LOCUS       c00011_gnlPro..        14497 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IIJCMEKJ_11.
ACCESSION   c00011_gnlPro..
VERSION     c00011_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 20:19:13
            Original ID  :: gnl|Prokka|IIJCMEKJ_11
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 50720
            Orig. end    :: 65217
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14497
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[60720:63715]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12995
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..14497
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14497
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(1157..2749)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg11_50"
                     /sec_met_domain="LysM (E-value: 9.8e-08, bitscore: 24.1,
                     seeds: 155, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTKIRNGGLFLEFQKIKLHRSEKNRAAVTQITLDDDYNVPDYRQ
                     DIVKVIKERGELRFDEVKAMEGAAWIKGSLLFKVLYRSDKQEGKISCLRGEIPFQERLN
                     MDGLSEYDAVHATGDMEDLTIGVINSRKLNVRAVIVLTASSEKEVDEELTCELSDGSSY
                     EQNIVEKEALKLLVVRRDICRQKSEAVLPSSKPNIREILWQSMQLRNVESRLVEGNIRL
                     SGEILVSILYNDEEEGEHLSWYETTVPLDAQAECGVMEDDCIWQVQMVPLTMELEVKPD
                     YDGEERILVMELALDTHIRIWKEEKIRLLTDLYSLQKEVKPVFRECPLERLLVKNAAKC
                     RMTEQMELKEDKEKVLQICSCEGKVLLERQEIKPDGVLAEGTVEVNILYITPDDHMPVG
                     AVQEIYPFSQLVEIPEMSAQAKVELDASLEQLSAVMLDQEHVEIRAAVRLDLIAFVQEV
                     IQNIEEATESEPDLEMLRNRPGLVGYIAKAGDDLWTIARENHTTIQNIMETNHRKSEVL
                     LAGEKVLIVKQVG"
     CDS             complement(2781..3023)
                     /locus_tag="ctg11_51"
                     /transl_table=11
                     /translation="MQQADIRKVRASVHQQCGKKVMIQLDRGRNKVDIQEGVIQNAYPS
                     VFTILVNDEREENPPQLLSFSYSDIITRDIRMKLC"
     CDS             complement(3169..3540)
                     /locus_tag="ctg11_52"
                     /transl_table=11
                     /translation="MAGLISGCSIEQTNETKVSDLTYTIVEESETPEELKTMIEEKKTA
                     DFKLTYEMADDLYIVRGYGEQATGGYSICVRDCYLTTNAVVFDTELIGPRKGEVTNASP
                     SCPYIVIQVKNQDKSIIFE"
     CDS             3736..4470
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg11_53"
                     /sec_met_domain="Acyltransferase (E-value: 3.4e-29,
                     bitscore: 93.2, seeds: 46, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRAILALLFAILYLIIGIPVLFVEWIIGKFNRQAADISQLRMVQ
                     WAFRVILFICGTRLTIIGEENVPKDQPVLYIGNHRSYFDIIITYSRCPRLTGYVAKDSM
                     KKVPLLSVWMTRLHCLFINRSDVKEALKTILAGIDNIKNGISMCIFPEGTRNKTEDLML
                     PFKEGSFKMAEKTGCLIVPMAISGSADILEAHFPKVKPVHVIVEYGKPIDPKSLDKDTR
                     KKLGSHCQGVIAEMLEKNNPQI"
     CDS             complement(4698..6110)
                     /locus_tag="ctg11_54"
                     /transl_table=11
                     /translation="MKNMTLERITEVCGGVYYGSEADKKKEIAGAVIDSRQVESGYLFI
                     AVKGEKVDGHQFIPQVFEKGALAVLSEQELSDPAGPYIRVESTLGAMKKLAAYYRRSLD
                     IKVVGITGSVGKTSTKEMIASVLSQKYNVLKTEGNFNNEIGLPLTIFKIREQHEVAVLE
                     MGISEFGEMHRLAEMAYPDICVITNIGLCHLENLLTRDGILKAKTESFEHLTPEGTAVL
                     NGDDDKLCEKKMVNGKPVVFYGIGKEAKPAKTEQGEKYLAEKEVYATDVEPVGLDGTKA
                     VIHIGAESFAVTIPIAGEHNVYNALAAVCVAGKLGLSVDEMKRGIESVKTIGGRSNLIH
                     KGGMTIIDDCYNANPVSMKASIDVLAAAPGRKIAVLGDMGELGENEQELHAMVGEHFEG
                     KGIDALFAAGALSENLAQAVRKCSKETKVHYFKTKDELMEELLPYVKSGDTVLVKASHF
                     MGFPEVVGQLTK"
     CDS             complement(6166..7221)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg11_55"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 6.4e-54,
                     bitscore: 174.6, seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_N (E-value: 2.3e-26,
                     bitscore: 84.3, seeds: 635, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIVVLAGGLSTERDVSFKTGDMVAKALRENGHQVILLDVFMGYS
                     DKKEDLTGIFDRSEEVSVKVSGIPETAPDLAKVKASRKDQSDNFFGPNVIELCQMSDIV
                     FMALHGENGENGKIQAAFDLFGIRYTGTGYLSSALAMDKEMSKKLFLSAGIPAPKGASM
                     KKADCSDDITKLGIQFPCVVKPCCGGSSIGVSIAHNAEEYKAALDEAFRWEENLIVEEY
                     VKGREFSVGVIEGKALPIIEIAPVQGFYDYKNKYKAGSAVETCPAELSEAVTEKMQHYA
                     EQVAQVLGLDTYSRTDFLLDEKENIYCLEANTLPGMTPTSLLPQEAQVVGVNFNELCEK
                     LIQISLDKYEK"
     CDS             complement(7470..7736)
                     /locus_tag="ctg11_56"
                     /transl_table=11
                     /translation="MYNGAEILVDLARRYPELWNEIDRQCTLNRERYGLLCEILLAGDE
                     ERCEDVVAKIYRYGSMIGKQDLIGRQIFLWLLQALRMEEIAML"
     CDS             7959..8807
                     /locus_tag="ctg11_57"
                     /transl_table=11
                     /translation="MSVRIIVDSASDLTKERADALNLDYMPLKTIFGETEYLDGVTISH
                     KEFYEKLIECGTIPTTSQVSPHDFEAKFKEVKEAGDTAVVICLSSLLSGTYQSAHIALD
                     GYEDCITLVDSLNVCLGEQILVLYAVKLRDEGLSAKEIAEKLEEKKKDVCVLAVFDTLE
                     YLKQGGRISKTAAWAGNILSIKPVIAIEKGEVAILGKARGSKNGNNILIQEVKNKNGID
                     FSMPYMLGYSGLDDSLLRKYIADSADLWVGQTKELPISTIGSTIGTHAGPGAICVSFFH
                     K"
     CDS             complement(9255..9785)
                     /locus_tag="ctg11_58"
                     /transl_table=11
                     /translation="MRIKITGRNIELTDGIKDAVEDKLNKLEKYFTPDTDVYVTLSVEK
                     ERQKVEVTIPMKGNYIRSEQVSNDMYVSIDLVEEVIERQLKKYRTKLVTKQQSAASVFK
                     QDFLDAASDDDEEIKIIRSKKFDMKPMYPEDACVQMELLGHDFFVFINAETEDVNVVYK
                     RKGNTYGLIEPEY"
     CDS             complement(9861..10001)
                     /locus_tag="ctg11_59"
                     /transl_table=11
                     /translation="MASHYDIASLVKCVILIVPANDAHFYKNITGKYKYSEKYIKNDIL
                     Y"
     CDS             complement(10001..10750)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 80.6;
                     E-value: 4.4e-25)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_60"
                     /sec_met_domain="Radical_SAM (E-value: 1.2e-32, bitscore:
                     105.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGYIHSLESFGTVDGPGVRFVVFFEGCPMRCQYCHNPDTWVLTDG
                     KQMEADEIIDRFLRNASFYRTGGITATGGEPMLQIDFLTELFAKAKAHGIHTCLDTSGI
                     MFPGFPEDGEATSDITLEKIDRLLDVTDLVMLDIKHIRDEDHRKLTGHSNKNILAFARY
                     LDQKKKPVWIRHVVVPGITFEEAELTELGHFLKTLSNMEKLEVLPYHALGKVKYDNLGM
                     DYVLKDTPQLTKEEAKKAEQMIRDAMS"
     CDS             complement(10767..12995)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_61"
                     /sec_met_domain="Gly_radical (E-value: 8.5e-46, bitscore:
                     147.0, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 1.1e-280, bitscore:
                     924.2, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQNEWRDFNGGAWENEVNVRDFIQRNYKPYDGDSSFLEGPTEDTT
                     ALWQDVLELSKQEREAGGVLDMDTKIISTITSHGPAYLDKDKEKIVGFQTDKPFKRSLQ
                     PYGGIRMAIKACEDNGYKVDPEVVEYFTTHRKTHNAGVFDAYTPEMRACRSAHIITGLP
                     DAYGRGRIIGDYRRPALYGVDRLIADKEEQLESTRTIMYSDVIREREELSEQIRALKML
                     KELAKIYGCDISKPATNVLEAAQAVYFAYLAAVKEQNGAAMSLGRTSTFLDIYAERDLR
                     EGTFTEKEIQEIIDQFVMKLRCVKFARTPEYNSIFAGDPTWVTESIAGIGVDGRHMVTK
                     MSYRYLNTLNNIGAAPEPNMTVLWSVKLPENFKKFCAEISIKHSAIQYENDDIMRVVHG
                     DDYGIACCVSSMRIGKEMQFFGARANLAKCLLYAINGGVDEISGKQVGPKYRPITSEYL
                     DYDEVWEKYKDMMKWLAGVYVNALNIIHYMHDKYCYEKLQMALHDKQVRRWFATGIAGF
                     SVVADSLSAIKYAKVKPIRDENGITVDFEVEGDFPKYGNDDDRVDEIAKEVLHTFIKYV
                     KGNHTYRGGIATTSILTITSNVSYGKNTGATPDGRKKGVAFAPGANPMHGRDKNGAVAS
                     LASVAKMPFMDAQDGISNTFTIVPDALGKTEESSETNLVALLDGYAEKGGHHLNVNVLN
                     KETLLDAQKHPEEYPQLTIRVSGYAVNFIKLTKEQQDEVIARTFHELM"
     CDS             complement(13386..14318)
                     /locus_tag="ctg11_62"
                     /transl_table=11
                     /translation="MESSVLEEKVFHKVMKNVPFGLVVSSEGRKRKVYYVNTMAYHMLG
                     YTREEFIEKVQDGWSRFVDIDLRTVMREHHEEILTGESFELTAQTETKDGNKKWLSFRV
                     MVSMDVISSQLKPVSYITITDVTEKVEKNRRYAREREYLRDCAARDSMTRLLNRGTMED
                     RIKEELESVAEGQNYAYIAIDLDNFKQVNDVYGHWVGDRVIMSVSNILREVYGNQVSIG
                     RMGGDEFAVFLPDVKDRMWIQGQADEVLYRLRRQKEMIGMAEEPTASIGIAFGPEDGTS
                     FRELYHRADAALYQVKKEEKNSIAIYTMI"
ORIGIN
        1 ctcacaccgg tagagtagga tggatttaaa ccgttatttg tcagtcctgt cgaactgctg
       61 ccggaagaac tgctgtcgga atcgtccgtt gaagctgtat tattggaaga ggaacttccc
      121 cctgtactgt ctgttgttcc gctgtccgta gatgccgttg tggcagaatt actggttttt
      181 gtgcctacct tcgccgcttt ctttgccttc tcttctgctt ctttccgggc tttttcctga
      241 cgcgcctgtt cctgtgcgat cacctcgttc tgtttgcgga tcgtggacgc gtactggctt
      301 gccagtgttt ttgcatttga aagctgtgaa tcaaaatctg caatctgtgc cttcttttca
      361 ttaataacct gattcaggga agcctcctgc tgatcataac tttgtttcag ctcctccata
      421 tccgctaatt cctgctctaa ctgtgactct aaatccgcca cctgctgtac ggtctcctga
      481 taagccacta aaagctccct gtcataactg tatacttccg atacatactc cacacgattt
      541 aaaaggtctg agatatcttc cgactccaca agtgcatcca gaaatgtgtc atctccgttt
      601 tcgtacatgt actggattct ttttttcata tctgcatact gctgctgttc tttttcctgt
      661 gctgcggcga gatccgtctt tgcctgatca atctcgcctt ccttattatc aatatccgtt
      721 ttcaacagtt ccatatcggt caaaagcgac atcagctgtt catcatacgc cgccatctgg
      781 ctttttacct tgctctgctc actctgtata ttattgatct gctggttgat attgtctaaa
      841 ttctgctgcg cctcattttt cttcttcttc gcatctttta tcacagatgc atctgcagag
      901 taaaaacacg caaatccgat cacacctgcc atcatcactg cgatcattct tttatgtttt
      961 cttgtatatt ttaatgcctt ttcccacatc atcaagcatt tctccttctg tcatttataa
     1021 aagaatagga cataatttcc tacgaatcaa aaataagcac ggcaggctgc agtgggcaga
     1081 agccgtactt atatatttta tcacactttc atctatgttt gttaggattt ccagaaattc
     1141 acaaatactt aatattttat ccgacctgtt ttacgatcaa aaccttttcg cccgccagaa
     1201 gtacctcact ttttctgtga tttgtctcca tgatattttg tatggtcgta tgattttccc
     1261 tggcgatcgt ccagagatca tctcctgcct ttgcgatata gcccaccagc cccggcctgt
     1321 tcctgagcat ctcaagatcc ggttccgact ctgtggcctc ctcgatattc tgtatgactt
     1381 cctgcacaaa ggcaatcaga tccagccgta ctgccgcccg gatctcaacg tgttcctgat
     1441 caagcatcac cgctgagagc tgctctaagg aagcatctaa ctccactttc gcctgcgctg
     1501 acatttccgg gatctccaca agctgtgaaa acggataaat ttcctgcact gctccaaccg
     1561 gcatatggtc atccggtgta atgtacaaaa tattgacctc aaccgttccc tccgcaagaa
     1621 caccatctgg ttttatttcc tgacgttcta agagcacttt tccctcacag gaacagatct
     1681 gaagaacttt ttctttatct tcttttaatt ccatctgttc tgtcattctg cattttgcag
     1741 catttttaac cagaagacgc tccagcgggc attcacggaa gactggtttt acctctttct
     1801 gcagtgaata cagatctgtt aaaagtctta tcttttcttc cttccagata cggatgtgtg
     1861 tatctaatgc cagctccatg acaaggatcc tttcttcccc gtcataatcc ggtttgactt
     1921 ccagttccat tgtcaaaggt accatctgca cctgccagat acagtcatcc tccataacac
     1981 cgcactctgc ctgtgcatcc agcgggactg tcgtttcata ccaggacaga tgctcccctt
     2041 cctcctcatc attatacagt atggaaacca gtatttcccc ggaaagtctg atatttcctt
     2101 ccacaagcct gctttcaaca ttgcgcagct gcatactctg ccagagtatt tcacggatat
     2161 tcggtttact cgacggcagc actgcctcac ttttctgtct gcagatatca cgtcgcacca
     2221 caagcagctt taacgcttcc ttctctacaa tattctgttc ataggaactg ccatctgaga
     2281 gttcacaggt cagctcctca tccacttctt tttctgacga tgccgtcaaa acaatgaccg
     2341 cgcggacatt taacttccgg gaattgatca ctccgatcgt aagatcttcc atatcccctg
     2401 tggcatgaac tgcatcatat tcgctcagac catccatgtt aagccgttcc tgaaaaggaa
     2461 tctcaccgcg cagacagctt atttttcctt cctgcttatc gctccggtaa agtaccttaa
     2521 aaagcagact gcccttgatc catgcagccc cctccatcgc ttttacttca tcaaagcgca
     2581 gttccccgcg ttcttttatg acttttacga tatcctgtct gtaatccggt acattatagt
     2641 catcatccag tgtgatctgt gtgactgcag ctctgttttt ttcacttcta tgtaatttta
     2701 ttttctgaaa ttccaaaaaa agtcccccat tccgaatctt tgtaaccatc ttattcggac
     2761 atggaggatt ttatacctgt ttagcacaac ttcatgcgta tatctcttgt aataatatca
     2821 gaataactga atgataataa ctgaggtgga ttttcttcac gctcatcatt taccaggatc
     2881 gtgaatacgc ttgggtaagc attctggatg acgccttcct ggatgtcaac tttattgcgt
     2941 cctcggtcaa gctgaatcat tacttttttc ccgcactgct gatgcacgga tgcccgaact
     3001 tttctgatgt ctgcctgttg catgtgttct acctccttaa tccggcatct cgcgatcgtt
     3061 tatcatcgta atgatcgttt ccaccgaatt tcttttccgc tttagaatag cactgtgcta
     3121 aatttttgtc aaacataatt aaattattta aaaaaatttt aagaatattt actcaaaaat
     3181 gatacttttg tcctggtttt ttacctgtat tacaatataa ggacagcttg gactcgcatt
     3241 tgtaacttca ccctttctcg gtccgatgag ttctgtatca aacactactg cgtttgtggt
     3301 cagataacag tccctcacac agatactgta tcctcccgtc gcctgctccc catatccccg
     3361 cacgatatac agatcatccg ccatctcata ggtaagttta aaatccgccg ttttcttttc
     3421 ctcgatcatt gtctttaact cttccggtgt ctcggattcc tcaacgatcg tatatgtaag
     3481 atcactgact tttgtttcat ttgtctgctc aatactgcat ccgctgatca gtcctgccat
     3541 cagcagactg atcccgcata tttttaccag atactttcga aacatgcttt cactacacct
     3601 gcccccagtt ttcgcttcta tcttaatgta tgcctccctg tctttaaata tgtctttttt
     3661 agttgttttt cccatagata cccgatataa tgtgggtata taaaacttgg gggatctccc
     3721 cggaaaggac gtactatgtt acgcgcaata cttgcattgc tttttgctat actctatctg
     3781 atcatcggta ttcctgtcct ttttgttgaa tggatcatcg gaaaattcaa tcgtcaggct
     3841 gctgatatca gccagctccg catggtgcag tgggcatttc gtgtcattct gtttatctgt
     3901 ggcaccagac ttaccattat cggagaagaa aatgttccaa aagaccagcc tgttctctat
     3961 attggcaatc acaggagtta tttcgatatc atcatcacct actcacgctg tccgcgcctg
     4021 accggttatg tagcaaaaga ttccatgaaa aaggttcctc ttttatctgt ctggatgacc
     4081 agactgcact gtctgttcat caatcgttcg gatgtcaaag aagcgctaaa aacgatcctt
     4141 gcaggaatcg acaatatcaa aaacgggatt tcgatgtgta ttttccctga gggaacacgc
     4201 aataagacag aggatctgat gctcccattc aaagagggta gttttaaaat ggcagaaaaa
     4261 accggatgtc tgatcgtacc tatggcaatt tccggctccg ccgatatttt agaagctcat
     4321 tttccaaagg taaaaccggt acatgtcatc gtagaatacg gcaaaccaat tgacccgaaa
     4381 tctttagaca aagatacacg caaaaaactc ggttcacact gtcagggtgt gatcgctgaa
     4441 atgcttgaga aaaataatcc gcagatttaa gatctggaac aaagagtcgc ttgcgattct
     4501 ttcgcgctcg agcggtgctg tttacagcta acttctactc cgcgagatgc gcatcccgcc
     4561 cggaggactt tttaattcat aggacgtaat ttcctatgaa tttaaaaaaa tccccggatc
     4621 accaattccg tgatccgggg attttctttt ttattcattt ataagctgtc atagcttcgt
     4681 attttcacta cattttctta ctttgtaagc tgtcctacga cctccgggaa tcccataaag
     4741 tgggatgcct ttaccaaaac cgtgtcaccg ctttttacat aaggcagtaa ttcttccatc
     4801 agttcatctt ttgttttgaa ataatgaacc ttcgtctcct tactgcattt tcttactgcc
     4861 tgtgccagat tctctgataa tgcaccggct gcaaacaaag catcgattcc ttttccttcg
     4921 aaatgttctc cgaccatggc atgcagttcc tgctcatttt cgccaagttc tcccatatct
     4981 ccaagcactg cgatttttct tccaggtgcc gctgcgagca cgtcgatgga cgccttcatg
     5041 gaaacagggt ttgcgttgta acagtcatcg atgatcgtca tcccgccttt gtggatcaga
     5101 ttacttcttc ctccgatcgt ttttaccgac tcaatcccgc gtttcatttc atccacacta
     5161 agtccaagct ttcctgcaac gcagactgcg gctaaagcat tgtatacatt atgctctcct
     5221 gcaatcggga tcgtcactgc aaagctctct gcaccaatat gtatcaccgc ttttgttcca
     5281 tctaatccta ccggttccac atctgttgca tatacttcct tttcggcaag atatttttca
     5341 ccctgctctg tctttgcagg cttcgcttct tttccgatac cataaaatac caccggtttt
     5401 ccgttcacca tctttttctc acagagctta tcatcatctc catttaacac ggcagttcct
     5461 tccggtgtca gatgctcaaa actctccgtt tttgccttta aaattccatc tctggtcagc
     5521 agattttcca gatggcacaa tccgatattt gtgatcacac agatatccgg atatgccatt
     5581 tcagccagac ggtgcatctc accgaattct gaaattccca tctcaagcac tgccacttca
     5641 tgctgctccc tgatcttaaa aatcgtaagt ggaagaccga tctcgttatt gaaattgccc
     5701 tctgtcttta acacattata cttctgtgaa agaaccgatg cgatcatctc ttttgtgctt
     5761 gtttttccaa cacttccggt aattccgacg accttaatat caagacttct gcggtagtat
     5821 gctgcaagtt ttttcattgc accaagtgtt gattccaccc tgatatatgg tcccgccgga
     5881 tctgacagtt cctgttcgga taatacggca agtgcacctt tttcaaacac ctgcggaatg
     5941 aactgatgac catccacctt ttctcccttt accgcaataa aaagatatcc tgactctacc
     6001 tgtctgctgt cgatcacagc tcctgcaatt tctttctttt tgtcggcctc actgccataa
     6061 tatactccac cgcatacttc cgtaatacgc tccagtgtca tgtttttcat gatctacctc
     6121 atttcccggg attcgttttg cttttacttt tacaaaaata tcttattatt tctcatattt
     6181 atccagggaa atctggatca gtttctcaca cagttcgtta aagttcacac cgacaacctg
     6241 tgcctcctgt gggagaaggc ttgtcggagt catgcccggc agtgtattcg cctctaaaca
     6301 gtagatgttt tccttctcat ctaacaggaa atccgtgcgg gagtaagtat caagtccaag
     6361 tacctgtgct acctgctctg catagtgctg cattttctct gtgacagctt ctgaaagttc
     6421 tgccggacag gtctcaacag cactgcctgc tttgtatttg ttcttataat cataaaatcc
     6481 ctgtaccggt gcgatctcga tgatcggaag tgcttttccc tcgatcacgc cgacagagaa
     6541 ctcacgtcct tttacatatt cttccacgat caggttttct tcccagcgga acgcctcatc
     6601 taatgctgct ttatattcct ccgcattgtg tgcgatggaa acaccgatac tcgaacctcc
     6661 gcagcatggt tttaccacac acgggaactg aatgccaagt tttgtgatat cgtcgctgca
     6721 gtcagccttt ttcatggatg cgccctttgg agccggtatg cctgctgaca aaaataattt
     6781 tttggacatc tccttatcca tggcaagcgc actgcttaaa taaccggttc ctgtatagcg
     6841 gatgccaaac agatcaaatg cggcctgaat cttgccgttt tctccgtttt ctccatgcag
     6901 tgccataaaa acgatatcgg acatctggca taattcgatc acattcggtc caaagaaatt
     6961 gtctgactga tcttttctgg acgcttttac ctttgcaaga tccggtgcag tttccggtat
     7021 tccggatact tttacactga cttcctcact ccggtcaaaa atacctgtca gatcttcttt
     7081 tttatcactg tatcccataa atacatcaag caaaattacc tgatgtccat tctctctcaa
     7141 tgcctttgcc accatatctc cggtcttaaa ggaaacatct ctctctgtac ttaaaccacc
     7201 tgctaaaaca acaatcttca tggtatactc tccttactat ctcataaaaa catttctgct
     7261 ttatagtata ccttttttct ttgtgtggca aggaatttgc acattccttt gtacttttta
     7321 tgcctgcatg acatcctttc ttatttattt ttctgcctca cggcaggcac cattttttct
     7381 tttattcccc gttttcccgt accggaaaag attcctgact cataaaattc tttgcctgct
     7441 gctggcctct ttcacgataa aacccatttc tacagcattg cgatttcttc catcctcagt
     7501 gcctgcagca gccacaaaaa tatctgtctt ccaatcagat cctgttttcc gatcatactc
     7561 ccgtaccggt atatctttgc aaccacatcc tcacagcgtt cctcgtcccc cgccagcaat
     7621 atttcacaga gcaatccgta ccgctctctg tttaaagtgc actgcctgtc tatttcattc
     7681 catagttccg gataccttct tgcgagatcc accagaatct ctgccccgtt atacatttct
     7741 tccgctttct tctgctctgt tatataattt tccactttta cactactgtc atgcaggcat
     7801 tgatactaca caagtatctt atgtctgtcg atttttgtca actacatttg atttttgttt
     7861 taatactttg ataatcaaaa tatcttgaca ttcttttcat catactttat atttattttt
     7921 gtttgatagt caaactattt tatccggagg gaaaaaaaat gagtgtacga attattgttg
     7981 attccgcatc tgatctcaca aaggaacgtg cggatgcttt aaatcttgat tatatgcctt
     8041 taaaaacaat ttttggcgaa acggaatatt tagacggtgt taccatttcc cataaagaat
     8101 tttatgaaaa actgatcgaa tgtggaacaa tcccgacgac cagccaggta tctccacatg
     8161 attttgaagc gaaattcaaa gaagtaaaag aagccggcga taccgccgtt gtgatctgtc
     8221 tgtcctctct tttatccggt acataccaga gtgcacacat tgcgcttgat ggctatgagg
     8281 actgtatcac attagttgac agtttaaatg tatgtctggg cgaacagatc cttgtccttt
     8341 atgccgtaaa gctgcgcgat gaggggcttt ctgcgaaaga gatcgccgaa aaactcgaag
     8401 agaaaaagaa agatgtctgt gtcttagctg tctttgatac ccttgagtat ttaaaacagg
     8461 gcggacgcat ctcaaagact gccgcctggg cgggaaatat tttatccatc aagcctgtca
     8521 tcgccattga aaaaggtgag gttgcgatct taggaaaggc cagaggatcg aaaaacggaa
     8581 ataacatcct gatccaggaa gtgaaaaata aaaacggtat cgatttttcc atgccgtata
     8641 tgttaggcta cagcgggctc gacgactcac tgctccggaa gtatattgcg gacagcgcag
     8701 atctctgggt cggacagaca aaagagctgc caatcagcac gattgggagt acgatcggta
     8761 cacatgcggg accgggagcc atctgtgtgt cgtttttcca taaataataa tgatgttgga
     8821 acaaatattg atttcaaatt tcttgattga caaattgcaa caatccgggt ctgttttgtt
     8881 ccattgtacg aaaataagga aatctaagtc tgcctgatta gattttctca aagtgacgtg
     8941 aacggcgttc aacgagcctt ccatggctcg tgaagccttg ttctgccatc cgtggcagaa
     9001 catcactgtg aatagacagg caggctaaga ttttctaatt ttcttccaaa gtcacaaaag
     9061 tattcccggc ttgttgcaat ttgtcagtcg ttatgttgtg aatcactatt tgccccaaca
     9121 tcttatcttc gacaaatgct tcacgtcaca caaggaaatc tattatgatg tactgcaaaa
     9181 acccaccctg cggcaaggtg cttgccgcag ggtgggttct ttgtattcac agcacaattc
     9241 tgcaatgatc cattttagta ttccggttcg atcaatccgt atgtgttgcc ttttctcttg
     9301 tatacaacgt tgacatcttc ggtctcagca ttgataaata cgaagaagtc atgtcctaat
     9361 aactccatct gtacacatgc atcttccgga tacatcggct tcatatcgaa cttcttagaa
     9421 cggatgatct tgatctcttc atcatcgtct gatgctgcat ccaggaaatc ctgtttgaaa
     9481 acggatgctg cgctctgctg tttcgtaacc agtttcgttc tatatttctt taactgacgc
     9541 tcaataacct cttctaccag atcaattgat acatacatat cattgctgac ctgttcagaa
     9601 cgaatatagt ttcctttcat tggaatcgta acttccactt tctggcgttc cttctctacg
     9661 ctcagtgtta catagacatc tgtgtccgga gtgaagtatt tctctaattt gtttaacttg
     9721 tcctccactg catctttgat accatcggtt aattcaatgt ttcttcctgt aatcttgatt
     9781 ctcatgatgt ccaacccctt tgccgtttat ttgatacaga tttatatcat ggttttatta
     9841 tagcactttc cacaaatatt tcaatacaat atatcatttt ttatatattt ttcagaatat
     9901 ttatattttc ctgtaatatt cttgtaaaaa tgtgcatcat tcgctggcac gatcaatatt
     9961 acacatttaa caagggatgc aatgtcataa tgactcgcca ttatgacatt gcatccctta
    10021 tcatctgttc cgcttttttt gcttcctctt tggtaagctg cggtgtatct tttaacacat
    10081 aatccatgcc aagattatca tacttgacct tgccaagtgc atgatatggc agtacttcca
    10141 atttttccat attggaaagt gtctttagga agtgtccgag ttccgtcaat tctgcctcct
    10201 caaatgtgat gccgggaaca acgacatgac ggatccacac cggctttttc ttctgatcta
    10261 aatatcttgc aaatgccaga atattcttat ttgaatgtcc ggtcagtttc cggtgatcct
    10321 cgtcacggat atgcttaatg tcaagcatta caagatctgt gacatcaaga agcctgtcta
    10381 ttttttccag tgtgatatct gatgtggctt ctccatcctc cggaaatccc gggaacataa
    10441 taccagacgt atctaaacag gtatggattc catgcgcctt tgccttcgca aacagttccg
    10501 tcagaaaatc gatctgaagc atcggctcgc caccggtggc ggtaattcca ccagtccggt
    10561 aaaaagaggc attgcgcagg aagcggtcga tgatctcgtc cgcctccatc tgttttccat
    10621 cagtcagcac ccatgtatcc gggttatggc aatactggca gcgcatcggg cagccctcga
    10681 agaatacgac aaaacgcacc ccaggaccgt ccacggtacc aaatgattcc agagaatgaa
    10741 tatagcccat aataatctcc ttatttttac atcagttcat ggaatgttct tgcaattacc
    10801 tcatcctgct gctctttggt cagtttgatg aagtttactg cgtaacctga tacacggatt
    10861 gtaagctgcg gatattcctc cggatgcttc tgtgcatcaa gcagtgtttc cttatttaat
    10921 acgtttacat ttaagtggtg accgcctttt tctgcatagc cgtcaagcag tgccacaagg
    10981 tttgtttcag agctttcctc cgtctttcca agtgcatccg gcacgatggt aaaggtgttg
    11041 gaaataccat cctgcgcatc cataaatggc atttttgcaa cggaagctaa ggaagcaacc
    11101 gcaccgtttt tatcacgtcc gtgcattgga tttgcacccg gagcaaatgc aacacctttc
    11161 tttcttccat ccggggttgc tcctgtattt ttaccatagg atacattgga tgtaatggta
    11221 agaatggaag ttgttgcgat accaccgcga taggtgtgat ttccttttac atatttgata
    11281 aaggtatgaa gaacctcttt tgcgatttca tccacacggt catcatcatt accatatttc
    11341 ggaaaatctc cctcgacctc aaaatctaca gtaatgccgt tctcatcacg gatcggtttt
    11401 acttttgcat atttgattgc agacagggaa tctgctacta cggagaatcc cgcaataccg
    11461 gttgcaaacc agcgtcttac ctgtttgtca tgcagcgcca tctgcagttt ttcatagcag
    11521 tatttgtcat gcatatagtg aatgatgttt aatgcattga catagacacc tgcaagccat
    11581 ttcatcatgt ctttatattt ctcccacacc tcgtcatagt caaggtactc ggaagtaatc
    11641 ggacgatatt tcggtcctac ctgttttccg ctgatctcat ccacaccacc gttgatcgcg
    11701 taaagtaaac attttgcaag gtttgcacgg gctccgaaga actgcatctc ttttccgatc
    11761 ctcatggaag atacacagca tgcaatgccg tagtcatcac catgaaccac acgcatgata
    11821 tcatcatttt catactggat cgcagaatgt ttgattgaga tctctgcaca gaacttttta
    11881 aagttctccg gaagttttac agaccataaa actgtcatat taggctccgg tgctgctccg
    11941 atgttgttta aagtatttaa ataacggtaa gacatttttg ttaccatatg tcttccatct
    12001 acaccgattc cggcaataga ctctgttacc catgtcggat ctccggcgaa aatactgttg
    12061 tactccggcg tacgggcaaa ttttacacag cgcagtttca ttacgaactg atcgatgatc
    12121 tcctggatct ctttctcagt gaaagttcct tcacgaagat cacgctctgc atagatatct
    12181 aagaatgtag aagtacgtcc aaggctcatt gccgcaccgt tctgctcttt gactgctgca
    12241 aggtaggcaa aataaacagc ctgtgctgcc tcaagaacgt ttgttgccgg ctttgaaatg
    12301 tcacatccgt aaatctttgc taattctttt aacattttaa gagctctgat ctgctcggat
    12361 aattcctcac gctcacggat aacgtcagaa tacataatcg tacgtgtgga ttctaactgt
    12421 tcttccttgt ctgcgatcag acgatccaca ccataaagag ccggtcttct gtaatcgcca
    12481 atgatacgtc cgcgtccgta tgcatccgga agaccggtaa tgatatgtgc agaacggcag
    12541 gctctcatct ccggtgtata cgcatcaaat acgcctgcat tgtgtgtctt tctgtgtgtt
    12601 gtgaaatatt ctaccacttc cgggtctact ttatacccat tatcttcaca tgccttaatt
    12661 gccatacgga taccgccata aggctgtaag gaacgtttga atggtttatc tgtctggaaa
    12721 cctacgatct tctccttatc tttgtctaag tacgcaggtc catgggaagt gatcgtggaa
    12781 atgatctttg tatccatatc gagcacgccg ccggcctctc tctcctgctt tgaaagctct
    12841 aatacgtcct gccagagtgc tgtggtatcc tctgtcggtc cctccaaaaa agagctgtca
    12901 ccatcgtatg gcttataatt tctctgaatg aagtctctga catttacttc attctcccat
    12961 gctccaccat taaaatctct ccattcgttt tgcattattt ttcctcctgt ttgctgaaaa
    13021 ctatggttta cctgtataaa acggatctga tcccccaata ttttggtatt gctggaaaat
    13081 attggtagtc atttctaact tttgttagtt agttctaacg cagtgaatat atcatgtttc
    13141 atcactgctt gtcaatatcc gcttcgtttc cggaactgtt ctttttttca tacaaaagga
    13201 ttcctgtaag aagaatatct ttaagaataa aagaaaccga cagtccgggt tatctcgccc
    13261 agacggtcgg cattgtaaac gttatacttc atgtggttct tccacttttt ccgtcagtca
    13321 tataacaatt agatgttata atttttgatt cattttttca ataggtaaaa tgtaccaaaa
    13381 aaaacttata tcattgtgta aattgctatg ctgttttttt cttccttttt gacctgatag
    13441 agtgctgcat ccgctctgtg atacagttca cggaagcttg tgccatcctc agggccgaat
    13501 gcgatgccaa tacttgctgt cggctcctcc gccattccga tcatttcttt ttgtctgcgc
    13561 agccggtaca gcacttcatc tgcctgcccc tgtatccaca tacggtcttt tacatccgga
    13621 agaaatactg cgaattcatc cccgcccata cgtccaatgc tgacctgatt accgtagact
    13681 tcccttaaaa tattagacac actcataatg acgcggtcgc caacccagtg gccatacaca
    13741 tcattgacct gcttaaaatt atccagatca atagcaatgt atgcgtaatt ttgtccttct
    13801 gccactgact ccagttcttc tttgatacga tcttccatcg taccacggtt taacagtctc
    13861 gtcatggaat ctctggctgc acaatcccgt aaatattctc tttctctcgc gtaacgtctg
    13921 tttttttcca ctttctccgt tacatctgtg atcgtaatat aactgaccgg ttttaactgc
    13981 gaggatataa catccatgga taccatcaca cgaaaagaca gccacttttt atttccgtct
    14041 ttcgtctctg tctgagcagt cagctcaaat gactcccctg tcagaatctc ttcatgatgc
    14101 tccctcatga ccgttcttaa gtcaatatcc acaaaccggc tccagccgtc ctgtactttt
    14161 tcaataaatt cctcccgcgt gtaaccgagc atatggtacg ccatcgtatt cacataatac
    14221 accttgcgtt ttctgccctc actgctcaca acaagaccaa acggtacgtt tttcataact
    14281 ttatgaaaaa ccttttcctc caataccgag ctttccattc tccctctccc gttaaaaaat
    14341 taactaattg atcccccaaa cagtatacta cattacttta aaataaaaaa gtatttttat
    14401 gaatattttt ctttcttcta gacttccata cttttttcct atataattta tctaactaaa
    14461 acttcccaca ccatattggt gtgttgatcc ttgaaaa
//
