LOCUS       c00027_gnlPro..        14609 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IIJCMEKJ_27.
ACCESSION   c00027_gnlPro..
VERSION     c00027_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 20:19:13
            Original ID  :: gnl|Prokka|IIJCMEKJ_27
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14609
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1089)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_2"
                     /gene_functions="transport (smcogs) SMCOG1005:MFS sugar
                     transport protein (Score: 197.9; E-value: 7.4e-61)"
                     /gene_kind="transport"
                     /locus_tag="ctg27_1"
                     /sec_met_domain="MFS_2 (E-value: 3e-61, bitscore: 197.9,
                     seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNRKKVPLKNKLAYGIGTGGGNVFSQIAAAFLLNYYTDTALIGA
                     GAIATMFLVCRVFDGITDLLMGGIVDKTSTKLGKARPWLIASAPLSLLGIVLLMNVPMG
                     LGENGKLVYAYITYIFMSCIVYTIYGISNTALLPLMTHDKDDSTMLATFSALGNNIIGL
                     IAGSLITPLVLNLGWKTSSIILGFAACVLILISGLLNKEMVNDEDTKKMAGIPMSQQLP
                     ATLKNKYFWLLLLLGAFSLIMNANAIGAQIYYCNMVLGNPMFMSVLMTAGQLPGIFILF
                     FMPAVSKKWNKKTFLLMGAVLIIVGFIITGIAGGNTTLIVIGTVIRSLGVGPILSAVFA
                     LVPDVVQYGLSTLFQTNFFRLFF"
     protocluster    1..14609
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2580:4609]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Flavoprotein,
                     Semialdhyde_dh]) and gallic_acid)"
                     /neighbourhood="10000"
                     /product="gallic_acid_met"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2581..4609
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Flavoprotein,
                     Semialdhyde_dh]) and gallic_acid)"
                     /neighbourhood="10000"
                     /product="gallic_acid_met"
                     /protocluster_number="1"
     cand_cluster    1..14609
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [Flavoprotein,
                     Semialdhyde_dh]) and gallic_acid)"
                     /kind="single"
                     /product="gallic_acid_met"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14609
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="gallic_acid_met"
                     /region_number="1"
                     /rules="(minimum(1, [Flavoprotein, Semialdhyde_dh]) and
                     gallic_acid)"
                     /tool="gutsmash"
     CDS             1208..2134
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     63.9; E-value: 3.2e-20)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg27_2"
                     /sec_met_domain="LysR_substrate (E-value: 5.4e-31,
                     bitscore: 98.3, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.3e-20, bitscore: 63.9,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTENLKEFIVLAETKNFWEASERLYMNQSTLSKHIKSLENDLGV
                     ALFTRTTRRVELTNYGEIFLPYAKSVTRSEFEGISAIQRMLNIENGLLTIGTIPSMPQY
                     HITQFLAQFQKLYPETTVRITEDDPVNLMTYLENEKCELIFNREDKVTFEKNFLNDHHI
                     LRIPYMSDHLVALIPLSHPLASSSSITLQQLKNDRFCFIKEGSLMYQMSMDACQNAGFI
                     PDIVFTSHRIDSILDMVTNQNCVALLMNVHLQLPENGPKQTGAPWCAVPITPVISSQLS
                     LCYRCDKPLSKTAQLFVNLCNDKLFKS"
     CDS             complement(2206..2550)
                     /locus_tag="ctg27_3"
                     /transl_table=11
                     /translation="LINLIEKQIVLLDRIVQVSVCRTECGIQVLIAGGDRSHIGAVSIV
                     DEKSNLISHVFEGHKDHVISDRWAVKLYERFLVPVVVSAGIHYDKITPDGIKTVIEEIE
                     KLLEEVMAYE"
     CDS             complement(2581..3141)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     gallic_acid_met: Flavoprotein"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg27_4"
                     /sec_met_domain="Flavoprotein (E-value: 1.9e-26, bitscore:
                     83.4, seeds: 91, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKILVGISGASGAPIAIRLLKRLREMADVETHLIMTKGAELTIV
                     QETDCTVEQVKALADVVYDVSSLGECPASGSFKMDAMIIVPCSMKTAAGIASGYSDNLL
                     LRAADVTLKEARQLVLVARESPLSPVHLRNLHELSSMGVRVVPPMISFYQKYTTIEAWT
                     DNFAERLLEILGLHNTMQSWSGM"
     CDS             complement(3143..4609)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     gallic_acid_met: gallic_acid"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg27_5"
                     /sec_met_domain="gallic_acid (E-value: 2.6e-228, bitscore:
                     748.4, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVVNDLRSALEVLRQMDGQLVETDIEVDPEAELAGVYRHVGAGGT
                     VMRPTKIDGPAMIFNNIKNHKDARVVIGLLASRERVARLMGCKKEELGKLLCRAALNPI
                     EPVVSEEKAPCQEVIHKVTDPDFDLFKLFPAPTNTPMDAGPYITMGMCYATHPDTGCSD
                     VTIHRMCIQSKDELSIFLQPGSRHIGVMAERATELGQPLPISISIGVDPAIEVGSCFEP
                     PTTPLGYNELSIAGAIRKTPVVLAPCVSIKENAIANAEYVIEGEIQPGIRVVEDQNTHT
                     GYAMPEFPGYNGLASHECWLIKVKAVTHRKNPIMQTVIGPSEEHVNLAGIPTEASIYNM
                     LEKALPGKVTNVYAHQSGGGKYMAVLQCRKTVHTDEGKQRQAALLAFSAFPELKHVILV
                     DEDVDIFDTRDVLWAMNTRFQGDRDIITIPGVRCHPLDPSSDPVYSQSISDKGISCKTI
                     FDCTVPFELKDKFARAKFMDIDEEKWKDFI"
     CDS             complement(4841..4966)
                     /locus_tag="ctg27_6"
                     /transl_table=11
                     /translation="MADQTLPLNVSDEMKSDDERQNCVGMENDEELCSSSATDKL"
     CDS             complement(4983..5174)
                     /locus_tag="ctg27_7"
                     /transl_table=11
                     /translation="MEWYQMDAGKCLEFSKKMAVLRKLVRLGLISENEYIRAKNRIMSS
                     YHILESEYFKSGTGKRVA"
     CDS             complement(5619..6431)
                     /locus_tag="ctg27_8"
                     /transl_table=11
                     /translation="MSLRISAEDKEQIEEKERKNGLTTSEYIRRCALGRKLPCYGDTSL
                     LKEYSMQLGKIGSNLNQIAKHLNSGGSYFSVYSDVKEAVKELLDLKFKILPALEDVACG
                     KKHRRMGYTEEKIKSIRYKMSLYDEFMEEYNCRKRNSNKIEKSKEISYRKDRGGKYLHK
                     LSPVRIINRGRNDNGKWCYIFPAIDIFPADFVIAFFSFTVVIQMIPLPNHFLKIRNTSC
                     RIFHSLQSNGLYITFQKSSVRMLIFTEVRQFLLFCMVYLSVIPALYIK"
     CDS             complement(6473..6841)
                     /locus_tag="ctg27_9"
                     /transl_table=11
                     /translation="MRDLEKVCIQPKYNYCTGEERFTFIKLPKCLVEDEGFVELSMDAK
                     LLYALFLDRVSLSIKNGWIDNQGRVFIYYSIKNICVDLNCGTQKACKLLDELEKVGALE
                     RKRQGLGRPNKLYLKKMF"
     CDS             complement(6987..7343)
                     /locus_tag="ctg27_10"
                     /transl_table=11
                     /translation="VKEYSKGIYVKFKPEEVEILHNRMKEAGVQNMSAYIRKMALNGYV
                     IIPKWPDLDQVISLHSRISNNLNQYARKANETGKLYEEDIAEIEKMHNEQTKFLKKTLE
                     AVMYLYEEDSKKKK"
     CDS             complement(7782..8549)
                     /locus_tag="ctg27_11"
                     /transl_table=11
                     /translation="VKKIVQTAGRNALNEFAPQFAHFNDDVLFGENWNNQDIDVKTRCI
                     ITVTALIASGMINTSLVHHFENAKAHGVTQKEIAAVITHIAFYAGWPKGWAAFNLAKDV
                     WSIDEGDLSYEDEAMRAHAKKMIFPIGEPNDKFAQYFTGKSFLAPVSTSQVGIFNVTFE
                     PSCRNNWHIHHAKSGGGQILICIAGRGYYQEEGKEAVEMKPGDCVNIPAEVKHWHGAAP
                     DEWFSHLAIEVPGEKTSSKWCETVTDEIYEKLK"
     CDS             complement(8565..9119)
                     /locus_tag="ctg27_12"
                     /transl_table=11
                     /translation="MRKNFGAKPFLYPQPVMILGTYDENGKANAMNAAWGGIVGANEII
                     VDLSAHKTTDNIIKNKAFTVGVADLEHLVACDYVGIVSANKEADKMKKAGFTTTKGEFV
                     NAPIINELPLTLECELVKVIDGSKYLAEIKNVSADEKYLGDDGEIDLSKFTPITYDPVH
                     HGYYRLGERVGNAFKDGAKLK"
     CDS             complement(9140..9385)
                     /locus_tag="ctg27_13"
                     /transl_table=11
                     /translation="MAPAVLTFLTTNDFTGKTVIPFMTNGGWPGHVIKDMEENCKGAAF
                     AHEMQIQFDSKGKDHLETSEEVITEWIGQINTDINK"
     CDS             complement(9587..11167)
                     /locus_tag="ctg27_14"
                     /transl_table=11
                     /translation="MAEKRKLAFYIRLSDADEEVKAGTKDESNSITGQRKLLYAYIKKT
                     EEFAGFEVLEYFDDGYSGTMFNNRAEFQRLIQDAELGRFECIIVKDFSRFGRDYLEVGN
                     YLEFVFPAMGMRFISVNDNYDSDRNFGVTGGMDVAYKNLIYQLYSMDLSRKVKSARRTR
                     NLSGEYTASFVCYGYKKDPDDKHKLIIDEEAAKVVVEIFSLIIAGYNASEVARMLNERK
                     IPTRVQNQWKNGINYVPVHNKGDYMWDNSEVIAIVQNEQYKGIMIQNKCETVGFGDNKK
                     VRKRNKEDWSVVEGAIPRIVSDEMFDEVNKMLRVEARGIEKSTKKRKKNLFICPYCGRK
                     LMNSSAVCTPKLLCPKRRMVRTGECQQIFMLKSEAQDKVLEITKEICRTLIQEEELKKA
                     SKDKRKVTSDEYLISELKAEYDRISNSTVSCYQSYREGKYTKEEYVQLRKKNQELLADL
                     ENQISDLQEKVANQEPDAEEKIEQLTQYSMLEQYDGDVLSNIIDKVFIYNDKDIEIVFK
                     GENFIRNAV"
     CDS             complement(11167..12810)
                     /locus_tag="ctg27_15"
                     /transl_table=11
                     /translation="MARKSRTQPKQSTDTLKALSKVYKTAIYVRLSAEKDETRDRKTLI
                     NQRNLIKNFVDQQMDMEVYDIYMDDEISGTTFDRPEFERMMSDMRAGRINCIVVKDLSR
                     LGRDYIETGNLVERVFPMMNIRFVAITDNYDSSKKDADLMVAVTNIANDLYAKDISKKI
                     SSSKQEAMEKGIPTGNVAYGYKVVFNENKVKVMVEDKEAADVVRWIFNEAEKGTLHSVI
                     AAELNAKHILTPAQYKVRHNIEKLEKLRGVKWTVDTISRILKNEVYIGRYVTGKDRVCL
                     YRHEKRHTTNKDEWYVFENHHIALIAKEQFYAVQKNKRKVIKPAKNQTVNMLKGKIICG
                     CCGSSIHIHPEKHAKVYLCTHRKRYGKDSCNCLPVKVDDVYAAVLAVIKEQIQVFVDRE
                     MILKEHHNDSRVIRQEQVYTEAVNKCVKEMDRLMELKSGLYADYTEELLDEKEYLQLNR
                     EYSQRIEKLKIQADEYRQAASQYESAEKTVAQLKAEMLRFKGKRKLTQEMVDLFVAQVR
                     IYENKNLEIVLNYEDELKKFAELNMEREAG"
     CDS             complement(12811..14472)
                     /locus_tag="ctg27_16"
                     /transl_table=11
                     /translation="MNNSKRIYRAAIYVRLSKEDGDLDDVRKAESNSISNQKSLILNYL
                     KDKEDIEIVSIREDDGYSGATFDRPAFKLMMQDVKDGIIDCIVVKDLSRFAREYIDAGR
                     YIERMFPAMGIRFIAINDAYDSADTQAQGNEIIIPFKNLINDAYCRDISIKIRSHLETK
                     RQNGEFVGNYCVYGYKKSEIDHNVIVPDEYAGPVVQDIFHWIKNGMSLDAISDKLNALG
                     ILSPMAYKLSKGENYKTAFQKKDELLWTPVAVRRIATNIIYTGTLVQGKITTPNHKVKT
                     RILKPQEKWAVCHNNHEALVSLRTFQIVQRLLSVDMRMAPGKDSIYLLSGIAVCADCGA
                     LMTRKVSTVNGKKYVYYMCSNNKKNKKCSSHRIKEADLESRVFDTLRDMTAILLDADEV
                     IKEAGNSANFRIDQKKTKERVSAKEKEITKYNQMLVSLYEDYRDGIVDKSDFAIIKESF
                     EVKRAEAEKAIDRLQKEAENIAAGIERDTEWLEEHRKWKTMPSLTRNVVVSLIQSVKVY
                     EGGDIEIVLDCDDEYRKIVARAGELERQYDAERLVV"
ORIGIN
        1 gaaaaataac ctaaaaaaat ttgtctgaaa aagtgttgac aatccatatt gtaccacatc
       61 cgggacaagt gcaaataccg ctgagaggat tggtcctaca ccaagtgagc ggatcacagt
      121 tcctatcaca ataagtgttg tatttccacc ggcaatacct gtaataataa atcccacaat
      181 gatcaatacc gctcccataa gcaggaacgt ttttttattc catttctttg aaacggccgg
      241 cataaaaaaa agaataaaaa taccaggaag ctgtcctgct gtcatgagga ctgacataaa
      301 catcggattt cccaaaacca tattacaata gtaaatctgt gctccaatcg catttgcatt
      361 cataataagt gaaaatgcac cgagcaacaa taataaccag aaatatttat tctttaaagt
      421 tgccgggagc tgctggctca tcggaatacc ggccattttc tttgtatcct catcattgac
      481 catttcttta ttgagcaatc ctgaaatcag aataaggaca cacgcagcaa aacctaaaat
      541 gatgcttgat gtcttccacc caagatttaa tacaagcggc gtaatcagtg agcctgcgat
      601 cagacctatg atattgtttc ccagtgctga aaatgttgca agcattgtag aatcgtcctt
      661 atcatgtgtc atgagtggca gaagggctgt attggaaatt ccataaatag tgtatacaat
      721 acagctcatg aaaatatatg taatgtaagc gtatacaagt tttccattct ctccaagtcc
      781 catgggaaca ttcatcaaaa gaacaattcc caacaatgaa agcggcgctg aagcaatgag
      841 ccatggtctt gctttgccaa gttttgtaga tgtcttatcc acaatgccac ccataagcag
      901 atccgtaata ccatcaaaaa ccctgcacac cagaaacatt gtagcaatgg cacctgcacc
      961 tatcagtgct gtgtctgtgt agtaattgag aagaaatgcc gccgcgatct gactgaacac
     1021 atttcctcca cccgttccaa taccgtacgc cagcttattt ttaagcggca ctttttttct
     1081 gttatccata tttacctccc aaaagatata tttttttgat atctctatta tattttgccc
     1141 tgcgttgaca aacaattcgg gttccgatag aattgagtca gaaacagact taaaggagaa
     1201 cagctgcatg aatactgaga atttaaagga atttattgtt cttgctgaaa caaaaaactt
     1261 ttgggaagcc tctgaacggc tctatatgaa ccagtccacg ttatcaaaac atatcaaaag
     1321 tctggaaaat gacctcggtg tggctttatt tacacgcacc acaagacggg tagaactcac
     1381 aaactatgga gaaatttttc tgccttacgc aaaatccgtt acccgttccg aatttgaagg
     1441 aatttctgct atccagagaa tgcttaatat cgaaaatggt cttctcacca tcggtacgat
     1501 tccttctatg ccacagtatc acatcactca gtttcttgca caatttcaga aattataccc
     1561 cgaaactacc gtacggatca cagaagatga tcctgtaaat ttaatgacat atctggaaaa
     1621 cgaaaaatgt gagctgatct ttaaccgtga agataaagtt acttttgaaa aaaactttct
     1681 caatgaccat cacattttga ggatccctta catgagtgat catctggttg cactgattcc
     1741 actcagccac cctctggcgt cttcttcgtc tattactctg cagcaactta aaaatgatcg
     1801 tttctgtttt ataaaagaag gttccctgat gtaccagatg tcaatggatg catgccagaa
     1861 tgcaggtttt attccagata tcgtttttac cagccacaga attgattcca ttttagacat
     1921 ggtaaccaac caaaactgtg tcgctctgct gatgaacgtt catcttcagc ttccggaaaa
     1981 tggtccaaaa caaaccggtg ctccatggtg tgctgttcct atcacgcctg ttatttcatc
     2041 acagctttca ttatgctacc gctgcgacaa gcctctttca aaaacagcac agttatttgt
     2101 aaatttatgc aacgataaat tgttcaaatc ctgacatata cgcccggtaa attttctatg
     2161 cccacaaaaa aagcagaaaa gatgaattca tcttttccgc cttttttatt cgtacgccat
     2221 tacctcttct aacagttttt ctatttcttc aatcactgtc tttatcccat ccggcgtaat
     2281 tttatcgtag tgaatcccag cagataccac caccggaact aaaaaacgtt catacaactt
     2341 aactgcccac ctgtcactga tcacatgatc cttatgtcct tcaaaaacat gcgagatcaa
     2401 attagatttt tcatctacga tgctcacagc gcctatatgt gacctgtccc cgcctgcgat
     2461 cagcacctgt atcccacatt ccgtcctgca gacggatacc tgtacgatcc tgtctaacag
     2521 tacaatctgt ttttcaatca aatttatcaa tttacaccac ctatcctgat gcgtctctct
     2581 ctacattccg ctccaggatt gcattgtatt atgtaatccc aatatttcca acaaccgttc
     2641 cgcaaaatta tccgtccacg cttcaatcgt cgtatatttt tgataaaaac tgatcattgg
     2701 cggtacaacg cggactccca tggaactcag ctcatgaaga ttcctgagat gaaccggact
     2761 aaggggcgat tctcttgcca caagtactaa ctgtcttgct tctttcaacg tcacatctgc
     2821 tgcacgcagg agcagattat cactgtaacc ggaagcaatt cccgcagctg ttttcattga
     2881 acatggaaca atgatcattg cgtccatttt aaaactccct gacgcaggac attcgccaag
     2941 tgaagacaca tcatacacca catctgcaag tgcctttacc tgctctactg tacaatccgt
     3001 ttcctggaca atagtaagtt ctgccccttt tgtcatgatc agatgtgtct cgacatcagc
     3061 catctctctc agccgtttca acagtctgat cgcgatcgga gctccggatg ccccacttat
     3121 ccctaccaga atttttttca tatcaaataa aatccttcca cttttcctca tcaatatcca
     3181 taaattttgc ccgtgcaaat ttatccttca gttcaaatgg taccgtgcag tcaaaaatcg
     3241 tcttgcagct gattccctta tcggaaatac tctggctgta aaccggatca gaactcgggt
     3301 caagcggatg acaccttacc cctggaattg taatgatatc ccgatctccc tgaaagcgcg
     3361 tattcattgc ccacagaaca tcgcgcgtgt caaaaatatc cacgtcctca tctacgagga
     3421 tcacatgttt caactctgga aacgcgctaa acgccagcag cgctgcctgt ctctgctttc
     3481 cttcatccgt atgcacggtc tttctgcact gaagaactgc catatatttt cctccgcctg
     3541 actgatgcgc ataaacattc gtcaccttcc ccggcaatgc cttctcaagc atattataaa
     3601 tactggcctc tgttggaatt cccgccagat tcacatgctc ttcacttggt ccgatcaccg
     3661 tctgcatgat cggattcttt ctatgcgtaa ccgcctttac ctttataagc cagcactcat
     3721 gacttgccag cccattatat cctgggaatt ccggcatcgc atatcccgta tgtgtattct
     3781 gatcctcaac cactctgatt cccggctgga tttctccttc aatcacatat tcagcatttg
     3841 cgattgcatt ttcttttatg gaaacacatg gtgccagtac caccggagtc tttctgatgg
     3901 cacccgcaat cgaaagttcg ttatacccaa gcggtgtagt tggcggttca aagcaggaac
     3961 caacttctat cgccggatca acaccgatcg aaatagaaat cggaagcggc tgcccgagtt
     4021 ctgtcgccct ttctgccatc acaccgatat gtctgcttcc cggctgtaga aatatggata
     4081 attcatcctt tgactgaatg cacatcctgt ggatcgtcac atccgagcat ccagtatccg
     4141 gatgtgttgc atagcacatc cccattgtga tatatggtcc tgcgtccatt ggagtgttcg
     4201 tcggtgccgg gaataatttg aataagtcaa aatcaggatc cgttacttta tgtatcactt
     4261 cctgacatgg cgccttttcc tctgagacga cgggctcgat cgggtttaaa gccgccctgc
     4321 acaaaagctt tccaagttct tctttcttgc agcccataag tctcgcaaca cgttctctgc
     4381 ttgcaagcag accgatcacc actcgcgcat ccttatgatt ttttatattg ttaaatatca
     4441 tagccggtcc gtcaattttc gtcggacgca tgaccgtacc gcctgctccc acatgcctgt
     4501 acacccctgc aagctccgct tccgggtcca cttcaatatc agtctccacc agttgaccat
     4561 ccatctgtct taacacttca agcgctgatc ttaaatcatt cactaccata attgatatca
     4621 tctccttatt ttaaataatc gattgataac tttattatag tagacatcct gctatagaaa
     4681 aattcaaaat aagggggata ttaattcggt ttgtgactta atgtgaggaa atgttggatt
     4741 tcattaatct tttttataaa aaacttgtga tgtttgtttt ctgttccaac aacagctttt
     4801 taccttgctt ccttttcatc tacccagcag gcacacggtc tcacaatttg tcggttgccg
     4861 aagaagaaca caattcttcg tcattctcca ttcctacaca attctgtctt tcatcgtctg
     4921 atttcatctc atcactaaca ttcaatggta aagtctgatc agccataatc aagccttcct
     4981 tgctaagcaa ctctttttcc tgtaccggac ttgaaatatt ctgactccag aatgtgatat
     5041 gaactcataa tcctattctt tgcccgaata tattcatttt ccgaaatcag gccaaggcga
     5101 accagttttc taagcaccgc cattttcttg ctgaattcca gacactttcc tgcatccatc
     5161 tgataccact ccatagcaaa acctcctctc aaaatacagc ttttcacgaa ttacaaacaa
     5221 ccagtctcac atacacttac aattgctatt cacaccactc cgccagcatt accagttact
     5281 gttcactcgt acctcgttcc agtaacggat tttgccgatg cttcgcattc caaatcggca
     5341 aaatctgcta ccaccactgt atcatacggc attttcagtt cagaaaatgc ctacctgtga
     5401 acagtaacca ttaccaaaca aatattcgat ttttattaaa tagttgtaga acatgcgttt
     5461 gttttatgct atactgattg tatgaatcac ttcacgcttt aatgtttgaa gtaatatttt
     5521 tatatttaaa aagattactc tctcacttat aggagattta gaagcgtttt tgaaaaaatc
     5581 agatttcttg caaaaagtaa gcttctgatg aactctgatt attttatgta taaggcaggt
     5641 attacagata aataaaccat acaaaacaac aggaattgcc ggacttctgt gaatatgagc
     5701 atcctgacag aactcttttg aaacgtgata tacaagccat tgctctgaag cgaatggaag
     5761 atgcggcaag aagtatttct gattttgagg aaatgattag gcaatgggat catctggatg
     5821 acaaccgtga atgaaaagaa cgctatcacg aaatcggcag ggaaaatatc gatagcagga
     5881 aagatgtagc accacttgcc attgtcattc ctgcccctat tgattattct tactggtgac
     5941 agcttatgaa ggtattttcc tcccctatct tttctgtaac taatctcttt acttttttct
     6001 attttgttac tgtttcgttt cctgcaattg tattcttcca taaattcatc atacaaggac
     6061 atcttatacc gaatactctt tatcttttct tctgtatatc ccatacgtct gtgctttttt
     6121 ccacatgcaa catcctccaa tgccggaagt atcttaaact ttaaatccag caattccttc
     6181 actgcctctt tcacatcgct gtaaacacta aaataggaac cgccactatt cagatgtttc
     6241 gctatctgat ttagattgga accaatcttt ccaagctgca tggaatactc ctttaacaga
     6301 cttgtatctc cgtagcatgg aagctttctt cccagagcac atcttctgat atattccgac
     6361 gtagtaagtc cgtttttcct ttctttttcc tctatctgtt ccttatcctc tgcggatata
     6421 cgcaaggaca taagaacctt gttatctttc tttttatctg tatggctatt tctcaaaaca
     6481 ttttcttaag gtacagcttg ttaggtcttc ccaatccctg tctcttccgt tcaagtgctc
     6541 ccaccttttc caattcatcc aataacttgc atgccttttg agttccacaa ttcaaatcca
     6601 cgcaaatatt ttttattgaa taatagataa acaccctccc ttggttgtca atccatccat
     6661 tttttattga caatgaaact cgatctaaaa agagtgcgta taaaagcttt gcatccattg
     6721 acagttcaac aaagccttca tcctctacca gacattttgg cagcttgatg aaagtaaaac
     6781 gctcctcacc ggtgcaatag ttatacttcg gttgaataca taccttttct aaatctctca
     6841 taaacttaat cctttctttt ctctttttac aaattggcaa gcagtgctcc ggtatatacc
     6901 cggcgcattt ttgcttgttg gggaatgccc caatcccctt gaactgcgga taaaccgcag
     6961 agccacgctg acgctttacc ataaaatcac tttttcttct ttgaatcttc ctcataaaga
     7021 tacattactg cctcaagtgt ttttttcaga aactttgttt gttcattatg catcttctct
     7081 atttctgcaa tatcctcttc gtacaatttt ccggtttcat ttgctttcct tgcatactga
     7141 ttgagattat tactaatcct tgaatgcaag gatattacct gatccagatc cggccactta
     7201 ggaataatca catatccgtt caatgccatc tttctgatat atgcactcat gttttgaact
     7261 ccagcttcct tcattcgatt atgcagtatc tccacctctt ccggtttgaa ttttacataa
     7321 attccttttg aatactcttt cacttttctt ttcctccatt tcttttcaaa tttgtaattt
     7381 ttagaaatca ttcttccgag ggcaatcggc aatttctaaa attgggcaac aaaaaagcaa
     7441 ccgatattac tcgattgcca ctctgttact cttgcgaaac tattcctttt tcaaaaaatt
     7501 tataaatatt gcctaaatgc ttttgtgaac tttttccttc aaaaaacatt acaaattgat
     7561 aattgacttt ttgaaaatta ctgttctcaa gtttctatca aaattagaaa aagcccaaac
     7621 cacaagggtt tgagcttcat ttgcacattc acgttttctg tttttgggta tagaatctct
     7681 actgttaaat atagagtatt ggtttgattt tgtcaagtct tagttcttat ctatattctt
     7741 ccgttaaata aaaaagtaaa tttcacattg gacttaagta gttatttcag tttttcatat
     7801 atctcatcag ttactgtttc acaccatttg gatgatgttt tttctcccgg tacttcaatt
     7861 gccagatgtg aaaaccattc atctggtgct gctccatgcc agtgttttac ttctgccgga
     7921 atattgacac aatctccagg tttcatttct actgcttctt ttccttcttc ctgatagtat
     7981 ccacgtcctg caatgcagat aagaatctgt ccgcctccgc tttttgcatg atgaatatgc
     8041 cagttattcc tgcaactagg ttcaaaagtc acattgaaaa ttccaacctg tgacgtagac
     8101 acaggagcca aaaaactttt ccctgtaaaa tattgtgcaa atttatcatt tggctctcca
     8161 atcgggaata tcatcttttt agcatgagct ctcattgctt catcttcata tgaaagatca
     8221 ccttcgtcta tactccagac atcttttgca agattgaatg ccgcccatcc ttttggccac
     8281 cctgcataaa atgctatatg ggtaatcacg gctgcaattt ctttctgagt cactccatga
     8341 gcttttgcat tttcaaaatg atgtactaaa gatgtattaa tcattcctga agcgataagt
     8401 gctgtgactg ttataataca tcttgtcttt acatcaatat cctgattatt ccagttttct
     8461 ccaaacaaaa catcatcatt aaaatgtgca aactgtggtg caaattcatt cagtgcgttt
     8521 cttcctgctg tctgtacaat ttttttcact ttaatcacct gtccttattt taactttgct
     8581 ccatccttaa aagcatttcc cacacgttct ccaagtctgt aatatccgtg atgtaccgga
     8641 tcatatgtaa ttggtgtaaa cttactaaga tcaatttctc cgtcatcacc gagatatttc
     8701 tcatctgcac ttacattttt aatttccgca agatacttgc tgccatcaat gacttttaca
     8761 agttcacact caagagtcaa tggaagttca ttgatgattg gtgcatttac aaattcacct
     8821 ttcgttgtag taaagcctgc ttttttcatc ttatctgctt ctttatttgc agaaacaatt
     8881 cccacataat cgcaggcaac cagatgttca agatctgcca cccctactgt aaaagcctta
     8941 ttttttataa tattgtctgt tgtcttatgg gcagacaaat ctacaataat ctcatttgca
     9001 cctacaattc cgccccatgc agcgttcatt gcatttgcct ttccattttc atcataggtt
     9061 cccagaatca taaccggctg tggatataaa aatggctttg ctccaaaatt ttttctcatt
     9121 gttttatctc tccttatggt tatttgttta tatcagtatt tatctgccca atccattctg
     9181 taatcacctc ttctgaagtt tccagatgat cttttccttt ggaatcaaac tgaatctgca
     9241 tttcatgtgc aaaggcagct cctttgcaat tttcctccat atcttttata acatgccccg
     9301 gccatccacc atttgtcata aatggaatca ctgtctttcc tgtaaaatca tttgttgtca
     9361 aaaatgtaag cactgcaggt gccatcgtat accaccacgt tggagtgcct gcatctgtca
     9421 agactgggac aaaaaaaatt ttattttttt ctgtacatat tctatcaaac ccttactgat
     9481 ttttaaagta cagaatagtt tattactatt aaccttttcg ttattaccca tagaagaagc
     9541 cagcagcttt ttcactactg gctttctgta ttactcattt tgtttactac actgcatttc
     9601 ggataaagtt ctcaccctta aacacaatct ctatatcttt atcgttgtaa atgaacacct
     9661 tatcaattat gtttgaaagt acatctccgt catactgctc cagcatacta tactgggtta
     9721 gctgttctat cttctcctct gcgtcaggct cctgatttgc aactttctcc tgcaaatctg
     9781 atatctgatt ctccagatca gctaacagct cttggttttt ttttcttagc tgcacatatt
     9841 cttcttttgt gtactttccc tctctgtatg actgataaca agaaactgtg ctgtttgata
     9901 ttctgtcata ctccgcttta agctcactaa tcaaatactc atcgcttgtc accttccttt
     9961 tatcctttga tgccttttta agttcttctt cctgtataag tgttctacag atttcctttg
    10021 tgatttccag caccttgtcc tgtgcttctg acttcagcat aaaaatctgc tgacattcgc
    10081 cagtccttac catcctgcgt tttggacaga ggagcttcgg tgtacatact gcactggaat
    10141 tcatcagctt tcttccacaa tagggacaga taaaaagatt tttcttacgt ttctttgtac
    10201 tcttttcaat ccctctggct tcaacccgta gcattttatt gacttcatca aacatttcat
    10261 cgcttactat tcttggtatt gcaccttcta caacagacca gtcctcttta tttcgtttgc
    10321 gaaccttctt attatctcca aaaccaacag tttcacattt attctggatc attattcctt
    10381 tgtactgctc attctggaca atcgctataa cttctgaatt atcccacata taatcccctt
    10441 tattatgaac cggaacataa ttgattccat tcttccactg gttttgaact cttgtcggga
    10501 tttttctctc atttaacatg cgggcaacct cacttgcatt atatcctgca atgatcagtg
    10561 aaaatatctc cacaacaacc tttgcagctt cttcatctat tatcagctta tgcttatcgt
    10621 ctggatcttt cttgtatcca tagcagacaa atgatgccgt gtattcgcca ctcagatttc
    10681 ttgtccttct ggcactcttt acctttcttg ataaatccat actgtaaagc tggtaaatca
    10741 gattcttata agctacatcc attcctccag taacaccaaa gtttctgtca ctgtcataat
    10801 tatcgttgac agaaataaac ctcattccca ttgcagggaa tacaaactcc agatagttgc
    10861 ctacttcaag gtaatccctt ccaaatcgtg aaaagtcttt tactatgata cattcaaatc
    10921 ttccaagctc tgcgtcctgt atgagccttt ggaattctgc tctgttattg aacattgttc
    10981 ccgaatatcc gtcatcaaag tattccagta cctcaaaacc tgcaaattcc tctgttttct
    11041 tgatatacgc atacaagagt tttctctgtc ctgtaatact gttactttcg tcttttgttc
    11101 ctgcttttac ctcctcatcc gcatcagaga gacggatata aaaggctaat tttcttttct
    11161 cagccattat cctgcctctc tttccatatt cagttctgcg aattttttca gttcatcttc
    11221 atagttcaga acgatctcaa gattcttgtt ttcgtatatg cgtacctgag ctacaaacaa
    11281 atcgaccatt tcctgcgtca acttgcgttt tcctttaaaa cggagcattt cagcttttaa
    11341 ctgggcaaca gtcttttcag cactttcata ctgacttgcc gcctgcctgt attcatcagc
    11401 ctgtatcttc aatttctcaa tacgctgcga atactccctg ttcagttgca ggtattcctt
    11461 ttcatcaagc agttcttctg tgtaatctgc atacaagccg ctctttaatt ccataagtct
    11521 gtccatttcc ttgacacact tattcacggc ttccgtatat acctgttcct gtctgattac
    11581 cctgctgtca ttgtggtgtt cctttaatat catttccctg tcaacaaaga cctgtatctg
    11641 ctcttttata acggcaagca ccgctgcata tacatcgtct acctttacag gcaggcagtt
    11701 acaactatcc tttccatatc tttttctatg cgtacacaga taaacctttg cgtgtttctc
    11761 tgggtgaata tggatactgc ttccacaaca gccgcagatg attttgcctt tcagcatatt
    11821 cactgtctga ttttttgctg gctttattac ctttcttttg ttcttctgta ccgcatagaa
    11881 ctgttccttt gcaataagtg caatatgatg attttcaaaa acataccact catctttatt
    11941 ggtagtatgc ctcttttcgt gtctgtacag gcataccctg tctttacctg tcacatatct
    12001 tccaatatag acttcattct ttaaaatgcg tgatattgta tcaacagtcc acttaactcc
    12061 acgcagcttt tcaagtttct ctatattatg ccttactttg tactgggcag gtgtaaggat
    12121 atgcttcgca ttcagttctg ccgctatcac agaatgcagt gtaccttttt ctgcctcatt
    12181 aaaaatccac cttacaacat ctgcggcttc cttatcctca accattacct tgactttatt
    12241 ttcattaaag actaccttat agccataagc cacatttcca gtcggaatac ctttttccat
    12301 cgcttcctgc ttactggaag atattttctt tgaaatatcc ttagcataca ggtcattggc
    12361 tatattcgtg accgcaacca taaggtctgc gtctttcttt gaggaatcat aattatccgt
    12421 aatcgctaca aagcggatat tcatcatcgg gaatacacgc tctaccagat tgcccgtttc
    12481 aatgtaatct ctacccaagc gggacaaatc ctttacgaca atgcagttga tccttcctgc
    12541 cctcatatcc gacatcatgc gttcaaattc cggtctgtcg aatgttgtac cggaaatttc
    12601 atcgtccata tagatgtcat aaacttccat gtccatctgc tgatccacaa agttcttaat
    12661 gagatttctc tgattgatca gggtttttct gtctctcgtt tcatcttttt ccgcagataa
    12721 cctcacatat atggcagtct tatacacttt ggataaagcc ttcagcgtat ccgtggactg
    12781 tttcggctgt gttcttgact tccttgccat ttaaaccacc agcctttccg catcatactg
    12841 tctttccagc tccccggctc ttgcaacgat ttttctgtat tcatcgtcac agtccagtac
    12901 gatttctata tcaccgccct catatacctt tacagactgt ataaggctta ctaccacatt
    12961 acgggtaaga gaaggcattg ttttccattt cctgtgttct tccagccact cggtatccct
    13021 ttcaatcccg gcagcaatgt tttccgcttc cttctgcaac ctgtcgattg ccttttccgc
    13081 ctctgctctt tttacctcaa aactctcctt gataatcgca aaatctgatt tatcaacaat
    13141 tccatctcgg taatcctcat aaagcgaaac aagcatctgg ttgtatttgg ttatctcttt
    13201 ctcttttgca ctgaccctct cttttgtctt tttctggtct attctgaaat tggcactatt
    13261 gccagcttcc tttattacct catctgcatc cagaagtatt gctgtcatat ccctcaaggt
    13321 atcaaataca cggctttcca agtctgcctc ttttatcctg tgggagctgc acttcttatt
    13381 cttcttgtta ttggaacaca tatagtaaac atactttttt ccatttactg tagacacctt
    13441 tcgtgtcata agtgccccac agtcggcaca tactgctatt ccggataaaa gataaataga
    13501 atcttttccc ggtgccattc tcatatccac tgacaacaga cgctgtacaa tctggaatgt
    13561 tcttaaagat accagtgcct cgtgattgtt gtggcatact gcccatttct cctgtggctt
    13621 taatatcctt gttttaacct tatggttagg tgttgtgatt ttgccctgta caagcgttcc
    13681 tgtataaata atattcgttg caatacgcct tacagcaaca ggagtccaca acagctcgtc
    13741 tttcttctga aatgctgtct tataattctc tcccttgctg agcttatatg ccataggtga
    13801 gagaatacca agagcattca gcttgtcact tatggcatca aggctcattc cgttctttat
    13861 ccagtggaaa atatcctgaa ccaccggacc agcatattcg tcaggaacaa tcacattatg
    13921 gtcaatctca gatttcttgt agccatagac acagtaattt cctacaaatt ctccgttctg
    13981 tctctttgtt tcaaggtggc ttcggatttt tatggaaata tccctgcaat aagcgtcatt
    14041 gataagattc ttaaacggaa tgattatctc gtttccctgt gcctgtgtat ctgcactgtc
    14101 ataggcatca ttgatcgcta taaatcgtat ccccattgca ggaaacatcc gctcaatgta
    14161 tctccctgcg tcgatatact ctcttgcaaa cctcgaaaga tcttttacaa cgatacagtc
    14221 tataataccg tctttcacat cctgcatcat aagtttaaat gccggacggt caaaagttgc
    14281 ccctgaatag ccgtcatcct cacggattga tactatttca atatcttctt tgtcttttaa
    14341 ataattaagt atcagggatt tctgatttga gatactgtta ctttcagctt ttctcacatc
    14401 atcaagatcg ccatcttcct tagataatct aacatagatg gctgctctgt aaattctttt
    14461 agaattgttc atgtccacca ctccttcgat tttctaagtt agaagtccca aatcaagagg
    14521 aatggaaaca taaatatgaa attgataccc tttcgggtta gatgtcctta tttgtctgta
    14581 atgatatcac aaatccatct gaatttcca
//
