LOCUS       gnlProkkaJLPOELPL_66    3720 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JLPOELPL_66.
ACCESSION   gnlProkkaJLPOELPL_66
VERSION     gnlProkkaJLPOELPL_66
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 01:59:09
            Original ID  :: gnl|Prokka|JLPOELPL_66
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3720
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3720
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[2:3561]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..3561
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..3720
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3720
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(3..962)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Fe-ADH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_1"
                     /sec_met_domain="Fe-ADH (E-value: 1.1e-73, bitscore: 236.8,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWSKKSNLSRYSSRKLFLVRGKKSYELCGAKRVVEDVISNLKCGF
                     VEYFDFSENPKYEDLERGLKLLELSGADLIVAIGGGSVLDMAKLIRFFHSYSGDILNEK
                     FVKNRDLLPLFAIPTTAGTGSEVTHFAVLYKDNLKYSVSHKDMLPDRAIICPQFTYKNA
                     RYLTACTGFDALSQAIEAYWNVYSIEESDNYSIKAIKLIWDNLPLVIDSSTNELRDKIA
                     EGAYWAGKAINITKTTAPHAFSYPFTINYGYPHGHAVALTFPFFMRYNYAELENKLHPL
                     LNSKSHCKKMEQLYNMLGSTFDMIYDDMYNYLERIGLAI"
     CDS             complement(1050..1175)
                     /locus_tag="ctg66_2"
                     /transl_table=11
                     /translation="MRKGARKDLGRPTLTPVKNKELLMNFLEEADESDKSDNVFK"
     CDS             complement(1202..2002)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 7.7e-20, bitscore:
                     59.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQNSGIGNTVNPLLSLTDKVVYNIPVLLLIGWRGEPGIKDEPQHI
                     KQGMITIPLLDTLGIKNQILNKDPNMAKSQINDAIEYMRMTKEAFAFVIQKDTFEEYKL
                     QNTEDSKFDLDREEAIKIVCNSLDKGSVIVSTTGMISRELFEYRESIDANHETDFLTVG
                     SMGHASQIALGIALRRKNKKVYCFDGDGAVLMHMGALTTIGTSRAVNYIHIVFNNGAHD
                     SVGGQPTVGLKVNLSKIASACGYNNVISVDSKATLKESLDSLKV"
     CDS             complement(2047..2211)
                     /locus_tag="ctg66_4"
                     /transl_table=11
                     /translation="MLSPKFFVETLQTYSMDFFTGVPDSLLKNMCAYITDHIESQNNII
                     AVNEELRLD"
     CDS             complement(2221..3561)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 203.8;
                     E-value: 5.5e-62)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_5"
                     /sec_met_domain="CTP_transf_like (E-value: 1.2e-16,
                     bitscore: 49.9, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 2.1e-119, bitscore:
                     386.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 9.3e-66, bitscore:
                     210.4, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNNKQVKKMDIEKKKTVYVGMSADIIHPGHLNIISEAQRLGKVT
                     VGVLTDAAIASYKRLPYLNYEQRSLIVKNIKGVDEVIPQTTLDYVPNLKLLKPDFVVHG
                     DDWKEGIQKETRQKVIDTIAKWGGKVIDIPYTKGISSTQLNEKLKEIGTTPEVRLKRLR
                     RLIEAKSVVRICESHSGLTGLIIENTVVEVNGVKREFDGMWSSSLTDSTSKGKPDIEAV
                     DLTTRLHDLNDALECTTKPIIFDGDTGGKIEHFVFTVRTLERLGVSAVIIEDKVGLKKN
                     SLFGTDAVQLQDTIEGFSEKIKAGKLAQITTDFMIIARIESFIAGKGLEDAIERALAYV
                     EAGADGIMIHSKDKSGEDIKKFCYAFRQLNKSIPIVVVPTTYNHITETELASWGVNVII
                     YANHLLRSAYPAMLNTAKIILANERSFEANDLCMSVREILELIPGTK"
     CDS             complement(3551..3676)
                     /locus_tag="ctg66_6"
                     /transl_table=11
                     /translation="MKNNKQVKKMDIEKKKTVYVGIIIVVQRHYEEIMKLIKNEK"
ORIGIN
        1 ttaatagcta agcctattct ttctaaataa ttatacatat catcataaat catatcaaaa
       61 gttgatccca gcatgttata taattgctcc atttttttac aatgactttt actattcaat
      121 aaaggatgca acttattttc taattctgca taattatatc tcataaaaaa aggaaatgtt
      181 aatgctactg catgtccatg agggtagcca tagtttatcg taaaaggata tgagaaagca
      241 tgaggcgctg tcgtttttgt tatattaata gccttaccag cccaataagc accttctgct
      301 atcttatctc ttaattcatt tgttgaggaa tcaatcacta aaggaaggtt atcccatatt
      361 aactttatag ctttaataga gtaattatca gattcttcaa ttgagtaaac attccaataa
      421 gcttcaatag cttgtgataa agcatcaaag ccggtacacg ctgtcaaata tcttgcattt
      481 ttatacgtaa actgaggaca aattatagcc ctatcaggca acatatcctt atgagaaacc
      541 gaatatttca aattatcctt atataaaaca gcaaaatgag tcacttcact accagttcct
      601 gctgtagttg gaattgcgaa taaaggtaat aaatctctat ttttaacaaa tttctcattt
      661 aatatatctc ctgaataaga atgaaaaaag cggattaatt tagccatatc taaaacactt
      721 ccaccaccta tggctactat taaatccgcc ccacttaatt ccagcaattt cagccctctc
      781 tccaaatcct catacttagg attttctgaa aaatcaaaat attcaacaaa cccacacttt
      841 aaattagaaa taacatcttc aacaactctt tttgctccac ataattcata agactttttg
      901 cccctaacga ggaataattt ccgagagcta tatctagata aattactctt tttgctccac
      961 ataattcata agactttttg cccctaacga ggaataattt ccgagagcta tatctagata
     1021 aattactctg taaatattca aatggatcat tatttaaaca cattatctga tttatctgat
     1081 tcatctgctt cttctaaaaa gttcattaat aattccttat ttttaacagg agtcaaagta
     1141 ggacgtccca aatcttttct tgcccctttt ctcactttta cctccaataa tacaggtcca
     1201 tttatacttt taaactatcc aaactttctt ttaaagtagc tttactatct acagatataa
     1261 cattattata accacaagca gaagcaattt tagagagatt gacctttaat cccactgttg
     1321 gttgcccacc aacagagtca tgcgcaccat tattaaacac gatatgaata taattcacag
     1381 ctctactagt tcctatggta gttaatgctc ccatatgcat aagtacagca ccatcaccat
     1441 cgaaacaata cacttttttg ttctttcttc ggagagctat acctaaagct atctgtgatg
     1501 catgccccat tgaccctact gttaaaaaat ccgtttcatg atttgcatca atagattccc
     1561 ggtattcaaa taattcccta gaaatcatcc cagtagttga aactataaca ctacctttat
     1621 ctaaagaatt acaaactatt ttaattgctt cttctcgatc caaatcaaat ttactatcct
     1681 ctgtattttg aagcttatat tcttcaaaag tatctttttg aatgacaaaa gcgaaagcct
     1741 cttttgtcat tctcatatat tctattgcat catttatttg actttttgcc atattaggat
     1801 ctttattaag aatttgattc tttataccaa gagtatccaa aagaggaata gtaatcatgc
     1861 cttgtttaat gtgttgtggt tcatctttta taccaggctc accacgccac cctatcaaca
     1921 acaatacagg aatgttataa acgactttat ccgtcaaaga caacaaaggg tttacggtat
     1981 taccaatacc tgaattttgc atatacacaa taggaataca ccctgtagca atataatatc
     2041 cggcagctag tccaagcgca gttcctcgtt cactgcaata atattatttt gagattctat
     2101 atgatctgta atataagcac acatattctt caataaagag tcaggaactc cagtaaaaaa
     2161 atccatagaa tatgtttgca acgtttctac gaaaaactta ggtgataaca taatttccaa
     2221 ctatttagta ccaggtatta attctaatat ttcccttaca gacatacata aatcatttgc
     2281 ttcaaacgaa cgttcattag ccaaaataat tttagcagta ttaagcattg caggataagc
     2341 actccgaagc agatgattag cataaataat aacatttact ccccaagaag ccaattctgt
     2401 ttccgtaata tgattataag ttgtaggcac gactacaatt ggtatagatt tattcagttg
     2461 cctaaatgca taacaaaatt ttttaatatc ttcccctgac ttatctttac tatgaatcat
     2521 tataccatct gctcctgctt ctacatacgc caaagctctc tctatagcat cctcaagccc
     2581 tttacccgca ataaaacttt caatgcgtgc aatgatcata aaatcagtag ttatttgagc
     2641 cagctttcca gcttttatct tctcagaaaa accttctatt gtatcttgaa gttgaacagc
     2701 atcagtacca aataacgaat ttttcttcaa cccaacttta tcttctatta taacagctga
     2761 aacacctaaa cgctctaatg tacgcacagt gaatacaaaa tgctctattt tcccccccgt
     2821 atcgccatca aatataatag gcttagttgt acactctaaa gcatcattta gatcatgaag
     2881 acgagtagtt aaatctacag cctctatatc aggcttaccc ttagatgtag aatcagtcag
     2941 actacttgac cacataccat cgaactcgcg ttttactcca tttacctcaa cgactgtgtt
     3001 ctcaattatc agccctgtca gcccactatg agattcacaa atacgtacaa cagacttagc
     3061 ttcaataaga cgtctcaacc tctttaaacg aacttcagga gttgtaccaa tttcctttag
     3121 cttttcatta agttgagtag aagatattcc tttagtataa ggaatatcaa tgacctttcc
     3181 tccccatttt gcaattgtat caataacttt ttgcctagtt tccttttgta taccttcttt
     3241 ccaatcatcg ccatgaacaa caaagtcagg ctttaacaat ttcaagttag gtacgtaatc
     3301 aagcgttgtc tgtggtataa cctcatccac tcccttaata tttttaacaa ttaaagagcg
     3361 ctgctcataa ttcaaataag gtaatcgttt gtaactagct atcgcagcat ctgttaaaac
     3421 tccgaccgtt accttaccta atctctgggc ttctgaaata atatttaagt gacctggatg
     3481 aataatgtca gcactcatcc caacatacac agttttcttc ttttctatat ccattttctt
     3541 tacttgtttg ttatttttca ttttttataa gtttcattat ttcttcataa tgtctttgta
     3601 caactattat tatcccaaca tacacagttt tcttcttttc tatatccatt ttctttactt
     3661 gtttgttatt tttcattttt tataagtttc attatttctt cataatgtct ttgtacaact
//
