LOCUS       gnlProkkaJEMIGLEB_18   22141 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JEMIGLEB_18.
ACCESSION   gnlProkkaJEMIGLEB_18
VERSION     gnlProkkaJEMIGLEB_18
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 21:06:36
            Original ID  :: gnl|Prokka|JEMIGLEB_18
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 18179
            Orig. end    :: 40320
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22141
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[5000:17141]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..17141
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..22141
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22141
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             1015..2757
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_18"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.2e-30,
                     bitscore: 97.9, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENTHGLRLRRAEKEDCRFLYELRNEEEVRKNSFQTGIFSYEDHV
                     AWFERKLEEKNTRIYILEQDGERIGQARVDLEGQNGEISYALCLRARGHGYSKWMLGSI
                     EEELREQAVCRKLIAEVKRENIASQKIFETLSYIAVPADYGYVFEKKIPLFTIIMCTYN
                     SAQTLATAVESVRNQEFGGWEMQILDNGSKDESVEKLQEYEKSDDRIKCIYRKDNIGWG
                     KGISECLKTSAGGYMMFLGADDYLATEHTLTEVADEVKKNHPQIIFTGTYYAKYEQGEY
                     HIIRYTLPENKVYKGDGERLIRMTELMHNVYYNSAMHYLKIDFLKQNGMDFYDPFYIDS
                     QTMTEAIVKAEKIVVMSQPEYVLTLNTSQTAKRTVYDYNVERQWNSIKEILPPTTAGRE
                     EAVSYVARRVLDNIAAMCQSIVLGEALCDREMNTIEKSIPERFARVEEMISTDAMGEMM
                     NYAGREEYAECLIGAAGVTCWICKKNKRLSDEICHNSKWLAEFVEVAMEVDETTGMVVW
                     KKRFDRDAGDRLLRIFQNSWNRFKTGVELVLKDDVWYEDIGIREKLCEEKESGVTYARR
                     SIDQ"
     CDS             2879..3913
                     /locus_tag="ctg18_19"
                     /transl_table=11
                     /translation="MNLYEKMKSGVYVIAEMSANHAGKIENAFKIIEEAAKAGADCVKI
                     QTYTADTLTIDCDDEPYRIKGGLWDGYNYYQLYQEAYTPWEWQQQLKDKCEEVGVDFLS
                     TPFDRTAVDFLEGIGIEFYKIASFELVDIPLIEYTAGKGKPMIMSCGMASEEEIAEALA
                     ACRRQGNEQVVLLKCCSQYPAQYEDMNVSVIPDMKERFGVPVGLSDHSMGSLADVVAVS
                     LGAQVIEKHVCLSHEIENPDAAFSMEMKDFAQMVQDVRNACLIKGRPTYELTEHEKDSL
                     KYRRSLVAVKPIAEGELFTEENVRSIRPAIGIKPKYYKALLGKPAKKAYRFGEPIGQLE
                     VEQI"
     CDS             3910..4977
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_tran_28_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_20"
                     /sec_met_domain="Glyco_tran_28_C (E-value: 1.1e-08,
                     bitscore: 26.4, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVFRADANETAATGHLMRCMTIAEACREKGVECEFWLAEDKETE
                     RLRQAGFSYRILGSQWDDLEKELPFLERQLDDLDRQGKKVTYLVADSYQATPRYLGKLN
                     DRIPVLYIDDMRMQIYPVAAVLQYIPVRTKNSLNIEERSEQNMPVYLRGFRYAPLRKEF
                     LKSHVEQREKSILITTGGTDTYNIAGRLLQECLDKDVFQEYRFHVIVGNMNSHEAELCG
                     LSERDKRICIHKNISNMSDYMHSCELAVSASGTTLLELCACGIPAICFSFADNQMAFAA
                     SMDNYGAMCYVGDAREEDNIERIICMRLTELAGQEKLRKRQVACMKALVDGRGAERIAD
                     FLICGNLNECDDIHK"
     CDS             5001..6125
                     /NRPS_PKS="Domain: Aminotran_1_2 (31-157). E-value: 4e-14.
                     Score: 44.3. Matches aSDomain:
                     nrpspksdomains_ctg18_21_Aminotran_1_2.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_1_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     409; E-value: 3.2e-124)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_21"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.5e-139,
                     bitscore: 456.6, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 1e-07, bitscore:
                     22.5, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.7e-14, bitscore:
                     44.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIPYGRQTIEEDDIQIVVDVLRSDYLTTGPKVAEFEKLVADYVGA
                     KYAVAISNDTAALHAACHAAGIGPGDEVITTPITFAASSNCVLYCGGTPVFADVDSKTY
                     NIDPEDIKRKITGKTKAIIPVHLAGQPCDMDEIHAIAKEHHLIVIEDAAHALGSEYKGK
                     MIGSMSDMTTFSFHPVKPITTGEGGMIVTNDETLYKKLVLFRSHGITRDESQMTRNEGS
                     WFYQQIDLGYNYRMTDIQCALGCTQMKKLDRFIARRREIVERYNEAFADCKNIVTPYQL
                     PDTKSGWHLYIIQVKNKDRKEVFDALREEGIGVNVHYIPVYYHPYYQEHGFKDVYCPVA
                     EELYTHIISLPIFPKLTDEQQDEVIEKVKKVAEN"
     aSDomain        5094..5471
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_21_Aminotran_1_2.1"
                     /evalue="4.00E-14"
                     /label="ctg18_21_Aminotran_1_2.1"
                     /locus_tag="ctg18_21"
                     /protein_end="157"
                     /protein_start="31"
                     /score="44.3"
                     /tool="antismash"
                     /translation="VAEFEKLVADYVGAKYAVAISNDTAALHAACHAAGIGPGDEVITT
                     PITFAASSNCVLYCGGTPVFADVDSKTYNIDPEDIKRKITGKTKAIIPVHLAGQPCDMD
                     EIHAIAKEHHLIVIEDAAHALG"
     CDS             6125..7300
                     /locus_tag="ctg18_22"
                     /transl_table=11
                     /translation="MNTGRNMKLLFFQWHSFMNKGIERGLKELEIPYDTFFYQFNDWEK
                     DDAFLEQFRAYLKAGAYTDVLSVNFSPLISMLCEELGIVYTAWVYDSPLHIRNLERLKN
                     SCNRIFFFDRGQAEEHRKDGVNAMHLPLAVDTEVFRINASKREKEDYRTDISLVGKLYQ
                     TEYSYFTAPLQGYIKGYLEGIVNAQGKVYGGYLIPELITDELLAQMNVEYTKVAKDGFV
                     MGRRELEFMLACETTGRERYMALALLSAHYPVDLYSTDVDKRLEKVRYRGYADYYSQMP
                     LAFSQSKINLNISLKTIRTGIPLRVIDVLGCGGFMLSNYQEELFEYFNIGEELVVYENI
                     EDLFYKAKYYLEHEDERKQIALAGVERVKRDFTFRERLRVMYGNSSADRRN"
     CDS             7281..9008
                     /locus_tag="ctg18_23"
                     /transl_table=11
                     /translation="MQTGETEMTNEQNEIITTIEKMLEMVKSGELPLDMCPISNFRTVY
                     YCALCYANDIKLAEQIAEEYCTVLQSLAANGARTEFCMMLELMIKSMKYEYEKRSYYEK
                     QNKILADKLEEMQNGTSVFDEILQCYEKNGINEKFLEDHTYQSLVSVKEKGSIELFKEI
                     SAKVYETALNCIRKKQVKKIVFLLKDSAEWSCEELYKRFNETSGYEVCVAVAPFFAGSQ
                     QAVSKMYLDTVQYFRERKIDTVEMYDIQKNRYKSWEEIGMPDIVFHLNPHYKAFAESSN
                     ICNFPLSILNVYIPYGIMIYGNVRQQYNQLSHMLYWKIFCETPLHKEMASKYADIGDIN
                     VVCSGYVKMDTFFDTCLQEKRKIWKISPRADEKKIKKIIYAPHWSIKDAVTGFGNFDKI
                     YKSLYEYVKKNETSTSWVFRPHPMLRVGAVQQGIFKSEEEYEEYLEMWRQLPNAQVIEN
                     GMYTDIFESSDAMILDSISFLGEYIYMHKPMLFLTRDRNTFNDFGKELVRVLYKTDGGN
                     LEGIKNFVEKNVIGNEDPMKERREEFFEKYMDYRNQNGMLASEYIKQYIDCLTEGDKE"
     CDS             9008..10006
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_24"
                     /sec_met_domain="PF04055 (E-value: 6.2e-22, bitscore: 70.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.1e-09, bitscore: 30.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.4e-07, bitscore: 23.4,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLTERYSKKLETTVNGRQISLDGVLLQLEVTNACNHKCMFCPNV
                     ESHRPKKMIDFELAKRVMKECADFLGADKRICFHMNGEPLLYKRLPELVEYSKKLGYEY
                     SFITTNGSLANEELLTRLFEAGLDSIKFSINAGSRETYKKIHGVDNYENAINALKFSWK
                     YREENGKKYKIFVSCVGIKQNYEELEAFNQMASCYCDEVVFYYPCGYAGQKLASLEDRC
                     DLSKLSVKSFEIRHTVPCAVLWNSINVTCEGYLSLCCSESDNRLIVEDINHIGVKEAWL
                     GEKMMTIREKHAKMNIEEMPCLSCVTETPYDITKIDKHLFALSLQNTKEML"
     CDS             10042..10779
                     /locus_tag="ctg18_25"
                     /transl_table=11
                     /translation="MRIKEKIENIDYNDTKLFFKKRAEKFQESNPYSVTMYQDNNEEIV
                     RQRNKKEIEKLMPLLHMEKEAKVLDVACGIGRWADALPEDIKEYCGMDFSEELVAIANK
                     RNHRNRFFYCVGGANEIAAVLKKNGKGLYNRILIVGILMYLNDVDMADSLRQIEKVCET
                     KSVICIREPIAIEERLTLKDFFSEELNDYYNAIYRTRDELMVSINEMFLNKGFRIKEEG
                     FLFDDDALNNRKETAQYYYILER"
     CDS             10786..11439
                     /locus_tag="ctg18_26"
                     /transl_table=11
                     /translation="MYREKVGIIGGFGAYATLNFYKRLLEEFASESERNYPHIIMDNNF
                     TMPSRTRALLYGEAYDEVVDGISDSIQLMMQNDVSKIILACGTAHYFLNDVYKKIPEAK
                     EKIVDIINIMGEELKLKDEGEVLVIAAEGALQKKLYQTRLKKYGIKCVNPDEEDFIDIR
                     YFIECVKRNELNEDLVHQFGNFLDKFGKRNVVLGCTEFPVLVEYIDKCQKQRVQ"
     CDS             11531..12133
                     /locus_tag="ctg18_27"
                     /transl_table=11
                     /translation="MSRYIFLFDLDSTVTKQEILPTISKRLGIYERMSELTESTMRGEI
                     PFKQSFLQRVELLKDVPVSEVNEMVSRIQLNNHLVDFIQKNHDRCHIVTGNLDVWIDGV
                     IRKLGMERNTFCSKAIVKNDYIEDVFNIVDKNAVIGQMVLPFVAIGDGNNDAEMIEAAE
                     VGIGYGGVREIAPAVLACASHAIYDEEKLVEFLERLL"
     CDS             12147..12797
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_28"
                     /sec_met_domain="NTP_transf_3 (E-value: 2.6e-14, bitscore:
                     45.2, seeds: 297, tool: rule-based-clusters)"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2e-07, bitscore:
                     22.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVSRTVIISCAGMGNRLGLGTTKALVEVEGKPLIMHHLEKLKDE
                     SDIRVVVGYQAEKVINVVRKYRKDVVFVFNHNYRETGTGASVALASQYANEYILSLDGD
                     LIIHPDDMKKILECDHEFVSGGIPDTDEPWMLQTYKDDGKEFVSAFSKNIGNYEWNGIT
                     QMKSAKIKNGQGHVFQLIEPYLPIPFLELRTREIDTVNDYERAVEWVRNNFRE"
     CDS             12831..12983
                     /locus_tag="ctg18_29"
                     /transl_table=11
                     /translation="MKRNILLNPGPATTTDTVKQAQIVPDICPREQEFVEIMKQIRTDL
                     VKIVH"
     CDS             13035..13961
                     /NRPS_PKS="Domain: Aminotran_5 (5-234). E-value: 7.7e-33.
                     Score: 105.7. Matches aSDomain:
                     nrpspksdomains_ctg18_30_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 66.3; E-value:
                     4.1e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_30"
                     /sec_met_domain="Aminotran_5 (E-value: 5.2e-31, bitscore:
                     99.1, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVCLNSLLPEEKKILVVNNGAYSSRAVEICKYYGLPFIDLKFPI
                     DERPSLEVIERTLKENEDIALVYTTHNETGTGILNPVREIGALVHQYHAVFVVDTTSTY
                     AMRPINIKEDNIDFCMASAQKGLMAMTGVSFVVGKRSIIEQSKDYPKRSYYCNLYLQYD
                     YFEKHGEMHFTPPVQTIYAMRQALKEYFAEGEQEKWKRHTRVFVALHQGLEELGFQDVI
                     KREWQAGLVITVKYPDDPNWSFSAIHDYCYERGFTIYPGKINNTETFRLCALGAVDEAD
                     IQEFFKVFQAGLESMKVAVPVFYREEK"
     aSDomain        13050..13736
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_30_Aminotran_5.1"
                     /evalue="7.70E-33"
                     /label="ctg18_30_Aminotran_5.1"
                     /locus_tag="ctg18_30"
                     /protein_end="234"
                     /protein_start="5"
                     /score="105.7"
                     /tool="antismash"
                     /translation="NSLLPEEKKILVVNNGAYSSRAVEICKYYGLPFIDLKFPIDERPS
                     LEVIERTLKENEDIALVYTTHNETGTGILNPVREIGALVHQYHAVFVVDTTSTYAMRPI
                     NIKEDNIDFCMASAQKGLMAMTGVSFVVGKRSIIEQSKDYPKRSYYCNLYLQYDYFEKH
                     GEMHFTPPVQTIYAMRQALKEYFAEGEQEKWKRHTRVFVALHQGLEELGFQDVIKREWQ
                     AGLVITV"
     CDS             13991..14701
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_31"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.7e-13, bitscore:
                     42.5, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADNEIAILMAAGLGTRMRPLTDKIAKPLVSVHGKSLIETIIEAL
                     QQRGVTIIYVVVGYRKEQFAYLTEKYDHLVLIENKEYLKKNNISSLYAVGDILGSKDCF
                     ICEADLYVTDPAIFLRKFKKSCYFGKMIPGYSDDWVFEMREGKITRVGKGGTDTYNMAG
                     ISYWKKEDAVLIRNAIQEVYKTAGHEQLFWDEIVDQELDNLDVTVEEIPADSVVEIDTF
                     DELCKIDETYRNAE"
     CDS             14716..15849
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 46.3;
                     E-value: 4.3e-14)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_32"
                     /sec_met_domain="TPP_enzyme_N (E-value: 2.3e-19, bitscore:
                     60.9, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.5e-15, bitscore:
                     48.7, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVTDFIKQIKKVGIKTLTGVPDSALRPFCDYINGVGKEEFTHYV
                     PANEGAAVGIAIGEYLSTGVPACVYMQNSGLGNIVNPITSLANEEVYGIPMLLLVGYRG
                     EPGKKDEPQHKYMGKITESLLDVLGIEHMVLGKELTEQEISEGFGRAAQKLKEGQQFAF
                     VLKKDFLEIEEKSIYVNDNSLIREDVIAQIIESLDESDVVVSTTGKISREVYEQSDRIN
                     GSHAQDFLTVGGMGHASMIAFGIAENAKEKRVYCMDGDGAELMHMGSLAFIAKQKPQNF
                     VHICLNNEAHESVGGMPTGCVGLSYAEVARTVGYEAVYYIDTMEELKQVLHDIKPERKL
                     TFIEIKVSMQSRADLGRPKETAAENKENFMKYHGVKE"
     CDS             15846..17141
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 209.5;
                     E-value: 1e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_33"
                     /sec_met_domain="CTP_transf_like (E-value: 4e-16, bitscore:
                     50.8, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 2.6e-118, bitscore:
                     385.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 3.2e-67, bitscore:
                     217.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVYACFCTDVIHEGHLNIIHEAKKYGKVIAGVLSDAAMIRYNR
                     FPTVSFEERKKMLEQIPEVDEVVVQNEVMYGNILEQIKPDYVIHGDNWLNDPMEVIRDN
                     VIENLAKWGGQLIEVPYTYNEQVKNIEAVMRERAAMPEYRRKRLRQLLKLCPIVKTLEV
                     HSGLTGLIAEKTVVANQGEIDQFDAMWLSSLCDSTAKGKPDIELVDMSSRLRTVDDVLE
                     VTTKPIILDGDTGGMIEHFVYNVRTLERIGVSAVIIEDKTGLKKNSLFGTEVEQTQDSI
                     ENFTAKIRAGKHAQRTQDFMIIARIESLILEKGMDDALERASAYVEAGADGIMIHSRKK
                     EPDEIFEFCDKFRNRDAVTPIVVVPTSYNATYESELQAHGVNIVIYANQLTRSAFPAMQ
                     KTATDILTYHRAKEIDDRLMPIKEIITLIDEI"
     CDS             17154..19097
                     /locus_tag="ctg18_34"
                     /transl_table=11
                     /translation="MLVDRLTLQKIDDIGRNIMNDMSIKEQMMQLTKQCILSNDDKAML
                     ECLQIYKSSFGYDDFYITSLSSLRITPEPLVSLIYIKQPDEDEQACCDNINRYNNYQNL
                     EITVLSADNLLEDFYHCFTSMSGQYICFCDCNHKYDSNRIRALLLLLSQNDSVDGVVCS
                     RNFIEADNTILAHPERIYREVLDEHIFGGNQLLTYSIENDVNIYGDLSTLLLSMDYVKT
                     VPFFECDIPDSMQQSALLYQLLYSAKVLYTYMPLVSAILTPALHDAELVHDFQKFLNIF
                     QNQLLEHTSATVNNFSQTENFVPCKKDITFFYTDMGEYYNLKPIADEAEARGYRVSFTR
                     DIFAPAEIGVYCQHVCHPENSRFSVILLHDLAQGRKPNIWEYEPWNKFDIGILPGKFWN
                     NLWSRCAFNYYVNPRCGTYEFGYPKSDLVSSPELAQRVSSLKEKLNLKYDISILYAPSW
                     ENDGKEDDFIKALSSLNVNLLIKQADWSEVYSNITENIRQMRELHEGKYENVYYIEPQE
                     SIMTALAMSDIIVSDESNVMAEALMFGKLSIAVADWLIPDCTPSRYANPMDYVIKTTKK
                     DLRKDVERFLSSPKYYSDFFEKGRELFSNAGNCCVEILDAIGYFTSDKHSTSTAFLKKR
                     MSSKYSICSLWN"
     CDS             19129..20340
                     /locus_tag="ctg18_35"
                     /transl_table=11
                     /translation="MNENKIAFIICTNNQLYFNECCYYINRLLLPEGFERDVIGIEDAP
                     SMCAGYNAGMQSSDAKYKVYLHHDVFIKESKFIFYLLERFCSAPDVGMIGMVGGCGMPK
                     TGVAYLAWNEGTVDCREPDFAYQLICDPAQQADCLVDAVDGLLIATQYDVAWREDLFVN
                     FDFYDVSQSFEMRKAGYHILVPYQKTPWVIHDSSFAKLNHYDENRKIALETYPDFFTEE
                     DGFSFVYEEEWENLSEALADEVRRLIDVGNWEDAGKIIELYHKNQMKNSALELYGVMCE
                     IYEKEQECGIKEHFFDKTGDYEAACQKYITVRFLLRRVECEMESAAYSELKDAVVEGRI
                     SAETLLLMILHGSYDKATVLRKVIPWCEAAGDNDGAQKLQAFYDRVKGKKLPFAYSKRV
                     SVKR"
     CDS             20372..21268
                     /locus_tag="ctg18_36"
                     /transl_table=11
                     /translation="MYKIAIIYAGATYESALNHIRLQELLGKIKVIGIGTQDIYAEYVD
                     GYPVTTIENILQQEWDYLLIAGQEQNFAQMKALLVSIGIEADRIFSIMVFSLPMFDMEE
                     YVQFVNKKVSIISNHCWGGFTYHSLKAEFLSPFINMFIPQADYIRLLESFDAYMNEKVK
                     YYKNEYESNLKREYPVALLGDIELHFNHYKSFEEAEQKWYERKQRMNEERLFVEMQTDS
                     EELAERFDKLPFKQKVVFVPFETKLTSAISLKKINANYSGAFYESVNRLATGQQAFYNI
                     LKLLNGERDFFRVSEKM"
     CDS             21356..21577
                     /locus_tag="ctg18_37"
                     /transl_table=11
                     /translation="MKSGIYVIAEMSANHAGKIENAFKIIEEAAKASADCVKIQTYTAD
                     TLTIDCDDSKYVIIRIYQQLYFSDTLFS"
     CDS             21601..21939
                     /locus_tag="ctg18_38"
                     /transl_table=11
                     /translation="MKTDEKIPLWSERIHEFQFSGQTCKTWCQEHHVPVSSMNYWMRKL
                     KKLDEQSDTDMIFAKMPTEKEISKNETLNISPSPVRIFITNAIRIEVMPECPPEFFRIL
                     IQGLKDHA"
ORIGIN
        1 gagaaagcgt gttctgatcg taaatactgc catgcagatt ccaagaaaag gtgcggcgcc
       61 tttttttgaa atgaaggact ctgtctataa tgcagaatat ctgacgaaaa cagaactgga
      121 atacaagggg gaacactttg cattcctgca gtgtgaggat gacatgccaa accttgatac
      181 cattgtgtcg ctggcaaagc ttgtggtcac gcagaaaccg gaatttttac tcaatattgg
      241 gggaagcgac atctgtgcag acatttgtgg attgtttgtt ccggaaatta cggtaagcac
      301 agtgttttcc aagctgccat tttcctgcgg agaataccag attgttgata aggaactgac
      361 agaagaggat gtggcaattt taagggaact tgaagtgaaa aaagagaatg tgaaacggac
      421 actgtttacg ttcagcttca aggagcagga gcatcatttt acgaaggagc agcttggatt
      481 cagggaggag cagtttgtac ttttgattgt aggatggcgg ctggacgaag aaatttcaga
      541 tgaatttcta cagatgctgg atagtgtctg ccgcaaagat gcacgaatcg tggcagcatt
      601 tatgggaaaa taccaaaact atgaagagag tataaaaaaa tacccgttat tagcagccaa
      661 cagcagatgt ttaggggcac aggaggacgc actggcggtg acggagtgca tggacctgta
      721 tgtgaatcca aagagaaacg gtggcggaag ttccgtggca gaggcgttat acaaagggct
      781 tccagcggtg acactgccag ttggagacgt gtctgcggca gcgggagaat catttagggt
      841 ggcagattat ggcgaaatgg cagagacaat tttgcatttt gcatcggatg aagattatta
      901 tgagaggatg tcccgtctgg cagaagagcg tgcagagcag ctgatggaca gtaagaacag
      961 cttttgcggc gtgatagatg agctggaaca ggatatgaat tagatggagc agcaatggaa
     1021 aatacacatg gattgagatt aaggcgtgca gaaaaggaag actgccgttt cctgtacgaa
     1081 ctgcgtaatg aggaagaggt tcggaaaaat tcatttcaga cagggatatt ttcctacgag
     1141 gatcatgtgg catggtttga gcggaagtta gaagagaaaa atacacggat ctatatctta
     1201 gagcaggatg gagagcgcat cggacaggca cgcgtggatt tggaagggca gaatggagaa
     1261 atttcctatg cactttgtct aagggcaaga ggacacggct attccaaatg gatgttagga
     1321 agcattgaag aggagctgcg cgagcaggca gtctgtcgaa aacttattgc agaggtaaaa
     1381 cgggaaaata tcgcatcaca gaaaatattt gaaacacttt cgtatatagc tgtcccggct
     1441 gattatggat atgtatttga aaaaaagata ccgctgttta ccatcatcat gtgcacttat
     1501 aattctgcac agacgcttgc tacagcggta gagtctgtga gaaaccagga gtttggcggc
     1561 tgggaaatgc agattctaga taacggaagt aaggatgaat ctgtagagaa actgcaggaa
     1621 tatgagaaat cagatgaccg gataaagtgc atctaccgaa aggataacat tggttggggc
     1681 aagggaatca gtgagtgttt gaaaacgtcg gctggaggat atatgatgtt tcttggtgca
     1741 gatgattatc tggcaacgga acatacactt acagaggttg cagatgaggt aaaaaaaaat
     1801 catccacaga ttatttttac gggaacttat tatgcgaaat atgagcaggg ggaatatcac
     1861 ataataagat atacactgcc ggagaataag gtgtacaaag gggacggaga acggctgata
     1921 aggatgacgg agctgatgca caatgtgtat tataattcgg caatgcacta tctgaagatt
     1981 gattttttaa agcagaatgg gatggatttt tacgatccat tttatataga cagccagaca
     2041 atgacagaag cgattgtgaa agcggaaaaa atagttgtca tgagccagcc ggaatatgtg
     2101 ctgacactca atacctcgca gacagcgaaa agaactgtat atgattataa tgtggaacga
     2161 cagtggaaca gtataaaaga aattttgcct ccgaccactg caggcagaga agaagctgtt
     2221 tcctatgtgg cgagacgagt gcttgataac atcgcagcca tgtgccagag catcgtactt
     2281 ggagaagcac tgtgtgaccg tgagatgaat acgattgaga agagtattcc ggagcggttt
     2341 gcgcgtgttg aggaaatgat ttcgacggat gcaatgggcg agatgatgaa ttatgccgga
     2401 cgggaagagt atgcggaatg tctcatcggt gctgcgggag tgacctgctg gatatgtaaa
     2461 aagaataaga gattatcaga cgaaatctgt cataacagta agtggctggc agaatttgtg
     2521 gaagttgcaa tggaagtaga tgagacaacg ggtatggttg tatggaaaaa gcggtttgac
     2581 agagatgcgg gggataggct gttacggatt tttcaaaatt cgtggaatcg ttttaagaca
     2641 ggtgttgagt tagtgttaaa agacgatgtc tggtatgagg atattggaat aagggaaaaa
     2701 ctgtgcgaag aaaaagaaag cggcgtgaca tatgcaagac gcagtataga tcaatagctg
     2761 taaaggaaag aatctgccat ttgcatacat taagcgggtt tctgtaaagc agtgaatgat
     2821 ttgaaaaaaa tgccgatatt atattcagaa aagtgaataa atgcataaag gagcggctat
     2881 gaatttatat gaaaaaatga aatccggcgt ttatgttatt gcggagatgt ctgcaaacca
     2941 tgccggaaag attgaaaatg catttaagat tattgaggaa gctgcaaaag ctggtgctga
     3001 ttgtgtaaag atccagactt atacagcgga cacgctcacg attgactgtg acgacgaacc
     3061 ataccggatc aagggcgggt tatgggacgg atataattac tatcagctat atcaggaagc
     3121 ttatactccg tgggaatggc agcagcagtt aaaggataaa tgcgaagaag taggtgtaga
     3181 tttcctgtcc acaccgtttg accgcactgc ggtagatttc ctggagggga ttggaattga
     3241 attttataag attgcctcgt ttgaactggt agatattccg ttgattgaat atacggcggg
     3301 caagggaaaa ccgatgatca tgtcctgtgg tatggcatcg gaagaagaga ttgcggaagc
     3361 acttgcagca tgcaggcgac agggaaatga acaagtcgta ttgttaaaat gttgcagcca
     3421 gtaccctgca cagtatgagg atatgaatgt gtctgtaatt ccggatatga aggaaaggtt
     3481 tggcgtaccg gttggtctgt ctgatcattc catgggttcc cttgcagacg tggtggcagt
     3541 ttctcttggt gcgcaggtaa ttgaaaaaca tgtgtgctta agtcatgaga ttgagaatcc
     3601 ggatgcagcg ttttcaatgg aaatgaaaga ttttgcccaa atggtacagg atgtccgtaa
     3661 tgcctgcctt atcaagggta gaccgaccta cgaactgacc gagcatgaga aagacagttt
     3721 aaaatacaga cgctcacttg tagcggtaaa accgattgca gaaggagagt tgtttacgga
     3781 agagaatgta agaagtattc gaccggcaat cggaatcaag ccgaaatatt ataaagcatt
     3841 gcttggcaaa ccggcgaaga aggcataccg ttttggggaa ccgattgggc agctggaagt
     3901 ggagcaaata tgatcgtatt tcgggcagac gccaatgaga cggcagcgac gggacatctg
     3961 atgcgctgta tgacaattgc agaagcctgt cgggaaaaag gcgtggaatg tgaattctgg
     4021 cttgcagaag acaaagagac cgaacgactc aggcaggcag gattttctta ccggatctta
     4081 ggaagccaat gggatgatct tgagaaagaa cttccgtttt tagagagaca gcttgatgat
     4141 ttagacaggc aggggaaaaa agttacatat ctggtagcag actcgtatca ggcaactcca
     4201 cgttatcttg gaaaattgaa tgacagaatt ccggtacttt atattgatga tatgagaatg
     4261 cagatatatc cggtggcagc agtgttacaa tatattccgg tcagaacaaa aaattcattg
     4321 aatatagaag aacgatccga gcaaaatatg ccagtctatt tgcgtgggtt taggtatgca
     4381 cctctgcgga aagaatttct aaaatcacat gtggaacaga gagaaaaaag cattctgatt
     4441 acaaccgggg ggactgatac ttataatatt gccggcaggc tgttacagga gtgtctggat
     4501 aaggatgtat ttcaagagta tagatttcat gtgattgttg gaaatatgaa cagtcatgaa
     4561 gcagaactgt gcgggctttc agagagggat aagaggatct gtattcataa aaatatttct
     4621 aatatgagtg attatatgca cagctgtgaa cttgcggttt cggcaagcgg tacaacgtta
     4681 ttggaactgt gtgcctgtgg aataccggcg atatgttttt cttttgcgga taaccagatg
     4741 gcatttgcag ccagtatgga taattacgga gctatgtgct atgtggggga tgcaagggaa
     4801 gaagataaca tagaaagaat tatctgtatg cgacttacag aactggcggg acaggaaaag
     4861 ctgcgaaaaa ggcaggtcgc ctgcatgaag gcacttgtag atggaagagg tgcagaacgg
     4921 attgctgatt tcctgatctg tggaaatttg aacgaatgtg acgatataca taaatagatg
     4981 atgaaagggt gatgattatt atgatacctt atggaagaca gacgattgaa gaggatgata
     5041 ttcagatagt cgtagatgta ctgcgatctg attatctcac aacaggacct aaggtcgcag
     5101 aattcgaaaa acttgtggca gattatgtcg gggcaaaata tgctgtggcg atttcaaatg
     5161 atacagctgc attacatgca gcctgtcatg cggcgggaat cggaccggga gatgaagtga
     5221 tcactacacc gatcacattt gcagcgtcat caaactgtgt attatattgt ggtggtacac
     5281 ctgtattcgc agatgttgat tccaaaactt ataatattga tccggaagat ataaaacgaa
     5341 agatcacggg taagacaaag gcgatcatac cggttcatct tgctggacag ccatgtgata
     5401 tggatgagat ccatgcaatt gcgaaggaac atcatctgat tgttattgag gatgctgcac
     5461 atgcgcttgg ttcggaatat aaaggaaaaa tgattggatc aatgtcagat atgacaacgt
     5521 ttagttttca tccggtaaaa ccgattacaa ccggtgaagg cggtatgatc gtaacgaatg
     5581 atgaaacatt atacaagaaa ctggtattgt tccgcagtca tggaattaca agagatgaaa
     5641 gccagatgac ccgcaatgag ggatcttggt tttatcagca gatcgatctg ggatataatt
     5701 atcgtatgac ggatatccag tgtgcattag gctgtacaca gatgaaaaag ctggatcgtt
     5761 ttattgcacg cagacgtgag attgtagaac gatataatga ggcttttgca gattgcaaaa
     5821 atattgttac tccatatcag cttccagata caaagagcgg ctggcatctt tatattattc
     5881 aggtaaaaaa taaagaccgc aaagaagtat tcgatgcact gcgtgaggag ggaatcggtg
     5941 tgaacgtgca ctatattcct gtttactatc atccgtatta tcaggaacac gggtttaagg
     6001 atgtatattg cccggtagcg gaagagctgt atacacatat tatcagtctg ccgattttcc
     6061 cgaaactgac ggatgagcag caggatgaag tgattgagaa agtgaagaaa gttgcggaaa
     6121 attgatgaat acagggagaa atatgaaatt attatttttt caatggcatt cttttatgaa
     6181 taagggaatc gagcgggggt tgaaggaact ggaaatcccg tatgatacat ttttttatca
     6241 gtttaacgat tgggaaaagg atgatgcttt tttagagcag ttccgggctt atttaaaggc
     6301 gggagcttat acggacgtgc tgtcggtcaa tttttcgcca ttgatttcga tgttgtgtga
     6361 ggaacttgga atcgtatata cggcatgggt atatgattcg ccgcttcaca ttcgaaatct
     6421 ggagagactt aagaattcct gcaaccggat tttctttttt gacaggggac aggcagagga
     6481 acaccgcaaa gatggagtca atgcgatgca tttgccgctt gcggtggata cggaggtctt
     6541 tcgtattaat gcatcgaaac gggaaaaaga agactatcgg acggatatct ctttagttgg
     6601 aaaactttac cagacagagt attcatattt tacggcaccg ttacagggct atataaaggg
     6661 gtatctggaa ggaattgtaa atgcacaggg caaagtgtac ggcggttatt tgataccgga
     6721 attaattacc gatgaactgt tagcacagat gaatgtcgaa tatacaaaag tggcaaagga
     6781 cggctttgtg atgggcagaa gagaacttga atttatgctt gcctgcgaga cgactggaag
     6841 ggaacgttat atggcgttgg cgcttttatc tgcacattat ccggtggatt tgtattcaac
     6901 ggatgtggat aaaaggttag aaaaagtaag atatcgtgga tacgcagact attattcaca
     6961 gatgccgctt gcattttctc agagtaaaat caacctcaat atttcgctca agacaatccg
     7021 taccggaata ccgcttcggg tcattgatgt gcttggatgc ggtggattta tgctctcaaa
     7081 ttatcaggaa gagctctttg agtactttaa cattggagaa gaattagtcg tatatgagaa
     7141 tatagaggac ttgttttata aggcaaaata ttatctcgaa catgaggacg agagaaaaca
     7201 aattgcactt gcgggagttg agcgtgtaaa gcgtgatttt acgttccggg agagattacg
     7261 ggtaatgtat gggaacagta gtgcagacag gagaaactga gatgacaaat gaacagaatg
     7321 agattataac tacaattgaa aaaatgttgg aaatggtgaa aagcggcgaa ttaccattgg
     7381 atatgtgtcc aatatcgaat ttccggacag tatactattg tgcactgtgt tatgcgaatg
     7441 atataaaatt agccgaacag attgcagagg agtattgtac cgtactgcaa tcattagcgg
     7501 caaatggtgc gcggacagaa ttttgcatga tgctggagct tatgattaaa agtatgaagt
     7561 atgaatatga gaagcgcagt tattatgaaa aacaaaataa gatattagcg gataaactgg
     7621 aagaaatgca gaatggaaca tctgtttttg atgagatatt acagtgttat gagaaaaacg
     7681 ggattaatga aaagttcctg gaagatcata cgtaccagtc attagtttcg gtaaaagaaa
     7741 aaggaagtat tgaacttttc aaagagattt ctgctaaagt atatgaaaca gcattaaact
     7801 gtattcgaaa gaaacaggta aaaaaaattg tatttttatt gaaagacagt gcggagtgga
     7861 gctgtgagga attatataag agatttaatg aaacatcggg atatgaagtg tgtgttgcgg
     7921 tagccccttt ttttgcagga tcgcagcagg cagtcagtaa aatgtatctg gatacggttc
     7981 aatattttcg agaaagaaaa attgacacgg ttgagatgta tgatatacag aaaaacaggt
     8041 ataaaagctg ggaagagata gggatgccag acattgtatt tcatttaaat ccacattata
     8101 aggcatttgc agaaagcagc aatatatgca attttccatt gagtatttta aatgtatata
     8161 ttccgtatgg aataatgata tacggaaatg tcagacagca gtataatcag ctatcacata
     8221 tgttatattg gaaaattttc tgtgagacac cgttacataa agaaatggct tcgaaatatg
     8281 cggatatagg agatatcaat gttgtctgca gtggatatgt aaaaatggat actttttttg
     8341 acacctgtct gcaggagaaa agaaaaatat ggaaaatatc tccgagggca gatgaaaaaa
     8401 aaataaagaa aataatatat gcaccgcatt ggtctataaa ggatgctgtt acgggatttg
     8461 gtaattttga taagatatac aaatcgttat atgaatatgt aaagaaaaat gaaacatcaa
     8521 catcgtgggt atttagacca catccgatgc ttagagtagg agcagtacag caagggatat
     8581 ttaaatcgga agaggaatat gaagaatacc ttgaaatgtg gagacagttg ccgaatgccc
     8641 aggtaataga aaatggaatg tatacagata tttttgaatc gtcagatgcg atgattttag
     8701 atagtatatc atttttggga gaatatatct atatgcataa accaatgctt tttcttacaa
     8761 gggatagaaa cactttcaat gattttggaa aagaattggt aagggtgcta tacaaaacag
     8821 atggaggaaa tctggaagga ataaagaatt ttgttgaaaa aaatgtaatt gggaatgaag
     8881 atccaatgaa agaacggcgt gaagaatttt ttgaaaaata tatggactat agaaatcaaa
     8941 atggaatgct ggcaagtgaa tatataaaac agtatattga ctgtttaaca gaaggtgata
     9001 aagagtaatg aatctaacag aacggtatag taaaaaactt gaaacaactg taaatggtcg
     9061 gcagatatca ttggatggtg tattgttaca attggaagtg acaaatgcct gcaaccataa
     9121 atgtatgttt tgtcctaatg tagagagtca tcgtcctaaa aaaatgatag actttgaatt
     9181 ggcaaagaga gtgatgaaag agtgtgccga ttttttagga gcagataaaa ggatttgttt
     9241 tcatatgaat ggagaaccct tattatataa aaggcttcct gaactggtgg aatattctaa
     9301 aaaattagga tatgagtatt cgtttattac aaccaatggt tcgctggcaa atgaggaatt
     9361 gttgacaaga ttatttgaag caggattaga tagtataaaa ttttccatta atgctggaag
     9421 tagagaaaca tataagaaaa tacatggtgt tgataattat gagaatgcaa taaatgcgtt
     9481 aaaattttcg tggaaatatc gtgaagaaaa tgggaaaaag tataagatat tcgtttcgtg
     9541 tgtaggaata aaacaaaatt atgaggaatt agaggcattt aatcagatgg ccagctgtta
     9601 ctgtgatgaa gttgtatttt attatccttg tggatatgca ggacaaaaat tagccagttt
     9661 ggaagacaga tgtgatttgt caaaattatc tgttaaatca tttgaaataa ggcatacagt
     9721 tccatgtgct gtgttatgga attctattaa tgtgacatgt gaaggatatc tatctttatg
     9781 ctgcagtgaa tcagataatc ggcttattgt agaggatatt aatcatatag gggttaaaga
     9841 agcctggctg ggagaaaaga tgatgactat tcgggaaaag catgccaaaa tgaatataga
     9901 agagatgccg tgtctgtcct gtgttacaga aacgccatat gacattacaa agattgataa
     9961 acatttattt gcgctatcac tacaaaatac taaagaaatg ctatgatgtg ataaatatca
    10021 ggataatgtt gggagagaat aatgcgaata aaagaaaaaa ttgaaaatat cgattacaat
    10081 gatacaaaac tcttttttaa gaaacgtgca gagaaatttc aggaaagtaa tccatattcg
    10141 gttaccatgt atcaggataa taatgaagaa atagtaagac agcggaataa aaaagagata
    10201 gaaaaactga tgccattgtt acatatggaa aaagaggcaa aggtactaga tgttgcatgc
    10261 ggaattggaa gatgggcaga tgctttgcca gaagatatta aagagtattg tggtatggat
    10321 tttagtgaag aattggtagc aattgcgaat aaaagaaatc atagaaacag atttttttac
    10381 tgtgtaggtg gtgccaatga aattgcagcg gtactgaaaa aaaatggaaa gggtttgtat
    10441 aacaggattt tgatcgttgg aattttaatg tatttgaatg atgtagatat ggcagattca
    10501 ttaagacaga tagaaaaagt ttgtgagaca aaatccgtta tatgtatccg ggaacctatt
    10561 gcaatagaag aaaggctcac attaaaagat tttttttctg aggaattgaa cgattattat
    10621 aatgctatat atagaacacg ggatgaattg atggtaagta taaatgaaat gttcttaaat
    10681 aaaggattca ggataaaaga ggaaggattt ttatttgatg acgatgcgct taacaataga
    10741 aaagagaccg ctcaatatta ctatatcttg gaaaggtgac caaacatgta tagggaaaag
    10801 gtagggatta taggtggctt tggggcatat gcaacgttaa atttttataa aagattgttg
    10861 gaagaattcg cttcagaaag tgaacgaaat tatcctcata taataatgga taataatttt
    10921 accatgccaa gcaggacaag ggcattattg tatggtgagg catatgatga ggtggtggat
    10981 ggtatttctg attccataca gttaatgatg cagaatgatg tgagcaagat catattagcg
    11041 tgtggaacag cgcattattt tttaaatgat gtatataaaa aaattccgga ggcaaaagaa
    11101 aaaattgtag acattattaa tattatgggc gaagaactga aattgaagga tgagggagaa
    11161 gtgttggtta ttgctgcgga gggggcgtta cagaaaaaat tatatcaaac acgtttaaaa
    11221 aagtatggaa taaaatgtgt aaatccagat gaagaggatt ttatagatat tcggtatttc
    11281 attgaatgtg tgaaaagaaa tgaattgaat gaagatttag tgcatcagtt tggaaatttt
    11341 cttgacaaat ttggcaaaag aaatgtggtt ttagggtgta cagaatttcc agtcctggta
    11401 gaatatattg ataaatgcca aaaacagaga gtacagtaaa tttacgaaaa caatattgct
    11461 tttacgatcc actacagatg acgataaagt ggttgaaaga aaatttacaa tagcaaaaga
    11521 gaggtagagg atgagcagat atatttttct attcgatttg gattcaacgg taaccaaaca
    11581 ggaaatattg cctactattt caaaaaggct aggaatatat gagaggatga gcgaacttac
    11641 agagagtaca atgagggggg aaataccgtt taaacagagt tttttgcaaa gggttgaact
    11701 attgaaagat gttcctgtaa gtgaagtgaa tgaaatggtc agcagaattc aattaaacaa
    11761 tcatttagtg gattttatac agaaaaatca cgatagatgc catattgtta cagggaattt
    11821 ggatgtatgg attgatgggg tgatcaggaa gttgggaatg gaacgaaata cgttttgttc
    11881 taaagcgatt gtgaaaaatg attatattga agacgtgttt aatattgtag acaaaaatgc
    11941 ggttattggt caaatggttt taccatttgt tgcaattgga gatggaaata atgatgctga
    12001 gatgatagag gcagcggaag taggaattgg gtatggtggg gtaagggaga ttgcaccggc
    12061 agtacttgca tgtgccagtc atgcaattta tgatgaggaa aaattagtcg aatttttaga
    12121 aaggctcttg taaaggagga aatgcaatgc aggtttcgag gacagtaatc attagctgcg
    12181 caggcatggg gaatcgtttg gggcttggaa ctacaaaagc actggttgaa gtagaaggta
    12241 aaccgttaat tatgcatcat cttgaaaagc tgaaagatga gagtgatatt cgtgtagtag
    12301 ttggttatca ggcagaaaag gtaattaatg tagttagaaa atatcgaaaa gatgttgtgt
    12361 ttgtatttaa ccataattat agagaaacag gaacaggtgc aagtgttgcg ttagcatcac
    12421 aatatgcaaa tgagtatatt ttatctttgg atggagattt aataatacat cctgatgata
    12481 tgaaaaaaat attggaatgt gatcatgaat ttgtgagtgg aggaataccg gatacagatg
    12541 agccgtggat gcttcagaca tacaaagatg atggtaaaga gtttgtaagt gcattttcaa
    12601 agaatattgg caattatgaa tggaatggca ttacacaaat gaagagcgca aagatcaaaa
    12661 atggacaagg acatgttttt cagttaatag aaccatattt gccaattccg tttttggaac
    12721 ttagaacacg cgaaattgat acggtaaatg attatgaaag agcggttgag tgggttagaa
    12781 ataatttcag ggaataagat gtatgcaacg tatttgaagg agaaaacaac gtgaaaagaa
    12841 atatattatt aaatccggga cccgccacaa ccactgacac ggtaaaacag gcacagatag
    12901 tgccggatat ttgtccgcgg gaacaggaat ttgttgagat aatgaaacag atccgcacag
    12961 atctggtcaa aatcgtacat tgagatttag aggaatatac atctgtatta ttctgcggtt
    13021 cgggaacgat ttccatggat gtatgtttaa attcgctgtt gccggaggaa aagaaaatac
    13081 tggtggtcaa taacggtgca tacagttcaa gagcggtcga gatctgtaaa tattacggac
    13141 tgccgtttat tgatctgaaa tttccgattg atgagagacc atcgttggaa gtaattgagc
    13201 gtacattaaa agaaaacgag gatattgccc ttgtctatac gacgcacaat gagacaggta
    13261 cgggaattct gaatccggta cgggagattg gggcgctggt gcatcagtat catgcagtat
    13321 ttgtggtaga tacaacatcc acctatgcga tgcgtccgat caatatcaaa gaagataata
    13381 ttgatttttg tatggcatcc gcacagaaag gtcttatggc aatgacagga gtatcttttg
    13441 ttgtcggcaa aagaagtatt attgaacagt caaaggatta tccaaagaga tcttattatt
    13501 gcaatttata tctgcaatat gattatttcg aaaaacatgg agaaatgcac tttaccccac
    13561 cggtacagac tatttacgcg atgcggcagg cactaaagga atattttgca gagggtgagc
    13621 aggaaaagtg gaaacgtcat accagagttt ttgtggcctt acatcaggga ttggaagagc
    13681 tgggatttca ggatgtgata aagcgggaat ggcaggcagg actggtcatt actgtaaaat
    13741 acccagatga tccaaactgg agtttttctg caatccatga ttattgctat gagagaggat
    13801 ttacgatata tcctggaaaa atcaacaata cggaaacctt ccggctttgt gcgttaggtg
    13861 ctgttgatga agctgatatc caggagtttt ttaaagtatt tcaagcagga ttggaaagca
    13921 tgaaagtggc ggttcctgtt ttttaccgtg aagaaaaata aaaggatcag attatgaggt
    13981 gatatgcaat atggcagata acgagattgc tattttaatg gcagcgggac ttgggacaag
    14041 aatgagacct ctgacagata aaattgccaa gccattggta agtgttcatg ggaaatcact
    14101 gattgaaaca attattgaag cgttgcagca gcgtggtgtc acaataattt atgttgttgt
    14161 aggatatcgg aaagagcagt ttgcttattt aacagaaaaa tatgatcatt tggtattgat
    14221 tgaaaataag gagtatctga aaaaaaataa tatttcatca ctgtatgctg tgggggatat
    14281 tctgggaagt aaggactgtt ttatttgcga ggcagatctg tatgtgacgg atcctgcaat
    14341 ttttctgagg aaatttaaga aatcctgcta ttttggaaaa atgattccgg gatattcgga
    14401 tgactgggta tttgaaatgc gggaaggaaa aattaccaga gtcggaaaag gcggcacgga
    14461 tacttataat atggcaggaa tctcgtattg gaaaaaggaa gatgccgtgt taatcaggaa
    14521 tgccattcaa gaagtatata aaacagcagg acatgaacag cttttctggg atgagatcgt
    14581 ggatcaggaa ttggacaatc ttgatgttac ggtagaagag ataccggcag atagtgtggt
    14641 tgagattgat acatttgacg aattatgtaa aatagatgag acataccgta atgcagaata
    14701 gatgggagaa gagaaatgat tgtaacggat tttataaaac agatcaaaaa agtgggaatt
    14761 aaaacattga caggtgtacc ggattctgca ctaaggccat tctgcgatta tatcaatgga
    14821 gtggggaaag aggaatttac acattatgta ccggcaaatg aaggggcagc agtcggtatt
    14881 gcaatcggag aatatctttc gacgggcgta cctgcctgtg tatacatgca gaacagtgga
    14941 cttggaaata ttgttaatcc gatcacatcg cttgcaaatg aggaagtata cggaatcccg
    15001 atgctgttat tggttgggta ccgcggtgag ccgggcaaaa aggatgaacc acagcacaaa
    15061 tatatgggta agatcacaga aagcctgctg gatgtgcttg gcatagaaca tatggtgctt
    15121 gggaaagaac tcacggagca ggagatttca gagggctttg ggagagctgc acaaaagtta
    15181 aaggaagggc agcagtttgc gtttgtcctg aagaaggatt tccttgagat tgaagaaaaa
    15241 agtatttatg taaatgacaa ttcactgatc cgggaagatg ttattgcaca gattatagag
    15301 tcactggatg aaagcgatgt tgtggtttct acgactggaa agatatccag ggaggtatat
    15361 gaacagagtg acagaatcaa cggaagccat gcgcaggatt tcctgaccgt aggcgggatg
    15421 ggacacgcat ccatgatcgc atttggaatt gcggagaatg caaaagaaaa acgggtgtac
    15481 tgcatggatg gtgacggagc agaactgatg catatgggaa gtctggcatt tattgcaaag
    15541 cagaaaccgc aaaattttgt ccatatctgt ctgaacaatg aggcacatga atcggttgga
    15601 ggaatgccga ccggatgcgt agggttgagt tacgcagaag ttgcgcggac agttgggtac
    15661 gaagctgttt actacattga tacaatggaa gaactaaagc aggttttgca tgacattaaa
    15721 ccagaaagaa aacttacttt cattgagata aaggtttcca tgcagtcaag agcggatctg
    15781 ggaagaccaa aagaaacagc agcagaaaac aaagagaatt ttatgaaata ccacggagtg
    15841 aaagaatgaa aaaagtatat gcatgttttt gtacagacgt gatccacgag ggtcatctga
    15901 atattattca tgaagcaaaa aaatatggaa aagtaattgc gggtgtatta agcgatgctg
    15961 cgatgatacg ttataaccgt tttcctactg tttcatttga agagcggaaa aagatgttag
    16021 agcagattcc tgaggtggat gaagtagtag tacagaatga ggtcatgtac gggaatattt
    16081 tagagcagat aaagccggat tatgtcattc atggggataa ctggctgaat gatccgatgg
    16141 aagtgatccg cgataatgta atcgaaaatc tggcaaaatg gggtggccaa ttaatcgaag
    16201 ttccatatac atataatgag caggtaaaaa atatagaggc agtgatgcgg gagcgcgctg
    16261 ccatgcccga atatcgcaga aaacggctgc gccagttact taaattatgt cctatcgtaa
    16321 agactttgga agtgcatagt gggctgactg gtcttatagc cgaaaaaacg gttgtggcaa
    16381 accaggggga gatcgatcag tttgatgcaa tgtggctttc aagtctgtgt gattccactg
    16441 cgaaaggaaa accggatatt gaactggtag atatgtcgtc aagactgcgt accgtagatg
    16501 atgtacttga ggtgacgaca aagccgatca ttttagatgg tgataccggc ggaatgatcg
    16561 aacattttgt atacaatgtg cgtacattgg aacgcatcgg cgtctctgcc gtgatcatcg
    16621 aagataagac aggattaaag aaaaattctt tgtttgggac agaggtagag cagacgcagg
    16681 acagcatcga gaactttact gccaagatcc gcgcaggaaa gcatgcacag cgcacacagg
    16741 attttatgat tattgcccgc attgagagcc tgattctaga aaagggtatg gatgacgcct
    16801 tagagagggc atctgcctat gtggaagcag gtgcagatgg aatcatgatc cacagcagga
    16861 aaaaagaacc ggatgaaatc tttgaatttt gtgataagtt tcgtaatagg gatgcggtaa
    16921 caccgatcgt tgttgtgcca acctcatata atgccaccta tgagagtgag ttgcaggcac
    16981 atggggtcaa cattgtgatt tatgcaaatc agcttacgcg cagtgcgttt ccagcaatgc
    17041 agaaaacagc tacagatatt ctgacatatc acagagcgaa agaaatcgat gacagattga
    17101 tgccaattaa ggagattatt actttgattg atgagattta ggtattgtag aatatgcttg
    17161 tggacagact gacattacag aaaattgacg atatagggag aaatattatg aacgatatgt
    17221 ctattaaaga acaaatgatg cagttaacaa aacaatgtat tttatctaac gatgataaag
    17281 ctatgcttga atgtctgcaa atttacaaat catcttttgg ctatgatgat ttttatatta
    17341 ctagtttatc ttctttgcgt attacaccag agccattggt aagccttatt tacataaaac
    17401 agccggatga ggatgaacaa gcatgttgtg ataatatcaa cagatacaat aattatcaaa
    17461 atcttgaaat tacagttctg tctgcagata atttgctgga agatttttat cattgtttta
    17521 ccagtatgtc aggtcaatat atctgctttt gcgactgtaa ccacaaatat gacagcaacc
    17581 gtattcgggc tttgctttta ctacttagcc agaatgattc tgttgatgga gtcgtttgca
    17641 gtcgaaattt tattgaggca gataatacaa tccttgcaca tcctgagcga atttaccggg
    17701 aagtacttga tgaacatatt tttggtggaa atcagttatt aacttatagc attgaaaatg
    17761 atgtaaatat atatggcgat ttatctaccc tgttattatc catggattat gtaaaaaccg
    17821 tgcctttttt tgaatgtgat attcctgatt caatgcagca atcagcgttg ctgtatcagt
    17881 tactttattc ggctaaagtt ttatatacct atatgccatt agtatctgct atactgacac
    17941 ccgctttgca cgatgccgaa ttagttcatg attttcaaaa atttttaaat atctttcaaa
    18001 atcagttact ggaacataca tcagcaacag tgaataattt tagccagaca gaaaattttg
    18061 tcccatgtaa aaaggatatt acattttttt ataccgatat gggtgaatat tataatttaa
    18121 aaccgattgc agatgaggct gaagcccggg gatatagagt gtcttttacc agggatatct
    18181 ttgcaccggc agaaattggt gtttattgtc agcatgtatg tcatcctgaa aattcaagat
    18241 tttctgtgat tcttctgcat gatctggcac agggacgtaa accaaacatc tgggagtatg
    18301 agccttggaa taagtttgac attgggattc ttccaggaaa attctggaat aatctgtgga
    18361 gcagatgcgc ctttaattat tatgtcaatc caagatgtgg aacatatgaa tttggttatc
    18421 ctaaaagtga tttggtatcg tctcctgaac ttgcacagcg tgttagcagt ttgaaagaaa
    18481 agttaaattt aaagtatgat atttcgatac tttatgcacc atcatgggag aatgacggaa
    18541 aagaggatga ctttattaag gcattgtctt ctttaaatgt gaatttgctt atcaagcagg
    18601 ccgactggtc agaggtgtat tctaatatta ctgagaatat acggcaaatg cgagaacttc
    18661 atgagggtaa atatgaaaat gtatattaca ttgagccgca ggaaagtatc atgacagcac
    18721 ttgcaatgag cgacattatt gtttctgatg aatccaatgt tatggcggaa gcattaatgt
    18781 ttggtaagtt aagtattgcg gttgctgatt ggcttattcc cgattgtacg ccaagcagat
    18841 atgcgaatcc gatggattat gttattaaaa caacaaaaaa agatttaaga aaagatgttg
    18901 aaaggttttt gtcatctccc aagtattatt ctgatttttt tgaaaaggga agagaacttt
    18961 tttcaaatgc aggaaactgc tgtgtagaaa ttttggatgc gattgggtat tttacatctg
    19021 ataaacacag tacatcgact gcttttttga aaaaaagaat gtcatcaaag tattctatct
    19081 gcagtctgtg gaattagtga tagtggagat aagagtggag aagaatacat gaatgaaaat
    19141 aaaatcgcat ttatcatatg cacgaacaat caattatatt ttaatgagtg ctgctactac
    19201 ataaacaggc tgcttctgcc ggaaggattc gagcgggatg tcatcggcat tgaggatgca
    19261 ccatcgatgt gtgcaggata caatgccggg atgcagagca gtgacgctaa atataaagta
    19321 tatctgcacc atgatgtgtt tatcaaagaa tcgaagttta ttttttatct gttagagcgg
    19381 ttttgtagtg caccggatgt cggcatgatt ggaatggtcg gcggatgcgg gatgcccaaa
    19441 accggagttg cttaccttgc gtggaatgag ggcactgtgg attgcaggga gccggatttt
    19501 gcatatcagc tcatctgcga cccggcacag caggcagact gtctggtgga tgcggtggac
    19561 ggacttttga tcgcgacaca gtatgatgtg gcatggcggg aagatttatt tgtgaacttt
    19621 gatttttatg atgtatcgca gtcctttgag atgcgtaaag caggatatca tatcttggtt
    19681 ccttatcaga agacaccgtg ggtgattcac gacagtagtt ttgcaaagtt gaatcattat
    19741 gatgagaatc gaaaaattgc acttgaaacg tatccggatt tttttacgga ggaggatgga
    19801 ttttcattcg tctatgagga ggaatgggag aatctaagcg aggcgctggc agatgaggtg
    19861 cgcagactaa ttgatgtggg gaattgggaa gatgctggaa aaatcataga gttgtatcac
    19921 aaaaaccaga tgaaaaattc tgcgttagaa ctgtatggtg taatgtgtga aatctatgaa
    19981 aaagagcagg agtgtggtat aaaagaacac ttttttgata agacaggtga ctatgaggca
    20041 gcctgccaga aatacataac cgtaagattt cttttgcgcc gggtagagtg cgaaatggag
    20101 agtgcggctt attcagagtt aaaggatgca gtggtggaag gaagaatttc tgcggagaca
    20161 cttcttttaa tgattttgca cggaagctat gataaggcga cagtgcttcg aaaagtcatc
    20221 ccatggtgtg aagcagcggg agataatgac ggtgcacaga aactgcaggc attctatgac
    20281 agggtaaaag gaaagaagct gccatttgca tacagtaagc gggtttctgt aaaacggtga
    20341 agaaaatata caatgttcga agagagaaaa aatgtataag attgcaatta tttatgcagg
    20401 tgcaacatac gagagtgcgt taaatcatat aagacttcag gaattgctcg gaaagataaa
    20461 agttattgga atcggaacgc aggatatcta tgcggagtat gtagatgggt atccagtgac
    20521 taccatcgaa aatattttgc aacaggagtg ggattatctt ttgattgcag gtcaggaaca
    20581 gaattttgca caaatgaagg cattgttggt aagtatcgga atagaggcgg acagaatttt
    20641 ttcgataatg gtattttcgc tgccaatgtt tgacatggaa gaatatgtgc agtttgttaa
    20701 caaaaaggta agcatcatat caaatcattg ctggggtggt tttacttatc attcgctgaa
    20761 agcagaattt ttgtccccat ttattaatat gtttattcca caagcagatt acatcagact
    20821 gttagaaagt tttgatgctt atatgaatga aaaagtaaaa tattataaaa atgaatatga
    20881 gtcaaattta aaaagagaat atccagtggc attacttggt gacatagagc ttcatttcaa
    20941 tcactataaa tcttttgaag aggcagaaca aaaatggtat gaaagaaaac aacggatgaa
    21001 tgaggaaagg ttgtttgttg aaatgcagac ggatagtgaa gaactggcag aacgatttga
    21061 taagttgccg tttaaacaaa aagtggtatt cgttccgttt gaaacaaagc ttacatcagc
    21121 aataagttta aagaaaatca atgcaaacta ttcgggtgca ttttatgaga gtgtaaatag
    21181 gttggcaaca ggacagcagg cattttacaa tattctgaag ttgttaaatg gagaaagaga
    21241 tttctttagg gttagtgaaa aaatgtaagc agtgaatgat ttgaaaaaat gccgatatta
    21301 tattcagaaa agtgaataaa tgcataaagg agcagctatg aatttatatg aataaatgaa
    21361 atccggcatt tatgttattg cggagatgtc tgcaaaccat gcgggaaaga ttgaaaatgc
    21421 atttaagatt attgaggaag ctgcaaaagc tagtgctgat tgtgtaaaga tccagactta
    21481 tacagcggac acgctcacga ttgactgtga tgacagtaag tacgtaatca tccgtatcta
    21541 tcagcaacta tatttttctg atacactctt ttcataacaa agaaaggaaa ctgtatcatt
    21601 atgaaaacag atgaaaaaat cccactgtgg tctgaaagaa tccatgaatt tcaattcagt
    21661 gggcagactt gcaaaacatg gtgtcaggaa catcacgttc cagtctcttc aatgaattat
    21721 tggatgcgca agctgaaaaa attggacgaa caatcagata cagatatgat ttttgcaaaa
    21781 atgccaacgg aaaaagaaat ttcaaagaat gagactttga atatcagccc atctccagtc
    21841 cgcattttta tcacaaacgc tattcggatt gaagtgatgc ctgaatgccc gccggaattt
    21901 tttcgtattc tgatccaggg gctgaaagat catgcttgat ctggcaggtg gcacaaccgt
    21961 ttaccttgcc tgtggagcta ccgatctgag aaaaagctat cacggactgg ctgcaattat
    22021 caagctaaaa ttcaaacttg atccctattc gcgctgcatg tttgcgnnnn nnnnnnaaaa
    22081 ttcaaacttg atccctattc gcgctgcatg tttgcgcgct gcatgtttgc gttctgcaac
    22141 c
//
