Select genomic region:
Overview
1.1
6.1
12.1
23.1
45.1
45.2
55.1

### Identified primary metabolite regions

c00001_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_1)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 1.1 | Rnf_complex,succinate2propionate | SCFA | 250,695 | 295,183 | Rnf complex C. sporogenes | RNF | 100%

c00006_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_6)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 6.1 | porA | SCFA | 89,657 | 113,126 |

c00012_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_12)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 12.1 | gallic_acid_met | Aromatic | 77,688 | 99,716 | Gallic acid degradation B. sp. KLE | GALL | 100%

c00023_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_23)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 23.1 | Pyruvate2acetate-formate | SCFA | 243,895 | 266,889 | Pyruvate to acetate and formate C. acetobutylicum | PFL_acetate | 100%

c00045_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_45)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 45.1 | Others_HGD_unassigned | Putative | 15,879 | 40,135 |
Region 45.2 | Putrescine2spermidine | Aliphatic_amine | 90,769 | 114,211 | Putrescine2spermidine E. rectale | SPRM | 100%

c00055_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_60)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 55.1 | acetate2butyrate | SCFA | 116,197 | 141,440 | Acetate to butyrate C. sporogenes | BUT | 83%

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 1.1 | Rnf_complex,succinate2propionate | SCFA | 250,695 | 295,183 | Rnf complex C. sporogenes | RNF | 100%
Region 6.1 | porA | SCFA | 89,657 | 113,126 |
Region 12.1 | gallic_acid_met | Aromatic | 77,688 | 99,716 | Gallic acid degradation B. sp. KLE | GALL | 100%
Region 23.1 | Pyruvate2acetate-formate | SCFA | 243,895 | 266,889 | Pyruvate to acetate and formate C. acetobutylicum | PFL_acetate | 100%
Region 45.1 | Others_HGD_unassigned | Putative | 15,879 | 40,135 |
Region 45.2 | Putrescine2spermidine | Aliphatic_amine | 90,769 | 114,211 | Putrescine2spermidine E. rectale | SPRM | 100%
Region 55.1 | acetate2butyrate | SCFA | 116,197 | 141,440 | Acetate to butyrate C. sporogenes | BUT | 83%

No primary metabolite regions were found in these records:
  c00002_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_2)
  c00003_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_3)
  c00004_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_4)
  c00005_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_5)
  c00007_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_7)
  c00008_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_8)
  c00009_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_9)
  c00010_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_10)
  c00011_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_11)
  c00013_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_13)
  c00014_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_14)
  c00015_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_15)
  c00016_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_16)
  c00017_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_17)
  c00018_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_18)
  c00019_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_19)
  c00020_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_20)
  c00021_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_21)
  c00022_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_22)
  c00024_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_24)
  c00025_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_25)
  c00026_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_26)
  c00027_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_27)
  c00028_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_28)
  c00029_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_29)
  c00030_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_30)
  c00031_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_31)
  c00032_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_32)
  c00033_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_33)
  c00034_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_34)
  c00035_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_35)
  c00036_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_36)
  c00037_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_37)
  c00038_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_38)
  c00039_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_39)
  c00040_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_40)
  c00041_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_41)
  c00042_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_42)
  c00043_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_43)
  c00044_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_44)
  c00046_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_46)
  c00047_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_47)
  c00048_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_48)
  c00049_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_49)
  c00050_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_50)
  c00051_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_51)
  c00052_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_56)
  c00053_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_58)
  c00054_gnlPro.. (original name was: gnl|Prokka|JEMIGLEB_59)

Compact view
c00001_gnlPro.. - Region 1 - Rnf_complex,succinate2propionate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 250,695 - 295,183 nt. (total: 44,489 nt) Show pHMM detection rules used
Rnf_complex: (Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))
succinate2propionate: (minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not Cytidylate_kin)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00006_gnlPro.. - Region 1 - porA
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 89,657 - 113,126 nt. (total: 23,470 nt) Show pHMM detection rules used
porA: (Fer4_7 and TPP_enzyme_C and POR and POR_N and PFOR_II and not (EKR or Fer4_16))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00012_gnlPro.. - Region 1 - gallic_acid_met
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 77,688 - 99,716 nt. (total: 22,029 nt) Show pHMM detection rules used
gallic_acid_met: (minimum(1, [Flavoprotein, Semialdhyde_dh]) and gallic_acid)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00023_gnlPro.. - Region 1 - Pyruvate2acetate-formate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 243,895 - 266,889 nt. (total: 22,995 nt) Show pHMM detection rules used
Pyruvate2acetate-formate: ((PFL_acetate1 or PFL_acetate2) and Radical_SAM)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00045_gnlPro.. - Region 1 - Others_HGD_unassigned
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 15,879 - 40,135 nt. (total: 24,257 nt) Show pHMM detection rules used
Others_HGD_unassigned: (minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl, Carboxyl_trans, CoA_trans, CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans, CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III, ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C, BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C, Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00045_gnlPro.. - Region 2 - Putrescine2spermidine
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 90,769 - 114,211 nt. (total: 23,443 nt) Show pHMM detection rules used
Putrescine2spermidine: (minimum(2, [AdoMet_dc, Spermine_synt_N, Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00055_gnlPro.. - Region 1 - acetate2butyrate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 116,197 - 141,440 nt. (total: 25,244 nt) Show pHMM detection rules used
acetate2butyrate: (not (POR or POR_N or PFOR_II) and minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF, ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1, ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4, Thiolase_C]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.