LOCUS       c00025_gnlPro..        13614 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CFELAOPH_25.
ACCESSION   c00025_gnlPro..
VERSION     c00025_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 23:02:40
            Original ID  :: gnl|Prokka|CFELAOPH_25
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13614
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13614
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[771:3614]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      772..3614
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
     cand_cluster    1..13614
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="single"
                     /product="porA"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13614
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="porA"
                     /region_number="1"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     CDS             436..717
                     /locus_tag="ctg25_1"
                     /transl_table=11
                     /translation="MEQIDNLKELINQGDVDTAIKQLDQLLQDSSVEKEKDTLYYLRGN
                     AYRKKGDWKRALDNYQYAIELNPDSPAVQARKMAIDILNFYHKDMFNQ"
     CDS             772..999
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_2"
                     /sec_met_domain="Fer4_7 (E-value: 4.4e-13, bitscore: 41.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 7.4e-10, bitscore: 30.2,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 1.2e-08, bitscore: 26.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 2.7e-08, bitscore: 25.5,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.6e-06, bitscore: 18.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKIKGAIVVDTERCKGCNLCVVACPLDVIALNKEVNMKGYNYAW
                     QVKEDTCNGCSSCATVCPDGCISVYKVKVE"
     CDS             1011..2093
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_3"
                     /sec_met_domain="PFOR_II (E-value: 7e-28, bitscore: 88.8,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 3.5e-50, bitscore: 162.6,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEEVVLMKGNEAIAHAAIRCGADGYFGYPITPQSEVLETLAELK
                     PWETTGMVVLQAESEVAAINMVYGGAGSGKKVMTSSSSPGVSLKQEGISYLAGAELPCL
                     IVNVMRGGPGLGTIQPSQADYFQTVKGGGHGDYKLIALAPASVQEMADFVALGFELAFK
                     YRNPAIILADGVIGQMMEKVVLPAQKPRRTKAEVIEQCPWAATGKAKDRKPNIITSLEL
                     KPEAMEINNLRFQAKYREIEENEVRFEEINCEDAEYLIIAFGSMARIGQKAMELAREKG
                     IKVGILRPITLWPFPTKAIAAYADKVKGMLVTELNAGQMIEDVRLAVNGKVKVEHFGRL
                     GGIVPDPDEIVTALKEKIIK"
     CDS             2101..2274
                     /locus_tag="ctg25_4"
                     /transl_table=11
                     /translation="MNPDKIRNVLNILFMILAVAAIITYFVAKDDFKMFIYVCGAAIFV
                     KLMEFFIRFTNR"
     CDS             2287..3051
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_5"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5e-26, bitscore:
                     83.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKEEIIKPENLVYKKPTLMNDNAMHYCPGCSHGVVHKLIAEVIE
                     EMGMEDKTVGISPVGCAVFAYNYLDIDWQEAAHGRAPAVATAVKRLWPDRLVFTYQGDG
                     DLACIGTAETIHALNRGENITIIFINNAIYGMTGGQMAPTTLVGMKSSTCPYGRDIELH
                     GYPLKITEIAAQLEGTAYVTRQSVQSVPAIRKAKKAIRKAFENSMNGKGSNLVEIVSTC
                     SSGWKMTPEKANKWMEEHMFPFYPLGDLKDKE"
     CDS             3072..3614
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_6"
                     /sec_met_domain="POR (E-value: 2.8e-36, bitscore: 117.0,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEEIIIAGFGGQGVLSMGKILAYSGLMEGKEVTWMPAYGPEQRG
                     GTANVTVIVSDDKISSPILSKYDAAIILNQPSLEKFESKVKPGGILIYDGYGIINPPTR
                     KDIKVYRIDAMDAANEMNNAKAFNMIVLGGLLKLRPIVTLENVIKGLKKTLPERHHHLI
                     PMNEEAIKKGMELIREV"
     CDS             3736..5787
                     /locus_tag="ctg25_7"
                     /transl_table=11
                     /translation="MRRILLLYIIFSVIGLTTVHAQFDNGRQRVDENGYDQYGNQVDPA
                     MIPDRLDSANVEVQGLPPKLYMWRINNQLGDRTIIPADTAYHHFQNSNLTEGLTGHYNY
                     LANMGSPRMSRIFFERRDPEPTIFMEPFSSFFIRPTEFNFTNSNVPYTNLTYHKAGNKI
                     NGEERFKSYFSVNVNKKLAFGFNIDYLYGRGYYNNQNTAYFNAAIFGSYIGDRYQMQAI
                     YSNNYLKTNENGGIEDDRYITAPEEMAQGQREYESTNIPTVLSATTNRNHDFYVFLTQR
                     YNLGFSRDIPQAENDTTPAKQEFVPVTSFIHTIQVERARHSFNSDDDMREKNYYQNTYL
                     EPDNPIARDSTTYMGIKNTIGIALLEGFNKYAKAGLTAFASYKISKYTLMNMEGNPLPD
                     KYNENEIFVGGELSKREGNVLHYHAIGEVGLAGKAIGQFNVKGDIDLNFPLWKDTVSLI
                     ARGEVSNKLAPFYMRHYHSKHFMWDNDMDKEFRTRIEGELSIARWRTRLKAGVENIKNY
                     TYFNQQAVPEQKSGSIQVLSASLNQDFKLGIFHLDNEVTWQKSSDQTVLPLPDLSLYHN
                     FYMQFKLAKKVLSVQLGADVRYFSKYNAPAYMPAIQNFYLQPENDQVEIGGYPIVNVYA
                     NLHLKRTRFYVMMYHVNQGMSSPNYFLSPHYPINPRVLKFGLSWNFYD"
     CDS             5805..6644
                     /locus_tag="ctg25_8"
                     /transl_table=11
                     /translation="MVTRPKLRLSRYLVPVIIVLAIIFSIRQCGNQEKPSGHPRDYAAI
                     AKEGILRVATEYNSISFYVDGDTVSGFHYELIQAFAYDKGLKTEITPLMSFEERLEGLS
                     EGRYDVIACGILATSELKDSLLLTSPITLNKQVLVQRKENGENDSLYIRNQLDLAGRTL
                     HVVKGSPSILRIQNLGNEIGDTIYIKEIDKYGSEQLISMVAHGDIDYAVCDESIARAAA
                     DSIPQIDINTAISFTQFYSWAVSKQSPALLDSLNTWLDKFQKEERYQKIYKKYYDKE"
     CDS             6631..10821
                     /locus_tag="ctg25_9"
                     /transl_table=11
                     /translation="MIKNNLITLHIKRKQLPIFYLFFFIFLLSSGNSRLYAEENRAFNF
                     STLNLNNGLSQLSVLDICQDDKGYIWFATRNGLNKYDGTHFTIYKHSNRDNNSLSDNHI
                     TKLLPDNVRGGLWVGTNNGLNYLDPKTNLITNYQLADYPELPSNSILSLCLDKSGKLWV
                     GTRLGLCFWQPENKTFKLVTLDGQLDKESITSLYIDKQERIYIGTHDKGLLICDKNLNV
                     TQKLTKESTPALSDNAISCIFEDSHQQIWIGTDMKGLNKWNPDKQTVSAFFEHNSGLTD
                     NYIRCLQEQNQQLIIGTFDGLSILNLTDDSITKYNKFEANRNNLSHFSVRSLCVDRAGT
                     LWVGTYSGGVNYYNPLNNRFVFYHPLGNSEQKLYNIFGPMVYSTGSLWIATEGGGLLQF
                     NPATKEYTNYLLEERPVGMHNKNIIKSLMIERESIWCGTNNGGLYRFHIPTKRFSLIHQ
                     FNEKNLGIYSIYRDSNEDIWLGTTSRQGLVRITKDKKITRKFPIGEKGETISFSSIRAF
                     LPLRKNVYLIGTRSFGLYEYDVEKKTLIQYSTEEKDPSRQLENNYVTSILRKKNGEIWI
                     STFGAGIYQYQEGKGIVRHIGTEEGLTNEEVYTLIEYNQNIWASIDNGIAEINTKTGQV
                     HVYDCFAGLETLEFTPQGGICLPNGEVYFSGSNGFLSFAPRSLIKNNMMPPVVLTQLTV
                     NNKVIQPGDQSHLLDANPDDTETITLAYNQNNFSIAYCALNYILHEQNQYAYKLVGHDE
                     DWNHVGTRKEAYYTNIAPGKYIFHVIASNNDDVWNTQGKTLEIIILSPWWKTPWAYMIY
                     ALLFIGITYTIGYYMYSKHKLELNLRMRQMEKQRMEEFHQTKIRLFTNFSHELRTPLTL
                     IISPIDELVRQAEVPHFIKTKLDLVLKNARRLLLLVNQLMDLQKNQSGSLTLSLTHTDL
                     NAFLLEIYYTFKQIAESKQITFLYEAPEGEIPACFDQSLLEKAVFNLLSNAFKFTPPGE
                     TVTLRFIAALNKESLQQRFGKNISTDPTFVLSDDSNNYFVIQVADTGKGIPETARTHIF
                     DPFYQVSAPQTANDNVNGTGIGLSLTQSVVHLHQGAISVDSNRPKGSIFTIILPNNEQP
                     ESMEENVINNLSENEREEQEVVSQSEESAEELPYLTGKTILLVEDNEDIRSYVKEHLQR
                     HYRVLEAGNGEEAFQIVLKEFPDLVVTDIMMPGVDGLELCAMIKNDLQTGHIPVILLTA
                     RTMVMHVKEGFLSGADDYVVKPFNIDVLLVRIYNLLLQREKLKSMYGKNFSLQSMGIET
                     TSADDKFMQKLFEIIQDHLDNPDLKVDMICDEMGFSRSNFYRKLKAVTDLSLNDLIRHK
                     RLEVAAQLLKKADMNVTEVSIATGFSTLAYFTKCFKSAYGVSPTEYVKGQPEE"
     CDS             11141..12385
                     /locus_tag="ctg25_10"
                     /transl_table=11
                     /translation="MKHYLLALSIGTAFLVGCQSPQKQNLIDSNFAFAEQQLKYAFPKI
                     DEARANESQESKEKRIAKQWGELTNPRNTEPDGSLRLVPSKDWTSGFFPGELWYVYEYT
                     HDPFWKEKAEKHTEMLEREKKNGTTHDMGFKMYCSYGNGYRLTGNPTYKDILIESARTL
                     ITRYKPNVGCLRSWDHHADQWECPVIIDNMLNLELLFWASRETNDSTFYNIAVNHARTT
                     MKNHFRDDYSTYHVVNYDTITGNPICKVTHQGYADSSAWARGQAWALYGYTMCYRETGL
                     PEFLEQAKHIERYIFTHPNLPEDLIPYWDFNAPEIPNEPRDASAATCIASALYELSTYV
                     PEYKALYKEEADRILENLTAHYRAKPNGDNGFLLLHSTGSKPHNSEIDVPIVYADYYFL
                     EALIRKNKLEKEQKL"
ORIGIN
        1 atcattagcc tttttatttt aatacactat atagaatcgc ggagacgctt acctttcacg
       61 ttttttcttt ttcaaacagt ccctttcaac tacgctcgct gctacaacga gcaatgtccg
      121 aaagcttgta actgcctgcg tcggatggct gcacttctca ctaccgctga cacgtcctac
      181 atcagcatca taaacccaat gtgtattccg gccaccggca ttgactgtcc ccacttccaa
      241 aacgcagaaa agatacatgt ggcatggggt atcagccacc tgctggataa cgtaccttat
      301 aaggacggaa caaactccgc ctctactata caatatgcaa taaactcaaa acgttgcaaa
      361 tttccgtcct catttgccct gtttacataa ataaaaacta tctttgcgtt tcagaatccc
      421 gaaagacgaa aagaaatgga gcaaatagac aacctaaaag agcttatcaa tcagggggat
      481 gtggacacag cgattaagca attggaccag cttctccagg acagttctgt cgaaaaagag
      541 aaagatactc tttactattt acggggaaat gcctaccgaa agaaaggaga ttggaagcgg
      601 gcgctggaca actaccagta tgccatcgag ctcaatccgg acagtcctgc cgttcaggcc
      661 aggaagatgg caatagatat cctcaacttc taccacaagg atatgttcaa tcaataaaag
      721 agatgtataa tcaataaccg tactcaaaga taacgtaata aaataaagat tatggcaaaa
      781 atcaaaggag caatcgtagt cgacacggag cgttgcaaag gatgcaacct gtgtgtagtg
      841 gcgtgtccgc tcgatgtaat cgccctcaat aaagaggtaa acatgaaagg ctataactat
      901 gcctggcaag tgaaggaaga tacctgtaac ggatgcagct cgtgtgcaac ggtttgtccg
      961 gacggatgta tttcagtgta taaagtaaaa gtagaataaa agaaaagaat atggcagaag
     1021 aagttgtatt aatgaaagga aacgaagcca tcgcccacgc agctatccgt tgcggtgccg
     1081 acggttactt cggttatcct attactcccc aatcggaagt gttggaaacg cttgccgaac
     1141 tgaaaccgtg ggaaacaacc ggcatggtag tactccaggc ggaaagtgaa gtggcagcta
     1201 tcaatatggt atatggaggt gcaggtagcg gaaagaaggt aatgacctca tcttcaagtc
     1261 cgggtgtgag cttgaaacaa gaaggaatct cttatttggc cggtgccgaa cttccttgtc
     1321 tgattgtgaa tgtaatgcgt ggcggtcccg gactgggaac tatccaacct agccaggctg
     1381 actacttcca gacagtaaaa ggtggtggtc atggagacta caaactgatt gccctcgctc
     1441 cggcatccgt acaggaaatg gcggatttcg tagcattagg attcgaactg gctttcaaat
     1501 accgtaatcc ggctattatc cttgccgacg gtgtgatcgg tcagatgatg gaaaaggttg
     1561 ttcttcctgc acaaaagcca cgccgcacga aagcagaagt aattgaacaa tgtccatggg
     1621 ctgctaccgg aaaagcaaaa gaccgcaaac cgaatattat cacttccctt gaattgaaac
     1681 cggaagcaat ggaaatcaac aacctccgtt ttcaagctaa atatcgtgaa attgaagaaa
     1741 atgaagtacg cttcgaagag atcaactgcg aagatgcaga gtatttgatt atcgcattcg
     1801 gttcaatggc acgtattggc cagaaagcaa tggaactagc tcgtgaaaaa ggaattaaag
     1861 taggtatcct tcgcccgatt acactgtggc cgttcccaac caaagcgatt gctgcatacg
     1921 ctgataaagt aaaaggtatg ctcgttacgg aactaaatgc cggacagatg attgaagatg
     1981 tccgtctcgc tgttaacggt aaagtaaagg tagaacattt cggacgtcta ggtggcatcg
     2041 ttcccgatcc ggatgaaatt gtaactgcct tgaaagaaaa aataatcaaa taacgaaaca
     2101 atgaatcccg ataaaataag aaacgtactg aacatcctat ttatgatatt ggctgttgca
     2161 gccatcatca cctactttgt agcaaaagat gatttcaaaa tgtttatcta cgtatgcggc
     2221 gcggcaatct ttgtcaagct gatggagttt tttatacggt tcaccaacag ataaggagat
     2281 gaagttatga ctaaagaaga aataatcaaa cccgagaatc tggtttacaa aaaaccgact
     2341 ctgatgaacg ataacgccat gcactactgc ccgggttgca gtcacggtgt ggtacacaaa
     2401 ctcattgccg aagtcattga ggaaatgggt atggaagata aaactgtagg aatctctccg
     2461 gtgggatgtg cagtgtttgc ctacaactat ctcgatattg actggcagga agcagcacac
     2521 ggacgtgctc ctgctgtggc aactgctgtg aaacgcctgt ggccggaccg ccttgttttc
     2581 acttatcagg gtgacggtga cttggcttgt atcggtacag ccgaaacaat ccacgctttg
     2641 aaccgtggtg agaacatcac gattatcttt atcaataatg cgatctacgg tatgacaggc
     2701 ggccagatgg ctccgactac actagtaggc atgaagagtt cgacttgtcc ttacggacgt
     2761 gacattgaac ttcatggcta tccattgaag attactgaaa tcgcagccca actggaagga
     2821 actgcttacg taacccgtca gtccgtacaa tccgtaccgg ctatccgtaa ggctaaaaag
     2881 gcaatccgca aggcttttga gaactccatg aacggtaaag gatccaacct ggtagaaatc
     2941 gtttctactt gtagttcagg ctggaagatg actccggaga aggcgaacaa atggatggaa
     3001 gaacacatgt tcccattcta tccgctgggt gatttaaaag ataaagaata acgctaaaag
     3061 tcaacagaac aatgaaagaa gaaataatta tagcaggatt cggtggacaa ggcgtattgt
     3121 ctatgggtaa gattctggca tattccggtt tgatggaagg caaagaagtg acctggatgc
     3181 cggcttacgg tcccgaacaa cgaggaggaa cagccaacgt tacagttatt gtaagcgatg
     3241 acaaaatatc ctcaccgatt cttagtaaat acgacgctgc catcattctg aatcagcctt
     3301 cactcgaaaa gtttgaaagc aaagtgaaac ccggcggtat cctgatttat gacggttacg
     3361 gaattatcaa ccctcctacc cgtaaggata ttaaggtata tcgtatcgac gcaatggatg
     3421 cagccaacga gatgaacaat gccaaagcat tcaacatgat cgtacttggc ggattattga
     3481 agcttcgccc catcgtaacg ctggagaatg ttatcaaagg acttaagaaa accctgccgg
     3541 aacgccacca tcacttgatt cctatgaacg aggaagctat caaaaaaggt atggagttaa
     3601 tccgtgaggt ttaattaaca gataatgtac aatggataat tgataattat tagctacgta
     3661 tagtacgtat gcaacataat tttcaattat ccattatcat taaatcaatt aaagtaagta
     3721 tctttgcctc caattatgag acgaatctta ctattatata taatcttttc cgttataggt
     3781 ttgacaactg tccatgcaca gttcgataat ggtcgccaga gagtggacga aaacggatac
     3841 gaccaatacg gtaaccaggt ggaccctgcc atgattccgg acagactgga tagtgcaaat
     3901 gtagaagtac aggggttacc tccgaaatta tatatgtggc gtattaataa tcagttgggc
     3961 gaccggacta tcatcccggc ggatactgct tatcaccact tccagaattc aaatcttacc
     4021 gaaggactta ccggacatta taattatctg gccaatatgg gttctccccg tatgtcacgc
     4081 atcttctttg aacgtcgtga tccggaacct actatcttta tggagccttt ctccagtttc
     4141 tttattcgtc ctacggagtt caatttcacc aatagtaacg taccttatac caatctgacg
     4201 tatcataaag ccggtaataa aataaacgga gaagaacgct ttaagtctta tttctctgtc
     4261 aatgtaaaca agaagctggc tttcggtttt aacatagatt acttgtacgg acgaggatat
     4321 tataataacc agaatacggc ttatttcaat gcggcaattt tcggtagtta tattggcgac
     4381 cgctatcaga tgcaggcaat atacagcaac aattacctca agacaaatga aaacggaggt
     4441 attgaggacg accgatacat cactgcgcct gaagagatgg cacaagggca aagggaatat
     4501 gaatcaacca atatcccgac cgtactaagt gcaacaacca accgtaatca tgacttttat
     4561 gtattcctga cccaacgtta caatttggga ttcagccgtg acataccgca ggccgaaaat
     4621 gacactactc ccgccaaaca agagtttgtg ccggtcacta gttttataca taccattcag
     4681 gtagagcgtg cacgtcatag cttcaactct gatgatgaca tgcgtgaaaa gaactattat
     4741 caaaacacct atttggaacc ggataatccg attgccagag acagtactac ctacatgggt
     4801 atcaagaata ccataggtat tgctctactc gaaggattca ataaatatgc caaagcgggt
     4861 ctgacagcat tcgcttccta taaaatcagc aagtatactc ttatgaatat ggagggtaat
     4921 ccgttgcccg acaaatacaa tgaaaatgaa atatttgttg gaggcgaatt atccaaacgt
     4981 gaaggaaatg tacttcatta ccatgccatt ggtgaagtgg gactcgccgg aaaagcaatc
     5041 ggacaattca atgtgaaagg agatatcgac cttaactttc cgttatggaa agacactgtg
     5101 agccttatag cccgtggtga agtcagcaat aagcttgcgc ctttctatat gcgtcattat
     5161 cattccaaac acttcatgtg ggacaatgat atggacaaag aatttcgtac ccgtattgaa
     5221 ggagaattaa gcattgcacg ttggagaaca cgtttaaagg cgggagttga aaacataaag
     5281 aactacactt atttcaacca acaagcagtg ccggaacaga aaagcggaag tatacaggtg
     5341 ttgtcagcaa gtcttaatca ggacttcaag ctgggaatct tccatttaga taatgaagta
     5401 acttggcaaa agtccagcga ccagaccgtg cttccgttgc ctgatctatc gttgtatcac
     5461 aacttctata tgcagttcaa gctggcaaag aaagtactta gtgtacaatt gggtgccgac
     5521 gtgcgttatt tcagcaaata caatgcaccc gcttatatgc cggctatcca aaacttctat
     5581 ttgcaaccgg aaaatgacca ggtagagata ggaggttatc cgatcgtgaa tgtatacgca
     5641 aacttacatc taaagcgtac acgtttctat gtaatgatgt atcacgtgaa tcaaggtatg
     5701 agcagcccga attacttctt gtctcctcac taccctatca acccgcgtgt actgaaattc
     5761 ggtctttcat ggaatttcta tgattaacaa aatctatatg gcttatggta acacgcccca
     5821 aattgagact gtcccgatat ttagtgcccg taatcattgt attggcaatc atcttttcta
     5881 tccgccaatg cggtaatcaa gaaaagccgt caggacaccc gcgtgattat gcagccattg
     5941 ccaaagaagg tatattgcgt gtagcgactg aatataactc gatcagtttc tacgtggacg
     6001 gtgataccgt ttccggtttc cattacgaac tgatacaggc ttttgcctat gacaagggat
     6061 taaagaccga aataacaccc ctgatgagtt tcgaagaacg gctggaagga ttaagcgagg
     6121 gacgttatga cgtaattgct tgcggcatat tagctaccag cgaactgaaa gactctctgc
     6181 ttctcacctc tcccatcacg ctcaacaagc aagtgctcgt gcaacggaaa gaaaacggag
     6241 aaaacgactc actctatatc cgtaaccaac tggatttggc cggacggaca cttcacgtag
     6301 taaaaggctc tccctccatc ctgcgtattc aaaacctggg aaatgaaatc ggagatacca
     6361 tttatatcaa agaaatagat aaatacggtt ccgaacaatt aatctcaatg gtagctcatg
     6421 gagatatcga ctatgccgtt tgcgacgaaa gtatcgcacg cgcggctgcc gattccatcc
     6481 cgcagataga tataaataca gctatcagct ttacacaatt ctactcatgg gcagtcagca
     6541 aacaatcacc cgctttactc gatagtttga atacatggct ggataaattc caaaaggaag
     6601 aaagatacca aaagatttat aaaaaatact atgataaaga ataaccttat tactttacac
     6661 attaaaagaa aacaactacc tattttttac ctatttttct tcatctttct attgtcttcc
     6721 ggtaactccc gtttatatgc agaagaaaac cgggcattca acttttcaac tcttaatctg
     6781 aacaacggat tatcccagtt gtccgtgctc gacatttgcc aggatgacaa aggatatata
     6841 tggtttgcca cccgcaacgg cctcaacaaa tatgacggta cacatttcac catctacaaa
     6901 cacagcaacc gggataacaa ttccttgtca gacaatcata tcaccaaact acttccggac
     6961 aacgtacgcg gagggctttg ggtgggtacc aataacggac tgaactatct tgatccgaaa
     7021 acaaacctca tcaccaacta ccaactggca gattatccgg agcttcccag caatagcata
     7081 ctttctctct gtctggacaa atccggtaag ctatgggtag gaacacgcct cggactctgc
     7141 ttttggcaac cggaaaacaa gacattcaag ctggtaacat tggacgggca actggacaaa
     7201 gaatctatta cttctttata tattgataaa caggaacgaa tctatatagg tacacacgat
     7261 aaaggtctat tgatttgtga caagaacctg aatgtcaccc aaaagctaac taaagaaagc
     7321 actccggctc tctccgataa cgccatcagt tgcatattcg aagactctca tcagcaaata
     7381 tggataggca cggatatgaa ggggctgaat aaatggaatc cggataaaca gacagtctct
     7441 gccttcttcg aacacaacag cggattgaca gataattata tccgttgtct tcaggaacaa
     7501 aaccaacaac tgattatcgg aacattcgac ggtttgagta ttctcaatct gacggatgac
     7561 tctattacca aatacaacaa gttcgaagca aaccggaata atttaagcca tttctcggtc
     7621 cgcagtttat gcgtagaccg tgccggaaca ttatgggtag gcacctactc cggtggagtc
     7681 aattactaca atccgctcaa caaccgtttc gtattctatc accctttggg gaacagcgaa
     7741 cagaagctat ataacatttt cggaccgatg gtatatagta caggttctct ttggatcgca
     7801 acagaaggag gaggattgct acaattcaac ccggctacca aagaatacac caattaccta
     7861 ctggaagaac gtcctgttgg tatgcacaac aagaatatca tcaagtcatt gatgatagaa
     7921 agagaatcca tctggtgcgg cacaaacaat ggagggttat accgtttcca tattccgact
     7981 aaacgcttct cgcttattca ccagtttaat gaaaagaacc tgggtattta tagcatctat
     8041 cgggactcga atgaagacat ttggctaggg actacttcac gtcagggact agtcagaatt
     8101 accaaagata aaaaaataac gcgcaagttc cccatcggag agaaagggga aacaatcagt
     8161 ttctccagca tccgggcatt tttgcctctg cgcaagaatg tatatctgat cggaacacgt
     8221 tcattcgggc tctatgagta cgacgtagaa aaaaagaccc tcatacaata ttcgacagag
     8281 gagaaagatc catcccgtca actggaaaat aactacgtaa ccagtattct aagaaagaag
     8341 aacggagaaa tatggatcag cacttttgga gcaggtattt accaatatca ggaaggtaaa
     8401 gggatcgtgc gtcatatcgg tacggaggaa ggactgacta acgaagaggt ctatacttta
     8461 atagaataca accagaatat atgggcaagt attgataatg gcattgccga aatcaacact
     8521 aaaacgggac aagtgcacgt ttatgactgc ttcgccggcc ttgaaacgtt agaatttact
     8581 ccgcaaggag gcatttgcct ccctaatgga gaagtttatt tcagcggcag taatggattc
     8641 ctgtcctttg ctccccgctc gttgataaaa aacaatatga tgccgccggt agtactcacc
     8701 cagttgaccg ttaacaacaa agtgatccaa ccgggcgatc agagtcattt gctggatgcc
     8761 aatcccgacg acacagaaac catcactctg gcatacaatc aaaataactt ctccattgca
     8821 tactgtgcgc tcaattacat tcttcacgaa cagaaccagt atgcttataa attagtggga
     8881 cacgatgaag actggaatca tgtgggaacc cgtaaagaag cctattatac caatatcgct
     8941 cccggcaaat acatctttca tgtcattgcc tccaacaacg acgatgtatg gaacacccag
     9001 ggaaaaacgc tggaaatcat cattctttct ccctggtgga aaaccccatg ggcttatatg
     9061 atctatgcat tattatttat aggaatcacc tacaccatcg gttattacat gtacagcaaa
     9121 cataagctgg aactcaacct gcggatgcgc caaatggaaa agcaacggat ggaagagttt
     9181 caccaaacca aaatccggct ttttaccaac ttctcacatg aattgcgtac tccgttgact
     9241 ctaatcatca gtcctattga cgaactggtg cgccaggcag aagtcccgca ttttatcaaa
     9301 actaaactag acttagtttt gaagaatgcc cgtcgtttgc tcttactggt caatcaattg
     9361 atggatttac aaaagaacca aagcggcagc ctcacactaa gtttaaccca tacggatttg
     9421 aatgcattcc tgcttgaaat ctattatact ttcaagcaaa tagcggaaag caagcaaatc
     9481 acgttcttgt atgaagctcc ggaaggagaa atcccggcat gttttgacca gagtttattg
     9541 gaaaaagcag tattcaacct actttcgaat gcgtttaaat tcacgcctcc gggagaaact
     9601 gttaccctgc gattcattgc agcactcaat aaagagagcc ttcaacaacg gttcgggaaa
     9661 aatatatcca ccgatccgac tttcgtcctc tccgacgata gcaataacta cttcgttatt
     9721 caggtagccg acacgggaaa aggaattccg gaaactgccc gtacacatat tttcgatccg
     9781 ttctatcaag tcagcgctcc tcaaacagcc aatgataatg taaacggaac aggtatcggg
     9841 ctaagtctga cccaatccgt cgtacatttg catcaaggtg caatcagcgt cgattccaac
     9901 cggccgaaag gaagtatatt caccattata cttccgaata acgagcaacc agaatcaatg
     9961 gaagaaaacg tgataaacaa tctatccgaa aacgaacggg aagagcaaga ggttgtcagc
    10021 cagtcagagg agtccgccga agaacttcct tacctgacag gcaaaacaat cctgcttgta
    10081 gaagacaatg aggatatacg cagttatgtg aaagaacatc tgcagcgtca ttatcgggta
    10141 ctcgaggccg gaaacggcga agaagccttc cagattgtat tgaaagaatt tcccgattta
    10201 gtggttacgg atataatgat gccgggagta gacggactgg aactctgcgc aatgattaag
    10261 aatgatttgc agactggcca tattccggtc atcctgctca cagcccgtac aatggtgatg
    10321 cacgtcaaag aagggttcct ttcaggagca gacgattatg tagtgaaacc tttcaatata
    10381 gatgtgttgc tggtacgaat ctataatctg ttgttacagc gggaaaaatt aaaatccatg
    10441 tacgggaaaa acttctcact gcaatcaatg ggtatcgaaa cgacctctgc cgatgataaa
    10501 ttcatgcaga agttattcga gatcatccaa gatcatttgg ataatccgga cttaaaagtg
    10561 gatatgatat gtgatgaaat gggattcagc cggagtaatt tctaccgcaa gctcaaggcg
    10621 gtaacagatt tatccctgaa cgacctgatt cgccataaac gtctggaggt agctgcgcaa
    10681 ctacttaaaa aggcggacat gaatgtgacg gaagtttcaa tcgctaccgg tttcagtacc
    10741 cttgcttatt ttaccaaatg tttcaaatca gcctacggag tttcgcctac cgaatacgta
    10801 aaaggacaac cggaagagta gttctaaatt ggttttataa atgggaattt tcaggtacgg
    10861 attacacggt tttctgaaat atgattgcac aaagcaacag cgtaatccgt gtaatccgtg
    10921 cctaaattaa aatgatcctt ttaattatga tgcagtactt atcacatagt ttgcaaaatc
    10981 atcccagatt ataaaaaacg tcccaagagc gatatagaag cgattgtccc aatgaagttg
    11041 ggatgatttt gcaaatttac ggcacagctg gacaagccct ttttattccg tttccataca
    11101 tttgcaacat cgacttagaa ataataatat ggaaacaaat atgaaacatt atcttttagc
    11161 acttagcatc gggacagcat ttttagttgg ctgtcagtct ccccaaaagc aaaacctgat
    11221 tgattctaat tttgcatttg ccgagcaaca actcaaatat gcttttccta aaatagatga
    11281 agcacgcgcc aacgaatcac aggaaagcaa agaaaaaaga attgccaaac aatggggcga
    11341 actgactaat cctcgtaata cagaaccgga tggttctctg cgtctcgtcc cttccaaaga
    11401 ctggaccagc ggattctttc ccggtgaact ctggtatgta tatgaatata cacacgatcc
    11461 tttctggaaa gagaaagcag agaagcatac agaaatgctg gaacgcgaaa agaagaacgg
    11521 cactacccac gacatgggat tcaagatgta ttgcagctac ggcaatggct atcgcctgac
    11581 cggtaatccc acctataaag atatactgat cgaatcagca cgtacgctca ttacccgcta
    11641 caagccgaac gtaggttgcc ttcgttcctg ggatcaccat gccgaccaat gggaatgtcc
    11701 cgttatcatc gacaacatgc tgaatttgga attactattc tgggcttccc gcgaaacgaa
    11761 tgactccacc ttttataata tagcagtcaa ccacgcacgt acgaccatga aaaatcactt
    11821 ccgtgacgat tacagtacgt accacgtcgt aaactatgat acaatcaccg gcaaccccat
    11881 ctgcaaggta acccatcagg gatacgccga ctcatcggca tgggcacgcg gacaggcatg
    11941 ggcgctgtat ggctacacga tgtgttaccg cgaaaccgga ctccctgaat tcctggaaca
    12001 agcgaagcat atcgaaagat atatcttcac ccaccccaac ctgccggaag acctgatacc
    12061 ttactgggat ttcaacgctc cggaaattcc taacgaaccg cgggatgcgt ccgcagccac
    12121 ctgcatcgct tccgcactct atgaactaag tacctacgta ccagaatata aagcccttta
    12181 caaagaagaa gccgaccgga ttttagagaa cctcactgcc cactaccgtg cgaaaccaaa
    12241 cggcgacaac ggttttctac ttctccacag taccggctcc aaacctcaca acagcgaaat
    12301 tgatgtgcct atcgtatatg ccgactatta tttcctcgaa gcattgatac ggaaaaacaa
    12361 actggaaaaa gaacagaaac tataacgatc atcatctata agaaccatga aaaagctact
    12421 tatctatata ctgacagcct ttaccgtact tacccttccg gcaagtgcca agattcccgc
    12481 cagccaacga atccggctga ccgaccaatg ggaatatctc aaaggtgatc tcggaagtat
    12541 ttgggaagcc gtacgtgcag tcgcccccgg ttcttcggaa gctgtaccca tttggcagcc
    12601 agttaccctg ccccactgtt tcaacgcgga agatgccgta gacccggacg taaactatta
    12661 ccagggtccc ggatggtatc gcaccctgct cgatattcag aacccggccg ccaacggccg
    12721 cacgatcctc gaatttgaag gagccggaca gaaaacagaa gtatatatct acacccgtaa
    12781 agtcggcagc cacgtaggag gttacgatga atggagcgta gacatcacag aagcaatccg
    12841 taaagcatta gccgatcccg attgccgcaa gcggttcaac ggcaaagtac ctttgtccat
    12901 ccgttgcgac aattcaagag atacagaaat gattccttcg gatttatcag acttcaacgt
    12961 atacggagga ctttaccgct acgtaaacct gatttatcag cccgcccttt cttttgcaag
    13021 ttttaaactg gaaaccccgg tgcagaagga cttgaagagc gcaacactga aagtgcaagc
    13081 caacttctac aatccgaatg acactcgcca agctacggtt cgcttcactc tgaaagatcc
    13141 gaacggaaag aaagtgaccg aacaaaccgc cacagacatt ctaccattgg gagaagtaca
    13201 cctgtttgac atcgctatca agaatccgat gctttggagt cctgaccagc cacagctata
    13261 cacttgtgag tttaccctcc aaacagccga aggcgaacag acagtaacag aacaagtagg
    13321 tttccgccac ttcgaatttg tagactacgg tcctttcaag ctaaacggaa aacgcttgtt
    13381 attaaaaggt actcaccgcc acgaagacca tgcaggtgta ggagccgcca tgacagaaga
    13441 gcaaatggtg acggaaatga aactcatgaa agaaatgggt gtcaacttca tccgcctggg
    13501 acattaccag caatcaaaca tcatccttcg cctgtgtgac gaattaggta tcctcgtgtg
    13561 ggaagaaatc ccctggtgcc gtggcggatt gggtggagaa acttataaaa taca
//
