LOCUS       c00023_gnlPro..        24709 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AJNCFDOD_23.
ACCESSION   c00023_gnlPro..
VERSION     c00023_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 00:02:27
            Original ID  :: gnl|Prokka|AJNCFDOD_23
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 228138
            Orig. end    :: 252847
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24709
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[238138:242847]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14709
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24709
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24709
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="2"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             1875..2207
                     /locus_tag="ctg23_235"
                     /transl_table=11
                     /translation="MEWIFNQLRERPELAIFLTIFLGFWLGKLRIGKFTLGTVTSVLLV
                     GVLVGQLNIAVPGPIKSVFFLLFLFAVGYKVGPQFFRGLKKDGLPQVGFAVLMCVSVLL
                     VTWLLA"
     CDS             2207..3568
                     /locus_tag="ctg23_236"
                     /transl_table=11
                     /translation="MMGYNAGEAAGLLAGSQTISAVIGVAEDTMANMGLDEAQRQSYVN
                     IIPVSYAVTYIFGTAGSAWVLSSIGPKMLGGLEKVKAACKELEAKMGSSLADEPGFMPA
                     ARPVTFRAYRVENEWFKNGKRVIDLEVYFRQHDKRLFVERLRKSGVVVEVSMNIQIEPG
                     DEVVLSGRREYIIGEESWIGPEVQDAQLLDFPAEKLPVTITRKTVAGKTVAVIRREKFM
                     HGVSIRSIKRAGISIPVLAQTVVDAGDVIEVVGTRQEVEAAAKRLGYIDRPTNQTDMIF
                     VGLGILVGGLFGALSVHIGGIPISLSTSGGALIAGLFFGWLRSKHPTFGRIPEPSQWVL
                     NNVGLNMFIAVVGISAGPSFVQGFHDVGISLFLVGAAATTLPLIIGLLLARYVFKFHPA
                     LALGVCAGARTTTAALGAVQDAVESETPALGYTVTYAVGNTLLIIWGVVIVLLI"
     CDS             3845..3958
                     /locus_tag="ctg23_237"
                     /transl_table=11
                     /translation="MDTKLLEKKMESISPFELKNRLIDMADESLKKPPVPC"
     CDS             4041..5477
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GlcNAc_2-epim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_238"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.8e-21, bitscore:
                     71.5, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="GlcNAc_2-epim (E-value: 0.0058, bitscore:
                     10.7, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VPPHHGFARGHCRHPRKKGIASRFEAFLKKNNNVPGAKLLEQTYN
                     YLLMQHAADPDSLVHEWAESIVGDQYPVPDRILHFTEILVQDYLSQEMCDNRPPRGAYD
                     LFATEGGTAAMCYIFDSLQENFLLNKGDGIVLMVPAFTPYIEIPQLSRYQFRVTKIHAN
                     RMNNEGMHLWQYSDEDIDRLKSPKIKALFVTNPSNPPSYTLSPDTMARIVSIVRNDNPN
                     LMIITDDVYGTFSPHFRSFMAEIPYNTLCVYSFSKYFGATGWRNAVIALHEFNLFDKLI
                     AKLPKEKREILHHRYSTLTLEPEKLKFIDRMVADSRQVALNHTAGLSLPQQMQMGLFAA
                     FALLDKENKYKQKMQEIIRRRLHALWENTGFTLTEDPLRVGYYTEIDMLVWAKKFYGDD
                     FVEYLKRTYSPLNVVFRLAKETSLVLLNGGGFDGPEWSVRASLANLDEKDYATIGQGIK
                     KILEEYAKEFFKNGKAKGKN"
     CDS             complement(5511..6824)
                     /locus_tag="ctg23_239"
                     /transl_table=11
                     /translation="VRIKFFFFILVLFLLGLGGMLVYLLSGKPSLYLYVLEGLIGFILI
                     YLIVFYNKIVKPMNTIGSGMELLREQDFSSRLSRVGQYEADRIVNIFNRMMEQLKNERL
                     RMREQNHFLDLLIQASPMGVIILTMDDEVSQLNPMAVKMLGVRMEEAMTKRLDQMDSPL
                     AAELSSIPKDETAVVRLNDANIYKCTHSSFIDRGFKHPFFLIERMTEEVMRAEKRAYEK
                     VIRMIAHEVNNTTAGITSTLDTVEQALSTEDDMEDICDVMRVCTERCFSMSRFITRFAD
                     VVKIPEPTLAPVQLNELVSMCKRFMEGMCNDRNIELRLECDPEVGMVRMDASLFEQVLV
                     NIIKNAAESIEGDAGENGQQGEIIVRTTAPASVEVVDNGPGISKETEAKLFSPFFSTKP
                     NGQGIGLVFIREVLSRHGCTFSLRTYSDGLTRFRILFN"
     CDS             complement(6815..8176)
                     /locus_tag="ctg23_240"
                     /transl_table=11
                     /translation="MILIIDDDSAVRSSLSFMLKRAGYEVKTAPSPREAMDIVRAEAPA
                     LILMDMNFTLSTTGEEGLTLLKQVKVFRPDVPVILMTAWGSIQLAVQGMQAGAFDFITK
                     PWNNAALLQRIETALELTAAPKEVPEEQTTALNRSHIIGKSKGLMEVLNTVARIARTNA
                     SVLITGESGTGKELIAEAIHINSQRVKQPFVKVNLGGISQSLFESEMFGHKKGAFTDAS
                     ADRIGRFEMANKGTIFLDEIGDLDPSCQVKLLRVLQDQTFEVLGDSRPRKVDVRVVSAT
                     NADLRKMVSERTFREDLFYRINLITVKLPSLRERREDIPLLARHFADRQAEVNGLPRTD
                     FSADALNFLSRLPYPGNIRELKNLVERTILVSGKPVLDATDFDAQYLRHDEPAKAAEGT
                     SFAGMTLDEIERQTILQALEQHKGNLSQVAVSLGISRAALYRRLEKYNIQVPCA"
     CDS             complement(8320..9807)
                     /locus_tag="ctg23_241"
                     /transl_table=11
                     /translation="MKKNILLAVCFLMPLATMAQNDTLGHERNITLSEAIVLARTQSVD
                     AAVALNELKTAYWEYRTFRADLLPEVNFTGTLPNYNKSYSTYQNSDGSYSFVRNNTLGL
                     SGQLSVDQNIWFTGGKLSLTSSLDYLKQLGSGGAKQFMSVPVSLELTQPVFGVNTLKWN
                     RRIEPVRYAEAKAEFISATEEVTMKTITYFFELLLAKESLATAMQNKTNADRLYEVAIA
                     KRKMGQISENDLLQLKLNSLQGKADVTEAESNLNAKMFQLRSFLGVSEQESLNPVLPAT
                     VPDIKMEYDRVLNKALERNSFAQNIRRRQLEADYEVATARGNLRSIDLFASVGYTGQNH
                     EFSSAYRDLLDNQIVQVGVKIPILDWGKRRGKVRVAKSNREVVLSRIRQEQMDFNQDIF
                     LLVANFNNQAQQLDIAEEADVIAEKRYKTSVETFMIGKISTLDLNDAQNSKDEARQKHI
                     SELYYYWYYFYQLRSLTLWDFERDTELEADFEEVVRG"
     CDS             10001..10513
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_242"
                     /sec_met_domain="Glyoxalase_4 (E-value: 1.9e-24, bitscore:
                     80.9, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNFFIKEEFSFFVLLYTFIKKDTILTLIYIVMKISHIEHLGIAV
                     KSIEEALPYYENVLGLKCYNIETVEDQKVRTAFLKVGDVKIELLEPTSPESTIAKFIEK
                     NNGNGGMHHLAFTVEDGVAGALAEVEEKGIRLIDKAPRKGAEGLNIAFLHPKSTLGVLT
                     ELCEKPE"
     CDS             10572..12125
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_243"
                     /sec_met_domain="CT_Btheta (E-value: 4.7e-290, bitscore:
                     956.9, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIDRRAAARLGGGEKAIAKQHEKGKYTARERIAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYIFAQDFTVSAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAQTEEEGLALIRKLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDNPN
                     KPYDMYEVIGAIIDNGEFLEIQKDYSKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKEQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRIIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             12157..13089
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_244"
                     /sec_met_domain="OAD_gamma (E-value: 3.8e-16, bitscore:
                     54.3, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLMLVLGFCSSCKEQKSNNKLLLNEVLVNNESNYQ
                     DDYGVHSAWIEIFNRSYGSADLAGCYLKFSSQPGDTASYFIPKGDVLTLIKPRQHALFW
                     ADGEPRRGTFHTNFKLDATNANWIGLYDSGKKLLDQVIVPAGTLKANQSYARVSDAADQ
                     WEVKGGSEDKYVTPSTNNKTIDSNAKMEKFEEHDSVGIGMAISAMSVVFCGLILLYISF
                     KIIGKISVNLSKRNAMKAKGITDKQEAKEKQLGQAPGEVFAAISMAMHEFQSDVHDVED
                     TILTITRVKRSYSPWSSKIYTLRETPHKK"
     CDS             13113..13547
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 67.3; E-value:
                     2.7e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_245"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2e-20, bitscore:
                     67.3, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNVYKVAIGDIEDNIAHVEVNGTPYKVEMEKAPKVV
                     VKPVARPAATSAPAAPATPVVKPAAASTGKSGVKSPLPGVILDIKVNVGDTVKKGQVII
                     ILEAMKMENNINADKDGKITAINVNKGDSVLEGTDLVIIE"
     CDS             13549..14709
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_246"
                     /sec_met_domain="OAD_beta (E-value: 1.8e-151, bitscore:
                     498.9, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEFITFLGNNLADFWTYTGFANATVGHVVMLLVGLFFIYLAVAK
                     EFEPMLLIPIGFGMLIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLVGAAAQFGIFGAYMIALAIGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRWLTSKNERLIRMKPPRVVSHTEKVMFP
                     IIGLLLTTFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDTITILLGLTVGAS
                     TQASEFLTLDSIKIFGLGALSFVIATASGVIFVKIFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             14879..15082
                     /locus_tag="ctg23_247"
                     /transl_table=11
                     /translation="MRKLFISLCFSACCSLLAAQTTNPIQEAMANYDYETALMLIDQET
                     PTVPLLYQKGKALKGWAITLKL"
     CDS             15256..16230
                     /locus_tag="ctg23_248"
                     /transl_table=11
                     /translation="MNMKRYRESLKESNLLAERDSSAYVLHLRAESMGQVYDNTEIMHV
                     IDAYLDIQKRYPNDYLSAAKLGNIYVAGHQYEDAISITEKYRSIDSTNVLVNRINAQAY
                     CLNKDYPKAIERYEQLLQEKDSSFQTCFYAGISYYALEDFYPAHDLLERALKDDNTNIN
                     VLYYLGRACSKTSWKEDGVTYLETAVSLAMPSDSVMSRLYVGLADCYKMAFQYTDQANT
                     LLTQYEKYDRQKHKLLYDAAFIYYYYLKDASKAERYLTAYLKTRPKNSKDKVQEVDADG
                     VPIIGEDNRYNAAENWLKDIREKRKKEDFFKGKVDTASVTPIK"
     CDS             16339..16917
                     /locus_tag="ctg23_249"
                     /transl_table=11
                     /translation="MKKVFLILGTLLLSLSTYAAMNVNKIDPPFWYTGMQNPELQLMVY
                     GEGIGNAAVSVNYPGVSLSSTVKLESNNYLLVYLKLDKDVKPGKFNLTFTEGKKKLVKE
                     YELKARNKKGCEHKGFDASDALYLLMPDRFANGNPDNDQIAGMAEYKIDRNDPNARHGG
                     DLAGIEQHLDYFSDLGVTASGLLRYWKTT"
     CDS             16914..18188
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_250"
                     /sec_met_domain="Alpha-amylase (E-value: 7.6e-50, bitscore:
                     165.1, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGGSYHGYATTDYYKVDPRFGTNEEYKQLIEKAHARGIKIVMDM
                     IFNHCGVEHVWIKDMPSKDWFNNPDHENNFVQTSFKLTPHVDPYTSQYDADQMNDGWFV
                     PSMPDLNQKNPHVYRYLVQNSFWWIEFANIDGIRMDTYPYADYDAMSNWMKELNEEYPN
                     YNTVGETWVTEPAYTAWWQKDSKLSAPKNSNLKTVMDFSFFDKINTAKNEQTETWFKGL
                     DRIYNNFVYDFLYPNPASVLAFIENHDTDRFLGEGNNLPMLKQASTLLLTTRRIPQLYY
                     GTEVMMNGVKSKSDGYVRKDFPGGWTGDATNALTPAGRTKIQNECYDFYKTILNWRKGN
                     DVIAKGSMVQFMVQNGVYAYARQYEGKTVFVMLNGTDAETTVPLKFYKEILKNSKQGKD
                     ILSGKAITFGEELKMGPRESLVIEL"
     CDS             complement(18659..19669)
                     /locus_tag="ctg23_251"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTREMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCKHPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYEENVALTKKVVDYAHQFDVTVEGELGVLAGVEDEVSAEHHT
                     YTNPEEVIDFATRTGCDSLAISIGTSHGAYKFKPEQCHVDPATGRLVPPPLEFAVLDAV
                     MEKLPGFPIVLHGSSSVPQEEVDTINKYGGKLEAAIGIPEEQLRKAAKSAVCKINIDSD
                     SRLAMTAAIRKTFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSENKLAQLD"
     CDS             complement(19952..20959)
                     /locus_tag="ctg23_252"
                     /transl_table=11
                     /translation="MRKLLVLCSFWLCVATLGAQNAERKLYSVAFYNLENLFDTIHDAG
                     KNDYEFLPDGSYQWTAKKYESKLQNLSKVLGSLSRDLVPEGPAFIGVAEAENSRVLEDL
                     VKQPAISNYEFVHYEGPDRRGIDCALLYDPKQFSVTHSKLVLSTPFEGDTLHLTRGFLI
                     VDGQLAGERVCVIVNHWPSRGAKSPVRVHAARQVKALKDSLMRSDKKLKLIVMGDMNDD
                     PMDESMKVLGARKYPKQVKKGEFYNPWWETLEDKGVGTLLYRGKWNLFDQIVISKPLLK
                     AKKGLRYDHNEVFIRDYLIQQDGKYKGSPLRTHGGRTWLNGYSDHLPTIIYLKN"
     CDS             21148..21399
                     /locus_tag="ctg23_253"
                     /transl_table=11
                     /translation="MKKGIHPENYRPVVFKDMSNGDVFLSRSTCNTKETIEFEGETYPL
                     VKLEISSTSHPFYTGKSKLVDTAGRVDKFMSRYGNRKK"
     CDS             21581..23107
                     /locus_tag="ctg23_254"
                     /transl_table=11
                     /translation="MKRLATLFILTILVATAGFAKPKKYKDLSGNIAVKGELTKEYRQS
                     PAGTPVIIRRVVKMKNPGESSNNICYAVEMNGIQETIPLNEMGHIAISAPQTDREFWQQ
                     IYLKNHLYEYFSDRGYKHKLRQEIDEECLEYLDKLNEIAYQEDYIVSYVQGVFSKLNAT
                     TIDSNRGESLNIRIIQSPEPDAFMLPNGSMVISTGLLCTLDSEDELAAVIACELGHFVL
                     DHQVNNIYRAERRAKRAAFWADVFATTASAALDVAYWDDNEDAYAVSLVADIGAIASLL
                     SIPATDRLGMKYKTSQEISSDRLARQLLAFKGYNPDGIASALGKIIGYYNLHQRNKDIP
                     RYGSIGNLQKRIEKAGESHSLSARPYLRTTSDVVSFNASMNYANKRYKETARLIRKNID
                     NRLATDNDYIILVKAEMALSNTEEVNNRCLAMLDKAQEMAGTSPNLDIYKQKILLLMRM
                     NKQAQAADILKEYITLLSAYEGQGIEGTEKEWTNKEIGWANQMLDRISRI"
     CDS             complement(23199..24287)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GCV_T"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GCV_T_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_255"
                     /sec_met_domain="GCV_T (E-value: 2.9e-95, bitscore: 313.3,
                     seeds: 72, tool: rule-based-clusters)"
                     /sec_met_domain="GCV_T_C (E-value: 6e-24, bitscore: 78.7,
                     seeds: 348, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTTPFTEKHISLGAKMHEFAGYNMPIEYSGIIDEHLTVCQGVGV
                     FDVSHMGEFWVKGPHALDFLQKVTSNNVAALTPGKVQYTCFPNDNGGIVDDLLVYHYEP
                     EKYLLVVNASNIEKDWNWCVSHNTEGAELENASDHMAQLAVQGPKAIQTLQKLTSINLS
                     DLPYYTFTHGEFAGEKDVIISNTGYTGAGGFELYFYPEAAMKIWDAVFEAGAEFGIKPV
                     GLGARDTLRLEMGFCLYGNDLDDTTSPIEAGLGWITKFVEGKNFTNRPMLEKQKAEGTT
                     RKLVGFEMIDRGIPRHGYELYSTDGTAIGVVTSGTMSPTRKIGIGMGYIRPEYSKVGTE
                     ICIDMRGRKLKAVVVKPPFRKQ"
ORIGIN
        1 tttcaaagca agaaaaacat tgtcctgact ggtataaaga tagtgttgtc catattgatt
       61 gacatctgac aagtaacgga gcttcaacga atgtatagga aattcattgg catattcctt
      121 cttcttatga aaagaatatt ccagttcggc aagtcctttt acacgatggt cgcgaaaacc
      181 gtatgccata taccccctac cgaacagatg cggattgagc catgccgtcg tcataccgcc
      241 ggcacgcaag cgcacccctt ccagtgtatt tccgctgatg gtggtattca tcataccgat
      301 atagaacaaa ggttcttttt ccttcggagc gggaatatac cccgtgaaca gcaccttcaa
      361 cactttctcc gtccagaaat aaacgggata gctgcgcaac tgggccatca tcttgtccac
      421 cgaagtttct ttcttgctga cttccacctg gcggttggca tcccaatatg cttccgaata
      481 gccggaagcc gatgtctctt caatcacctt ttccggtttt cggaaagcct gcagagcctt
      541 gtcatccggt tcatactgat aatttctgta atacacatcc cgcttggcat aaataccgtc
      601 actattgtcc accaacttga actccgtagt gatactctca ttgagcaact gcctcgtacc
      661 gtcctccgcg cggtcaaaat tctgttcaat cttcatgtag tccacaaagt tcagatttat
      721 tttctgagga aagttcatga cggtacgctt tacaaaatag gtactgtcca gcatgacgta
      781 taaatgtccc gtaaaaccga acgactcgga gttgaaaggg acaaatgtca agtcaacaca
      841 aggctttccg gcaacggtaa gcgtatccat cagataatat ttgtagaaag acggcccaag
      901 ggaggaaagc ggactgacaa acttattggt gaacaaggtg atgttgttct cataaaggtc
      961 tacatcggtc atggtgacac tgatagcctg ctccataccc tgctgggaaa gcatttcgtc
     1021 cactcctgcc tgcctgcggg cggtgaccca ctgtttccgg ctatgcggag acttgcggta
     1081 atagtctgtg gcaagcaact cacggttgga gatggccagt accggcctgc cggtaacggc
     1141 agaggtatcg acataatccg tcagaaactt gaacttacgg taaagccact tctgttgctt
     1201 caagctgtcg aagttattga tggcaaaagt catcttttca tagcggtcac gtttccagaa
     1261 gtcgcgttcg tcgggcgagt agtcatcccg atgctctatc atcttgcgta caaactccac
     1321 tgcgggatta tcctttttct tataccgttc acgtttcggc ttcaccacca cctcatccag
     1381 tgcataagtg gctggcgaaa gggcaatatt gaacttagaa gactttgcag gatgaatcag
     1441 ccggacatat tcattatatc ccacggccga aatgaccagc gtggcctccg ggcgataggt
     1501 cttgaaggaa aaacggccgt tattgtccgt catccctccc tccgtagttc ctttcagata
     1561 aactgacgta taaggcaacg gctccttcgt caacgaatcg gtgacaacgc cttgcaccat
     1621 atattgtgct ctcaatggaa gagtaaccag ctggataagc agaaataccc taaaaaacaa
     1681 cttcatacct tgttttacct aatttggatg gcaaaggtac ggaagaaaac tttttcttaa
     1741 agttcggttt tacggaataa atgttctaaa aaactccttt tgtacaaaac acttcccgtt
     1801 aaaagccgtt gtatagcgaa acgacgctcc agaaagcatc ggaacaacca atatataacc
     1861 taaacaactt gattatggaa tggattttca accagctcag ggaacgcccc gaacttgcca
     1921 ttttcctcac tatattcctg ggattctggc tggggaaact gcgtatcggt aagtttacgc
     1981 tgggcacagt gaccagtgta ctgcttgtag gcgtactggt agggcaactg aatatagccg
     2041 taccgggtcc gataaagtcg gtattttttc tgcttttcct ttttgccgtg ggctataaag
     2101 tgggtcccca gttcttccgc ggactgaaaa aggacggatt gccccaagtg ggctttgccg
     2161 tactgatgtg tgtatccgta ctgttagtga cctggctgct ggcctgatga tgggctacaa
     2221 tgccggtgaa gctgccggac tgctggccgg ttcgcaaacc atctccgccg tcatcggagt
     2281 ggcagaagac accatggcca atatgggact ggacgaggcc caacgacaaa gttacgtcaa
     2341 catcattccc gtatcctacg ccgtcaccta cattttcggt acggcaggct cggcatgggt
     2401 cctatcatcc attggtccca agatgctagg cgggctggaa aaggtgaaag ccgcctgcaa
     2461 ggaactggag gcgaagatgg gcagctctct ggctgacgaa ccgggattca tgccggcggc
     2521 acgccccgtc actttccgtg cctaccgggt cgaaaacgaa tggttcaaga atggaaagcg
     2581 ggtgattgac ctggaagtct acttccggca gcacgacaaa cgtctatttg tggaacgcct
     2641 ccgcaaatcc ggagttgtgg tggaagtcag catgaacata cagatagagc cgggagacga
     2701 agtagtgcta agcggacgcc gcgaatacat cataggcgaa gaaagctgga tagggccgga
     2761 agtacaagat gcccagctcc tggattttcc tgccgaaaag ttaccggtta caatcacacg
     2821 caagacggtt gccggcaaga cggttgcagt tatccgaagg gaaaagttca tgcacggtgt
     2881 cagtatccgg agcatcaagc gcgccggaat atccattccc gtgctggcac aaacggtagt
     2941 agatgccggc gacgtcatcg aagtggtagg taccaggcag gaagtggaag cagcagccaa
     3001 acgtctgggg tatatagacc gccctaccaa ccagacggac atgatattcg taggcctggg
     3061 tatccttgtc ggaggtttgt tcggagcact ttccgtccat atcggcggca tccccatcag
     3121 cttgagcaca agcggcggcg cattgattgc cggcttgttc ttcggctggc tccgcagtaa
     3181 gcaccccacc ttcgggcgca ttcccgaacc ttcgcaatgg gtgttgaaca atgtcggtct
     3241 gaacatgttc atcgcggtag tgggcatttc ggcaggtccc agtttcgtgc agggcttcca
     3301 cgacgtaggt atcagcctgt tcctggtggg agcagccgcc accaccctgc cgctgattat
     3361 cggcttgctg ctggcaaggt atgttttcaa gttccatccg gcactggctt tgggcgtctg
     3421 cgcgggggca cgtaccacta cggccgcttt aggcgcggtg caggatgccg ttgagagtga
     3481 gacacctgct ctgggataca ccgtgaccta tgccgtgggc aataccttat taataatatg
     3541 gggtgtagtc atcgttttgc taatataaga cgattctgta ccaatgctta ctaatccgga
     3601 gcattcaaag aattattgcc ggaaatgcaa gcgactatat acccattcac taatagctat
     3661 tcgtccgaca gctgtcggac gataattcaa cagttgtcgg acgatgattc aacaactgtc
     3721 ggacgaaaag gaaacatata tcggacgatt aatttcaagc aaggaaagaa atagtatacc
     3781 gcatgaacag agattattcg ccgaatgact gaaaacaata aataacgaac ctaaacttga
     3841 gcttatggat acaaaacttt tagaaaagaa aatggaatct atcagtcctt tcgaactgaa
     3901 gaaccgcctg atagacatgg cagacgagag tctgaagaaa ccgcccgtac catgctgaac
     3961 gcagggcgcg gcaaccccaa ctggattgca accgctccac gcgaagcctt cttcctattg
     4021 ggaagcttcg gcctggaaga gtgccgccgc atcatggatt tgcccgaggg cattgcaggc
     4081 atccccgaaa aaaaggcatt gcctcccgct tcgaagcctt cctgaaaaag aacaataacg
     4141 taccgggcgc caaattgctg gaacaaacct acaactacct gctgatgcag catgccgccg
     4201 accccgacag ccttgtacac gaatgggccg aaagcattgt aggcgatcag tatcccgtgc
     4261 ccgaccgcat ccttcatttt acggaaatcc ttgtgcaaga ttacctttcg caagagatgt
     4321 gcgacaaccg tcctccccgg ggtgcctatg acctgtttgc caccgaaggt ggaacagccg
     4381 ccatgtgcta catcttcgac tccctgcagg aaaacttcct gctgaacaaa ggggacggca
     4441 tcgtcctcat ggttcctgcc tttaccccct atattgaaat cccacaactc agccgctacc
     4501 agtttcgagt gaccaaaata catgccaacc gcatgaataa cgaagggatg cacctctggc
     4561 agtacagcga cgaagacata gaccgcttga aaagccctaa aatcaaggcc ctctttgtca
     4621 ccaatcccag taatccgccc agctacacac tcagtccgga tacaatggcg cgcatcgtga
     4681 gcatcgtcag gaatgacaac cctaatctga tgattattac agacgacgta tacggtacat
     4741 tcagtccaca cttccgttcg ttcatggcag aaattcccta caatacgctt tgcgtctatt
     4801 cattctccaa atacttcggt gccaccggat ggcgcaatgc ggtcattgcc ctgcacgaat
     4861 tcaacctgtt cgacaagctg atagccaaac tgccgaaaga gaaacgggag attctgcacc
     4921 accgctactc caccctcact ctggaacctg aaaaactgaa gtttatcgac cgtatggttg
     4981 ccgacagccg tcaggtggca ctgaaccata ccgccggact gtcattgcca caacagatgc
     5041 agatgggcct tttcgccgcc tttgccctgc tggacaagga aaacaaatac aagcaaaaga
     5101 tgcaggagat tatccgccgc cgattgcatg ccctttggga gaataccggt ttcacgctga
     5161 cggaagaccc gttgcgcgta ggttattata cagaaatcga catgctggtt tgggcaaaga
     5221 agttctatgg ggacgacttt gtagaatatc tgaaacgtac ctacagcccg ctgaacgtag
     5281 tcttccgcct tgccaaagaa acctctctgg tgctgctgaa cggcggtggt tttgacggcc
     5341 ccgaatggag cgtacgcgcc tcactcgcca atctggacga gaaagactat gcaaccatcg
     5401 gccaaggcat caaaaagata ctggaggagt atgcaaaaga attctttaaa aatggaaagg
     5461 cgaaaggtaa aaattgaaaa ttgaaaggtg aaaggtaaaa ctttcaaatt ttaattaaat
     5521 agtatacgga agcgggtcaa tccatcgctg taggtacgca gggagaacgt gcaaccatga
     5581 cggctcaaaa cttcccggat aaacaccagg ccaattccct gcccgttcgg cttggtggaa
     5641 aagaaggggc tgaagagttt agcttcggtc tctttactta tccccggacc attgtcaacg
     5701 acttcgacag aagcgggggc agtggtcctt actattatct caccttgctg tccgttttct
     5761 ccggcgtccc cctctatact ttcggcggca ttcttgatga tattcacaag cacctgctca
     5821 aaaagagaag catccatacg caccattccc acctccgggt cgcattccag acgtagctct
     5881 atattgcggt cattgcacat tccttccatg aaacgcttgc acatggacac caactcattc
     5941 agttggacgg gtgccagggt aggttcaggt atctttacca catctgcaaa acgggtaatg
     6001 aaacggctca tcgagaaaca acgctccgta cagacgcgca tcacgtcgca gatgtcctcc
     6061 atatcatctt ctgtagaaag tgcctgctcc actgtatcga gtgtggaagt gatgcccgca
     6121 gtggtattgt tcacttcatg agctatcatg cggattacct tttcataggc acgcttctcg
     6181 gcacgcatca cttcttccgt catacgctct atcaagaaaa aaggatgttt gaaccctctg
     6241 tcaataaaag aagaatgggt gcatttataa atattcgcat cattgagacg gaccaccgcc
     6301 gtctcgtctt tgggaataga cgaaagttcg gcagccaacg gggagtccat ctggtccagc
     6361 cgttttgtca tcgcctcctc catacggaca ccgagcatct ttaccgccat cggattcagt
     6421 tgcgacactt catcgtccat tgtcaggata ataaccccca ttggagatgc ctgaatcaac
     6481 aaatccaaga agtgattctg ctcgcgcatg cgcaaccgtt cattcttgag ctgctccatc
     6541 attcggttaa agatattcac aatgcggtct gcctcgtact gccctacccg gctgagacga
     6601 ctactgaaat cctgctcgcg cagcaactcc ataccgctgc ctatggtgtt catcggcttc
     6661 actatcttat tatagaatac tatcagatag ataaggataa acccgatgag cccctccaat
     6721 acgtacagat acaaagaagg ctttccactc agcagatata ccagcattcc acccagaccg
     6781 agcagaaaaa ggacgagtat gaagaaaaag aattttatgc gcacgggact tgaatattat
     6841 atttttccaa acgtctgtaa agcgcagcgc ggctgatgcc taatgacact gccacttgac
     6901 tgagattccc tttatgctgt tccaacgcct gcaagatagt ctgccgctct atttcatcca
     6961 aggtcatacc tgcaaaagaa gtaccttcgg cagctttggc cggttcgtcg tgacgcagat
     7021 attgggcatc gaaatccgtg gcatccagca ccggcttgcc gctgaccaga atggtacgct
     7081 ccaccagatt cttcaactca cgaatgttgc ccggataagg caggcgggaa aggaaattca
     7141 gagcgtcggc cgagaaatcc gtacgcggca agccgttcac ctctgcctga cggtcggcaa
     7201 aatgacgtgc cagcaaaggt atatcctcac ggcgctcccg caaggagggc agttttacgg
     7261 taatcaggtt gatacggtaa aaaaggtctt cacggaaagt acgttcggac accatcttgc
     7321 ggaggtctgc attagtggcg gacacaacgc gcacatcgac tttgcgggga cggctatcgc
     7381 ccagcacttc gaatgtctgg tcttgaagca cgcgcagcag tttcacctgg caggaagggt
     7441 cgaggtcacc aatctcgtcg aggaagatag tacctttatt tgccatttca aaacgcccta
     7501 tacggtcggc gctggcatcg gtaaacgccc ctttcttatg gccgaacatc tcgctctcga
     7561 acaagctctg cgagatgcca ccaaggttca ccttaacaaa gggctgcttc acgcgttggc
     7621 tgttgatatg gatggcttcg gcaatcagct ccttgcccgt tccgctttcg cccgtaatca
     7681 gcaccgaagc attggtacgg gctatgcggg ccactgtgtt caacacttcc atcaaccctt
     7741 tggacttacc tataatatgg ctgcgattca atgcggtagt ctgttcttcc ggcacctctt
     7801 tcggggcggc cgtaagctca agggccgtct cgatgcgctg caaaagagca gcattgttcc
     7861 aaggcttggt tatgaaatcg aatgcgccgg cctgcatacc ctgcacggca agctggatac
     7921 ttccccatgc cgtcatcaaa ataacgggca catcgggacg gaacaccttt acctgcttca
     7981 ataaggtaag tccctcttct ccggtagtgg aaagagtgaa gttcatatcc atcaaaatca
     8041 aggcgggagc ttcggccctc actatgtcca tagcttcgcg aggacttgga gccgttttca
     8101 cctcatatcc ggcacgcttc agcataaagc tgagggaaga gcgcacagca ctatcgtcgt
     8161 ctattatcag tatcataaaa attgtagttt gtttcccgca aaaataagta aaaaagcaga
     8221 gttatgaatg ataagttata agttatttac ctataatatc gcatatacgg tacttttacc
     8281 ggcaaataac tcataactta tcacttgcaa cccgtcgact tatcctctta ccacctcttc
     8341 aaaatcagct tccaattccg tatcgcgttc aaaatcccaa agggtcaagc tgcggagctg
     8401 atagaagtaa taccaatagt agtacagctc tgaaatatgc ttttgacggg cttcgtcttt
     8461 agagttctgt gcatcgttca ggtccagggt gctgatttta cctatcataa aggtctctac
     8521 actggtcttg taacgcttct cagcaatgac atccgcctct tcggctatgt ccagctgttg
     8581 cgcctggttg ttgaagttag ccaccagcaa aaagatgtcc tggttaaagt ccatctgttc
     8641 ctgacggatt ctggacaaga ccacttcacg gttgctcttt gccaccctta ccttgccgcg
     8701 gcgcttgccc cagtcaagga taggaatctt gacgcctacc tgcacaatct gattatcaag
     8761 caagtcccgg taggctgaag agaattcatg gttctgcccc gtatagccca cactggcaaa
     8821 gaggtcgatg ctgcgcaagt ttccgcgtgc cgttgccact tcataatcag cttcgagctg
     8881 gcggcggcga atgttctgtg caaaggagtt gcgttccagt gccttgttca gcacacggtc
     8941 atactccatc tttatatcgg gaacagtggc gggcaacacc ggattcaggc tttcctgctc
     9001 ggacaccccg aggaaagaac ggagctggaa catttttgca ttcaggttgc tctctgcctc
     9061 agtcacgtcg gccttgccct gcaatgaatt cagtttaagc tgcaacaaat cattctcgga
     9121 tatctgtccc attttacgtt tggctatggc cacttcataa aggcggtcgg cattcgtctt
     9181 gttctgcatg gcggtagcga gcgattcttt ggccagcagc aactcaaaga aataagtgat
     9241 ggttttcatc gtcacctctt ccgtagctga aatgaactcg gcctttgcct cggcatagcg
     9301 tacgggctct atacggcggt tccacttcaa ggtattcact ccgaagaccg gctgcgtcaa
     9361 ctccaggctc acggggactg acatgaactg cttcgctcct ccggaaccca gttgtttgag
     9421 ataatccagc gaagaagtca gtgacagctt accccccgta aaccaaatgt tctggtctac
     9481 cgaaagctgt ccggacagcc ccagtgtatt gttgcgaaca aagctatagg agccgtcgga
     9541 attctggtag gtactgtagg acttgttata gttgggtagt gtaccggtga aattcacttc
     9601 cggcaacaag tccgcacgga atgtacggta ttcccaatac gcggttttca attcattcaa
     9661 tgccacagca gcatccacag actgcgtacg ggccagtaca atggcctccg acagcgtaat
     9721 attgcgttca tgtcccaaag tatcattctg cgccatggtt gccaacggca tcaaaaaaca
     9781 aactgcaagt aaaatattct ttttcatgtt caatctttaa aattgtcgca aacagaaaag
     9841 caaagagtgt gccaagtggc cggaaaggtt tcatagaggg gtaagtgttc attttcggac
     9901 agtggggatg tccgttagcg gacgatatca agaaaacaac cggtctctat ctaaagtctg
     9961 aaaaaatcct tctaaagttc aattaaccat taattaattg atgaaaaatt tctttattaa
    10021 ggaagaattc tctttctttg tgctgcttta tacctttatt aaaaaggata caatactaac
    10081 attaatttat atagttatga agatttcaca cattgagcat ctgggcattg ccgttaagag
    10141 cattgaagaa gcccttccgt actacgaaaa cgttttaggt ttgaaatgct acaacatcga
    10201 aaccgtggaa gatcagaaag ttagaaccgc tttcctgaaa gtgggcgatg taaagatcga
    10261 attgttggaa cctacttctc ccgaaagcac aattgccaag ttcatcgaaa agaacaacgg
    10321 taacggtggc atgcatcatc tggcatttac cgttgaagac ggagtggccg gtgcgcttgc
    10381 cgaagtcgaa gaaaaaggta tccgccttat agacaaagct ccccgcaaag gtgcagaagg
    10441 tctgaacatt gcattcctgc atccgaagtc aactctcggt gtcctgaccg agctttgcga
    10501 gaaaccggaa taagcaagac tgtaaaatca tcaaatcata aattgtataa acacttaaag
    10561 aatataaatt catgagtaat caacttgaaa agattaaaga gcttatagac cgccgcgctg
    10621 cagcacgtct cggtggtggt gaaaaagcga ttgcaaagca acacgagaag ggtaaatata
    10681 cagctcgcga gcgcatagcc atgcttctcg acgaaggcag tttcgaagaa atggacatgt
    10741 tcgtagaaca tagatgcacc aacttcggca tggaaaagaa acactacccc ggtgacggtg
    10801 tagtaaccgg ttgcggtaca atcgaaggcc gtctggttta tatcttcgca caggacttca
    10861 cagtttctgc cggttcactg tccgaaacca tgtctctgaa aatctgtaag attatggacc
    10921 aagccatgaa aatgggtgct ccgtgtatcg gtatcaacga ctcgggcggt gcacgtattc
    10981 aggaaggtat taatgccttg gctggctacg ctgaaatctt ccaacgtaac atacttgctt
    11041 cgggtgtcat tccgcagatt tccggtattt tcggtccttg tgccggtggc gccgtttact
    11101 ctcctgcctt gacagacttt actttgatga tggaaggtac atcctacatg ttccttaccg
    11161 gtccgaaggt agtaaagact gtaaccggag aagacgtaag ccaggaaaac ctgggtggcg
    11221 cgagcgttca ctccaccaaa tctggtgtta ctcattttac tgcacagaca gaagaagaag
    11281 gtttggctct tatccgcaaa ctgttgagct acattcccca gaacaacctg gaagaagctc
    11341 cctatgtaga ctgtacagac cctatcgacc gtctggaaga ttccctgaac gacatcattc
    11401 ctgataaccc gaacaagccg tacgatatgt acgaggtaat tggtgctatc atagataatg
    11461 gtgagttcct cgaaatccaa aaagattatt caaagaatat cattattggt ttcgcacgtt
    11521 tcaacggaca gtccgtaggt attgttgcca accagccgaa gtatctggca ggtgtgctcg
    11581 acagcaacgc atcccgcaag ggcgcacgct tcgtccgttt ctgcgacgcc ttcaatattc
    11641 ctatcgtatc attggtagac gtaccgggat tccttccggg aaccggccag gagtacaacg
    11701 gcgtcatcct gcacggtgcc aaactgctgt atgcatacgg tgaagctact gtacccaagg
    11761 ttaccatcac actgcgtaaa tcctacggtg gttcgcacat cgtgatgagc tgtaagcagc
    11821 tgcgtggcga catgaattat gcttggccta ctgctgaaat cgctgtaatg ggtggtgcag
    11881 gtgctgtaga agtattatat gcccgcgaag ccaaagagca ggaaaatccg gctcaattcc
    11941 tggctgaaaa agaggctgaa tacaccaagt tgtttgccaa tccttataat gcagctaaat
    12001 atggctacat tgatgatgtt atcgaaccgc gtaacacacg tttccgcatc attcgtgccc
    12061 tgcaacagtt gcaaaccaag aaattgacta acccggctaa gaagcatggt aatattccct
    12121 tgtaatcaag cttttcacac taaaacaaga acgattatga ataaaacaaa aatcggaata
    12181 ttcctttcat tgatgctggt gttgggcttt tgctcttctt gcaaagaaca gaaatcgaac
    12241 aacaaactgc tgctgaatga agtgctggtc aacaacgaga gcaactatca ggatgactac
    12301 ggtgtgcaca gcgcatggat tgaaatattc aacagatcat acggcagcgc cgaccttgca
    12361 ggttgctatc tgaaattcag cagccagccg ggtgatactg ccagttattt cattcccaaa
    12421 ggtgacgttc tgacactcat aaaaccacgt cagcatgcac ttttctgggc tgatggagaa
    12481 ccaagacgcg gtacatttca tacgaacttc aaactggatg ccacaaatgc caactggatt
    12541 gggttgtatg attccggcaa gaaattgctt gatcaagtca tagtgcctgc cggtacttta
    12601 aaagccaacc aatcctatgc ccgtgtcagt gatgcagccg accaatggga agtaaagggt
    12661 ggaagcgaag ataaatatgt cactccgagt accaacaaca agactatcga cagcaatgcc
    12721 aaaatggaaa aattcgaaga gcatgacagc gtaggtatcg gtatggctat ttctgccatg
    12781 agcgttgtat tctgcgggct gatattactc tacatctcct tcaagattat aggtaaaata
    12841 tcagttaacc tcagcaaacg caatgccatg aaagctaaag gtattactga taaacaagaa
    12901 gcaaaagaga aacaactggg gcaggctccg ggagaagttt ttgctgccat ttcaatggcc
    12961 atgcacgaat tccaaagcga tgtacacgat gtggaagaca cgatacttac cattacccgt
    13021 gtaaaacgca gttactcacc gtggagttca aagatttata cgttgcgtga gactcctcac
    13081 aaaaagtaag tcacccataa taaaataaaa cgatgaaaga atataaatat aaaattaacg
    13141 gtaacgtata taaagttgcc attggagata ttgaagacaa catcgctcat gtagaagtga
    13201 acggtactcc ctacaaagtt gaaatggaaa aagcaccgaa ggtagtcgtt aaaccggtag
    13261 cacgtccggc agccacatcc gctcctgctg ctcctgctac tccggtagta aaaccggccg
    13321 ctgcttctac cggcaagtca ggtgtaaaat ctccgcttcc cggtgtaatc ctcgatatca
    13381 aagtaaatgt cggcgataca gtaaagaagg gacaagttat catcattttg gaagccatga
    13441 agatggaaaa caatatcaat gctgataaag acggtaagat tacagccatc aatgtaaaca
    13501 aaggggactc tgttctcgaa ggtactgacc tcgtaattat tgaataatat gggagaattt
    13561 atcacatttt taggaaacaa ccttgccgac ttctggactt atacaggttt tgccaatgca
    13621 acggtaggac atgtggtaat gcttctggta ggtttgtttt tcatatactt ggctgtagcc
    13681 aaggaatttg agccgatgct attaattcct atcggtttcg gtatgctgat tggtaatata
    13741 cctttcaata tggaagccgg attgaaagtt ggtatctatg aagaaggttc cgtacttaat
    13801 attctgtacc agggagtaac ctccggttgg tacccgccac tcatattcct gggtatcggt
    13861 gccatgacgg atttctctgc tttgatatcg aaccccaaat taatgttggt tggtgcagca
    13921 gcccaattcg gtatattcgg tgcttatatg attgcccttg ccataggatt tgacccgatg
    13981 caggctggtg caatcggtat cattggtggt gccgatggtc cgactgccat cttcctctct
    14041 tccaaactgg ctcctaactt aatgggtgcc attgcggtat cagcctattc atatatggca
    14101 ttagtaccgg tgatacagcc gcctattatg cgttggctga ccagtaaaaa tgaacgtctt
    14161 atccgtatga aacctccccg tgtggtttca catacggaaa aagtaatgtt cccgattatc
    14221 ggtttgttac taaccacatt ccttgtacca tccggtctgc ctttgctggg tatgctgttc
    14281 ttcggtaatt tactgaaaga aagtggagtt acacgtcgtc tggcaaacac agccagtggt
    14341 ccgctgattg ataccattac tattctgctt ggtttgacag taggtgcttc tacgcaagca
    14401 tccgagttct taacccttga ttcaatcaag atattcggtc tgggcgcctt atcatttgtc
    14461 attgccacag catccggtgt catcttcgtg aagattttca acctcttcct gaagaaaggc
    14521 aacaagatta atccgttgat cggtaatgcc ggtgtatctg ccgtacccga ctctgcacgt
    14581 atctcccaag tagtaggtct ggaatacgat cctaccaact atctgctgat gcatgccatg
    14641 ggcccgaacg ttgccggtgt aatcggttcc gctgtagcag caggtatcct gctgggattc
    14701 ttaatgtaat acatttattc attccgttat ccggcttgaa ttctgaacta ttttagagcc
    14761 ccttcatttt tggaggggct ttttcgttaa tctatctaaa acagattacg attatttcgt
    14821 aaatacattc tttttagtaa cttgcagtca gtttaacctc atataaatga tatactgtat
    14881 gcgaaagctt tttatctcct tatgtttcag tgcatgctgt tcgcttctgg cggcacagac
    14941 cacaaatccc attcaagagg cgatggccaa ctacgattat gaaacagcct tgatgctgat
    15001 cgatcaagaa accccgaccg tccccctact ctaccaaaaa gggaaagcgc tgaaaggctg
    15061 ggcaataacc ttgaagctct gagcgtattt caggaagtcg tagctcagga ttctctcaat
    15121 ccccgggcat acattgaagc tgccgaatgc tgcaaatcac ttgccaaata tagcgaggca
    15181 ctggattact accagaatgc gctccacata aatccggaca ataaatacgc acgcatccag
    15241 tatatcagtc tgctgatgaa catgaagaga taccgtgagt ctctaaagga aagcaacctg
    15301 ctggcagaaa gggacagttc cgcctatgta ctacacctta gagccgaaag tatggggcaa
    15361 gtctatgaca acacagaaat catgcatgtg atagatgcct acctggacat acagaaaaga
    15421 tatcccaatg attacctgtc tgctgccaaa ctcggcaaca tctatgtagc aggccaccag
    15481 tatgaagacg ccataagcat aacggagaaa taccgttcca tagactccac caacgtcctt
    15541 gtgaaccgca tcaatgccca agcctattgc ctgaacaaag attaccccaa agcaatagaa
    15601 agatatgaac aactgttaca ggaaaaagac agttctttcc aaacctgctt ctacgccgga
    15661 atcagctatt atgccctcga agacttctac ccagcacacg acctgctgga aagggctctt
    15721 aaagatgaca ataccaacat caacgttctc tattatctgg gacgcgcctg ctccaagaca
    15781 tcatggaaag aggatggagt gacttatctg gaaactgccg taagcctcgc catgcccagc
    15841 gacagtgtca tgtcccgcct atatgtgggg cttgcggact gctacaagat ggcatttcaa
    15901 tacaccgacc aggcgaatac ccttctgaca caatacgaaa aatacgaccg gcagaaacac
    15961 aaactgctct acgacgcagc ctttatctat tattactatc tgaaagatgc gtccaaagca
    16021 gagagatacc taacggccta cctgaaaacc cgtccgaaaa acagcaagga caaagtgcag
    16081 gaagtagatg cggacggagt tcccatcatc ggagaagaca accgatacaa tgccgccgaa
    16141 aactggctga aggacatcag agaaaagcgc aagaaagagg acttcttcaa gggaaaggtc
    16201 gataccgcca gcgtaacccc catcaaatag cccaatgaaa acgtttgcat aatataataa
    16261 agtacagtaa cggagaaaga ttaactttct cgttatttgt tttaaattag cgcaaaaatt
    16321 aaccgtaaag ttactatcat gaaaaaagta ttcttaatct tgggaacact cttactctcc
    16381 ctcagtacgt atgcagctat gaatgtgaac aaaatcgacc ctccgttttg gtacaccggc
    16441 atgcagaacc cggaactcca gctgatggtc tatggcgaag gcatcggcaa cgcggcagta
    16501 tccgtcaatt atcctggcgt ctcattgagc agcaccgtca agctggaaag caacaactac
    16561 ctcctggtct atctgaaact ggacaaggat gtaaaacccg gcaaattcaa cctcaccttc
    16621 actgaaggaa aaaagaaact cgtaaaggaa tatgaactga aggcacgcaa caagaaaggt
    16681 tgcgaacata aaggtttcga cgcctccgac gcactgtacc tgctgatgcc cgaccgcttt
    16741 gccaatggca atccggacaa tgaccagatt gcgggcatgg ccgagtacaa gatagaccgc
    16801 aatgacccca atgcacgcca cggcggtgac cttgccggca tcgaacaaca cctggactac
    16861 ttctccgacc tcggcgtcac agcctctggt ttactccggt actggaaaac aacatgaccg
    16921 gcggttccta tcacggctat gccaccacag actactacaa ggtagacccg cgcttcggta
    16981 ccaacgaaga atacaagcaa ctgattgaaa aagcccatgc acgcggcatc aaaatcgtaa
    17041 tggacatgat tttcaaccac tgcggcgtag agcatgtatg gattaaggac atgccctcca
    17101 aagattggtt caacaacccc gaccacgaaa acaacttcgt gcagacctcc ttcaaactga
    17161 ccccgcacgt agacccttat acttcccagt acgatgccga ccagatgaac gacggctggt
    17221 tcgtaccttc catgcccgac ctcaaccaga agaaccctca cgtttaccgc tacctggtac
    17281 agaacagttt ctggtggatt gaattcgcca acatcgacgg catccgcatg gacacttacc
    17341 cgtatgccga ctatgatgcc atgagcaact ggatgaaaga gctcaacgaa gaatatccca
    17401 actacaacac cgtgggcgag acctgggtta ccgaacccgc ctacaccgcc tggtggcaga
    17461 aggattccaa gctatcagcc cccaagaaca gtaacctcaa gaccgttatg gacttcagct
    17521 tctttgacaa gataaacacc gccaagaatg aacagaccga gacttggttc aagggactgg
    17581 accgcatata caataacttc gtatacgact tcctctaccc caaccccgct tccgtactgg
    17641 cattcatcga aaaccacgac accgaccgct tcctgggcga aggcaacaac cttccgatgc
    17701 tgaagcaagc ctctaccctg ctgcttacca cccgccgcat tccgcaactc tactacggaa
    17761 cggaagtcat gatgaatggc gtgaagagca agagcgacgg ctatgtccgc aaggacttcc
    17821 ccggcggatg gaccggtgac gcaacaaacg cactgacccc agccggacgt accaaaatac
    17881 agaacgagtg ctacgacttc tacaagacca tcctgaactg gcgcaaagga aacgatgtga
    17941 ttgccaaagg cagcatggtg cagttcatgg tacagaatgg tgtttatgcc tacgcacgcc
    18001 agtacgaagg caagacggta ttcgtgatgc tgaacggtac agatgcagag accaccgttc
    18061 ctttgaaatt ctacaaggaa atcctgaaaa acagcaagca gggaaaagat attcttagcg
    18121 gcaaggccat caccttcggt gaagagctga agatgggccc cagagaatca ttagtgatag
    18181 aattataacg cgcactccac acagagagct cattcttgca aatatccctt gcagatagct
    18241 agcagacacc tcgcctgcca gccatctgca agggattttt agtatggaat aggtgtcacg
    18301 gggatatgct tttcaccggt ctcaaatata gctaatctgt tagttcataa cggtgaacac
    18361 tttgttccag tatagagaaa caaagtgttc ggatatgtag aaacaaagtg ttcttacgta
    18421 ttggaacgaa gtgtttttgc atattggaac aaagtgttct ctttattgaa acaaactgtt
    18481 cagttaaggg aaacagactg ttttgttaaa ggaaacagac tgttgtacac gttgaaacat
    18541 ccgcttctga aataagcggc gaacttaacc atcccacaac accggcctat atacaacaag
    18601 tcagcccttg caacatcaat attgcaaggg ctgacgctat attcggatta tctttcgatt
    18661 agtccagttg agccaatttg ttctctgaac caagcacgtt gatgatttta tgcttgtaca
    18721 gtttttccat attgtcacga gccggaccca gatacttacg cgggtcgaat tctgccggtt
    18781 tttcagcaaa tgtcttgcgg atagcagctg tcatagccag acgtgagtca gagtcgatgt
    18841 tgattttgca aacagcagac ttggcagcct tacgcaactg ctcttcgggg ataccgatag
    18901 cagcttccag cttaccacca tacttgttga tagtatcaac ttcttcctga ggaactgaag
    18961 aagaaccgtg aagaacgatg gggaatcccg gaagtttctc cattacagca tccagaacgg
    19021 caaattccag aggaggagga accagacgac cggtagcagg gtcaacgtgg cattgttcgg
    19081 gtttgaactt gtatgcaccg tgagaagtac cgattgagat agccagtgaa tcgcaacctg
    19141 tacgggtagc gaagtcaata acttcttcag gattagtata tgtatggtgt tctgcagaaa
    19201 cttcatcttc tacaccggcc aatacaccga gttcgccttc tacagttacg tcgaactgat
    19261 gagcataatc aactaccttc ttagtcagtg caacgttttc ttcgtacgga aggtgtgaac
    19321 cgtcaatcat tactgaagag aaaccagagt cgatacagct cttgcaagtt tcgaatgtat
    19381 ctccgtggtc gaggtgaaga acaatttcag gatgtttgca acccaattcc ttagcgtact
    19441 caacagcacc ctgagccatg taacgcaaca gagtagcgtt ggcatactga cgggcaccct
    19501 tagatacctg aagaataacc ggagactttg tttcaactgc agccttgatg atagcctgca
    19561 tctgttccat attgttgaag ttgaatgccg gaatagcata tccacctttg atagccttag
    19621 caaacatctc tcttgtgttt accagtccta aatctttgta attaaccatt ttgtttaaat
    19681 tttattgtta gtgaattaaa attctacgca aaagtaatca ttatccttta aagtaaagaa
    19741 cttgagagga ataaaatatc cggctcatcc taccaaatcc attctatttt aaagctattg
    19801 gcttcattta acagattatt gtaatctcta tattacaaac tctttgcatt tatctctgcc
    19861 agccatactt ttgccatcta tacttctatc aacaaaaaag ccggagaaca tgtttgctct
    19921 ccggcatctg tttacacatt attatgtaat actaattttt cagatagatg atggtcggca
    19981 aatggtcact gtaaccgttc agccaagtcc tgcccccatg cgtacgcaag ggggaacctt
    20041 tgtatttgcc atcctgctga atcagataat cgcggatgaa aacttcattg tgatcatagc
    20101 gcaacccttt cttagccttc agcaacggtt tcgaaatgac aatctggtca aacaagttcc
    20161 acttgccccg atagagcaat gtccccactc ccttgtcttc cagtgtctcc caccagggat
    20221 tgtagaattc gcctttcttc acctgcttcg gatatttgcg tgcacccagc accttcatgc
    20281 tttcatccat cgggtcgtca ttcatatccc ccatcacgat gagtttcagc ttcttgtcgc
    20341 tacgcatcag agagtccttc aaggccttta cctgcctggc tgcatgcaca cgcaccggtg
    20401 actttgcccc acgggagggc cagtggttca ctatcacgca gacacgctct cccgccagtt
    20461 gcccgtccac aatcaggaag ccgcgcgtca agtgcagcgt atccccctca aaaggagtag
    20521 aaagcaccaa ctttgagtgg gtaacgctaa actgcttcgg gtcgtacagc aaggcacagt
    20581 ctataccccg tctgtccggt ccttcataat gcacgaactc ataattggaa atggccggct
    20641 gcttcacgag gtcttccagc acccggctgt tctccgcctc tgccacaccg atgaatgccg
    20701 gaccttccgg cactaaatca cgcgaaaggg aacccaacac tttggaaagg ttctgcagct
    20761 tggactcata cttctttgcc gtccattggt aactgccgtc gggcaggaac tcatagtcat
    20821 tcttacctgc atcatgaatc gtatcaaaca agttctcaag attgtagaac gcaacactat
    20881 acagtttccg ttccgcattt tgtgccccca gcgttgccac gcacagccag aaagagcata
    20941 agacaagtag tttcctcata aattcacaag attaagtcct gcaaaaatca gaaataaaat
    21001 gcgataaacc tactaaataa aaataaatct gaatttattt tgtagagtct ccaacttgca
    21061 ctatctttgc gctctgaaaa gaagaccatt acactattta ttaccaaaat agtaacagaa
    21121 tataaatttt taaaagaaaa tatcaaaatg aaaaaaggta ttcatcctga aaattaccgt
    21181 ccggtagtat ttaaagatat gtcaaatggt gatgtattct tgtctcgttc cacttgcaac
    21241 acgaaagaga ctatcgaatt cgaaggtgaa acttatccgc tggtaaagct ggaaatctcc
    21301 agcacttctc acccgttcta cacaggtaag tctaagctgg ttgacactgc cggtcgtgtt
    21361 gataagttca tgagccgtta cggtaaccgt aagaaataat cagtttcaag caaactgaaa
    21421 aaagggagtc tttcactgaa aggttccctt ttttgtttcc gcctcccact gcaggaccga
    21481 taaataggga atctcctatc acagaatagg gaaaaaaacg agaaaggaga aaaacacttc
    21541 cctatttttg tatcatcaaa accgaaaaca tatactaatc atgaaacgac tcgccaccct
    21601 attcatcctg acaatccttg tcgcaacggc aggatttgcc aagcccaaaa agtacaaaga
    21661 tttaagcgga aacatcgctg tcaaaggaga attgacaaaa gagtaccggc aatctcccgc
    21721 cggtacaccg gtcattatcc gccgggttgt caaaatgaag aatcccggtg aaagcagcaa
    21781 caacatttgc tatgctgtcg aaatgaacgg catacaagag accattcctt tgaatgagat
    21841 ggggcacatt gccatatccg ctccgcaaac cgaccgggaa ttctggcagc agatatactt
    21901 gaaaaaccat ctttacgaat atttcagcga ccgcggctac aagcacaaac tgcgccagga
    21961 aatcgacgaa gagtgcctgg agtatctcga caaactgaat gagatagcct atcaggaaga
    22021 ttacatcgtt tcgtacgtgc agggagtgtt ctccaagttg aacgccacca ccattgacag
    22081 caatcgcggg gagagtctga acatacgtat catccagtcg cccgaaccag atgccttcat
    22141 gcttcccaac ggctccatgg ttatcagtac gggcctcctc tgcactcttg attccgaaga
    22201 cgaactggcc gccgtcatcg catgtgagct gggacatttc gtcctcgacc atcaggtaaa
    22261 caacatttac cgtgccgagc ggcgtgccaa gcgtgcagct ttttgggcag atgtctttgc
    22321 cactaccgcc agtgcagccc tcgatgtggc ctactgggac gataatgaag atgcttatgc
    22381 cgtcagtctg gtggcagata tcggagccat cgcttccctt ttgagcattc cggcaacgga
    22441 ccggttgggg atgaaataca aaacttccca ggaaatctct tcagaccgcc ttgcgcgcca
    22501 acttctggca ttcaagggat ataatcccga cggaatcgca tcggccctcg gtaaaattat
    22561 agggtattac aacctgcacc aacgcaacaa ggacattcct cgctacggca gcatcggcaa
    22621 cctgcaaaag cgtatagaaa aggccggtga atcccatagc ctgagtgccc gcccctacct
    22681 acggaccacc agcgatgtcg tttctttcaa cgcaagtatg aactacgcca acaagcgcta
    22741 taaggaaact gcccggctga tacgcaagaa cattgacaac agactagcca cagacaatga
    22801 ctacatcatc ctggtaaaag cggaaatggc actgtctaat acggaagaag tgaacaaccg
    22861 ctgcctcgcc atgcttgata aagcccagga gatggcagga acaagcccca atctggacat
    22921 atataaacaa aaaatactat tattgatgcg catgaacaaa caagcccaag ccgccgatat
    22981 actgaaagaa tatatcacct tgctttcggc ctacgaaggc cagggcatag aaggaaccga
    23041 aaaggaatgg accaataaag agataggttg ggcaaaccaa atgctggaca ggataagcag
    23101 aatatagaga aaggaataac taagaatgaa gaatttgact gcgcgatgat gccgcatgac
    23161 aaattcttca ttcttcttat tttagttatt cattcaaatt actgtttgcg gaacggcggc
    23221 ttcacaacca cagctttcag cttacgtccc cgcatgtcaa tgcagatttc cgtaccgact
    23281 ttgctgtact cgggtctgat ataccccatt ccgataccaa tcttgcgggt aggcgacata
    23341 gttccggagg taaccacacc gatggcagta ccgtctgtac tatacagctc gtaaccatga
    23401 cgggggatac cgcggtctat catttcaaat cccaccaact tacgggtagt gccttccgct
    23461 ttctgttttt ccagcatcgg gcgattggtg aagttctttc cctccacaaa cttggtaatc
    23521 catcctaaac ccgcttcaat gggcgaagtg gtgtcatcca aatcattgcc atacaaacag
    23581 aagcccattt ccagacgaag cgtatcgcgc gcacccagac caaccggctt aatgccgaac
    23641 tccgcgcctg cctcgaacac ggcatcccag atcttcatgg cagcctccgg atagaagtaa
    23701 agctcaaaac cacccgcacc ggtatatccg gtattggaga taatgacatc cttttctccg
    23761 gcaaactcac cgtgggtaaa agtatagtaa ggaaggtcgg aaagattgat ggaagtcagt
    23821 ttctgcaacg tctgaatagc cttcggtcct tgcacagcaa gctgtgccat gtggtcggaa
    23881 gcattttcca attcagcgcc ttccgtgtta tgagacacac accagttcca gtctttctca
    23941 atgttcgacg cattcacgac aagcaggtat ttctccggct cataatgata gaccagaagg
    24001 tcgtctacaa tgcctccgtt gtcattgggg aagcaggtat actgtacttt cccaggtgtg
    24061 agggcagcta cgttattgga agtcactttc tgcagaaagt ccaaagcatg gggacctttc
    24121 acccagaatt ctcccatgtg tgagacgtcg aatacaccga caccctgaca tactgtaaga
    24181 tgttcgtcaa tgatgccgga atactcgata ggcatattat atcccgcaaa ctcgtgcatc
    24241 ttggcaccca gcgagatgtg tttttcggta aacggagtgg ttttcatgga actattagag
    24301 ttatgagtta tgaattatct atttgcttgc tacgagctcg gcaatcttga cgatgacgtt
    24361 catggctttc tccatgttct ggataggcac gaactcatag cggccgtgga agttcaagcc
    24421 accggcaaag atattgggac aaggcaggcc cttgaaagag agctgggcac cgtccgtacc
    24481 tccgcgaatg gcttttacac gaggctctac acctaccgcc ttcatggcgg caaaagcggt
    24541 gtcgatgata tgcatcaccg gttcaatctg ctcgcgcata ttatagtatt ggtcgcgaag
    24601 ttccagagta gcggtacccg gaccgtattc ttcattgatt tttgccacaa gacgttccat
    24661 ctccttcttg cgctcttcaa agcgggtgcg gtcgtggtca cggataatg
//
