2|Bacteria,1V9Z0@1239|Firmicutes,24HPW@186801|Clostridia,36J4K@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the UPF0178 family	-	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
KFPFDFKC_02569	471875.RUMLAC_02136	2.45e-51	165.0	COG0346@1|root,COG0346@2|Bacteria,1V4DI@1239|Firmicutes,24I5W@186801|Clostridia,3WS7K@541000|Ruminococcaceae	186801|Clostridia	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_2
KFPFDFKC_02570	411489.CLOL250_01520	8.85e-77	229.0	2DMJC@1|root,32RYJ@2|Bacteria,1V4GQ@1239|Firmicutes,24IY2@186801|Clostridia	186801|Clostridia	S	COG NOG13916 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF4186
KFPFDFKC_02571	1235802.C823_01625	4.43e-152	428.0	COG2461@1|root,COG2461@2|Bacteria,1V9ZF@1239|Firmicutes,24F8Y@186801|Clostridia,25XK3@186806|Eubacteriaceae	186801|Clostridia	S	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02572	411489.CLOL250_01311	3.12e-27	109.0	COG2865@1|root,COG2865@2|Bacteria,1TT5X@1239|Firmicutes,24DRB@186801|Clostridia,36RWH@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
KFPFDFKC_02573	1235790.C805_03487	2.35e-110	335.0	COG0542@1|root,COG0542@2|Bacteria,1UZ7G@1239|Firmicutes,24C8B@186801|Clostridia,25YCY@186806|Eubacteriaceae	186801|Clostridia	O	Torsin	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2
KFPFDFKC_02574	1235790.C805_03488	1.13e-99	298.0	2B7B4@1|root,320E7@2|Bacteria,1V8P5@1239|Firmicutes,24NNJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02575	657322.FPR_01850	0.0	1218.0	COG4930@1|root,COG4930@2|Bacteria,1TRIB@1239|Firmicutes,2495B@186801|Clostridia,3WGPP@541000|Ruminococcaceae	186801|Clostridia	O	Putative ATP-dependent Lon protease	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Lon_2,Lon_C
KFPFDFKC_02576	545696.HOLDEFILI_03752	0.0	1077.0	COG1524@1|root,COG1524@2|Bacteria,1TP12@1239|Firmicutes,3VSV1@526524|Erysipelotrichia	526524|Erysipelotrichia	S	PglZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PglZ
KFPFDFKC_02577	1235800.C819_01993	6.42e-100	303.0	2ARUG@1|root,31H61@2|Bacteria,1VA7A@1239|Firmicutes,24ZKC@186801|Clostridia,27QTG@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02578	397290.C810_04453	0.0	1209.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,1TQ39@1239|Firmicutes,24877@186801|Clostridia,27JZV@186928|unclassified Lachnospiraceae	186801|Clostridia	V	restriction	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,N6_Mtase
KFPFDFKC_02579	545696.HOLDEFILI_03754	0.0	1579.0	COG1293@1|root,COG1293@2|Bacteria,1TR5Q@1239|Firmicutes,3VT4I@526524|Erysipelotrichia	526524|Erysipelotrichia	K	RNA-binding protein homologous to eukaryotic snRNP	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02580	1235798.C817_00089	5.73e-88	263.0	28KCG@1|root,2Z9ZE@2|Bacteria,1V34T@1239|Firmicutes,248F6@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF1788)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1788
KFPFDFKC_02581	545696.HOLDEFILI_03756	3.32e-102	300.0	28M7Q@1|root,2ZAM1@2|Bacteria,1UYX7@1239|Firmicutes,3VTHZ@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Putative inner membrane protein (DUF1819)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1819
KFPFDFKC_02582	500635.MITSMUL_03282	1.43e-29	107.0	COG3655@1|root,COG3655@2|Bacteria,1VEM0@1239|Firmicutes,4H5QB@909932|Negativicutes	909932|Negativicutes	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
KFPFDFKC_02583	500632.CLONEX_00595	6.59e-130	379.0	28MNT@1|root,2ZAY9@2|Bacteria,1UJWE@1239|Firmicutes,248QQ@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02584	742765.HMPREF9457_02479	2.58e-156	439.0	COG2088@1|root,COG2088@2|Bacteria,1TVWJ@1239|Firmicutes,25NTX@186801|Clostridia,27X7E@189330|Dorea	186801|Clostridia	D	SpoVG	-	-	-	-	-	-	-	-	-	-	-	-	SpoVG
KFPFDFKC_02585	585394.RHOM_16440	3.89e-72	218.0	2DC0U@1|root,2ZC9U@2|Bacteria,1V2M2@1239|Firmicutes,24GUR@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02586	742765.HMPREF9457_02481	3.25e-129	369.0	COG3764@1|root,COG3764@2|Bacteria,1UN9R@1239|Firmicutes,24CEQ@186801|Clostridia,27WUF@189330|Dorea	186801|Clostridia	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
KFPFDFKC_02587	500632.CLONEX_00591	0.0	2487.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,1TPQA@1239|Firmicutes,2491X@186801|Clostridia	186801|Clostridia	L	helicase C-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,N6_Mtase,ResIII,SNF2_N
KFPFDFKC_02588	500632.CLONEX_00591	0.0	2415.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,1TPQA@1239|Firmicutes,2491X@186801|Clostridia	186801|Clostridia	L	helicase C-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,N6_Mtase,ResIII,SNF2_N
KFPFDFKC_02589	742765.HMPREF9457_02483	3.86e-68	207.0	2A9KM@1|root,30YT6@2|Bacteria,1V3T4@1239|Firmicutes,24IUR@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02590	500632.CLONEX_00589	1.58e-41	136.0	2F899@1|root,32VVS@2|Bacteria,1VDAC@1239|Firmicutes,24NCG@186801|Clostridia	186801|Clostridia	S	DpnD/PcfM-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DpnD-PcfM
KFPFDFKC_02591	742765.HMPREF9457_02485	7.58e-213	588.0	28IAI@1|root,2Z8D4@2|Bacteria,1V027@1239|Firmicutes,24B3S@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02592	742765.HMPREF9457_02486	0.0	956.0	COG0791@1|root,COG0791@2|Bacteria,1UYV9@1239|Firmicutes	1239|Firmicutes	M	NlpC P60 family protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
KFPFDFKC_02593	585394.RHOM_14345	7.9e-247	679.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
KFPFDFKC_02594	622312.ROSEINA2194_00449	2.38e-316	868.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia	186801|Clostridia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
KFPFDFKC_02595	585394.RHOM_14335	1.71e-47	155.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia	186801|Clostridia	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
KFPFDFKC_02596	622312.ROSEINA2194_04436	8.08e-162	455.0	28P0Q@1|root,2ZBX8@2|Bacteria,1V22P@1239|Firmicutes,248XV@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02597	397288.C806_01154	3.64e-90	269.0	COG0582@1|root,COG0582@2|Bacteria,1V2RX@1239|Firmicutes,24DD0@186801|Clostridia,27QUG@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
KFPFDFKC_02598	622312.ROSEINA2194_00548	4.4e-33	117.0	2ENS3@1|root,33GD8@2|Bacteria,1VQH1@1239|Firmicutes,24VFX@186801|Clostridia	186801|Clostridia	S	Global regulator protein family	-	-	-	-	-	-	-	-	-	-	-	-	CsrA
KFPFDFKC_02599	515620.EUBELI_00422	2.91e-129	393.0	COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,25VSN@186806|Eubacteriaceae	186801|Clostridia	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
KFPFDFKC_02600	397287.C807_02862	6.96e-65	219.0	COG0727@1|root,COG0727@2|Bacteria,1TSB6@1239|Firmicutes,24AQ9@186801|Clostridia,27ND9@186928|unclassified Lachnospiraceae	186801|Clostridia	S	N-methylation of lysine residues in flagellin K00599	fliB	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	CxxCxxCC
KFPFDFKC_02601	97138.C820_01583	3.81e-53	184.0	COG5464@1|root,COG5464@2|Bacteria,1UI9X@1239|Firmicutes,25EEV@186801|Clostridia,36UNA@31979|Clostridiaceae	186801|Clostridia	S	Putative transposase, YhgA-like	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02602	1256908.HMPREF0373_01583	3.15e-51	162.0	2DZI1@1|root,32VB8@2|Bacteria,1VAA5@1239|Firmicutes,24MWS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FYDLN_acid
KFPFDFKC_02603	411463.EUBVEN_02075	2.76e-94	278.0	COG0406@1|root,COG0406@2|Bacteria,1V25J@1239|Firmicutes,24FZT@186801|Clostridia,25W5C@186806|Eubacteriaceae	186801|Clostridia	G	Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
KFPFDFKC_02604	622312.ROSEINA2194_00271	1.28e-123	356.0	COG2176@1|root,COG2176@2|Bacteria,1TRS5@1239|Firmicutes,24ER5@186801|Clostridia	186801|Clostridia	L	EXOIII	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	BRCT,RNase_T,zf-C4_Topoisom
KFPFDFKC_02605	140626.JHWB01000022_gene2109	3.94e-31	110.0	2ERQJ@1|root,33J9V@2|Bacteria,1VQ8Z@1239|Firmicutes,24VCG@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02606	585394.RHOM_14945	8.32e-29	103.0	2E7J1@1|root,3321A@2|Bacteria,1VFYW@1239|Firmicutes,24RBB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02607	1280679.ATVX01000017_gene218	2.05e-36	125.0	COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,24QXB@186801|Clostridia,4BZS5@830|Butyrivibrio	186801|Clostridia	C	Acylphosphatase	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
KFPFDFKC_02608	742765.HMPREF9457_00412	5.72e-86	266.0	COG0834@1|root,COG0834@2|Bacteria,1VTCR@1239|Firmicutes,24YIS@186801|Clostridia,27WVQ@189330|Dorea	186801|Clostridia	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
KFPFDFKC_02609	742765.HMPREF9457_00411	7.78e-146	462.0	COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,27WC0@189330|Dorea	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,SBP_bac_3
KFPFDFKC_02610	585394.RHOM_14380	1.04e-173	488.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,24BGW@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
KFPFDFKC_02611	622312.ROSEINA2194_01965	2.94e-251	694.0	COG4284@1|root,COG4284@2|Bacteria,1TQUD@1239|Firmicutes,24A8D@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	2.7.7.23,2.7.7.83	ko:K00972	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00361,M00362	R00416	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
KFPFDFKC_02612	585394.RHOM_14370	1.26e-133	383.0	COG2357@1|root,COG2357@2|Bacteria	2|Bacteria	S	guanosine tetraphosphate metabolic process	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
KFPFDFKC_02613	457421.CBFG_05476	2.62e-59	191.0	2BYWB@1|root,32SGE@2|Bacteria,1VAZ2@1239|Firmicutes,24J86@186801|Clostridia,269B4@186813|unclassified Clostridiales	186801|Clostridia	S	Protein of unknown function (DUF3793)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3793
KFPFDFKC_02614	411469.EUBHAL_03045	4.2e-68	209.0	COG0716@1|root,COG0716@2|Bacteria,1V6D7@1239|Firmicutes,24J7W@186801|Clostridia,25WIN@186806|Eubacteriaceae	186801|Clostridia	C	flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1
KFPFDFKC_02615	936574.HMPREF1508_1331	7.94e-41	135.0	2E4DC@1|root,32Z8R@2|Bacteria,1VF6A@1239|Firmicutes,24QX7@186801|Clostridia	186801|Clostridia	S	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	ko:K19165	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
KFPFDFKC_02616	1410628.JNKS01000004_gene2041	8.11e-73	219.0	COG3654@1|root,COG3654@2|Bacteria,1V6EG@1239|Firmicutes,24J85@186801|Clostridia,27NM5@186928|unclassified Lachnospiraceae	186801|Clostridia	S	TIGRFAM death-on-curing family protein	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
KFPFDFKC_02617	622312.ROSEINA2194_02915	9.32e-224	625.0	COG0534@1|root,COG0534@2|Bacteria,1TP6V@1239|Firmicutes,248EF@186801|Clostridia	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
KFPFDFKC_02618	622312.ROSEINA2194_00445	9.87e-54	171.0	COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,24QRR@186801|Clostridia	186801|Clostridia	S	PFAM Uncharacterised BCR, COG1937	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
KFPFDFKC_02619	622312.ROSEINA2194_00446	0.0	1226.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	actP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
KFPFDFKC_02620	180332.JTGN01000005_gene2749	3.05e-19	79.0	2EIM1@1|root,33CCB@2|Bacteria,1VM79@1239|Firmicutes,24UNI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02621	622312.ROSEINA2194_04435	4.57e-130	371.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
KFPFDFKC_02622	585394.RHOM_14320	4.31e-193	536.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia	186801|Clostridia	G	Transketolase, thiamine diphosphate binding domain	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
KFPFDFKC_02623	622312.ROSEINA2194_04433	5.24e-207	574.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia	186801|Clostridia	G	Transketolase	tktB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
KFPFDFKC_02624	622312.ROSEINA2194_04432	1.24e-106	333.0	COG1652@1|root,COG1652@2|Bacteria,1UIP6@1239|Firmicutes,25EPX@186801|Clostridia	186801|Clostridia	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
KFPFDFKC_02625	585394.RHOM_14305	4.94e-185	526.0	2C3W5@1|root,2ZBIU@2|Bacteria,1UZRE@1239|Firmicutes,24BHB@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02626	622312.ROSEINA2194_04430	3.22e-63	204.0	2DMJ6@1|root,32RY3@2|Bacteria,1VBBI@1239|Firmicutes,24N5I@186801|Clostridia	186801|Clostridia	S	Colicin V production protein	-	-	-	-	-	-	-	-	-	-	-	-	Colicin_V
KFPFDFKC_02627	1280698.AUJS01000099_gene167	1.15e-47	152.0	2CBNB@1|root,32UW5@2|Bacteria,1VCKT@1239|Firmicutes,24N2B@186801|Clostridia,27VS2@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
KFPFDFKC_02628	658659.HMPREF0983_01724	3.54e-297	810.0	COG0582@1|root,COG0582@2|Bacteria,1TSR6@1239|Firmicutes	1239|Firmicutes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
KFPFDFKC_02629	742735.HMPREF9467_04763	2.04e-295	805.0	COG0582@1|root,COG0582@2|Bacteria,1UXHY@1239|Firmicutes,25MEC@186801|Clostridia,221Y0@1506553|Lachnoclostridium	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
KFPFDFKC_02630	585394.RHOM_02025	2.72e-19	84.7	2FJSC@1|root,34BF3@2|Bacteria,1VZYZ@1239|Firmicutes,2549D@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02631	702450.CUW_0318	4.17e-17	80.1	COG1309@1|root,COG1309@2|Bacteria,1V8TI@1239|Firmicutes,3VTTK@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
KFPFDFKC_02632	1117379.BABA_02757	3.35e-16	80.1	COG3315@1|root,COG3315@2|Bacteria,1TSGJ@1239|Firmicutes,4HCZS@91061|Bacilli,1ZDGN@1386|Bacillus	91061|Bacilli	Q	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	LCM
KFPFDFKC_02633	1536774.H70357_11880	3.5e-28	111.0	COG3315@1|root,COG3315@2|Bacteria,1TSGJ@1239|Firmicutes,4HCZS@91061|Bacilli,26V7A@186822|Paenibacillaceae	91061|Bacilli	Q	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	LCM
KFPFDFKC_02634	1226325.HMPREF1548_05583	0.0	1424.0	COG3957@1|root,COG3957@2|Bacteria,1TR23@1239|Firmicutes,24B8I@186801|Clostridia,36G82@31979|Clostridiaceae	186801|Clostridia	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
KFPFDFKC_02635	1235798.C817_05228	4.8e-117	350.0	COG0662@1|root,COG2169@1|root,COG0662@2|Bacteria,COG2169@2|Bacteria,1V9CR@1239|Firmicutes,24K6B@186801|Clostridia,27WPH@189330|Dorea	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
KFPFDFKC_02636	622312.ROSEINA2194_04066	1.29e-69	237.0	COG0840@1|root,COG0840@2|Bacteria,1V0JG@1239|Firmicutes,24A5M@186801|Clostridia	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
KFPFDFKC_02637	1449050.JNLE01000003_gene675	2.84e-75	235.0	COG3279@1|root,COG3279@2|Bacteria,1TSDB@1239|Firmicutes,24MQ4@186801|Clostridia,36KUT@31979|Clostridiaceae	186801|Clostridia	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
KFPFDFKC_02638	622312.ROSEINA2194_01600	3.76e-100	297.0	COG3290@1|root,COG3290@2|Bacteria,1UZ9P@1239|Firmicutes,24MR7@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,SPOB_a
KFPFDFKC_02639	1449050.JNLE01000003_gene677	3.35e-173	513.0	COG1132@1|root,COG1132@2|Bacteria,1TPZP@1239|Firmicutes,249WV@186801|Clostridia,36EX9@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
KFPFDFKC_02640	1449050.JNLE01000003_gene678	1.06e-192	561.0	COG1132@1|root,COG1132@2|Bacteria,1TPZP@1239|Firmicutes,249WV@186801|Clostridia,36EX9@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
KFPFDFKC_02641	180332.JTGN01000011_gene619	5.08e-36	157.0	COG4870@1|root,COG5492@1|root,COG4870@2|Bacteria,COG5492@2|Bacteria,1V2GU@1239|Firmicutes,24GPX@186801|Clostridia	186801|Clostridia	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2,Flg_new,Peptidase_C1
KFPFDFKC_02642	903814.ELI_1175	9.76e-52	204.0	COG3209@1|root,COG3209@2|Bacteria,1UK8Y@1239|Firmicutes,24M4J@186801|Clostridia,25XIP@186806|Eubacteriaceae	186801|Clostridia	M	Listeria-Bacteroides repeat domain (List_Bact_rpt)	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,Flg_new,LRR_5
KFPFDFKC_02643	622312.ROSEINA2194_00234	1.04e-135	395.0	COG0042@1|root,COG0042@2|Bacteria,1TRJM@1239|Firmicutes,247R5@186801|Clostridia	186801|Clostridia	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
KFPFDFKC_02644	1280694.AUJQ01000008_gene158	1.08e-245	689.0	COG3507@1|root,COG3507@2|Bacteria,1TPHA@1239|Firmicutes,24AKT@186801|Clostridia,3NGF5@46205|Pseudobutyrivibrio	186801|Clostridia	G	C-terminal of Glycosyl hydrolases family 43	-	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	Dockerin_1,GH43_C,Glyco_hydro_43,Laminin_G_3
KFPFDFKC_02645	585394.RHOM_08550	1.06e-267	740.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia	186801|Clostridia	E	amino acid carrier protein	agcS	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
KFPFDFKC_02646	1121115.AXVN01000012_gene3113	2.27e-188	528.0	COG3940@1|root,COG3940@2|Bacteria,1TRHI@1239|Firmicutes,24AG6@186801|Clostridia,3Y1H0@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
KFPFDFKC_02647	140626.JHWB01000013_gene760	1.74e-293	809.0	COG3534@1|root,COG3534@2|Bacteria,1TR7B@1239|Firmicutes,248ZA@186801|Clostridia	186801|Clostridia	G	Alpha-L-arabinofuranosidase	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
KFPFDFKC_02648	1280688.AUJB01000008_gene632	5.67e-30	108.0	2DPI5@1|root,3326E@2|Bacteria,1VIQZ@1239|Firmicutes,24UPV@186801|Clostridia,3NIA5@46205|Pseudobutyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02649	1410625.JHWK01000005_gene1207	1.47e-169	479.0	COG4189@1|root,COG4189@2|Bacteria,1TPGD@1239|Firmicutes,248UW@186801|Clostridia,27K27@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
KFPFDFKC_02650	622312.ROSEINA2194_02152	5.71e-61	191.0	COG0622@1|root,COG0622@2|Bacteria,1V7VB@1239|Firmicutes,24PEZ@186801|Clostridia	186801|Clostridia	S	Phosphoesterase	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
KFPFDFKC_02653	97139.C824_00757	1.89e-33	122.0	COG1396@1|root,COG1396@2|Bacteria,1VEU8@1239|Firmicutes,24QN0@186801|Clostridia,36NJZ@31979|Clostridiaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
KFPFDFKC_02660	1410674.JNKU01000023_gene2053	5.36e-39	139.0	2EBJH@1|root,335JZ@2|Bacteria,1VG00@1239|Firmicutes,4HQFE@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02664	658086.HMPREF0994_05194	6.97e-22	97.1	28VH4@1|root,2ZHJM@2|Bacteria,1W2SJ@1239|Firmicutes,25511@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02665	1121946.AUAX01000008_gene7252	0.000247	47.4	COG1396@1|root,COG1396@2|Bacteria,2GXAS@201174|Actinobacteria,4DDF3@85008|Micromonosporales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
KFPFDFKC_02666	411490.ANACAC_02383	1.49e-75	243.0	COG0358@1|root,COG0358@2|Bacteria,1TQTJ@1239|Firmicutes,25C9F@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3991,Toprim_2
KFPFDFKC_02667	1506994.JNLQ01000001_gene362	6.95e-51	174.0	COG1192@1|root,COG1192@2|Bacteria,1V64B@1239|Firmicutes,25CDB@186801|Clostridia,4BWPU@830|Butyrivibrio	186801|Clostridia	D	ATPase MipZ	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
KFPFDFKC_02668	1410624.JNKK01000001_gene603	1.21e-59	201.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia,27J9V@186928|unclassified Lachnospiraceae	186801|Clostridia	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
KFPFDFKC_02670	411902.CLOBOL_05744	2.09e-44	160.0	2F0H7@1|root,340C6@2|Bacteria,1VXA4@1239|Firmicutes,251HD@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02672	1235790.C805_01047	2.59e-61	195.0	COG2003@1|root,COG2003@2|Bacteria,1V38E@1239|Firmicutes,24M00@186801|Clostridia,25WF6@186806|Eubacteriaceae	186801|Clostridia	L	RadC-like JAB domain	-	-	-	-	-	-	-	-	-	-	-	-	RadC
KFPFDFKC_02673	457412.RSAG_01929	4.34e-84	263.0	COG5464@1|root,COG5464@2|Bacteria,1TUFY@1239|Firmicutes,259KT@186801|Clostridia,3WQBQ@541000|Ruminococcaceae	186801|Clostridia	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02674	1442598.JABW01000024_gene1558	2.68e-05	47.8	2AJ3T@1|root,319N6@2|Bacteria,1Q3AM@1224|Proteobacteria,42X0U@68525|delta/epsilon subdivisions,2YQZD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
KFPFDFKC_02676	1410631.JHWZ01000002_gene1291	1.17e-48	182.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,248VT@186801|Clostridia,27T7Y@186928|unclassified Lachnospiraceae	186801|Clostridia	U	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
KFPFDFKC_02678	411463.EUBVEN_00579	2.1e-19	97.8	2CF7U@1|root,2Z7U3@2|Bacteria,1UYHD@1239|Firmicutes,24C76@186801|Clostridia,25UXR@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF3801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3801
KFPFDFKC_02680	397288.C806_04831	7.99e-173	519.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia,27IXT@186928|unclassified Lachnospiraceae	186801|Clostridia	U	Type IV secretory system Conjugative DNA transfer	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf,TraG-D_C
KFPFDFKC_02682	411463.EUBVEN_01667	1.18e-52	180.0	2DB6V@1|root,2Z7IJ@2|Bacteria,1TRNS@1239|Firmicutes,24ANE@186801|Clostridia,25VZH@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02683	411463.EUBVEN_01664	6.47e-06	50.8	28XQJ@1|root,2ZJM8@2|Bacteria,1V2X9@1239|Firmicutes,24E6S@186801|Clostridia,25WT2@186806|Eubacteriaceae	186801|Clostridia	S	PrgI family protein	-	-	-	-	-	-	-	-	-	-	-	-	PrgI
KFPFDFKC_02685	483218.BACPEC_02582	2.01e-260	749.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,248ND@186801|Clostridia,268HK@186813|unclassified Clostridiales	186801|Clostridia	U	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87
KFPFDFKC_02687	411462.DORLON_01893	4.61e-09	64.7	28PM6@1|root,2ZCAA@2|Bacteria,1V4NT@1239|Firmicutes,24HIP@186801|Clostridia,27VG3@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02690	1125701.HMPREF1221_00968	1.89e-224	617.0	COG1533@1|root,COG1533@2|Bacteria,2J5YS@203691|Spirochaetes	203691|Spirochaetes	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
KFPFDFKC_02691	1160721.RBI_I00480	6.39e-166	463.0	COG4422@1|root,COG4422@2|Bacteria,1TPRY@1239|Firmicutes,247VT@186801|Clostridia,3WI0I@541000|Ruminococcaceae	186801|Clostridia	F	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
KFPFDFKC_02692	411474.COPEUT_01929	9.98e-92	269.0	COG1846@1|root,COG1846@2|Bacteria,1V8KT@1239|Firmicutes,24B99@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, MarR family	mgrA	-	-	-	-	-	-	-	-	-	-	-	MarR
KFPFDFKC_02693	457412.RSAG_04508	4.58e-103	298.0	COG0454@1|root,COG0456@2|Bacteria,1V3IC@1239|Firmicutes,24HK5@186801|Clostridia,3WJ6B@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10,Acetyltransf_7
KFPFDFKC_02694	500632.CLONEX_01467	1.71e-65	199.0	COG3070@1|root,COG3070@2|Bacteria,1V42M@1239|Firmicutes,24JNV@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
KFPFDFKC_02695	397288.C806_00900	3.71e-49	156.0	COG3153@1|root,COG3153@2|Bacteria,1VFDX@1239|Firmicutes,24RPM@186801|Clostridia,27PAZ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF3781)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3781
KFPFDFKC_02696	585394.RHOM_14160	0.0	1170.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia	186801|Clostridia	C	NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
KFPFDFKC_02697	585394.RHOM_14155	2.57e-171	479.0	COG1073@1|root,COG1073@2|Bacteria,1UXYN@1239|Firmicutes,24DU6@186801|Clostridia	186801|Clostridia	E	Alpha beta	aroD	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
KFPFDFKC_02698	585394.RHOM_14150	0.0	868.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
KFPFDFKC_02699	585394.RHOM_14145	2.36e-171	481.0	COG2207@1|root,COG2207@2|Bacteria,1V579@1239|Firmicutes,25B25@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
KFPFDFKC_02700	411463.EUBVEN_02138	2.44e-309	845.0	COG0642@1|root,COG2205@2|Bacteria,1TS1G@1239|Firmicutes,248TF@186801|Clostridia,25UVF@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K20487	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
KFPFDFKC_02701	515620.EUBELI_01659	6.14e-155	435.0	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,248WX@186801|Clostridia,25VYC@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
KFPFDFKC_02702	411461.DORFOR_00395	1.39e-173	484.0	COG4200@1|root,COG4200@2|Bacteria,1V4AY@1239|Firmicutes,24EXR@186801|Clostridia,27W6N@189330|Dorea	186801|Clostridia	S	COG NOG31276 non supervised orthologous group	mutG	-	-	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC2_membrane_4
KFPFDFKC_02703	1256908.HMPREF0373_00092	3.25e-166	465.0	COG4200@1|root,COG4200@2|Bacteria,1TRRE@1239|Firmicutes,24AHY@186801|Clostridia,25ZJG@186806|Eubacteriaceae	186801|Clostridia	S	Lantibiotic protection ABC transporter permease subunit, MutE EpiE family	-	-	-	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC2_membrane_4
KFPFDFKC_02704	483218.BACPEC_01813	6.85e-165	461.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,253U3@186801|Clostridia,268VZ@186813|unclassified Clostridiales	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00254,M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC_tran
KFPFDFKC_02705	1280698.AUJS01000042_gene3279	1.26e-115	333.0	COG2265@1|root,COG2265@2|Bacteria,1UK4G@1239|Firmicutes,24H6A@186801|Clostridia,27W5R@189330|Dorea	186801|Clostridia	J	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
KFPFDFKC_02706	483218.BACPEC_00659	9.74e-41	147.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,267VV@186813|unclassified Clostridiales	186801|Clostridia	L	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
KFPFDFKC_02707	411463.EUBVEN_02568	0.0	1145.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,25UYJ@186806|Eubacteriaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
KFPFDFKC_02708	515620.EUBELI_20651	6.37e-232	639.0	COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,24B0E@186801|Clostridia,25UVN@186806|Eubacteriaceae	186801|Clostridia	M	Choloylglycine hydrolase	cbh	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
KFPFDFKC_02709	483218.BACPEC_02237	3.54e-31	111.0	2F14R@1|root,33U60@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02710	622312.ROSEINA2194_02846	2.55e-130	370.0	COG0558@1|root,COG0558@2|Bacteria,1V4YR@1239|Firmicutes,24FWZ@186801|Clostridia	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
KFPFDFKC_02711	411469.EUBHAL_01648	1.36e-250	688.0	2C2TA@1|root,2Z7T7@2|Bacteria,1TS53@1239|Firmicutes,248BA@186801|Clostridia,25W0J@186806|Eubacteriaceae	186801|Clostridia	S	CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
KFPFDFKC_02712	471875.RUMLAC_00940	6.44e-241	663.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,249HQ@186801|Clostridia,3WHVM@541000|Ruminococcaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
KFPFDFKC_02713	511680.BUTYVIB_02272	5.44e-155	435.0	COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,248B6@186801|Clostridia,4C156@830|Butyrivibrio	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
KFPFDFKC_02714	585394.RHOM_13740	0.0	961.0	COG1502@1|root,COG1502@2|Bacteria,1TSN8@1239|Firmicutes,249G7@186801|Clostridia	186801|Clostridia	I	COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
KFPFDFKC_02715	411463.EUBVEN_02552	4.83e-93	272.0	28N68@1|root,2ZBB7@2|Bacteria,1UZ5P@1239|Firmicutes,24EZI@186801|Clostridia,25Y5Y@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02716	411463.EUBVEN_02551	0.0	877.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,25VD8@186806|Eubacteriaceae	186801|Clostridia	C	citrate synthase	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
KFPFDFKC_02717	585394.RHOM_13755	0.0	1054.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
KFPFDFKC_02718	500632.CLONEX_00605	4.68e-90	265.0	COG0073@1|root,COG0073@2|Bacteria,1V496@1239|Firmicutes,24J1W@186801|Clostridia	186801|Clostridia	J	Putative tRNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_bind
KFPFDFKC_02719	515620.EUBELI_20140	1.11e-111	322.0	COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,24ARG@186801|Clostridia,25UV0@186806|Eubacteriaceae	186801|Clostridia	S	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	-	-	-	-	-	-	-	-	-	Macro
KFPFDFKC_02720	515620.EUBELI_20142	6.43e-41	135.0	2DNMA@1|root,32Y3J@2|Bacteria,1VJCJ@1239|Firmicutes,24RI7@186801|Clostridia,25WWU@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02721	511680.BUTYVIB_01643	1.74e-96	282.0	COG1671@1|root,COG1671@2|Bacteria,1V9Z0@1239|Firmicutes,24HPW@186801|Clostridia	186801|Clostridia	O	Belongs to the UPF0178 family	-	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
KFPFDFKC_02722	471875.RUMLAC_02136	1.48e-52	168.0	COG0346@1|root,COG0346@2|Bacteria,1V4DI@1239|Firmicutes,24I5W@186801|Clostridia,3WS7K@541000|Ruminococcaceae	186801|Clostridia	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_2
KFPFDFKC_02723	411489.CLOL250_01520	1.02e-76	229.0	2DMJC@1|root,32RYJ@2|Bacteria,1V4GQ@1239|Firmicutes,24IY2@186801|Clostridia	186801|Clostridia	S	COG NOG13916 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF4186
KFPFDFKC_02724	515620.EUBELI_20144	1.36e-20	86.7	COG5015@1|root,COG5015@2|Bacteria,1V43Y@1239|Firmicutes,24HQB@186801|Clostridia,25WPW@186806|Eubacteriaceae	186801|Clostridia	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
KFPFDFKC_02725	622312.ROSEINA2194_02849	2.2e-255	736.0	COG2206@1|root,COG2206@2|Bacteria,1V6WM@1239|Firmicutes,24FPG@186801|Clostridia	186801|Clostridia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF,HD,HD_5,HisKA_7TM
KFPFDFKC_02726	1469948.JPNB01000001_gene792	1.34e-66	212.0	COG5523@1|root,COG5523@2|Bacteria,1V6FC@1239|Firmicutes,24JPX@186801|Clostridia,36WXQ@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
KFPFDFKC_02727	585394.RHOM_05735	5.41e-304	844.0	COG1404@1|root,COG1404@2|Bacteria,1TQK9@1239|Firmicutes,25B1U@186801|Clostridia	186801|Clostridia	O	Belongs to the peptidase S8 family	cspBA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
KFPFDFKC_02728	1469948.JPNB01000003_gene64	2.24e-93	281.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,247R1@186801|Clostridia,36H17@31979|Clostridiaceae	186801|Clostridia	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
KFPFDFKC_02729	622312.ROSEINA2194_03967	5.33e-61	189.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
KFPFDFKC_02730	622312.ROSEINA2194_03968	9.74e-145	410.0	COG3279@1|root,COG3279@2|Bacteria	2|Bacteria	KT	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
KFPFDFKC_02731	622312.ROSEINA2194_03969	2.03e-245	681.0	COG3290@1|root,COG3290@2|Bacteria,1V46S@1239|Firmicutes,24KBY@186801|Clostridia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
KFPFDFKC_02733	622312.ROSEINA2194_03971	3.59e-90	268.0	COG4512@1|root,COG4512@2|Bacteria	2|Bacteria	KOT	PFAM Accessory gene regulator B	-	-	-	ko:K07813	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	AgrB
KFPFDFKC_02734	622312.ROSEINA2194_03103	3.56e-282	781.0	COG2304@1|root,COG2304@2|Bacteria,1VDD4@1239|Firmicutes,24B6V@186801|Clostridia	186801|Clostridia	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
KFPFDFKC_02735	622312.ROSEINA2194_03105	0.0	1384.0	2C1IS@1|root,2Z86T@2|Bacteria,1TQRA@1239|Firmicutes,247QX@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02736	622312.ROSEINA2194_03106	3.62e-89	262.0	2AGPY@1|root,309PS@2|Bacteria,1V64Q@1239|Firmicutes,24FXN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02737	622312.ROSEINA2194_03107	2.04e-85	253.0	2AGPY@1|root,316XK@2|Bacteria,1V241@1239|Firmicutes,24GUS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02738	622312.ROSEINA2194_03108	1.42e-73	223.0	COG0484@1|root,COG0484@2|Bacteria,1VAWE@1239|Firmicutes	1239|Firmicutes	O	Molecular chaperone	dnaJ3	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ
KFPFDFKC_02739	622312.ROSEINA2194_03109	6.59e-118	338.0	COG1716@1|root,COG1716@2|Bacteria,1VFJ4@1239|Firmicutes,24Q0H@186801|Clostridia	186801|Clostridia	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
KFPFDFKC_02740	622312.ROSEINA2194_03110	2.86e-123	350.0	COG1716@1|root,COG1716@2|Bacteria,1UZ57@1239|Firmicutes,24PC6@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
KFPFDFKC_02741	622312.ROSEINA2194_03111	6.02e-183	510.0	COG0631@1|root,COG0631@2|Bacteria,1V094@1239|Firmicutes,24N9G@186801|Clostridia	186801|Clostridia	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2,SpoIIE
KFPFDFKC_02742	622312.ROSEINA2194_03112	0.0	888.0	COG0631@1|root,COG0631@2|Bacteria,1TQWN@1239|Firmicutes,247KV@186801|Clostridia	186801|Clostridia	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
KFPFDFKC_02743	622312.ROSEINA2194_03113	1.17e-276	759.0	28ISJ@1|root,2Z8RQ@2|Bacteria,1TRGC@1239|Firmicutes,24CC6@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02744	622312.ROSEINA2194_03114	1.02e-142	405.0	28N97@1|root,2ZBD9@2|Bacteria,1UYY7@1239|Firmicutes,24MD6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02745	622312.ROSEINA2194_03115	0.0	1695.0	COG0443@1|root,COG0443@2|Bacteria,1TT0Z@1239|Firmicutes,24AG5@186801|Clostridia	186801|Clostridia	O	Heat shock 70 kDa protein	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02746	622312.ROSEINA2194_03938	4.05e-125	360.0	28N3U@1|root,2ZB9G@2|Bacteria,1V09T@1239|Firmicutes,2493C@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02747	622312.ROSEINA2194_03937	2.67e-111	320.0	2EFPB@1|root,32SG8@2|Bacteria,1UPYZ@1239|Firmicutes,25HS3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02748	622312.ROSEINA2194_03936	0.0	884.0	COG3501@1|root,COG3501@2|Bacteria,1V043@1239|Firmicutes,248CZ@186801|Clostridia	186801|Clostridia	S	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
KFPFDFKC_02749	622312.ROSEINA2194_03935	1.32e-144	409.0	2EFPB@1|root,339FB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02750	622312.ROSEINA2194_03934	2.75e-74	227.0	2ER0I@1|root,33IK3@2|Bacteria,1UJZR@1239|Firmicutes,24V5I@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02751	622312.ROSEINA2194_03933	3.01e-120	343.0	2E4BD@1|root,32Z71@2|Bacteria,1VFIN@1239|Firmicutes,24NQT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02752	1410632.JHWW01000013_gene228	3.01e-05	52.4	COG5492@1|root,COG5492@2|Bacteria,1V62C@1239|Firmicutes	1239|Firmicutes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Flg_new
KFPFDFKC_02753	585394.RHOM_05265	5.84e-87	312.0	2C4YK@1|root,342PE@2|Bacteria,1VWY9@1239|Firmicutes,24TZZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02754	1408323.JQKK01000037_gene3044	4.31e-212	593.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,27KDJ@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Probable transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
KFPFDFKC_02755	622312.ROSEINA2194_01722	2.27e-206	571.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
KFPFDFKC_02756	457412.RSAG_01929	1.16e-79	251.0	COG5464@1|root,COG5464@2|Bacteria,1TUFY@1239|Firmicutes,259KT@186801|Clostridia,3WQBQ@541000|Ruminococcaceae	186801|Clostridia	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02758	1408324.JNJK01000031_gene3548	1.07e-102	324.0	COG0507@1|root,COG0507@2|Bacteria	2|Bacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
KFPFDFKC_02761	886882.PPSC2_p0035	3.91e-79	261.0	COG0358@1|root,COG0358@2|Bacteria,1UYVG@1239|Firmicutes	1239|Firmicutes	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3854,zf-CHC2
KFPFDFKC_02763	585394.RHOM_16640	1.99e-70	215.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia	186801|Clostridia	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
KFPFDFKC_02764	742733.HMPREF9469_00876	7.55e-75	244.0	COG3831@1|root,COG3831@2|Bacteria	2|Bacteria	-	-	-	-	2.4.2.30	ko:K10798	ko03410,ko04210,ko04212,ko04214,ko04217,map03410,map04210,map04212,map04214,map04217	M00296	-	-	ko00000,ko00001,ko00002,ko01000,ko03032,ko03036,ko03400	-	-	-	DUF4240,PARP,PARP_reg,WGR
KFPFDFKC_02775	511680.BUTYVIB_01441	7.16e-105	318.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,25C3N@186801|Clostridia,4BY3G@830|Butyrivibrio	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
KFPFDFKC_02785	397290.C810_03260	4.01e-50	171.0	2F0A9@1|root,33TDH@2|Bacteria,1VRZZ@1239|Firmicutes,24YBB@186801|Clostridia,27S9K@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02786	33035.JPJF01000016_gene4083	6.82e-64	202.0	2DIV4@1|root,30473@2|Bacteria,1V5EC@1239|Firmicutes,24IZE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02787	411463.EUBVEN_02693	2.29e-139	397.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6Q@186801|Clostridia,25VMP@186806|Eubacteriaceae	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
KFPFDFKC_02788	585394.RHOM_14685	8.34e-38	127.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01165	ATP-synt_C
KFPFDFKC_02789	411463.EUBVEN_02695	5.02e-62	196.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,24RWR@186801|Clostridia,25X82@186806|Eubacteriaceae	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
KFPFDFKC_02790	622312.ROSEINA2194_02212	4.68e-62	196.0	COG0712@1|root,COG0712@2|Bacteria,1UI0C@1239|Firmicutes,24G5C@186801|Clostridia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
KFPFDFKC_02791	622312.ROSEINA2194_02211	0.0	875.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP
KFPFDFKC_02792	585394.RHOM_14665	6.19e-175	492.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
KFPFDFKC_02793	585394.RHOM_14660	0.0	871.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
KFPFDFKC_02794	585394.RHOM_14655	7.38e-78	233.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
KFPFDFKC_02795	658086.HMPREF0994_01674	1.76e-68	222.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1V41T@1239|Firmicutes,25B4Q@186801|Clostridia,27TZT@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
KFPFDFKC_02796	397291.C804_03759	0.0	1057.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,27IMH@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
KFPFDFKC_02797	622312.ROSEINA2194_00571	0.0	1217.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolase family 3 N-terminal domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
KFPFDFKC_02798	411474.COPEUT_01236	3.11e-299	894.0	COG4124@1|root,COG4733@1|root,COG4124@2|Bacteria,COG4733@2|Bacteria,1TSXQ@1239|Firmicutes,24CRT@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 26 family	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	CBM27,CBM_11,CW_binding_1,Glyco_hydro_26,Gram_pos_anchor,SLH
KFPFDFKC_02799	641107.CDLVIII_5765	9.59e-100	297.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,36E89@31979|Clostridiaceae	186801|Clostridia	E	ABC transporter	-	-	-	ko:K10010	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.10,3.A.1.3.14	-	-	ABC_tran
KFPFDFKC_02800	641107.CDLVIII_5764	9.19e-81	248.0	COG0765@1|root,COG0765@2|Bacteria,1TPQ8@1239|Firmicutes,24BX1@186801|Clostridia,36FAP@31979|Clostridiaceae	186801|Clostridia	E	acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine	-	-	-	ko:K10009	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.10,3.A.1.3.14	-	-	BPD_transp_1
KFPFDFKC_02801	794846.AJQU01000046_gene4554	1.12e-77	243.0	COG0834@1|root,COG0834@2|Bacteria,1MXME@1224|Proteobacteria,2TT4J@28211|Alphaproteobacteria,4BBEK@82115|Rhizobiaceae	28211|Alphaproteobacteria	ET	belongs to the bacterial solute-binding protein 3 family	tcyA	-	-	ko:K02424	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3.10,3.A.1.3.14	-	-	SBP_bac_3
KFPFDFKC_02802	1410633.JHWR01000001_gene1255	8.15e-128	398.0	COG2200@1|root,COG2200@2|Bacteria,1V15N@1239|Firmicutes,24C2G@186801|Clostridia,27K15@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL
KFPFDFKC_02803	585394.RHOM_06170	0.0	1018.0	COG3867@1|root,COG3867@2|Bacteria,1TQDZ@1239|Firmicutes,24CPM@186801|Clostridia	186801|Clostridia	G	arabinogalactan	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,Glyco_hydro_53
KFPFDFKC_02804	585394.RHOM_08575	1.09e-190	564.0	COG0840@1|root,COG0840@2|Bacteria,1UYFA@1239|Firmicutes,24F3M@186801|Clostridia	186801|Clostridia	NT	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal,PilZ
KFPFDFKC_02805	658086.HMPREF0994_03302	9.48e-54	172.0	COG2315@1|root,COG2315@2|Bacteria	2|Bacteria	V	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
KFPFDFKC_02808	515620.EUBELI_20437	9.82e-135	421.0	COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia,25ZJN@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
KFPFDFKC_02809	1304866.K413DRAFT_4331	3.96e-113	366.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,36DH1@31979|Clostridiaceae	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
KFPFDFKC_02810	397291.C804_02931	1.45e-105	318.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,27UBJ@186928|unclassified Lachnospiraceae	186801|Clostridia	GK	ROK family	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI,ROK
KFPFDFKC_02811	397288.C806_01642	3.57e-115	346.0	COG1609@1|root,COG1609@2|Bacteria,1TT82@1239|Firmicutes,24G8D@186801|Clostridia,27QNK@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR,Peripla_BP_1
KFPFDFKC_02812	397288.C806_01638	4.32e-192	546.0	COG3538@1|root,COG3538@2|Bacteria,1TRJI@1239|Firmicutes,248YF@186801|Clostridia,27JVW@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Pfam:DUF1237	-	-	-	ko:K09704	-	-	-	-	ko00000	-	-	-	Glyco_hydro_125
KFPFDFKC_02813	702450.CUW_2164	0.0	1165.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,3VPJS@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
KFPFDFKC_02814	397291.C804_02930	0.0	1294.0	COG3291@1|root,COG4724@1|root,COG3291@2|Bacteria,COG4724@2|Bacteria,1TPGB@1239|Firmicutes,24AII@186801|Clostridia	186801|Clostridia	G	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_85,PKD
KFPFDFKC_02815	1280673.AUJJ01000001_gene2237	3.66e-139	405.0	COG1609@1|root,COG1609@2|Bacteria,1TRG8@1239|Firmicutes,249CT@186801|Clostridia,4BZ5Y@830|Butyrivibrio	186801|Clostridia	K	Periplasmic binding protein-like domain	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
KFPFDFKC_02816	1280676.AUJO01000002_gene1480	6.37e-194	541.0	COG4209@1|root,COG4209@2|Bacteria,1TQFY@1239|Firmicutes,24923@186801|Clostridia,4BX4G@830|Butyrivibrio	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
KFPFDFKC_02817	1280676.AUJO01000002_gene1479	1.79e-175	494.0	COG0395@1|root,COG0395@2|Bacteria,1TP1G@1239|Firmicutes,247T2@186801|Clostridia,4C1Y7@830|Butyrivibrio	186801|Clostridia	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K17320	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
KFPFDFKC_02818	1280676.AUJO01000002_gene1478	5.44e-257	716.0	COG1653@1|root,COG1653@2|Bacteria,1TPWV@1239|Firmicutes,24AWQ@186801|Clostridia,4BYV9@830|Butyrivibrio	186801|Clostridia	G	Domain of unknown function (DUF3502)	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	DUF3502,SBP_bac_1,SBP_bac_8
KFPFDFKC_02819	397291.C804_02928	2.22e-217	602.0	COG2152@1|root,COG2152@2|Bacteria,1TQE7@1239|Firmicutes,249D0@186801|Clostridia,27JZU@186928|unclassified Lachnospiraceae	186801|Clostridia	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	2.4.1.319,2.4.1.320	ko:K18785	-	-	R10811,R10829	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
KFPFDFKC_02820	457412.RSAG_02071	0.0	932.0	COG1874@1|root,COG1874@2|Bacteria,1UZRC@1239|Firmicutes,24EDS@186801|Clostridia	186801|Clostridia	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02821	658086.HMPREF0994_01029	7.66e-244	703.0	28I74@1|root,2Z8A0@2|Bacteria,1VR23@1239|Firmicutes	1239|Firmicutes	S	COG NOG26804 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02822	397291.C804_02929	0.0	1610.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,248VH@186801|Clostridia,27KWU@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
KFPFDFKC_02823	1128421.JAGA01000003_gene2954	9.5e-31	130.0	COG2211@1|root,COG2211@2|Bacteria,2NR8E@2323|unclassified Bacteria	2|Bacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
KFPFDFKC_02824	1195236.CTER_1937	4.71e-263	753.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia	186801|Clostridia	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
KFPFDFKC_02825	658086.HMPREF0994_03950	1.59e-209	605.0	COG3525@1|root,COG3525@2|Bacteria,1TSXM@1239|Firmicutes,248U1@186801|Clostridia,27QES@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolase family 20, domain 2	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_20,Glyco_hydro_20b
KFPFDFKC_02826	622312.ROSEINA2194_03990	8.08e-105	305.0	COG2002@1|root,COG2002@2|Bacteria,1V02A@1239|Firmicutes,248XR@186801|Clostridia	186801|Clostridia	K	stage V sporulation protein T	spoVT	-	-	ko:K04769	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin,SpoVT_C
KFPFDFKC_02827	622312.ROSEINA2194_03989	2.87e-168	479.0	COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,24BN3@186801|Clostridia	186801|Clostridia	L	Ser Thr phosphatase family protein	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
KFPFDFKC_02828	622312.ROSEINA2194_03988	4.42e-137	416.0	COG4717@1|root,COG4717@2|Bacteria,1TQP3@1239|Firmicutes,24E0A@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23,AAA_27
KFPFDFKC_02829	622312.ROSEINA2194_03986	0.0	978.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,248A4@186801|Clostridia	186801|Clostridia	M	penicillin-binding protein 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
KFPFDFKC_02830	622312.ROSEINA2194_03984	1.07e-194	543.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia	186801|Clostridia	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
KFPFDFKC_02831	585394.RHOM_14100	1.07e-123	357.0	COG3859@1|root,COG3859@2|Bacteria,1V1WX@1239|Firmicutes,24E4Z@186801|Clostridia	186801|Clostridia	S	Proton-coupled thiamine transporter YuaJ	yuaJ	-	-	ko:K16789	-	-	-	-	ko00000,ko02000	2.A.88.3	-	-	Thia_YuaJ
KFPFDFKC_02832	397291.C804_05932	1e-129	382.0	COG0614@1|root,COG0614@2|Bacteria,1UIJ9@1239|Firmicutes,25BH2@186801|Clostridia	186801|Clostridia	P	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
KFPFDFKC_02833	397291.C804_04092	1.26e-163	476.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia,27TN6@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15755	HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase
KFPFDFKC_02834	585394.RHOM_14885	7.39e-37	130.0	COG1669@1|root,COG1669@2|Bacteria,1VBYU@1239|Firmicutes,24N0Y@186801|Clostridia	186801|Clostridia	S	TIGRFAM nucleotidyltransferase substrate binding protein, HI0074 family	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2,NTase_sub_bind
KFPFDFKC_02835	1469948.JPNB01000001_gene1957	6.41e-57	181.0	COG0386@1|root,COG0386@2|Bacteria,1V3M3@1239|Firmicutes,24HGF@186801|Clostridia,36IXW@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the glutathione peroxidase family	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
KFPFDFKC_02836	397291.C804_05931	1.38e-113	334.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,27MTD@186928|unclassified Lachnospiraceae	186801|Clostridia	HP	ATPases associated with a variety of cellular activities	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
KFPFDFKC_02837	397291.C804_05930	1.74e-142	412.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,24BGM@186801|Clostridia,27U55@186928|unclassified Lachnospiraceae	186801|Clostridia	P	FecCD transport family	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
KFPFDFKC_02838	1262449.CP6013_1068	1.05e-34	121.0	COG1733@1|root,COG1733@2|Bacteria,1V707@1239|Firmicutes,24HCZ@186801|Clostridia,36IYB@31979|Clostridiaceae	186801|Clostridia	K	PFAM helix-turn-helix HxlR type	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
KFPFDFKC_02839	585394.RHOM_04795	5.27e-61	195.0	COG1342@1|root,COG1433@1|root,COG1342@2|Bacteria,COG1433@2|Bacteria,1TRMQ@1239|Firmicutes,25E8C@186801|Clostridia	186801|Clostridia	O	dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	DUF134,Nitro_FeMo-Co
KFPFDFKC_02840	1235802.C823_04050	2.91e-103	302.0	COG3506@1|root,COG3506@2|Bacteria,1TSXY@1239|Firmicutes,2484H@186801|Clostridia,25Y9J@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1349)	-	-	-	ko:K09702	-	-	-	-	ko00000	-	-	-	DUF1349
KFPFDFKC_02841	622312.ROSEINA2194_00219	1.78e-248	686.0	COG0738@1|root,COG0738@2|Bacteria,1TQPE@1239|Firmicutes,24AF8@186801|Clostridia	186801|Clostridia	G	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
KFPFDFKC_02842	622312.ROSEINA2194_00218	1.17e-168	476.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1V0PV@1239|Firmicutes,24BUX@186801|Clostridia	186801|Clostridia	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
KFPFDFKC_02843	483218.BACPEC_01206	3.8e-231	644.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,2683I@186813|unclassified Clostridiales	186801|Clostridia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
KFPFDFKC_02844	483218.BACPEC_01205	3.26e-169	477.0	COG2221@1|root,COG2221@2|Bacteria,1TR7P@1239|Firmicutes,2493K@186801|Clostridia,269QP@186813|unclassified Clostridiales	186801|Clostridia	C	Nitrite/Sulfite reductase ferredoxin-like half domain	-	-	-	ko:K00385	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	Fer4,Fer4_7,NIR_SIR,NIR_SIR_ferr
KFPFDFKC_02845	483218.BACPEC_01204	2.7e-45	147.0	COG0425@1|root,COG0425@2|Bacteria,1VBET@1239|Firmicutes,24NV0@186801|Clostridia	186801|Clostridia	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
KFPFDFKC_02846	483218.BACPEC_01203	1.81e-42	141.0	COG0526@1|root,COG0526@2|Bacteria,1UHN6@1239|Firmicutes,25FT1@186801|Clostridia	186801|Clostridia	O	Thioredoxin	trxA1	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
KFPFDFKC_02847	483218.BACPEC_01202	2.65e-29	105.0	COG2104@1|root,COG2104@2|Bacteria,1VFJR@1239|Firmicutes,24SEU@186801|Clostridia	186801|Clostridia	H	thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
KFPFDFKC_02848	483218.BACPEC_01201	4.81e-183	510.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,25CJC@186801|Clostridia,269P8@186813|unclassified Clostridiales	186801|Clostridia	H	ThiF family	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
KFPFDFKC_02849	1160721.RBI_I01804	2.66e-56	179.0	COG1310@1|root,COG1310@2|Bacteria,1V6TY@1239|Firmicutes,24JI8@186801|Clostridia,3WJ1M@541000|Ruminococcaceae	186801|Clostridia	S	Mov34 MPN PAD-1 family	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
KFPFDFKC_02850	180332.JTGN01000013_gene974	8.34e-33	146.0	COG2340@1|root,COG3087@1|root,COG3507@1|root,COG3533@1|root,COG2340@2|Bacteria,COG3087@2|Bacteria,COG3507@2|Bacteria,COG3533@2|Bacteria,1TRV9@1239|Firmicutes,24CKP@186801|Clostridia	186801|Clostridia	G	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127
KFPFDFKC_02851	1449050.JNLE01000003_gene2095	8.69e-16	91.7	COG0304@1|root,COG2273@1|root,COG2340@1|root,COG3291@1|root,COG0304@2|Bacteria,COG2273@2|Bacteria,COG2340@2|Bacteria,COG3291@2|Bacteria,1TR5U@1239|Firmicutes,248GW@186801|Clostridia,36HJG@31979|Clostridiaceae	186801|Clostridia	G	family 16	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,DUF1533,Glyco_hydro_16,SLH
KFPFDFKC_02852	622312.ROSEINA2194_00812	4.47e-35	120.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
KFPFDFKC_02853	622312.ROSEINA2194_00811	1.63e-180	507.0	COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,24831@186801|Clostridia	186801|Clostridia	S	reductase II	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iHN637.CLJU_RS20775	NMO
KFPFDFKC_02854	622312.ROSEINA2194_00810	1.02e-150	432.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia	186801|Clostridia	I	malonyl coa-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
KFPFDFKC_02855	476272.RUMHYD_01858	2.15e-115	337.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,3XYM7@572511|Blautia	186801|Clostridia	IQ	Psort location Cytoplasmic, score	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
KFPFDFKC_02856	585394.RHOM_14065	8.69e-242	671.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
KFPFDFKC_02857	622312.ROSEINA2194_00807	4.38e-80	239.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,24JAW@186801|Clostridia	186801|Clostridia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
KFPFDFKC_02858	585394.RHOM_14055	0.0	942.0	COG0777@1|root,COG0825@1|root,COG0777@2|Bacteria,COG0825@2|Bacteria,1TP4U@1239|Firmicutes,248QK@186801|Clostridia	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20740	ACCA,Carboxyl_trans
KFPFDFKC_02859	622312.ROSEINA2194_00805	1.28e-166	473.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
KFPFDFKC_02861	585394.RHOM_14045	9.97e-77	231.0	COG1846@1|root,COG1846@2|Bacteria,1V6GY@1239|Firmicutes,24HTB@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
KFPFDFKC_02862	622312.ROSEINA2194_02852	1.35e-176	498.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia	186801|Clostridia	C	Belongs to the LDH MDH superfamily. LDH family	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
KFPFDFKC_02863	518637.EUBIFOR_00314	7.19e-31	108.0	2BEFR@1|root,33CRA@2|Bacteria,1VQ4D@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02864	1256908.HMPREF0373_03376	9.56e-75	225.0	COG5658@1|root,COG5658@2|Bacteria,1VB6E@1239|Firmicutes,24MSY@186801|Clostridia,25XHU@186806|Eubacteriaceae	186801|Clostridia	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	SdpI
KFPFDFKC_02865	585394.RHOM_02660	1.78e-33	126.0	COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,247MA@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
KFPFDFKC_02866	585394.RHOM_02665	8.93e-164	462.0	COG3833@1|root,COG3833@2|Bacteria,1TRB7@1239|Firmicutes,24DNI@186801|Clostridia	186801|Clostridia	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
KFPFDFKC_02867	585394.RHOM_14040	3.88e-42	139.0	2C5I7@1|root,330HE@2|Bacteria,1VJU8@1239|Firmicutes,24SCX@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.75	-	-	-	-	-	-	-	-	-	-	-	-	DUF4321
KFPFDFKC_02868	1235790.C805_03587	2.17e-117	356.0	COG2340@1|root,COG2340@2|Bacteria,1V1IM@1239|Firmicutes,24GB5@186801|Clostridia,25WC7@186806|Eubacteriaceae	186801|Clostridia	N	hydrolase, family 25	-	-	-	-	-	-	-	-	-	-	-	-	CAP,SLH
KFPFDFKC_02869	622312.ROSEINA2194_00803	0.0	869.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia	186801|Clostridia	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
KFPFDFKC_02870	585394.RHOM_14030	1.71e-43	150.0	COG0582@1|root,COG0582@2|Bacteria,1TSN5@1239|Firmicutes,248E3@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
KFPFDFKC_02871	585394.RHOM_14010	1.72e-142	407.0	28JTW@1|root,2Z9J1@2|Bacteria	2|Bacteria	S	Phage replisome organizer, N-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_rep_org_N
KFPFDFKC_02872	585394.RHOM_14005	4.7e-109	316.0	2E210@1|root,32X8X@2|Bacteria,1VC8E@1239|Firmicutes,24PXS@186801|Clostridia	186801|Clostridia	S	Loader and inhibitor of phage G40P	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_G39P
KFPFDFKC_02873	397290.C810_04584	9.71e-47	153.0	296J0@1|root,2ZR9N@2|Bacteria,1VAUS@1239|Firmicutes,24PMT@186801|Clostridia,27UEK@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
KFPFDFKC_02874	718252.FP2_12450	3.71e-159	450.0	COG1396@1|root,COG1396@2|Bacteria,1VF0W@1239|Firmicutes,24R43@186801|Clostridia,3WJ1R@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
KFPFDFKC_02875	585394.RHOM_13985	5.14e-38	130.0	COG0745@1|root,COG0745@2|Bacteria,1VCPH@1239|Firmicutes,24MRK@186801|Clostridia	186801|Clostridia	KT	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
KFPFDFKC_02876	585394.RHOM_13955	9.09e-50	158.0	COG2161@1|root,COG2161@2|Bacteria,1VA5D@1239|Firmicutes,24NDD@186801|Clostridia	186801|Clostridia	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
KFPFDFKC_02877	585394.RHOM_13950	5.55e-56	175.0	COG3668@1|root,COG3668@2|Bacteria,1VGR8@1239|Firmicutes,24KGA@186801|Clostridia	186801|Clostridia	S	addiction module toxin, RelE StbE family	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
KFPFDFKC_02878	762984.HMPREF9445_00895	1.05e-119	380.0	COG3972@1|root,COG3972@2|Bacteria,4NWIE@976|Bacteroidetes	976|Bacteroidetes	F	UvrD-like helicase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	UvrD_C_2
KFPFDFKC_02881	585394.RHOM_13940	1.34e-85	253.0	COG0517@1|root,COG0517@2|Bacteria,1V7XE@1239|Firmicutes,24HF5@186801|Clostridia	186801|Clostridia	S	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
KFPFDFKC_02882	622312.ROSEINA2194_01023	5.4e-175	503.0	COG0534@1|root,COG0534@2|Bacteria,1TPPJ@1239|Firmicutes,25AZE@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
KFPFDFKC_02883	622312.ROSEINA2194_01022	3.22e-78	247.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,1V48S@1239|Firmicutes,24F7N@186801|Clostridia	186801|Clostridia	KT	transcriptional regulator	bltR	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
KFPFDFKC_02884	411461.DORFOR_00949	2.24e-28	111.0	2CJI5@1|root,32SA3@2|Bacteria,1VAH5@1239|Firmicutes,24MTX@186801|Clostridia,27VSK@189330|Dorea	186801|Clostridia	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
KFPFDFKC_02886	622312.ROSEINA2194_00787	2.25e-303	838.0	COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,24978@186801|Clostridia	186801|Clostridia	P	Sulfate transporter	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
KFPFDFKC_02887	1235793.C809_01839	2.26e-54	171.0	COG3695@1|root,COG3695@2|Bacteria,1UIU9@1239|Firmicutes,25ES2@186801|Clostridia,27UK4@186928|unclassified Lachnospiraceae	186801|Clostridia	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
KFPFDFKC_02888	622312.ROSEINA2194_00788	6.32e-83	247.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
KFPFDFKC_02889	471875.RUMLAC_00843	4.72e-63	199.0	28PZ1@1|root,2ZCII@2|Bacteria,1V2GX@1239|Firmicutes,24IE1@186801|Clostridia,3WK3Z@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function, E. rectale Gene description (DUF3877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3877
KFPFDFKC_02890	585394.RHOM_13905	0.0	1195.0	COG0119@1|root,COG2207@1|root,COG0119@2|Bacteria,COG2207@2|Bacteria,1TP4Y@1239|Firmicutes,2485A@186801|Clostridia	186801|Clostridia	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,HTH_18,LeuA_dimer
KFPFDFKC_02891	1226325.HMPREF1548_05938	2.85e-65	200.0	COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,24MSE@186801|Clostridia,36KQ7@31979|Clostridiaceae	186801|Clostridia	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
KFPFDFKC_02893	180332.JTGN01000006_gene3154	5.14e-173	496.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia	186801|Clostridia	M	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
KFPFDFKC_02895	622312.ROSEINA2194_03131	1.61e-244	676.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
KFPFDFKC_02896	622312.ROSEINA2194_03130	2e-92	271.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia	186801|Clostridia	C	assembly protein, NifU family	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
KFPFDFKC_02897	1298920.KI911353_gene3328	2.19e-265	732.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,21XFB@1506553|Lachnoclostridium	186801|Clostridia	E	Psort location Cytoplasmic, score 9.98	MET17	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
KFPFDFKC_02898	1341157.RF007C_10565	1.36e-173	489.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,3WG9Z@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
KFPFDFKC_02899	585394.RHOM_13855	3.19e-95	282.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB_1	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
KFPFDFKC_02900	585394.RHOM_13850	1.88e-205	577.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
KFPFDFKC_02901	877424.ATWC01000015_gene633	9.78e-133	389.0	COG3437@1|root,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,27IRU@186928|unclassified Lachnospiraceae	186801|Clostridia	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
KFPFDFKC_02902	877424.ATWC01000015_gene634	6.12e-202	607.0	COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia,27ISK@186928|unclassified Lachnospiraceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,GAF_2,HATPase_c,HisKA,Hpt,Response_reg
KFPFDFKC_02903	877424.ATWC01000015_gene635	1.34e-266	772.0	COG0642@1|root,COG0784@1|root,COG1307@1|root,COG0784@2|Bacteria,COG1307@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,27I9U@186928|unclassified Lachnospiraceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	DegV,HATPase_c,HisKA,Hpt,Response_reg
KFPFDFKC_02904	1321778.HMPREF1982_03315	1.37e-159	458.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,26A16@186813|unclassified Clostridiales	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
KFPFDFKC_02905	1341157.RF007C_08915	1.53e-88	266.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,24FVK@186801|Clostridia,3WIGR@541000|Ruminococcaceae	186801|Clostridia	H	riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
KFPFDFKC_02906	1321778.HMPREF1982_03317	1.36e-241	669.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,26AE5@186813|unclassified Clostridiales	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
KFPFDFKC_02907	1410633.JHWR01000016_gene1040	1.13e-84	252.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,24FRS@186801|Clostridia,27M62@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
KFPFDFKC_02908	1235800.C819_01131	1.54e-20	93.2	28J9U@1|root,2Z94P@2|Bacteria,1UYN9@1239|Firmicutes,248AD@186801|Clostridia,27PA2@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02909	511680.BUTYVIB_01764	1.3e-131	374.0	2CZHY@1|root,32T6E@2|Bacteria,1VDM1@1239|Firmicutes,24MKX@186801|Clostridia	186801|Clostridia	S	Putative zincin peptidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3267
KFPFDFKC_02910	742765.HMPREF9457_03575	1.93e-139	394.0	COG2267@1|root,COG2267@2|Bacteria,1TT75@1239|Firmicutes,25FMP@186801|Clostridia	186801|Clostridia	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
KFPFDFKC_02911	622312.ROSEINA2194_03257	3.15e-31	109.0	298S6@1|root,2ZVWG@2|Bacteria,1W22G@1239|Firmicutes,256U8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02912	585394.RHOM_13845	0.0	1164.0	COG1368@1|root,COG1368@2|Bacteria,1TQYQ@1239|Firmicutes,25CNS@186801|Clostridia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
KFPFDFKC_02913	1235793.C809_00618	3.31e-69	213.0	COG0315@1|root,COG0315@2|Bacteria,1V3J4@1239|Firmicutes,24H9F@186801|Clostridia,27MYG@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
KFPFDFKC_02914	1298920.KI911353_gene811	2.4e-77	234.0	COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,21Z3U@1506553|Lachnoclostridium	186801|Clostridia	H	Molybdenum cofactor synthesis domain protein	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
KFPFDFKC_02915	1256908.HMPREF0373_01402	7.37e-99	293.0	COG0425@1|root,COG0425@2|Bacteria,1V6BY@1239|Firmicutes,24JW8@186801|Clostridia,25X3M@186806|Eubacteriaceae	186801|Clostridia	O	DsrE/DsrF-like family	yedF	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE,TusA
KFPFDFKC_02916	1298920.KI911353_gene785	3.04e-174	497.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,21Z7G@1506553|Lachnoclostridium	186801|Clostridia	E	Cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
KFPFDFKC_02917	1235792.C808_01660	2.49e-193	542.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,27JZ4@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
KFPFDFKC_02918	1256908.HMPREF0373_00762	3.84e-29	105.0	29XBV@1|root,30J1M@2|Bacteria,1U4VY@1239|Firmicutes,25NV8@186801|Clostridia,25Z8B@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
KFPFDFKC_02919	657322.FPR_30730	6.17e-126	366.0	COG3608@1|root,COG3608@2|Bacteria,1TRKT@1239|Firmicutes,2492W@186801|Clostridia,3WI66@541000|Ruminococcaceae	186801|Clostridia	S	Selenium-dependent molybdenum hydroxylase system protein, YqeB family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3
KFPFDFKC_02920	411469.EUBHAL_01351	1.35e-195	548.0	COG0303@1|root,COG0303@2|Bacteria,1TP7F@1239|Firmicutes,247TZ@186801|Clostridia,25VS2@186806|Eubacteriaceae	186801|Clostridia	H	Probable molybdopterin binding domain	moeA2	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
KFPFDFKC_02921	658088.HMPREF0987_01753	5.82e-108	325.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,27IWC@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
KFPFDFKC_02922	1256908.HMPREF0373_01761	2.27e-81	243.0	COG2258@1|root,COG2258@2|Bacteria,1V6DS@1239|Firmicutes,24HBA@186801|Clostridia,25X6H@186806|Eubacteriaceae	186801|Clostridia	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
KFPFDFKC_02923	626939.HMPREF9443_01887	1.7e-86	269.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,4H521@909932|Negativicutes	909932|Negativicutes	O	XdhC and CoxI family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
KFPFDFKC_02924	1042156.CXIVA_05850	4.81e-125	367.0	COG0725@1|root,COG0725@2|Bacteria,1U9U3@1239|Firmicutes,249VA@186801|Clostridia,36EBM@31979|Clostridiaceae	186801|Clostridia	P	ABC transporter, periplasmic molybdate-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	iHN637.CLJU_RS12820	SBP_bac_11
KFPFDFKC_02925	411468.CLOSCI_02058	5.26e-131	375.0	COG4149@1|root,COG4149@2|Bacteria,1TRNA@1239|Firmicutes,24BR9@186801|Clostridia,21XZN@1506553|Lachnoclostridium	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
KFPFDFKC_02926	1042156.CXIVA_05830	1.83e-124	369.0	COG1118@1|root,COG1118@2|Bacteria,1UI1E@1239|Firmicutes,25EAE@186801|Clostridia,36EU6@31979|Clostridiaceae	186801|Clostridia	P	the current gene model (or a revised gene model) may contain a frame shift	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
KFPFDFKC_02927	931626.Awo_c29210	1.33e-67	220.0	COG0583@1|root,COG0583@2|Bacteria,1TP6T@1239|Firmicutes,24970@186801|Clostridia,25WDP@186806|Eubacteriaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
KFPFDFKC_02928	585394.RHOM_13830	1.45e-133	381.0	COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,24AEE@186801|Clostridia	186801|Clostridia	E	L-serine dehydratase, iron-sulfur-dependent, beta subunit	sdaAB	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	ACT,SDH_beta
KFPFDFKC_02929	585394.RHOM_13825	4.8e-165	466.0	COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,2480J@186801|Clostridia	186801|Clostridia	E	L-serine dehydratase, iron-sulfur-dependent, alpha subunit	sdaAA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha
KFPFDFKC_02931	622312.ROSEINA2194_02263	1.93e-67	206.0	COG1725@1|root,COG1725@2|Bacteria,1VAC6@1239|Firmicutes,24MVE@186801|Clostridia	186801|Clostridia	K	PFAM Bacterial regulatory proteins, gntR family	-	-	-	-	-	-	-	-	-	-	-	-	GntR
KFPFDFKC_02932	622312.ROSEINA2194_02264	2.88e-174	489.0	COG1131@1|root,COG1131@2|Bacteria,1TS5Y@1239|Firmicutes,24AH1@186801|Clostridia	186801|Clostridia	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
KFPFDFKC_02934	622312.ROSEINA2194_02266	1.62e-60	197.0	2DRS1@1|root,33CTC@2|Bacteria,1VPFR@1239|Firmicutes,24X55@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02935	585394.RHOM_13820	5.69e-315	858.0	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia	186801|Clostridia	C	PFAM Acetyl-CoA hydrolase transferase	cat	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
KFPFDFKC_02938	665956.HMPREF1032_01818	1.47e-27	105.0	COG1695@1|root,COG1695@2|Bacteria,1VHJD@1239|Firmicutes,24QBN@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, PadR family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
KFPFDFKC_02941	585394.RHOM_13815	8.98e-209	582.0	COG0463@1|root,COG0463@2|Bacteria,1TQEM@1239|Firmicutes,249HH@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,TPR_8
KFPFDFKC_02942	585394.RHOM_13805	6.32e-274	751.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,247TI@186801|Clostridia	186801|Clostridia	J	SMART PUA domain containing protein	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PUA
KFPFDFKC_02943	1235793.C809_01456	4.37e-83	249.0	COG0778@1|root,COG0778@2|Bacteria,1V3YJ@1239|Firmicutes,24BKH@186801|Clostridia,27KJP@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
KFPFDFKC_02944	397288.C806_00845	1.88e-54	172.0	COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,24JJB@186801|Clostridia,27NDR@186928|unclassified Lachnospiraceae	186801|Clostridia	K	HxlR-like helix-turn-helix	hxlR	-	-	-	-	-	-	-	-	-	-	-	HxlR
KFPFDFKC_02945	585394.RHOM_13395	3.43e-260	732.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
KFPFDFKC_02946	483218.BACPEC_00278	7.23e-51	160.0	2CZEX@1|root,32T68@2|Bacteria,1VB18@1239|Firmicutes,24MZP@186801|Clostridia,269KN@186813|unclassified Clostridiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02947	483218.BACPEC_00279	0.0	1663.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,268JZ@186813|unclassified Clostridiales	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
KFPFDFKC_02948	483218.BACPEC_00280	2.9e-150	423.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,2689T@186813|unclassified Clostridiales	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
KFPFDFKC_02949	483218.BACPEC_00281	1.78e-191	534.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia,268Z5@186813|unclassified Clostridiales	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
KFPFDFKC_02950	1121115.AXVN01000010_gene2772	3.02e-153	431.0	COG0745@1|root,COG0745@2|Bacteria,1TSNV@1239|Firmicutes,2493A@186801|Clostridia,3Y04C@572511|Blautia	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
KFPFDFKC_02951	411473.RUMCAL_02060	2.61e-280	766.0	COG1191@1|root,COG1191@2|Bacteria,1U0Q7@1239|Firmicutes,249NN@186801|Clostridia,3WNXR@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02952	518637.EUBIFOR_00315	1.18e-79	243.0	COG1073@1|root,COG1073@2|Bacteria,1UK94@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
KFPFDFKC_02953	483218.BACPEC_00285	2.31e-258	709.0	28ICW@1|root,2Z8F5@2|Bacteria,1TSMN@1239|Firmicutes,24BRU@186801|Clostridia,269YH@186813|unclassified Clostridiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02954	411473.RUMCAL_02064	1.18e-142	403.0	COG0358@1|root,COG0358@2|Bacteria,1V0WR@1239|Firmicutes,24C9Q@186801|Clostridia,3WI6F@541000|Ruminococcaceae	186801|Clostridia	L	CHC2 zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHC2
KFPFDFKC_02955	411473.RUMCAL_02065	0.0	919.0	COG3378@1|root,COG3378@2|Bacteria,1TSGZ@1239|Firmicutes,24CI8@186801|Clostridia,3WHNR@541000|Ruminococcaceae	186801|Clostridia	S	Phage plasmid primase, P4 family	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	D5_N,Pox_D5
KFPFDFKC_02956	411473.RUMCAL_02067	2.52e-284	780.0	COG1196@1|root,COG1196@2|Bacteria,1UQCD@1239|Firmicutes,24AY9@186801|Clostridia,3WSPG@541000|Ruminococcaceae	186801|Clostridia	D	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
KFPFDFKC_02957	483218.BACPEC_00290	1.2e-29	105.0	2DXUK@1|root,346PC@2|Bacteria,1VZRU@1239|Firmicutes,25418@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02958	483218.BACPEC_00291	7.34e-47	150.0	COG2944@1|root,COG2944@2|Bacteria,1VIYC@1239|Firmicutes,24RHE@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
KFPFDFKC_02959	483218.BACPEC_00292	0.0	1042.0	COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,25B03@186801|Clostridia,26CHB@186813|unclassified Clostridiales	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
KFPFDFKC_02960	622312.ROSEINA2194_02320	1.16e-161	456.0	2C8US@1|root,33EYV@2|Bacteria,1VRE4@1239|Firmicutes,24XSX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02963	397291.C804_05689	1.86e-90	270.0	2E7UB@1|root,3329C@2|Bacteria,1VHFQ@1239|Firmicutes,24SM4@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02964	622312.ROSEINA2194_02322	0.0	1065.0	2DBKH@1|root,2Z9T5@2|Bacteria,1TQWZ@1239|Firmicutes,24D49@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
KFPFDFKC_02966	622312.ROSEINA2194_02324	1.74e-168	471.0	2DGTD@1|root,2ZX87@2|Bacteria,1V45H@1239|Firmicutes,24GH9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02967	397291.C804_05693	3.24e-210	584.0	COG0338@1|root,COG0338@2|Bacteria,1UBIY@1239|Firmicutes,248RN@186801|Clostridia,27TJ8@186928|unclassified Lachnospiraceae	186801|Clostridia	L	D12 class N6 adenine-specific DNA methyltransferase	dam	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
KFPFDFKC_02968	622312.ROSEINA2194_02327	1.41e-98	286.0	COG2002@1|root,COG2002@2|Bacteria,1V3PE@1239|Firmicutes,24IQG@186801|Clostridia	186801|Clostridia	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02969	622312.ROSEINA2194_02328	4.65e-58	180.0	COG2002@1|root,COG2002@2|Bacteria,1VB2K@1239|Firmicutes,24RSN@186801|Clostridia	186801|Clostridia	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02970	622312.ROSEINA2194_02329	7.94e-54	168.0	2CDYZ@1|root,3459B@2|Bacteria,1VZ76@1239|Firmicutes,2533N@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02971	622312.ROSEINA2194_02330	5.74e-112	322.0	2DMZM@1|root,32UMJ@2|Bacteria	2|Bacteria	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	YodL
KFPFDFKC_02972	622312.ROSEINA2194_02331	8.38e-67	204.0	COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,24MVQ@186801|Clostridia	186801|Clostridia	D	Could be involved in septation	spoVG1	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
KFPFDFKC_02973	622312.ROSEINA2194_02332	1.07e-43	142.0	2E4MF@1|root,32ZGD@2|Bacteria,1VEIK@1239|Firmicutes,24QUQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02974	622312.ROSEINA2194_02333	1.57e-83	248.0	COG2088@1|root,COG2088@2|Bacteria,1VYH3@1239|Firmicutes,253N0@186801|Clostridia	186801|Clostridia	M	SpoVG	-	-	-	-	-	-	-	-	-	-	-	-	SpoVG
KFPFDFKC_02975	622312.ROSEINA2194_02334	3.66e-75	226.0	COG1989@1|root,COG1989@2|Bacteria	2|Bacteria	NOU	aspartic-type endopeptidase activity	gspO	-	3.4.23.43	ko:K02278,ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
KFPFDFKC_02976	622312.ROSEINA2194_01294	1.65e-183	512.0	COG3745@1|root,COG3745@2|Bacteria,1TQRH@1239|Firmicutes,24BZT@186801|Clostridia	186801|Clostridia	U	Flp pilus assembly protein CpaB	cpaB	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
KFPFDFKC_02977	397291.C804_05703	1.11e-147	421.0	COG0455@1|root,COG0455@2|Bacteria,1TPJA@1239|Firmicutes,24A7K@186801|Clostridia	186801|Clostridia	D	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA
KFPFDFKC_02978	622312.ROSEINA2194_01291	0.0	890.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia	186801|Clostridia	U	Type II IV secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
KFPFDFKC_02979	397291.C804_05705	9.18e-183	513.0	COG4965@1|root,COG4965@2|Bacteria,1TS4U@1239|Firmicutes,248K2@186801|Clostridia	186801|Clostridia	U	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02980	622312.ROSEINA2194_01288	4.76e-172	483.0	COG2064@1|root,COG2064@2|Bacteria,1TUMZ@1239|Firmicutes,2495N@186801|Clostridia	186801|Clostridia	NU	Psort location CytoplasmicMembrane, score	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	-
KFPFDFKC_02981	622312.ROSEINA2194_01287	7.59e-89	261.0	2C3VQ@1|root,2ZQ9I@2|Bacteria,1V3RW@1239|Firmicutes,24HQ0@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4320
KFPFDFKC_02982	622312.ROSEINA2194_01286	5.61e-121	346.0	28MX7@1|root,2ZB4B@2|Bacteria,1UYA5@1239|Firmicutes,24F22@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02983	622312.ROSEINA2194_01285	6.99e-94	277.0	28MSI@1|root,2ZB0V@2|Bacteria,1UZDN@1239|Firmicutes,24NJ1@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02985	622312.ROSEINA2194_01282	0.0	1075.0	COG1572@1|root,COG1572@2|Bacteria,1TR48@1239|Firmicutes,24ADC@186801|Clostridia	186801|Clostridia	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02986	622312.ROSEINA2194_01281	8.4e-112	320.0	28J4N@1|root,2Z90I@2|Bacteria,1V0D6@1239|Firmicutes,24HMY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02987	622312.ROSEINA2194_01280	1.08e-73	221.0	2B05D@1|root,31SFX@2|Bacteria,1V79U@1239|Firmicutes,24KBJ@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3852
KFPFDFKC_02988	622312.ROSEINA2194_01279	3.69e-198	550.0	28I46@1|root,2Z87R@2|Bacteria,1TQ13@1239|Firmicutes,249S3@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02989	622312.ROSEINA2194_01278	0.0	934.0	COG0270@1|root,COG0270@2|Bacteria,1TR36@1239|Firmicutes,249XY@186801|Clostridia	1239|Firmicutes	L	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
KFPFDFKC_02990	622312.ROSEINA2194_01277	5.51e-60	184.0	2BXEN@1|root,32R17@2|Bacteria,1V7Y8@1239|Firmicutes,24SE0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02991	622312.ROSEINA2194_01276	6.74e-126	359.0	28HKG@1|root,2Z7VB@2|Bacteria,1TZFI@1239|Firmicutes,24BXG@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02992	397291.C804_05719	0.0	1129.0	COG3451@1|root,COG3451@2|Bacteria,1TS2J@1239|Firmicutes,25EI6@186801|Clostridia,27IJC@186928|unclassified Lachnospiraceae	186801|Clostridia	U	Domain of unknown function DUF87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87
KFPFDFKC_02993	622312.ROSEINA2194_01273	3.46e-241	663.0	28HR1@1|root,2Z7YI@2|Bacteria,1TRNR@1239|Firmicutes,2486X@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Amidoligase_2
KFPFDFKC_02994	622312.ROSEINA2194_01272	1.93e-117	336.0	COG2105@1|root,COG2105@2|Bacteria,1VDAD@1239|Firmicutes,24G9Y@186801|Clostridia	186801|Clostridia	S	PFAM AIG2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
KFPFDFKC_02995	622312.ROSEINA2194_01271	1.52e-262	719.0	COG0791@1|root,COG0791@2|Bacteria,1UJUQ@1239|Firmicutes,25FAF@186801|Clostridia	186801|Clostridia	M	NlpC p60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
KFPFDFKC_02996	622312.ROSEINA2194_01270	4.66e-66	202.0	2EA8K@1|root,334D3@2|Bacteria,1VD6U@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02997	622312.ROSEINA2194_01269	1.3e-164	459.0	28PM6@1|root,346EC@2|Bacteria,1W146@1239|Firmicutes,2534I@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02998	397291.C804_05728	1.83e-34	119.0	2EA8K@1|root,330PF@2|Bacteria,1VFGQ@1239|Firmicutes,24T8A@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_02999	622312.ROSEINA2194_01266	1.67e-83	246.0	COG4734@1|root,COG4734@2|Bacteria,1VCQ0@1239|Firmicutes,24PDW@186801|Clostridia	186801|Clostridia	L	Domain of unknown function (DUF3846)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3846
KFPFDFKC_03000	411483.FAEPRAA2165_00066	9.38e-25	95.1	2AZMT@1|root,31RWJ@2|Bacteria,1V7QQ@1239|Firmicutes,25CZU@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03001	411483.FAEPRAA2165_00067	3.76e-121	347.0	COG1595@1|root,COG1595@2|Bacteria,1UZ1M@1239|Firmicutes,24AUS@186801|Clostridia,3WK65@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
KFPFDFKC_03002	585394.RHOM_16320	2.62e-180	504.0	28J53@1|root,2Z90Z@2|Bacteria,1UZB1@1239|Firmicutes,24EGW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03005	1256908.HMPREF0373_00590	9.07e-143	403.0	2DD90@1|root,2ZH3Q@2|Bacteria,1V1HB@1239|Firmicutes,24GNM@186801|Clostridia,25YGQ@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function, E. rectale Gene description (DUF3879)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3879
KFPFDFKC_03006	622312.ROSEINA2194_01263	7.4e-72	218.0	297FF@1|root,2ZCG2@2|Bacteria,1V2VZ@1239|Firmicutes,24GYA@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03007	1235790.C805_02339	5.04e-06	47.4	2EK1N@1|root,33DS4@2|Bacteria,1VK49@1239|Firmicutes,252AT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03008	658086.HMPREF0994_01287	2.45e-41	141.0	COG1848@1|root,COG1848@2|Bacteria,1VCDC@1239|Firmicutes,24P6P@186801|Clostridia,27UGP@186928|unclassified Lachnospiraceae	186801|Clostridia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
KFPFDFKC_03009	742733.HMPREF9469_02685	2.35e-65	211.0	COG4804@1|root,COG4804@2|Bacteria,1TP7Q@1239|Firmicutes,24A19@186801|Clostridia,21ZRE@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
KFPFDFKC_03010	585394.RHOM_12965	1.99e-69	209.0	2CABA@1|root,32ZBQ@2|Bacteria,1VFWB@1239|Firmicutes,24RY5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03011	1282887.AUJG01000017_gene1243	1.22e-108	315.0	2C4YS@1|root,32RET@2|Bacteria,1V2W0@1239|Firmicutes,24H32@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03013	608534.GCWU000341_00935	6.72e-86	257.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
KFPFDFKC_03014	1235793.C809_02288	5.5e-34	117.0	2E5UB@1|root,330IM@2|Bacteria,1VFEC@1239|Firmicutes,24UNV@186801|Clostridia,27Q7G@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03015	1235793.C809_02289	2.71e-239	660.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,27IQ7@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
KFPFDFKC_03016	552396.HMPREF0863_01960	5.93e-12	64.7	2C05I@1|root,2ZE0I@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03017	1235793.C809_02291	1.24e-91	274.0	COG0358@1|root,COG0358@2|Bacteria,1UZ28@1239|Firmicutes,248N2@186801|Clostridia,27PAG@186928|unclassified Lachnospiraceae	186801|Clostridia	L	CHC2 zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHC2
KFPFDFKC_03018	592026.GCWU0000282_001327	1.46e-252	701.0	COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,2495S@186801|Clostridia	186801|Clostridia	L	Virulence-associated protein E	-	-	-	-	-	-	-	-	-	-	-	-	VirE
KFPFDFKC_03019	1235793.C809_02293	2.62e-148	426.0	2DB8G@1|root,2Z7RT@2|Bacteria,1US26@1239|Firmicutes,24B9G@186801|Clostridia,27TVP@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03020	397291.C804_06297	4.98e-22	92.4	29GWR@1|root,303UG@2|Bacteria,1TV9N@1239|Firmicutes,25A3B@186801|Clostridia,27PM3@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03022	1235793.C809_02295	2.14e-155	452.0	COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia,27K2X@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
KFPFDFKC_03023	1235793.C809_02296	5.09e-55	174.0	2DMY9@1|root,32UCT@2|Bacteria,1VAN7@1239|Firmicutes,24PHY@186801|Clostridia,27P1D@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
KFPFDFKC_03024	1235799.C818_01801	7.31e-106	309.0	COG1961@1|root,COG1961@2|Bacteria,1TQAX@1239|Firmicutes,24B05@186801|Clostridia,27M9D@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
KFPFDFKC_03025	1408324.JNJK01000008_gene1732	8.06e-139	401.0	COG1002@1|root,COG1002@2|Bacteria,1TT83@1239|Firmicutes,248CV@186801|Clostridia,27QT4@186928|unclassified Lachnospiraceae	186801|Clostridia	V	restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I
KFPFDFKC_03026	411483.FAEPRAA2165_01493	2.32e-158	465.0	COG0286@1|root,COG1002@1|root,COG0286@2|Bacteria,COG1002@2|Bacteria,1TT83@1239|Firmicutes,248CV@186801|Clostridia,3WIQA@541000|Ruminococcaceae	186801|Clostridia	L	restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I
KFPFDFKC_03027	907348.TresaDRAFT_2301	0.0	1530.0	COG1061@1|root,COG1061@2|Bacteria	2|Bacteria	L	Type III restriction enzyme res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,ResIII,T5orf172
KFPFDFKC_03028	665950.HMPREF1025_00004	1.11e-242	709.0	COG0507@1|root,COG0515@1|root,COG0507@2|Bacteria,COG0515@2|Bacteria,1VW06@1239|Firmicutes	1239|Firmicutes	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11
KFPFDFKC_03029	1123288.SOV_2c07040	1.24e-58	205.0	2F4WZ@1|root,33XJ2@2|Bacteria,1VVTM@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03030	350688.Clos_1301	9.24e-65	206.0	2FF0M@1|root,346Z2@2|Bacteria,1VZ03@1239|Firmicutes,252TW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03032	585394.RHOM_05165	7.22e-238	654.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia	186801|Clostridia	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
KFPFDFKC_03033	585394.RHOM_05170	3.91e-270	742.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia	186801|Clostridia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
KFPFDFKC_03034	585394.RHOM_05175	2.9e-172	481.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS19265	TIM
KFPFDFKC_03036	585394.RHOM_05185	0.0	954.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
KFPFDFKC_03037	585394.RHOM_05190	2.44e-190	531.0	COG0152@1|root,COG0152@2|Bacteria	2|Bacteria	F	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6,6.3.4.13	ko:K01923,ko:K01945,ko:K03566	ko00230,ko01100,ko01110,ko01130,ko02026,map00230,map01100,map01110,map01130,map02026	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	SAICAR_synt
KFPFDFKC_03038	585394.RHOM_05195	0.0	893.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
KFPFDFKC_03039	622312.ROSEINA2194_03091	0.0	899.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
KFPFDFKC_03040	622312.ROSEINA2194_00711	5.08e-262	719.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia	186801|Clostridia	C	alcohol dehydrogenase	fucO	-	1.1.1.77	ko:K00048	ko00630,ko00640,ko01120,map00630,map00640,map01120	-	R01781,R02257	RC00087,RC00099	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
KFPFDFKC_03041	622312.ROSEINA2194_04423	8.18e-101	295.0	COG1309@1|root,COG1309@2|Bacteria,1U1ZX@1239|Firmicutes,24ERU@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
KFPFDFKC_03042	585394.RHOM_06020	0.0	917.0	COG1070@1|root,COG1070@2|Bacteria,1TP91@1239|Firmicutes,24A4Z@186801|Clostridia	186801|Clostridia	G	Carbohydrate kinase, FGGY family protein	araB	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
KFPFDFKC_03043	585394.RHOM_06025	0.0	966.0	COG2160@1|root,COG2160@2|Bacteria,1TPXC@1239|Firmicutes,24A08@186801|Clostridia	186801|Clostridia	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
KFPFDFKC_03044	585394.RHOM_06035	8.34e-147	414.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia	186801|Clostridia	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
KFPFDFKC_03045	1410612.JNKO01000001_gene2727	7.57e-167	470.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,2PTU7@265975|Oribacterium	186801|Clostridia	G	Dehydrogenase E1 component	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
KFPFDFKC_03046	585394.RHOM_06045	1.82e-189	530.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia	186801|Clostridia	G	Transketolase	tktB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
KFPFDFKC_03047	585394.RHOM_06050	1.63e-169	473.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia	186801|Clostridia	G	L-ribulose-5-phosphate 4-epimerase	ulaF	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
KFPFDFKC_03048	585394.RHOM_06055	1.45e-175	498.0	COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,249DZ@186801|Clostridia	186801|Clostridia	G	Converts alpha-aldose to the beta-anomer	mro	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
KFPFDFKC_03049	622312.ROSEINA2194_04149	2.02e-227	648.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
KFPFDFKC_03050	742765.HMPREF9457_02438	0.0	958.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,248VT@186801|Clostridia,27WFN@189330|Dorea	186801|Clostridia	U	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
KFPFDFKC_03051	1121115.AXVN01000176_gene3754	8.37e-42	137.0	COG3655@1|root,COG3655@2|Bacteria,1VEM0@1239|Firmicutes,24QPN@186801|Clostridia,3Y0TA@572511|Blautia	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
KFPFDFKC_03052	411470.RUMGNA_01134	9.52e-74	221.0	COG2963@1|root,COG2963@2|Bacteria,1VE6Y@1239|Firmicutes,25BJ2@186801|Clostridia	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
KFPFDFKC_03053	411470.RUMGNA_01135	1.05e-203	563.0	COG2801@1|root,COG2801@2|Bacteria,1TRNK@1239|Firmicutes,24B7I@186801|Clostridia,3Y0HR@572511|Blautia	186801|Clostridia	L	COG COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve
KFPFDFKC_03054	562982.HMPREF0432_00430	1.28e-173	484.0	COG0030@1|root,COG0030@2|Bacteria,1UY9S@1239|Firmicutes,4HC16@91061|Bacilli	91061|Bacilli	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family	ermA	-	2.1.1.184	ko:K00561	-	-	R10716	RC00003,RC03257	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	RrnaAD
KFPFDFKC_03055	1158604.I591_02847	2.19e-16	70.9	2A8RU@1|root,30XUI@2|Bacteria,1VHZC@1239|Firmicutes,4IBX8@91061|Bacilli,4B49K@81852|Enterococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03056	565653.EGBG_00002	4.1e-25	96.7	29K9A@1|root,3076M@2|Bacteria,1U14H@1239|Firmicutes,4IAKD@91061|Bacilli,4B5N1@81852|Enterococcaceae	91061|Bacilli	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
KFPFDFKC_03057	1449338.JQLU01000001_gene928	0.0	975.0	COG1959@1|root,COG1959@2|Bacteria,1UBUD@1239|Firmicutes,4HB0A@91061|Bacilli,27H8Y@186828|Carnobacteriaceae	91061|Bacilli	K	Primase C terminal 1 (PriCT-1)	repE	-	-	-	-	-	-	-	-	-	-	-	PriCT_1
KFPFDFKC_03058	1234679.BN424_1079	2.14e-279	764.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HB0P@91061|Bacilli,27FPR@186828|Carnobacteriaceae	91061|Bacilli	L	L COG3328 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
KFPFDFKC_03059	1280.SAXN108_2178	2.09e-95	277.0	COG0454@1|root,COG0456@2|Bacteria,1TXSN@1239|Firmicutes,4I6UP@91061|Bacilli,4GZ1F@90964|Staphylococcaceae	91061|Bacilli	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
KFPFDFKC_03060	1232666.JANE01000006_gene1918	1.7e-148	429.0	COG1670@1|root,COG3173@1|root,COG1670@2|Bacteria,COG3173@2|Bacteria,1V1G0@1239|Firmicutes,4I3EZ@91061|Bacilli,4GYHN@90964|Staphylococcaceae	91061|Bacilli	F	Involved in resistance to gentamicin, tobramycin, and kanamycin. Tobramycin and kanamycin resistance is due to the ACC activity, specified by N-terminal region. The C-terminal region is a kinase that phosphorylates several 4,6-disubstituted aminoglycosides	-	-	2.3.1.82,2.7.1.190	ko:K19883	-	-	R11229	RC00002,RC00078	ko00000,ko01000,ko01504	-	-	-	APH,Acetyltransf_8
KFPFDFKC_03061	658086.HMPREF0994_00106	2.07e-104	328.0	COG1431@1|root,COG1431@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Piwi,SIR2_2
KFPFDFKC_03062	411459.RUMOBE_01589	1.36e-20	89.0	2CJF3@1|root,30DZI@2|Bacteria,1V3V7@1239|Firmicutes,24IC0@186801|Clostridia,3Y0SF@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03063	1256908.HMPREF0373_03413	1.1e-144	448.0	COG5290@1|root,COG5290@2|Bacteria,1TQYD@1239|Firmicutes,24F3J@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03064	1256908.HMPREF0373_03413	1.87e-81	276.0	COG5290@1|root,COG5290@2|Bacteria,1TQYD@1239|Firmicutes,24F3J@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03065	478749.BRYFOR_05201	3.07e-128	377.0	COG4861@1|root,COG4861@2|Bacteria,1VU1D@1239|Firmicutes,24XTR@186801|Clostridia	186801|Clostridia	S	Transcriptional regulator, AbiEi antitoxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_2
KFPFDFKC_03066	1408311.JNJM01000015_gene2627	2.41e-150	428.0	28K5X@1|root,2Z9UF@2|Bacteria,1VQ61@1239|Firmicutes,24YVC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03067	411463.EUBVEN_01879	2.5e-52	165.0	2ER6I@1|root,33IS5@2|Bacteria,1VMUP@1239|Firmicutes,24TIH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03068	500632.CLONEX_00889	3.29e-82	243.0	29XM1@1|root,30JC9@2|Bacteria,1V5MS@1239|Firmicutes,24I25@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03069	938289.CAJN020000001_gene1164	8.42e-115	329.0	COG1396@1|root,COG1396@2|Bacteria,1V1JY@1239|Firmicutes,24HXG@186801|Clostridia,26B2Y@186813|unclassified Clostridiales	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
KFPFDFKC_03070	428125.CLOLEP_03211	6.81e-34	116.0	2E5UB@1|root,330IM@2|Bacteria,1VFEC@1239|Firmicutes,24R3P@186801|Clostridia,3WM8N@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03071	938289.CAJN020000001_gene1165	9.56e-267	729.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,2689P@186813|unclassified Clostridiales	186801|Clostridia	L	Site-specific recombinase, phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
KFPFDFKC_03072	411460.RUMTOR_02161	1.43e-64	197.0	2AQJ5@1|root,31FRY@2|Bacteria,1V6TG@1239|Firmicutes,25MZ5@186801|Clostridia,3Y0P8@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03073	478749.BRYFOR_06470	4.53e-245	676.0	COG3598@1|root,COG3598@2|Bacteria,1TU5N@1239|Firmicutes,247KK@186801|Clostridia	186801|Clostridia	L	COG NOG19743 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,PriCT_1,Prim-Pol
KFPFDFKC_03074	428125.CLOLEP_03219	6.18e-201	565.0	COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia,3WHRE@541000|Ruminococcaceae	186801|Clostridia	M	plasmid recombination	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
KFPFDFKC_03075	938289.CAJN020000001_gene1169	1.3e-87	257.0	2C5R4@1|root,2ZC1N@2|Bacteria,1V292@1239|Firmicutes,24IHH@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
KFPFDFKC_03076	397287.C807_02474	7.16e-118	340.0	COG2801@1|root,COG2801@2|Bacteria,1TPEH@1239|Firmicutes,24DNX@186801|Clostridia,27T8M@186928|unclassified Lachnospiraceae	186801|Clostridia	L	DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
KFPFDFKC_03077	397287.C807_02475	1.86e-54	171.0	COG2963@1|root,COG2963@2|Bacteria,1V9ZX@1239|Firmicutes,24P3X@186801|Clostridia,27RZY@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
KFPFDFKC_03080	469604.HMPREF0946_01273	1.35e-68	212.0	COG3600@1|root,COG3600@2|Bacteria,37CFS@32066|Fusobacteria	32066|Fusobacteria	S	Protein of unknown function (DUF4065)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4065
KFPFDFKC_03081	585394.RHOM_11965	9.96e-20	84.7	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
KFPFDFKC_03082	1280698.AUJS01000007_gene1002	7.22e-19	85.9	COG1396@1|root,COG1396@2|Bacteria,1VEU8@1239|Firmicutes,24QN0@186801|Clostridia,27VXX@189330|Dorea	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
KFPFDFKC_03083	1235793.C809_02624	0.0	896.0	COG1961@1|root,COG1961@2|Bacteria,1TS5B@1239|Firmicutes,248MZ@186801|Clostridia,27KAN@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
KFPFDFKC_03087	585394.RHOM_08305	1e-16	79.7	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
KFPFDFKC_03088	585394.RHOM_08310	5.53e-242	672.0	COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,248NX@186801|Clostridia	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
KFPFDFKC_03089	622312.ROSEINA2194_00521	1.14e-46	158.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,24N7H@186801|Clostridia	186801|Clostridia	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	fthC	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
KFPFDFKC_03090	585394.RHOM_08320	1.5e-31	111.0	COG4224@1|root,COG4224@2|Bacteria,1TUAX@1239|Firmicutes,24QS9@186801|Clostridia	186801|Clostridia	S	UPF0291 protein	ynzC	-	-	-	-	-	-	-	-	-	-	-	DUF896
KFPFDFKC_03091	585394.RHOM_08325	5.11e-183	511.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,2486P@186801|Clostridia	186801|Clostridia	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
KFPFDFKC_03092	585394.RHOM_08330	1.53e-172	490.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
KFPFDFKC_03093	585394.RHOM_04115	2.77e-238	663.0	COG5434@1|root,COG5434@2|Bacteria,1TRWY@1239|Firmicutes,24DY3@186801|Clostridia	186801|Clostridia	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03095	585394.RHOM_04105	1.84e-157	445.0	COG0395@1|root,COG0395@2|Bacteria,1TSGI@1239|Firmicutes,24BDH@186801|Clostridia	186801|Clostridia	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10190	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	BPD_transp_1
KFPFDFKC_03096	585394.RHOM_04100	2.41e-170	480.0	COG1175@1|root,COG1175@2|Bacteria,1TPMR@1239|Firmicutes,2494U@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K10189	ko02010,map02010	M00199,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.4	-	-	BPD_transp_1
KFPFDFKC_03097	585394.RHOM_04095	2.93e-242	675.0	COG1653@1|root,COG1653@2|Bacteria,1TQ0V@1239|Firmicutes,2481M@186801|Clostridia	186801|Clostridia	G	solute-binding protein	-	-	-	ko:K10188	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	SBP_bac_1,SBP_bac_8
KFPFDFKC_03098	397287.C807_03129	0.0	1235.0	COG5426@1|root,COG5426@2|Bacteria,1TPH0@1239|Firmicutes,24892@186801|Clostridia,27J14@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Lacto-N-biose phosphorylase C-terminal domain	-	-	2.4.1.211	ko:K15533	-	-	-	-	ko00000,ko01000	-	-	-	LBP_C,LBP_M,Lact_bio_phlase
KFPFDFKC_03099	1469948.JPNB01000002_gene2888	6.5e-38	135.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1TQ2W@1239|Firmicutes,24A5W@186801|Clostridia,36VIU@31979|Clostridiaceae	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
KFPFDFKC_03100	585394.RHOM_00965	1.57e-70	214.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
KFPFDFKC_03101	585394.RHOM_00960	7.98e-105	305.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
KFPFDFKC_03102	622312.ROSEINA2194_01982	7.27e-157	441.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
KFPFDFKC_03103	397290.C810_03360	9.01e-89	261.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,27M6H@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
KFPFDFKC_03104	585394.RHOM_00945	3.44e-117	335.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia	186801|Clostridia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
KFPFDFKC_03105	140626.JHWB01000009_gene1219	2.28e-27	100.0	COG0690@1|root,COG0690@2|Bacteria,1VH7Y@1239|Firmicutes,24RJ1@186801|Clostridia	186801|Clostridia	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
KFPFDFKC_03106	585394.RHOM_00930	1.46e-160	467.0	COG1345@1|root,COG1345@2|Bacteria,1U3CE@1239|Firmicutes,24B6P@186801|Clostridia	186801|Clostridia	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliD_C,FliD_N
KFPFDFKC_03107	585394.RHOM_00925	1.04e-244	677.0	COG4641@1|root,COG4641@2|Bacteria,1TR7G@1239|Firmicutes,24ATN@186801|Clostridia	186801|Clostridia	S	DUF based on E. rectale Gene description (DUF3880)	-	-	-	ko:K06320	-	-	-	-	ko00000	-	-	-	DUF3880,Glyco_trans_1_2
KFPFDFKC_03108	585394.RHOM_00920	6.02e-221	618.0	COG4641@1|root,COG4641@2|Bacteria,1V0EG@1239|Firmicutes,24DZB@186801|Clostridia	186801|Clostridia	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
KFPFDFKC_03109	622312.ROSEINA2194_00427	1.22e-279	776.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
KFPFDFKC_03110	585394.RHOM_00900	4.58e-169	484.0	COG0457@1|root,COG0463@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,1TSF5@1239|Firmicutes,25B5G@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2,TPR_2,TPR_7,TPR_8
KFPFDFKC_03111	622312.ROSEINA2194_00426	0.0	876.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
KFPFDFKC_03112	622312.ROSEINA2194_00406	2.93e-170	483.0	COG1215@1|root,COG1215@2|Bacteria,1UMA5@1239|Firmicutes,25GD8@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
KFPFDFKC_03113	622312.ROSEINA2194_02511	3.39e-214	601.0	COG0615@1|root,COG2513@1|root,COG0615@2|Bacteria,COG2513@2|Bacteria,1TQVY@1239|Firmicutes,24AC5@186801|Clostridia	186801|Clostridia	GM	phosphoenolpyruvate	aepX	-	5.4.2.9	ko:K01841	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	-	R00661	RC02792	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like,NTP_transf_3,PEP_mutase
KFPFDFKC_03114	1408304.JAHA01000010_gene170	1.5e-08	54.7	COG0615@1|root,COG2513@1|root,COG0615@2|Bacteria,COG2513@2|Bacteria,1TQVY@1239|Firmicutes,24AC5@186801|Clostridia,4BW3D@830|Butyrivibrio	186801|Clostridia	GIM	Phosphoenolpyruvate phosphomutase	aepX	-	5.4.2.9	ko:K01841	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	-	R00661	RC02792	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like,NTP_transf_3,PEP_mutase
KFPFDFKC_03115	1280692.AUJL01000001_gene306	3.3e-148	431.0	COG0028@1|root,COG0028@2|Bacteria,1TSJZ@1239|Firmicutes,24AIU@186801|Clostridia,36F1Y@31979|Clostridiaceae	186801|Clostridia	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	aepY	-	4.1.1.82	ko:K09459	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	-	R04053	RC00506	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
KFPFDFKC_03116	397287.C807_02814	4.77e-52	172.0	COG4750@1|root,COG4750@2|Bacteria,1UYW1@1239|Firmicutes,25CE0@186801|Clostridia,27M9E@186928|unclassified Lachnospiraceae	186801|Clostridia	M	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	APH,HTH_24,NTP_transf_3,NTP_transferase
KFPFDFKC_03117	397287.C807_02814	4.28e-33	121.0	COG4750@1|root,COG4750@2|Bacteria,1UYW1@1239|Firmicutes,25CE0@186801|Clostridia,27M9E@186928|unclassified Lachnospiraceae	186801|Clostridia	M	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	APH,HTH_24,NTP_transf_3,NTP_transferase
KFPFDFKC_03118	397287.C807_02815	6.2e-215	600.0	COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,24919@186801|Clostridia,27IRA@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily	phnW	-	2.6.1.37,3.11.1.1	ko:K03430,ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	-	R00747,R04152	RC00008,RC00062,RC00368	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_5,HAD_2
KFPFDFKC_03120	483218.BACPEC_00104	3.18e-210	582.0	2BZ87@1|root,2ZAPT@2|Bacteria,1U7MJ@1239|Firmicutes,24B9C@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03121	1256908.HMPREF0373_00348	1.14e-228	629.0	28K66@1|root,2Z9UP@2|Bacteria,1UYD9@1239|Firmicutes,24END@186801|Clostridia,25YVJ@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03122	1256908.HMPREF0373_00347	1.8e-165	464.0	29JMI@1|root,306IV@2|Bacteria,1V3QS@1239|Firmicutes,24HXQ@186801|Clostridia,25XVM@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03123	585394.RHOM_12555	1.53e-135	388.0	290WF@1|root,2ZNI9@2|Bacteria,1V2CA@1239|Firmicutes,24GXX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03124	1256908.HMPREF0373_00354	4.74e-212	586.0	2C3TV@1|root,2Z8B0@2|Bacteria,1V075@1239|Firmicutes,24CC4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03125	1256908.HMPREF0373_00355	4.77e-220	607.0	2DBH1@1|root,2Z96X@2|Bacteria,1UY05@1239|Firmicutes,24ABQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03126	585394.RHOM_12555	2.43e-125	362.0	290WF@1|root,2ZNI9@2|Bacteria,1V2CA@1239|Firmicutes,24GXX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03127	511680.BUTYVIB_02361	2.03e-144	408.0	290UV@1|root,2ZNGV@2|Bacteria,1V2HB@1239|Firmicutes,24GF7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03128	515620.EUBELI_20004	1.19e-101	295.0	2E7F0@1|root,331Y0@2|Bacteria,1VEPY@1239|Firmicutes,24TMW@186801|Clostridia,25YNM@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03129	1235800.C819_02869	3.15e-301	830.0	28RNQ@1|root,2ZE1D@2|Bacteria,1V1HU@1239|Firmicutes,24GGJ@186801|Clostridia,27JX3@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03130	515620.EUBELI_20004	8.31e-20	83.6	2E7F0@1|root,331Y0@2|Bacteria,1VEPY@1239|Firmicutes,24TMW@186801|Clostridia,25YNM@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03132	483218.BACPEC_01804	1.58e-75	226.0	COG1396@1|root,COG1396@2|Bacteria,1UKPK@1239|Firmicutes,25G0R@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03133	483218.BACPEC_01805	1.05e-97	285.0	COG1595@1|root,COG1595@2|Bacteria,1V22M@1239|Firmicutes,24EDG@186801|Clostridia,269K8@186813|unclassified Clostridiales	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4,Sigma70_r4_2
KFPFDFKC_03134	483218.BACPEC_01806	1.36e-42	139.0	2AJW5@1|root,3321D@2|Bacteria,1VFNY@1239|Firmicutes,24RSP@186801|Clostridia,269TA@186813|unclassified Clostridiales	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
KFPFDFKC_03135	483218.BACPEC_01807	6.68e-35	119.0	2E3CH@1|root,32YBT@2|Bacteria,1VHJT@1239|Firmicutes,24PVI@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03136	483218.BACPEC_01809	1.46e-33	115.0	2E7G7@1|root,331Z1@2|Bacteria,1VIY2@1239|Firmicutes,24SF1@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03137	483218.BACPEC_01810	5.52e-305	830.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,26AIQ@186813|unclassified Clostridiales	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_3,Phage_integrase
KFPFDFKC_03138	665950.HMPREF1025_02922	3.52e-273	748.0	COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,247ME@186801|Clostridia,27IGQ@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
KFPFDFKC_03139	622312.ROSEINA2194_03927	4.33e-155	465.0	COG3501@1|root,COG3501@2|Bacteria,1V3I5@1239|Firmicutes,24GKG@186801|Clostridia	186801|Clostridia	F	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
KFPFDFKC_03140	622312.ROSEINA2194_03556	1.96e-51	167.0	COG3501@1|root,COG3501@2|Bacteria	2|Bacteria	T	Rhs element vgr protein	-	-	-	ko:K10953	ko05110,map05110	-	-	-	ko00000,ko00001,ko02042	-	-	-	DUF4781,Phage_GPD,RHS_repeat
KFPFDFKC_03141	622312.ROSEINA2194_01632	6.94e-75	230.0	COG3209@1|root,COG3209@2|Bacteria,1VWD3@1239|Firmicutes	1239|Firmicutes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS,RHS_repeat
KFPFDFKC_03142	622312.ROSEINA2194_01631	4.38e-146	411.0	28YG2@1|root,2ZKAC@2|Bacteria,1VNA1@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1963
KFPFDFKC_03143	622312.ROSEINA2194_03927	5.2e-83	266.0	COG3501@1|root,COG3501@2|Bacteria,1V3I5@1239|Firmicutes,24GKG@186801|Clostridia	186801|Clostridia	F	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
KFPFDFKC_03144	1117108.PAALTS15_03472	7.66e-96	284.0	2EZAX@1|root,33SGC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03145	585394.RHOM_15055	9.02e-29	107.0	COG1943@1|root,COG1943@2|Bacteria,1V9QQ@1239|Firmicutes,24K68@186801|Clostridia	186801|Clostridia	L	COG1943 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
KFPFDFKC_03146	622312.ROSEINA2194_01632	2.27e-97	294.0	COG3209@1|root,COG3209@2|Bacteria,1VWD3@1239|Firmicutes	1239|Firmicutes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS,RHS_repeat
KFPFDFKC_03148	622312.ROSEINA2194_01630	5.96e-57	187.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	RHS,RHS_repeat
KFPFDFKC_03149	665950.HMPREF1025_01293	4.51e-277	764.0	COG3385@1|root,COG3385@2|Bacteria,1TSH6@1239|Firmicutes,24A21@186801|Clostridia,27JSZ@186928|unclassified Lachnospiraceae	186801|Clostridia	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
KFPFDFKC_03150	1285586.H131_00990	3.03e-70	218.0	2EISZ@1|root,33CIA@2|Bacteria,1VQG5@1239|Firmicutes,4HVKT@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03151	622312.ROSEINA2194_01633	9.22e-66	211.0	COG3209@1|root,COG3209@2|Bacteria,1V5PZ@1239|Firmicutes	1239|Firmicutes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS,RHS_repeat
KFPFDFKC_03152	1410638.JHXJ01000001_gene1725	1.16e-101	299.0	COG0286@1|root,COG0286@2|Bacteria,1V60T@1239|Firmicutes,24I05@186801|Clostridia,3WMIZ@541000|Ruminococcaceae	186801|Clostridia	V	site-specific DNA-methyltransferase (adenine-specific) activity	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03153	622312.ROSEINA2194_04022	5.84e-71	223.0	COG3385@1|root,COG3385@2|Bacteria,1TSH6@1239|Firmicutes,24A21@186801|Clostridia	186801|Clostridia	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
KFPFDFKC_03154	622312.ROSEINA2194_01398	6.12e-121	348.0	COG5620@1|root,COG5620@2|Bacteria,1V5S8@1239|Firmicutes,24K3Z@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF1851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1851,GAD-like
KFPFDFKC_03155	1450694.BTS2_2012	4.39e-62	209.0	COG5585@1|root,COG5585@2|Bacteria,1V069@1239|Firmicutes,4HD0D@91061|Bacilli,1ZE7A@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ADPrib_exo_Tox,PT-TG
KFPFDFKC_03156	585394.RHOM_00445	7.19e-49	159.0	2DPVJ@1|root,333JK@2|Bacteria,1VGI4@1239|Firmicutes,24R70@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DZR,zinc_ribbon_2
KFPFDFKC_03157	585394.RHOM_00450	2.84e-159	466.0	2A7KX@1|root,30WIW@2|Bacteria,1V536@1239|Firmicutes,24J38@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03158	622312.ROSEINA2194_01741	1.28e-103	304.0	COG2755@1|root,COG2755@2|Bacteria,1V3A9@1239|Firmicutes,24FYQ@186801|Clostridia	186801|Clostridia	E	COG2755 Lysophospholipase L1 and related esterases	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
KFPFDFKC_03160	1280698.AUJS01000028_gene2292	8.95e-102	298.0	COG1954@1|root,COG1954@2|Bacteria,1V4IE@1239|Firmicutes,24HDM@186801|Clostridia,27VYY@189330|Dorea	186801|Clostridia	K	Glycerol-3-phosphate responsive antiterminator	glpP	-	-	ko:K02443	-	-	-	-	ko00000,ko03000	-	-	-	G3P_antiterm
KFPFDFKC_03161	411462.DORLON_02611	0.0	989.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,27V84@189330|Dorea	186801|Clostridia	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
KFPFDFKC_03162	411462.DORLON_02610	3.47e-153	432.0	COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,248U5@186801|Clostridia	186801|Clostridia	G	Belongs to the MIP aquaporin (TC 1.A.8) family	glpF	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
KFPFDFKC_03163	411462.DORLON_02609	2.29e-298	819.0	COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,27V95@189330|Dorea	186801|Clostridia	S	BFD-like [2Fe-2S] binding domain	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
KFPFDFKC_03164	411462.DORLON_02608	1.3e-273	752.0	COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia,27UZQ@189330|Dorea	186801|Clostridia	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_3
KFPFDFKC_03165	411462.DORLON_02607	1.32e-65	201.0	COG3862@1|root,COG3862@2|Bacteria,1VA4U@1239|Firmicutes,24MN9@186801|Clostridia,27VRH@189330|Dorea	186801|Clostridia	S	Protein of unknown function (DUF1667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1667
KFPFDFKC_03166	1340434.AXVA01000004_gene2641	2.79e-06	58.5	COG1653@1|root,COG3757@1|root,COG4733@1|root,COG1653@2|Bacteria,COG3757@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	lyc	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.2.1.17,3.2.1.8	ko:K01181,ko:K01185,ko:K02027,ko:K07273,ko:K07451,ko:K17315,ko:K17318	ko02010,map02010	M00207,M00603,M00605	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02048	3.A.1.1,3.A.1.1.24,3.A.1.1.29,3.A.1.1.30,3.A.1.1.9	-	-	Glyco_hydro_25,LysM,Phage-tail_3
KFPFDFKC_03167	500632.CLONEX_00872	0.0	1045.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,2481D@186801|Clostridia	186801|Clostridia	U	Relaxase mobilization nuclease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
KFPFDFKC_03168	511680.BUTYVIB_02389	1.72e-129	367.0	COG0655@1|root,COG0655@2|Bacteria,1UHW0@1239|Firmicutes,24N5N@186801|Clostridia,4BZ31@830|Butyrivibrio	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
KFPFDFKC_03169	1280686.AUKE01000031_gene1554	7.05e-59	186.0	COG0454@1|root,COG0456@2|Bacteria,1VAQ8@1239|Firmicutes,24KVY@186801|Clostridia	186801|Clostridia	K	Acetyltransferase (GNAT) family	-	-	2.3.1.82	ko:K18816	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
KFPFDFKC_03170	511680.BUTYVIB_02388	2.59e-102	296.0	COG0454@1|root,COG0456@2|Bacteria,1VAJN@1239|Firmicutes,24H93@186801|Clostridia,4BZ8X@830|Butyrivibrio	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
KFPFDFKC_03171	511680.BUTYVIB_02387	2.6e-130	371.0	COG0406@1|root,COG0406@2|Bacteria,1V3RC@1239|Firmicutes,24GHZ@186801|Clostridia,4BYF3@830|Butyrivibrio	186801|Clostridia	G	Histidine phosphatase superfamily (branch 1)	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
KFPFDFKC_03172	190304.FN1445	0.0	1356.0	COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,37B56@32066|Fusobacteria	32066|Fusobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF2726
KFPFDFKC_03173	411463.EUBVEN_01883	2.11e-161	452.0	COG0494@1|root,COG3655@1|root,COG0494@2|Bacteria,COG3655@2|Bacteria,1UHU0@1239|Firmicutes,25F22@186801|Clostridia,25ZJK@186806|Eubacteriaceae	186801|Clostridia	L	COG COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
KFPFDFKC_03174	596323.HMPREF0554_0059	4.45e-18	87.0	COG3593@1|root,COG3593@2|Bacteria	2|Bacteria	L	DNA synthesis involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15
KFPFDFKC_03175	585394.RHOM_15945	3.75e-56	185.0	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03176	411462.DORLON_02271	1.52e-07	54.7	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia,27W4K@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03177	1235799.C818_00234	4.09e-26	100.0	COG1476@1|root,COG1476@2|Bacteria,1UVDI@1239|Firmicutes,25KG6@186801|Clostridia,27PDV@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
KFPFDFKC_03178	180332.JTGN01000009_gene4213	7.52e-70	270.0	COG3087@1|root,COG5492@1|root,COG3087@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	3.4.21.110	ko:K02519,ko:K08652	-	-	-	-	ko00000,ko01000,ko01002,ko03012,ko03029,ko03110	-	-	-	Gram_pos_anchor,NYN,PA,Peptidase_S8,SPOR,fn3_5
KFPFDFKC_03179	585394.RHOM_15945	1.08e-47	161.0	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03180	585394.RHOM_15945	6.19e-51	172.0	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03181	585394.RHOM_09375	1.64e-51	168.0	2AKH0@1|root,31B8X@2|Bacteria,1V6ZY@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF2975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
KFPFDFKC_03182	1235790.C805_03566	9.31e-34	117.0	COG3655@1|root,COG3655@2|Bacteria,1VESP@1239|Firmicutes,24QSQ@186801|Clostridia,25XC8@186806|Eubacteriaceae	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
KFPFDFKC_03183	585394.RHOM_09365	1.12e-125	384.0	COG0810@1|root,COG0810@2|Bacteria,1UJMR@1239|Firmicutes,251BT@186801|Clostridia	186801|Clostridia	M	Domain of unknown function (DUF4173)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4173
KFPFDFKC_03184	483218.BACPEC_02956	5.45e-22	95.9	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248IH@186801|Clostridia,268EB@186813|unclassified Clostridiales	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
KFPFDFKC_03185	585394.RHOM_10170	6.75e-165	470.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248IH@186801|Clostridia	186801|Clostridia	S	ABC-type transport system, periplasmic component surface lipoprotein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
KFPFDFKC_03186	483218.BACPEC_02957	1.59e-143	433.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,26BFA@186813|unclassified Clostridiales	186801|Clostridia	NT	Single cache domain 3	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,sCache_3_3
KFPFDFKC_03187	622312.ROSEINA2194_01368	7.71e-79	238.0	COG1051@1|root,COG1051@2|Bacteria,1UUZ0@1239|Firmicutes,24NDR@186801|Clostridia	186801|Clostridia	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
KFPFDFKC_03188	585394.RHOM_09310	3.39e-98	286.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia	186801|Clostridia	G	methylglyoxal synthase	mgsA	-	2.7.1.24,4.2.3.3	ko:K00859,ko:K01734	ko00640,ko00770,ko01100,ko01120,map00640,map00770,map01100,map01120	M00120	R00130,R01016	RC00002,RC00078,RC00424	ko00000,ko00001,ko00002,ko01000	-	-	-	MGS
KFPFDFKC_03189	585394.RHOM_09305	3.52e-178	499.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,248N9@186801|Clostridia	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
KFPFDFKC_03190	585394.RHOM_09300	1.82e-245	683.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
KFPFDFKC_03191	585394.RHOM_09295	2.08e-149	427.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia	186801|Clostridia	K	lysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
KFPFDFKC_03192	1256908.HMPREF0373_01084	5.64e-297	811.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,25V6G@186806|Eubacteriaceae	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
KFPFDFKC_03193	585394.RHOM_09285	9.36e-76	233.0	COG1011@1|root,COG1011@2|Bacteria,1V6I4@1239|Firmicutes,24JK7@186801|Clostridia	186801|Clostridia	S	HAD hydrolase, family IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
KFPFDFKC_03194	585394.RHOM_09280	1.73e-144	416.0	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,25AZ1@186801|Clostridia	186801|Clostridia	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
KFPFDFKC_03195	585394.RHOM_09275	0.0	904.0	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria,1TT1J@1239|Firmicutes,24BC2@186801|Clostridia	186801|Clostridia	N	-transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3,ABC_transp_aux
KFPFDFKC_03198	1256908.HMPREF0373_01181	2.76e-244	680.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,25VD8@186806|Eubacteriaceae	186801|Clostridia	C	citrate synthase	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
KFPFDFKC_03199	622312.ROSEINA2194_00357	1.81e-29	106.0	2DR14@1|root,339R7@2|Bacteria,1VMNT@1239|Firmicutes,24UVM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03200	585394.RHOM_09245	1.72e-112	323.0	COG3012@1|root,COG3012@2|Bacteria,1V1CC@1239|Firmicutes,24FYC@186801|Clostridia	186801|Clostridia	U	Psort location Cytoplasmic, score	secA_2	-	-	-	-	-	-	-	-	-	-	-	SEC-C
KFPFDFKC_03202	585394.RHOM_09240	2.92e-45	148.0	2DP3R@1|root,330E2@2|Bacteria,1VEPT@1239|Firmicutes,24QJB@186801|Clostridia	186801|Clostridia	S	COG NOG16856 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF1540
KFPFDFKC_03203	585394.RHOM_09230	5.85e-87	261.0	2C6U1@1|root,30XIE@2|Bacteria,1V4EP@1239|Firmicutes,24J3E@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
KFPFDFKC_03206	585394.RHOM_09220	1.49e-93	273.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia	186801|Clostridia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
KFPFDFKC_03207	622312.ROSEINA2194_01247	5.53e-197	549.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
KFPFDFKC_03208	622312.ROSEINA2194_01246	4.57e-60	191.0	2E3U8@1|root,32YRK@2|Bacteria,1VEYB@1239|Firmicutes,24QRX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
KFPFDFKC_03209	585394.RHOM_09205	0.0	1048.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia	186801|Clostridia	M	penicillin-binding protein	-	-	-	ko:K08384	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PBP_dimer,Transpeptidase
KFPFDFKC_03210	585394.RHOM_09200	0.0	935.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia	186801|Clostridia	M	penicillin-binding protein	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
KFPFDFKC_03211	585394.RHOM_09195	1.71e-198	553.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia	186801|Clostridia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
KFPFDFKC_03212	585394.RHOM_09190	3.3e-192	548.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
KFPFDFKC_03213	585394.RHOM_09185	4.55e-203	569.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
KFPFDFKC_03214	585394.RHOM_09180	7.63e-120	348.0	COG1589@1|root,COG1589@2|Bacteria,1V34X@1239|Firmicutes,248RF@186801|Clostridia	186801|Clostridia	M	COG1589 Cell division septal protein	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
KFPFDFKC_03215	585394.RHOM_09175	1.55e-231	643.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
KFPFDFKC_03216	742741.HMPREF9475_01248	6.81e-12	70.1	29ECG@1|root,301AF@2|Bacteria,1UY4W@1239|Firmicutes,24HI3@186801|Clostridia,21YX0@1506553|Lachnoclostridium	186801|Clostridia	M	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR	spoIIGA	-	-	ko:K06383	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_U4
KFPFDFKC_03217	622312.ROSEINA2194_01236	6.18e-130	374.0	COG1191@1|root,COG1191@2|Bacteria,1TP3T@1239|Firmicutes,24A4T@186801|Clostridia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigE	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
KFPFDFKC_03218	622312.ROSEINA2194_01235	0.0	907.0	COG1236@1|root,COG1236@2|Bacteria,1TQBH@1239|Firmicutes,248QR@186801|Clostridia	186801|Clostridia	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
KFPFDFKC_03219	585394.RHOM_09155	3.96e-159	449.0	COG1191@1|root,COG1191@2|Bacteria,1TPDD@1239|Firmicutes,24A1H@186801|Clostridia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigG	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
KFPFDFKC_03221	585394.RHOM_09140	4.71e-155	440.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24B81@186801|Clostridia	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF_2	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
KFPFDFKC_03223	585394.RHOM_08785	8.26e-308	863.0	COG0451@1|root,COG0451@2|Bacteria,1UYUX@1239|Firmicutes,24CYP@186801|Clostridia	186801|Clostridia	GM	Psort location CytoplasmicMembrane, score	-	-	5.1.3.2	ko:K01784,ko:K21009	ko00052,ko00520,ko01100,ko02025,map00052,map00520,map01100,map02025	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,RmlD_sub_bind
KFPFDFKC_03224	585394.RHOM_08780	1.37e-123	362.0	28H6W@1|root,2ZA4C@2|Bacteria,1UXGN@1239|Firmicutes,24AZN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03225	411469.EUBHAL_02519	6.71e-187	560.0	28N1Z@1|root,2ZB7X@2|Bacteria,1UZID@1239|Firmicutes,24F7M@186801|Clostridia,25Y86@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03226	585394.RHOM_08775	1.08e-184	542.0	28HJQ@1|root,2Z7UU@2|Bacteria,1UPMJ@1239|Firmicutes,24BW1@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2194
KFPFDFKC_03227	585394.RHOM_08770	3.31e-244	682.0	COG0438@1|root,COG0438@2|Bacteria,1TQ8U@1239|Firmicutes,24BAM@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	ko:K21011	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	DUF3492,Glycos_transf_1
KFPFDFKC_03228	585394.RHOM_08765	7.67e-251	699.0	COG4267@1|root,COG4267@2|Bacteria,1TRZE@1239|Firmicutes,24EQ7@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K21012	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	PelG
KFPFDFKC_03229	1235802.C823_04311	9.44e-11	62.4	2EA00@1|root,3345F@2|Bacteria,1VJQ9@1239|Firmicutes,24R0V@186801|Clostridia,25Z91@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2304
KFPFDFKC_03230	585394.RHOM_08755	3.51e-166	479.0	COG0438@1|root,COG0438@2|Bacteria,1V09V@1239|Firmicutes,24C11@186801|Clostridia	186801|Clostridia	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
KFPFDFKC_03231	585394.RHOM_08750	3.27e-142	406.0	COG1216@1|root,COG1216@2|Bacteria,1UAQP@1239|Firmicutes,25B5D@186801|Clostridia	186801|Clostridia	S	group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
KFPFDFKC_03232	585394.RHOM_08745	3.79e-92	291.0	28NI3@1|root,2ZBJM@2|Bacteria,1V27V@1239|Firmicutes,24FTG@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4874)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,DUF4874
KFPFDFKC_03233	411479.BACUNI_00969	1.06e-49	176.0	COG0463@1|root,COG0463@2|Bacteria,4NQ67@976|Bacteroidetes,2G06Z@200643|Bacteroidia,4AV2G@815|Bacteroidaceae	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
KFPFDFKC_03234	585394.RHOM_08735	1.87e-250	701.0	COG2244@1|root,COG2244@2|Bacteria,1TR1W@1239|Firmicutes,24917@186801|Clostridia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3
KFPFDFKC_03235	585394.RHOM_08730	5.42e-140	412.0	COG2244@1|root,COG2244@2|Bacteria,1V0I3@1239|Firmicutes,24F2V@186801|Clostridia	186801|Clostridia	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
KFPFDFKC_03236	585394.RHOM_08720	1.98e-165	481.0	2DBEW@1|root,2Z8UY@2|Bacteria,1UYFJ@1239|Firmicutes,2489J@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4874)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,DUF4874
KFPFDFKC_03237	1235792.C808_02507	1.46e-167	477.0	COG1216@1|root,COG1216@2|Bacteria,1VV6P@1239|Firmicutes,25EH9@186801|Clostridia,27JXT@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
KFPFDFKC_03238	97139.C824_04122	2.93e-77	236.0	2B66C@1|root,31Z3H@2|Bacteria,1V6U0@1239|Firmicutes,24ICU@186801|Clostridia,36J7Y@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03239	1235799.C818_02800	2.26e-96	296.0	COG0392@1|root,COG0392@2|Bacteria,1TXG8@1239|Firmicutes,24A1A@186801|Clostridia,27K01@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
KFPFDFKC_03240	585394.RHOM_08705	1.16e-52	169.0	2BZS0@1|root,343DQ@2|Bacteria,1VZ4U@1239|Firmicutes,25450@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03241	585394.RHOM_08710	1.6e-55	175.0	28V59@1|root,2ZH8H@2|Bacteria,1W3K5@1239|Firmicutes,255DA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03242	585394.RHOM_08700	0.0	932.0	COG1132@1|root,COG1132@2|Bacteria,1TRJF@1239|Firmicutes,249CN@186801|Clostridia	186801|Clostridia	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
KFPFDFKC_03243	411469.EUBHAL_02535	1.15e-86	275.0	2DBZW@1|root,2ZC46@2|Bacteria,1V2V4@1239|Firmicutes,24H1D@186801|Clostridia	186801|Clostridia	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
KFPFDFKC_03244	1235802.C823_04319	6.48e-50	163.0	COG0681@1|root,COG0681@2|Bacteria,1VFKY@1239|Firmicutes,24RQG@186801|Clostridia,25XJH@186806|Eubacteriaceae	186801|Clostridia	U	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
KFPFDFKC_03245	1235802.C823_05151	2.67e-72	221.0	COG4708@1|root,COG4708@2|Bacteria,1V9YK@1239|Firmicutes,24N9H@186801|Clostridia,25WR7@186806|Eubacteriaceae	186801|Clostridia	S	QueT transporter	queT	-	-	-	-	-	-	-	-	-	-	-	QueT
KFPFDFKC_03246	877421.AUJT01000002_gene1161	9.69e-123	354.0	COG3010@1|root,COG3010@2|Bacteria,1TSR7@1239|Firmicutes,24AVB@186801|Clostridia,27JDF@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)	nanE	-	5.1.3.9	ko:K01788	ko00520,map00520	-	R02087	RC00290	ko00000,ko00001,ko01000	-	-	-	NanE
KFPFDFKC_03247	1111135.HMPREF1248_0984	4.66e-211	594.0	COG2610@1|root,COG2610@2|Bacteria,2I7H9@201174|Actinobacteria	201174|Actinobacteria	EG	gluconate transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03248	1121296.JONJ01000003_gene756	0.0	1028.0	COG0145@1|root,COG0145@2|Bacteria,1TQVB@1239|Firmicutes,24AJ7@186801|Clostridia,21YSM@1506553|Lachnoclostridium	186801|Clostridia	EQ	Hydantoinase/oxoprolinase N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
KFPFDFKC_03249	997346.HMPREF9374_0063	2.49e-18	89.4	2AG0K@1|root,3164N@2|Bacteria,1V7CN@1239|Firmicutes,4HSP9@91061|Bacilli,27C2K@186824|Thermoactinomycetaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03250	1121296.JONJ01000003_gene758	3.86e-221	621.0	COG0644@1|root,COG0644@2|Bacteria,1TR0D@1239|Firmicutes,24BE3@186801|Clostridia,21ZUQ@1506553|Lachnoclostridium	186801|Clostridia	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
KFPFDFKC_03251	877421.AUJT01000002_gene1169	2.03e-107	320.0	COG1737@1|root,COG1737@2|Bacteria,1TR5E@1239|Firmicutes,247Z7@186801|Clostridia,27K6U@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
KFPFDFKC_03252	592026.GCWU0000282_000636	5.19e-124	365.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia	186801|Clostridia	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
KFPFDFKC_03253	585394.RHOM_09110	0.0	1041.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia	186801|Clostridia	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
KFPFDFKC_03254	411489.CLOL250_01411	5.71e-62	200.0	2EX79@1|root,33QI5@2|Bacteria,1VS8K@1239|Firmicutes,24YCQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03255	742765.HMPREF9457_01596	0.0	890.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,248DZ@186801|Clostridia,27WC8@189330|Dorea	186801|Clostridia	T	5TM C-terminal transporter carbon starvation CstA	cstA	-	-	-	-	-	-	-	-	-	-	-	CstA,CstA_5TM
KFPFDFKC_03256	483218.BACPEC_01486	1.83e-184	519.0	28JHK@1|root,2Z9B4@2|Bacteria,1TS7Y@1239|Firmicutes,249S0@186801|Clostridia,26AQK@186813|unclassified Clostridiales	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03257	585394.RHOM_09105	3.73e-125	367.0	COG3854@1|root,COG3854@2|Bacteria,1TQ23@1239|Firmicutes,248S2@186801|Clostridia	186801|Clostridia	S	stage III sporulation protein AA	spoIIIAA	-	-	ko:K06390	-	-	-	-	ko00000	-	-	-	T2SSE
KFPFDFKC_03258	397290.C810_02092	4.31e-09	60.5	29N29@1|root,30900@2|Bacteria,1U486@1239|Firmicutes,24GD0@186801|Clostridia,27PVV@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Stage III sporulation protein AB (spore_III_AB)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_III_AB
KFPFDFKC_03259	585394.RHOM_09095	1.58e-33	115.0	2E555@1|root,32ZY3@2|Bacteria,1VEM4@1239|Firmicutes,24QNR@186801|Clostridia	186801|Clostridia	S	Stage III sporulation protein AC	spoIIIAC	-	-	ko:K06392	-	-	-	-	ko00000	-	-	-	SpoIIIAC
KFPFDFKC_03260	585394.RHOM_09090	2.03e-44	148.0	2CPUI@1|root,32SJW@2|Bacteria,1VA9Y@1239|Firmicutes,24NK6@186801|Clostridia	186801|Clostridia	S	Stage III sporulation protein AD	spoIIIAD	-	-	ko:K06393	-	-	-	-	ko00000	-	-	-	SpoIIIAC
KFPFDFKC_03261	622312.ROSEINA2194_01224	3.92e-123	367.0	2C2CG@1|root,2Z7PW@2|Bacteria,1TQQ2@1239|Firmicutes,24AH2@186801|Clostridia	186801|Clostridia	S	stage III sporulation protein AE	spoIIIAE	-	-	ko:K06394	-	-	-	-	ko00000	-	-	-	Spore_III_AE
KFPFDFKC_03263	622312.ROSEINA2194_01222	3.35e-52	173.0	2E6BB@1|root,330Z5@2|Bacteria,1VF3M@1239|Firmicutes,24RAX@186801|Clostridia	186801|Clostridia	S	Stage III sporulation protein AG	spoIIIAG	-	-	ko:K06396	-	-	-	-	ko00000	-	-	-	-
KFPFDFKC_03264	622312.ROSEINA2194_01221	2.62e-93	283.0	28ZIG@1|root,2ZM9W@2|Bacteria,1V2JN@1239|Firmicutes,25BHX@186801|Clostridia	186801|Clostridia	S	SpoIIIAH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIIAH
KFPFDFKC_03265	585394.RHOM_08965	4.82e-258	709.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
KFPFDFKC_03266	585394.RHOM_08960	0.0	1030.0	COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,247X3@186801|Clostridia	186801|Clostridia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
KFPFDFKC_03267	585394.RHOM_08955	6.1e-53	169.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
KFPFDFKC_03269	622312.ROSEINA2194_01218	2.53e-217	605.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
KFPFDFKC_03270	622312.ROSEINA2194_01217	3.11e-76	234.0	COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,24J7X@186801|Clostridia	186801|Clostridia	S	Regulatory protein RecX	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
KFPFDFKC_03271	622312.ROSEINA2194_01216	4.61e-289	799.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia	186801|Clostridia	M	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
KFPFDFKC_03273	585394.RHOM_13875	5.06e-125	362.0	COG0745@1|root,COG0745@2|Bacteria,1UDAQ@1239|Firmicutes,249RQ@186801|Clostridia	186801|Clostridia	KT	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	kdpE_1	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
KFPFDFKC_03275	585394.RHOM_08930	2.76e-110	319.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia	186801|Clostridia	L	Hydrolase, nudix family	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05505	NUDIX
KFPFDFKC_03277	585394.RHOM_08920	6.22e-148	423.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
KFPFDFKC_03278	585394.RHOM_08915	4.64e-232	640.0	COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes,24842@186801|Clostridia	186801|Clostridia	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroH	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS07240	DAHP_synth_1
KFPFDFKC_03279	622312.ROSEINA2194_02777	3.85e-101	301.0	COG0710@1|root,COG0710@2|Bacteria,1TSPN@1239|Firmicutes,249EX@186801|Clostridia	186801|Clostridia	E	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,SKI
KFPFDFKC_03280	622312.ROSEINA2194_02776	8.95e-34	123.0	COG1846@1|root,COG1846@2|Bacteria,1VGEP@1239|Firmicutes,24QRJ@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR
KFPFDFKC_03281	585394.RHOM_08900	0.0	1132.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia	186801|Clostridia	V	Abc transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
KFPFDFKC_03282	622312.ROSEINA2194_02774	0.0	1031.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
KFPFDFKC_03283	622312.ROSEINA2194_02772	4.64e-193	540.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia	186801|Clostridia	C	Belongs to the LDH MDH superfamily. LDH family	-	-	-	-	-	-	-	-	-	-	-	-	Ldh_1_C,Ldh_1_N
KFPFDFKC_03284	585394.RHOM_08885	8.55e-163	468.0	COG1442@1|root,COG1442@2|Bacteria,1U86V@1239|Firmicutes,24CPG@186801|Clostridia	186801|Clostridia	M	Domain of unknown function (DUF4422)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4422
KFPFDFKC_03286	585394.RHOM_08880	3.52e-136	405.0	COG3103@1|root,COG3103@2|Bacteria,COG4991@2|Bacteria,1USNV@1239|Firmicutes,24DRI@186801|Clostridia	186801|Clostridia	T	Bacterial SH3 domain homologues	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
KFPFDFKC_03287	622312.ROSEINA2194_02768	1.98e-141	404.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluF	-	5.4.99.21,5.4.99.22	ko:K06178,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
KFPFDFKC_03288	585394.RHOM_08870	0.0	1097.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
KFPFDFKC_03289	622312.ROSEINA2194_02766	1.14e-204	568.0	COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,247NP@186801|Clostridia	186801|Clostridia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS11970	HTS
KFPFDFKC_03292	318464.IO99_03650	8.8e-44	149.0	COG3177@1|root,COG3177@2|Bacteria,1TZWX@1239|Firmicutes,247MZ@186801|Clostridia,36FX9@31979|Clostridiaceae	186801|Clostridia	K	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
KFPFDFKC_03293	585394.RHOM_08855	2.52e-76	228.0	COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,24JNM@186801|Clostridia	186801|Clostridia	S	protein conserved in bacteria	asp	-	-	-	-	-	-	-	-	-	-	-	Asp23
KFPFDFKC_03294	622312.ROSEINA2194_02748	2.31e-44	147.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
KFPFDFKC_03295	622312.ROSEINA2194_02747	5.74e-202	569.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,247KE@186801|Clostridia	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
KFPFDFKC_03296	622312.ROSEINA2194_02746	1.32e-20	84.0	COG1722@1|root,COG1722@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease VII activity	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
KFPFDFKC_03297	585394.RHOM_08835	9.06e-163	461.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,248DE@186801|Clostridia	186801|Clostridia	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iHN637.CLJU_RS05465	polyprenyl_synt
KFPFDFKC_03298	585394.RHOM_08830	0.0	1061.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
KFPFDFKC_03299	622312.ROSEINA2194_02743	1.84e-155	440.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,247VH@186801|Clostridia	186801|Clostridia	J	Ribosomal RNA large subunit methyltransferase J	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
KFPFDFKC_03300	622312.ROSEINA2194_02742	4.85e-138	398.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia	186801|Clostridia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
KFPFDFKC_03301	622312.ROSEINA2194_02741	1.05e-80	241.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
KFPFDFKC_03302	585394.RHOM_08810	8.41e-232	657.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,247KB@186801|Clostridia	186801|Clostridia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
KFPFDFKC_03303	585394.RHOM_08805	5.79e-162	468.0	COG3480@1|root,COG3480@2|Bacteria,1UI0S@1239|Firmicutes,25E9E@186801|Clostridia	186801|Clostridia	T	Stage IV sporulation protein B	spoIVB	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S55
KFPFDFKC_03304	585394.RHOM_08800	2.12e-153	453.0	COG0457@1|root,COG2199@1|root,COG0457@2|Bacteria,COG3706@2|Bacteria,1TS77@1239|Firmicutes,24E4N@186801|Clostridia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,TPR_8
KFPFDFKC_03305	585394.RHOM_08795	3.17e-154	437.0	COG2201@1|root,COG2201@2|Bacteria,1VQS3@1239|Firmicutes,25E3X@186801|Clostridia	186801|Clostridia	NT	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process	spo0A	-	-	ko:K03413,ko:K07699	ko02020,ko02024,ko02030,map02020,map02024,map02030	M00485,M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg,Spo0A_C
KFPFDFKC_03306	622312.ROSEINA2194_02735	2.08e-285	788.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	-	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
KFPFDFKC_03307	585394.RHOM_08680	7.96e-110	328.0	28PM6@1|root,2ZCAA@2|Bacteria,1V4NT@1239|Firmicutes,24HIP@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03308	622312.ROSEINA2194_02732	4.23e-183	517.0	COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia	186801|Clostridia	P	ABC transporter, solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
KFPFDFKC_03309	622312.ROSEINA2194_02731	1.36e-136	392.0	COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,25E3C@186801|Clostridia	186801|Clostridia	P	Abc transporter, permease protein	potC	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
KFPFDFKC_03310	622312.ROSEINA2194_02730	8.71e-159	449.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,247Y8@186801|Clostridia	186801|Clostridia	P	ABC transporter, permease protein	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
KFPFDFKC_03311	622312.ROSEINA2194_02729	1.37e-231	640.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
KFPFDFKC_03312	622312.ROSEINA2194_02728	8.32e-94	279.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1V1K5@1239|Firmicutes,24FTC@186801|Clostridia	186801|Clostridia	K	domain protein	puuR	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3
KFPFDFKC_03314	585394.RHOM_08625	2.55e-123	354.0	COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,24850@186801|Clostridia	186801|Clostridia	F	Cytidine monophosphokinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
KFPFDFKC_03315	585394.RHOM_08620	8.05e-202	568.0	COG2755@1|root,COG2755@2|Bacteria,1UYZ1@1239|Firmicutes,24BMN@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1,Lipase_GDSL_2
KFPFDFKC_03316	1121115.AXVN01000012_gene3091	7.27e-15	68.9	COG2104@1|root,COG2104@2|Bacteria,1VKB4@1239|Firmicutes,25HV0@186801|Clostridia,3Y0TI@572511|Blautia	186801|Clostridia	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
KFPFDFKC_03317	537007.BLAHAN_06473	2.57e-149	424.0	COG2022@1|root,COG2022@2|Bacteria,1TQZ1@1239|Firmicutes,247TJ@186801|Clostridia,3XZG0@572511|Blautia	186801|Clostridia	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
KFPFDFKC_03318	1280698.AUJS01000004_gene2938	3.24e-238	661.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia,27URQ@189330|Dorea	186801|Clostridia	C	Biotin and Thiamin Synthesis associated domain	thiH	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
KFPFDFKC_03319	411459.RUMOBE_00194	1.68e-68	215.0	COG0352@1|root,COG0352@2|Bacteria,1V4SE@1239|Firmicutes,24JTR@186801|Clostridia,3Y00P@572511|Blautia	186801|Clostridia	H	Thiamine monophosphate synthase	tenI	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06600	TMP-TENI
KFPFDFKC_03320	622312.ROSEINA2194_02259	1.67e-80	249.0	COG0850@1|root,COG0850@2|Bacteria,1VAPC@1239|Firmicutes,24MV1@186801|Clostridia	186801|Clostridia	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C
KFPFDFKC_03321	622312.ROSEINA2194_02260	2.91e-158	447.0	COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,249BB@186801|Clostridia	186801|Clostridia	D	Belongs to the ParA family	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
KFPFDFKC_03322	658086.HMPREF0994_01119	3.93e-46	149.0	COG0851@1|root,COG0851@2|Bacteria,1VFST@1239|Firmicutes,24QT6@186801|Clostridia,27NQT@186928|unclassified Lachnospiraceae	186801|Clostridia	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
KFPFDFKC_03323	411463.EUBVEN_02080	9.83e-197	555.0	COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,248AY@186801|Clostridia,25UZ8@186806|Eubacteriaceae	186801|Clostridia	E	Aminotransferase, class I	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
KFPFDFKC_03324	411463.EUBVEN_02011	3.87e-160	451.0	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,24849@186801|Clostridia,25V2W@186806|Eubacteriaceae	186801|Clostridia	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
KFPFDFKC_03326	622312.ROSEINA2194_02797	9.73e-122	377.0	COG2871@1|root,COG3894@1|root,COG2871@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia	186801|Clostridia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
KFPFDFKC_03327	1226325.HMPREF1548_00183	1.33e-257	717.0	COG4209@1|root,COG4209@2|Bacteria,1TSTC@1239|Firmicutes,24AFM@186801|Clostridia,36FY9@31979|Clostridiaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
KFPFDFKC_03328	1226325.HMPREF1548_00184	3.1e-203	565.0	COG0395@1|root,COG0395@2|Bacteria,1TRB1@1239|Firmicutes,2488P@186801|Clostridia,36F12@31979|Clostridiaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
KFPFDFKC_03329	658086.HMPREF0994_06596	0.0	949.0	COG1653@1|root,COG1653@2|Bacteria,1TPHG@1239|Firmicutes,24AFQ@186801|Clostridia,27J6A@186928|unclassified Lachnospiraceae	186801|Clostridia	G	ABC transporter substrate-binding protein	-	-	-	ko:K02027,ko:K17318	ko02010,map02010	M00207,M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.29,3.A.1.1.9	-	-	-
KFPFDFKC_03330	1469948.JPNB01000002_gene2805	3.91e-66	208.0	COG5578@1|root,COG5578@2|Bacteria,1VJNV@1239|Firmicutes,24SDJ@186801|Clostridia	186801|Clostridia	S	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
KFPFDFKC_03331	1469948.JPNB01000002_gene2802	0.0	1005.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,36FQ1@31979|Clostridiaceae	186801|Clostridia	G	beta-galactosidase	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
KFPFDFKC_03332	1410622.JNKY01000019_gene1711	2.7e-244	684.0	COG3669@1|root,COG3669@2|Bacteria,1TT4V@1239|Firmicutes,24A0S@186801|Clostridia,27IVN@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
KFPFDFKC_03333	573061.Clocel_0036	8.6e-122	379.0	COG2972@1|root,COG2972@2|Bacteria,1UY73@1239|Firmicutes,24AX8@186801|Clostridia,36G3Y@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase,dCache_1
KFPFDFKC_03334	1280685.AUKC01000023_gene851	1.4e-183	535.0	COG1653@1|root,COG1653@2|Bacteria,1TQ1D@1239|Firmicutes,24AFW@186801|Clostridia,4BXI8@830|Butyrivibrio	186801|Clostridia	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
KFPFDFKC_03335	1280390.CBQR020000094_gene2073	2.15e-257	719.0	COG1492@1|root,COG1492@2|Bacteria,1TP5E@1239|Firmicutes,4HAQW@91061|Bacilli,26UJH@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,CbiA,GATase_3
KFPFDFKC_03336	877420.ATVW01000017_gene1701	2.65e-139	408.0	COG2038@1|root,COG2038@2|Bacteria,1TPC1@1239|Firmicutes,25DH5@186801|Clostridia,27IYG@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
KFPFDFKC_03337	1235793.C809_02443	4.09e-50	167.0	COG2087@1|root,COG2087@2|Bacteria,1V6F8@1239|Firmicutes,24JF6@186801|Clostridia,27M8T@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Cobinamide kinase / cobinamide phosphate guanyltransferase	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
KFPFDFKC_03338	1120746.CCNL01000008_gene545	5.21e-105	311.0	COG0368@1|root,COG0368@2|Bacteria	2|Bacteria	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008818,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
KFPFDFKC_03339	537007.BLAHAN_05799	8.85e-29	108.0	COG2087@1|root,COG2087@2|Bacteria,1VG8S@1239|Firmicutes,24QSM@186801|Clostridia,3Y0HX@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	CobU
KFPFDFKC_03340	1120746.CCNL01000008_gene547	1.41e-69	218.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	cobC	-	3.1.3.73,6.3.1.10	ko:K02226,ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R04594,R06529,R07302,R11173	RC00017,RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
KFPFDFKC_03341	622312.ROSEINA2194_01858	2.27e-140	407.0	COG1270@1|root,COG1270@2|Bacteria,1TQ3X@1239|Firmicutes,247PR@186801|Clostridia	186801|Clostridia	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
KFPFDFKC_03342	689781.AUJX01000003_gene2930	3.8e-80	241.0	COG3467@1|root,COG3467@2|Bacteria,1V6NS@1239|Firmicutes,24JA3@186801|Clostridia,2PSHU@265975|Oribacterium	186801|Clostridia	S	Pyridoxamine 5'-phosphate oxidase	nimA	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
KFPFDFKC_03343	622312.ROSEINA2194_02722	1.77e-30	113.0	2EKR7@1|root,33EEZ@2|Bacteria,1VQ0F@1239|Firmicutes,24UDN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03344	585394.RHOM_08610	4.43e-69	214.0	COG2206@1|root,COG2206@2|Bacteria,1UI74@1239|Firmicutes,25EC7@186801|Clostridia	186801|Clostridia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
KFPFDFKC_03345	585394.RHOM_08605	1.31e-158	458.0	COG4641@1|root,COG4641@2|Bacteria,1V642@1239|Firmicutes,24IV8@186801|Clostridia	186801|Clostridia	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
KFPFDFKC_03346	622312.ROSEINA2194_02720	7.62e-128	367.0	COG1636@1|root,COG1636@2|Bacteria,1TT7H@1239|Firmicutes,248EA@186801|Clostridia	186801|Clostridia	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
KFPFDFKC_03347	585394.RHOM_08595	2.25e-305	836.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,2489H@186801|Clostridia	186801|Clostridia	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
KFPFDFKC_03348	585394.RHOM_08590	2.31e-258	708.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,248ZR@186801|Clostridia	186801|Clostridia	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
KFPFDFKC_03349	585394.RHOM_08585	4.27e-233	652.0	COG1672@1|root,COG1672@2|Bacteria,1TR21@1239|Firmicutes,24ADD@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
KFPFDFKC_03350	585394.RHOM_08580	0.0	2013.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	traI	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
KFPFDFKC_03351	622312.ROSEINA2194_01352	2.5e-146	414.0	COG1207@1|root,COG1207@2|Bacteria	2|Bacteria	M	glucosamine-1-phosphate N-acetyltransferase activity	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
KFPFDFKC_03352	622312.ROSEINA2194_01774	1.73e-151	448.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,25BET@186801|Clostridia	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
KFPFDFKC_03353	585394.RHOM_08565	7.75e-114	352.0	COG1033@1|root,COG1033@2|Bacteria,1VIN4@1239|Firmicutes	1239|Firmicutes	S	YARHG	-	-	-	-	-	-	-	-	-	-	-	-	YARHG
KFPFDFKC_03354	585394.RHOM_08560	1.39e-165	462.0	COG0822@1|root,COG0822@2|Bacteria,1TQEQ@1239|Firmicutes,248ID@186801|Clostridia	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	NifU_N
KFPFDFKC_03355	622312.ROSEINA2194_01354	3.33e-242	665.0	2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	GGGtGRT
KFPFDFKC_03356	622312.ROSEINA2194_04170	9.53e-275	763.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,248FH@186801|Clostridia	186801|Clostridia	L	ImpB MucB SamB family protein	-	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
KFPFDFKC_03357	1226322.HMPREF1545_00232	1.46e-43	147.0	2DMPJ@1|root,32SWG@2|Bacteria,1V7RA@1239|Firmicutes,24NGU@186801|Clostridia,2N7F0@216572|Oscillospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03358	585394.RHOM_08090	3e-272	776.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,2493H@186801|Clostridia	186801|Clostridia	S	YhgE Pip	pip1	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	ABC2_membrane,ABC2_membrane_3,DUF3533
KFPFDFKC_03359	585394.RHOM_08085	1.44e-46	156.0	COG1511@1|root,COG1511@2|Bacteria,1VFYY@1239|Firmicutes,24RU2@186801|Clostridia	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03360	585394.RHOM_08080	3.23e-288	813.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,2493H@186801|Clostridia	186801|Clostridia	S	YhgE Pip	pip1	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	ABC2_membrane,ABC2_membrane_3,DUF3533
KFPFDFKC_03362	585394.RHOM_08065	2.56e-104	303.0	COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,24HZM@186801|Clostridia	186801|Clostridia	E	Acetolactate synthase, small subunit	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10025	ACT,ACT_5,ALS_ss_C
KFPFDFKC_03363	622312.ROSEINA2194_01363	1.42e-245	674.0	COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia	186801|Clostridia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
KFPFDFKC_03364	585394.RHOM_08055	0.0	1599.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
KFPFDFKC_03365	585394.RHOM_08050	7.88e-268	739.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
KFPFDFKC_03366	585394.RHOM_08035	4.15e-184	515.0	COG0583@1|root,COG0583@2|Bacteria,1TR84@1239|Firmicutes,24BU7@186801|Clostridia	186801|Clostridia	K	lysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
KFPFDFKC_03367	585394.RHOM_08030	1.1e-294	805.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01703,ko:K20452	ko00290,ko00660,ko00760,ko00966,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map00966,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04465	Aconitase
KFPFDFKC_03368	622312.ROSEINA2194_03857	1.67e-110	318.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01704,ko:K20453	ko00290,ko00660,ko00760,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R10170	RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
KFPFDFKC_03369	1469948.JPNB01000002_gene2888	8.4e-80	246.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1TQ2W@1239|Firmicutes,24A5W@186801|Clostridia,36VIU@31979|Clostridiaceae	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
KFPFDFKC_03370	411489.CLOL250_01712	6.74e-35	121.0	29A1J@1|root,34A7F@2|Bacteria,1W04K@1239|Firmicutes,253UG@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03371	1256908.HMPREF0373_02163	9.07e-30	108.0	2EPX6@1|root,328RW@2|Bacteria,1UUQ7@1239|Firmicutes,257FE@186801|Clostridia	1256908.HMPREF0373_02163|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03372	622312.ROSEINA2194_00554	3.71e-105	303.0	28PS7@1|root,2ZCDT@2|Bacteria,1V252@1239|Firmicutes,24GY8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03373	537007.BLAHAN_05371	4.91e-153	433.0	COG4200@1|root,COG4200@2|Bacteria,1TT70@1239|Firmicutes,24ANA@186801|Clostridia,3Y0J5@572511|Blautia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4
KFPFDFKC_03374	742765.HMPREF9457_03145	5.59e-176	491.0	COG1668@1|root,COG1668@2|Bacteria,1U5Z3@1239|Firmicutes,24AXX@186801|Clostridia,27WN5@189330|Dorea	186801|Clostridia	CP	ABC-2 family transporter protein	-	-	-	ko:K01992,ko:K19310	ko02010,map02010	M00254,M00747	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.131.1	-	-	ABC2_membrane_4
KFPFDFKC_03375	742765.HMPREF9457_03144	2.66e-218	602.0	COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,247M8@186801|Clostridia	186801|Clostridia	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K19309	ko02010,map02010	M00747	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.131.1	-	-	ABC_tran
KFPFDFKC_03376	457412.RSAG_02023	1.34e-205	570.0	COG0642@1|root,COG2205@2|Bacteria,1TXC7@1239|Firmicutes,2492E@186801|Clostridia,3WHRJ@541000|Ruminococcaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
KFPFDFKC_03377	1121115.AXVN01000102_gene3594	2.7e-163	457.0	COG0745@1|root,COG0745@2|Bacteria,1TSCM@1239|Firmicutes,248K7@186801|Clostridia	186801|Clostridia	K	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
KFPFDFKC_03378	1121115.AXVN01000151_gene3972	4.54e-41	134.0	COG2909@1|root,COG2909@2|Bacteria,1VGAF@1239|Firmicutes,24SMP@186801|Clostridia,3Y0SH@572511|Blautia	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
KFPFDFKC_03379	411461.DORFOR_03165	6.51e-89	263.0	COG1595@1|root,COG1595@2|Bacteria,1V1EX@1239|Firmicutes,24BBF@186801|Clostridia,27VRX@189330|Dorea	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
KFPFDFKC_03380	622312.ROSEINA2194_03345	7.43e-60	196.0	2C0GJ@1|root,2Z7PN@2|Bacteria,1V0HT@1239|Firmicutes,24FCI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03382	622312.ROSEINA2194_01181	2.32e-121	350.0	2DQ6A@1|root,334Y3@2|Bacteria,1VJ8J@1239|Firmicutes,24TVF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03383	622312.ROSEINA2194_01182	6.72e-242	665.0	28KQP@1|root,2ZA8F@2|Bacteria,1UY56@1239|Firmicutes,25DWY@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4885
KFPFDFKC_03384	585394.RHOM_12560	2.3e-124	354.0	28MQP@1|root,2ZAZH@2|Bacteria,1UBV0@1239|Firmicutes,24FBQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03385	585394.RHOM_16345	3.01e-145	410.0	2DB9G@1|root,2Z7WS@2|Bacteria,1TRCU@1239|Firmicutes,249J8@186801|Clostridia	186801|Clostridia	S	Domain of unknown function, E. rectale Gene description (DUF3879)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3879
KFPFDFKC_03386	622312.ROSEINA2194_03081	6.56e-128	371.0	COG3290@1|root,COG3290@2|Bacteria,1V225@1239|Firmicutes,24DB7@186801|Clostridia	186801|Clostridia	T	signal transduction protein with a C-terminal ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
KFPFDFKC_03387	180332.JTGN01000006_gene3187	9.7e-08	62.0	COG3468@1|root,COG3934@1|root,COG4409@1|root,COG4733@1|root,COG5492@1|root,COG3468@2|Bacteria,COG3934@2|Bacteria,COG4409@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria,1UI9U@1239|Firmicutes,24C9Z@186801|Clostridia	186801|Clostridia	G	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Big_3,DUF4091,Laminin_G_3,Lipase_GDSL_2
KFPFDFKC_03391	622312.ROSEINA2194_03741	6.11e-82	244.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
KFPFDFKC_03393	1235799.C818_03095	8.76e-121	350.0	COG0037@1|root,COG0037@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia,27IBK@186928|unclassified Lachnospiraceae	186801|Clostridia	D	PP-loop family	ttcA2	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3,Rhodanese
KFPFDFKC_03394	585394.RHOM_07590	1.65e-212	591.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,25C3N@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	xerS	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
KFPFDFKC_03395	585394.RHOM_07585	1.32e-149	423.0	COG0204@1|root,COG0204@2|Bacteria,1TTPK@1239|Firmicutes,24B6K@186801|Clostridia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
KFPFDFKC_03396	1121115.AXVN01000100_gene825	6.86e-115	344.0	COG4467@1|root,COG4467@2|Bacteria,1UYI4@1239|Firmicutes,2497B@186801|Clostridia	186801|Clostridia	S	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
KFPFDFKC_03397	500632.CLONEX_00591	1.54e-243	745.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,1TPQA@1239|Firmicutes,2491X@186801|Clostridia	186801|Clostridia	L	helicase C-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,N6_Mtase,ResIII,SNF2_N
KFPFDFKC_03398	861454.HMPREF9099_01778	5.63e-38	134.0	2AHN9@1|root,31806@2|Bacteria,1V94S@1239|Firmicutes,24MK7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03400	1235802.C823_01624	1.5e-116	344.0	28MNT@1|root,2ZAY9@2|Bacteria,1UJWE@1239|Firmicutes,248QQ@186801|Clostridia,25Y0Q@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03404	585394.RHOM_05235	5.87e-14	69.7	2EG0W@1|root,339SX@2|Bacteria,1VKDR@1239|Firmicutes,24S7Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03405	585394.RHOM_05230	2.1e-148	442.0	28I5Y@1|root,2Z892@2|Bacteria,1UYUF@1239|Firmicutes,24CM9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03406	585394.RHOM_05225	3.72e-58	190.0	COG0630@1|root,COG0630@2|Bacteria,1UHT2@1239|Firmicutes,25EN1@186801|Clostridia	186801|Clostridia	NU	COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
KFPFDFKC_03408	483218.BACPEC_02841	1.05e-125	358.0	COG1396@1|root,COG1396@2|Bacteria,1V9ZU@1239|Firmicutes,25PFH@186801|Clostridia,26CEE@186813|unclassified Clostridiales	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
KFPFDFKC_03410	585394.RHOM_16350	7.01e-125	365.0	COG3290@1|root,COG3290@2|Bacteria,1V225@1239|Firmicutes,24DB7@186801|Clostridia	186801|Clostridia	T	signal transduction protein with a C-terminal ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
KFPFDFKC_03411	585394.RHOM_16345	5.43e-148	417.0	2DB9G@1|root,2Z7WS@2|Bacteria,1TRCU@1239|Firmicutes,249J8@186801|Clostridia	186801|Clostridia	S	Domain of unknown function, E. rectale Gene description (DUF3879)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3879
KFPFDFKC_03412	622312.ROSEINA2194_02680	1.7e-28	106.0	2AY2J@1|root,31Q4C@2|Bacteria,1V70J@1239|Firmicutes,24JN7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03413	622312.ROSEINA2194_04246	0.0	930.0	28RNQ@1|root,2ZE1D@2|Bacteria,1V1HU@1239|Firmicutes,24GGJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03414	469382.Hbor_04090	1.53e-32	122.0	arCOG10869@1|root,arCOG10869@2157|Archaea	2157|Archaea	S	Domain of unknown function (DUF4157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,GH-E
KFPFDFKC_03415	1196324.A374_00120	1.26e-49	165.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_4,Ank_5
KFPFDFKC_03416	1297534.CAUJ01000008_gene811	3.08e-42	141.0	COG4859@1|root,COG4859@2|Bacteria,1VG52@1239|Firmicutes,4HSKZ@91061|Bacilli	91061|Bacilli	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2185
KFPFDFKC_03418	1345695.CLSA_c07870	1.57e-33	136.0	COG3209@1|root,COG3501@1|root,COG3209@2|Bacteria,COG3501@2|Bacteria,1TR8F@1239|Firmicutes,248C6@186801|Clostridia,36F1J@31979|Clostridiaceae	186801|Clostridia	M	YD repeat (two copies)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD,RHS_repeat
KFPFDFKC_03419	1449338.JQLU01000005_gene1359	2.82e-82	249.0	29NMT@1|root,309JR@2|Bacteria,1V4W9@1239|Firmicutes,4HI6R@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1629
KFPFDFKC_03422	1410632.JHWW01000013_gene228	8.24e-05	48.9	COG5492@1|root,COG5492@2|Bacteria,1V62C@1239|Firmicutes	1239|Firmicutes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Flg_new
KFPFDFKC_03423	1280696.ATVY01000024_gene1018	4.92e-259	723.0	COG0488@1|root,COG0488@2|Bacteria,1TU6J@1239|Firmicutes,24APJ@186801|Clostridia,4BX94@830|Butyrivibrio	186801|Clostridia	S	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
KFPFDFKC_03424	679937.Bcop_0088	1.9e-72	222.0	COG0617@1|root,COG0617@2|Bacteria,4NZY6@976|Bacteroidetes,2FQ7N@200643|Bacteroidia,4ARIS@815|Bacteroidaceae	976|Bacteroidetes	J	Aminoglycoside-2''-adenylyltransferase	-	-	-	ko:K19545	-	-	-	-	ko00000,ko01504	-	-	-	Aminoglyc_resit
KFPFDFKC_03426	397288.C806_04570	2.21e-05	53.5	COG1345@1|root,COG1345@2|Bacteria,1VU42@1239|Firmicutes,24Y6R@186801|Clostridia,27KHZ@186928|unclassified Lachnospiraceae	186801|Clostridia	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	-	-	-	-	-	-	-	-	-	FliD_C
KFPFDFKC_03427	585394.RHOM_06765	8.31e-58	181.0	COG1725@1|root,COG1725@2|Bacteria,1VA2B@1239|Firmicutes,24N57@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, GntR family	-	-	-	-	-	-	-	-	-	-	-	-	GntR
KFPFDFKC_03428	585394.RHOM_06760	7.49e-130	372.0	COG1131@1|root,COG1131@2|Bacteria,1TPUP@1239|Firmicutes,249FR@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
KFPFDFKC_03429	585394.RHOM_06755	1.56e-61	202.0	COG1131@1|root,COG1131@2|Bacteria,1VF25@1239|Firmicutes,248Y7@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03430	622312.ROSEINA2194_00367	0.0	939.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	E1-E2_ATPase,Hydrolase
KFPFDFKC_03431	585394.RHOM_06750	4.16e-313	855.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia	186801|Clostridia	C	'glutamate synthase	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
KFPFDFKC_03432	622312.ROSEINA2194_00370	9.43e-202	559.0	COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,247YB@186801|Clostridia	186801|Clostridia	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	pyrK_1	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146,R10159	RC00065	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
KFPFDFKC_03433	585394.RHOM_06740	5.41e-162	457.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia	186801|Clostridia	S	Abc transporter	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
KFPFDFKC_03434	585394.RHOM_06735	1.78e-179	505.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia	186801|Clostridia	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
KFPFDFKC_03435	622312.ROSEINA2194_00374	5.58e-160	461.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia	186801|Clostridia	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
KFPFDFKC_03436	622312.ROSEINA2194_04232	1.34e-130	378.0	COG2703@1|root,COG2703@2|Bacteria,1VBEC@1239|Firmicutes,24NV2@186801|Clostridia	186801|Clostridia	P	Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
KFPFDFKC_03437	585394.RHOM_06720	6.96e-196	546.0	COG0523@1|root,COG3689@1|root,COG0523@2|Bacteria,COG3689@2|Bacteria,1TS8P@1239|Firmicutes,248DY@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	cobW
KFPFDFKC_03438	622312.ROSEINA2194_03581	3.17e-194	548.0	COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia	186801|Clostridia	K	CobW P47K family protein	cobW	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
KFPFDFKC_03439	622312.ROSEINA2194_03578	0.0	941.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
KFPFDFKC_03440	585394.RHOM_06705	5.14e-116	336.0	COG1139@1|root,COG1139@2|Bacteria,1TP90@1239|Firmicutes,249B6@186801|Clostridia	186801|Clostridia	C	PFAM Uncharacterised ACR, YkgG family COG1556	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom
KFPFDFKC_03442	585394.RHOM_06700	3.98e-29	104.0	COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,24QP9@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
KFPFDFKC_03443	180332.JTGN01000001_gene5293	8.12e-05	52.8	COG5492@1|root,COG5492@2|Bacteria,1TQGW@1239|Firmicutes,25END@186801|Clostridia	186801|Clostridia	N	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430
KFPFDFKC_03444	585394.RHOM_06695	7.69e-95	298.0	COG0840@1|root,COG0840@2|Bacteria	2|Bacteria	NT	transmembrane signaling receptor activity	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1,sCache_2
KFPFDFKC_03445	622312.ROSEINA2194_03291	0.0	1544.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
KFPFDFKC_03447	622312.ROSEINA2194_03293	5.85e-141	402.0	COG2220@1|root,COG2220@2|Bacteria,1V3HY@1239|Firmicutes,24HK9@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	folD4	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
KFPFDFKC_03448	585394.RHOM_06675	1.68e-293	803.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia	186801|Clostridia	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31,3.5.4.40	ko:K12960,ko:K20810	ko00130,ko00270,ko01100,ko01110,map00130,map00270,map01100,map01110	-	R09660,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
KFPFDFKC_03449	585394.RHOM_06670	5.9e-172	483.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,247KQ@186801|Clostridia	186801|Clostridia	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
KFPFDFKC_03450	585394.RHOM_06660	5.38e-60	194.0	2DY6R@1|root,32V4T@2|Bacteria,1VDMI@1239|Firmicutes,24D1Z@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03451	585394.RHOM_06665	4.4e-102	301.0	COG2364@1|root,COG2364@2|Bacteria,1V7N6@1239|Firmicutes,25CWQ@186801|Clostridia	186801|Clostridia	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03452	585394.RHOM_06645	8.25e-268	744.0	COG0699@1|root,COG0699@2|Bacteria,1TPPG@1239|Firmicutes,24829@186801|Clostridia	186801|Clostridia	S	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	spoIVA	GO:0000003,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0008144,GO:0008150,GO:0009653,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019954,GO:0030154,GO:0030312,GO:0030435,GO:0030436,GO:0030554,GO:0031160,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0034301,GO:0035639,GO:0036094,GO:0042601,GO:0042763,GO:0043167,GO:0043168,GO:0043934,GO:0043936,GO:0044464,GO:0048646,GO:0048856,GO:0048869,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K06398	-	-	-	-	ko00000	-	-	-	Spore_IV_A
KFPFDFKC_03453	585394.RHOM_06640	7.59e-136	395.0	COG1597@1|root,COG1597@2|Bacteria,1V7DZ@1239|Firmicutes,25CN5@186801|Clostridia	186801|Clostridia	I	Diacylglycerol kinase catalytic domain	ytlR	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
KFPFDFKC_03454	622312.ROSEINA2194_01766	7.61e-315	863.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia	186801|Clostridia	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
KFPFDFKC_03455	585394.RHOM_06630	5.88e-193	541.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
KFPFDFKC_03456	585394.RHOM_06625	3.01e-178	499.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia	186801|Clostridia	P	sugar transport system permease	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
KFPFDFKC_03457	622312.ROSEINA2194_01763	7.84e-184	513.0	COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,24ADV@186801|Clostridia	186801|Clostridia	P	Abc transporter, permease protein	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
KFPFDFKC_03458	622312.ROSEINA2194_01762	8.92e-279	770.0	COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia	186801|Clostridia	G	ABC transporter, solute-binding protein	amyE	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8,TAT_signal
KFPFDFKC_03459	622312.ROSEINA2194_01760	1.03e-257	711.0	COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,247R4@186801|Clostridia	186801|Clostridia	P	Chloride transporter, ClC family	clcA	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
KFPFDFKC_03461	585394.RHOM_06585	1.92e-79	242.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HPU@186801|Clostridia	186801|Clostridia	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
KFPFDFKC_03462	585394.RHOM_06580	3.17e-219	607.0	COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,248F3@186801|Clostridia	186801|Clostridia	EJ	L-asparaginase	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
KFPFDFKC_03463	622312.ROSEINA2194_01198	1.23e-206	576.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,248TR@186801|Clostridia	186801|Clostridia	E	Beta-eliminating lyase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
KFPFDFKC_03464	585394.RHOM_06570	5.55e-179	505.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia	186801|Clostridia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
KFPFDFKC_03465	585394.RHOM_06565	2.36e-137	394.0	COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,248M2@186801|Clostridia	186801|Clostridia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
KFPFDFKC_03466	585394.RHOM_06560	4.24e-256	706.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,24881@186801|Clostridia	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20,5.3.1.24	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03509	RC00209,RC00210,RC00700,RC00701,RC00945,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,PRAI
KFPFDFKC_03467	697329.Rumal_1862	1.74e-46	160.0	COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,24HBQ@186801|Clostridia,3WM7Q@541000|Ruminococcaceae	186801|Clostridia	E	N-(5'phosphoribosyl)anthranilate (PRA) isomerase	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
KFPFDFKC_03468	585394.RHOM_06550	8.96e-127	367.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,249ZY@186801|Clostridia	186801|Clostridia	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
KFPFDFKC_03469	585394.RHOM_06545	1.98e-113	327.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,24FR0@186801|Clostridia	186801|Clostridia	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
KFPFDFKC_03470	585394.RHOM_06540	5.7e-268	743.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia	186801|Clostridia	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
KFPFDFKC_03471	536233.CLO_3167	4.03e-23	101.0	COG1763@1|root,COG1763@2|Bacteria,1VAIZ@1239|Firmicutes,24N6J@186801|Clostridia,36UPV@31979|Clostridiaceae	186801|Clostridia	H	selenium-dependent hydroxylase accessory protein YqeC	yqeC	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03472	483218.BACPEC_02162	6.05e-07	52.4	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
KFPFDFKC_03473	622312.ROSEINA2194_01205	0.0	1191.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia	186801|Clostridia	G	alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
KFPFDFKC_03474	585394.RHOM_06420	4.54e-260	721.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,247VA@186801|Clostridia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	lacS	-	-	ko:K03292,ko:K11104,ko:K16209	-	-	-	-	ko00000,ko02000	2.A.2,2.A.2.1,2.A.2.2	-	-	MFS_2
KFPFDFKC_03475	585394.RHOM_06415	2.29e-289	797.0	2BZA3@1|root,2Z7YV@2|Bacteria,1TSER@1239|Firmicutes,24AF5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03476	1235800.C819_03666	0.0	1090.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,249UZ@186801|Clostridia,27TNA@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolases family 2, TIM barrel domain	lacZ	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
KFPFDFKC_03477	585394.RHOM_06405	6.83e-98	288.0	COG1309@1|root,COG1309@2|Bacteria,1V7SY@1239|Firmicutes,24JI6@186801|Clostridia	186801|Clostridia	K	transcriptional regulator TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
KFPFDFKC_03478	585394.RHOM_06400	1.08e-147	419.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia	186801|Clostridia	S	(AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
KFPFDFKC_03479	585394.RHOM_06395	8.01e-165	480.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,247ZH@186801|Clostridia	186801|Clostridia	P	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
KFPFDFKC_03481	471875.RUMLAC_00916	6.1e-101	293.0	COG0454@1|root,COG0456@2|Bacteria,1V77V@1239|Firmicutes,24HI8@186801|Clostridia,3WIP1@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
KFPFDFKC_03482	585394.RHOM_13415	1.3e-111	321.0	COG4732@1|root,COG4732@2|Bacteria,1V6HH@1239|Firmicutes,24JF7@186801|Clostridia	186801|Clostridia	S	ThiW protein	thiW	-	-	-	-	-	-	-	-	-	-	-	ThiW
KFPFDFKC_03483	585394.RHOM_13420	4.6e-245	677.0	COG1457@1|root,COG1457@2|Bacteria,1TTBN@1239|Firmicutes,248EP@186801|Clostridia	186801|Clostridia	F	PFAM Permease for cytosine purines, uracil, thiamine, allantoin	cytX	-	-	-	-	-	-	-	-	-	-	-	Transp_cyt_pur
KFPFDFKC_03484	622312.ROSEINA2194_00222	1.17e-175	491.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,2483H@186801|Clostridia	186801|Clostridia	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
KFPFDFKC_03485	1410630.JNKP01000002_gene1639	1.75e-109	320.0	COG0500@1|root,COG0500@2|Bacteria,1V0PR@1239|Firmicutes,25E3Q@186801|Clostridia,27IRT@186928|unclassified Lachnospiraceae	186801|Clostridia	Q	Protein of unknown function (DUF1698)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
KFPFDFKC_03486	411489.CLOL250_00372	4e-232	644.0	COG0642@1|root,COG2205@2|Bacteria,1UHQC@1239|Firmicutes,2496X@186801|Clostridia,36HCI@31979|Clostridiaceae	186801|Clostridia	T	Signal transduction histidine kinase	arlS	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
KFPFDFKC_03487	411474.COPEUT_01943	8.25e-138	392.0	COG0745@1|root,COG0745@2|Bacteria,1TSRR@1239|Firmicutes,24AG3@186801|Clostridia	186801|Clostridia	T	Psort location Cytoplasmic, score	cutR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
KFPFDFKC_03488	1256908.HMPREF0373_00304	4.17e-188	525.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,25V01@186806|Eubacteriaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
KFPFDFKC_03489	411461.DORFOR_03149	1.7e-101	306.0	COG0526@1|root,COG0526@2|Bacteria,1UY9A@1239|Firmicutes,24C03@186801|Clostridia,27WII@189330|Dorea	186801|Clostridia	M	COG COG0526 Thiol-disulfide isomerase and THIoredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
KFPFDFKC_03490	585394.RHOM_13440	5.34e-160	454.0	28KEH@1|root,2ZA0R@2|Bacteria,1V76J@1239|Firmicutes,24JHU@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4300)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4300
KFPFDFKC_03491	585394.RHOM_06390	2.96e-55	179.0	2EF5Q@1|root,338YV@2|Bacteria,1VJS5@1239|Firmicutes,24RWV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03492	585394.RHOM_06380	5.43e-179	501.0	COG0685@1|root,COG0685@2|Bacteria,1TQFE@1239|Firmicutes,247ZK@186801|Clostridia	186801|Clostridia	E	5,10-methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
KFPFDFKC_03493	585394.RHOM_06375	5.92e-102	296.0	COG0782@1|root,COG0782@2|Bacteria,1V1G3@1239|Firmicutes,24FRJ@186801|Clostridia	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA_2	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
KFPFDFKC_03494	2325.TKV_c09470	1.65e-25	106.0	COG2091@1|root,COG2091@2|Bacteria,1VEYZ@1239|Firmicutes,24RQ3@186801|Clostridia,42GYT@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the P-Pant transferase superfamily	sfp	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
KFPFDFKC_03495	585394.RHOM_06365	2.45e-36	127.0	COG2198@1|root,COG2198@2|Bacteria,1VGD4@1239|Firmicutes,25CZI@186801|Clostridia	186801|Clostridia	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
KFPFDFKC_03496	585394.RHOM_06360	5.66e-270	774.0	COG2199@1|root,COG2200@1|root,COG2200@2|Bacteria,COG3706@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,Response_reg
KFPFDFKC_03497	642492.Clole_1639	9.19e-305	856.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia	186801|Clostridia	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
KFPFDFKC_03498	357809.Cphy_0218	0.0	1189.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,21YQ6@1506553|Lachnoclostridium	186801|Clostridia	G	Galactose mutarotase-like	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,Gal_mutarotas_2,Glyco_hydro_31
KFPFDFKC_03499	1195236.CTER_3491	5.65e-205	586.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V4UB@1239|Firmicutes,24BJM@186801|Clostridia,3WRKI@541000|Ruminococcaceae	186801|Clostridia	K	PFAM response regulator receiver	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
KFPFDFKC_03500	1469948.JPNB01000001_gene966	0.0	886.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,36E82@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
KFPFDFKC_03501	1469948.JPNB01000001_gene965	1.23e-306	849.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,36DEY@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
KFPFDFKC_03502	180332.JTGN01000001_gene4817	3.71e-96	291.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1V2EN@1239|Firmicutes,24GG9@186801|Clostridia	186801|Clostridia	K	PFAM helix-turn-helix- domain containing protein AraC type	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
KFPFDFKC_03503	1408423.JHYA01000010_gene1428	1.04e-260	722.0	COG1373@1|root,COG1373@2|Bacteria,1TQ8Z@1239|Firmicutes,4H24U@909932|Negativicutes	909932|Negativicutes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
KFPFDFKC_03504	1256908.HMPREF0373_00590	2.57e-133	379.0	2DD90@1|root,2ZH3Q@2|Bacteria,1V1HB@1239|Firmicutes,24GNM@186801|Clostridia,25YGQ@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function, E. rectale Gene description (DUF3879)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3879
KFPFDFKC_03505	483218.BACPEC_02677	1.76e-50	167.0	28S3E@1|root,335CC@2|Bacteria,1VHAF@1239|Firmicutes,24TDZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03506	483218.BACPEC_01771	1.66e-92	273.0	2DWFF@1|root,32V1I@2|Bacteria,1VDEW@1239|Firmicutes,24PX0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03507	483218.BACPEC_01771	3.72e-29	108.0	2DWFF@1|root,32V1I@2|Bacteria,1VDEW@1239|Firmicutes,24PX0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03508	483218.BACPEC_01770	2.02e-169	474.0	2AE4I@1|root,313XT@2|Bacteria,1V86Q@1239|Firmicutes,24KFS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03509	483218.BACPEC_01769	1.03e-101	298.0	2B7HH@1|root,320MM@2|Bacteria,1V7BY@1239|Firmicutes,24KSD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03510	483218.BACPEC_01768	1.82e-164	462.0	COG1345@1|root,COG1345@2|Bacteria,1V1XI@1239|Firmicutes,24GW8@186801|Clostridia	186801|Clostridia	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03511	515620.EUBELI_00193	4.21e-153	435.0	COG4223@1|root,COG4223@2|Bacteria,1V01S@1239|Firmicutes,249JR@186801|Clostridia,25WJS@186806|Eubacteriaceae	186801|Clostridia	S	FlxA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	FlxA
KFPFDFKC_03512	515620.EUBELI_00191	0.0	870.0	COG3290@1|root,COG3290@2|Bacteria,1TRW9@1239|Firmicutes,24D9R@186801|Clostridia,25W5A@186806|Eubacteriaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,SPOB_a
KFPFDFKC_03513	483218.BACPEC_01765	2.66e-164	461.0	COG3279@1|root,COG3279@2|Bacteria,1TSDB@1239|Firmicutes,24MQ4@186801|Clostridia,269MD@186813|unclassified Clostridiales	186801|Clostridia	KT	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
KFPFDFKC_03514	1235800.C819_00414	3.86e-122	351.0	2E6Z2@1|root,331I9@2|Bacteria,1VJP0@1239|Firmicutes,24YM6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03515	483218.BACPEC_02677	2.36e-88	266.0	28S3E@1|root,335CC@2|Bacteria,1VHAF@1239|Firmicutes,24TDZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03517	511680.BUTYVIB_02361	5.72e-103	303.0	290UV@1|root,2ZNGV@2|Bacteria,1V2HB@1239|Firmicutes,24GF7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03518	1235800.C819_01439	1.41e-95	295.0	2EVV1@1|root,33P8S@2|Bacteria,1VNF6@1239|Firmicutes,24VSM@186801|Clostridia,27N91@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03519	622312.ROSEINA2194_01178	6.53e-06	47.0	2DB9G@1|root,2Z7WS@2|Bacteria,1TRCU@1239|Firmicutes,24EEG@186801|Clostridia	186801|Clostridia	S	Domain of unknown function, E. rectale Gene description (DUF3879)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3879
KFPFDFKC_03520	515620.EUBELI_20007	4.07e-100	296.0	29EZB@1|root,301X4@2|Bacteria,1V54H@1239|Firmicutes,24I4P@186801|Clostridia,25YN8@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03521	397291.C804_05921	6.82e-24	100.0	2DVXT@1|root,33XMK@2|Bacteria,1VWBJ@1239|Firmicutes,251C0@186801|Clostridia,27M7C@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03522	483218.BACPEC_01770	1.33e-154	437.0	2AE4I@1|root,313XT@2|Bacteria,1V86Q@1239|Firmicutes,24KFS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03523	483218.BACPEC_00110	4.14e-50	170.0	28KQP@1|root,314YH@2|Bacteria,1V8JK@1239|Firmicutes,24EPX@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4885
KFPFDFKC_03524	585394.RHOM_16350	1.23e-201	570.0	COG3290@1|root,COG3290@2|Bacteria,1V225@1239|Firmicutes,24DB7@186801|Clostridia	186801|Clostridia	T	signal transduction protein with a C-terminal ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
KFPFDFKC_03525	585394.RHOM_16355	3.54e-97	291.0	COG3279@1|root,COG3279@2|Bacteria,1V217@1239|Firmicutes,24GJ1@186801|Clostridia	186801|Clostridia	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
KFPFDFKC_03527	1235800.C819_00815	1.64e-258	730.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,27J4S@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Domain of unknown function (DUF4368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
KFPFDFKC_03529	397291.C804_05879	3.36e-63	203.0	28JS8@1|root,2Z9HS@2|Bacteria,1UY4F@1239|Firmicutes,248MI@186801|Clostridia,27IR8@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03530	622312.ROSEINA2194_01195	4.09e-216	597.0	COG5464@1|root,COG5464@2|Bacteria,1UA0N@1239|Firmicutes,247X9@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
KFPFDFKC_03531	1235793.C809_02425	3.23e-45	149.0	2C5R4@1|root,31VPY@2|Bacteria,1V8EP@1239|Firmicutes,24JPJ@186801|Clostridia,27MNA@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
KFPFDFKC_03532	518637.EUBIFOR_01475	7.09e-19	84.3	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,3VQ8R@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Oxidoreductase, aldo keto reductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
KFPFDFKC_03533	596153.Alide_1289	2.12e-05	49.3	COG0834@1|root,COG2199@1|root,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VMMZ@28216|Betaproteobacteria,4ACWB@80864|Comamonadaceae	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_3,PAS_4,Response_reg,SBP_bac_3,dCache_1
KFPFDFKC_03535	622312.ROSEINA2194_04371	2.92e-172	485.0	COG1284@1|root,COG1284@2|Bacteria,1TYTP@1239|Firmicutes,25CBP@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
KFPFDFKC_03536	397291.C804_04805	3.95e-210	593.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,27IAA@186928|unclassified Lachnospiraceae	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
KFPFDFKC_03537	556261.HMPREF0240_03527	0.0	917.0	COG4637@1|root,COG4637@2|Bacteria,1UZCB@1239|Firmicutes,248WE@186801|Clostridia,36PCY@31979|Clostridiaceae	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
KFPFDFKC_03538	397287.C807_02411	7.26e-84	253.0	COG4720@1|root,COG4720@2|Bacteria,1V5I7@1239|Firmicutes,25CJU@186801|Clostridia,27U5H@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Pfam:DUF3816	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
KFPFDFKC_03539	585394.RHOM_05960	1.18e-220	623.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1TPGQ@1239|Firmicutes,247N0@186801|Clostridia	186801|Clostridia	J	NOL1 NOP2 sun family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
KFPFDFKC_03540	1235793.C809_02152	6.49e-207	579.0	COG4804@1|root,COG4804@2|Bacteria,1TP7Q@1239|Firmicutes,24A19@186801|Clostridia,27TF6@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF1016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
KFPFDFKC_03541	1226325.HMPREF1548_02362	8.29e-232	644.0	COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,248AY@186801|Clostridia,36DKQ@31979|Clostridiaceae	186801|Clostridia	E	PFAM Aminotransferase class I and II	-	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
KFPFDFKC_03542	658086.HMPREF0994_00210	0.0	897.0	COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,248WN@186801|Clostridia,27TF9@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Na+/H+ antiporter family	nhaC	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
KFPFDFKC_03543	658086.HMPREF0994_00211	4.79e-63	195.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,27N9W@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
KFPFDFKC_03544	1226325.HMPREF1548_02366	3.31e-123	355.0	COG2964@1|root,COG2964@2|Bacteria,1V33R@1239|Firmicutes,25CHI@186801|Clostridia,36WW5@31979|Clostridiaceae	186801|Clostridia	S	HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_22,PAS_6
KFPFDFKC_03545	1226325.HMPREF1548_03838	8.84e-06	44.7	2BEGM@1|root,3287Y@2|Bacteria,1UU58@1239|Firmicutes,255IQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03547	585394.RHOM_05940	6.02e-24	93.2	2EHJU@1|root,33BBQ@2|Bacteria,1VN8N@1239|Firmicutes,24VAU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03548	1469948.JPNB01000001_gene2285	0.0	1109.0	COG0480@1|root,COG3688@1|root,COG0480@2|Bacteria,COG3688@2|Bacteria,1TPQH@1239|Firmicutes,247X4@186801|Clostridia,36DHY@31979|Clostridiaceae	186801|Clostridia	J	elongation factor G	tetP	-	-	-	-	-	-	-	-	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,NYN_YacP
KFPFDFKC_03549	350688.Clos_2061	1.03e-25	113.0	28NDR@1|root,2ZBGG@2|Bacteria,1TSYU@1239|Firmicutes,24E7Y@186801|Clostridia,36PP2@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03550	515620.EUBELI_00659	9.96e-239	667.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,25VPU@186806|Eubacteriaceae	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
KFPFDFKC_03551	428125.CLOLEP_01728	0.0	1311.0	COG0178@1|root,COG0178@2|Bacteria,1TP0A@1239|Firmicutes,24B3G@186801|Clostridia,3WN9G@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
KFPFDFKC_03554	585394.RHOM_05930	8.43e-302	835.0	COG3044@1|root,COG3044@2|Bacteria,1TPJ9@1239|Firmicutes,248G5@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_ATPase
KFPFDFKC_03555	556261.HMPREF0240_03393	3.79e-93	293.0	COG4924@1|root,COG4924@2|Bacteria,1V0BQ@1239|Firmicutes,24DRK@186801|Clostridia,36PW8@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function C-terminus (DUF2399)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2220,DUF3322
KFPFDFKC_03556	1226325.HMPREF1548_05145	0.0	1425.0	COG4913@1|root,COG4913@2|Bacteria,1TPVZ@1239|Firmicutes,2491E@186801|Clostridia,36EUY@31979|Clostridiaceae	186801|Clostridia	S	DNA replication and repair protein RecF	-	-	-	-	-	-	-	-	-	-	-	-	AAA_29,SMC_hinge,SbcCD_C
KFPFDFKC_03557	1226325.HMPREF1548_05144	3.42e-87	266.0	2A92C@1|root,30Y6D@2|Bacteria,1V59Y@1239|Firmicutes,25HP5@186801|Clostridia,36I7M@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF4194)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4194
KFPFDFKC_03558	658086.HMPREF0994_07307	6.5e-208	590.0	28JJB@1|root,2Z9CE@2|Bacteria,1U6BP@1239|Firmicutes,24B0T@186801|Clostridia,27UAP@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03559	515620.EUBELI_00163	9.4e-278	768.0	COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,247NY@186801|Clostridia,25URI@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C,QRPTase_N
KFPFDFKC_03560	585394.RHOM_05925	3.31e-242	679.0	COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,248X1@186801|Clostridia	186801|Clostridia	S	associated with various cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
KFPFDFKC_03561	357809.Cphy_2058	1.57e-153	451.0	COG2730@1|root,COG2730@2|Bacteria,1UVAD@1239|Firmicutes,25KF9@186801|Clostridia,223EG@1506553|Lachnoclostridium	186801|Clostridia	G	Cellulase (glycosyl hydrolase family 5)	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
KFPFDFKC_03562	585394.RHOM_11440	1.79e-223	618.0	COG2152@1|root,COG2152@2|Bacteria,1TQE7@1239|Firmicutes,249D0@186801|Clostridia	186801|Clostridia	G	PFAM Glycosidase	-	-	2.4.1.319,2.4.1.320	ko:K18785	-	-	R10811,R10829	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
KFPFDFKC_03563	1449050.JNLE01000003_gene2847	1.13e-101	309.0	COG1609@1|root,COG1609@2|Bacteria,1TT55@1239|Firmicutes,24A7X@186801|Clostridia,36HMC@31979|Clostridiaceae	186801|Clostridia	K	PFAM Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
KFPFDFKC_03564	357809.Cphy_2275	3.79e-40	143.0	COG5578@1|root,COG5578@2|Bacteria,1VI97@1239|Firmicutes,24TB6@186801|Clostridia	186801|Clostridia	S	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
KFPFDFKC_03565	1094508.Tsac_1165	1.21e-129	392.0	COG1653@1|root,COG1653@2|Bacteria,1TXES@1239|Firmicutes,25JZ6@186801|Clostridia,42INH@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM Bacterial extracellular solute-binding	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	-
KFPFDFKC_03566	1121335.Clst_1084	4.38e-129	378.0	COG0395@1|root,COG0395@2|Bacteria,1UYH5@1239|Firmicutes,24AMA@186801|Clostridia,3WH39@541000|Ruminococcaceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
KFPFDFKC_03567	1121335.Clst_1083	3.69e-120	353.0	COG1175@1|root,COG1175@2|Bacteria,1U73Q@1239|Firmicutes,24AFP@186801|Clostridia,3WHI4@541000|Ruminococcaceae	186801|Clostridia	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
KFPFDFKC_03568	1121335.Clst_1082	2.68e-274	789.0	COG3420@1|root,COG3420@2|Bacteria,1TSNZ@1239|Firmicutes,24D4T@186801|Clostridia,3WHC4@541000|Ruminococcaceae	186801|Clostridia	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03569	1121335.Clst_1081	1.64e-69	218.0	COG2881@1|root,COG2881@2|Bacteria,1VBWZ@1239|Firmicutes,24MD2@186801|Clostridia	186801|Clostridia	S	overlaps another CDS with the same product name	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
KFPFDFKC_03570	1094508.Tsac_1160	1.4e-176	512.0	COG3391@1|root,COG3391@2|Bacteria,1U3IC@1239|Firmicutes,2490J@186801|Clostridia,42I05@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL,Yip1
KFPFDFKC_03571	1121335.Clst_1079	3.45e-156	444.0	COG0395@1|root,COG0395@2|Bacteria,1TRS1@1239|Firmicutes,24ARW@186801|Clostridia,3WH53@541000|Ruminococcaceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
KFPFDFKC_03572	1449050.JNLE01000003_gene2908	1.82e-157	449.0	COG1175@1|root,COG1175@2|Bacteria,1TR0M@1239|Firmicutes,24CRB@186801|Clostridia	186801|Clostridia	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
KFPFDFKC_03573	1121335.Clst_1077	0.0	1136.0	COG2182@1|root,COG2182@2|Bacteria,1UJPM@1239|Firmicutes,25F7T@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
KFPFDFKC_03574	1226325.HMPREF1548_03052	1.63e-34	134.0	COG3250@1|root,COG3250@2|Bacteria,1TU92@1239|Firmicutes,248WD@186801|Clostridia,36FQK@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
KFPFDFKC_03575	622312.ROSEINA2194_00480	2.09e-201	571.0	COG3864@1|root,COG3864@2|Bacteria,1TSI1@1239|Firmicutes,248YT@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
KFPFDFKC_03576	585394.RHOM_09385	1.2e-73	239.0	2DMDS@1|root,32QT4@2|Bacteria,1UINH@1239|Firmicutes,25EP3@186801|Clostridia	186801|Clostridia	S	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
KFPFDFKC_03577	622312.ROSEINA2194_02007	3.25e-143	414.0	COG0523@1|root,COG0523@2|Bacteria,1TQRE@1239|Firmicutes,24B0I@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
KFPFDFKC_03578	1235802.C823_03877	8.11e-184	525.0	COG2866@1|root,COG3409@1|root,COG2866@2|Bacteria,COG3409@2|Bacteria,1TP3K@1239|Firmicutes,249MT@186801|Clostridia,25WZ3@186806|Eubacteriaceae	186801|Clostridia	E	Zn_pept	-	-	3.4.19.11	ko:K01308	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	LysM,PG_binding_1,Peptidase_M14
KFPFDFKC_03579	1235790.C805_02517	2.22e-148	457.0	COG4188@1|root,COG4188@2|Bacteria,1UGK7@1239|Firmicutes,24CXP@186801|Clostridia	186801|Clostridia	S	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase2
KFPFDFKC_03580	585394.RHOM_13045	5.38e-275	773.0	COG1609@1|root,COG2199@1|root,COG1609@2|Bacteria,COG3706@2|Bacteria,1TSMK@1239|Firmicutes,24EJV@186801|Clostridia	186801|Clostridia	KT	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Peripla_BP_3
KFPFDFKC_03581	622312.ROSEINA2194_01540	5.61e-127	361.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
KFPFDFKC_03582	585394.RHOM_05110	2.97e-95	278.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia	186801|Clostridia	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
KFPFDFKC_03583	585394.RHOM_05105	9.23e-102	296.0	COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,24KK7@186801|Clostridia	186801|Clostridia	F	HAD superfamily (Subfamily IIIA) phosphatase, TIGR01668	yqeG	-	-	ko:K07015	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase
KFPFDFKC_03584	585394.RHOM_05100	3e-31	114.0	2E9G7@1|root,333PE@2|Bacteria,1VHIP@1239|Firmicutes,24UC4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03585	585394.RHOM_05095	7.84e-101	292.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
KFPFDFKC_03586	585394.RHOM_05090	1.74e-42	140.0	COG1873@1|root,COG1873@2|Bacteria,1VEMT@1239|Firmicutes	1239|Firmicutes	S	sporulation protein, YlmC YmxH family	ylmC	-	-	-	-	-	-	-	-	-	-	-	PRC
KFPFDFKC_03587	622312.ROSEINA2194_03519	5.19e-252	692.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
KFPFDFKC_03588	665956.HMPREF1032_03443	9.53e-24	109.0	COG4974@1|root,COG4974@2|Bacteria,1V5BG@1239|Firmicutes,25ETT@186801|Clostridia,3WSJI@541000|Ruminococcaceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
KFPFDFKC_03590	511680.BUTYVIB_02187	1.14e-180	512.0	COG3437@1|root,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,4BXK7@830|Butyrivibrio	186801|Clostridia	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
KFPFDFKC_03592	411459.RUMOBE_02040	2.48e-43	144.0	COG2198@1|root,COG2198@2|Bacteria,1TUB6@1239|Firmicutes,257TB@186801|Clostridia,3Y0UT@572511|Blautia	186801|Clostridia	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
KFPFDFKC_03593	585394.RHOM_09975	4.5e-88	266.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia	186801|Clostridia	H	thiamine pyrophosphokinase	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
KFPFDFKC_03594	585394.RHOM_09980	3.28e-128	367.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia	186801|Clostridia	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
KFPFDFKC_03595	585394.RHOM_09985	2.14e-162	460.0	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,248R5@186801|Clostridia	186801|Clostridia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
KFPFDFKC_03596	585394.RHOM_09990	7.26e-285	803.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia	186801|Clostridia	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
KFPFDFKC_03597	622312.ROSEINA2194_03525	2.75e-126	365.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia	186801|Clostridia	T	Phosphatase	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
KFPFDFKC_03598	622312.ROSEINA2194_03526	1.26e-211	589.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
KFPFDFKC_03599	622312.ROSEINA2194_03527	2.65e-200	568.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia	186801|Clostridia	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
KFPFDFKC_03600	622312.ROSEINA2194_03528	4.26e-143	406.0	COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,2490Y@186801|Clostridia	186801|Clostridia	S	zinc metallopeptidase	yugP	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
KFPFDFKC_03601	585394.RHOM_10015	5.63e-178	501.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
KFPFDFKC_03602	622312.ROSEINA2194_03530	7.57e-91	268.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,24JET@186801|Clostridia	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
KFPFDFKC_03603	585394.RHOM_10025	0.0	1028.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
KFPFDFKC_03604	585394.RHOM_10030	4.5e-219	622.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
KFPFDFKC_03605	622312.ROSEINA2194_00386	6.19e-307	852.0	COG2604@1|root,COG2604@2|Bacteria,1U2BC@1239|Firmicutes,24CSU@186801|Clostridia	186801|Clostridia	S	Protein of unknown function DUF115	-	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10
KFPFDFKC_03607	478749.BRYFOR_05995	3.54e-183	510.0	COG3315@1|root,COG3315@2|Bacteria,1UPJI@1239|Firmicutes,24BUU@186801|Clostridia	186801|Clostridia	Q	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	LCM
KFPFDFKC_03608	1280671.AUJH01000028_gene895	3.83e-32	115.0	2CU1H@1|root,32SUI@2|Bacteria,1VB8S@1239|Firmicutes,24PZC@186801|Clostridia,4C0G3@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03609	1280698.AUJS01000042_gene3268	1.38e-75	225.0	COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,25NNG@186801|Clostridia,27X9B@189330|Dorea	186801|Clostridia	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
KFPFDFKC_03610	411459.RUMOBE_01921	1.19e-77	231.0	COG0662@1|root,COG0662@2|Bacteria,1V7HI@1239|Firmicutes,24JQZ@186801|Clostridia	186801|Clostridia	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
KFPFDFKC_03611	1163671.JAGI01000002_gene3494	7.18e-43	144.0	2EBMR@1|root,335MY@2|Bacteria,1VHUF@1239|Firmicutes,24VP4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03612	622312.ROSEINA2194_03927	3.17e-44	168.0	COG3501@1|root,COG3501@2|Bacteria,1V3I5@1239|Firmicutes,24GKG@186801|Clostridia	186801|Clostridia	F	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
KFPFDFKC_03613	679200.HMPREF9333_01947	6.68e-172	484.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia	186801|Clostridia	K	Belongs to the ParB family	-	-	-	-	-	-	-	-	-	-	-	-	DUF5348,ParBc
KFPFDFKC_03614	936596.HMPREF1495_1511	1.53e-154	437.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,247R1@186801|Clostridia,1HW9U@1164882|Lachnoanaerobaculum	186801|Clostridia	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
KFPFDFKC_03615	1095750.HMPREF9970_2043	1.5e-26	97.8	2C7EF@1|root,32B2X@2|Bacteria,1UH1V@1239|Firmicutes,25PQ5@186801|Clostridia,1HWGT@1164882|Lachnoanaerobaculum	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03618	622312.ROSEINA2194_03927	2.5e-38	142.0	COG3501@1|root,COG3501@2|Bacteria,1V3I5@1239|Firmicutes,24GKG@186801|Clostridia	186801|Clostridia	F	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
KFPFDFKC_03619	1196029.ALIM01000001_gene4937	7.72e-44	159.0	COG2369@1|root,COG2369@2|Bacteria,1V7DS@1239|Firmicutes,4HRJV@91061|Bacilli	91061|Bacilli	K	cell adhesion	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03620	272562.CA_C0134	5.76e-17	75.5	2CMHU@1|root,32SEU@2|Bacteria,1VDUI@1239|Firmicutes,251YF@186801|Clostridia,36S51@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03621	622312.ROSEINA2194_03927	1.67e-93	294.0	COG3501@1|root,COG3501@2|Bacteria,1V3I5@1239|Firmicutes,24GKG@186801|Clostridia	186801|Clostridia	F	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
KFPFDFKC_03623	180332.JTGN01000016_gene1038	0.0	991.0	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,2492T@186801|Clostridia	186801|Clostridia	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
KFPFDFKC_03624	500632.CLONEX_00864	9.12e-287	785.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
KFPFDFKC_03626	585394.RHOM_16355	9.76e-173	482.0	COG3279@1|root,COG3279@2|Bacteria,1V217@1239|Firmicutes,24GJ1@186801|Clostridia	186801|Clostridia	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
KFPFDFKC_03627	1280681.AUJZ01000026_gene388	2.67e-78	237.0	2DMYW@1|root,32UFQ@2|Bacteria,1UKTV@1239|Firmicutes,25G9Z@186801|Clostridia	186801|Clostridia	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
KFPFDFKC_03628	1235802.C823_03609	9.34e-219	607.0	COG0451@1|root,COG0451@2|Bacteria,1TQW7@1239|Firmicutes,24BI6@186801|Clostridia,25VIS@186806|Eubacteriaceae	186801|Clostridia	GM	RmlD substrate binding domain	rfbG	-	4.2.1.45	ko:K01709	ko00520,map00520	-	R02426	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
KFPFDFKC_03629	665956.HMPREF1032_01070	1.93e-172	488.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,24AAR@186801|Clostridia,3WGH6@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
KFPFDFKC_03630	1163671.JAGI01000002_gene3144	1.51e-185	523.0	COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,24AY7@186801|Clostridia,36F62@31979|Clostridiaceae	186801|Clostridia	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
KFPFDFKC_03631	1235802.C823_02170	2.26e-52	181.0	COG0451@1|root,COG0451@2|Bacteria,1UZR1@1239|Firmicutes,24DWP@186801|Clostridia,25W5I@186806|Eubacteriaceae	186801|Clostridia	GM	GDP-mannose 4,6 dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
KFPFDFKC_03632	411902.CLOBOL_04864	7.29e-166	476.0	COG2227@1|root,COG2227@2|Bacteria,1UYCW@1239|Firmicutes,24C7Q@186801|Clostridia,21Y0S@1506553|Lachnoclostridium	186801|Clostridia	H	C-methyltransferase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
KFPFDFKC_03633	658655.HMPREF0988_02467	0.0	996.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,248Z9@186801|Clostridia,27IBW@186928|unclassified Lachnospiraceae	186801|Clostridia	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
KFPFDFKC_03634	397291.C804_04439	6.4e-298	815.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,27JAE@186928|unclassified Lachnospiraceae	186801|Clostridia	M	DegT/DnrJ/EryC1/StrS aminotransferase family	rfbH	-	1.17.1.1	ko:K12452	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
KFPFDFKC_03635	553973.CLOHYLEM_06245	6.65e-170	476.0	COG1208@1|root,COG1208@2|Bacteria,1TPII@1239|Firmicutes,249GT@186801|Clostridia,21YI5@1506553|Lachnoclostridium	186801|Clostridia	JM	Nucleotidyl transferase	rfbF	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
KFPFDFKC_03636	1536773.R70331_28815	1.18e-29	130.0	28IM2@1|root,2Z8MM@2|Bacteria,1TSFR@1239|Firmicutes,4I9II@91061|Bacilli,271M6@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03637	720555.BATR1942_00670	7.41e-06	57.0	COG3594@1|root,COG3594@2|Bacteria,1VECK@1239|Firmicutes,4HNBZ@91061|Bacilli,1ZCGU@1386|Bacillus	91061|Bacilli	G	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
KFPFDFKC_03639	1232443.BAIA02000074_gene454	5.45e-19	89.7	COG1368@1|root,COG1368@2|Bacteria,1TQYQ@1239|Firmicutes,25CNS@186801|Clostridia,26AWT@186813|unclassified Clostridiales	186801|Clostridia	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
KFPFDFKC_03641	1163671.JAGI01000002_gene3189	1.21e-88	267.0	COG0279@1|root,COG0279@2|Bacteria,1V5W5@1239|Firmicutes,24INX@186801|Clostridia,36ICY@31979|Clostridiaceae	186801|Clostridia	G	isomerase	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
KFPFDFKC_03642	768704.Desmer_4161	2.43e-220	617.0	COG0241@1|root,COG1208@1|root,COG0241@2|Bacteria,COG1208@2|Bacteria,1VDBC@1239|Firmicutes,24AGU@186801|Clostridia,262B4@186807|Peptococcaceae	186801|Clostridia	JM	Nucleotidyl transferase	gmhB	-	2.7.7.13,2.7.7.71,3.1.3.82,3.1.3.83,5.4.2.8	ko:K03273,ko:K15669,ko:K16881	ko00051,ko00520,ko00540,ko01100,ko01110,ko01130,map00051,map00520,map00540,map01100,map01110,map01130	M00064,M00114,M00362	R00885,R01818,R05647,R09771,R09772	RC00002,RC00017,RC00408	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hydrolase_like,NTP_transferase,PGM_PMM_I,PGM_PMM_III,PNK3P
KFPFDFKC_03643	679200.HMPREF9333_00353	5.96e-183	515.0	COG2605@1|root,COG2605@2|Bacteria,1VU5A@1239|Firmicutes,24BK8@186801|Clostridia	186801|Clostridia	JM	GHMP kinase, N-terminal domain protein	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
KFPFDFKC_03644	457421.CBFG_02311	1.24e-260	789.0	COG0030@1|root,COG0438@1|root,COG1216@1|root,COG0030@2|Bacteria,COG0438@2|Bacteria,COG1216@2|Bacteria,1UVPZ@1239|Firmicutes,25KKM@186801|Clostridia,26CB6@186813|unclassified Clostridiales	186801|Clostridia	J	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03645	411473.RUMCAL_02184	1.83e-125	380.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia,3WHVP@541000|Ruminococcaceae	186801|Clostridia	GM	Psort location CytoplasmicMembrane, score	-	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
KFPFDFKC_03646	1304866.K413DRAFT_0290	4.23e-100	299.0	COG1682@1|root,COG1682@2|Bacteria,1TY8I@1239|Firmicutes,25B42@186801|Clostridia,36W8R@31979|Clostridiaceae	186801|Clostridia	U	Transport permease protein	-	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
KFPFDFKC_03647	411490.ANACAC_01035	6.22e-91	307.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,2480C@186801|Clostridia	186801|Clostridia	M	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
KFPFDFKC_03649	1441629.PCH70_03940	7.51e-43	150.0	COG1403@1|root,COG1403@2|Bacteria,1NIS7@1224|Proteobacteria,1SGK2@1236|Gammaproteobacteria,1Z7CC@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03650	97139.C824_02742	3.87e-80	261.0	COG3950@1|root,COG3950@2|Bacteria,1UYMB@1239|Firmicutes,24CS6@186801|Clostridia	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03651	1408436.JHXY01000001_gene565	8.65e-34	133.0	COG0463@1|root,COG0463@2|Bacteria,1V2TV@1239|Firmicutes,24NCK@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
KFPFDFKC_03652	1235800.C819_00558	5.27e-45	158.0	28QM1@1|root,2ZD2T@2|Bacteria,1UF6G@1239|Firmicutes,25K7D@186801|Clostridia,27S68@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03653	1235799.C818_01861	1.01e-140	410.0	COG4938@1|root,COG4938@2|Bacteria,1V5VH@1239|Firmicutes,24J2U@186801|Clostridia,27MT5@186928|unclassified Lachnospiraceae	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,DUF3696
KFPFDFKC_03654	1235802.C823_01905	5.17e-189	536.0	COG1479@1|root,COG1479@2|Bacteria,1V3XN@1239|Firmicutes,24PZA@186801|Clostridia,25YYZ@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262
KFPFDFKC_03655	632335.Calkr_2278	8.47e-90	284.0	COG0297@1|root,COG0297@2|Bacteria,1TQWW@1239|Firmicutes,25FJB@186801|Clostridia	186801|Clostridia	G	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
KFPFDFKC_03656	877421.AUJT01000004_gene2306	1.09e-88	269.0	COG1215@1|root,COG1215@2|Bacteria,1V4KD@1239|Firmicutes,24HZQ@186801|Clostridia,27KGG@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
KFPFDFKC_03657	1235798.C817_00116	2.88e-97	295.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	wbpV	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
KFPFDFKC_03658	1121289.JHVL01000007_gene2812	8.06e-108	316.0	COG2148@1|root,COG2148@2|Bacteria,1TQX9@1239|Firmicutes,24874@186801|Clostridia,36VHP@31979|Clostridiaceae	186801|Clostridia	M	Bacterial sugar transferase	-	-	-	ko:K13012	-	-	-	-	ko00000,ko01005	-	-	-	Bac_transf,Epimerase
KFPFDFKC_03659	526224.Bmur_1782	2.21e-27	109.0	2DPMA@1|root,332MS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03660	742735.HMPREF9467_03385	2.26e-73	243.0	COG3950@1|root,COG3950@2|Bacteria,1V5R6@1239|Firmicutes,24DVP@186801|Clostridia,222SD@1506553|Lachnoclostridium	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
KFPFDFKC_03661	622312.ROSEINA2194_02593	6.14e-308	855.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,247PW@186801|Clostridia	186801|Clostridia	GM	Polysaccharide biosynthesis protein	capD	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
KFPFDFKC_03662	1235802.C823_04890	1.88e-88	274.0	COG5433@1|root,COG5433@2|Bacteria,1V0JK@1239|Firmicutes,249XC@186801|Clostridia	186801|Clostridia	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
KFPFDFKC_03663	1235799.C818_02957	9.64e-74	258.0	COG1368@1|root,COG1368@2|Bacteria,1VI7Z@1239|Firmicutes,24QYG@186801|Clostridia,27PIR@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
KFPFDFKC_03665	622312.ROSEINA2194_03097	0.0	1105.0	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,2492T@186801|Clostridia	186801|Clostridia	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
KFPFDFKC_03666	1235794.C811_00133	1.01e-91	311.0	COG3420@1|root,COG5434@1|root,COG3420@2|Bacteria,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Beta_helix,Big_2,Big_5,DUF3494,Pectate_lyase_3
KFPFDFKC_03667	1235802.C823_02124	2.02e-158	459.0	COG3774@1|root,COG3774@2|Bacteria	2|Bacteria	M	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,NAD_binding_4,PS_pyruv_trans
KFPFDFKC_03668	1235802.C823_02123	2.88e-149	432.0	COG0451@1|root,COG0451@2|Bacteria,1TS59@1239|Firmicutes,247JP@186801|Clostridia,25W52@186806|Eubacteriaceae	186801|Clostridia	GM	NAD dependent epimerase dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
KFPFDFKC_03669	1235802.C823_02122	1.34e-148	422.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,25W5N@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate	-	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,adh_short
KFPFDFKC_03670	478749.BRYFOR_07393	4.89e-119	362.0	COG1134@1|root,COG4641@1|root,COG1134@2|Bacteria,COG4641@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia	186801|Clostridia	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	rfbB	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
KFPFDFKC_03671	411489.CLOL250_00069	1.61e-114	336.0	COG1682@1|root,COG1682@2|Bacteria,1V1J2@1239|Firmicutes,25B57@186801|Clostridia,36WAG@31979|Clostridiaceae	186801|Clostridia	GM	Transport permease protein	-	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
KFPFDFKC_03672	1499684.CCNP01000025_gene3497	4.04e-90	285.0	COG1887@1|root,COG1887@2|Bacteria,1TP75@1239|Firmicutes,24ED0@186801|Clostridia,36FYJ@31979|Clostridiaceae	186801|Clostridia	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	-	-	2.7.8.12	ko:K09809	-	-	-	-	ko00000,ko01000	-	-	-	Glyphos_transf
KFPFDFKC_03673	553973.CLOHYLEM_06254	1.8e-38	143.0	COG3475@1|root,COG3475@2|Bacteria,1VBSV@1239|Firmicutes,24C5H@186801|Clostridia,2246C@1506553|Lachnoclostridium	186801|Clostridia	M	LicD family	licD	-	-	ko:K07271	-	-	-	-	ko00000,ko01000	-	-	-	LicD
KFPFDFKC_03674	1235802.C823_02121	2.1e-227	648.0	COG1887@1|root,COG1887@2|Bacteria,1TSTN@1239|Firmicutes,24AA5@186801|Clostridia,25VZJ@186806|Eubacteriaceae	186801|Clostridia	M	teichoic acid biosynthesis protein B	-	-	2.7.8.14,2.7.8.47	ko:K18704	-	-	R11614,R11621	-	ko00000,ko01000	-	-	-	Glycos_transf_2,Glyphos_transf
KFPFDFKC_03675	1235793.C809_00275	5.66e-66	213.0	COG3385@1|root,COG3385@2|Bacteria,1TY08@1239|Firmicutes,24EQW@186801|Clostridia,27JJD@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
KFPFDFKC_03676	397290.C810_04923	2.89e-81	254.0	COG3385@1|root,COG3385@2|Bacteria,1TY08@1239|Firmicutes,24EQW@186801|Clostridia,27JJD@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
KFPFDFKC_03677	411483.FAEPRAA2165_00991	4.57e-87	267.0	COG1215@1|root,COG1215@2|Bacteria,1V1CB@1239|Firmicutes,24EMU@186801|Clostridia,3WH23@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
KFPFDFKC_03678	397290.C810_03894	2.78e-183	581.0	COG0860@1|root,COG4733@1|root,COG0860@2|Bacteria,COG4733@2|Bacteria,1UZ49@1239|Firmicutes,25F7R@186801|Clostridia,27JMX@186928|unclassified Lachnospiraceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,Big_2,GBS_Bsp-like,Glucosaminidase,RicinB_lectin_2,fn3
KFPFDFKC_03679	397290.C810_03819	7.98e-254	704.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia,27K11@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
KFPFDFKC_03680	397290.C810_03895	1.78e-28	132.0	COG4193@1|root,COG5492@1|root,COG4193@2|Bacteria,COG5492@2|Bacteria,1TRTM@1239|Firmicutes,24C4N@186801|Clostridia,27K3Z@186928|unclassified Lachnospiraceae	186801|Clostridia	G	SH3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Cadherin-like,Dockerin_1,Glucosaminidase,SH3_3
KFPFDFKC_03682	1235800.C819_00199	2.64e-95	293.0	COG0438@1|root,COG0438@2|Bacteria,1V76V@1239|Firmicutes,25IUU@186801|Clostridia,27NJE@186928|unclassified Lachnospiraceae	186801|Clostridia	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03683	552531.BIF_02151	3.47e-137	410.0	COG2244@1|root,COG2244@2|Bacteria,2IA1K@201174|Actinobacteria,4D0KU@85004|Bifidobacteriales	201174|Actinobacteria	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
KFPFDFKC_03684	585394.RHOM_12280	7e-134	389.0	COG1216@1|root,COG1216@2|Bacteria,1VAHM@1239|Firmicutes,24MBF@186801|Clostridia	186801|Clostridia	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
KFPFDFKC_03685	585394.RHOM_12285	1.58e-150	428.0	COG1216@1|root,COG1216@2|Bacteria,1VBWR@1239|Firmicutes,24NB1@186801|Clostridia	186801|Clostridia	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
KFPFDFKC_03686	585394.RHOM_12290	1.72e-152	436.0	COG1216@1|root,COG1216@2|Bacteria,1UD0A@1239|Firmicutes,24GXB@186801|Clostridia	186801|Clostridia	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	GNT-I,Glycos_transf_2
KFPFDFKC_03687	585394.RHOM_12295	5.3e-171	483.0	COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,25EDZ@186801|Clostridia	186801|Clostridia	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
KFPFDFKC_03688	585394.RHOM_12300	1.79e-208	584.0	COG0438@1|root,COG0438@2|Bacteria,1VE1G@1239|Firmicutes	1239|Firmicutes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
KFPFDFKC_03689	585394.RHOM_12305	3.15e-197	554.0	COG0438@1|root,COG0438@2|Bacteria,1UI11@1239|Firmicutes,24CV8@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glycos_transf_1
KFPFDFKC_03690	585394.RHOM_12310	9.01e-226	629.0	COG0438@1|root,COG0438@2|Bacteria,1V0JW@1239|Firmicutes,24CKB@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
KFPFDFKC_03693	585394.RHOM_12330	2.98e-119	355.0	2A542@1|root,30TSQ@2|Bacteria,1V4Q2@1239|Firmicutes,24ISW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03694	585394.RHOM_12335	5.53e-108	332.0	COG0489@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3944@2|Bacteria	2|Bacteria	M	capsule polysaccharide biosynthetic process	wzc	-	2.7.10.1,2.7.10.2	ko:K08252,ko:K08253,ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
KFPFDFKC_03695	585394.RHOM_12340	8.8e-282	777.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,24870@186801|Clostridia	186801|Clostridia	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
KFPFDFKC_03696	1235790.C805_00459	2.19e-103	338.0	COG2242@1|root,COG2242@2|Bacteria,1TPEE@1239|Firmicutes,24D9B@186801|Clostridia,25Y5N@186806|Eubacteriaceae	186801|Clostridia	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
KFPFDFKC_03697	585394.RHOM_12355	4.62e-264	728.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia	186801|Clostridia	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
KFPFDFKC_03698	585394.RHOM_12360	5.28e-136	392.0	COG1682@1|root,COG1682@2|Bacteria,1TQZF@1239|Firmicutes,248R0@186801|Clostridia	186801|Clostridia	GM	Transport permease protein	-	-	-	ko:K09692	ko02010,map02010	M00251	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.104	-	-	ABC2_membrane
KFPFDFKC_03699	585394.RHOM_12365	3.08e-126	360.0	COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,248VX@186801|Clostridia	186801|Clostridia	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02630,iHN637.CLJU_RS02745	dTDP_sugar_isom
KFPFDFKC_03700	585394.RHOM_12370	2.14e-200	556.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,247XE@186801|Clostridia	186801|Clostridia	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
KFPFDFKC_03701	585394.RHOM_12375	7.99e-253	694.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
KFPFDFKC_03702	585394.RHOM_12380	1.23e-140	424.0	2AJ90@1|root,319TX@2|Bacteria,1VFA5@1239|Firmicutes,25DCM@186801|Clostridia	186801|Clostridia	S	Glucosyl transferase GtrII	-	-	-	-	-	-	-	-	-	-	-	-	Glucos_trans_II
KFPFDFKC_03703	585394.RHOM_12385	2.05e-179	503.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,247PG@186801|Clostridia	186801|Clostridia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
KFPFDFKC_03704	585394.RHOM_12390	6.68e-52	164.0	COG1925@1|root,COG1925@2|Bacteria,1VA23@1239|Firmicutes,24N32@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
KFPFDFKC_03705	622312.ROSEINA2194_02611	4.67e-297	813.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
KFPFDFKC_03706	585394.RHOM_12400	1.53e-146	433.0	COG4856@1|root,COG4856@2|Bacteria,1UZEV@1239|Firmicutes,25CGI@186801|Clostridia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
KFPFDFKC_03707	585394.RHOM_12405	1.39e-165	468.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
KFPFDFKC_03708	585394.RHOM_12410	9.98e-164	466.0	28K89@1|root,2Z9W3@2|Bacteria,1V1PZ@1239|Firmicutes,24D2W@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03709	585394.RHOM_12415	1.1e-50	165.0	2DIZ6@1|root,32UC0@2|Bacteria,1VCGW@1239|Firmicutes,24Q40@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03710	585394.RHOM_12420	1.57e-64	199.0	2D61I@1|root,32TKA@2|Bacteria,1VB5H@1239|Firmicutes,24NZW@186801|Clostridia	186801|Clostridia	N	TIGRFAM flagellar operon protein	yvyF	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03711	585394.RHOM_12425	7.09e-77	240.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia	186801|Clostridia	S	ComF family	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
KFPFDFKC_03712	622312.ROSEINA2194_02619	3.41e-177	502.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia	186801|Clostridia	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
KFPFDFKC_03713	585394.RHOM_12435	6.4e-192	536.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia	186801|Clostridia	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
KFPFDFKC_03714	622312.ROSEINA2194_02621	1.41e-172	483.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia	186801|Clostridia	S	Abc transporter	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
KFPFDFKC_03715	585394.RHOM_12445	0.0	1270.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
KFPFDFKC_03716	622312.ROSEINA2194_03005	1.33e-36	127.0	COG3951@1|root,COG3951@2|Bacteria,1VICK@1239|Firmicutes,24QXM@186801|Clostridia	186801|Clostridia	MNO	Flagellar rod assembly protein muramidase FlgJ	-	-	-	-	-	-	-	-	-	-	-	-	Rod-binding
KFPFDFKC_03717	585394.RHOM_12455	9.08e-139	398.0	COG4786@1|root,COG4786@2|Bacteria,1TT5Z@1239|Firmicutes,248M9@186801|Clostridia	186801|Clostridia	N	basal body rod protein	flgG	-	-	ko:K02390,ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
KFPFDFKC_03718	585394.RHOM_12460	8.36e-152	431.0	COG4786@1|root,COG4786@2|Bacteria,1TRFQ@1239|Firmicutes,24C2V@186801|Clostridia	186801|Clostridia	N	basal body rod protein	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
KFPFDFKC_03719	585394.RHOM_12465	7e-221	611.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia	186801|Clostridia	D	Cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
KFPFDFKC_03720	585394.RHOM_12045	4.34e-63	211.0	COG3274@1|root,COG3274@2|Bacteria	2|Bacteria	S	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
KFPFDFKC_03721	585394.RHOM_12025	1.62e-72	235.0	COG3594@1|root,COG3594@2|Bacteria,1VJ6T@1239|Firmicutes,24UK1@186801|Clostridia	186801|Clostridia	G	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
KFPFDFKC_03722	1123248.KB893314_gene3360	8.33e-62	202.0	COG0438@1|root,COG0438@2|Bacteria,4PN7G@976|Bacteroidetes,1J005@117747|Sphingobacteriia	976|Bacteroidetes	M	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
KFPFDFKC_03723	1469948.JPNB01000002_gene3304	9.14e-22	88.2	COG1396@1|root,COG1396@2|Bacteria,1VAEQ@1239|Firmicutes,24RMB@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
KFPFDFKC_03724	585394.RHOM_12475	0.0	1770.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
KFPFDFKC_03725	585394.RHOM_12480	0.0	1221.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
KFPFDFKC_03726	585394.RHOM_12610	2.33e-252	696.0	COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia	186801|Clostridia	C	domain protein	norV	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Flavodoxin_5,Lactamase_B,Lactamase_B_2
KFPFDFKC_03727	585394.RHOM_12615	0.0	1536.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
KFPFDFKC_03728	585394.RHOM_12620	2.17e-52	165.0	2E3FD@1|root,32YE7@2|Bacteria,1VEE4@1239|Firmicutes,24QJ7@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TSCPD
KFPFDFKC_03729	585394.RHOM_12625	6.39e-124	354.0	COG0452@1|root,COG0452@2|Bacteria,1TQPT@1239|Firmicutes,24HE6@186801|Clostridia	186801|Clostridia	H	Dipicolinic acid synthetase, b subunit	spoVFB	-	-	ko:K06411	-	-	-	-	ko00000	-	-	-	Flavoprotein
KFPFDFKC_03730	585394.RHOM_12630	2.51e-144	413.0	COG0169@1|root,COG0169@2|Bacteria,1UHR5@1239|Firmicutes,25ETW@186801|Clostridia	186801|Clostridia	E	dipicolinic acid synthetase, A subunit	-	-	-	ko:K06410	-	-	-	-	ko00000	-	-	-	2-Hacid_dh_C,AdoHcyase_NAD,DpaA_N,IlvN
KFPFDFKC_03731	622312.ROSEINA2194_03033	3.55e-296	810.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia	186801|Clostridia	E	Belongs to the aspartokinase family	thrA	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
KFPFDFKC_03732	585394.RHOM_12645	4.36e-136	391.0	COG2908@1|root,COG2908@2|Bacteria,1TT6N@1239|Firmicutes,24A8X@186801|Clostridia	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
KFPFDFKC_03733	585394.RHOM_12650	7.89e-92	282.0	2C69W@1|root,2Z7HR@2|Bacteria,1TQNN@1239|Firmicutes,249G5@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4474)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4474
KFPFDFKC_03734	411470.RUMGNA_01046	2.54e-301	832.0	COG0246@1|root,COG0246@2|Bacteria,1TQ97@1239|Firmicutes,247TG@186801|Clostridia,3XYQY@572511|Blautia	186801|Clostridia	G	Mannitol dehydrogenase Rossmann domain	-	-	1.1.1.57	ko:K00040	ko00040,ko01100,map00040,map01100	M00061	R02454	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
KFPFDFKC_03735	658655.HMPREF0988_01291	3.86e-130	378.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1TPMG@1239|Firmicutes,25E9N@186801|Clostridia,27UHQ@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	ARD,AraC_binding,Cupin_2,HTH_18
KFPFDFKC_03736	658088.HMPREF0987_02461	1.17e-167	472.0	COG1402@1|root,COG1402@2|Bacteria,1UDUM@1239|Firmicutes,2494R@186801|Clostridia	186801|Clostridia	S	Creatinine amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Creatininase
KFPFDFKC_03737	658088.HMPREF0987_02460	7.06e-128	372.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
KFPFDFKC_03738	658088.HMPREF0987_02459	1.5e-266	737.0	COG2211@1|root,COG2211@2|Bacteria,1TRYR@1239|Firmicutes,25C8G@186801|Clostridia,27KBK@186928|unclassified Lachnospiraceae	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
KFPFDFKC_03739	658088.HMPREF0987_02458	3.05e-108	325.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1TPMG@1239|Firmicutes,24ISI@186801|Clostridia,27T9S@186928|unclassified Lachnospiraceae	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
KFPFDFKC_03740	877415.JNJQ01000002_gene2280	1.31e-231	640.0	COG1312@1|root,COG1312@2|Bacteria,1TP5F@1239|Firmicutes,3VPNW@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Catalyzes the dehydration of D-mannonate	uxuA	-	-	-	-	-	-	-	-	-	-	-	UxuA
KFPFDFKC_03741	585394.RHOM_12655	2.1e-108	323.0	COG1388@1|root,COG1388@2|Bacteria,1V4FC@1239|Firmicutes	1239|Firmicutes	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	LysM
KFPFDFKC_03742	585394.RHOM_12660	3.95e-124	358.0	COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes,24AGM@186801|Clostridia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	lrgB	-	-	-	-	-	-	-	-	-	-	-	LrgB
KFPFDFKC_03743	585394.RHOM_12665	4.74e-51	164.0	COG1380@1|root,COG1380@2|Bacteria,1VEN4@1239|Firmicutes,24MMB@186801|Clostridia	186801|Clostridia	S	LrgA family	lrgA	-	-	ko:K06518	-	-	-	-	ko00000,ko02000	1.E.14.2	-	-	LrgA
KFPFDFKC_03744	622312.ROSEINA2194_03041	3.55e-191	546.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1TR1R@1239|Firmicutes,24A67@186801|Clostridia	186801|Clostridia	CE	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
KFPFDFKC_03745	585394.RHOM_12675	6.15e-85	258.0	COG0727@1|root,COG0727@2|Bacteria,1TT6P@1239|Firmicutes,24BWS@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
KFPFDFKC_03746	1235800.C819_03424	2.79e-173	495.0	COG0657@1|root,COG0657@2|Bacteria,1VUQV@1239|Firmicutes,250IT@186801|Clostridia,27UKJ@186928|unclassified Lachnospiraceae	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
KFPFDFKC_03747	1226325.HMPREF1548_02199	2.55e-25	97.4	COG4942@1|root,COG4942@2|Bacteria,1VSWX@1239|Firmicutes	1239|Firmicutes	D	K03657 DNA helicase II ATP-dependent DNA helicase PcrA	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03748	658086.HMPREF0994_01172	3.3e-19	84.7	COG4942@1|root,COG4942@2|Bacteria,1V67C@1239|Firmicutes,25FCI@186801|Clostridia	186801|Clostridia	D	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
KFPFDFKC_03749	622312.ROSEINA2194_03055	1.63e-151	434.0	COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,247WV@186801|Clostridia	186801|Clostridia	P	Belongs to the nlpA lipoprotein family	metQ	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
KFPFDFKC_03750	585394.RHOM_12805	9.38e-129	369.0	COG2011@1|root,COG2011@2|Bacteria,1TRSY@1239|Firmicutes,24AZ9@186801|Clostridia	186801|Clostridia	P	ABC-type metal ion transport system permease component	metI	-	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
KFPFDFKC_03751	622312.ROSEINA2194_03057	9.3e-180	508.0	COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,248PZ@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
KFPFDFKC_03753	622312.ROSEINA2194_03059	9.87e-190	530.0	COG0583@1|root,COG0583@2|Bacteria,1TP3E@1239|Firmicutes,248HI@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
KFPFDFKC_03754	585394.RHOM_12825	3.39e-149	426.0	COG1284@1|root,COG1284@2|Bacteria,1TRAU@1239|Firmicutes,249DE@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
KFPFDFKC_03755	622312.ROSEINA2194_00531	9.66e-68	209.0	2E06E@1|root,32VUE@2|Bacteria,1VCMY@1239|Firmicutes,24NKQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03758	1504823.CCMM01000008_gene907	1.81e-153	439.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	yeiI	-	2.7.1.15,2.7.1.45,2.7.1.83	ko:K00852,ko:K00874,ko:K16328	ko00030,ko00240,ko01100,ko01120,ko01200,map00030,map00240,map01100,map01120,map01200	M00061,M00308,M00631	R01051,R01541,R02750,R03315	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_24,PfkB
KFPFDFKC_03759	411489.CLOL250_01422	6.32e-05	43.5	2EMZ1@1|root,33FM6@2|Bacteria,1VMDZ@1239|Firmicutes,24X8Z@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03760	411489.CLOL250_01423	3.4e-235	652.0	COG0786@1|root,COG0786@2|Bacteria,1TQA4@1239|Firmicutes,247WX@186801|Clostridia,36EF4@31979|Clostridiaceae	186801|Clostridia	P	Catalyzes the sodium-dependent transport of glutamate	gltS	-	-	ko:K03312	-	-	-	-	ko00000,ko02000	2.A.27	-	-	Glt_symporter,NMT1_3
KFPFDFKC_03761	411489.CLOL250_01424	2.48e-122	360.0	COG2358@1|root,COG2358@2|Bacteria,1TPXW@1239|Firmicutes,2489U@186801|Clostridia,36I0C@31979|Clostridiaceae	186801|Clostridia	S	TRAP transporter solute receptor, TAXI family	bcsP	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
KFPFDFKC_03762	585394.RHOM_12905	2.52e-316	866.0	COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,248K3@186801|Clostridia	186801|Clostridia	E	Dipeptidase	pepD	-	-	ko:K08659	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C69
KFPFDFKC_03763	140626.JHWB01000022_gene2128	2.64e-81	248.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24J27@186801|Clostridia	186801|Clostridia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
KFPFDFKC_03764	622312.ROSEINA2194_00248	3.95e-262	725.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
KFPFDFKC_03765	622312.ROSEINA2194_00247	1.59e-227	634.0	COG4286@1|root,COG4286@2|Bacteria,1V2PW@1239|Firmicutes,248SR@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	UPF0160
KFPFDFKC_03766	1487921.DP68_07245	1.58e-47	177.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,36EG9@31979|Clostridiaceae	186801|Clostridia	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
KFPFDFKC_03767	1031288.AXAA01000010_gene454	1.2e-07	57.8	COG0840@1|root,COG0840@2|Bacteria,1URS2@1239|Firmicutes,24B7E@186801|Clostridia,36H9N@31979|Clostridiaceae	186801|Clostridia	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
KFPFDFKC_03768	1280698.AUJS01000065_gene671	8.1e-178	510.0	COG4924@1|root,COG4924@2|Bacteria,1TRVG@1239|Firmicutes,24D0P@186801|Clostridia	186801|Clostridia	S	Protein of unknown function N-terminus (DUF3323)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2399,DUF3323
KFPFDFKC_03769	1280698.AUJS01000065_gene670	0.0	1653.0	COG1196@1|root,COG1196@2|Bacteria,1TPW9@1239|Firmicutes,247V7@186801|Clostridia	186801|Clostridia	D	Putative exonuclease SbcCD, C subunit	-	-	-	-	-	-	-	-	-	-	-	-	SbcCD_C
KFPFDFKC_03770	1280698.AUJS01000065_gene669	9.33e-219	610.0	28HUD@1|root,2Z813@2|Bacteria,1TUFV@1239|Firmicutes,24A4P@186801|Clostridia	186801|Clostridia	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2398
KFPFDFKC_03771	1280698.AUJS01000065_gene668	1.31e-287	795.0	2CC51@1|root,2Z7IU@2|Bacteria,1TQNI@1239|Firmicutes,24DDD@186801|Clostridia	186801|Clostridia	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2397
KFPFDFKC_03772	1519439.JPJG01000004_gene1042	4.9e-17	76.6	COG1595@1|root,COG1595@2|Bacteria,1V9ZH@1239|Firmicutes,24HPJ@186801|Clostridia,2N8XY@216572|Oscillospiraceae	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
KFPFDFKC_03773	1519439.JPJG01000004_gene1043	2.67e-62	199.0	28PC7@1|root,2ZC4N@2|Bacteria,1VDMU@1239|Firmicutes,24J12@186801|Clostridia,2N8HS@216572|Oscillospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03774	1216932.CM240_0224	4.99e-52	184.0	COG1305@1|root,COG1305@2|Bacteria,1UVFG@1239|Firmicutes,2496A@186801|Clostridia	186801|Clostridia	E	Participates in initiation and elongation during chromosome replication	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,Transglut_core
KFPFDFKC_03775	622312.ROSEINA2194_01381	1.51e-78	238.0	2C9EF@1|root,32RP7@2|Bacteria,1V15W@1239|Firmicutes,24GXC@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF1911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1910,DUF1911
KFPFDFKC_03776	1121929.KB898687_gene65	6.53e-18	82.8	28NWS@1|root,30KF3@2|Bacteria,1U600@1239|Firmicutes,4ID4G@91061|Bacilli,471XI@74385|Gracilibacillus	91061|Bacilli	S	SMI1 / KNR4 family (SUKH-1)	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03777	622312.ROSEINA2194_03927	3.48e-31	128.0	COG3501@1|root,COG3501@2|Bacteria,1V3I5@1239|Firmicutes,24GKG@186801|Clostridia	186801|Clostridia	F	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
KFPFDFKC_03779	585394.RHOM_00655	2.4e-70	213.0	COG1516@1|root,COG1516@2|Bacteria,1VA8K@1239|Firmicutes,24MRW@186801|Clostridia	186801|Clostridia	N	flagellar protein flis	fliS	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
KFPFDFKC_03780	585394.RHOM_00660	2.92e-73	223.0	2CW8V@1|root,32SZ6@2|Bacteria,1VAWT@1239|Firmicutes,24N6N@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FlgN
KFPFDFKC_03781	742765.HMPREF9457_03768	6.41e-151	428.0	COG1484@1|root,COG1484@2|Bacteria,1TQBX@1239|Firmicutes,249T2@186801|Clostridia,27WZ8@189330|Dorea	186801|Clostridia	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
KFPFDFKC_03782	1235793.C809_00385	3.87e-190	536.0	COG3385@1|root,COG3385@2|Bacteria,1UTR4@1239|Firmicutes,24CFF@186801|Clostridia,27J6S@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
KFPFDFKC_03783	1226325.HMPREF1548_02751	3.68e-74	238.0	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
KFPFDFKC_03784	742765.HMPREF9457_03807	9.02e-136	387.0	COG4584@1|root,COG4584@2|Bacteria,1TUCZ@1239|Firmicutes,25NK9@186801|Clostridia,27WZW@189330|Dorea	186801|Clostridia	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03785	1410628.JNKS01000009_gene3138	1.15e-69	225.0	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia,27MRG@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
KFPFDFKC_03786	1226325.HMPREF1548_02751	3.27e-62	209.0	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
KFPFDFKC_03787	622312.ROSEINA2194_03516	8.33e-250	694.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
KFPFDFKC_03788	622312.ROSEINA2194_04368	3.57e-79	236.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01195	ATP-synt_DE,ATP-synt_DE_N
KFPFDFKC_03789	622312.ROSEINA2194_04367	0.0	866.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
KFPFDFKC_03790	585394.RHOM_16030	1.41e-159	452.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
KFPFDFKC_03791	622312.ROSEINA2194_04365	0.0	926.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
KFPFDFKC_03792	622312.ROSEINA2194_04364	5.73e-101	296.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,24MSA@186801|Clostridia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
KFPFDFKC_03793	585394.RHOM_16045	4.29e-44	150.0	COG0711@1|root,COG0711@2|Bacteria,1V74H@1239|Firmicutes,25CRV@186801|Clostridia	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
KFPFDFKC_03794	1235802.C823_01323	1.62e-44	145.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,25XKI@186806|Eubacteriaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
KFPFDFKC_03795	585394.RHOM_16055	8.22e-154	435.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6Q@186801|Clostridia	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
KFPFDFKC_03796	622312.ROSEINA2194_04360	1.34e-68	210.0	2CFN0@1|root,32RUQ@2|Bacteria,1VD5D@1239|Firmicutes,24MN1@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_I
KFPFDFKC_03797	622312.ROSEINA2194_04359	9.24e-33	115.0	2EC2U@1|root,3361T@2|Bacteria,1VK1M@1239|Firmicutes,24RW0@186801|Clostridia	186801|Clostridia	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
KFPFDFKC_03798	585394.RHOM_16075	1.87e-102	297.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia	186801|Clostridia	F	cytidine and deoxycytidylate deaminase zinc-binding region	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
KFPFDFKC_03799	585394.RHOM_16080	1.24e-144	408.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,248FV@186801|Clostridia	186801|Clostridia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
KFPFDFKC_03800	622312.ROSEINA2194_04355	1.12e-79	240.0	COG0394@1|root,COG0394@2|Bacteria,1UIG5@1239|Firmicutes,25EMJ@186801|Clostridia	186801|Clostridia	T	Low molecular weight phosphotyrosine protein phosphatase	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
KFPFDFKC_03801	622312.ROSEINA2194_04354	6.31e-210	585.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
KFPFDFKC_03802	585394.RHOM_16095	8.55e-213	592.0	COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,249DZ@186801|Clostridia	186801|Clostridia	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
KFPFDFKC_03803	585394.RHOM_16100	3.41e-18	76.6	COG2768@1|root,COG2768@2|Bacteria,1VET2@1239|Firmicutes,24QUH@186801|Clostridia	186801|Clostridia	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
KFPFDFKC_03804	622312.ROSEINA2194_00870	3.36e-305	834.0	COG1373@1|root,COG1373@2|Bacteria,1TQ8Z@1239|Firmicutes,2499K@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
KFPFDFKC_03805	742722.HMPREF9463_01777	7.35e-19	81.3	COG1669@1|root,COG1669@2|Bacteria,2HVIG@201174|Actinobacteria,4CWW6@84998|Coriobacteriia	84998|Coriobacteriia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
KFPFDFKC_03807	585394.RHOM_16105	4.21e-79	244.0	COG0789@1|root,COG0789@2|Bacteria,1V4F1@1239|Firmicutes,24NFY@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, MerR family	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
KFPFDFKC_03808	585394.RHOM_16615	4.91e-301	823.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
KFPFDFKC_03809	585394.RHOM_16620	1.11e-87	259.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia	186801|Clostridia	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
KFPFDFKC_03810	585394.RHOM_16625	0.0	1115.0	COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,2484R@186801|Clostridia	186801|Clostridia	T	domain protein	yybT	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
KFPFDFKC_03811	622312.ROSEINA2194_04348	1.72e-38	140.0	COG3187@1|root,COG3187@2|Bacteria,1UMA9@1239|Firmicutes,25GDD@186801|Clostridia	186801|Clostridia	O	Heat shock protein	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03812	1235793.C809_00094	9.24e-172	486.0	COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,247M1@186801|Clostridia,27IAP@186928|unclassified Lachnospiraceae	186801|Clostridia	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
KFPFDFKC_03813	742735.HMPREF9467_00252	0.0	908.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia,21Z5X@1506553|Lachnoclostridium	186801|Clostridia	G	Glycosyl hydrolase family 36 C-terminal domain	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
KFPFDFKC_03814	1298920.KI911353_gene656	3.01e-276	770.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,21XQ0@1506553|Lachnoclostridium	186801|Clostridia	G	SMART alpha amylase catalytic sub domain	malL	-	3.2.1.1,3.2.1.10	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
KFPFDFKC_03815	1449050.JNLE01000003_gene575	2.05e-172	488.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,36F5I@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator, LacI family	-	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
KFPFDFKC_03816	1235793.C809_00086	1.98e-161	477.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia,27J9G@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolases family 32	-	-	3.2.1.80	ko:K03332	ko00051,map00051	-	R00879	-	ko00000,ko00001,ko01000	-	-	-	Big_2,CW_binding_1,Cadherin-like,DUF1080,Flg_new,Glyco_hydro_32C,Glyco_hydro_32N
KFPFDFKC_03817	1226325.HMPREF1548_04993	3.67e-298	820.0	COG0366@1|root,COG0366@2|Bacteria,1TR93@1239|Firmicutes,24AB0@186801|Clostridia,36FBK@31979|Clostridiaceae	186801|Clostridia	G	Sucrose phosphorylase	-	GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016758	2.4.1.329,2.4.1.7	ko:K00690,ko:K21350	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
KFPFDFKC_03818	1449050.JNLE01000003_gene571	6.72e-151	430.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia,36EZR@31979|Clostridiaceae	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
KFPFDFKC_03819	1449050.JNLE01000003_gene570	1.41e-176	496.0	COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,24ADV@186801|Clostridia,36DX1@31979|Clostridiaceae	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
KFPFDFKC_03820	1449050.JNLE01000003_gene569	1.58e-228	641.0	COG2182@1|root,COG2182@2|Bacteria,1UIC9@1239|Firmicutes,2499Z@186801|Clostridia,36UQF@31979|Clostridiaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
KFPFDFKC_03821	397291.C804_04832	1.56e-266	825.0	COG3209@1|root,COG3693@1|root,COG5492@1|root,COG3209@2|Bacteria,COG3693@2|Bacteria,COG5492@2|Bacteria,1UHTC@1239|Firmicutes,248KD@186801|Clostridia,27K6N@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Carbohydrate family 9 binding domain-like	-	-	3.2.1.4,3.2.1.8	ko:K01179,ko:K01181	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM9_1,CBM_4_9,Glyco_hydro_10,Polysacc_deac_1,SLH
KFPFDFKC_03822	180332.JTGN01000009_gene4214	2.05e-43	162.0	COG3533@1|root,COG5492@1|root,COG3533@2|Bacteria,COG5492@2|Bacteria,1VTDU@1239|Firmicutes	1239|Firmicutes	N	Bacterial Ig-like domain (group 4)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2,Big_4
KFPFDFKC_03823	585394.RHOM_16635	1.51e-57	178.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia	186801|Clostridia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
KFPFDFKC_03824	585394.RHOM_16640	8.85e-97	282.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia	186801|Clostridia	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
KFPFDFKC_03825	585394.RHOM_16645	4.62e-54	170.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
KFPFDFKC_03826	622312.ROSEINA2194_04343	1.32e-33	116.0	COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,24QKA@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
KFPFDFKC_03827	556261.HMPREF0240_03996	1.75e-80	241.0	COG4894@1|root,COG4894@2|Bacteria,1V3WA@1239|Firmicutes,24MB0@186801|Clostridia,36KCK@31979|Clostridiaceae	186801|Clostridia	S	LURP-one-related	-	-	-	-	-	-	-	-	-	-	-	-	LOR
KFPFDFKC_03828	585394.RHOM_16655	1.52e-156	441.0	COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,2491J@186801|Clostridia	186801|Clostridia	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
KFPFDFKC_03829	483218.BACPEC_02910	7.56e-149	447.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,268D0@186813|unclassified Clostridiales	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
KFPFDFKC_03831	585394.RHOM_16660	2.33e-84	253.0	COG0700@1|root,COG0700@2|Bacteria,1V45M@1239|Firmicutes,24HSJ@186801|Clostridia	186801|Clostridia	S	PFAM nucleoside recognition domain protein	spmB	-	-	ko:K06374	-	-	-	-	ko00000	-	-	-	Gate
KFPFDFKC_03832	622312.ROSEINA2194_04339	7.24e-231	654.0	COG2199@1|root,COG2200@1|root,COG2200@2|Bacteria,COG3706@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,Response_reg
KFPFDFKC_03833	585394.RHOM_16670	4.05e-104	305.0	COG2715@1|root,COG2715@2|Bacteria,1V1E2@1239|Firmicutes,249G0@186801|Clostridia	186801|Clostridia	S	membrane protein required for spore maturation	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
KFPFDFKC_03834	585394.RHOM_16680	3.85e-235	669.0	COG4805@1|root,COG4805@2|Bacteria,1TREN@1239|Firmicutes,249U9@186801|Clostridia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
KFPFDFKC_03835	622312.ROSEINA2194_04330	9.73e-173	485.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia	186801|Clostridia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
KFPFDFKC_03836	642492.Clole_0437	3.32e-153	435.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport system ATPase component	-	-	-	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	M00188,M00436	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.2	-	-	ABC_tran
KFPFDFKC_03837	642492.Clole_0436	7.61e-134	385.0	COG0600@1|root,COG0600@2|Bacteria,1UYCY@1239|Firmicutes,249RH@186801|Clostridia	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050,ko:K15552	ko00920,ko02010,map00920,map02010	M00188,M00435	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4	-	-	BPD_transp_1
KFPFDFKC_03838	642492.Clole_0435	1.15e-166	476.0	COG0715@1|root,COG0715@2|Bacteria,1UYBA@1239|Firmicutes,24D4Q@186801|Clostridia	186801|Clostridia	P	TIGRFAM ABC transporter, substrate-binding protein, aliphatic	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,OmpA
KFPFDFKC_03839	642492.Clole_0434	3.99e-54	171.0	COG0347@1|root,COG0347@2|Bacteria,1V73J@1239|Firmicutes,24S5C@186801|Clostridia	186801|Clostridia	K	Belongs to the P(II) protein family	-	-	-	ko:K02590	-	-	-	-	ko00000	-	-	-	P-II
KFPFDFKC_03840	642492.Clole_0433	3.29e-49	159.0	COG0347@1|root,COG0347@2|Bacteria,1VASB@1239|Firmicutes,24J84@186801|Clostridia	186801|Clostridia	K	Belongs to the P(II) protein family	-	-	-	ko:K02589	-	-	-	-	ko00000	-	-	-	P-II
KFPFDFKC_03841	642492.Clole_0432	2.1e-282	786.0	COG0154@1|root,COG0154@2|Bacteria,1TSAQ@1239|Firmicutes,2483V@186801|Clostridia	186801|Clostridia	J	PFAM Amidase	-	-	3.5.1.54	ko:K01457	ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120	-	R00005	RC02756	ko00000,ko00001,ko01000	-	-	-	Amidase
KFPFDFKC_03842	642492.Clole_0431	0.0	1906.0	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,1TPUN@1239|Firmicutes,24E9Y@186801|Clostridia	186801|Clostridia	EI	Allophanate hydrolase subunit 1	-	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
KFPFDFKC_03843	642492.Clole_0430	2.36e-137	390.0	COG3665@1|root,COG3665@2|Bacteria,1UYE1@1239|Firmicutes,24DNP@186801|Clostridia	186801|Clostridia	S	TIGRFAM Urea carboxylase-associated protein 1	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
KFPFDFKC_03844	642492.Clole_0429	1.12e-155	438.0	COG3665@1|root,COG3665@2|Bacteria,1TQQF@1239|Firmicutes,24DHT@186801|Clostridia	186801|Clostridia	S	TIGRFAM Urea carboxylase-associated protein 2	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
KFPFDFKC_03845	642492.Clole_0428	1.6e-79	247.0	COG2197@1|root,COG2197@2|Bacteria,1V7ZQ@1239|Firmicutes,25BMW@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
KFPFDFKC_03846	868595.Desca_1045	2.92e-71	231.0	COG0715@1|root,COG0715@2|Bacteria,1UYBA@1239|Firmicutes,24D4Q@186801|Clostridia	186801|Clostridia	P	TIGRFAM ABC transporter, substrate-binding protein, aliphatic	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,OmpA
KFPFDFKC_03847	868595.Desca_1046	1.02e-55	181.0	COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,24A9U@186801|Clostridia	186801|Clostridia	Q	PFAM Isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
KFPFDFKC_03848	1121342.AUCO01000013_gene1770	9.04e-46	160.0	COG2197@1|root,COG2197@2|Bacteria,1V7ZQ@1239|Firmicutes,25BMW@186801|Clostridia,36WKG@31979|Clostridiaceae	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
KFPFDFKC_03849	622312.ROSEINA2194_00855	9.51e-23	88.2	2EJZ9@1|root,33DPV@2|Bacteria,1VQST@1239|Firmicutes,254M5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03850	397290.C810_01918	1.64e-109	329.0	COG5492@1|root,COG5492@2|Bacteria,1V4A5@1239|Firmicutes,24IM0@186801|Clostridia,27MBH@186928|unclassified Lachnospiraceae	186801|Clostridia	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
KFPFDFKC_03851	1414720.CBYM010000015_gene2999	2.56e-119	348.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,36DPF@31979|Clostridiaceae	186801|Clostridia	HP	ABC transporter	fhuC	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
KFPFDFKC_03852	1414720.CBYM010000015_gene3000	3.52e-137	399.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,24BGM@186801|Clostridia,36EF1@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	fhuG	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
KFPFDFKC_03853	1414720.CBYM010000015_gene3001	2.12e-138	402.0	COG0609@1|root,COG0609@2|Bacteria,1TP13@1239|Firmicutes,24A8W@186801|Clostridia,36FH9@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	fhuB	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
KFPFDFKC_03854	1499683.CCFF01000013_gene228	7.71e-159	454.0	COG0614@1|root,COG0614@2|Bacteria,1TQMK@1239|Firmicutes,24B1M@186801|Clostridia,36EU7@31979|Clostridiaceae	186801|Clostridia	P	Periplasmic binding protein	fhuD	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
KFPFDFKC_03855	290402.Cbei_2136	7.38e-90	280.0	COG2207@1|root,COG2207@2|Bacteria,1V0EE@1239|Firmicutes,25B24@186801|Clostridia,36FJY@31979|Clostridiaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
KFPFDFKC_03856	585394.RHOM_16690	3.76e-144	410.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24BK7@186801|Clostridia	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
KFPFDFKC_03857	622312.ROSEINA2194_04328	1.02e-153	434.0	COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,249UH@186801|Clostridia	186801|Clostridia	S	Methyltransferase	yfiC	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS,Methyltransf_31
KFPFDFKC_03858	622312.ROSEINA2194_04327	2.14e-187	524.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,247Q6@186801|Clostridia	186801|Clostridia	K	domain protein	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
KFPFDFKC_03859	622312.ROSEINA2194_04326	8.13e-199	556.0	COG2812@1|root,COG2812@2|Bacteria,1VCQC@1239|Firmicutes,248U4@186801|Clostridia	186801|Clostridia	L	'dna polymerase iii	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
KFPFDFKC_03860	622312.ROSEINA2194_04325	4.89e-82	244.0	COG1728@1|root,COG1728@2|Bacteria,1VF6M@1239|Firmicutes,24S6C@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF327)	-	-	-	ko:K09770	-	-	-	-	ko00000	-	-	-	DUF327
KFPFDFKC_03861	622312.ROSEINA2194_04324	1.47e-96	286.0	COG0194@1|root,COG0194@2|Bacteria,1V3RZ@1239|Firmicutes,24HKC@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	gmk_1	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
KFPFDFKC_03862	622312.ROSEINA2194_04323	2.6e-206	588.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia	186801|Clostridia	E	Orn Lys Arg decarboxylase major	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
KFPFDFKC_03863	622312.ROSEINA2194_04322	2.62e-96	293.0	COG0746@1|root,COG0746@2|Bacteria	2|Bacteria	H	molybdenum cofactor guanylyltransferase activity	mobA	GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.77	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	DUF3305,NTP_transf_3
KFPFDFKC_03864	585394.RHOM_16730	1.8e-72	232.0	2EE0F@1|root,337V8@2|Bacteria,1VFWV@1239|Firmicutes,24SC3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03865	585394.RHOM_16735	2.65e-112	327.0	COG5340@1|root,COG5340@2|Bacteria,1USGA@1239|Firmicutes,24IEV@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, AbiEi antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
KFPFDFKC_03866	585394.RHOM_16745	4.46e-208	590.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
KFPFDFKC_03867	622312.ROSEINA2194_04317	3.25e-137	389.0	COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,248YR@186801|Clostridia	186801|Clostridia	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
KFPFDFKC_03869	622312.ROSEINA2194_04314	3.77e-235	653.0	COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,248JJ@186801|Clostridia	186801|Clostridia	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M42
KFPFDFKC_03870	585394.RHOM_16765	7.28e-16	89.4	COG5386@1|root,COG5386@2|Bacteria,1V541@1239|Firmicutes	1239|Firmicutes	M	Cell surface protein	surfB1	-	-	-	-	-	-	-	-	-	-	-	NEAT,SLH
KFPFDFKC_03871	585394.RHOM_16785	1.02e-275	760.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	mepA_2	-	-	-	-	-	-	-	-	-	-	-	MatE
KFPFDFKC_03872	1232453.BAIF02000044_gene3509	3.61e-18	80.5	28NU7@1|root,2ZBSM@2|Bacteria,1V2N8@1239|Firmicutes,24G4F@186801|Clostridia,26BKZ@186813|unclassified Clostridiales	186801|Clostridia	S	NOG32933 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03873	585394.RHOM_13430	2.33e-142	404.0	2DB6M@1|root,2Z7HS@2|Bacteria,1U8V8@1239|Firmicutes,249IN@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2871
KFPFDFKC_03874	483218.BACPEC_02760	3.58e-80	240.0	COG1846@1|root,COG1846@2|Bacteria,1V3G1@1239|Firmicutes,24G8T@186801|Clostridia,26CGS@186813|unclassified Clostridiales	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
KFPFDFKC_03875	483218.BACPEC_02215	2.33e-149	420.0	COG1838@1|root,COG1838@2|Bacteria,1TSJ8@1239|Firmicutes,25CDD@186801|Clostridia,269T7@186813|unclassified Clostridiales	186801|Clostridia	C	Fumarase C-terminus	ttdB	-	4.2.1.2,4.2.1.32	ko:K01678,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
KFPFDFKC_03876	483218.BACPEC_02216	1.07e-219	606.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,2685W@186813|unclassified Clostridiales	186801|Clostridia	C	Fumarate hydratase (Fumerase)	-	-	4.2.1.32	ko:K03779	ko00630,map00630	-	R00339	RC01382	ko00000,ko00001,ko01000	-	-	-	Fumerase
KFPFDFKC_03877	483218.BACPEC_02217	3.02e-277	762.0	COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,24D6M@186801|Clostridia,26A6P@186813|unclassified Clostridiales	186801|Clostridia	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp
KFPFDFKC_03878	483218.BACPEC_02218	1.89e-136	390.0	COG0583@1|root,COG0583@2|Bacteria,1TQ6Y@1239|Firmicutes,25C6V@186801|Clostridia	186801|Clostridia	K	lysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
KFPFDFKC_03879	622312.ROSEINA2194_04272	1.01e-308	843.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
KFPFDFKC_03880	622312.ROSEINA2194_04268	0.0	1161.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Alpha-amylase_N,Malt_amylase_C
KFPFDFKC_03881	483218.BACPEC_03095	2e-115	331.0	COG0716@1|root,COG0716@2|Bacteria,1VB6B@1239|Firmicutes,24GQN@186801|Clostridia,269I5@186813|unclassified Clostridiales	186801|Clostridia	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_3
KFPFDFKC_03882	585394.RHOM_01350	0.0	1113.0	COG2200@1|root,COG2200@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9
KFPFDFKC_03883	483218.BACPEC_03093	0.0	884.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,26B8C@186813|unclassified Clostridiales	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
KFPFDFKC_03884	397288.C806_00504	3.95e-45	153.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia,27KKZ@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
KFPFDFKC_03885	511680.BUTYVIB_00660	1.46e-19	90.1	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,4BYKX@830|Butyrivibrio	186801|Clostridia	L	Bacterial DNA topoisomeraes I ATP-binding domain	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
KFPFDFKC_03886	622312.ROSEINA2194_01137	4.52e-244	685.0	COG0577@1|root,COG0577@2|Bacteria,1V15I@1239|Firmicutes,24DNT@186801|Clostridia	2|Bacteria	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
KFPFDFKC_03887	622312.ROSEINA2194_01139	5.25e-103	302.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
KFPFDFKC_03888	622312.ROSEINA2194_03260	5.68e-126	360.0	COG5340@1|root,COG5340@2|Bacteria,1TQSK@1239|Firmicutes,247JC@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
KFPFDFKC_03889	1123263.AUKY01000003_gene293	4.78e-108	330.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,3VP6Z@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	-	-	-	-	-	-	-	-	-	-	-	-	Topoisom_bac,Toprim
KFPFDFKC_03890	1123263.AUKY01000003_gene294	4.71e-296	810.0	COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,3VQ6U@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
KFPFDFKC_03891	1123263.AUKY01000003_gene295	9.79e-26	101.0	28HUZ@1|root,2Z81G@2|Bacteria,1TS04@1239|Firmicutes,3VRWU@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Domain of unknown function (DUF4366)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4366
KFPFDFKC_03892	1410626.JHXB01000018_gene1524	6.94e-34	117.0	COG1396@1|root,COG1396@2|Bacteria,1VG1N@1239|Firmicutes,24QK8@186801|Clostridia,27P6W@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
KFPFDFKC_03893	633697.EubceDRAFT1_2302	3.78e-271	744.0	COG1690@1|root,COG1690@2|Bacteria,1TPJ2@1239|Firmicutes,2481V@186801|Clostridia,25VDC@186806|Eubacteriaceae	186801|Clostridia	S	tRNA-splicing ligase RtcB	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
KFPFDFKC_03896	658086.HMPREF0994_03639	0.0	948.0	COG3534@1|root,COG3534@2|Bacteria,1TPG2@1239|Firmicutes,24AVP@186801|Clostridia	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-L-AF_C,Cadherin-like,DUF1080
KFPFDFKC_03897	1410632.JHWW01000001_gene941	3.03e-251	703.0	COG2272@1|root,COG2272@2|Bacteria,1UXY5@1239|Firmicutes,249A6@186801|Clostridia,27UGZ@186928|unclassified Lachnospiraceae	186801|Clostridia	I	Carboxylesterase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase,Glyco_hydro_43
KFPFDFKC_03898	642492.Clole_1281	5.3e-302	827.0	COG3534@1|root,COG3534@2|Bacteria,1TPJ0@1239|Firmicutes,25EH6@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
KFPFDFKC_03899	1226325.HMPREF1548_05324	3.74e-246	690.0	COG3664@1|root,COG3664@2|Bacteria,1TQGI@1239|Firmicutes,2490Q@186801|Clostridia,36GCA@31979|Clostridiaceae	186801|Clostridia	K	family 39	-	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	AraC_binding,Glyco_hydro_39,HTH_18
KFPFDFKC_03900	397291.C804_04886	3.33e-90	276.0	COG4977@1|root,COG4977@2|Bacteria,1UJZB@1239|Firmicutes,25FFH@186801|Clostridia,27NE9@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
KFPFDFKC_03901	518637.EUBIFOR_00731	2.23e-126	360.0	COG2020@1|root,COG2020@2|Bacteria,1V3IZ@1239|Firmicutes	1239|Firmicutes	O	Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF218,PEMT
KFPFDFKC_03902	1256908.HMPREF0373_02042	5.47e-176	489.0	COG3910@1|root,COG3910@2|Bacteria,1TSWP@1239|Firmicutes,249W3@186801|Clostridia,25UUH@186806|Eubacteriaceae	186801|Clostridia	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,AAA_23
KFPFDFKC_03903	1235792.C808_04909	1.72e-51	165.0	COG1943@1|root,COG1943@2|Bacteria,1TSQ0@1239|Firmicutes,25CMS@186801|Clostridia,27U60@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
KFPFDFKC_03904	585394.RHOM_05755	6.69e-117	362.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia	186801|Clostridia	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
KFPFDFKC_03905	658086.HMPREF0994_03639	0.0	956.0	COG3534@1|root,COG3534@2|Bacteria,1TPG2@1239|Firmicutes,24AVP@186801|Clostridia	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-L-AF_C,Cadherin-like,DUF1080
KFPFDFKC_03906	658086.HMPREF0994_03645	0.0	903.0	COG1653@1|root,COG3693@1|root,COG1653@2|Bacteria,COG3693@2|Bacteria,1UHTC@1239|Firmicutes,248KD@186801|Clostridia,27JSU@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolase family 10	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3,Beta_helix,Glyco_hydro_10,Peptidase_S9
KFPFDFKC_03907	877418.ATWV01000004_gene1861	1.9e-203	579.0	COG0534@1|root,COG0534@2|Bacteria,2J674@203691|Spirochaetes	203691|Spirochaetes	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
KFPFDFKC_03909	1336245.JAGO01000001_gene1090	7.56e-43	153.0	COG0627@1|root,COG0627@2|Bacteria,1N3VN@1224|Proteobacteria,1RYER@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
KFPFDFKC_03910	1227349.C170_17832	2.18e-56	188.0	COG0627@1|root,COG0627@2|Bacteria,1TPA9@1239|Firmicutes,4HD64@91061|Bacilli,26RX9@186822|Paenibacillaceae	91061|Bacilli	S	esterase	estA	-	-	ko:K03930	-	-	-	-	ko00000,ko01000	-	CE1	-	Esterase
KFPFDFKC_03911	1280666.ATVS01000025_gene2877	1.54e-301	832.0	COG3534@1|root,COG3534@2|Bacteria,1VS1P@1239|Firmicutes,24BH3@186801|Clostridia,4C1VY@830|Butyrivibrio	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminus	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
KFPFDFKC_03912	658086.HMPREF0994_03785	3.57e-311	876.0	COG2382@1|root,COG2382@2|Bacteria,1V888@1239|Firmicutes,24CN5@186801|Clostridia,27M6U@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Dockerin_1,Esterase
KFPFDFKC_03913	658086.HMPREF0994_03797	1.97e-79	254.0	COG1609@1|root,COG1609@2|Bacteria,1V22B@1239|Firmicutes,24FZB@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
KFPFDFKC_03914	1280680.AUJU01000017_gene3826	3.26e-211	608.0	COG1653@1|root,COG1653@2|Bacteria,1V0Q4@1239|Firmicutes,24CCN@186801|Clostridia,4BYEJ@830|Butyrivibrio	186801|Clostridia	G	transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
KFPFDFKC_03915	658086.HMPREF0994_03647	2.34e-142	410.0	COG0395@1|root,COG0395@2|Bacteria,1TRB1@1239|Firmicutes,2488P@186801|Clostridia,27MH0@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K17320	ko02010,map02010	M00207,M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
KFPFDFKC_03916	658086.HMPREF0994_03648	3.05e-168	476.0	COG4209@1|root,COG4209@2|Bacteria,1TSTC@1239|Firmicutes,24AFM@186801|Clostridia,27M8N@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K17319	ko02010,map02010	M00207,M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
KFPFDFKC_03917	658086.HMPREF0994_03796	1.23e-190	553.0	COG3509@1|root,COG3509@2|Bacteria,1UZP5@1239|Firmicutes,24AU4@186801|Clostridia	186801|Clostridia	Q	Esterase PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Esterase_phd
KFPFDFKC_03918	1304880.JAGB01000002_gene1700	4.86e-170	495.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
KFPFDFKC_03919	1449050.JNLE01000003_gene1418	7.58e-174	497.0	COG1680@1|root,COG1680@2|Bacteria,1UC2C@1239|Firmicutes,24B3Q@186801|Clostridia,36FP4@31979|Clostridiaceae	186801|Clostridia	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
KFPFDFKC_03920	658086.HMPREF0994_03790	2.21e-127	379.0	COG1680@1|root,COG1680@2|Bacteria,1UC2C@1239|Firmicutes,24B3Q@186801|Clostridia,27QDK@186928|unclassified Lachnospiraceae	186801|Clostridia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
KFPFDFKC_03921	411469.EUBHAL_01641	2.02e-23	96.3	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,248FK@186801|Clostridia,25VWT@186806|Eubacteriaceae	186801|Clostridia	S	Oxidoreductase, aldo keto reductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,MerR_1
KFPFDFKC_03922	1329250.WOSG25_090490	0.0	914.0	COG3507@1|root,COG3507@2|Bacteria,1TP5K@1239|Firmicutes,4HA16@91061|Bacilli,4AXIH@81850|Leuconostocaceae	91061|Bacilli	G	Glycosyl hydrolases family 43	xynB	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	DUF1349,Glyco_hydro_43
KFPFDFKC_03924	592026.GCWU0000282_002501	5.86e-89	270.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia	186801|Clostridia	K	Belongs to the ParB family	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
KFPFDFKC_03925	622312.ROSEINA2194_04257	1.23e-104	301.0	2F5T1@1|root,33YBX@2|Bacteria,1VW15@1239|Firmicutes,2517G@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03926	1235800.C819_01638	9.17e-116	345.0	COG3039@1|root,COG3039@2|Bacteria,1TPFS@1239|Firmicutes,249JM@186801|Clostridia,27JF9@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
KFPFDFKC_03927	411902.CLOBOL_05064	1.45e-114	342.0	COG3039@1|root,COG3039@2|Bacteria,1TPFS@1239|Firmicutes,249JM@186801|Clostridia,2205J@1506553|Lachnoclostridium	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
KFPFDFKC_03928	397288.C806_00243	3.36e-148	444.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,27KEE@186928|unclassified Lachnospiraceae	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal
KFPFDFKC_03929	483218.BACPEC_02749	6e-150	423.0	COG3503@1|root,COG3503@2|Bacteria,1V8H3@1239|Firmicutes,24JRC@186801|Clostridia,26BGN@186813|unclassified Clostridiales	186801|Clostridia	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
KFPFDFKC_03930	622312.ROSEINA2194_03927	3.18e-52	181.0	COG3501@1|root,COG3501@2|Bacteria,1V3I5@1239|Firmicutes,24GKG@186801|Clostridia	186801|Clostridia	F	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
KFPFDFKC_03931	622312.ROSEINA2194_00384	9.58e-162	457.0	COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia	186801|Clostridia	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
KFPFDFKC_03932	622312.ROSEINA2194_01879	1.92e-59	186.0	2E3N2@1|root,32YK7@2|Bacteria,1VEYM@1239|Firmicutes,24QJ0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03933	1280698.AUJS01000100_gene153	2.62e-128	367.0	COG2039@1|root,COG2039@2|Bacteria,1TRRX@1239|Firmicutes,248T4@186801|Clostridia,27W6C@189330|Dorea	186801|Clostridia	O	Pyroglutamyl peptidase	pcp	-	3.4.19.3	ko:K01304	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C15
KFPFDFKC_03934	585394.RHOM_03705	1.81e-91	297.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
KFPFDFKC_03935	585394.RHOM_03710	1.61e-131	396.0	COG0845@1|root,COG0845@2|Bacteria,1V96V@1239|Firmicutes,24BEV@186801|Clostridia	186801|Clostridia	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
KFPFDFKC_03936	585394.RHOM_03715	1.91e-219	620.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,24AWU@186801|Clostridia	186801|Clostridia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
KFPFDFKC_03938	585394.RHOM_03725	1.45e-128	370.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia	186801|Clostridia	V	ABC transporter	lolD	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
KFPFDFKC_03939	585394.RHOM_03730	7.96e-115	335.0	COG4912@1|root,COG4912@2|Bacteria,1TQII@1239|Firmicutes,248N8@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
KFPFDFKC_03940	411902.CLOBOL_06104	1.72e-112	331.0	COG0483@1|root,COG0483@2|Bacteria,1TR4E@1239|Firmicutes,24KJZ@186801|Clostridia,22041@1506553|Lachnoclostridium	186801|Clostridia	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
KFPFDFKC_03942	478749.BRYFOR_07844	2.99e-73	238.0	COG5464@1|root,COG5464@2|Bacteria,1V3CA@1239|Firmicutes,24H4R@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
KFPFDFKC_03943	641112.ACOK01000097_gene867	1.84e-79	253.0	COG5464@1|root,COG5464@2|Bacteria,1V3CA@1239|Firmicutes,24H4R@186801|Clostridia,3WK37@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
KFPFDFKC_03944	585394.RHOM_10995	0.0	1002.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia	186801|Clostridia	G	beta-galactosidase	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
KFPFDFKC_03945	33035.JPJF01000061_gene3670	0.0	1733.0	COG1196@1|root,COG3867@1|root,COG5492@1|root,COG1196@2|Bacteria,COG3867@2|Bacteria,COG5492@2|Bacteria,1VUQN@1239|Firmicutes,24CDA@186801|Clostridia	186801|Clostridia	N	endoglucanase-related protein, glucosyl hydrolase family 9 protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,F5_F8_type_C,FIVAR,Flg_new,RHS_repeat,SH3_3,SLH,fn3
KFPFDFKC_03946	397291.C804_04887	0.0	1083.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,27J28@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
KFPFDFKC_03947	397291.C804_04823	6.65e-155	464.0	COG2972@1|root,COG2972@2|Bacteria,1TPUF@1239|Firmicutes,2491H@186801|Clostridia,27JGZ@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase
KFPFDFKC_03948	585394.RHOM_05765	3.41e-174	509.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1UYK2@1239|Firmicutes,247MJ@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
KFPFDFKC_03949	397291.C804_04825	0.0	993.0	COG1653@1|root,COG1653@2|Bacteria,1TQWF@1239|Firmicutes,24CWD@186801|Clostridia,27IIE@186928|unclassified Lachnospiraceae	186801|Clostridia	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
KFPFDFKC_03950	397291.C804_04826	3.21e-193	540.0	COG4209@1|root,COG4209@2|Bacteria,1TQ64@1239|Firmicutes,24YP3@186801|Clostridia,27KGJ@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
KFPFDFKC_03951	397291.C804_04827	9.53e-177	497.0	COG0395@1|root,COG0395@2|Bacteria,1TP14@1239|Firmicutes,2481Z@186801|Clostridia,27KBY@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17320	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
KFPFDFKC_03952	1226325.HMPREF1548_05296	1.45e-200	565.0	COG3405@1|root,COG3405@2|Bacteria,1U1E1@1239|Firmicutes,24878@186801|Clostridia,36FZI@31979|Clostridiaceae	186801|Clostridia	G	family 8	-	-	3.2.1.156	ko:K15531	-	-	-	-	ko00000,ko01000	-	GH8	-	Dockerin_1,Glyco_hydro_8,Polysacc_deac_1
KFPFDFKC_03953	1280390.CBQR020000071_gene1456	1.75e-316	904.0	2DB7A@1|root,2Z7KK@2|Bacteria,1TQ2C@1239|Firmicutes,4HFKE@91061|Bacilli,26S01@186822|Paenibacillaceae	91061|Bacilli	S	Glycosyl hydrolase family 115	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_115
KFPFDFKC_03954	585394.RHOM_05745	5.07e-251	707.0	COG2755@1|root,COG2755@2|Bacteria,1TPYH@1239|Firmicutes,2486S@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Lipase_GDSL_2
KFPFDFKC_03955	1163671.JAGI01000002_gene2603	1.21e-246	692.0	COG3507@1|root,COG3507@2|Bacteria,1TP5K@1239|Firmicutes,247R2@186801|Clostridia,36ES1@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.37,3.2.1.55	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	-	R01433,R01762	RC00467	ko00000,ko00001,ko01000	-	GH43,GH51	-	Glyco_hydro_43
KFPFDFKC_03956	585394.RHOM_10990	1.67e-180	509.0	COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,248WQ@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
KFPFDFKC_03957	622312.ROSEINA2194_04213	1.03e-250	696.0	COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia	186801|Clostridia	G	ABC transporter, solute-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
KFPFDFKC_03958	622312.ROSEINA2194_04214	0.0	880.0	COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,247MA@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
KFPFDFKC_03959	622312.ROSEINA2194_04215	1.71e-180	504.0	COG3833@1|root,COG3833@2|Bacteria,1TRB7@1239|Firmicutes,248A7@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
KFPFDFKC_03960	622312.ROSEINA2194_04216	0.0	1265.0	2DBG1@1|root,2Z91R@2|Bacteria,1TQV4@1239|Firmicutes,24CK0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03961	622312.ROSEINA2194_04217	6.33e-50	157.0	2EAM1@1|root,334PP@2|Bacteria,1VI13@1239|Firmicutes,24ST8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03962	622312.ROSEINA2194_04218	2e-204	567.0	COG2207@1|root,COG2207@2|Bacteria,1V0IW@1239|Firmicutes,24BME@186801|Clostridia	186801|Clostridia	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
KFPFDFKC_03963	622312.ROSEINA2194_04219	0.0	1747.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia	186801|Clostridia	G	beta-galactosidase	lacZ	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
KFPFDFKC_03964	585394.RHOM_10945	1.64e-252	695.0	COG3867@1|root,COG3867@2|Bacteria,1TQDZ@1239|Firmicutes,24CPM@186801|Clostridia	186801|Clostridia	G	arabinogalactan	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_53
KFPFDFKC_03965	622312.ROSEINA2194_02310	7.7e-264	727.0	COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,247U8@186801|Clostridia	186801|Clostridia	G	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
KFPFDFKC_03966	622312.ROSEINA2194_02311	0.0	939.0	COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,247ZN@186801|Clostridia	186801|Clostridia	G	UDPglucose--hexose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
KFPFDFKC_03967	585394.RHOM_10930	3.4e-248	686.0	COG0436@1|root,COG0436@2|Bacteria,1TP36@1239|Firmicutes,248ZV@186801|Clostridia	186801|Clostridia	E	Aminotransferase	yhdR	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
KFPFDFKC_03968	622312.ROSEINA2194_02313	3.26e-217	604.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
KFPFDFKC_03969	585394.RHOM_10920	1.9e-97	296.0	COG1266@1|root,COG1266@2|Bacteria,1VF60@1239|Firmicutes,24QSC@186801|Clostridia	186801|Clostridia	S	CAAX amino terminal protease family protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
KFPFDFKC_03970	585394.RHOM_10915	1.08e-60	187.0	COG4496@1|root,COG4496@2|Bacteria,1VA04@1239|Firmicutes,24MX9@186801|Clostridia	186801|Clostridia	S	protein, YerC YecD	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
KFPFDFKC_03971	585394.RHOM_10910	1.69e-89	268.0	COG0789@1|root,COG0789@2|Bacteria,1V1M9@1239|Firmicutes,24FUE@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1836
KFPFDFKC_03972	585394.RHOM_10905	0.0	1194.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia	186801|Clostridia	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
KFPFDFKC_03974	622312.ROSEINA2194_02319	1.17e-254	709.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
KFPFDFKC_03975	1469948.JPNB01000001_gene1979	2.57e-115	346.0	COG2602@1|root,COG2602@2|Bacteria,1VZ0X@1239|Firmicutes,24CE9@186801|Clostridia,36VJX@31979|Clostridiaceae	186801|Clostridia	V	Penicillin binding protein transpeptidase domain	-	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	Transpeptidase
KFPFDFKC_03976	742765.HMPREF9457_03130	1.47e-91	289.0	COG2602@1|root,COG4219@1|root,COG2602@2|Bacteria,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,249NV@186801|Clostridia,27V9M@189330|Dorea	186801|Clostridia	KTV	BlaR1 peptidase M56	blaR	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	Peptidase_M56,Transpeptidase
KFPFDFKC_03977	1235800.C819_00706	8.45e-289	791.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,248J7@186801|Clostridia,27J3U@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
KFPFDFKC_03978	768706.Desor_0952	1.39e-125	367.0	2DBNE@1|root,2ZA3J@2|Bacteria,1V334@1239|Firmicutes,24H2J@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF1837)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1837
KFPFDFKC_03979	97139.C824_04774	0.0	1521.0	COG1204@1|root,COG1204@2|Bacteria,1TT19@1239|Firmicutes,2494I@186801|Clostridia,36GX7@31979|Clostridiaceae	186801|Clostridia	L	Dead deah box helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
KFPFDFKC_03980	1280682.AUKA01000001_gene1480	3.02e-294	804.0	COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,248JG@186801|Clostridia,4BX89@830|Butyrivibrio	186801|Clostridia	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,HhH-GPD,Transposase_20
KFPFDFKC_03981	742738.HMPREF9460_02091	1.95e-165	472.0	COG1192@1|root,COG1192@2|Bacteria,1VHM0@1239|Firmicutes,24FNK@186801|Clostridia	186801|Clostridia	D	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
KFPFDFKC_03982	622312.ROSEINA2194_01811	1.95e-214	593.0	2F105@1|root,33U1P@2|Bacteria,1VUDP@1239|Firmicutes,2503G@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03983	622312.ROSEINA2194_01810	4.53e-200	553.0	COG1192@1|root,COG1192@2|Bacteria,1VBJ6@1239|Firmicutes,24P57@186801|Clostridia	186801|Clostridia	D	Involved in chromosome partitioning	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03984	352165.HMPREF7215_0139	8.25e-46	162.0	COG2265@1|root,COG2265@2|Bacteria,3TAIZ@508458|Synergistetes	508458|Synergistetes	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
KFPFDFKC_03985	622312.ROSEINA2194_00603	1.77e-81	246.0	COG0127@1|root,COG0127@2|Bacteria,1V85S@1239|Firmicutes,24KX4@186801|Clostridia	186801|Clostridia	F	Ham1 family	-	-	-	-	-	-	-	-	-	-	-	-	Ham1p_like
KFPFDFKC_03987	573061.Clocel_1643	1.75e-122	355.0	COG2820@1|root,COG2820@2|Bacteria,1UFD2@1239|Firmicutes,24ICS@186801|Clostridia	186801|Clostridia	F	Phosphorylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
KFPFDFKC_03988	1280680.AUJU01000031_gene3595	8.23e-98	290.0	COG0237@1|root,COG0237@2|Bacteria,1VHNA@1239|Firmicutes,24KBU@186801|Clostridia,4BW2U@830|Butyrivibrio	186801|Clostridia	H	dephospho-CoA kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03989	411462.DORLON_01304	3.27e-48	155.0	296J0@1|root,347SA@2|Bacteria,1VZKB@1239|Firmicutes,252U1@186801|Clostridia,27WQ9@189330|Dorea	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
KFPFDFKC_03991	622312.ROSEINA2194_00596	1.85e-72	218.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26,HTH_3,HTH_31
KFPFDFKC_03992	511680.BUTYVIB_01768	1.21e-174	494.0	COG1502@1|root,COG1502@2|Bacteria,1TRJE@1239|Firmicutes,248ZE@186801|Clostridia,4BYQD@830|Butyrivibrio	186801|Clostridia	I	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
KFPFDFKC_03993	574375.BAGA_15745	5.4e-164	463.0	2E47H@1|root,32Z3D@2|Bacteria,1VWJ7@1239|Firmicutes,4HZSQ@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_03994	180332.JTGN01000015_gene1129	5.35e-131	396.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSN6@1239|Firmicutes,24D7T@186801|Clostridia	186801|Clostridia	T	response regulator	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
KFPFDFKC_03995	180332.JTGN01000015_gene1128	7.99e-196	569.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,248RT@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
KFPFDFKC_03996	500632.CLONEX_00407	3.95e-109	335.0	COG1653@1|root,COG1653@2|Bacteria,1TQ0V@1239|Firmicutes,2481M@186801|Clostridia	186801|Clostridia	G	solute-binding protein	lacE	-	-	ko:K10188	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	SBP_bac_1,SBP_bac_8
KFPFDFKC_03997	1163671.JAGI01000002_gene2752	7.05e-150	441.0	COG1653@1|root,COG1653@2|Bacteria,1TQ0V@1239|Firmicutes,2481M@186801|Clostridia,36E6U@31979|Clostridiaceae	186801|Clostridia	G	Extracellular solute-binding protein	lacE	-	-	ko:K02027,ko:K10188	ko02010,map02010	M00199,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.4	-	-	SBP_bac_1,SBP_bac_8
KFPFDFKC_03998	1469948.JPNB01000002_gene2491	8.25e-137	395.0	COG1175@1|root,COG1175@2|Bacteria,1TPMR@1239|Firmicutes,2494U@186801|Clostridia,36EUX@31979|Clostridiaceae	186801|Clostridia	P	PFAM Binding-protein-dependent transport	-	-	-	ko:K02025,ko:K10189,ko:K10241	ko02010,map02010	M00199,M00206,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.23,3.A.1.1.4	-	-	BPD_transp_1
KFPFDFKC_03999	1235790.C805_00783	3.76e-116	341.0	COG0395@1|root,COG0395@2|Bacteria,1TSGI@1239|Firmicutes,24BDH@186801|Clostridia,25VTP@186806|Eubacteriaceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10190	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	BPD_transp_1
KFPFDFKC_04000	1408306.JHXX01000003_gene1412	1.96e-70	216.0	COG0454@1|root,COG0456@2|Bacteria,1VAJN@1239|Firmicutes,24H93@186801|Clostridia,4BXFH@830|Butyrivibrio	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
KFPFDFKC_04002	1121115.AXVN01000035_gene3826	2.48e-114	330.0	COG1418@1|root,COG1418@2|Bacteria,1UI0F@1239|Firmicutes,24GIY@186801|Clostridia,3XZYU@572511|Blautia	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K09163	-	-	-	-	ko00000	-	-	-	HD
KFPFDFKC_04003	515620.EUBELI_20542	1.02e-85	268.0	COG0484@1|root,COG0484@2|Bacteria,1V4K2@1239|Firmicutes,24I8B@186801|Clostridia	186801|Clostridia	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
KFPFDFKC_04004	140626.JHWB01000022_gene2045	8.62e-107	315.0	COG0406@1|root,COG0406@2|Bacteria,1U7UE@1239|Firmicutes,24F5B@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
KFPFDFKC_04005	411459.RUMOBE_02708	2.52e-95	291.0	COG1609@1|root,COG1609@2|Bacteria,1UK1H@1239|Firmicutes,249XN@186801|Clostridia,3XZFY@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
KFPFDFKC_04006	411474.COPEUT_00629	5.08e-23	99.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	cysA	-	3.6.3.25	ko:K02045,ko:K02052	ko00920,ko02010,ko02024,map00920,map02010,map02024	M00185,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_2
KFPFDFKC_04007	1410632.JHWW01000013_gene237	8.08e-13	68.9	COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,247VM@186801|Clostridia,27NJZ@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
KFPFDFKC_04008	411462.DORLON_00099	9.08e-202	564.0	2C2TA@1|root,2Z7T7@2|Bacteria,1TS53@1239|Firmicutes,248BA@186801|Clostridia,27WMG@189330|Dorea	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
KFPFDFKC_04009	585394.RHOM_04700	2.78e-185	531.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia	186801|Clostridia	E	amino acid carrier protein	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
KFPFDFKC_04010	585394.RHOM_04710	6.85e-157	446.0	COG2035@1|root,COG2035@2|Bacteria,1UYD5@1239|Firmicutes,24B08@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
KFPFDFKC_04011	622312.ROSEINA2194_02642	0.0	890.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia	186801|Clostridia	V	Abc transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
KFPFDFKC_04012	585394.RHOM_04720	0.0	940.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
KFPFDFKC_04013	622312.ROSEINA2194_02159	4.96e-99	295.0	COG2186@1|root,COG2186@2|Bacteria,1V1Y0@1239|Firmicutes,249UW@186801|Clostridia	186801|Clostridia	K	FCD domain	pdhR	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
KFPFDFKC_04014	556261.HMPREF0240_00860	2.29e-151	452.0	COG2199@1|root,COG2199@2|Bacteria,1TQKY@1239|Firmicutes,25EP8@186801|Clostridia,36V2W@31979|Clostridiaceae	186801|Clostridia	T	Pfam:Cache_1	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP,dCache_1
KFPFDFKC_04015	585394.RHOM_11415	8.24e-115	350.0	COG0840@1|root,COG0840@2|Bacteria,1TQW8@1239|Firmicutes,24EE8@186801|Clostridia	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal
KFPFDFKC_04016	585394.RHOM_11560	5.58e-239	672.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
KFPFDFKC_04017	397287.C807_00219	1.88e-83	254.0	COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,249FE@186801|Clostridia,27U4Q@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Region found in RelA / SpoT proteins	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT,Response_reg
KFPFDFKC_04018	622312.ROSEINA2194_02885	1.61e-203	571.0	COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,24919@186801|Clostridia	186801|Clostridia	E	Aminotransferase	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
KFPFDFKC_04019	622312.ROSEINA2194_02884	1.12e-95	282.0	COG4720@1|root,COG4720@2|Bacteria,1V1E7@1239|Firmicutes,25CJR@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
KFPFDFKC_04020	622312.ROSEINA2194_02871	4.53e-41	135.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia	186801|Clostridia	K	Cold shock protein	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
KFPFDFKC_04021	585394.RHOM_11385	5.98e-77	233.0	2C2B5@1|root,32RA4@2|Bacteria,1V6P1@1239|Firmicutes,24N51@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_04022	585394.RHOM_11380	4.37e-235	655.0	COG1362@1|root,COG1362@2|Bacteria,1TQ3Z@1239|Firmicutes,248UP@186801|Clostridia	186801|Clostridia	E	M18 family aminopeptidase	-	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
KFPFDFKC_04023	622312.ROSEINA2194_02860	1.55e-126	378.0	COG5279@1|root,COG5279@2|Bacteria,1TY2Q@1239|Firmicutes,24BDS@186801|Clostridia	186801|Clostridia	D	protein involved in cytokinesis, contains TGc (transglutaminase protease-like) domain	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
KFPFDFKC_04024	585394.RHOM_11375	2.15e-164	464.0	COG1307@1|root,COG1307@2|Bacteria,1TSKD@1239|Firmicutes,24AE9@186801|Clostridia	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
KFPFDFKC_04025	585394.RHOM_11370	4.99e-174	501.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
KFPFDFKC_04026	622312.ROSEINA2194_02856	4.51e-228	639.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia	186801|Clostridia	M	Membrane protein involved in D-alanine export	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
KFPFDFKC_04027	585394.RHOM_11360	5.29e-121	355.0	COG2755@1|root,COG2755@2|Bacteria,1V2MD@1239|Firmicutes,24FWG@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
KFPFDFKC_04029	457415.HMPREF1006_00874	2.31e-113	359.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,3TB48@508458|Synergistetes	508458|Synergistetes	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,Response_reg
KFPFDFKC_04030	585394.RHOM_11345	2.21e-248	690.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
KFPFDFKC_04031	622312.ROSEINA2194_00725	2.58e-32	114.0	COG1314@1|root,COG1314@2|Bacteria,1VG46@1239|Firmicutes	1239|Firmicutes	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
KFPFDFKC_04032	622312.ROSEINA2194_00724	0.0	1212.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia	186801|Clostridia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
KFPFDFKC_04033	585394.RHOM_11330	1.56e-98	287.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia	186801|Clostridia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
KFPFDFKC_04035	397290.C810_04867	3.35e-31	117.0	2B1N9@1|root,31U3S@2|Bacteria,1USHS@1239|Firmicutes,25AHW@186801|Clostridia,27QGU@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_04036	626523.GCWU000342_02293	1.14e-131	386.0	COG1609@1|root,COG1609@2|Bacteria,1TSRM@1239|Firmicutes,24BFS@186801|Clostridia	186801|Clostridia	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_4
KFPFDFKC_04037	1226325.HMPREF1548_06302	2.68e-291	802.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,36F3K@31979|Clostridiaceae	186801|Clostridia	G	Carbohydrate kinase, FGGY	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
KFPFDFKC_04038	658086.HMPREF0994_00224	3.09e-100	295.0	28PTU@1|root,2ZCEZ@2|Bacteria,1U95M@1239|Firmicutes,247W6@186801|Clostridia,27M68@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4867
KFPFDFKC_04039	1121115.AXVN01000030_gene3609	0.0	897.0	COG2407@1|root,COG2407@2|Bacteria,1TQDX@1239|Firmicutes,247N8@186801|Clostridia,3XZ0K@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Fucose_iso_C
KFPFDFKC_04040	585394.RHOM_04815	1.41e-109	337.0	COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG4991@2|Bacteria,1TRKG@1239|Firmicutes,249Y4@186801|Clostridia	186801|Clostridia	MT	NlpC p60 family protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3
KFPFDFKC_04042	622312.ROSEINA2194_00293	9.74e-38	127.0	COG1925@1|root,COG1925@2|Bacteria,1VEJ5@1239|Firmicutes,24R2F@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
KFPFDFKC_04043	585394.RHOM_05135	0.0	1204.0	COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,248ZI@186801|Clostridia	186801|Clostridia	L	helicase	dinG	-	3.1.12.1,3.6.4.12	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	-	-	-	DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1
KFPFDFKC_04044	622312.ROSEINA2194_01402	8.35e-199	552.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia	186801|Clostridia	K	lysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
KFPFDFKC_04045	585394.RHOM_05145	0.0	2249.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia	186801|Clostridia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
KFPFDFKC_04047	411459.RUMOBE_00681	9.93e-151	429.0	COG3177@1|root,COG3177@2|Bacteria,1TZWX@1239|Firmicutes,247MZ@186801|Clostridia,3Y0W4@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Fic
KFPFDFKC_04048	1226325.HMPREF1548_01463	1.65e-17	83.6	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,36E5J@31979|Clostridiaceae	186801|Clostridia	K	An automated process has identified a potential problem with this gene model	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
KFPFDFKC_04049	1226325.HMPREF1548_01463	9.32e-43	156.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,36E5J@31979|Clostridiaceae	186801|Clostridia	K	An automated process has identified a potential problem with this gene model	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
KFPFDFKC_04050	1519439.JPJG01000008_gene1174	1.25e-68	214.0	2CBD1@1|root,32SNG@2|Bacteria,1VAVB@1239|Firmicutes,24Q8B@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
KFPFDFKC_04051	428125.CLOLEP_02050	8.61e-196	558.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,3WH3T@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
KFPFDFKC_04052	1304866.K413DRAFT_4421	7.85e-120	358.0	28IAA@1|root,2Z8CW@2|Bacteria,1TQHP@1239|Firmicutes,248TG@186801|Clostridia,36F51@31979|Clostridiaceae	186801|Clostridia	S	DHHW protein	-	-	-	-	-	-	-	-	-	-	-	-	DHHW
KFPFDFKC_04053	585394.RHOM_05155	4.85e-155	439.0	COG1387@1|root,COG1387@2|Bacteria,1TRKS@1239|Firmicutes,249TM@186801|Clostridia	186801|Clostridia	E	Histidinol phosphate phosphatase, HisJ family	hisK	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
KFPFDFKC_04054	679200.HMPREF9333_01948	3.71e-71	223.0	2DBC6@1|root,2Z8BZ@2|Bacteria,1TQXM@1239|Firmicutes,2484N@186801|Clostridia	186801|Clostridia	S	Replication initiator protein A	-	-	-	-	-	-	-	-	-	-	-	-	RepA_N
## 3562 queries scanned
## Total time (seconds): 473.1948323249817
## Rate: 7.53 q/s