LOCUS       c00002_gnlPro..        13974 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DDLHBMEM_2.
ACCESSION   c00002_gnlPro..
VERSION     c00002_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 20:36:51
            Original ID  :: gnl|Prokka|DDLHBMEM_2
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13974
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13974
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[460:3974]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      461..3974
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13974
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13974
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             69..353
                     /locus_tag="ctg2_1"
                     /transl_table=11
                     /translation="MCIYEYLYKEEVSKGIEIKIDDVVLVCALEHDKCNKSILYFNDVA
                     NIARYIHYCNSNFEYKEELNGWIMSDSYLALSISEDDYEKRFAFIQTLL"
     CDS             complement(461..1216)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_2"
                     /sec_met_domain="Fer4_7 (E-value: 5.6e-12, bitscore: 38.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 4e-25, bitscore: 80.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-06, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQAGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISERKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIPKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNISISNIARLNRDFIIAKLKD"
     CDS             complement(1253..3232)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 200.6; E-value:
                     1.5e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.9e-61, bitscore:
                     200.6, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 4.1e-36,
                     bitscore: 116.1, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLFTRYEMQDVVIIDGRARGIIAKNLITGELERFAAHA
                     VVIATGGYGNAYFLSTNAMGCNCTAAISCYRKGAVFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKKEDAIKLQKGEIKGSDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSEAINRLGIDVVLQRYGNLFDMYEEITDVNPGE
                     LAKEISGVKYYNPMMIYPAIHYTMGGIWVDYELQTTIKGLFAIGECNFSDHGANRLGAS
                     ALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAEAEKAVQAKIDKFMSIQGKES
                     VDSIHKKLGHIMWEYVGMGRTAEGLKKGIAELKAVRKEFETNLFIPGSKEGMNVELDKA
                     IRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDENFFYVACWEYQGDDE
                     KAPVLIKEPLVYEAIKVQTRNYKS"
     CDS             complement(3270..3974)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_4"
                     /sec_met_domain="SucD_FumR (E-value: 9.8e-131, bitscore:
                     425.5, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVAIISADGYNMI
                     CEFLGANWYALVATAALAALFIIHIIYAFWLTMQNRTARGSERYAVVDKPKTVEWASQN
                     MLVLGIIVIVGLGLHLFNFWAKMQLPELMHNLDMHADTLTLAYAANGAYHIQQTFSCPV
                     YVVLYLIWLFALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLGFALVVVV
                     FFVKSLLCGGAC"
     CDS             complement(4095..5045)
                     /locus_tag="ctg2_5"
                     /transl_table=11
                     /translation="MEERILFSQKTTIFVPVDNDSRIKPMSKDSLCAQHTDCSGCPKAM
                     ESTLIHRNLLRGQHIPKDKCTQNCMLFMIEGELLINSDEHPGTTLHEKQFILQAIGSKY
                     EILALTDVSYILFWFNELPLLCENRYREIIDQAEGPLTYTPMVMNPRLFYLINDVAAYL
                     DESTPACGKYIDLKCQEMVYMITNYYPLPQLRAFFYPISTYTESFQYFVMQNYSKAKNV
                     EEFAHLGGYNTTTFRRLFRNLYGVPVYEWMLEKKREGILEDLQHSNMRITEICNRYGFD
                     SLSHLAHFCKDSFGDTPRALRKKAANGEKIGKITD"
     CDS             complement(5729..6727)
                     /locus_tag="ctg2_6"
                     /transl_table=11
                     /translation="MKEQDGNQPFLMCCHFKATHEPYDYPIRMEHLYDGLTFPEPENLL
                     DWGPETNGRSFKGQTLEELERRWRIASQDPDKWWCRYPGLPFSTEGMQRTAARRASYQK
                     FIRDYLRCCATVDDNIGKLLNALDEMNIADNTIVIYVSDQGYFLGEHGFFDKRMFYEES
                     ARMPFVIRYPKKVPAGKRLDDLILNVDFAPTLAEFAGVKMENVQGDSFVSNLEGNTPTD
                     WRKEIYYRYWTNHAIRPAHFAIRSDRYKLIFYYARNLDMTDTENFDFTPSWDFYDLQND
                     PHENHNAYNDPKYAPVIKQMKKDLLRLRKETGDTDGKYPEMQELLEKYYNK"
     CDS             complement(6724..7311)
                     /locus_tag="ctg2_7"
                     /transl_table=11
                     /translation="LKKCNIYTYMNKLVLTGLLAAGTMTHLQGAQPAGQRPNILFILSD
                     DHTSQAWGIYGGVLAEYAHNANIRRLAKEGVVLDNCFCTNSISAPSRASILTGLYSHRN
                     RLYTLADSLDTSIPTLATLLQANGYHTGLVGKWHIQSQPQGFDYYSIFYDQGEYRDPTF
                     IESTDRGPATTSSANGCSASPPTSSPRKPSDG"
     CDS             complement(7498..7593)
                     /locus_tag="ctg2_8"
                     /transl_table=11
                     /translation="MGFDRKSRYRQRKQMFKNHYNTSKNQHKVSY"
     CDS             7609..8574
                     /locus_tag="ctg2_9"
                     /transl_table=11
                     /translation="MLLPRKIVFFLLLFVGLSLYAQQNCFISSYVRGNFYNRGRISAES
                     LRASDDLIFLNVRPNKDGSLSFENPRIFENGKGVTSWEELIKSVRADVKGTKTKLRLGA
                     ASGEWKAMVADEAARVAFAKNIKKILEKNKLDGIDLDFEWAETEKEYEDYSLAILKMRE
                     VLGDKYVFSVSLHPVCYKISKEAIAAVDFISYQCYGPSPVRFPMEKYCSDIQMALAYGI
                     PKEKLVAGVPFYGVTKDGSKKTEAYFSFVQDGLITGPAQNEVTYKGDVYVFDGQNNIRA
                     KTRYAMDQQLKGMMSWDLATDMPLNDSRSLFKTMVEELGR"
     CDS             complement(8543..8797)
                     /locus_tag="ctg2_10"
                     /transl_table=11
                     /translation="MSGSTLYRKMKALTGLSTNEYIRKVKMQNAERLLLEGKYNISEIA
                     YKIGMNSTGYFRQCFKDEFGVSPSDYLKQFTSPTPPPSS"
     CDS             complement(8794..12672)
                     /locus_tag="ctg2_11"
                     /transl_table=11
                     /translation="MKTYIAAFFLLLSATFVAAHPYLIQRLGIEQGLSNNYVLSITQDK
                     QGFLWFATEEGLNKFDGTRFITYYKEEQSSSVQSITGNELNEVYADPVQPVIWIATQRA
                     GLNAYNYETQSFSVYQYNPEDPQSLITNDVTHITSSVQAGKGLWVCTYYRGIEYLDIAT
                     GKFTHYNKSTVPALPSEQTWTATEAEDGKLYIGHVEGGLSILSLNDKSVKHFVHDPQNP
                     NSLPGNDVRCIYKDTNGNIWIGTSKGLALFNANTETFTNFHNNPGNIHGALSSYIFSIK
                     QLKDNKLWIATELNGIMILDLQQNQFLLPEQIRFEFIREGDNNYSLSNASARYIFQDSF
                     NNIWIGTWGGGINFISNAPPAFHTWSYSPTQMNESSLSNKVVSSVCDDGQGKLWIGTDG
                     GGINVFENGKRVAIYNKENRELLSNSVLCSLKDSEGNLWFGTYLGNISYYNTRLKKFQI
                     IELEKNQLLDVRVFYEDKNKKIWIGTHAGVFVVDLASKKVIHHYDTSNSQLLENFVRSI
                     AQDSEGRFWIGTFGGGVGIYTPDMQLVRKFNQYEGFCSNTINQIYRSSKGQMWLATGEG
                     LVCFPSARNFDYQVFQRKEGLPNTHIRAISEDKNGNIWASTNTGISCYITSKKCFYTYD
                     HSNNIPQGSFISGCVTKDHNGLIYFGSINGLCFFNPDIAINSPQIPPVVITKVRIPGRL
                     TSREKNETAIPISEGEIELTHEQNSFNLTFNVQDYSLANQVEYAYMLKGLENSWYTINE
                     QNSVTFRNIPPGKYEFLVKARLHNQDWSEDTTSLRIHINPPLWLTWWAKLIYILITISI
                     IYTIIHAYKKKIDLESLYTLEKKNHEQEQELNQERLRFYTNITHELRTPLTLILGPLED
                     MQKDTSLPTRQAQKLSVIHQSALRLLNLINQILEFRKTETQNKKLCVCKSNIAPLVHEI
                     GLKYKELNQKKAIDFQIQIEKEEMLLFFDKEIITIILDNLISNAIKYTEQGKITLSLYP
                     TTRNGVTYTEIKVSDTGYGISAEALPHVFDRYYQESGKHQASGTGIGLALVRNLVELHE
                     GEIRVESIQNEGSTFYISLLTDNIYPNALHGDSTKQTEEEMISEAVPEDSQNTEPETSK
                     PILLIVEDNEDIQKYIAESFSDSFEVITGSNGEEGKQQALNRIPDIIVSDIMMPVMDGI
                     TLCRQLKEDVRTSHIPVILLTAKDSLQDKEEGYEVGADSYLTKPFSASLLRSRINNLLD
                     SRKKLIAQFQQAGTNHNPNSHLDEKRSIITERSANWITNSLRKSRNWLRITFLRRRSTS
                     LICPTRCV"
ORIGIN
        1 tatatatagg tagaagcgta ttaaataata cgagcagtca cattcaaaaa ttattcttta
       61 aaaaagagat gtgtatatat gagtacttgt ataaggagga ggtaagtaaa ggcattgaaa
      121 ttaaaataga tgatgttgtc ttagtctgtg ctttagaaca tgataaatgc aataagtcca
      181 ttctttattt taatgacgta gcaaatatcg cacgttacat tcattactgt aacagtaatt
      241 ttgaatataa agaagaactc aatgggtgga tcatgtcaga tagttatctt gctttatcta
      301 tatctgagga tgattatgag aagcgatttg cgtttataca aactttacta tgaacttaac
      361 tgagtcgttt tattatactt ttgctaatga gtaaaaagaa aatcccccgc cagctaacgc
      421 cgacggggga tttatgctat taatcaaatc aagctcacgc ttagtctttc agtttagcga
      481 tgatgaagtc gcggttcagg cgggcgatgt tgctgataga gatgttcttc ggacattcag
      541 cctcgcaagc gcgggtgttg gtacagttac cgaatccgag ttcatccatc ttagacaaca
      601 tagctttcgc acggcgcaga gcttccggtt taccttgcgg aagcaagttc agctggctga
      661 cctttgcaga aacgaacaac atagcagaac cattcttaca agcagctaca caagcaccgc
      721 aaccgataca agaagcggca tccatagctt cgtcagcgat gggcttcggg atcaggatag
      781 cgttggcatc ctgcggagcg cctgtacgaa cgcttacata accaccggcc tgcatgatct
      841 tgtcataagc agtacggtct accatcaagt ccttgatgac agggaaaccg gccgaacgcc
      901 aaggctcaac agtgatggtg tcaccatcgt tgaaacgacg catgtaaatc tggcaagtag
      961 tagcacctgt tgcaggaccg tgcggatgtc cgttgatgta aagagaacac ataccgcaga
     1021 taccttcgcg gcagtcgtgg tcgaatacaa ccggttcttt tctttcgctg atcagctgtt
     1081 cgttcagaat atccagcatt tcgaggaagg aagtatcacc ggggatatct ttcatttggt
     1141 aggtttcaaa agcgccttta gccttcgggc ctgcttgacg ccataccttc agtgtaaatg
     1201 atatattttt atccattttc gtctaattct tttaaatgtt taacttcacc gattagctct
     1261 tgtagttacg ggtctgaacc ttgatagctt cgtataccag cggttctttg atcaatacag
     1321 gagccttttc atcgtcaccc tgatattccc agcaagctac gtagaagaag ttttcgtcat
     1381 cacgttttgc ttctccttct tcagtctggt attcttcacg gaagtgacca ccacaacttt
     1441 cgttacggtt caatgcgtcg taagcaacga gctcgcccat agtgatgaag tcatacagac
     1501 ggatagcctt gtcgagctca acgttcatac cttccttaga accggggata aacagattgg
     1561 tttcgaattc cttgcggact gctttcagtt cggcgatacc tttcttcagg ccttctgccg
     1621 tacgtcccat acctacgtat tcccacatga tgtgacccag tttcttgtgg atagaatcaa
     1681 ctgattcttt accctggatg ctcatgaact tgtcgatctt agcctgaact gccttttctg
     1741 cttcggcaaa ttccggaagg tcagtagaga aacgaggaac agtaatctga tctgccagat
     1801 agttctggat agtgtaaggc aatacgaagt aaccgtcggc cagaccttgc atcaatgcgg
     1861 aagcaccgag gcggtttgca ccgtggtcgg agaagttaca ttcaccgata gcgaacagac
     1921 ccttgatggt agtctgcagt tcgtagtcta cccagatacc acccattgtg tagtggatag
     1981 ccggataaat catcatcgga ttataatatt tcacaccact gatttctttt gccagttcgc
     2041 ccggattaac gtcagtgatt tcttcataca tatcgaagag gttaccataa cgctgaagca
     2101 ctacatcgat gcccaggcgg ttgatagctt cagagaaatc gaggaatacg gccagacctg
     2161 tgttgttcac accgaaacct gcgtcgcaac gttctttagc tgcacggctg gcaacgtcac
     2221 gtggaaccag gttaccgaat gccggataac ggcgttccag ataatagtcg cggtcttctt
     2281 caggaatatc gcttcccttg atttcgcctt tctgcaattt gatagcgtct tctttcttct
     2341 tcggaaccca gatacgaccg tcgttacgca gagattcgga catcagagtc agtttggact
     2401 gcttgtcacc gtgtaccggg atacaagtcg ggtgaatctg aacgtatgcg gggttagcga
     2461 atacagcacc cttgcggtag caagagatag cagctgtaca gttacaaccc atagcgttgg
     2521 tagacaggaa gtaagcgtta ccgtaaccac cggtagcgat tactacggcg tgagcagcga
     2581 aacgttccag ttcgccggtg attaagttct tggcgatgat accgcgagca cgtccgtcga
     2641 tgattacaac gtcctgcatt tcataacggg tgaacaactt caccgtacct acgtttacct
     2701 gacggcttag tgcggagtaa gcacccagca acagctgctg accggtctgg cctttagcgt
     2761 agaacgtacg tgatacctgt gcaccaccaa aagaacggtt gtccagtgta ccgccgtatt
     2821 cgcgtgcgaa aggaacaccc tgggctacgc attggtcgat gatagcgttg gatacttcgg
     2881 ccagacggta aacgttggct tcacgtgcac gatagtcacc accttttact gtatcgtaaa
     2941 acagacggta aacggagtca ccatcattct gataattctt tgcagcattg ataccaccct
     3001 gtgcagcgat agagtgtgca cggcgcggag agtcctgaat acagaagttg aatactctga
     3061 aacccatttc accgagggat gcagcagcag aagcacctgc cagacccgta cccacaacga
     3121 tgatatccaa acggcgttta ttagcggggt tcaccaattt ctggtgagct ttatagttgg
     3181 tccatttctc agccaccggg ccttctggaa tttttgaatc tatcttgatc ataatattat
     3241 ttacaattta atcatttaca atttactatt tagcaagcac cgccacaaag gagtgatttc
     3301 acgaagaata ccactactac gagtgcgaaa ccgagtacta caatcgtaga atagatgtta
     3361 gaaatacatt tccaacgatt gatccatacc ttgttgttcc atcccagtga ttgcatggag
     3421 ctccagaaac cgtgagtcag gtggaaccac aaagcaaaca gccaaatgag gtagagcact
     3481 acataaaccg gacaagagaa tgtctgctgg atgtgatatg caccgtttgc cgcataagcc
     3541 agcgtcagtg tatcagcgtg catgtccagg ttgtgcatca gttccggcaa ctgcattttt
     3601 gcccagaagt tgaagaggtg caaaccgagg cctacgataa cgataatgcc taacaccaac
     3661 atgttttgag aagcccactc tacagttttc ggtttgtcga ctactgcata gcgttcgcta
     3721 ccgcgcgctg tgcgattctg cattgtcagc cagaacgcgt agatgatgtg aataatgaaa
     3781 agagcagcca gtgctgcggt agctaccagc gcataccagt ttgctcccaa aaactcacaa
     3841 atcatgttgt aaccatcagc cgagatgatt gcaactaagt tcatcgccat gtgaaatgtt
     3901 agaaacagga caagggcgat accggtaacg ctcatcacca ctttccttcc tacagatgaa
     3961 ttacttaacc acataaatga ttgaatttaa attatttaat tgttagaact aaaatttcga
     4021 cgttttacac ctcttacaga ctgcaaaaat aggggaaata gattgattga ccaaagaatt
     4081 aaagaaataa ttccttaatc ggtgatcttt ccgatttttt cgccattggc cgctttcttg
     4141 cgcaaggcgc gcggggtgtc tccgaaggag tctttgcaga agtgtgcaag gtgggacagc
     4201 gagtcgaaac cataccggtt gcaaatctct gtaatccgca tattagagtg ctgtaggtct
     4261 tcgaggatgc cttcccgttt tttctccagc atccattcgt agacgggcac gccgtataag
     4321 tttcggaaga gacggcggaa ggtggtggtg ttatagcctc ccagatgtgc gaattcttcg
     4381 acgttcttcg ctttgctgta attctgcatg acaaagtatt ggaaactttc cgtataggtg
     4441 ctgatcgggt agaagaaagc cctcaactgg ggcaggggat agtaattggt gatcatatac
     4501 accatctcct gacatttcag gtcgatatat ttgccgcagg cgggtgtcga ttcgtcaagg
     4561 tatgcggcta cgtcgttgat gagatagaac aggcgcgggt tcatcaccat tggggtgtag
     4621 gtcagcgggc cttctgcctg gtcgatgatt tcacggtagc ggttttcgca tagcaacggc
     4681 agttcgttga accagaaaag gatgtatgat acgtccgtca gtgccagtat ctcgtatttt
     4741 gagccgatgg cttgcaggat aaactgtttc tcgtgtagtg tcgttccggg atgttcgtca
     4801 ctgttgatca gcaattcgcc ctcgatcata aagagcatgc agttttgcgt gcacttatcc
     4861 ttcggaatat gctgccctct gagcagattt ctgtgaataa gagtactttc catcgctttg
     4921 gggcatcctg agcaatctgt atgttgagca caaagtgagt cttttgacat gggttttatc
     4981 cgtgaatcgt tgtctacagg gacaaagata gtcgtttttt gtgaaaataa aattctttct
     5041 tccattatgt tttagcagaa acggggatat gattgtcttt attggttttg tttgcacaac
     5101 tttgaagttt cacggactcc tgaatggcgt tctttaatac attaatacat ttttatctgc
     5161 catctgcagc attttcttca tccctttaca tgatatattc agaacaagta gtttcatcat
     5221 tagttccacc tgttgaaacc aagtgtttca aggcatgaaa caaactgttt caagtaatga
     5281 aacttcttgg aacaactgtc gatttcgttc atatgacagc tcgattcaac tcacttgacc
     5341 gcataagttg ctctgattga cctgtccgtt cgaaaggtat tatttcattt ttcagtcaat
     5401 aatggatgac ttctcagctg ttaatacctg atttctcaat tattaatagc tgacatgaca
     5461 atcgttaata gctgacgcgt cagatgttaa tacccagtaa atcaaagtat aatgtaggat
     5521 aaacgaccta tatgccgtgg tggcagagtg agagcaaacc cttgctctca ctctgccacc
     5581 atacttgctg taatgcttga aatgccgatg aataaaggga tacacgcgaa taatgagagc
     5641 gttagggcaa aactgctatc tttttcactt gtagcagctg cctaagttca agttataaat
     5701 gcgacagttc agtttccgta ccagtcactt acttattata gtatttttca agcagttcct
     5761 gcatttccgg atatttcccg tccgtatctc cggtttcttt gcgaagtctc aataagtctt
     5821 tcttcatctg tttgatgaca ggtgcatatt tcggatcgtt gtatgcatta tgattctcgt
     5881 gcggatcatt ctgtaagtca tagaagtccc atgacggagt aaagtcaaag ttctccgtat
     5941 cagtcatgtc tagatttcgg gcataataga agatcagctt gtaacggtct gaccggatgg
     6001 cgaagtgcgc gggacgaata gcatgattgg tccagtagcg atagtagatt tcttttcgcc
     6061 agtcggtcgg cgtgttgcct tccaggttgc tgacgaagct gtctccttgc acattctcca
     6121 tctttactcc ggcaaattct gccagcgtcg gtgcgaaatc gacattcagt atcagatcgt
     6181 ccagacgttt tcctgcgggt accttcttcg gataacggat aacgaaaggc atacgagccg
     6241 attcttcata aaacatccgt ttgtcgaaga agccgtgttc gcctaggaaa tagccttggt
     6301 cggagacgta gatgacgatg gtattgtcgg cgatattcat ttcgtccaga gcgtttagga
     6361 gtttgccgat gttgtcgtcg acggtagcgc agcaacggag gtagtcacgg ataaactttt
     6421 ggtaggaagc acgtctggcg gccgtccgtt gcatcccttc ggtgctgaac ggcagtccgg
     6481 ggtagcgaca ccaccacttg tcggggtcct gtgatgcgat gcgccagcgg cgttccagct
     6541 cttccagtgt ctgtcctttg aaagaacggc cgttggtttc cggtccccag tccagcaggt
     6601 tttcgggttc ggggaaggtg aggccgtcgt agagatgctc catgcgtatc gggtagtcgt
     6661 agggttcgtg cgttgctttg aaatggcagc acatcaggaa gggttggttg ccgtcctgct
     6721 ctttcatcca tcggatggct ttctcggtga cgaggtcggt ggagaagccg agcacccgtt
     6781 cgccgaactg gtggttgccg ggccacggtc ggtgctctct atgaaagtcg ggtcacggta
     6841 ttcgccttga tcgtagaaga tggagtagta gtcgaatcct tgcggttgcg actggatatg
     6901 ccatttgccg acgagtccgg tgtggtatcc gttggcttgt agcagggtgg caagggtggg
     6961 gatggaggtg tccagtgagt ccgcaagggt gtacagtctg ttccggtgac tgtatagacc
     7021 ggtgaggata ctggcacggc tgggtgctga gatagagttg gtgcagaaac agttgtcgag
     7081 cactacccct tcttttgcca gccggcggat gttggcgttg tgggcatatt ctgccagtac
     7141 tccgccatag atgccccagg cttgggaggt gtggtcgtca ctcaggataa aaaggatgtt
     7201 ggggcgttgt ccggcaggtt gagcgccttg caggtgcgtc atggttccgg ctgccagcag
     7261 accggtaagt acgagtttat tcatatacgt atagatgttg catttcttca aaagtcagtc
     7321 taagttagac ggttgctttc atgtagataa atgatcatat gaactgattt tatgcctaaa
     7381 gatagtgatt gttattcact ttgtattata atccggaaaa cttttgcgat ttaatgtaat
     7441 tgattccggt aaaacactta attccctttt taaaaggatg tttttgtttt acatctctca
     7501 ataagaaact ttatgttgat ttttggaagt attatagtga tttttgaaca tttgttttct
     7561 ttgcctgtac ctacttttgc gatcaaaacc cattaattat caattattat gctactacca
     7621 agaaaaattg tatttttcct tctcttgttt gtcggattat cgttgtatgc gcaacaaaac
     7681 tgcttcatta gttcgtatgt acggggtaat ttctacaatc gcggacgtat ttctgccgag
     7741 agtttaaggg cgagtgatga tctgattttt ctgaacgtcc gtcccaataa agatgggtcg
     7801 ctttcgtttg agaatccccg tatctttgag aatgggaaag gagtgactag ttgggaggaa
     7861 ttgataaagt ctgtccgtgc ggatgtgaaa ggaacaaaga caaaacttcg tctgggcgct
     7921 gccagtggcg agtggaaagc gatggttgca gatgaggcgg cccgtgttgc atttgccaaa
     7981 aacataaaga agatactgga aaagaataag ctcgatggca tcgatctgga ttttgaatgg
     8041 gcggagactg aaaaagagta tgaagattac agtctggcta ttctgaagat gagagaggta
     8101 ttgggagata aatatgtgtt cagcgtatcc ctgcatcctg tgtgttataa gattagtaaa
     8161 gaggcgattg ctgcggtcga tttcatttct tatcagtgtt acggtccttc gccggttcgc
     8221 ttcccgatgg agaaatactg ttcggatata cagatggcgt tggcttatgg cattccaaag
     8281 gaaaagctgg tggcaggcgt tcctttctat ggcgtgacaa aagatggctc aaagaagact
     8341 gaggcttact tcagttttgt gcaggacggg ctgattacgg ggccggcaca aaacgaagta
     8401 acctataaag gagacgtgta tgtctttgac gggcaaaata atatccgtgc caagacacgt
     8461 tatgcgatgg accagcagct caaaggaatg atgagctggg acttggctac ggatatgccg
     8521 ctgaatgaca gcagatcgtt gtttaagacg atggtggagg agttggggag gtgaactgct
     8581 tcagataatc tgaaggagag acaccaaact catccttaaa acattgacgg aagtagcctg
     8641 tactgttcat tcctatttta taggctattt ccgagatatt atattttcct tcgaggagta
     8701 accgttccgc attctgcatt tttactttcc ggatgtactc gttcgtagaa agtccggtca
     8761 gtgctttcat tttccggtag agcgtagaac cgctcataca catcttgtcg gacagataag
     8821 tgatgtcgat cttctccgaa gaaaggttat cctcaaccag ttgcgtgatt ttctcaatga
     8881 attcgttatc cagtttgctg agcgctcggt gattatggaa cgcttttcat ccaaatgaga
     8941 attggggtta tgattcgttc cggcctgctg gaattgagca atcagtttct ttctcgaatc
     9001 aagcagattg ttgatgcggc ttcgcagcag tgaagcactg aaaggcttgg tcagataaga
     9061 atccgctccc acttcgtatc cttcttcttt atcctgcaat gaatctttgg ccgttagcag
     9121 gatgacaggg atgtggctgg tacgcacatc ctcttttagt tgacggcata gcgtgatgcc
     9181 atccattacc ggcatcatga tatcgcttac tataatatcg ggaatacggt tgagagcctg
     9241 ctgtttccct tcctcaccgt tgctgcctgt gattacttcg aaagagtcgg agaaagattc
     9301 ggcgatgtat ttctgtatat cttcattgtc ttctacaatc agcaggatag gtttgctcgt
     9361 ttccggttcc gtattttgag aatcttccgg aacagcttct gatatcattt cctcctctgt
     9421 ttgcttcgta gagtctccat gcaaagcgtt ggggtagata ttgtctgtta ataagctgat
     9481 atagaaagta cttccttcgt tctgtatgct ttccacccgg atttcgcctt cgtgcagttc
     9541 tacaagattt cggactaaag ccagtccgat acctgtgccg gatgcctgat gcttgccgct
     9601 ttcctgatag taacggtcga aaacatgagg caaggcttcc gcagagattc cgtatcccgt
     9661 atcactgact ttaatctccg tataagtgac tccgtttcgt gtggtgggat acaagctcaa
     9721 ggttattttt ccctgttccg tatatttgat ggcattggaa atcagattat cgaggataat
     9781 ggtgatgatt tctttgtcaa agaacagaag catctcttct ttttctattt gaatctgaaa
     9841 gtcgatcgct ttcttttgat tgagttcttt gtatttgagt ccgatttcat gaacgagggg
     9901 cgcgatgttg cttttgcaaa cacatagctt tttgttctgc gtttccgttt tccggaactc
     9961 aagaatctga ttgatcaggt tgagcagccg gagggcactc tggtggatga cagaaagttt
    10021 ctgcgcctgt ctggtcggca gtgacgtgtc tttctgcata tcttccagcg gaccgaggat
    10081 cagggtcagt ggtgtgcgca gctcatgagt gatgttagta tagaatcgca aacgttcctg
    10141 attcaattct tgttcttgtt cgtggttttt cttttccagg gtatagagac tttcgaggtc
    10201 tattttcttc ttataggcat ggataatagt ataaataatg ctgatagtga tcagaatata
    10261 aataagtttt gcccaccatg tcagccagag aggagggtta atatgtatcc tgagagatgt
    10321 cgtgtcctcc gaccagtcct gattgtgcag gcgggctttt accagaaact catacttgcc
    10381 gggaggaata ttgcggaagg tgacgctgtt ttgctcgttg atcgtatacc atgagttttc
    10441 aagtcctttc agcatatagg catattccac ttggttggcc agtgaatagt cctgtacgtt
    10501 gaaagtaaga ttaaaactat tttgttcatg agtcaattct atctctcctt cggagatggg
    10561 aatagcggtt tcgttcttct cccgacttgt gagtcgtccg ggaattctca ctttagtgat
    10621 aaccacagga ggaatctgcg gactgtttat ggcaatatcg gggttgaaga aacacaatcc
    10681 gttgatagag ccgaaataga tgagcccgtt atgatctttg gtaacgcatc cgctgatgaa
    10741 acttccttgt gggatgttgt tggagtgatc gtaggtatag aaacattttt tagaggtgat
    10801 atagcaactg atgccggtat tggtacttgc ccagatgttg ccgttcttat cttcactgat
    10861 agctcttatg tgtgtattgg gcagtccttc ttttctttga aaaacctgat agtcaaaatt
    10921 acgggccgaa ggaaaacata ccagcccctc accggtggca agccacatct gacctttgct
    10981 gctccggtat atctgattaa tcgtattgga acaaaaacct tcgtattggt tgaacttcct
    11041 gaccagttgc atatccggcg tatatatccc gactcctcct ccgaaagttc ctatccagaa
    11101 acgtccttca ctgtcttggg caatgctgcg tacaaagttt tccagcaact ggctgttgga
    11161 ggtgtcataa tgatgaatca ccttcttgct ggcaaggtct acaacgaaca cccctgcgtg
    11221 agttcctatc catatctttt tattcttgtc ttcatagaag acgcgtacgt cgagaagctg
    11281 attcttttcc agttcgatga tctgaaactt cttcagtctt gtattgtaat agctgatgtt
    11341 gcccagatag gtgccgaacc ataggttgcc ttccgagtct ttcagcgaac aaagcactga
    11401 gttggacagg agttctctgt tttctttatt gtaaatggcc acccgttttc cgttttcgaa
    11461 tacgttaata cctcctccgt cagttcctat ccacaatttt ccttgtccgt catcgcagac
    11521 gctgctaacg actttgttgc tcagcgaact ttcattcatt tgggtgggtg aatagctcca
    11581 tgtatggaat gcgggaggag cattgctgat aaaattgatt cctcctcccc aagtccctat
    11641 ccagatatta ttaaaagagt cttgaaagat ataccgtgcg ctggcgttgg acaaactgta
    11701 gttattgtcc ccttcgcgga taaactcaaa gcgtatttgt tcgggcagca gaaactgatt
    11761 ttgctgtaag tccagtatca tgattccgtt cagttctgtt gcaatccaga gtttgttgtc
    11821 tttgagttgt ttgatggaga agatatagct tgacaatgct ccgtgaatat tccccgggtt
    11881 gttatgaaag ttggtaaatg tttctgtatt ggcattgaac agggctagtc ctttgctggt
    11941 tccgatccat atatttccgt tggtatcttt atagatacaa cgcacatcgt tccccggaag
    12001 gctgttcggg ttttgaggat catggacgaa gtgcttcacg gatttgtcat tcagggagag
    12061 gatgctcaac ccgccttcta cgtgtccgat gtatagtttg ccatcctcag cctccgtggc
    12121 tgtccaggtc tgctcagagg gaagggcggg tactgtgctt ttgttataat gagtgaattt
    12181 cccggtagcg atgtccagat actctatacc tctgtaataa gtacataccc ataacccttt
    12241 gccggcttgt acggatgagg taatgtgagt gacatcgttc gttatcagac tttgcgggtc
    12301 ttccggatta tattggtaga cgctgaaact ttgtgtctcg taattataag cgttgagtcc
    12361 tgcccgctgg gtggctatcc agataacagg ctgcacggga tcggcgtaca cttcattgag
    12421 ttcgttgccg gtaatgcttt gaacagaaga agattgctcc tctttatagt aggtgataaa
    12481 gcgggttccg tcaaacttat tcagcccttc ttcggtggcg aaccacagaa atccctgctt
    12541 gtcctgcgtg atactcaata cataattgtt ggataagcct tgttctattc ccaatctttg
    12601 gatgaggtaa gggtgggctg ccacaaatgt ggcggatagc aggaggaaga aagccgcaat
    12661 gtatgttttc atcgtttcag atattatgta ttccttgata ttcactctca aaagtacaaa
    12721 taaatcttgt atttagtata gacaaatgat tcattgcatg attttctacc ctttctgcat
    12781 gatttttaca gcgaataaaa taaaacaact gtaattttgc aatcaatcaa ataaccgaat
    12841 ctaatacttg cagaaaatgg aatctgattc tttacacgaa catgataaaa gctggaaggc
    12901 attttttatt accactctgt tcatcttgtg tacagcgaac gtttatgcgc agtcatccga
    12961 tacaatcttt tcccgatatt tccgttatgc gcagaacttc gcagatgcgt accctcgcga
    13021 gaaagtgagt cttcatttgg ataatgcaag ttattacctt ggtgatacga tttggttcaa
    13081 agcgtatgta gtgacggctg aacaaaactt accgacgacg atcagcaaac ctttgtatgt
    13141 agaattactg gaccagttgg gaaatgtcgt agagcggcaa attattcagc ttacggatgg
    13201 ggagggaacg ggacaaatca ttttgaacaa taccttcttt accggttatt atgaaatgcg
    13261 tgcctataca aagtggatgc ttgcttttga taacccttcc tgtttttccc gtgtattacc
    13321 cgtctatcgg aaacggctga gcgatgaaga gactcctcgg agtatagcta cctatcgtat
    13381 ggacgcttcg atgaaacaga ggccgaagga taaagagaag aagtttacag tccgcttttt
    13441 tccggagggt ggacaactgg ttaaaggcat atcttcgatt gtagcttttg aagccaccag
    13501 ccgtgacaaa ggagctgctg atgtagaggg aacagtggtt ttgccgagtg gtgaagaact
    13561 ggcgcatatc cgttcattgc atgacgggat gggttacttt gagtataagc ccgaagaaaa
    13621 ggcgggtgtg gcaaaaattg attatgaagg ctccacttat cagtttgacc ttccggaagc
    13681 tcttccacaa ggatatgtac tccgaatcga taaccggcgg gaaatgttgg atatcactgt
    13741 agcccgcagt tcacaggcaa tgaaagacac actggctgtt tttgtatctt ctcaggggcg
    13801 accttacaaa tgtatgacac tggactttga agatgaattg aactgccaat tccggatttc
    13861 gactaaagaa ctaccgcccg gagtgcaaca gatatctctg gtcaatctga aaggggaaac
    13921 gttatgcgag cgtttttgtt atgtgatgcc gcgttcttcc atgctccttg cctg
//
