LOCUS       c00230_gnlPro..        15251 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LAIOAOAE_266.
ACCESSION   c00230_gnlPro..
VERSION     c00230_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 20:25:01
            Original ID  :: gnl|Prokka|LAIOAOAE_266
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15251
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15251
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2275:5251]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2276..5251
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15251
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15251
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(111..1391)
                     /locus_tag="ctg230_1"
                     /transl_table=11
                     /translation="MKIEKITGREILDSRGNPTVEVDILLESGVMGRASVPSGASTGEN
                     EALELRDGDKKRYGGKGVLKAVENINTIIAPALKGMSALDQIGIDHAMLALDGTKTKSK
                     LGANAILGVSLAVAKAAANYLDIPLYRYIGGTNTYVMPVPMMNIINGGSHSDAPIAFQE
                     FMIRPVGAASFKEGLRMGAEVFHALKKVLHDRGLSTAVGDEGGFAPNLEGTEDALNSII
                     AAIKAAGYEPGKDVMIGMDCASSEFYKDGIYDYTKFEGEKGVKRTSDEQVDYLEKLINE
                     YPIDSIEDGMSENDWAGWKKLTDRIGNHCQLVGDDLFVTNVEFLSRGIKEGCGNSILIK
                     VNQIGSLTETLNAIEMAHRHGYTTVTSHRSGETEDATIADIAVATNSGQIKTGSLSRSD
                     RMAKYNQLLRIEEELGDRAVYGYKRIN"
     CDS             complement(1499..2158)
                     /locus_tag="ctg230_2"
                     /transl_table=11
                     /translation="VFVLLYATNIYFCKEIKNDIDQKMMNSMKTPQEIAEMISKRFYPL
                     PDADLDSLASIIESSKAAKGELLLDNGQISKYLYYVESGLLRQFYYKNKRDITEHFSCE
                     GNIVICIASTFQREPTRLLIEALEPTVYHRISFSEFSDLLKTSLAINRLYQKILEWALM
                     LSQEKADSWRFESARKRYLRFQQEYPEAAKRASVNHIASYLLMTPESLSRVRAGVL"
     CDS             complement(2276..3010)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 67.6;
                     E-value: 4.7e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg230_3"
                     /sec_met_domain="Radical_SAM (E-value: 2.6e-33, bitscore:
                     106.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VIKGKIHSLESFGTVDGPGIRFVVFMQGCPLRCLYCHNPDTWNPK
                     GKVKYQMTPGELLTEVLRYKSFIARGGVTVTGGEPLLQPEFLKEFFRLCQEQGLHTALD
                     TSGFVCTSKAWEVLDYADLVLLDIKTLNPDLHPLLAGVKQDNTLLFLDELERRGIDTWI
                     RHVIVPGYTDNDEWLEALARYVSSYKVVRKVELLPYHTMGTYKYEQLGLDYPLKGVEPL
                     SKERLDNAKAIFSRYKPENNKA"
     CDS             complement(3011..5251)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg230_4"
                     /sec_met_domain="Gly_radical (E-value: 1.1e-45, bitscore:
                     145.1, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 1.1e-281, bitscore:
                     925.8, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFENEYWDHFKGETWKREINVRDFIQSNYTPYEGDDSFLVASSE
                     KTRKVWNKLTEMFKVEREKGVYDAETKLPQGIDVYGPGYIDKENEVIVGLQTDAPLKRG
                     IFPKGGIRMVENSLEAYGYHLDPMTKEIFTKYRKTHNEGVFSAYTEEMVAARRSAIITG
                     LPDAYGRGRIIGDYRRVALYGTAILIEEKKRFLNRLDIQEITEEIIQSREEISEQIKAL
                     KAFERMCASYGFDVTRPAQNAREAVQFVYLAYLAAVKDQDGAAMSIGRTSTFLDIYIEK
                     DIREGKMTEEEAQELVDQLIIKLRIVRFLRTPEYNDLFSGDPVWVTESLGGQGVDGRSL
                     VTRTSYRYLHTLYNLGPAPEPNLTVLWFKNAPENWKRFCAKVSIDTSAIQYENDDLMRP
                     DYGDDYGIACCVSPMKIGKQMQFFGARANLAKCLLYAINGGRDERSGVQVAPMFEPVRS
                     EYLEYDEVMAKYEQMMRWLAKVYVNALKIIHYMHDKYAYEAFEMSLHDGDVERIRATGI
                     AGLSIVADSLAAIRDTKVRVIRDERGLAVDFEREGEYVPFGNNDDRTDSIAVEITEKFM
                     EYLRQHETYRHAKPTQSILTITSNVVYGKKTGTTPDGRIGGTPFAPGANPMNGRDTKGA
                     IAALASVAKLPFQHAHDGISYTFAVSPATLGKEREMQINNLVSLLDGYFTPDGGQHLNV
                     NVFDKDLLIDAMEHPEKYPQLTIRVSGYAVNFVKLTREQQLDVISRTINHSL"
     CDS             complement(5264..5416)
                     /locus_tag="ctg230_5"
                     /transl_table=11
                     /translation="METSCKASHYYPVSSCIFLIPIYRDFRGVSQMLQEHEDKSFTFVP
                     VKMWY"
     CDS             5565..9512
                     /locus_tag="ctg230_6"
                     /transl_table=11
                     /translation="MINLSNNAIICMHQDPDGYLWIGTYDGLNLYNGKDTYVYRFELNN
                     KNSLCSNIIHKISDAEPGFLWISTSLGINKFSLKKRKVTESYPGYMESDLVATDSSGIT
                     LAICKENRISCYTPFSDGFRDLPREGIGPQTVRTLFAGTDGYFYLLLTSGILKKLTPDF
                     SNTTFNLLSEERQFHNKPILSAFHENNHIFIVDTDNKLYRQQVDGSGKEFLFDLSGMTN
                     KYGNIIKICTFQSNVYIVFRNGNILDLSQPENTIDTGIGIFCLMNDKRQEILWVGTDGQ
                     GIRMFYDKPDLFGSILLKDLPINIQNPIRSLYTDNDRSLWFGTKGDGIVRIQAYDTYPN
                     KKAIPQSAITHFTTADGLSSNRVYSFQRSEFHPCIWIGTEGPGLCYYSYKENRIKTIPQ
                     QEDTPPIRYIHSICEVNDSTLWLATTGNGLLKVTLRMDKVTPTISKIQTFPLKNGENTC
                     KEIQSMIYDNDSTLFLGSRGGYGVISFNIFNQKYEFLQTNNLRNPAIGDVLSVCQTEDS
                     TFYAGASSGLTRIKFKRGKIHLRQFDKSNGIANDMIHGIHEGNDSCIWLSTNKGLTKYN
                     PRNNFFHNYHQPYFSVTEFSDDAYWKCPYSERLFFGGINGLVWVNKQTEPEHTYQPELS
                     FFELQMDKQILPLYKDISRNGVTVPADVQSLTIAFVAPDYINGENYEYSYQLVNYNSSW
                     EKLQKTNKVTFMNLPYGEYLLKVRYRNDVIDSSAKEYTLPIKVLPPIYLSSLAIFTYLF
                     IGTVLIIIAIYRIHYQILKKQKQIADKIKEEQKEKLYEESKLNFFTHITHELCTPLTLI
                     NGVENYIQAYAATSKDKTLEKYTSVLRENVEELNGLIQEILDFRKAEDAGFSHTHIRRV
                     SVSSLLRTQFEWFYPLSEQHQIQFKIDAPKELYWNTDSVYFKKILANLISNAFKYTEDG
                     GTVRISLHEEENFLVLKVYNTGKGIEEADMQNIFDRYRILGTMDNDDNRQNTARNGLGL
                     FICHSLVQSLGGKIDIESEVGQYAEFTVTLPFGIVEESSDDTIDEDIPVSLPSPNTDIQ
                     KPQISHTAQKETEDKPMILVIDDHKDIVWLITETLSSEYQVQEAYNAEEALEFLKQYTP
                     SLIITDIMMPNIDGLELISLIKENRYTRHIPLIIVSAKISDQEQAAGLNIGADAYLTKP
                     FSPTVLLSVVNRLMTNQRELKEYFYSPESAYQYTEGQLLHQEDKEFLDAVTAIIKENVS
                     KEGLGPELVADALNINTRILYRRFKKISTMTPSDFIKDYRLNYAAQLLVNTNMSVQEII
                     YNVGISNKSYFYREFARKYNMTPKEYRTKEA"
     CDS             complement(9541..9687)
                     /locus_tag="ctg230_7"
                     /transl_table=11
                     /translation="VLPEGRIHTSGLLCYSTAILIGLNELKSALKYRRSVMKCIWQIMI
                     LFW"
     CDS             9715..12777
                     /locus_tag="ctg230_8"
                     /transl_table=11
                     /translation="MKKKSEGKTRKCLTLLGGRTSLLLCLSLMFQSSYAAEDSTVPEMG
                     NMEIHQIAQQSSTIKGVVKDQKGEPLIGVSIVVKGTTNGTASDFDGNFTLDVPDNSTLV
                     FSFIGFKSQEVRYTGQKTLNIVLAEDSETLDEVVVVGYGSQKKGEITSSVTSVKASDFN
                     KAPVVNPMQLVEGRVAGLTVSRGSTDPNGEVKVQMRGASSLKGSNEPLVIIDGMPGNMT
                     SLNAIAPEDIEAIDVLKDGSAAAIYGTRGNNGVIIVSTRRPQAGTTQVDYSGYIMHEAV
                     YKRPEILNGDEFVAYGKETNNANIRDFGGRDNHYDALLNKSNFTHVHNLTATGGNGKTN
                     YRASLNYKKNDGMIRNTSRETINGSIAVNHRAFDDKLQLSFNLANSFVKVDAVSDDVDK
                     VGDIPNYGILYQAIRINPTMPIYKEDGSFWETYSGYEDFNPVARIYQRTKKKEFKNLLA
                     NFKAQYEIIPGLTAAAFFAMEKNDALTNDYSMREEYSQYKDGTNGRAKKEYYQNTNRTT
                     EWTANYNTSINGVHNITGLLGYSYQDFEYEQFSAENKNFLTDVFGTNNLEAGGYLKDGK
                     AEMKSKKETSKLIAFFARANYNYDGKYMASASIRREGSTKFGANNKWAWFPSVSAGWMI
                     SREDFMESQEVFDVLKFRAGFGITGSLPTDPYMSLATYGTGAGAWYAYTGSWLTATYGP
                     NINPNPDLKWEKNESLNIGFDFGLLGGRLNGTIDWYSRTTRDLISSYNAQQPSLIYNTI
                     TTNVGTMRNRGIELALNAEVVKTKDFSYTANFTFSYENNKLTSLSNDVYKSSYEDQYDL
                     PSPGNPGKAYRLQEGQPIASFFGYVCDGINPDGTWNLRDIDGKEGLSDADRTFIGNGLP
                     KFKAGLQNTFTYKNFDFSFFLRGMFDYDVLNEGAIYFGTTVNIDQSGTNVYKDALKNKV
                     TEQPLFSSYYLEKGNFLKIDNVTLGYTFNFKNNKYVRNLRIYGNVTNLATITGYSGLTP
                     DVNVTGLQAGIEKRGSYPTTRTFTFGVNFGF"
     CDS             13224..14402
                     /locus_tag="ctg230_9"
                     /transl_table=11
                     /translation="MSKAQAQAEMRVYRAYCYWYVMDMFGTAPICEKIGEINPSSKSRT
                     ELFAWIEKELNESIPSLSESKTETYGRVSKWGAYALLARLYLNAEIYTGQARWDDCIAA
                     CDELAKGGFALDKKWNDTFRADNDKRSTEIIWSIVYDEVYAKGMGWYQRWLHYAHQTGW
                     DLQSGPWNGLVTQPTFYDSFADNDLRKIEGFLIGKQYPRKVDENGNYYYDTTAEPLKGS
                     EEYNGQDLVFVNYIKSMTEGEENSGARSIKYEIQPGTTGDMNNDWVMFRYSEVIYNKAE
                     ALMRKNGGKATQEVVDMINSVRQRSFKAEDWEKAKYTTATLTMDEFLAEKGREFAFEGI
                     RRTDLVRFNKFVTTSWWDKTASNEPKRNIFPIPQRQLDANANLSPNEANSLF"
     CDS             complement(14632..14886)
                     /locus_tag="ctg230_10"
                     /transl_table=11
                     /translation="VAGTAEVGVAETYDATVFMLITRTILVGARLVFTIYVVWYGIRIR
                     TELYESEGYASTRERMSHSIRPDDRVYKINYTGLCDRYC"
ORIGIN
        1 agataatact ttatcaatca ataaaaaggg cctatcctca cggataagcc cttcaatatc
       61 ttgggttttg gattactaca taattagcga ttataattta ctttatatac ttaattgatt
      121 cttttgtatc cgtatacggc acggtctccc aattcctcct cgatacgaag cagctggtta
      181 tatttagcca tacggtccga acgacttaat gatcccgtct tgatctgtcc gctattggta
      241 gcgacagcga tatcggcgat cgtagcgtct tccgtctcac cggaacggtg tgaagtaacg
      301 gtcgtgtatc catgacggtg agccatctcg atagcgttca gtgtctccgt caaggaaccg
      361 atctgattta ccttgatcaa gattgagtta ccgcaacctt ctttaatacc ccttgaaagg
      421 aactctacat ttgtcacgaa caaatcatct ccgactaatt ggcaatggtt accaatacga
      481 tctgtcagtt tcttccaacc agcccaatca ttctcactca taccatcctc aatggaatcg
      541 atcgggtatt cgttgatcag cttttccaga taatccactt gttcgtcgga agtacgtttc
      601 actccttttt ctccttcaaa cttcgtgtaa tcgtagattc catccttata aaactcagaa
      661 gaagcgcaat ccataccgat catcacatcc ttgcccggtt cataaccagc cgccttgata
      721 gcggcgataa ttgagttcaa ggcatcttcc gtaccttcca aattcggggc gaaaccaccc
      781 tcatcaccaa cagcggtact taacccacga tcgtgcaata cctttttcaa cgcatggaat
      841 acctcagcgc ccatacgtaa gccttccttg aaagaagcgg cacctaccgg acgaatcata
      901 aactcttgga aagcgatcgg agcgtcgcta tgcgaaccgc cattgattat attcatcatc
      961 ggaacaggca tcacgtaggt attcgttcca ccaatatatc tatataaagg aatatccaaa
     1021 taatttgcgg cagctttcgc tacagctaaa gaaacgccaa ggatagcgtt cgcacctagt
     1081 ttcgatttag ttttcgtacc gtccaaagcc aacatcgcat gatcgatacc tatctgatcc
     1141 aaggcagaca tccccttcaa tgccggagcg ataatcgtat tgatattctc aaccgctttc
     1201 aatacgcctt taccaccata acgcttctta tcgccatcac gcaactccaa agcctcgttc
     1261 tcgccggtgg acgcaccgga aggcacagac gcacggccca taacgccgga ctctagtaaa
     1321 atatcaacct ctactgtcgg gttacctctt gaatctagga tctcacgtcc tgtaatcttt
     1381 tctattttca ttgcttctac gttttttaaa ctgacgcaaa tatagatgga ttacttgaac
     1441 cgtgaaatca ccacaaattg ctattttcac ctcaataata cctgaatgta ggtagagact
     1501 acaacactcc cgcccgcacc cggctcaaag attcgggtgt catcaataaa tacgaggcga
     1561 tatgattgac agaagcacgt ttcgctgctt ccggatattc ctgttgaaaa cgcagataac
     1621 gttttcttgc cgactcaaaa cgccaagagt ccgctttctc ttgcgaaagc atcaaagccc
     1681 actccagtat tttctggtac aatctattaa tagctaaaga tgttttcaat aaatcgctaa
     1741 attccgaaaa agagatccgg tgataaaccg tcggttccaa tgcctcgatt aataaacgcg
     1801 tcggttctct ttggaatgtg ctggctatac aaataacgat atttccctca caggagaaat
     1861 gctcggtaat atcacgttta ttcttatagt aaaactggcg taataatccc gattccacat
     1921 aatataaata tttagatatt tgtccgttat ccaacaataa ttctcctttc gcagccttac
     1981 ttgattctat gatcgaggcc agagaatcca aatccgcatc gggtaatgga taaaaacgtt
     2041 tggatatcat ttcggctatt tcttgtggtg tcttcatact attcatcatt ttctgatcta
     2101 tatcattttt tatctcctta caaaaataga tatttgttgc atataacaaa acaaacacat
     2161 attaaatagt caaggttagt ctaggcaaaa aattattact atcgtttaaa agctaatcgg
     2221 attagattgt tttccctgat tagctgttgc ataatcgcaa ggcttgatcg agagatcagg
     2281 ccttgttatt ttctggtttg tagcgagaga atatcgcttt cgcattatct aaacgttctt
     2341 ttgataaggg ttccaccccc tttaacggat aatcgagacc taattgctca tatttatagg
     2401 ttcccatcgt atgataaggc aataattcca ctttgcgaac cactttatat gaactgacat
     2461 accgagctaa cgcctccagc cactcgtcat tatccgtata tccggggaca ataacatggc
     2521 gaatccaagt atctatgcca cgtctctcca attcatccaa gaacagaagc gtattatcct
     2581 gcttgacacc cgccagtaac ggatgtaaat ccgggtttaa ggttttgatg tccaataaca
     2641 ctaagtccgc ataatccaag acttcccaag cttttgaggt acatacgaaa ccagatgtgt
     2701 ccaaagctgt gtgaagacct tgctcttggc acaaacggaa aaactctttc agaaactcag
     2761 gttgcaataa aggttcccca ccggtaacag tcaccccccc acgggcgata aaactcttat
     2821 accgtaaaac ttccgtcaat agctcgccgg gagtcatctg atatttcacc ttccctttcg
     2881 ggttccaagt atccgggtta tggcaataca ggcaacgcaa cgggcagccc tgcataaaaa
     2941 cgacaaagcg aattccggga ccatctacgg tcccgaaact ctctaatgaa tgtatcttac
     3001 cttttatcac ttacagtgaa tggttaatgg ttcttgaaat aacatccaac tgttgttcac
     3061 gagtcagttt cacgaagttt accgcatatc cggatacacg gatcgtaagt tgcggatatt
     3121 tctcgggatg ttccatagcg tcgatcaaca aatccttatc aaatacgtta acattcagat
     3181 gctgacctcc atccggagta aaatagccat ccaataagct aaccagatta ttgatctgca
     3241 tttcacgctc ctttcccaac gtagccggag aaacagcgaa agtataagag atgccgtcgt
     3301 gcgcatgctg gaatggaagc ttcgctaccg aagctagcgc agcgatagca cctttcgtat
     3361 cacgaccgtt catagggttc gcgcccggag cgaaaggagt tccaccgata cggccatccg
     3421 gtgtcgtacc agtcttctta ccatatacca cattagaggt gatcgtaagg atggactgcg
     3481 taggtttcgc atggcgatag gtctcgtgct gacgcaaata ttccatgaac ttctcggtga
     3541 tctctacagc gatactatcc gtacgatcat cgttattacc gaaaggaaca tattcgccct
     3601 cacgttcgaa atcaaccgcc aagccacgct cgtcacggat cacacgtact ttcgtatcac
     3661 ggatagcggc caacgaatcg gcaacgatag aaagaccggc gatacctgtc gcacggatac
     3721 gctctacatc cccatcgtga agcgacatct cgaatgcctc atacgcatat ttatcatgca
     3781 tataatggat tatcttcaag gcgttcacat ataccttcgc caaccagcgc atcatttgtt
     3841 catacttagc catcacctca tcatactcca gatactcact gcgaaccggt tcgaacatcg
     3901 gggctacctg tacgccgcta cgctcatccc gtcctccatt gatcgcatac aataaacact
     3961 tcgctaaatt cgcacgagcg ccgaagaact gcatctgctt tccgatcttc atgggggaaa
     4021 cgcaacaagc gataccataa tcatccccat aatccggacg catcaaatcg tcattctcat
     4081 attggatagc cgacgtatcg atagagacct tggcacagaa acgtttccag ttctcgggag
     4141 cgttcttgaa ccacagcacc gtcaagttgg gttccggtgc cggacctaaa ttatacaatg
     4201 tatggagata acgataggaa gttctcgtta ccaaagaacg tccgtccact ccttgaccgc
     4261 ccaacgactc tgttacccaa accggatcac cggagaacaa atcattgtat tccggtgtac
     4321 gtaagaaacg aacgatacgc aacttgatga tcagctggtc tactaactct tgcgcctcct
     4381 cttccgtcat cttaccctca cggatgtctt tctcgatgta aatatccaag aatgtagagg
     4441 tacgtccgat agacattgcc gcaccatcct gatcttttac cgctgccaga taagccaaat
     4501 acacaaactg aaccgcctca cgagcatttt gcgccgggcg ggtcacgtcg aagccataac
     4561 tagcgcacat tctctcgaac gctttcaacg ccttgatttg ctcagaaatc tcctcacggc
     4621 tctggataat ctcttccgtg atctcttgga tatccaaacg attcaagaaa cgctttttct
     4681 cctcgatcaa gattgccgta ccatataaag cgacacgacg atagtcaccg ataatacgtc
     4741 ctctaccata cgcatcgggc aagccggtga tgatagccga acgacgtgcg gcaaccatct
     4801 cttccgtata tgcggagaaa acgccctcgt tatgcgtctt acggtacttc gtgaagatct
     4861 ctttcgtcat cgggtctaaa tgataaccgt aggcttccaa gctattctcg accatacgga
     4921 taccaccctt cgggaagata ccacgtttca gcggagcatc ggtttgtaac ccaacgataa
     4981 cctcattctc cttatcaata tagcccggac catatacatc gatcccttga ggtaattttg
     5041 tctcggcgtc ataaactccc ttttctctct cgaccttaaa catctcggtc agcttgttcc
     5101 agaccttacg ggtcttctcg gaagaagcga ctaaaaagga atcatcccct tcataaggcg
     5161 tatagttact ctggataaaa tctcttacat tgatctctct cttccaggtc tcacccttaa
     5221 agtgatccca gtactcattc tcaaatttca taaacaatct tatctaatac cacattttta
     5281 ccggcacaaa ggtaaaactt ttatcctcat gttcctgtaa catttgcgac acccctctaa
     5341 aatccctata aataggtatt aaaaatatac aagaagaaac gggatagtaa tgcgatgctt
     5401 tgcacgaagt ctccatttta ttcactatct ttgcctacag aacgtaaaag ttaatctgga
     5461 tcaaacacat gagaaatatc ctgtttaccg ttttatttat aggaatacta tctttaatcg
     5521 catctcctat ctcactcgcg tctaaatctt tgcataaggc aaatatgatt aatttgtcga
     5581 acaatgccat tatttgcatg catcaagatc cggatggcta tttgtggatc gggacttacg
     5641 acggacttaa cttatacaac ggaaaagata cgtatgtata tcgtttcgaa ttaaataaca
     5701 aaaactctct ttgtagtaat atcattcaca aaatatccga cgcagaaccc ggctttttat
     5761 ggatatcaac ctctttaggt atcaataaat tctcgctaaa gaaacggaaa gtcaccgagt
     5821 cttacccggg atacatggag agtgatctgg tagcgaccga ttcatccggt atcacattag
     5881 ccatttgtaa agaaaaccgg atatcttgtt acaccccatt tagcgatgga ttccgggatc
     5941 tgccgagaga agggataggc cctcaaaccg tacggacttt attcgccgga acagacggat
     6001 atttttattt actattgacc tcgggaatac tgaaaaagtt aacaccggat ttctccaata
     6061 caacttttaa tttactatcg gaagaacgcc aattccataa taaaccgatc ttatccgcat
     6121 ttcatgagaa taaccatatc ttcattgtcg ataccgacaa taagttatat cgccaacagg
     6181 tagacggaag cgggaaagaa ttcctgtttg atctgtctgg aatgacaaat aaatatggaa
     6241 acatcattaa gatatgtacc ttccaatcca atgtatatat cgttttccgt aacggcaata
     6301 ttctagacct aagccaaccg gaaaacacga tagacacggg catcggtatc ttttgcctga
     6361 tgaacgataa aagacaggag attctttggg tagggaccga tggacaaggc atacggatgt
     6421 tttacgataa acccgatctt ttcggctcta tcttactcaa ggatttaccg attaatatac
     6481 agaaccccat acgttcttta tatacagaca atgatcgatc cctttggttc gggacaaaag
     6541 gagacggaat tgtccggata caagcctatg acacttaccc aaacaaaaag gcgattccac
     6601 aaagcgctat cacgcatttc accaccgccg acggattatc cagcaaccgg gtatatagct
     6661 tccagagaag cgaattccat ccttgtatct ggatcggtac ggaaggcccg gggctctgtt
     6721 attattctta taaagaaaat cgaataaaga cgatcccgca gcaagaggac actcccccta
     6781 tccgctatat ccattctatt tgtgaggtaa acgactcgac attatggttg gcgacaaccg
     6841 gcaacggatt actgaaggtt actttacgta tggataaagt cacgcctaca atcagtaaga
     6901 tacaaacctt cccgctaaaa aacggggaga atacctgcaa agagattcaa tccatgatat
     6961 atgataacga ctcgacctta tttctcggga gtcgtggcgg ttatggggtt attagtttta
     7021 acatattcaa ccagaaatat gagttcctgc aaaccaacaa tttaaggaat ccggccattg
     7081 gagacgtgtt atctgtatgc cagaccgagg attctacttt ctatgcaggc gccagctccg
     7141 gacttacccg gattaaattt aaaagaggaa agatacattt acgccaattc gataaaagca
     7201 acgggatcgc aaacgacatg atccatggca ttcatgaggg gaatgatagc tgtatctggt
     7261 taagcaccaa taaaggtctc accaaatata atccccggaa taattttttc cataattatc
     7321 atcaacctta ttttagcgtc acggaattct ctgatgacgc ttattggaaa tgcccatact
     7381 ccgagcgttt attctttgga ggcatcaacg gattagtctg ggtaaataaa caaacggagc
     7441 cggagcatac ctatcaaccc gaattaagtt tcttcgagtt gcaaatggat aaacaaatcc
     7501 ttccattata taaggacatc agccggaacg gtgtaacggt tccggctgat gtgcaatcgt
     7561 taacgattgc gttcgtcgct ccggattaca tcaacgggga gaattacgag tattcgtatc
     7621 agttggtcaa ctataattcc tcttgggaaa aattgcaaaa gacaaacaag gtaactttca
     7681 tgaacctccc gtacggggaa tacttgctga aagtccgtta tcgtaacgat gtcattgatt
     7741 cgtcggcaaa agaatacacc ctacctatca aggtattacc tcctatttat ctaagctcat
     7801 tagctatttt cacgtatctt tttatcggta cggttttaat catcattgcc atctatcgca
     7861 tccattacca aatactaaag aaacagaaac aaatagcaga caagatcaag gaggagcaaa
     7921 aagagaagct atacgaggag tctaagctga atttctttac ccatatcacg catgagttat
     7981 gtaccccgct taccttgatc aatggcgtgg agaattatat ccaagcctat gccgccacct
     8041 caaaagacaa gacattagaa aaatacactt cagtcctccg ggaaaatgta gaggaactga
     8101 acgggcttat ccaagaaatc cttgatttcc ggaaagcgga agacgctgga ttcagtcata
     8161 cgcacatccg aagagtatcc gtatcctctc ttttgcgaac tcaattcgaa tggttttacc
     8221 cactatccga gcaacaccaa atccaattca agatcgatgc tcccaaagag ctttattgga
     8281 atacggattc cgtctatttc aagaagatcc tagcaaatct gatttccaac gcatttaagt
     8341 atacggaaga cgggggcacg gttcgtatct ccttacatga ggaggagaac ttcctcgtcc
     8401 ttaaagttta caacaccggc aaaggaatcg aggaggcaga catgcaaaat attttcgacc
     8461 gatatcgtat ccttggcacg atggataacg acgataacag gcaaaatacg gcacggaatg
     8521 gcctcggctt atttatctgc cacagcctcg tacaatcctt aggtggtaaa atcgacatag
     8581 agagtgaggt cggccaatat gctgaattta cagttacctt accttttggc atcgtagagg
     8641 agagctcaga cgacacgata gacgaagata ttcccgtatc gcttccttcc ccaaacacgg
     8701 atatacaaaa gccgcaaatc tcacatacgg cacaaaaaga gacggaagat aaaccgatga
     8761 tactcgttat cgacgatcat aaagacatcg tctggctaat cacggaaacc ctctcttccg
     8821 aatatcaggt tcaggaagct tataatgcgg aggaggctct ggaattcctc aagcaataca
     8881 ctccctccct tatcatcacc gatatcatga tgcctaatat cgacggattg gaattgatct
     8941 ctcttatcaa ggaaaataga tatacccgtc atatcccgct tattatcgta tctgccaaaa
     9001 tatcagacca agagcaagcg gcaggactta atataggagc ggatgcctat ctaaccaagc
     9061 ctttctcgcc aacagttctc ctatccgtcg tgaaccgatt gatgacaaat caaagagaat
     9121 taaaagagta tttctattct ccggaaagtg cttatcaata tacggaaggg caattattac
     9181 atcaagaaga caaggaattc cttgacgccg taaccgctat catcaaagaa aatgtcagca
     9241 aggaaggact cggtcccgag ctggtagcgg acgcactgaa tataaacacc cgcatcttat
     9301 atcgccgttt caagaaaata tctaccatga cgccgagtga ttttataaag gattataggt
     9361 taaactatgc agcgcaatta ctcgtaaata ccaacatgag cgttcaggaa attatttata
     9421 atgtagggat ttctaacaaa tcatacttct atagggagtt tgcccgtaaa tataacatga
     9481 ctcctaaaga ataccgcaca aaagaggcat aaatcattga ttcctaaata gtgtcataat
     9541 ctaccaaaag agtatcataa tctgccatat gcatttcatg acacttcttc ggtatttcaa
     9601 agcactcttc aattcgttaa gacctattaa tattgctgtc gaataacaaa gcaaaccgct
     9661 tgtgtgtatt cttccttcgg gaagcacatt attaactttt aatttaatgt ttttatgaaa
     9721 aaaaagagtg aaggtaagac gaggaaatgc ctgactttat taggtggacg aacctctttg
     9781 ttactttgtt tatctttaat gtttcagtcc tcttatgcgg ccgaagattc tactgttcct
     9841 gaaatgggaa acatggagat tcatcagatc gcacagcaaa gttcaaccat taaaggtgta
     9901 gtaaaagacc aaaagggtga acctctgatt ggcgttagta ttgttgtgaa aggaaccacg
     9961 aacggaacag cttcggactt tgacggaaat ttcaccttgg atgtgccgga taacagcaca
    10021 ttggtatttt ccttcatcgg cttcaaatcc caagaagttc gttataccgg gcaaaaaaca
    10081 ttgaacatag tcttagctga agactctgag acactagacg aggtagtagt cgtaggttac
    10141 ggttcccaaa agaaaggtga gatcacctca tccgttacca gcgtgaaagc atccgacttt
    10201 aacaaggcac cggtagtgaa cccgatgcaa ttggtggaag gacgtgtagc tggtctgact
    10261 gtatcacgtg gtagcaccga cccgaatggc gaggtaaaag tacagatgcg tggtgcctca
    10321 tctctgaaag gtagcaatga gcctctcgtt attatcgacg gtatgccggg taatatgact
    10381 tctttgaacg ctatcgcacc cgaggatatc gaggcgatcg acgtattgaa agacggttcc
    10441 gcagccgcta tctacggaac ccggggtaat aacggtgtga tcatcgtctc cacgagacgt
    10501 ccgcaagccg gaactactca agtggattac tcaggatata tcatgcacga ggcggtttat
    10561 aaacggccgg aaatcttaaa tggagacgag ttcgtcgctt atggcaagga aaccaacaac
    10621 gccaatatcc gcgactttgg tggacgggat aaccattacg acgctttatt gaataagagt
    10681 aatttcaccc atgtacacaa cttgaccgct accggtggta atggtaagac aaactatcgc
    10741 gcttctttaa attacaaaaa gaatgatggt atgatccgta acaccagccg tgaaacgatc
    10801 aatggctcta tcgccgtgaa ccaccgtgcg tttgatgata aactacagct ttctttcaat
    10861 ctagcaaact ctttcgtgaa agtggacgcg gtttccgatg atgtggataa ggtaggagat
    10921 atccctaatt acggcatatt ataccaggcg atccgtatca acccgacgat gcctatttat
    10981 aaggaagacg gctccttctg ggaaacttac agcggttacg aagatttcaa cccggtagcc
    11041 cgcatatacc agcgtaccaa gaaaaaggaa ttcaagaatt tattggcgaa cttcaaggct
    11101 caatatgaga ttatccccgg tctgacagcc gccgctttct tcgctatgga gaagaacgac
    11161 gcattaacta acgattatag tatgcgtgag gaatatagcc aatataaaga cggtacaaac
    11221 ggacgcgcca aaaaagaata ttatcagaat accaatcgta ctactgaatg gacagcaaac
    11281 tacaatactt ccatcaacgg cgtacacaat attaccggtt tgctgggata cagttaccaa
    11341 gattttgaat acgagcaatt cagcgccgag aacaaaaact tcttgacgga cgtattcggt
    11401 accaataacc tagaagccgg cggttaccta aaagatggta aggccgagat gaagagtaaa
    11461 aaagagacca gcaaactgat cgccttcttc gcccgtgcca actataatta cgacggtaaa
    11521 tacatggcca gcgcctctat ccgccgtgaa ggttccacaa agttcggagc gaacaacaaa
    11581 tgggcttggt tcccctctgt cagcgcaggc tggatgatct ctcgtgagga cttcatggag
    11641 agccaagaag tattcgacgt attgaaattc cgtgccggtt tcggtatcac gggtagtcta
    11701 cctaccgatc catatatgtc tctcgctacc tacggcacag gtgctggagc ttggtacgct
    11761 tacaccggtt catggctaac cgccacttac ggtccgaata tcaacccgaa tccggatttg
    11821 aaatgggaga agaatgagtc cttgaacatc ggtttcgact tcggcttgct aggtggacgc
    11881 ctaaatggta cgatcgattg gtatagtcgt acgactcgcg acttgatcag tagctacaat
    11941 gcccaacagc catccttgat ctacaacacg atcaccacca acgtaggcac gatgagaaat
    12001 agaggtatag aattagcatt aaacgcagag gtcgtaaaga ctaaggattt ctcttacacg
    12061 gctaatttca cgttctcata cgagaataat aaattgacat ctttgtctaa cgacgtgtac
    12121 aaatcttctt acgaggatca atatgacctg ccctctccgg gtaacccggg caaggcttac
    12181 cgcctacaag aaggacagcc gatcgcgtca ttcttcggtt atgtatgcga tggtatcaat
    12241 ccggacggaa cttggaatct tcgcgacata gacggaaagg aaggtctgtc tgacgctgac
    12301 cgtaccttta tcggtaatgg tttgccgaaa ttcaaggctg gcttacagaa cacatttacc
    12361 tataagaact ttgacttcag cttcttcctg cgcggtatgt ttgattatga cgtattgaac
    12421 gagggtgcta tttatttcgg aacgactgtt aatattgatc agtctggcac aaacgtatac
    12481 aaggatgcct tgaagaacaa ggtaacagag caaccattgt tctcttctta ttatctagag
    12541 aaagggaact tcttgaagat cgataacgtg acactaggtt atacattcaa cttcaaaaat
    12601 aataaatatg tgcgcaactt acgtatttat ggtaatgtca ccaatcttgc gactattaca
    12661 ggatactctg gtttaacccc tgacgtaaac gtaacaggac tacaagcagg tatagagaag
    12721 cgcggatctt atcccaccac ccgtaccttc acgtttggcg ttaattttgg attctaatta
    12781 agtaacaata gatttaagac aatacaatga aagctttaaa aaatatatgc gcaatttcat
    12841 tattgctggg agctaccgca tttacctctt gtacggacct gacagaggaa atacatagct
    12901 cggtaatcgc tgagaattat tacaacaatg caggcgaggt aatggccgcc atgatgcgtc
    12961 catggggaca cttctgtgga actatgcaag tagcccaatc gccttggtca tgtaacgagt
    13021 tatcttccga ctgtgccgca tggcctcaaa aaggtcgcca cggctatgac aatggagact
    13081 ggattcgctt acaccgccat caatggattc ctacggatgg tcaagtagtg gatgcttgga
    13141 aaaaattatt tgaaggtatc ggatatgcta acaacttcct tacagataca gagaatatag
    13201 attttgaagc actccaagtt ccaatgtcta aagcacaagc acaagcggag atgcgtgtat
    13261 atcgcgctta ctgttattgg tatgtgatgg atatgttcgg tacggctcca atttgcgaga
    13321 aaatcggtga aatcaatcct tcctccaaat ctcgcacaga gttattcgct tggatcgaaa
    13381 aagagttaaa cgagagtatt ccttctttgt cagagagtaa aacagagacc tacggacgtg
    13441 tatccaaatg gggggcttac gcattattgg ctcgtctcta tttgaatgcg gaaatttata
    13501 ctggacaagc acgctgggat gattgtatcg cagcttgcga tgaattagct aagggaggtt
    13561 tcgcattgga taagaagtgg aacgacactt tccgtgcgga taacgacaag cgatctaccg
    13621 agattatctg gtcaatcgtg tatgatgaag tatatgccaa aggaatgggt tggtatcaac
    13681 gttggttgca ttacgcacac caaactggct gggatttgca atccggtcct tggaacggct
    13741 tggtgacaca accgaccttt tatgactcat tcgctgacaa cgacttgaga aaaattgagg
    13801 gtttcttgat cggtaagcaa tatcctcgca aagtagatga aaacggtaat tactactacg
    13861 acacgaccgc agagcctttg aaaggttcag aggagtacaa tgggcaggat ttggtattcg
    13921 taaactacat taagtccatg accgagggcg aagaaaacag cggcgctcgc tctatcaagt
    13981 atgagatcca accgggtact accggcgata tgaacaacga ctgggtgatg ttccgttatt
    14041 ccgaggttat ctataacaaa gcggaggcct tgatgcgtaa gaacgggggc aaagcaacgc
    14101 aagaagtggt agatatgatc aacagcgttc gtcaacgttc tttcaaggca gaggattggg
    14161 agaaagcgaa atatacgacc gctacattga caatggatga gttcttagcc gaaaaaggta
    14221 gagagtttgc tttcgaagga atccgccgta cagacttggt tcgttttaac aagttcgtaa
    14281 ccacttcttg gtgggacaag actgcatcca acgaaccaaa gcgtaatatc ttccctattc
    14341 cgcaaagaca attggatgct aacgcaaact tatctccgaa cgaggctaac tcattgttct
    14401 aaatatcaac taagtatagt agaaatccat tattaacaaa ttagcacttg acaatgatag
    14461 aggactacta tacttattga tctgaaaata taaaaggtta cctttgtcac tatcaaaggt
    14521 tatccttgga actatcaaag gtgacctttt atgtttcatc cttttctaac taattgatac
    14581 gacatgataa atctcaagaa atcgatgtgt tgcctctttc tggcagccag ctcaacagta
    14641 gcgatcgcac agaccagtgt agttgatctt gtaaacccga tcatcgggac gaatggaatg
    14701 ggacatacgt tcccgggtgc ttgcgtaccc ttcggactcg tacaactcag tccggatacg
    14761 gataccatac cacacaacgt agatggtaaa taccaacctc gctcctacga gtattgtgcg
    14821 ggttatcaac ataaagacag tagcatcgta ggtttcagcc acacccactt cagcggtacc
    14881 ggccactccg acctcgggga tatcttgatt atgcctacca ccggaacgtt gaagctaaac
    14941 cccggaacgg ccacgaatcc cgatggcggt taccgttccc gtttctcgca tggcaccgag
    15001 atatcccgtc ccggatacta cgaggtgatg ctcgccgatt atggcgtaaa ggcacaactg
    15061 accaccaccc aacgggtcgg catccacaaa tacacatacc ctacgaacag tgagaaccaa
    15121 cgcattatcc ttgatatgat tcacgggatc tataactatg acggcaaagt tctttggacc
    15181 aatattcgcg tagagaacga tacgctggta accggctatc gtatcacaaa cggttgggca
    15241 cgtaccaact a
//
