LOCUS       c00026_gnlPro..        14858 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BFHIEPOD_36.
ACCESSION   c00026_gnlPro..
VERSION     c00026_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 23:02:40
            Original ID  :: gnl|Prokka|BFHIEPOD_36
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14858
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14858
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1418:4858]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1419..4858
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14858
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14858
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             3..98
                     /locus_tag="ctg26_1"
                     /transl_table=11
                     /translation="TPGSYALIDPGVGGGYMGVLGKFYYVFFIDL"
     CDS             complement(434..1159)
                     /locus_tag="ctg26_2"
                     /transl_table=11
                     /translation="MKTAIFSIGVFLISLFLGSCQPSETSCSVVDTGKTLDYKIGDKLL
                     FSYNYTTVYPAPGVDSVYKRSGFIHPLKTLGGEVMTNCSPADHYHHFGLWYAWTKTTFE
                     GNEIDFWNLHKKQGTVRFRNFEHVSDNGFVATLDHVVYPDSPAEKVAMNERLEINIGTT
                     SLPGYYIDYHTTIRLASPARSPWKLTVMAAYASVRAKTGTIRQPKCSPRKAFPATKLTV
                     REPVGATTKGKPETKRPVS"
     CDS             1419..2093
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_3"
                     /sec_met_domain="SucD_FumR (E-value: 1.7e-66, bitscore:
                     217.4, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLILFLVFHLCMNIAAVFSGEAYNVI
                     CGLLGSNWYALLGTLVLAAGVVVHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGVIVILFMVLHFTQFWYNMMFAELAGIHGDIHPQDGAAFINFYFQGNVVNTVLYL
                     IWFVALWFHLTHGFWSAIHTIGWNNTVWLSRWECISKWVATIICGLFAVITVIFYLNGV
                     GA"
     CDS             2132..4075
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.4; E-value:
                     1.1e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_4"
                     /sec_met_domain="FAD_binding_2 (E-value: 4.1e-59, bitscore:
                     194.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 2.6e-37,
                     bitscore: 121.5, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERFAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDFQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFVEAEKAINARIAKLMNVKGKETVDSIHRKLGHI
                     MWEHVGMARDAEGLKEAIQMLKDLKKEFWSNVFIPGEANSLNVELDKALRLADFIEIGA
                     LMAHDALDRAESCGGHFRTEHQTEEGEAMRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     QFVVPQTRNYKK"
     CDS             4103..4858
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_5"
                     /sec_met_domain="Fer2_3 (E-value: 1.7e-25, bitscore: 83.0,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 4.9e-11, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5.2e-05, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKGPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANAIPISKADADLAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFISAKLQD"
     CDS             5049..5207
                     /locus_tag="ctg26_6"
                     /transl_table=11
                     /translation="MKKTHCKYKVYLLNTQEFVITFYCKFATFCFKIDTVCGFTLLLYQ
                     QSIDSDT"
     CDS             complement(5180..6211)
                     /locus_tag="ctg26_7"
                     /transl_table=11
                     /translation="MKIGTIDLGERPVFLAPMEDVTDISFRLMCKRFGADMVYTEFVSA
                     DALIRSVNKTQQKLNVADEERPVAIQIYGRDVPTMVEAAQICEAAHPDILDINFGCPVK
                     RVAGKGAGAGMLRNIPLMLDITREVVKAVNIPVTVKTRLGWDADNRIIVDLAEQLQDCG
                     IAALSIHGRTRAQMYTGEADWTLIGEVKNNPRIQIPIIGNGDVTSAEICKQRFEQYGVD
                     AVMIGRGSIGRPWIFREVRHYLDTGETLPAESFSWYLDILKKQVEQSVERLDERRGILH
                     IRRHLAATPLFKGIADFKQTRVAMLRAETVEALFDILDSIPDKFHTGYGFQSDSQVSES
                     IDC"
     CDS             6371..6727
                     /locus_tag="ctg26_8"
                     /transl_table=11
                     /translation="MVRLTSKEEEILGYFWAKGPLFVRELLDLQEESKPHYNTLSTIVR
                     SLEEKGYIGYKVYGNTHQYYALVSEDEYRRNSLKQVISKYYDNSYTRVVSTLIEEEVLT
                     IDELQKLIQQIKNK"
     CDS             6741..7373
                     /locus_tag="ctg26_9"
                     /transl_table=11
                     /translation="MDAFLLYILKSGICLTVFYVCFKALFSNDTFFRFNRWILLVGTGV
                     CMLLPLCRIQTARPFPLSRPVSQLEIVFYEEEMKAFPVPESKEEITIPTEQRNISVPWT
                     GIIGIAFLTGSGICLTTTILSFGKMYQLTRKNRKLKQGKYTLILTPDPVSPFSWGRYIF
                     LSENDYRNHPNEILMHEKMHLRYNHSVDLIYMKRFFFCNGLILPYGY"
     CDS             7541..8509
                     /locus_tag="ctg26_10"
                     /transl_table=11
                     /translation="MMLKKKSNNWARLKLALLVPVGFAALSAFARPETSPPPAATMTDN
                     IHLSINKSTVNQETMQQDHAVFLTYKESGSEDLNSIVCKTLDRIRTRVAEGQFKNALEV
                     TVNPAFDDIPASYLETVKDVLEERDIKCKIDMTVPNTIMDDVAKPYRKYDDVVYLIQNK
                     KIVAALSISKFSANQNDPRLDKISKSASLILQPENPKVSRQEMEKLKNLLDKKGLTSEI
                     NMNIFKIGDAAAPPPPPPAGQVIFSYRDGQPDQQFVLYDRHAKPGANLGQRIDKIYKDN
                     ITKVSIKINKSTPKDLLETVKQELKKKINYPVQYEILQFVD"
     CDS             8621..9655
                     /locus_tag="ctg26_11"
                     /transl_table=11
                     /translation="MIHNVKILFFICFFTACSSTEQKEIVTAGELLRQAAFYGERLQFL
                     PALETYQQAIKLAEKEKDSTVFSLAYLEMGKIYRYQSLKQKALQSEKKALSYIKSPACD
                     SLRLELYREIGDMYTLSGQADSAFHYYEMAGCRIKQAKILQQNGSNKEAETLLKTELEQ
                     TIFPKEKAEVCLALADLQITLGKLDEAEKSLSQVPPSHPHLYAALSRIAQSRGDSLQAD
                     FYHKSYLHHLSVLRQEKEQNQITQLLRTSEQKEWEKRLTDSQKAQKEQIYVWVTLLVSC
                     STGIWGYSRYRQKRNVVSLSETDFFSSESTCASTEKKNGNRFPKTGKNCCKLSTGPIRI
                     SGNG"
     CDS             9922..11118
                     /locus_tag="ctg26_12"
                     /transl_table=11
                     /translation="MKKMLFGLMTAIATFTGCESKQPAGELPRIDLTATSFAFDQVEIA
                     DEIESIEYVPLELTDESLIADVLDLCVSDEYIFVYSTRQDGVLQFDRKGKYLRCIAKTG
                     NGPGETGQIISLTVDEENRLFCVSEYFSTSFYSFDGEFIKKIENPRPYSYQFSVGPNTM
                     AELGRMYVPMNTPGMFSLGVFNWGTDDTIAFRHTIGDMDLMPLEETSLKGWIFSGSKDG
                     ILCYSEGIDTVWDVNARNIAPAFLINTGYSVEEEKEMRSSKTGNEAVDGKYSVFSFFET
                     PRHYFVKCFEGSNQSKFYLYGLDKATGELKRETSPLNAQELFKNNWTLAGIGFRNTKDN
                     GLPIWPYLSYPGKKQMVQFNTAVEIEYLKEKYPDLKKHLVLQQITEDSNPLITIYHLR"
     CDS             11161..11973
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg26_13"
                     /sec_met_domain="Peptidase_U32 (E-value: 3.5e-50, bitscore:
                     164.1, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYKNLNEKDFEIMAPVGSYESLMAAIQGGADSIYFGIEGLNMRSR
                     SSNNFTTDDLRKIVALCREHGIKSYLTVNTVIYGEDLPLMREIIDAAKEAEVSAIIAAD
                     VAAMNYANSIGQEVHLSTQLNISNAEALKFYARFADVVVLARELNLKQVHEIYRQIVDQ
                     QITGPKGELIRIEMFAHGALCMAVSGKCYLSLHEMNASANRGACMQICRRAYSVKDKDS
                     NIELDIENQYIMSPKDLKTIHFMNKMMDAGVRVFKIEDVPAVPNMSAW"
     CDS             11970..12431
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg26_14"
                     /sec_met_domain="Peptidase_U32 (E-value: 4.5e-08, bitscore:
                     26.3, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VTECYKEAVRAYCNGTFDEKKVAAWDERLRSVFNRGFWDGYYLGQ
                     RLGEWSSKYGSGATKKKVYVAKGIKYFDKIGVAEFEMESGNLKVGDEILITGPTTGAVM
                     QTIEEIRVDLKPVDETVKGERFSLKVNEKIRPSDRLYKMEKVQLEKVFE"
     CDS             12431..12838
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg26_15"
                     /sec_met_domain="HBT (E-value: 1.4e-07, bitscore: 25.6,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 2.1e-08, bitscore: 28.5,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYIFKLTDKVRDYECDLQGVVNNSNYQHYMEHTRHEFLESLGE
                     NFGKMHEKGVDGFVSRVEIQYKTSLKSGDSYISCLNAYKKGVKLVFEQDIYRASDNALA
                     TKGIVESVIVENGKLTRGEYFDEMLKRIEHT"
     CDS             12871..13950
                     /locus_tag="ctg26_16"
                     /transl_table=11
                     /translation="MINGVGDILARHLLQALGEAEAVFTEKQQLLGRIPGIGSNIAAEI
                     KRPEILQRAEKELAFIEKNNISCYYLTDTDYPVRLRECPDAPILFYFKGNTNLDATRII
                     SIVGTRNATEYGRELTESLIKDLAKVIPDLLVVSGLAYGIDICAHRNALYNRLPTVAVL
                     AHGLDRIYPSCHRNTAVEMLESGGLLTDFPSGTEPDRPNFLRRNRIVAGISDCTIVVES
                     AEKGGSLVTADIAFSYGRDVYSFPGRVGDSHSKGCNNLIRQNKAGLITSADDLLSALCW
                     DIQAGATPVQTELFFAEAETFTSEQNPVLAIMRTRNEIHINELASVLEIPVHQLSMLLF
                     ELEINGKVKALPGNLYKLS"
ORIGIN
        1 cgacacccgg atcttacgct cttatagatc cgggtgtcgg gggcggatac atgggggtgt
       61 tgggtaagtt ttattacgtg tttttcattg atttgtagct gtatttacat aaaagagcct
      121 tgtctttgat gatataggag aacaagccct ttttcctttt cttgtttacc ttgccctgca
      181 aattgtcagt ttgttttagt agaaattcaa tcacgttcga aatcggacag cacttctgcc
      241 gtagtagcgt tgatgttctt gtccaataca taaatgcggt aagacaggct cagttcttta
      301 ccgggttcca atgtgaatgc cttctgcttg gtcggtgaga aattccacat gacgtcaccg
      361 gcaggcttgt tgacagtttt gtcccatacg cgtaagggct caggatagtt taggttggaa
      421 ggggaggcaa cgattaggat acaggccttt tcgtttccgg ctttcccttg gtagtagcac
      481 caacgggctc tcgaaccgtc agcttcgtcg cgggaaaggc cttccgaggt gagcatttcg
      541 gctgtctgat cgttccagtc ttcgcgcgta cggatgcata tgccgccata acggtaagct
      601 tccatggtga tcgggctggg ctggcgaggc ggatagtggt atgatagtcg atgtaataac
      661 ctggtaagga tgttgtcccg atgttgatct ccaggcgttc gttcattgct actttttctg
      721 cgggagaatc ggggtagacc acatggtcca gtgtcgcaac aaaaccgttg tcggatacgt
      781 gttcgaagtt gcggaagcga actgttcctt gttttttgtg gagattccag aaatcgatct
      841 cgtttccttc gaacgtggtt ttcgtccagg cataccacaa accgaaatga tggtaatggt
      901 cggcgggaga acaattggtc atcacttcgc ctcccaatgt cttcaaagga tggatgaaac
      961 cgctgcgttt atagaccgag tcaacgccag gggctgggta aaccgtggta tagttgtaag
     1021 agaacaacag tttatctcct atcttatagt ctaaggtttt ccccgtgtcg acgacggaac
     1081 aggatgtttc ggaaggctga caagagccta agaacagaga aatcaaaaaa acaccaatag
     1141 aaaaaatagc agttttcata atatgacaat taaataataa tcagttatcc ggcaagacct
     1201 tgcctgtatc ggctacaaaa aaacgaaatt ttttcgtttc gcacaatccg tttgtgatat
     1261 ctgatgcaaa taaaaccagc cagcaagcag cgttctaatt gatgaaatat ttctttaatc
     1321 gtttgcgtga tatggggatt tagcatacct ttgcacgata ataaccatag attggaggaa
     1381 atttctaaat acaattaaat aacttaaatt attatcttat gtggttactt aattcttcta
     1441 tcgggaagaa gctgataatg agtatatcag gtctttttct cattctgttc ttggtgttcc
     1501 acttatgtat gaacattgcg gcagtatttt ctggtgaagc gtataacgtg atttgcggtt
     1561 tgctgggttc taactggtat gctttgctcg gtacattggt gttggctgca ggtgtagtcg
     1621 tgcacttcgt gtatgctatt atcttgactc tgcagaatcg taaggctcgc ggtaacgacc
     1681 gttatgccat caacgctcgt ccgaaaggtg ttgaatgggc ttctcagaac atgtttgttt
     1741 tgggtgtgat cgttatcctg ttcatggttc tgcactttac tcagttctgg tacaacatga
     1801 tgtttgccga actggcaggt attcatggtg acattcatcc gcaggatggt gcagcgttta
     1861 tcaatttcta cttccagggc aatgttgtga atacggtgtt gtatctgatc tggttcgttg
     1921 ctctgtggtt tcacctgact cacggtttct ggtctgcgat tcacacaatt ggctggaaca
     1981 ataccgtttg gttaagccgt tgggaatgta tctctaaatg ggttgccact attatttgtg
     2041 gcttattcgc tgttatcaca gttatcttct acctgaacgg tgtaggtgct taatttcgga
     2101 tattattttt tcaatttgaa aataaaacat tatgactcaa atagattcta aaattcctca
     2161 aggcccgttg gctgagaagt ggacaaatta taaaaatcac cagaaattgg tgaatcccgc
     2221 aaacaaacgt cgtttggaca taattgtagt aggtactggt ctggcgggtg cttctgctgc
     2281 tgcctctctg gctgaaatgg gattcaatgt attgaatttc tgtattcagg actctccccg
     2341 tcgtgcacac tctatcgctg cacagggcgg tatcaatgcg gcaaagaatt atcagaatga
     2401 tggtgactcg gtttatcgtc tgttctacga tacaatcaaa ggtggtgact accgtgcccg
     2461 cgaagcaaac gtctatcgtt tggctgaagt gtcaaactct attatcgacc agtgcgtagc
     2521 acagggtgta ccattcgctc gcgaatatgg tggtctgttg gataaccgct cattcggggg
     2581 tgctcaggta tcccgtacgt tctatgctcg tggtcagacc ggacagcagc tgctgttggg
     2641 tgcttactct gcattgagtc gtcagattgg tttgggaaag gtgaagatgt acacacgcca
     2701 tgaaatgctg gatgttgtga aggttgacgg acgtgctcgc ggtattattg cccgtaattt
     2761 gattaccggt aagatcgaac gttttgccgc tcacgcagtc gttgttgcga caggtggtta
     2821 tgtaaataca ttcttcttgt ctactaacgc gatggcgtct aacggttctg ctgcatggca
     2881 gtgctacaag aaaggggctt actttgctaa tccttgtatg gtgcagatcc acccgacttg
     2941 tgtgccggtg aaaggtgact tccagtctaa gctgactttg atgtcagaat cactgcgtaa
     3001 cgacggccgt atctgggttc cgaagaagct ggaagatgcg aaggcattgc aggccggaac
     3061 aaaaaaggga aaggatattc ctgaagcaga tcgcgactac tatctggaac gtcgttatcc
     3121 ggcattcggt aacttggttc ctcgtgacgt ggcttcacgt gccgctaaag aacgttgtga
     3181 tgccggtttc ggtgtaaata gcacgggctt ggctgtattc ctggatttct ccgatgctat
     3241 caaccgtctg ggtaaggaag tggttaaaca gaaatatggt aacctgttcg atatgtacga
     3301 agagatcacg aacgatgatc cgtacgaaac tccgatgatg atttatcctg cattgcacta
     3361 ctcaatgggt ggtttgtggg tagactatga attgatgact tctattccgg ggctgttcgc
     3421 aattggtgaa gccaacttct ctgaccacgg cgctaaccgt ctgggtgctt ctgctttgat
     3481 gcagggattg gccgatggtt acttcgtatt gccttacacg atccagaact atctgtctga
     3541 ccagatccag gttccgcgct ttagcactga cctgcctgaa tttgtggaag cagaaaaggc
     3601 tattaacgcc cgtatcgcga agttgatgaa cgtgaagggt aaagaaacag tcgattctat
     3661 ccaccgtaag ctgggacata tcatgtggga acacgtcggt atggcacgcg acgcggaagg
     3721 cttgaaagaa gctatccaaa tgttgaaaga cctgaagaag gaattctgga gcaatgtatt
     3781 cattccgggt gaggccaata gcttgaacgt ggaattggac aaggcattgc gtttggctga
     3841 ctttatcgaa atcggtgcgt tgatggcaca cgatgcgtta gaccgtgcag aatcttgtgg
     3901 tggtcacttc cgtacggaac atcagaccga agaaggcgaa gctatgcgtc atgacgataa
     3961 gttcatgtac gtctcttgtt gggaatacca gggtgaagac aaagacccgg ttatgctgaa
     4021 ggaagatttg aactatcagt tcgttgttcc tcaaacacgt aactacaaga agtaataatc
     4081 atcaatcaca aaaattagaa tcatggataa agatataaag gtaacactta aagtttggcg
     4141 tcagaaaggt ccgaaagata aaggacagtt tgagacttac caaatcgaca aaatcaatca
     4201 gagtgtttct ttcttggaaa tgttagacat tttgaatgaa cgtttggtta gcgaaggcaa
     4261 agaacctatc gtattcgacc acgactgccg tgaaggtatc tgcggtatgt gttcattgta
     4321 tgtaaacgga catccgcacg gaccggcaac aggtgcaaca acctgtcagc tctatatgcg
     4381 ccgtttcaat gatggtgaga cgattacgat cgagccgtgg cgttctgctg gtttcccggt
     4441 aatccgcgac ttgatggtag accgttatgc ttatgataag attatccagg caggtggttt
     4501 cgtttctgta aacacaggtg gggttcctga tgctaatgca attcctattt ctaaggctga
     4561 tgcggatttg gctatggatg ctgctgcttg tatcggctgc ggtgcttgtg ctgctgcttg
     4621 taagaacggt tcagctatgc tgttcgtctc tgcaaaggtt agccagctgg ctcttttgcc
     4681 tcagggtaag gtggaagctg ctcgtcgtgc aaaagcaatg gttgctaaga tggatgaact
     4741 gggctttggt aactgtacga acactcgcgc ttgcgaaatg gaatgtccga agaacatctc
     4801 cgttagcaac atcgctcgct tgaaccgcga gttcatctct gctaagttac aagactaata
     4861 cattatatat gtatgtatat ggaaaagccc gtcgccaatg gcaacgggct ttctttatgt
     4921 tcgttcaaac ccacaaaaag cgcactccct ataataaaag tggatgcggc ttttttgttg
     4981 ctttccagtg aaacagtctc tcgattccct ctctgcaaag actttgttaa ccttagatct
     5041 aaaatactat gaaaaaaact cactgcaaat ataaagtata tttactgaat acgcaagagt
     5101 ttgtaattac attttattgc aaatttgcta ctttttgttt taaaattgac actgtgtgcg
     5161 gattcacact gttattatat caacaatcga tcgattctga cacttgagag tcgctttgaa
     5221 atccgtatcc tgtatgaaat ttgtcgggga tggaatccag aatgtcgaat aatgcttcca
     5281 ctgtttccgc acgtagcatg gcgacgcgtg tctgcttgaa gtctgcaata cctttaaaca
     5341 gcggagttgc agccaaatgg cggcgaatgt ggagaattcc ccggcgctca tccaaacgtt
     5401 ccacgctttg ttccacctgc tttttcagta tgtccagata ccatgaaaaa gattcggcag
     5461 gcaatgtctc gcctgtatcc agataatgcc tcacttctct gaaaatccag gggcggccta
     5521 tgctgccccg gccaatcata acggcatcca cgccatattg ttcgaaacgt tgtttgcaga
     5581 tttcggcgga agtcacatcg ccattgccga tgatgggaat ttgtatacgg ggattgtttt
     5641 ttacttcacc gatcagtgtc cagtctgcct ctcctgtgta catctgtgcc cgggtacgtc
     5701 cgtggatgga aagggctgcg ataccgcaat cctgtagctg ttcggccaag tctacgatga
     5761 tccggttgtc ggcatcccag cccaagcggg tttttacggt gacagggatg ttcaccgctt
     5821 tgacgacttc acgggtgatg tccagcatca gtggaatatt gcgcagcatg ccggcgcctg
     5881 ctcctttgcc tgccactcgt ttgacagggc aaccgaaatt gatatcgaga atgtccggat
     5941 gagcggcttc gcaaatttgc gcggcttcga ccattgtcgg aacatcacgg ccatatattt
     6001 gtatggcgac cggacgttct tcatccgcca cattcagctt ttgctgtgtt ttatttacac
     6061 tgcggattag ggcgtctgct gaaacgaatt cggtataaac catatcggca ccaaaacgtt
     6121 tgcacatcaa ccggaaagaa atatctgtaa cgtcttccat cggagctaag aagacggggc
     6181 gttcgcctaa atctattgta cctattttca tatttatatt atcaatgacg gggacaaagg
     6241 tactgatttc ctgctaaaaa cagggataaa aggatatcta ctaaaaaata tagtaaaata
     6301 actatatgat atagttgtgt tactaaataa tatagttgta tttgtgcatt cctctaacaa
     6361 aaaacggatt atggttagat taacatcaaa agaagaagaa atattgggct acttttgggc
     6421 gaaaggcccc ctgttcgttc gcgaactact cgacttacag gaagaatcta agccgcatta
     6481 taacaccttg tccacgattg tccgctcatt ggaagaaaaa ggatatatcg gatacaaggt
     6541 atacggtaat acgcaccaat actatgcact ggtatcggaa gacgaatacc ggcgtaattc
     6601 cttgaaacag gtgatcagca aatattatga caactcgtac acccgtgtcg tttcgacgct
     6661 gatagaagaa gaggtgctca cgatcgacga gttacagaag ctgatccagc agataaaaaa
     6721 caaataaaaa accaacgctt atggacgctt ttcttctata catattaaaa tctggtattt
     6781 gcctgacagt cttttatgtc tgtttcaagg cattattcag taacgacacg tttttccggt
     6841 tcaaccgctg gatattactg gtagggacag gagtttgcat gttgctgcca ctttgccgga
     6901 tccaaacagc ccggcctttt cctcttagcc ggccagtcag ccaactggag atagttttct
     6961 atgaagaaga gatgaaagcg tttcctgttc cggaaagcaa agaagaaatt acgattccga
     7021 cagagcagag aaatatatct gttccctgga cgggaattat cgggattgct tttctaacag
     7081 gcagtggtat ctgcctgacc acaacgattc tgtcattcgg aaaaatgtat caactaacaa
     7141 gaaaaaacag gaaactaaaa caggggaaat acacgttaat cctgactccc gatcccgtat
     7201 cccctttcag ttggggacgt tatatattcc tttcggaaaa cgattaccgg aaccatccga
     7261 acgaaatcct catgcacgaa aaaatgcacc tccgctataa ccattcggtc gatctgatct
     7321 atatgaaacg attcttcttc tgcaatggtt taatcctgcc gtatggttat taaaaaggga
     7381 attacggggc atacacgaat accaggcgga taaaggcgta ctcagtcaag gcatcgatgc
     7441 aacaaaatat caactattac tcgtgaaaaa agctgtcggc tccagcctct acactcttgc
     7501 caacagcttc aatcacagta aaattaaaaa acgtattact atgatgttaa aaaagaaatc
     7561 aaacaattgg gcccggttga agcttgcgct cctggtcccg gtaggcttcg cggccttaag
     7621 tgcattcgcc cgtccggaaa caagtccgcc gccggcagcg acaatgaccg acaacattca
     7681 tctatcgatt aacaaaagta cggtaaatca ggaaacgatg caacaggatc atgcagtttt
     7741 cctcacctac aaagaatcgg gttcggagga tctgaacagt attgtatgca aaactctgga
     7801 cagaatcaga acacgagtag cggagggaca attcaagaac gccctggaag ttactgttaa
     7861 tccggccttc gacgatatcc cggcttctta tctggaaaca gtaaaagatg ttttggaaga
     7921 aagagatatt aaatgcaaga tcgacatgac tgttccgaat actatcatgg atgatgttgc
     7981 caaaccttac cgcaaatatg acgatgtggt ttatctgatt cagaataaaa agattgtcgc
     8041 agcactaagc atcagtaagt ttagtgcaaa ccagaatgat ccgaggctgg ataagatatc
     8101 caaatcagct tccttaattc tccaacctga aaatccgaaa gtatccagac aagaaatgga
     8161 gaaattaaaa aacttgttgg acaaaaaagg attgacaagc gaaatcaaca tgaatatttt
     8221 caagatcgga gatgctgcgg ctccacctcc cccacctcct gccggacagg ttattttcag
     8281 ttaccgggac gggcagccgg accaacagtt cgttttatac gatcgccatg ccaaaccggg
     8341 agccaatctc ggacaacgca tagacaagat ttacaaggac aatattacga aagtaagtat
     8401 aaagattaac aaaagtactc ccaaagacct gttggaaacg gttaagcaag aactgaaaaa
     8461 gaaaatcaat taccctgtcc aatacgagat cctgcaattc gtcgattaaa atcagaaaca
     8521 cggattatct atttatcatc ctctccgttt acaaaacctg ctccaggggg taaacggaga
     8581 ggaatattat tatctttact ccttcaaaag aaggattcag atgatacaca atgtaaagat
     8641 actctttttc atttgctttt tcaccgcctg ttcttctacc gaacaaaaag agattgtcac
     8701 cgccggagag ctccttcgac aggctgcttt ctatggggaa agattgcaat ttcttccggc
     8761 attggaaacc tatcaacagg caatcaaatt ggcggagaag gagaaagaca gcaccgtctt
     8821 ttcccttgcc tacctggaaa tgggaaaaat ctatcggtat caatctttaa aacaaaaggc
     8881 actacaaagt gagaaaaaag cattaagcta tatcaaaagt cctgcctgcg attcgctacg
     8941 gctggaactt taccgggaaa taggggatat gtataccttg tccggacaag cagacagtgc
     9001 ctttcactat tatgaaatgg ctggatgtcg gataaaacag gcaaagatat tgcaacagaa
     9061 tggaagcaat aaagaggctg aaactttatt aaaaacggag ttggaacaaa cgattttccc
     9121 gaaagagaaa gcagaagtat gtctggcttt ggctgatttg cagattactt tgggaaaatt
     9181 ggacgaagcc gaaaagagtt taagtcaggt ccccccttcc cacccgcatc tgtatgctgc
     9241 cctgtcccgc atcgcccaaa gccgtggaga cagcctgcaa gctgatttct accacaaaag
     9301 ctacctccat cacttatccg tcctgcgaca ggaaaaagaa caaaatcaaa ttacccaact
     9361 ccttcgtacc tcggaacaga aagaatggga aaaacgttta accgatagcc aaaaggcaca
     9421 aaaagaacaa atatatgtct gggtcacgct acttgtctct tgcagtaccg gaatctgggg
     9481 atattcccgc taccggcaga aaagaaatgt cgtttccctg tccgaaacag atttcttttc
     9541 ttcagaatct acctgcgctt ccaccgaaaa gaagaatgga aaccggttcc caaagactgg
     9601 gaagaattgt tgcaagcttt caaccggacc tatccggatt tccgggaacg gctgaaaagg
     9661 aaaataccaa agttgagcga acaggaatgg cgcatgtgct gcctgatcaa aatggaagtt
     9721 cccccttcta ctgccgccat gctcctttgc tgcacgaacc aggcgatttc gatgcgccgc
     9781 gtacgcctgt accagaaaat cacaggtgaa aagggcactc ctgagctgtg tgattccttt
     9841 attcgtgatt tttaagcaga tgtgaactga tgtgaaaccg gggaaatagc cgtatcttct
     9901 acttttgtct aaaaaaagcg tatgaaaaag atgttgttcg ggcttatgac agccattgcc
     9961 acttttaccg gatgcgaatc caaacaaccc gccggagaac tcccccggat cgatctgaca
    10021 gcaacaagtt ttgctttcga tcaagtagag attgcagacg aaatcgaatc catcgaatat
    10081 gttccgttgg aactaacgga tgaatccctg atcgcagacg tattggatct gtgtgtttca
    10141 gacgaatata tcttcgtcta ttctacccgt caggacggtg tcttgcagtt cgaccggaaa
    10201 gggaagtact tgcgctgcat cgctaaaaca ggaaacgggc cgggagaaac cggacagatc
    10261 atttcgctaa ccgtagacga agagaaccgc ctcttctgtg tcagcgaata cttctccacc
    10321 tctttctact cctttgatgg agaatttatc aaaaagatag agaatccgcg cccttactcg
    10381 taccaattct ctgttggccc gaatacgatg gcggaattag ggaggatgta tgttcccatg
    10441 aacacgccgg gcatgttcag tctcggagtc tttaattggg gcacagacga tacgatcgca
    10501 ttccggcata cgatcgggga tatggatctg atgccgttgg aagaaacgag cctgaaaggt
    10561 tggatattca gcggcagtaa ggacggcata ctatgctatt cggaagggat agacacggtc
    10621 tgggatgtaa atgcaagaaa tatcgctccg gcttttctta tcaacacggg atattctgtc
    10681 gaggaagaaa aagaaatgcg ctcttccaaa accggtaatg aggcggtaga cgggaaatat
    10741 agcgtcttca gcttctttga gacaccccgg cattacttcg ttaaatgttt cgaaggttcc
    10801 aaccaatcca aattctattt gtacggcttg gataaggcta ccggtgagtt gaaacgtgaa
    10861 acttctccgc ttaatgccca ggaattattc aaaaacaact ggacgctggc aggaataggc
    10921 ttccgaaata cgaaagacaa cggtcttcct atctggcctt acctgtctta tcccggcaaa
    10981 aaacaaatgg tacagtttaa tacagccgtg gaaatcgaat atctcaaaga gaaatatcct
    11041 gatctcaaga agcatctggt cctgcaacag ataacggaag attcaaatcc gctcatcacg
    11101 atttatcatt tgcgctgatc ttctcggata ttattcctac ctttgcgaac gaaccagtaa
    11161 atgtataaga acttgaacga gaaagatttt gaaataatgg cgcctgtcgg ttcgtacgaa
    11221 tcactgatgg cggctatcca agggggagcc gattctatct atttcggtat cgaaggattg
    11281 aatatgcgtt cgcgctcttc caataacttt acgacagacg atttgcgcaa gatcgttgcg
    11341 ctttgtcgtg agcacggtat taagagctat ttgaccgtca atacggttat ttatggggaa
    11401 gacctgcctc tgatgcgcga gattatcgat gcggcgaagg aggcggaagt ttcagcgatc
    11461 attgcggccg atgtggcagc tatgaactat gccaacagca tcggacagga ggtgcatctt
    11521 tccacacagc tcaacatttc caatgcggaa gcactgaaat tctatgcccg ttttgctgat
    11581 gttgtcgtct tggcgcgtga gctgaatttg aaacaggtgc atgaaatcta tcggcagatc
    11641 gtcgaccagc agattacggg accgaaagga gaactgatcc gtatcgaaat gtttgcccac
    11701 ggagctctct gtatggccgt ttccggtaaa tgttacctga gcctgcacga aatgaacgct
    11761 tccgccaacc ggggagcttg catgcagatt tgtcggcgtg cttattcggt aaaagataaa
    11821 gacagcaata tcgaactgga tatcgaaaac cagtatatta tgtcgcctaa agaccttaag
    11881 acaattcatt tcatgaataa gatgatggat gcaggtgtac gggtattcaa gatcgaggac
    11941 gtgcccgcgg tcccgaatat gtccgcctgg tgaccgaatg ctataaggaa gctgtgcgtg
    12001 cctattgcaa tggcacgttc gatgaaaaga aagttgccgc ttgggacgaa cgcctgcgca
    12061 gtgtgttcaa ccgaggattc tgggatggct attatttggg gcaacggttg ggtgagtgga
    12121 gtagcaaata tggctccggc gcgactaaga agaaagtgta tgttgccaaa ggaatcaaat
    12181 atttcgacaa gatcggcgtg gcggagttcg aaatggaatc cggtaacctg aaagtgggtg
    12241 atgagatcct gattaccgga ccgacaacgg gtgcggttat gcagacgata gaagaaatcc
    12301 gtgtggactt gaagccggtg gacgagaccg ttaaaggtga acggttctct ctcaaggtga
    12361 acgagaagat tcggccgtct gaccgattgt ataaaatgga aaaggttcaa cttgaaaagg
    12421 tatttgaata atgaaagagt atatttttaa actgacagac aaggtccgtg actacgaatg
    12481 cgacctgcaa ggagtggtca acaactccaa ttatcagcat tatatggaac atactcggca
    12541 tgaattcttg gagtcgcttg gcgagaactt cggaaagatg cacgaaaaag gggttgacgg
    12601 atttgtatcg cgggtagaaa tccagtataa gacctcgctc aagagcggcg acagctatat
    12661 ctcttgcctc aatgcctata aaaaaggagt caagctcgta ttcgagcagg atatatatag
    12721 ggcttctgac aatgcattgg cgacgaaagg aatcgtcgag tcggttatcg ttgagaacgg
    12781 aaagttgaca cgcggtgaat atttcgacga aatgctaaaa agaatagaac atacatgact
    12841 gacaaacgga tttaccaaat cggccttact atgataaacg gcgtgggaga tatcctggcg
    12901 cgtcatctcc tgcaggcttt gggagaagca gaggctgtgt ttactgaaaa gcaacagttg
    12961 ttaggaagga tccctggtat cggcagcaat attgctgccg aaatcaaacg cccggaaatc
    13021 ttgcaacggg cggaaaaaga gttggctttt atcgagaaaa acaatatttc ctgttattat
    13081 ctgactgata cagattatcc ggtgcgcttg agagaatgtc cggatgcccc tatacttttc
    13141 tattttaagg gaaatactaa ccttgatgcg acccgtatca tcagtattgt gggtactcgc
    13201 aacgcgaccg aatatggtcg ggagcttacc gaatccctta taaaagactt ggcaaaagtg
    13261 atcccggact tgttggtcgt gagtggattg gcttacggca tcgatatctg tgctcaccgg
    13321 aacgctttgt acaaccgact tccgactgtt gctgtgctgg cgcatggctt ggatcgtatc
    13381 tatccttcct gccatcggaa tacggctgtc gaaatgctgg aatcgggcgg tctgttgacc
    13441 gattttccca gcggtacaga accagaccgt ccaaatttcc tccggaggaa ccggattgtc
    13501 gccggaatct cggattgtac gatcgtggtt gaatcggcag aaaaaggagg ctctttggta
    13561 actgccgata ttgcattctc ttatggccgg gatgtctata gctttccagg gcgtgtcggt
    13621 gacagccatt ccaaaggatg caacaatttg atccgacaaa ataaagccgg cctgatcact
    13681 tctgcggacg atctgctctc cgctctttgt tgggatatcc aagctggggc tactcccgtt
    13741 caaacggagt tgtttttcgc cgaagcggaa acattcacct cggaacaaaa tccggtttta
    13801 gccattatgc gaacgcggaa tgagattcat atcaacgagc ttgcctcagt gttggagata
    13861 ccggtacatc aactctctat gctattgttc gaactggaaa taaacgggaa ggtaaaagcg
    13921 ttgccgggaa atctctataa gctgtcctga ccggcttttt cgtatacgat ttgtatgtgg
    13981 gagaagaaac ggaacctcta taaacaatta aaggctgtct cacgacaacc cctaaccaac
    14041 tttgttaacc ttaaatctaa tactattatg aaaaaaccac attgcaaaga tactctcgtc
    14101 aagagcgttt gtcaagcatt ttgttgctaa tacttgttaa tcagatgagc ataaatagca
    14161 aaaagatttt aatcggctat aaagagtcct ttaaactgcg ttattttgtt aaatcgagtc
    14221 cttgaaacag gtacggatag tccgtttcga tcacgtcggg acgagtgctg atctctgacc
    14281 ggtaaccggc ggttttctct gtttccgttt tcgcgcgatc atgtgtcgga gcaacggaaa
    14341 tcatgcacat gactccgtta cggtgcagag cgtcatacag tggttgctgt tcaggcttca
    14401 tcttcgggcc tacataagcc attacctgtt tccaggggat gccggctttt tcataattat
    14461 cgaattcttc ccgattctta caccagcaag aaaacatcgc atccggtttc cggtcgagat
    14521 aatagcgggc ttgactggcg ttatgtaccg tgtacatgac gttaacaggc ttttctgttt
    14581 ctataaaatc agccataact tctaaaggta catccttgat atccaaattc aggattgttt
    14641 tgcctttgct ccattccagg cattctttta aagttggaat tttgaaggct gtcacgttgc
    14701 cgtttcggtc caccagattg aattgttgca gttctgcata agtgtaatct gaaacctttc
    14761 ctttcccggt agttgtccgg tcgatggttt cgtcgtgcat caatacgatt atcccgtctt
    14821 ttgtcaaacg cggatctatc tcgaaaaacg attccata
//
