LOCUS       c00012_gnlPro..        15011 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PFHDGMJG_12.
ACCESSION   c00012_gnlPro..
VERSION     c00012_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 22:59:15
            Original ID  :: gnl|Prokka|PFHDGMJG_12
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 310510
            Orig. end    :: 325521
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15011
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[320510:323950]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13440
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15011
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15011
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="2"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(33..1586)
                     /locus_tag="ctg12_259"
                     /transl_table=11
                     /translation="MKCKFSLLLFLCVLSLWGQAQSLNLQELVNKKQFQEVVARADSLT
                     PADSADYATMSAIGQAYEGLLRYKEAYLCFSHCLKMDTNNVDALNAVARNAINFGRIAE
                     AKQCYRKVLGTDSMNFYANYQLARLYYQLGDYGRATEHYHILASIEGENPSILTGLADC
                     HIKRGTGPNTMIALSLYARALELNPENVRVASSLINTLLRMGDGQGALQVCDTALFYNP
                     DNSQIRQSKGMALYMTKDYKQADSVYTDLLADGDSSFLNLKYAGAARYMSGHALDGVEL
                     LEKAYEIDSTDVETVMLYGASLGKTYDRKRAYELFDLAETNMQPKKFLVNMLTTFRGDA
                     LERDGRWPEAEKLYYAAWKEDPTQLHFLYKISTQYWDVDPGLFQQEEKLQKTIFSRYTY
                     LTAYMKTDKSQKYLYNYRPFLEAVCEDAFFRNVDEVTMLAPDGKKTKLAVSDLRALVAQ
                     LPQMPEDERLRREKMQEHIKKAREKEKELRKSDAKLDTLALSKEEKEKARKMLKDADLE
                     "
     CDS             complement(1620..3356)
                     /locus_tag="ctg12_260"
                     /transl_table=11
                     /translation="MTPEFAYFLKVNVAFILLYAFYRLFFYKDTFFKLRRTILLAFFGV
                     SLLYPLMNIQDWIREQGPIVEVIQMYSAILPETTITPGNVPQTNWHDLLLPGISYLYWS
                     GVIALSFRFLVQLSSILLLARRSEVTLIRNVRVHLLNKPAGPFSFFRLVFLHPDSHSEK
                     EIDEILVHECTHVSQWHSIDVIICELVCIICWVNPFVWLLKREVRHNLEYLADDTVLES
                     GYDSRSYQYHLLGLAHTNRSVTSLSNNFNMLHLKNRISMMNKKRSRSIGRTKYLIFIPI
                     VGALLILSNVDALARITDELTESTFADVLLPEAILPFPFVGDASPAEKREEYVLSEEGI
                     EAARRARNQVFTVVEVMPEFPGGQGALLKFLATNVRYPESAVKNGIEGRVSCSFVVGKD
                     GAISEAEVIRGVSPELNEEALRVINSMPVWSPGKQRGKAVNVKYTVPVTFRLSGGKKKN
                     SSRIVQRQIKEVDTSGRVFTVVQQMPEFPGGQASLLKYLATRIKYPAIAQENGIQGRVS
                     CSFVVDTDGSLKNIEVIRGIDPSLDREAVRVIREMPKWNPGVQNNMAVAVKYTVPVTFR
                     LQ"
     CDS             complement(3377..3739)
                     /locus_tag="ctg12_261"
                     /transl_table=11
                     /translation="MERLTRQEEDVMRWIWQIEPCFIKDILAKYEEPKPPYTTLASIVK
                     NLERKKYVKAKRYGNTYEYRPLIPQEEYKRTFMGSVVNNYFENSYKEMVSFFAKEQKIS
                     TDELKEIIDMIEKGRE"
     CDS             4348..5238
                     /locus_tag="ctg12_262"
                     /transl_table=11
                     /translation="MLSFILVLLLGGFMPAGNLLASDKEQNPHYITVKNSRDLQAYFRY
                     APDRPIVISGHRGGMLDGYPENCIESFEKTLSYMESFFEIDPRLTKDGIIVLMHDETID
                     RTTTGKGKVSDYTYAELQQFNLVDRNGNVTAFKIPTLKECLEWSKGKTILNLDIKDVPL
                     EVMADFIETEKPVNVMYTVHNASQARYYLDRKLDAMFSCWCKNREEFDNYEKAGIPWKQ
                     VMAYVGPKMKPEQQPLYDALHRNGVMCMISVAPTHDRAKTETEKTAGYRSEISTRPDVI
                     ETDYPYLFQGLDLTK"
     CDS             complement(5489..6604)
                     /locus_tag="ctg12_263"
                     /transl_table=11
                     /translation="MTDKRIYQIGLTMINGVGDILARHLLQALGEAEAVFTEKQQLLGR
                     IPGIGSNIAAEIKRPEILQRAEKELAFIEKNNISCYYLTDTDYPVRLRECPDAPILFYF
                     KGNTNLDATRIISIVGTRNATEYGRELTESLIKDLAKVIPDLLVVSGLAYGIDICAHRN
                     ALYNRLPTVAVLAHGLDRIYPSCHRNTAVEMLESGGLLTDFPSGTEPDRPNFLRRNRIV
                     AGISDCTIVVESAEKGGSLVTADIAFSYGRDVYSFPGRVGDSHSKGCNNLIRQNKAGLI
                     TSADDLLSALCWDIQAGATPVQTELFFAEAETFTSEQNPVLAIMRTRNEIHINELASVL
                     EIPVHQLSMLLFELEINGKVKALPGNLYKLS"
     CDS             complement(6601..7008)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_264"
                     /sec_met_domain="HBT (E-value: 4e-08, bitscore: 27.7,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 6.2e-09, bitscore: 30.5,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYIFKLTDKVRDYECDLQGVVNNSNYQHYMEHTRHEFLESLGE
                     NFGKMHEKGVDGFVSRVEIQYKTSLKSGDSYISCLNVYKKGVKLVFEQDIYRASDNALA
                     TKGIVESVIVENGKLTRGEYFDEMLKRIEHT"
     CDS             complement(7008..8267)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_265"
                     /sec_met_domain="Peptidase_U32 (E-value: 2.8e-68, bitscore:
                     223.6, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNEKDFEIMAPVGSYESLMAAIQGGADSIYFGIEGLNMRSRSSNN
                     FTTDDLRKIVALCREHGIKSYLTVNTVIYGEDLPLMREIIDAAKEAEVSAIIAADVAAM
                     NYANSIGQEVHLSTQLNISNAEALKFYARFADVVVLARELNLKQVHEIYRQIVDQQITG
                     PKGELIRIEMFAHGALCMAVSGKCYLSLHEMNASANRGACMQICRRAYSVKDKDSNIEL
                     DIENQYIMSPKDLKTIHFMNKMMDAGVRVFKIEGRARGPEYVRLVTECYKEAVRAYCNG
                     TFDEKKVAAWDERLRSVFNRGFWDGYYLGQRLGEWSSKYGSGATKKKVYVAKGIKYFDK
                     IGVAEFEMESGNLKVGDEILITGPTTGAVMQTIEEIRVDLKPVDETVKGERFSLKVNEK
                     IRPSDRLYKMEKVQLEKVFE"
     CDS             8648..9679
                     /locus_tag="ctg12_266"
                     /transl_table=11
                     /translation="MKIGTIDLGERPIFLAPMEDVTDISFRLMCKRFGADMVYTEFVSA
                     DALIRSVNKTQQKLNVADEERPVAIQIYGRDVPTMVEAAQICEAAHPDILDINFGCPVK
                     RVAGKGAGAGMLRNIPLMLDITREVVKAVNIPVTVKTRLGWDADNRIIVDLAEQLQDCG
                     IAALSIHGRTRAQMYTGEADWTLIGEVKNNPRIQIPIIGNGDVTSAEICKQRFEQYGVD
                     AVMIGRGSIGRPWIFREVRHYLDTGETLPAESFSWYLDILKKQVEQSVERLDERRGILH
                     IRRHLAATPLFKGIADFKQTRVAMLRAETVEALFDILDSIPDKFHTGYGFQSDSQVSES
                     IDC"
     CDS             complement(9652..9810)
                     /locus_tag="ctg12_267"
                     /transl_table=11
                     /translation="MKKTHCKYKVYLLNTQEFVITFYCKFATFCFKIDTVCGFTLLLYQ
                     QSIDSDT"
     CDS             complement(10001..10756)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_268"
                     /sec_met_domain="Fer2_3 (E-value: 2e-25, bitscore: 83.0,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 6.1e-11, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.5e-05, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKGPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANAIPISKADADLAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFISAKLQD"
     CDS             complement(10784..12727)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.4; E-value:
                     1.1e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_269"
                     /sec_met_domain="FAD_binding_2 (E-value: 5e-59, bitscore:
                     194.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3.2e-37,
                     bitscore: 121.5, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERFAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDFQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFVEAEKAINARIAKLMNVKGKETVDSIHRKLGHI
                     MWEHVGMARDAEGLKEAIQMLKDLKKEFWSNVFIPGEANSLNVELDKALRLADFIEIGA
                     LMAHDALDRAESCGGHFRTEHQTEEGEAMRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     QFVVPQTRNYKK"
     CDS             complement(12766..13440)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_270"
                     /sec_met_domain="SucD_FumR (E-value: 2e-66, bitscore:
                     217.4, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLILFLVFHLCMNIAAVFSGEAYNVI
                     CGLLGSNWYALLGTLVLAAGVVVHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGVIVILFMVLHFTQFWYNMMFAELAGIHGDIHPQDGAAFINFYFQGNVVNTVLYL
                     IWFVALWFHLTHGFWSAIHTIGWNNTVWLSRWECISKWVATIICGLFAVITVIFYLNGV
                     GA"
     CDS             13700..14653
                     /locus_tag="ctg12_271"
                     /transl_table=11
                     /translation="MKTAIFSIGVFLISLFLGSCQPSETSCSVVDTGKTLDYKIGDKLL
                     FSYNYTTVYPAPGVDSVYKRSGFIHPLKTLGGEVMTNCSPADHYHHFGLWYAWTKTTFE
                     GNEIDFWNLHKKQGTVRFRNFEHVSDNGFVATLDHVVYPDSPAEKVAMNERLEINIGTT
                     SLPGYYIDYHTTIRLASPSPITMEAYRYGGICIRTREDWNDQTAEMLTSEGLSRDEADG
                     SRARWCYYQGKAGNEKACILIVASPSNLNYPEPLRVWDKTVNKPAGDVMWNFSPTKQKA
                     FTLEPGKELSLSYRIYVLDKNINATTAEVLSDFERD"
ORIGIN
        1 tttatatcga ttatattgtt cagatattct atctattcca agtcggcgtc tttcaacatt
       61 ttccgtgctt tctctttttc ttccttactc agggcgagcg tatcaagttt agcatcgctt
      121 ttacgcaatt ccttttcttt ttccctggct tttttaatat gttcctgcat cttctcgcgc
      181 ctcaaacgtt catcttccgg catctgcggt aactgggcga ccaaggcacg cagatcggag
      241 acagccaact tcgtcttctt cccatcggga gccaacatcg tcacttcatc gacattccgg
      301 aaaaaggcat cttcacaaac cgcttccaag aaagggcggt aattataaag atacttttgc
      361 gacttgtctg tcttcatata ggctgtcagg taagtgtatc tactgaaaat cgtcttttgc
      421 aatttttcct cctgctgaaa gagtcccgga tcgacatccc agtattgtgt actgatctta
      481 tacaggaagt gcaactgggt tgggtcttcc ttccatgcgg cataatacag cttttccgct
      541 tcgggccaac ggccgtccct ttccaaggca tcacctcgga aggtcgtcaa catattaact
      601 aggaattttt tcggctgcat attcgtttcc gccagatcga aaagctcata agcccgttta
      661 cggtcgtatg tttttcccag ggaagcgcca tacaacatga ctgtttccac atccgtcgaa
      721 tctatttcat aggccttctc cagcagctcg accccatcaa gtgcatgacc ggacatatag
      781 cgggccgccc ccgcatattt aagattcaaa aaagaagaat cgccatcggc caatagatcg
      841 gtatagactg aatcagcctg cttataatct ttcgtcatat agagagccat ccctttactc
      901 tgccgtatct ggctgttatc cggattatag aacaaggcgg tatcgcacac ctgcaaagct
      961 ccctgtccgt cccccatccg caataacgta tttatcagag aagatgccac acgcacattt
     1021 tccgggttca actccaaagc acgggcatac aaagaaaggg cgatcatcgt attaggaccg
     1081 gtccctcttt taatatggca atcagccagc ccggtcagga tagaaggatt ttcaccttcg
     1141 atggaagcaa gtatatgata gtgttccgtc gctcgaccat aatctcccaa ctgataatag
     1201 agacgcgcca actgatagtt ggcatagaaa ttcatgctgt cggttcccaa tactttacga
     1261 taacattgtt tagcttccgc tatccttccg aaattgatcg cattcctggc aacggcattc
     1321 aatgcatcca cattgttcgt atccatcttc aagcaatgag aaaagcacag ataggcctcc
     1381 ttatagcgca acagtccctc atacgcctgc ccgattgccg acattgtagc ataatcggct
     1441 gaatcggcag gagtaagact atccgcacgt gctacaactt cctgaaattg ttttttattg
     1501 accaattcct gaagattaag actctgcgcc tgtccccaaa gggacagtac gcaaagaaac
     1561 agtaatagag aaaacttaca tttcataatg gtatcgtatt aatgaccgat tctggtcaat
     1621 tactgcaaac ggaaagtaac cggaaccgta tattttacgg ctacagccat attgttttgt
     1681 acgccaggat tccatttcgg catttcccgg atcacccgga cagcctccct gtccagcgaa
     1741 ggatcgattc cacggatcac ttcaatattt ttcaaacttc catccgtgtc gacaacgaaa
     1801 gaacaagaga cacgtccttg tattccattc tcctgagcaa tagccggata ttttatgcgt
     1861 gttgccagat atttcaacaa cgaagcctgt ccacccggaa attccggcat ctgttgcact
     1921 accgtaaaga cacgaccgga cgtatcgact tctttaatct gcctctgcac gatacgagag
     1981 gagttttttt tctttccacc ggaaagccgg aaagttaccg gtaccgtata tttgacatta
     2041 accgctttgc cccgctgttt tcccggcgac cataccggca tggagtttat cacacgcaaa
     2101 gcctcctcat tcagttccgg acttacccca cgaatcactt ctgcctccga gatagccccg
     2161 tcttttccaa caacgaaaga acagctaacc cgtccctcta taccattttt aacggccgat
     2221 tccgggtatc tgacattcgt cgccaggaat ttcagcagag caccctgtcc gccagggaat
     2281 tccggcatta cctccacaac ggtaaacacc tggttacggg cacgtctggc agcctcaatt
     2341 ccttcctccg atagcacata ctcctcacgt ttttcagcag gagaagcatc accgacaaaa
     2401 gggaacggca agatagcctc cggtagtaag acatcggcaa acgtgctttc cgtcagttcg
     2461 tccgtgatcc gggccaatgc atcgacattg ctcaaaatca gcaaggcgcc cacaatcggt
     2521 ataaaaatca ggtatttcgt cctccctatg ctccgggaac gtttcttatt catcatgctg
     2581 atccgatttt tcagatgcag catattaaag ttattagata aagaggtcac cgatctattg
     2641 gtatgtgcca accccaaaag gtgatattgg tagctacgac tgtcatagcc cgattcaagt
     2701 accgtatcat ccgccaaata ttccagatta tgacgtacct ctcttttcaa cagccagaca
     2761 aacggattca cccaacagat gatacaaacc aattcgcaaa taatcacgtc aatcgaatgc
     2821 cactggctga catgcgtaca ctcgtgtacc aaaatctcat cgatctcttt ttcggaatgg
     2881 ctgtcgggat gcagaaatac cagccggaaa aaagaaaaag gaccggccgg tttattcaac
     2941 agatgtacac gtacgttacg gatcaaagtc acttccgacc gccgtgccag taacaagatg
     3001 ctgctcaact gcactaaaaa acggaacgat aaggcaatta caccgctcca ataaagataa
     3061 gaaataccgg gaagtaacaa atcatgccaa tttgtttggg gaacattgcc gggggttatt
     3121 gtcgtttcgg gcaaaatggc tgaatacatt tgtatgactt ccactatcgg cccctgctcc
     3181 cggatccaat cctgaatatt catcagcgga taaagcaatg acaccccgaa aaatgccaac
     3241 aagatggtac ggcgtagttt aaagaaggtg tccttataaa agaacagccg gtagaaggca
     3301 taaaggagta taaaagctac atttaccttc aagaagtagg caaattccgg tgtcatggca
     3361 ttatgtattt aacagtttat tctcgtcctt tttcaatcat atcgataatc tctttcaact
     3421 catcggtcga tatcttctgt tctttagcaa aaaaggagac catttccttg taagagttct
     3481 cgaaatagtt gttcaccaca cttcccataa acgtccgttt atattcctcc tgtgggatca
     3541 gcggcctgta ttcgtaagta tttccgtaac gtttcgcttt cacgtatttc ttacgttcca
     3601 gattcttcac aatagaagcg agtgtcgtat aaggaggctt aggctcttca tacttcgcca
     3661 ggatgtcttt gataaaacac ggctcgatct gccagatcca gcgcattaca tcctcttcct
     3721 gtcttgttaa tctttccatg tttctatatt attttttacg atcgtatcgc aaatctacga
     3781 atacatcgta aatatgcaag aaataatgcg ttaatttgta ttaacaatta ataatccatc
     3841 atctattcgc tgcatgcgcc aaaaaggaat ttatctataa gcagccacac caaaacatcc
     3901 ccctatatta attaatgatt ttatatactc caaggggaca ctttttaagc atgggatttc
     3961 actttttccg acgataaaaa gtatttgaat tagcagtttt tacatggaat ctgtatagtt
     4021 tataaataac caacattttt tgacaaaata gctattagag cttaacatat attatccgta
     4081 aaaggcttga caaacaagct tagctagtgt atttttgcat tgtggttttt tcataatagt
     4141 attagattta aggttaacaa agttggttag gggttgtcga gatgacaatc cttaattttt
     4201 tatatacctg cctctttctt tgcacatctt gttgcctgtc atattttcat gtttttatag
     4261 tgcttttata gtacgccact gataaaaaag tcttactttt aagccgcata attgacaaag
     4321 aatctatata aatacaatat catgaaaatg ctatctttta ttttggtact ccttttaggg
     4381 ggttttatgc ctgccgggaa tcttttggct tcagacaaag aacaaaatcc tcattacatt
     4441 actgtgaaga acagccggga cctacaagcc tatttccggt atgctcccga tcgcccgatt
     4501 gtaatcagtg gacatcgtgg tggaatgcta gacggctatc cggagaactg catcgaatca
     4561 ttcgaaaaga ccttgtccta tatggaatcg tttttcgaga tagatccgcg tttgacaaaa
     4621 gacgggataa tcgtattgat gcacgacgaa accatcgacc ggacaactac cgggaaagga
     4681 aaggtttcag attacactta tgcagaactg caacaattca atctggtgga ccgaaacggc
     4741 aacgtgacag ccttcaaaat tccaacttta aaagaatgcc tggaatggag caaaggcaaa
     4801 acaatcctga atttggatat caaggatgta cctttagaag ttatggccga ttttatagaa
     4861 acagaaaagc ctgttaacgt catgtacacg gtacataacg ccagtcaagc ccgctattat
     4921 ctcgaccgga aactggatgc gatgttttct tgctggtgta agaatcggga agaattcgat
     4981 aattatgaaa aagccggcat cccctggaaa caggtaatgg cttatgtagg cccgaagatg
     5041 aagcctgaac agcaaccact gtatgacgct ctgcaccgta acggagtcat gtgcatgatt
     5101 tccgttgctc cgacacatga tcgcgcgaaa acggaaacag agaaaaccgc cggttaccga
     5161 tcagagatca gcactcgtcc cgacgtgatc gaaacggact atccgtacct gtttcaagga
     5221 ctcgatttaa caaaataacg cagtttaaag gactctttat agccgattaa aatctttttg
     5281 ctatttatgc tcatctgatt aacaagtatt agcgacaaaa tgcttgacaa acgctcttga
     5341 cgagtgtatc tttgcaatgt ggttttttca taatagtatt agatttaagg ttaacaaagt
     5401 tggttagggg ttgtcgtgag acagccttta attgtttata gaggttccgt ttcttctccc
     5461 acatacaaat cgtatacgaa aaagccggtc aggacagctt atagagattt cccggcaacg
     5521 cttttacctt cccgtttatt tccagttcga acaatagcat agagagttga tgtaccggta
     5581 tctccaacac tgaggcaagc tcgttgatat ggatctcatt ccgcgttcgc ataatggcta
     5641 aaaccggatt ttgttccgag gtgaatgttt ccgcctcggc gaaaaacaac tccgtttgaa
     5701 cgggagtagc cccagcttgg atatcccaac aaagagcgga gagcagatcg tccgcagaag
     5761 tgatcaggcc ggctttattt tgtcggatca aattgttgca tcctttggaa tggctgtcac
     5821 cgacacgccc tggaaagcta tagacatccc ggccataaga gaatgcaata tcggcagtta
     5881 ccaaagagcc tcctttttct gccgattcaa ccacgatcgt acaatccgag attccggcga
     5941 caatccggtt cctccggagg aaatttggac ggtctggttc tgtaccgctg ggaaaatcgg
     6001 tcaacagacc gcccgattcc agcatttcga cagccgtatt ccgatggcag gaaggataga
     6061 tacgatccaa gccatgcgcc agcacagcaa cagtcggaag tcggttgtac aaagcgttcc
     6121 ggtgggcaca gatatcgatg ccgtaagcca atccactcac gaccaacaag tccgggatca
     6181 cttttgccaa gtcttttata agggattcgg taagctcccg accatattcg gtcgcgttgc
     6241 gagtacccac aatactgatg atacgggttg catcaaggtt agtatttccc ttaaaataga
     6301 aaagtatagg ggcatccgga cattctctca agcgcaccgg ataatctgta tcagtcagat
     6361 aataacagga aatattgttt ttctcgataa aagccaactc tttttccgcc cgttgcaaga
     6421 tttccgggcg tttgatttcg gcagcaatat tgctgccgat accagggatc cttcctaaca
     6481 actgttgctt ttcagtaaac acagcctctg cttctcccaa agcctgcagg agatgacgcg
     6541 ccaggatatc tcccacgccg tttatcatag taaggccgat ttggtaaatc cgtttgtcag
     6601 tcatgtatgt tctattcttt ttagcatttc gtcgaaatat tcaccgcgtg tcaactttcc
     6661 gttctcaacg ataaccgact cgacgattcc tttcgtcgcc aatgcattgt cagaagccct
     6721 atatatatcc tgctcgaata cgagcttgac tcctttttta tagacattga ggcaagagat
     6781 atagctgtcg ccgctcttga gcgaggtctt atactggatt tctacccgcg atacaaatcc
     6841 gtcaacccct ttttcgtgca tctttccgaa gttctcacca agcgactcca agaattcatg
     6901 ccgagtatgt tccatataat gctgataatt ggagttgttg accactcctt gcaggtcgca
     6961 ttcgtagtca cggaccttgt ctgtcagttt aaaaatatac tctttcatta ttcaaatacc
     7021 ttttcaagtt gaaccttttc cattttatac aatcggtcag acggccgaat cttctcgttc
     7081 accttgagag agaaccgttc acctttaacg gtctcgtcca ccggcttcaa gtccacacgg
     7141 atttcttcta tcgtctgcat aaccgcaccc gttgtcggtc cggtaatcag gatctcatca
     7201 cccactttca ggttaccgga ttccatttcg aactccgcca cgccgatctt gtcgaaatat
     7261 ttgattcctt tggcaacata cactttcttc ttagtcgcgc cggagccata tttgctactc
     7321 cactcaccca accgttgccc caaataatag ccgtcccaga atcctcggtt gaacacactg
     7381 cgcaggcgtt cgtcccaagc ggcaactttc ttttcatcga acgtgccatt gcaataggca
     7441 cgcacagctt ccttatagca ttcggtcacc aggcggacat attcaggacc gcgggcacgt
     7501 ccttcgatct tgaatacccg tacacctgca tccatcatct tattcatgaa atgaattgtc
     7561 ttaaggtctt taggcgacat aatatactgg ttttcgatat ccagttcgat attgctgtct
     7621 ttatctttta ccgaataagc acgccgacaa atctgcatgc aagctccccg gttggcggaa
     7681 gcgttcattt cgtgcaggct caggtaacat ttaccggaaa cggccataca gagagctccg
     7741 tgggcaaaca tttcgatacg gatcagttct cctttcggtc ccgtaatctg ctggtcgacg
     7801 atctgccgat agatttcatg cacctgtttc aaattcagct cacgcgccaa gacgacaaca
     7861 tcggcaaaac gggcatagaa tttcagtgct tccgcattgg aaatgttgag ctgtgtggaa
     7921 agatgcacct cctgtccgat gctgttggca tagttcatag ctgccacatc ggccgcaatg
     7981 atcgctgaaa cttccgcctc cttcgccgca tcgataatct cgcgcatcag aggcaggtct
     8041 tccccataaa taaccgtatt gacggtcaaa tagctcttaa taccgtgctc acgacaaagc
     8101 gcaacgatct tgcgcaaatc gtctgtcgta aagttattgg aagagcgcga acgcatattc
     8161 aatccttcga taccgaaata gatagaatcg gctccccctt ggatagccgc catcagtgat
     8221 tcgtacgaac cgacaggcgc cattatttca aaatctttct cgttcaagtt cttatacatt
     8281 tactggttcg ttcgcaaagg taggaataat atccgagaag aattgcatgg gtatccgttt
     8341 ctcagagcat caaaatcgtg atcaaatacc attttctata aagatttgca aaacaaccat
     8401 catactggca ttgttgtcct ttagaatctg ttattcaata ccttaagaca tgatagtttc
     8461 tatttttaac tatcatacta ctatcatgca actatcatga tttcagctta tcattttatc
     8521 tatatcattg acagtatgac atttgtactt tttattgatc aattactaca ttttttagta
     8581 gatatccttt tatccctgtt tttagcagga aatcagtacc tttgtccccg tcattgataa
     8641 tataaatatg aaaataggta caatagattt aggcgaacgc cccatcttct tagctccgat
     8701 ggaagacgtt acagatattt ctttccggtt gatgtgcaaa cgttttggtg ccgatatggt
     8761 ttataccgaa tttgtttcag cagacgccct gatccgcagt gtaaataaaa cacagcaaaa
     8821 gctgaatgtg gcggatgaag aacgtccggt cgccatacaa atatatggcc gtgatgttcc
     8881 gacaatggtc gaagccgcgc aaatttgcga agccgctcat ccggacattc tcgatatcaa
     8941 tttcggttgc cctgtcaaac gagtggcagg caaaggagca ggcgccggca tgctgcgcaa
     9001 tattccactg atgctggaca tcacccgtga agtcgtcaaa gcggtgaaca tccctgtcac
     9061 cgtaaaaacc cgcttgggct gggatgccga caaccggatc atcgtagact tggccgaaca
     9121 actacaggat tgcggtatcg cagccctttc catccacgga cgtacccggg cacagatgta
     9181 cacaggagag gcagactgga cactgatcgg tgaagtaaaa aacaatcccc gcatacaaat
     9241 tcccatcatc ggcaatggcg atgtgacttc cgccgaaatc tgcaaacaac gtttcgaaca
     9301 atatggcgtg gatgccgtta tgattggccg gggtagcata ggccgcccct ggattttcag
     9361 agaagtgagg cattatctgg atacaggcga gacattgcct gccgaatctt tttcatggta
     9421 tttggacata ctgaaaaagc aggtggaaca aagcgtggaa cgtttggatg agcgccgggg
     9481 aattctccac attcgccgcc atttggctgc aactccgctg tttaaaggta ttgcagactt
     9541 caagcagaca cgcgtcgcca tgctacgtgc ggaaacagtg gaagcattat tcgacattct
     9601 ggattccatc cccgacaaat ttcatacagg atacggattt caaagcgact ctcaagtgtc
     9661 agaatcgatc gattgttgat ataataacag tgtgaatccg cacacagtgt caattttaaa
     9721 acaaaaagta gcaaatttgc aataaaatgt aattacaaac tcttgcgtat tcagtaaata
     9781 tactttatat ttgcagtgag tttttttcat agtattttag atctaaggtt aacaaagtct
     9841 ttgcagagag ggaatcgaga gactgtttca ctggaaagca acaaaaaagc cgcatccact
     9901 tttattatag ggagtgcggc ttttttgtgg gtttgaacga acataaagaa agcccgttgc
     9961 cattgacgac gggcttttcc atatacatat atataatgta ttagtcttgt aacttagcag
    10021 agatgaactc gcggttcaag cgagcgatgt tgctaacgga gatgttcttc ggacattcca
    10081 tttcgcaagc gcgagtgttc gtacagttac caaagcccag ttcatccatc ttagcaacca
    10141 ttgcttttgc acgacgagca gcttccacct taccctgagg caaaagagcc agctggctaa
    10201 cctttgcaga gacgaacagc atagctgaac cgttcttaca agcagcagca caagcaccgc
    10261 agccgataca agcagcagca tccatagcca aatccgcatc agccttagaa ataggaattg
    10321 cattagcatc aggaacccca cctgtgttta cagaaacgaa accacctgcc tggataatct
    10381 tatcataagc ataacggtct accatcaagt cgcggattac cgggaaaccg gcagaacgcc
    10441 acggctcgat cgtaatcgtc tcaccatcat tgaaacggcg catatagagc tgacaggttg
    10501 ttgcacctgt tgccggtccg tgcggatgtc cgtttacata caatgaacac ataccgcaga
    10561 taccttcacg gcagtcgtgg tcgaatacga taggttcttt accttcgcta accaaacgtt
    10621 cattcaaaat gtctaacatt tccaagaaag aaacactctg attgattttg tcgatttggt
    10681 aagtctcaaa ctgtccttta tctttcggac ctttctgacg ccaaacttta agtgttacct
    10741 ttatatcttt atccatgatt ctaatttttg tgattgatga ttattacttc ttgtagttac
    10801 gtgtttgagg aacaacgaac tgatagttca aatcttcctt cagcataacc gggtctttgt
    10861 cttcaccctg gtattcccaa caagagacgt acatgaactt atcgtcatga cgcatagctt
    10921 cgccttcttc ggtctgatgt tccgtacgga agtggccacc acaagattct gcgcggtcta
    10981 acgcatcgtg tgccatcaat gcaccgattt cgataaagtc agccaaacgc aatgccttgt
    11041 ccaattccac gttcaagctg ttcgcttcac ccggaatgaa tacattgctc cagaattcct
    11101 tcttcaggtc tttcaacatt tggatagctt ctttcaaacc ttccgcgtcg cgtgccatac
    11161 cgacgtgttc ccacatgata tgtcccagct tacggtggat agaatcgact gtttctttac
    11221 ccttcacgtt catcaacttc gcgatacggg cgttaatagc cttttctgct tccacaaatt
    11281 caggcaggtc agtgctgaag cgcggaacct ggatctggtc agacagatag ttctggatcg
    11341 tgtaaggcaa tacaaagtaa ccatcagcca atccctgcat caaagcagaa gcacccagac
    11401 ggttagcgcc gtggtcagag aagttggctt caccgattgc gaacagcccc ggaatagaag
    11461 tcatcaattc atagtctacc cacaaaccac ccattgagta gtgcaatgca ggataaatca
    11521 tcatcggagt ttcgtacgga tcatcgttcg tgatctcttc gtacatatcg aacaggttac
    11581 catatttctg tttaaccact tccttaccca gacggttgat agcatcggag aaatccagga
    11641 atacagccaa gcccgtgcta tttacaccga aaccggcatc acaacgttct ttagcggcac
    11701 gtgaagccac atcacgagga accaagttac cgaatgccgg ataacgacgt tccagatagt
    11761 agtcgcgatc tgcttcagga atatccttac ctttttttgt tccggcctgc aatgccttcg
    11821 catcttccag cttcttcgga acccagatac ggccgtcgtt acgcagtgat tctgacatca
    11881 aagtcagctt agactggaag tcacctttca ccggcacaca agtcgggtgg atctgcacca
    11941 tacaaggatt agcaaagtaa gcccctttct tgtagcactg ccatgcagca gaaccgttag
    12001 acgccatcgc gttagtagac aagaagaatg tatttacata accacctgtc gcaacaacga
    12061 ctgcgtgagc ggcaaaacgt tcgatcttac cggtaatcaa attacgggca ataataccgc
    12121 gagcacgtcc gtcaaccttc acaacatcca gcatttcatg gcgtgtgtac atcttcacct
    12181 ttcccaaacc aatctgacga ctcaatgcag agtaagcacc caacagcagc tgctgtccgg
    12241 tctgaccacg ggcatagaac gtacgggata cctgagcacc cccgaatgaa cggttatcca
    12301 acagaccacc atattcgcga gcgaatggta caccctgtgc tacgcactgg tcgatgatag
    12361 agtttgacac ttcagccaga cgatagacgt ttgcttcgcg ggcacggtag tcaccacctt
    12421 tgattgtatc gtagaacaga cgataaaccg agtcaccatc attctgataa ttctttgccg
    12481 cattgatacc gccctgtgca gcgatagagt gtgcacgacg gggagagtcc tgaatacaga
    12541 aattcaatac attgaatccc atttcagcca gagaggcagc agcagaagca cccgccagac
    12601 cagtacctac tacaattatg tccaaacgac gtttgtttgc gggattcacc aatttctggt
    12661 gatttttata atttgtccac ttctcagcca acgggccttg aggaatttta gaatctattt
    12721 gagtcataat gttttatttt caaattgaaa aaataatatc cgaaattaag cacctacacc
    12781 gttcaggtag aagataactg tgataacagc gaataagcca caaataatag tggcaaccca
    12841 tttagagata cattcccaac ggcttaacca aacggtattg ttccagccaa ttgtgtgaat
    12901 cgcagaccag aaaccgtgag tcaggtgaaa ccacagagca acgaaccaga tcagatacaa
    12961 caccgtattc acaacattgc cctggaagta gaaattgata aacgctgcac catcctgcgg
    13021 atgaatgtca ccatgaatac ctgccagttc ggcaaacatc atgttgtacc agaactgagt
    13081 aaagtgcaga accatgaaca ggataacgat cacacccaaa acaaacatgt tctgagaagc
    13141 ccattcaaca cctttcggac gagcgttgat ggcataacgg tcgttaccgc gagccttacg
    13201 attctgcaga gtcaagataa tagcatacac gaagtgcacg actacacctg cagccaacac
    13261 caatgtaccg agcaaagcat accagttaga acccagcaaa ccgcaaatca cgttatacgc
    13321 ttcaccagaa aatactgccg caatgttcat acataagtgg aacaccaaga acagaatgag
    13381 aaaaagacct gatatactca ttatcagctt cttcccgata gaagaattaa gtaaccacat
    13441 aagataataa tttaagttat ttaattgtat ttagaaattt cctccaatct atggttatta
    13501 tcgtgcaaag gtatgctaaa tccccatatc acgcaaacga ttaaagaaat atttcatcaa
    13561 ttagaacgct gcttgctggc tggttttatt tgcatcagat atcacaaacg gattgtgcga
    13621 aacgaaaaaa tttcgttttt ttgtagccga tacaggcaag gtcttgccgg ataactgatt
    13681 attatttaat tgtcatatta tgaaaactgc tattttttct attggtgttt ttttgatttc
    13741 tctgttctta ggctcttgtc agccttccga aacatcctgt tccgtcgtcg acacggggaa
    13801 aaccttagac tataagatag gagataaact gttgttctct tacaactata ccacggttta
    13861 cccagcccct ggcgttgact cggtctataa acgcagcggt ttcatccatc ctttgaagac
    13921 attgggaggc gaagtgatga ccaattgttc tcccgccgac cattaccatc atttcggttt
    13981 gtggtatgcc tggacgaaaa ccacgttcga aggaaacgag atcgatttct ggaatctcca
    14041 caaaaaacaa ggaacagttc gcttccgcaa cttcgaacac gtatccgaca acggttttgt
    14101 tgcgacactg gaccatgtgg tctaccccga ttctcccgca gaaaaagtag caatgaacga
    14161 acgcctggag atcaacatcg ggacaacatc cttaccaggt tattacatcg actatcatac
    14221 cactatccgc ctcgccagcc ccagcccgat caccatggaa gcttaccgtt atggcggcat
    14281 atgcatccgt acgcgcgaag actggaacga tcagacagcc gaaatgctca cctcggaagg
    14341 cctttcccgc gacgaagctg acggttcgag agcccgttgg tgctactatc aagggaaagc
    14401 cggaaacgaa aaggcctgta tcctaatcgt tgcctcccct tccaacctga actatcctga
    14461 gcctttacgc gtatgggaca aaactgtcaa caagcctgcc ggtgacgtca tgtggaattt
    14521 ctcaccgacc aagcagaagg cattcacctt ggaacccggt aaagaactga gcctgtctta
    14581 ccgcatttat gtattggaca agaacatcaa cgctactacg gcagaagtgc tgtccgattt
    14641 cgaacgtgat tgaatttcta ctaaaacaaa ctgacaattt gcagggcaag gtaaacaaga
    14701 gaaggaaaaa gggcttgttc tcctatatca tcaaagacaa ggctctttta tgtaaataca
    14761 gctacaaatc aatgagaaac acgtaataaa acttacccaa cacccccatg tatccgcccc
    14821 cgacacccgg atctataaga gcgtaagatc cgggtgtcgg gggcggatac atgggggtgt
    14881 tggtgaaatt gtctccctac ttttacctta aaatgcttgg agtttattca tttaaaacag
    14941 atagatgagc gattgtctcg tcctgaaata ggttgacttc ataaaagtca acaaagatga
    15001 aaaaagagaa g
//
