LOCUS       gnlProkkaJLPOELPL_22    7850 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JLPOELPL_22.
ACCESSION   gnlProkkaJLPOELPL_22
VERSION     gnlProkkaJLPOELPL_22
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 01:59:09
            Original ID  :: gnl|Prokka|JLPOELPL_22
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7850
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..7850
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[734:5008]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      735..5008
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..7850
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..7850
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(57..704)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_1"
                     /sec_met_domain="Polysacc_synt (E-value: 7e-09, bitscore:
                     24.9, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVVFNSNKFFCWINQALITCVSRIICVIETLVPSKFSDKIRILR
                     SHEVVFYNVIGLTFFNSLGGLLTILTQVKLANVMGASHYGVYSYCLAIGEVGAMVVRYG
                     RHKTMVRDLIQYPVRNLQLISSTFIIGVINFLIFLGLVLVFHQDIDIQISVGTVLLICG
                     ACLISLDFQPVYESLNAMSWHSMYNLFQKLIFVIILWGIMLSPFTLSLNVLG"
     CDS             complement(735..1844)
                     /NRPS_PKS="Domain: Aminotran_5 (30-298). E-value: 6.3e-34.
                     Score: 109.3. Matches aSDomain:
                     nrpspksdomains_ctg22_2_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 80.5; E-value:
                     1.9e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_2"
                     /sec_met_domain="Aminotran_5 (E-value: 7.9e-32, bitscore:
                     99.9, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIERKILLNPGPATTTDTVKLAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGDLSKHTAVLFCGSGTINIDICLNSLLPADKKVLVVNNGAYSTRAVEVCEYY
                     GLPHIDLKFSVYELPDLSVIEKTLSDNPDIALVYTTHHETGTGILNPIREIGKIAHSHG
                     AVFVVDTTSSLGMIPFDIGKDNVDFCMASAQKGLQAMTGLSFIIGDESLIRASRDYPKR
                     SYYCNLYLQYDYFEKTGEMHFTPPVQTVYAARQALDEYFAVGEEAKFARHKRVFEAIHK
                     GLQELGLQYAIKREWQSGLVVSVLYPDDPLWDFDKVHDYCYERGFTIYPGKISTTNTFR
                     LCALGEIDVEDIERFFEVMREAQYLLFIR"
     aSDomain        complement(951..1754)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg22_2_Aminotran_5.1"
                     /evalue="6.30E-34"
                     /label="ctg22_2_Aminotran_5.1"
                     /locus_tag="ctg22_2"
                     /protein_end="298"
                     /protein_start="30"
                     /score="109.3"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGDLSKHTAVLFCGSGTINIDICL
                     NSLLPADKKVLVVNNGAYSTRAVEVCEYYGLPHIDLKFSVYELPDLSVIEKTLSDNPDI
                     ALVYTTHHETGTGILNPIREIGKIAHSHGAVFVVDTTSSLGMIPFDIGKDNVDFCMASA
                     QKGLQAMTGLSFIIGDESLIRASRDYPKRSYYCNLYLQYDYFEKTGEMHFTPPVQTVYA
                     ARQALDEYFAVGEEAKFARHKRVFEAIHKGLQELGLQYAIKREWQS"
     CDS             complement(1841..2977)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 70.6;
                     E-value: 1.9e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_3"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.5e-22, bitscore:
                     69.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5e-21, bitscore:
                     64.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSVEKIYDTFLHHGVDFFTGVPDSLLKNICAYITDHAPRGKHII
                     AANEGSAVGIACGYYMASGNVPLVYMQNSGLGNTVNPLLSLADEKVYSLPLLLLVGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMKIPFIILDTDEDEALAQIHDAVVSAKSRSIPHAIV
                     IRKDTFGKYKLRQEALNDYPLSREEALMQVVDHLGDNDIVVSTTGKLSRELFEYRESKG
                     QGHARDFLTVGSMGHSSSIALGIALEKPDRRVYCLDGDGAFIMHMGAVSNIGDLSPKNY
                     RHVLFNNGAHESVGGQPTLGFRLDIASIAKGCGYAHVLTASDKEGLSCALEKLSGLSGP
                     VLLEIKVRIDSRDDLGRPTTTPVENKEHFMAFLKDTHS"
     CDS             complement(2989..4290)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 214.1;
                     E-value: 3.9e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_4"
                     /sec_met_domain="CTP_transf_like (E-value: 1.3e-12,
                     bitscore: 37.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 9.2e-123, bitscore:
                     398.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 4.6e-65, bitscore:
                     208.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKIYVGMTADIMHPGLIHIIHEATKYGDVIVGLLTDKAIAEHK
                     RLPYLTYDQRKEVVENIKGVFEVVPQEDWSYVPNLEKLKPDYIIHGDDWKTGPLREVRE
                     QVFEVMNAQGGKVIEIPYTRGINSSSLDKDIKAIGTTPDVRLKSLRRLIQAKPVVRILE
                     AHDGLCGLIIENLEVQKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAVIIEDKVGLKKNSLFGTDAIQTQDS
                     IEGFCDKIRAGKNAQVTGDFMIIARIESLIAGKPMSDALERAYAYVQAGADGIMIHSKD
                     KSGEDIREFCRTFRKEYAHVPIVVVPTTYDHVHESELHEWGANVVIYANHLLRAAYPAM
                     MNVARTILENERAEEVRPLCMPIKEILELIPGTK"
     CDS             complement(4310..5008)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_5"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.2e-14, bitscore:
                     44.4, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAGLGTRFGHYTELVPKGFVEVGGKPMIIRSIETLLSCGIERII
                     LGTGYKKEAYEALQADFPQIETCFSPRYADTNSMYTLYNTRDVIGDDSFLLLESDLVFE
                     RKAILSLLDDEFPDVMLVSSLTKFQDQYYVEYDRNHILTSCSVDKNALEAKGELVGIHK
                     LSNTFYRRMCADYATILESQPKLGYEYELLRMSRSVSPVRVLRVEGLKWYEIDDEADLS
                     YAEEHIIRYC"
     CDS             complement(5022..6077)
                     /locus_tag="ctg22_6"
                     /transl_table=11
                     /translation="MKAGHRIYYIIGLLTFSEVALLGFALLPVPLKVCSIFLSGLPLGM
                     IWGVIFSYIEGRRISEILNVGLSVALIVSSGLVKTLGQFVMDNLHVSEYWMPFTTGLLV
                     YPVMLLCSWLLNQIPAPNEQDIIQRTKRAPMDGKDRRKFLRQFFWGICMLVVFYGALTV
                     FRELRDSFAADIWKELHIEGAMIFTQTEVPIAVFVLVLMFLIVFVRNNRLALNIIYCIA
                     VTGGSLMVFSTLLYVYGFLSPIWWMILSGLGLYMGYIPFTYLIERLIASLRVVSTAVFI
                     IYLADSFGYLGTTGVFMVKNFVSADISWTVMLMRTALFSGFVSVLSIFAIYCYFKQQLN
                     SLILIPSEIHD"
     CDS             complement(6074..6304)
                     /locus_tag="ctg22_7"
                     /transl_table=11
                     /translation="MIRSFLSRSPLYVLALYASVLIFLVYTCAYAYRKPFTAAIYEGEI
                     LWGFDVKILYVLSEIIATPFPSSSVFVFCLR"
     CDS             complement(6301..6786)
                     /locus_tag="ctg22_8"
                     /transl_table=11
                     /translation="MLSLQSEIDSLCAVSHELLHLGLDGEPIYSDRFRQLNTDVYHRCE
                     HLFGSHGRTLEEEASLCIALLTGYNATIYNHGDKEDKIQSVLNRSWDLLDTLPASLLKC
                     RLLVACYAEVFDEELAAEAHAIIDGWKDRELTREECEIVEHLKSLEANPYPYSELHE"
     CDS             complement(6845..7423)
                     /locus_tag="ctg22_9"
                     /transl_table=11
                     /translation="MFHYPGVPQLYPFVNNSINKSWYALRITYSRELAFKEYLDSRGVR
                     NFLPMRYEYVFRGERKIRKLVPVVHNLVFVYATRSEVDEMKSTVGASLPIRYIMDRETR
                     QPITIPEVQMRSFIAVAGNYDEQVVYLDPSVVSMKKGDRVRVTGGIFEGVEGEFVRIKG
                     DRRVVVSIQGVMAVATAFIHPSLIELIKN"
     CDS             complement(7470..7688)
                     /locus_tag="ctg22_10"
                     /transl_table=11
                     /translation="MKENIFFIKHFCSYENTLYLCVQLNDRLLKHFRFIIDSFTDCKIS
                     KALFFQTSFSVLLFQTVSPAIGEYLMK"
ORIGIN
        1 cgaagttatt tctttatatt gccatacaat tactagtatc caagaaaaga agaatactat
       61 cctaatacat tcaaagataa agtaaatgga gacagcatta ttccccacaa gataataaca
      121 aatatcaatt tctgaaacaa attatacata gaatgccaac tcattgcgtt taaagactca
      181 tatacaggtt gaaaatccaa tgagatcaaa caagcaccgc atataagcaa cactgttcct
      241 acagaaattt gaatatctat atcttgatga aaaacaagaa ctagccctaa aaaaatcaaa
      301 aaattaatta ccccaataat aaatgtggaa gaaataagtt gtaaatttct aaccggatat
      361 tgtataagat ctcgtaccat tgttttatgt cgcccatagc gaactaccat agcaccaact
      421 tctccaatag ctaaacaata tgaatatacc ccataatgag aagctcccat tacattggct
      481 agctttactt gtgtcaaaat agtcaataat cctcccaacg aattaaagaa tgtcaatcct
      541 attacattat aaaacacaac ctcatgactt cttaaaatcc ttattttatc actaaattta
      601 gaaggaacca aagtttcaat gacacaaatt atcctactaa cgcaagtaat taaagcttga
      661 tttatccaac aaaaaaattt atttgaatta aacacaacat ccattctaaa gaaacatttc
      721 ttccaatcaa cgacctatct tataaatagg agatattgtg cctccctcat cacctcaaag
      781 aacctctcaa tatcctccac atcaatctct cccaacgcac aaagccggaa tgtattcgtt
      841 gtggaaatct tacccgggta gatcgtaaag ccacgttcat agcagtaatc atgaacctta
      901 tcaaaatccc agaggggatc atcaggatac aatacagaaa caacaagacc cgactgccat
      961 tcacgtttga tcgcatactg aagaccaagc tcttgcaaac ctttatggat ggcttcaaag
     1021 accctcttgt gacgggcgaa tttagcctct tcacctactg caaaatattc atcaagagcc
     1081 tgacgggcag cgtaaacggt ttgaacagga ggagtaaaat gcatctcacc cgtcttctca
     1141 aagtaatcgt attgtaaata gaggttacaa tagtaggagc gtttcggata atcccttgaa
     1201 gcacgtatca gggattcatc acctatgata aaggaaagac ccgtcatggc ctgaaggcct
     1261 ttctgagccg aagccataca aaagtcaaca ttatccttcc cgatatcaaa aggaatcata
     1321 cccagggaag aagtggtgtc gacaacaaaa acggcaccgt gcgaatgggc tatttttccg
     1381 atctcacgga tggggttcaa gatacccgta cccgtttcat ggtgcgtggt atagaccaaa
     1441 gcgatgtccg gattgtcgga aagcgtcttt tcgattaccg acaggtcggg aagttcgtaa
     1501 acggaaaact tcaaatcgat atggggaaga ccgtaatatt cgcagacttc caccgcacgg
     1561 gtgctgtagg caccgttatt gacaaccaga actttcttat ccgcaggaag aagagagttc
     1621 aggcagatat cgatattgat cgtacccgag ccgcaaaaca ggacggccgt atgtttggag
     1681 aggtctccat gcgcaacgcg gaccaggtcg tcacgtaact gtttcatcat acccgcaaac
     1741 tctttctcac gcggacagat atcgggaaca acctgcgcca gcttcaccgt atccgtcgtg
     1801 gtggcgggac ccggattcaa aaggatcttt ctttcgatat tcatgaatgc gtatctttta
     1861 aaaatgccat aaaatgctct ttattctcta ccggagtagt cgtagggcga cccagatcat
     1921 cacgtgaatc gatccggacc ttaatttcaa gaagaaccgg gccggacagg ccggacagct
     1981 tctcaagcgc acacgaaagc ccttccttgt cggaggcagt cagtacatgc gcataaccgc
     2041 aacctttcgc tatcgaggcg atatccagac ggaaaccgag cgtgggttga ccgccgacag
     2101 attcatgcgc accgttgttg aaaaggacgt gcctgtaatt cttgggagaa agatcgccga
     2161 tattgctgac agcacccatg tgcatgataa aggcaccgtc accgtcaaga cagtagacac
     2221 ggcggtcagg cttctcaagg gcaatcccca gggcaatgga agaactgtga cccatggaac
     2281 ccacagttag gaaatccctt gcgtgcccct gccctttcga ttcacggtac tcgaaaagct
     2341 cacgggagag cttgcccgtg gtggaaacca caatgtcatt gtccccgagg tggtcgacaa
     2401 cctgcattag cgcctcctcg cgggacagag gatagtcatt caaggcttcc tgacgcaatt
     2461 tatattttcc aaacgtatct ttacggatga caatcgcatg gggaatcgac cggctcttcg
     2521 ccgagacaac cgcgtcatgg atctgcgcca gggcctcgtc ttcatccgta tccagaatta
     2581 taaaaggaat tttcatggct ttcagaagat caagggtaac ctcgccctgc ttcttatgct
     2641 ggggttcgtc ttttgtgccg ggctcaccgc gccagccgac cagcaaaaga agaggaaggc
     2701 tgtacacttt ctcgtccgca agggacaaga ggggattcac cgtatttccc agaccggagt
     2761 tctgcatata aaccaaagga acgttgccag aagccatata ataaccgcag gcaatgccca
     2821 ccgcggaacc ttcattggcg gcgatgatat gcttaccacg cggagcatga tccgtgatat
     2881 aggcgcaaat attcttcaaa agggaatcgg gaacacccgt aaagaagtca acaccgtgat
     2941 gaaggaacgt atcgtatatc ttttctacac ttaccataac cgtctgattt atttagtgcc
     3001 cggaatcaat tccagaattt ccttgatagg catacaaagc ggacggacct cctcggcgcg
     3061 ctcgttttca aggatggtcc tggccacgtt catcatggcc gggtaagcgg cacggagaag
     3121 gtggttggcg taaatgacta cgttggcacc ccattcgtga agttcggatt cgtgcacatg
     3181 gtcataagtc gtcggaacaa cgacaatggg aacatgggcg tattctttgc ggaaagtccg
     3241 gcagaactca cggatatcct cacccgactt atccttgctg tggatcatga tgccgtccgc
     3301 acccgcctgt acataggcat aagcacgttc gagggcgtca ctcatgggtt tgccggcaat
     3361 aaggctttcg atacgcgcaa tgatcataaa gtcaccggtg acctgggcat tcttccctgc
     3421 tctgatctta tcgcagaaac cctcgatact atcctgagtc tggatagcgt cagtaccaaa
     3481 aagggaattc ttcttcagac cgactttatc ttcaatgatt accgcagaaa tgccgtgacg
     3541 ttccagagtg cgcacagtaa agacaaagtg ttcgatcttg ccacccgtgt ctccatcaaa
     3601 aataataggc ttggtggtgc attcaaggat attgttcagg tcctgtaaac gggtggtaag
     3661 gtcgaccgct tcaatatccg gtttaccctt actcgtggag tcggtcaggc tgctggacca
     3721 catgccgtca aagacctcgc gcttatcacc cttctggact tcaagattct caataatcag
     3781 accgcaaaga ccgtcgtgag cctccaggat acggaccaca ggcttggcct ggatcaggcg
     3841 gcggagggac ttaagacgta cgtcaggggt agtcccgatc gccttgatat ccttgtcgag
     3901 cgaggaggag ttgatgcccc gggtataagg gatctcgatt accttgcccc cctgggcgtt
     3961 catcacctca aaaacctgtt cgcgcacctc gcgcaacggg cccgttttcc agtcgtcgcc
     4021 gtggatgata tagtcaggct tgagtttttc cagattcgga acatagctcc agtcctcctg
     4081 gggaacaacc tcaaaaaccc ccttgatatt ctcaacaacc tccttacgct gatcataggt
     4141 aaggtaaggg aggcgtttgt gttcggcgat ggccttgtcc gtcagcagac cgacgatgac
     4201 atcaccgtat ttagtagctt catgaataat atggatcagc cccggatgca tgatatccgc
     4261 ggtcataccg acatagattt tcttgttcat atatggaaaa gatttgtttt taacaatagc
     4321 ggatgatgtg ctcctcggca tacgaaaggt cggcttcatc atcgatttca taccatttaa
     4381 gaccctccac cctgagcaca cggacagggg aaacggaacg ggacatgcgg agcagttcgt
     4441 actcgtaacc cagtttaggc tgggactcca ggatggtcgc ataatcggcg cacatccggc
     4501 ggtagaaagt attggaaagt ttatggatac cgaccagctc gccttttgcc tcaagggcgt
     4561 tcttgtctac cgaacaggaa gtaaggatgt gattgcggtc atattccaca taatactgat
     4621 cctggaactt ggtcagagaa gagacaagca tcacatccgg gaattcgtca tccagtagcg
     4681 agaggatggc cttgcgttca aaaacaaggt ccgattcaag cagcaggaaa ctgtcatcgc
     4741 ctatcacgtc acgcgtattg tacagagtgt acatactgtt agtatcggca tagcggggac
     4801 tgaaacaggt ctctatctgg gggaaatccg cctgaagggc ttcataagcc tcttttttat
     4861 aacccgtacc gaggatgata cgttcgatac cgcaggaaag aagggtttcg atagagcgga
     4921 taatcatagg ttttccacca acctccacaa aacctttggg cacaagctcg gtataatgcc
     4981 cgaagcgggt accaagaccg gcagccatga tcattgctgt tttaatcatg aatttcagag
     5041 ggaattaata taagtgaatt caattgttgc ttgaaataac agtaaatcgc aaaaatcgac
     5101 aggacagaaa caaatcctga aaaaagggca gtacgcatta gcatgacagt ccaggaaatg
     5161 tcagcagaaa cgaagttctt gaccataaac acacccgtag tgcccagata gccgaaagaa
     5221 tcggccaaat aaataataaa aacagccgta ctaaccaccc taagggaagc aatcaggcgt
     5281 tctatcaggt aagtgaaagg aatatacccc atatacagac caagaccgga aagaatcatc
     5341 caccaaatag gagaaagaaa accgtacaca taaagcaatg tggaaaaaac cattaaggaa
     5401 ccgcctgtaa cggcaatgca ataaataata ttaagagcca aacggttatt acggacaaac
     5461 acaatcagga acatcagtac aaggacaaaa acggcaatgg gaacctctgt ctgagtaaag
     5521 atcattgcac cttcaatatg gagctccttc caaatatcgg cagcgaaaga gtcacgaagc
     5581 tcacggaaca cggtcagggc accgtaaaaa acaaccagca tgcagattcc ccagaagaat
     5641 tgcctcaaaa atttacgcct gtctttacca tccatcggag cacgtttggt acgctgtatg
     5701 atatcttgct cattgggagc cggaatctga ttgagaagcc agctgcaaag caacataaca
     5761 gggtatacca acaaaccggt ggtaaaaggc atccaatatt ccgacacatg caaattatcc
     5821 atcacgaatt gtcccaaggt tttcaccaaa ccggaagaga ctatcaaagc aacgctcagc
     5881 ccgacattca atatttcact gatacgacgc ccttcgatat agctaaaaat gacaccccag
     5941 atcataccca ggggaagacc gctcagaaaa atagaacaca ccttcaaagg aaccggaaga
     6001 agtgcaaaac ccaacaaagc aacttcggaa aaagtaagca gccctattat ataatagatg
     6061 cggtgacccg ctttcatcga aggcagaata cgaacaccga tgaacttgga aagggcgtag
     6121 cgataatctc agaaaggaca tacaggattt tgacatcgaa tccccaaaga atctcacctt
     6181 cataaatggc tgcggtaaat ggcttacggt aggcataggc acaagtataa accagaaaaa
     6241 tcaaaacgct ggcatagaga gccaaaacgt aaaggggaga acgggaaaga aaggaacgaa
     6301 tcattcgtgt agttcgctgt acggatatgg attagcttcc aagctcttta aatgctccac
     6361 aatctcacac tcttccctcg tcaattcccg atccttccaa ccgtctatta ttgcatgtgc
     6421 ctccgccgcc agctcttcgt caaagacctc ggcgtaacaa gctaccaaca aacggcattt
     6481 caaaagcgaa gcgggaagtg tatccaagag atcccaacta cgattgagga ccgactggat
     6541 tttatcttcc ttatcaccgt gattataaat ggtagcatta tagccggtca acaaagcgat
     6601 acaaagagaa gcttcctctt cgagggtacg tccatgtgaa ccgaaaagat gctcacaacg
     6661 atgatacaca tccgtattca actgacggaa acggtcggag tagatgggtt cgccatccag
     6721 acctaaatgg agaagttcgt gcgaaacggc gcacaaagaa tcgatttctg attgcaaaga
     6781 caacatggtg atttatttac gtattggaat atgcaccaca gagggcacag agttcacaga
     6841 gtttttaatt ctttattaat tcgattaaag agggatgaat gaaggccgtg gcaactgcca
     6901 taaccccctg gatggaaacc accacacggc ggtcaccttt gatacggaca aactcaccct
     6961 caactccctc gaagatgcca ccggtgacac ggacacggtc tccctttttc atggaaacga
     7021 ctgaaggatc cagataaaca acctgttcat cgtaattacc ggcaacggcg ataaaactac
     7081 gcatttggac ttcaggaatg gtaataggct gacgggtctc acggtccatg atataacgaa
     7141 taggaagaga agccccgaca gtggatttca tttcgtcaac ctcactgcga gtggcataaa
     7201 caaaaaccaa gttgtgaaca acaggaacca atttacggat cttacgctca ccacggaata
     7261 cgtattcata gcgcatggga agaaaattcc tcactccgcg ggagtccagg tattccttaa
     7321 aggcaagctc acggctatag gtgatacgaa gggcgtacca ggatttatta atgctattgt
     7381 tcacaaaagg atataattgg gggacaccgg ggtagtgaaa caccttccgg tcaagtttgc
     7441 taattctgtt gtttgccttg cagcgtatat catttcatca ggtactcccc tatcgcagga
     7501 gagacagttt gaaaaagaag aacagaaaac gaagtttgaa aaaacagggc cttactgatc
     7561 ttacaatctg taaacgagtc tattatgaag cgaaagtgtt tcaaaagacg atcgtttaat
     7621 tgaacgcaaa gatagagggt attttcataa ctgcaaaaat gtttaataaa aaaaatgttt
     7681 tccttcatgg cttgatctat ttaattattt gataatcaaa tgtctataaa ctaacaaaaa
     7741 atggcttgat ctatttaatt atttgataat caaatgtcta taaactaaca aaaaacgctt
     7801 taatatctgt ctgcttttat atgtatttta attgtctgga tctttaaaaa
//
