GCA_003471295.1 - 2 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaPAAIFKMA_1 (original name was: gnl|Prokka|PAAIFKMA_1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	lanthipeptide-class-iv	189,254	211,911
Region 1.2	NRPS-like	474,313	516,187

Region	Type	From	To	Most similar known cluster	Similarity
Region 1.1	lanthipeptide-class-iv	189,254	211,911
Region 1.2	NRPS-like	474,313	516,187

No secondary metabolite regions were found in these records:: gnlProkkaPAAIFKMA_2 (original name was: gnl|Prokka|PAAIFKMA_2); gnlProkkaPAAIFKMA_3 (original name was: gnl|Prokka|PAAIFKMA_3); gnlProkkaPAAIFKMA_4 (original name was: gnl|Prokka|PAAIFKMA_4); gnlProkkaPAAIFKMA_5 (original name was: gnl|Prokka|PAAIFKMA_5); gnlProkkaPAAIFKMA_6 (original name was: gnl|Prokka|PAAIFKMA_6); gnlProkkaPAAIFKMA_7 (original name was: gnl|Prokka|PAAIFKMA_7); gnlProkkaPAAIFKMA_8 (original name was: gnl|Prokka|PAAIFKMA_8); gnlProkkaPAAIFKMA_9 (original name was: gnl|Prokka|PAAIFKMA_9); gnlProkkaPAAIFKMA_11 (original name was: gnl|Prokka|PAAIFKMA_11); gnlProkkaPAAIFKMA_12 (original name was: gnl|Prokka|PAAIFKMA_12); gnlProkkaPAAIFKMA_13 (original name was: gnl|Prokka|PAAIFKMA_13); gnlProkkaPAAIFKMA_14 (original name was: gnl|Prokka|PAAIFKMA_14); gnlProkkaPAAIFKMA_15 (original name was: gnl|Prokka|PAAIFKMA_15); gnlProkkaPAAIFKMA_16 (original name was: gnl|Prokka|PAAIFKMA_16); gnlProkkaPAAIFKMA_17 (original name was: gnl|Prokka|PAAIFKMA_17); gnlProkkaPAAIFKMA_18 (original name was: gnl|Prokka|PAAIFKMA_18)

Compact view

gnlProkkaPAAIFKMA_1 - Region 1 - lanthipeptide-class-iv

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Location: 189,254 - 211,911 nt. (total: 22,658 nt) Show pHMM detection rules used

lanthipeptide-class-iv: (cds(LANC_like and Pkinase) and not micKC)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Lanthipeptides

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

Lanthipeptide predictions

Lanthipeptides - No core peptides found.

Lanthipeptides

Core peptide predictions

No core peptides found.

gnlProkkaPAAIFKMA_1 - Region 2 - NRPS-like

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Location: 474,313 - 516,187 nt. (total: 41,875 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 2, location 474312 - 516187:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg1_449

AMP-binding (14..381): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DFFTIGIIYK
Nearest Stachelhaus code(s):: Ile DFWNIGIIYK (56% 8Å match)
Stachelhaus code match:: 80% (moderate)