LOCUS       c00036_gnlPro..        16585 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JIBPMDEH_59.
ACCESSION   c00036_gnlPro..
VERSION     c00036_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 23:14:42
            Original ID  :: gnl|Prokka|JIBPMDEH_59
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 22538
            Orig. end    :: 39123
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16585
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[32538:35518]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12980
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16585
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16585
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(458..1102)
                     /locus_tag="ctg36_31"
                     /transl_table=11
                     /translation="MEDLSKLTSKDLEALLAKKREEEHRQALDKRAAYEGIRAELVQKV
                     ENKVRSVCDEVKGLHAFCVDEIGAFRQVLAEYGQLRREGQMSFTVQEGCFRIEVRSNKV
                     KRFDERADIAASRLIEFLQQWIEGKDAGSDDPMYQLAMTLLERNKYGDLDYKSISKLYE
                     LEDKFDDPEYTAIMNLFKESHLVEGTATNFYFFEKDKMGVWKKLEPSFNRL"
     CDS             complement(1121..1372)
                     /locus_tag="ctg36_32"
                     /transl_table=11
                     /translation="MGYIPIKDKLEEIERRGRQIRRRQEKLKDDAAFLADMLLTRATSD
                     MEAQRRLLREWEEEIEQLEQSLTFLRSEYMKYKHKSNS"
     CDS             complement(1379..1873)
                     /locus_tag="ctg36_33"
                     /transl_table=11
                     /translation="MATTKRQTKKHSHALFWTLLKETPGYDPCYKEVIKEGIVHEHSGG
                     RTTSLNEMYENYPSEYSRMIDAMKPKGEKKLMAYEERRDLSAKRVIAAICQWVDKLGYK
                     FRDDRHKLMYVKGIACRAANCGNFNAIPDDKLTAIYNLYCKRNSVGIEGNPELDHPVGK
                     N"
     CDS             complement(1893..2531)
                     /locus_tag="ctg36_34"
                     /transl_table=11
                     /translation="MGKILGVKQFLQERKKAMDFSGAFYHLLGRPEPQGAWIIWGQSGS
                     GKTTFTCRLAKYLAEFGRVAYLSLEEGDSLSLQRSFQDAGMMEVNGRVVLLDMNFDEMV
                     EKLAKPKSWDIVIIDSLQYARIDYDTYRDLRSRFPRKLFIFISHADGKNPKGGVADSIR
                     YDCSCKIYVEGFRAVAASRYLDHGQKSHPFIIWEEKAVLYYGQDFDQVK"
     CDS             complement(2534..3466)
                     /locus_tag="ctg36_35"
                     /transl_table=11
                     /translation="MNRNGLLKHVGDWITRLGSQSKVAEKCGISGTALSQWMNGKYGAN
                     SAELEKRIASTLGYQEDGWQVVTTIQNYRKIEFVYRSCKQQALWMAISNKAGSGKTQTL
                     EHLFNQDLTGSVVFIQAEEWNSRQFLVELAERTCGVPKRGYTDIPTLLKMIAEYFNGMA
                     GDHPVLIIDEADKLKPAAFRKLIPLYNRTEHRLGCVLAGTENLHKEIARGVRNNTKGYD
                     EIDSRLGRSYIELPGATEQDVKEICTANGLDDATADRIWNEVDKIKRYVKVTNKRGETK
                     EKNLFFCEDLRRLMRLVKREQIANQFGQM"
     CDS             complement(3491..5566)
                     /locus_tag="ctg36_36"
                     /transl_table=11
                     /translation="MEFYKNQLCISYTELTAGDPLAVDPLKRPILSESNFKYYKKTGKL
                     QVLNRACYGTPALVLYASLPDCVKQEVEARKGETFETEPKRYVLKEMIRRDPMAEQFFR
                     GWTFEGRPYDHLKPEYVELYVANASALNAVLELTGNRSLFIKQYGKPYNRVWPETSREL
                     NEIQDVVGCRLPKNHLALKRVALKYSEEGYESLISGKMKNNNARKNKESRQEALIVELI
                     GDGRNIDNETVARLYNAVAGRMNWKPITGATVANYRKEHPECYAGRYGKSALANNKLMQ
                     VTRTAPTAPMYFWCVDGWDTELFYQAHATDSRGRSVTTYHHRPTVVAIVDPFNKYIIGY
                     AIGRHESAALIRQAFRNAFEHVKELFGSYFKPWQVQTDNYGRGHLKCFYEAVGHWYTPA
                     AVKNAKSKIIEPFFNQFNRQWLRLLPNSSGHGVKSRQKLQVSDDWIETHKRDFPDFEGC
                     CQQLVKMIDFDRATKREEYINRWIDLPETDRQLFAPEDFLLAFGETAAPRPLRGDGVHL
                     QVGGHRFQYECFDKEFRSYGHTTFFLKYDPSDMDRVIAVENIGTQKEPKEGGVRFVLER
                     KYEQPMALKDREEGDAEQLHRVFNFNKEYVDDIVLKRTRSGEIVRELFEENEDLSNTLT
                     AHVITDSLGRHKDVRNEVAGRKEPIFLLRVPKQEEITNEEDDFTFSDDHSDFLNDF"
     CDS             complement(5739..5975)
                     /locus_tag="ctg36_37"
                     /transl_table=11
                     /translation="MKAKVILYGWALSWLSLFAGIGTMEHGSMLTGSLLCSVWFFFSYM
                     LIGNEAACKREVVRFEEWMVRLLGGSDKDKQSV"
     CDS             complement(5988..6362)
                     /locus_tag="ctg36_38"
                     /transl_table=11
                     /translation="METKRIDYKALCEAPFEMESLYEDNFPMLVYTGRKEEERPVFRVV
                     FAKGACKVVIGQQGKEFWGIIGLDPKTGETQWYNYNDCVSLENWAVLDRLLKTRFGWME
                     LTDPALVIETKMLAKAQLGN"
     CDS             complement(6477..7145)
                     /locus_tag="ctg36_39"
                     /transl_table=11
                     /translation="MGNKLQLFYNEEANVTIRTQQLNNEPWFVAKDVANALDIAWSGAT
                     LSNIPDDWKGMMSFNTPSSGDRGGGVQQLSVINEAALYKLAFRSNKPQADAFVNWVAGE
                     VLPQLRQTGQYRIKGEAECMREQQQRQRLPLPKYRPFFEEWKQRVKPYISRNELAEVAE
                     GIDVSYPHVRKVYAGTSVSEDVVRRITSLAKQNRSQGITYPDPVPICEQMCIEWDKEKS
                     "
     CDS             complement(7157..7381)
                     /locus_tag="ctg36_40"
                     /transl_table=11
                     /translation="MEEKRNEITVTLVLQREIAKKLAVTERTVQSALRFETNSPSAKLI
                     RAYALNHGGKMFEITKKEVDNPYKEVTII"
     CDS             7504..8310
                     /locus_tag="ctg36_41"
                     /transl_table=11
                     /translation="MKTILQRIEQIAINEGIKITTFEKSIGASKGVLSRAINNGTDIQS
                     KWLQSIVENYPRYSEAWLLTGRGSMLKEEPKSSQVDCEPSVYANTDLVRIPVVDISVAA
                     GSGFCNTDYIEEVESISMPSSMVKDGKQYLCVRVKGHSMVPSILDGGYLIIRKIERSEW
                     EGIRDNYVYVVSDTEGRSYVKRLKNRLRQHGFIVCMSDNADKQNYPNFNLYEEELNTIW
                     YAEWYFSAKIPNIQEVYYRKQGELEDRLDELTAQFQQFQKALNNNN"
     CDS             8312..8575
                     /locus_tag="ctg36_42"
                     /transl_table=11
                     /translation="MRTVDLNEISEFEKEFRRLRFNPIYFYEYYWKEKHPDEPELTREQ
                     KQKLYDEYRGTPFFQDFGEAIKHQERIKELKAQGYEDWEIMG"
     CDS             complement(8588..8767)
                     /locus_tag="ctg36_43"
                     /transl_table=11
                     /translation="MIISCLISKIKEWKEKRLRKKIILRLLVNRNHNPDGNRTAFEADN
                     IIRYIKSGLPYSVE"
     CDS             complement(9163..9369)
                     /locus_tag="ctg36_44"
                     /transl_table=11
                     /translation="MTKVIHVHLIFEKKNYYFGSISAIFNTLTEEEIGITKSSLLHAGM
                     TDGSCKVTKRAMIIQSHLIRGGK"
     CDS             complement(9373..9585)
                     /locus_tag="ctg36_45"
                     /transl_table=11
                     /translation="MPCNPPDLGAVKWLLELVQWFECRHQKEALNGLLFLLSDGRCLVD
                     ERKNILFKNFQIIIIWYICSIKHSK"
     CDS             9777..9998
                     /locus_tag="ctg36_46"
                     /transl_table=11
                     /translation="MTFRFAPYINNSTYQVEYLFEHEGCKVYRFMDMGHYIYFTNCEGD
                     VTSIESDSVRTVNRISRKPIIIKEQTLD"
     CDS             complement(10001..10384)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_47"
                     /sec_met_domain="Radical_SAM (E-value: 2.7e-08, bitscore:
                     26.1, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LEVLEQVDLVLLDIKTIDAGLHPRLTAVKLDNTLRFLDELEKRGI
                     PVWIRHVIVPGLTDDDEALSKLAEYISSYNVVQKAELLPYHTMGAYKYEAQGLDYKLKG
                     VEPLSAERLANAKAIFSKHGITV"
     CDS             complement(10740..12980)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_48"
                     /sec_met_domain="Gly_radical (E-value: 3.4e-45, bitscore:
                     144.7, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 1.4e-281, bitscore:
                     926.7, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFENENWAQFKGETWKKEINVRDFIQNNYKPYNGDDTFLVPSSE
                     KTKKVWNKLTEMFKVEREKGVYDAETKLPQGIDTYGPGYIDKENEVIVGLQTDAPLKRG
                     IFPKGGIRMVENSLEAYGYHLDPMTKEIFTKYRKTHNEGVFSAYTDEMIAARRSAIITG
                     LPDAYGRGRIIGDYRRVPLYGTQILIEEKKRFQKRLDIQELTEEIIQSREEITEQIKAL
                     KAFEKMCAGYGFDVTRPAKDAREAVQFLYLAYLAAVKDQDGAAMSLGRTSTFLDIYIEK
                     DICEGKLTEEEAQELIDQFIIKLRIVRFLRTPEYNDLFSGDPVWVTESLGGQGVDGRSL
                     VTKTSYRYLHTLYNLGPAPEPNLTVLWFNNAPDNWKNFCAKVSIDTSAIQYENDDLMRP
                     DYGDDYGIACCVSPMKIGKQMQYFGARANLAKCLLYAINGGRDEKSGVQVAPRFEPITS
                     EYLDYNEVMEKYEQMMRWLAKVYVNALKIIHYMHDKYAYEAFEMGLHDGDVERIRATGI
                     AGLSIVADSLAAIRDTKVKVIRDERGLAVDFEREGEYVPFGNNDDRTDSIAVDITEKFM
                     EYLRQHQTYRKATPTQSILTITSNVVYGKKTGTTPDGRPGGTPFAPGANPMNGRDTKGA
                     VAALASVAKLPFQHAHDGISYTFAVSPATLGKERDIQVNNLVSLLDGYFTPDGGQHLNV
                     NVFDKDLLLDAMEHPEKYPQLTIRVSGYAVNFVKLTREQQLDVISRTINSSL"
     CDS             complement(13408..15897)
                     /locus_tag="ctg36_49"
                     /transl_table=11
                     /translation="LYLYKLKTQELVDQVAVEAMNETMAGEGFNFDFTPKKKLDWANDV
                     LSDVKLKAFYVDNDFDLGNDMKIPAGVYFATSYPEELVGTDKIADSDLFKQCTFIAIDP
                     TGNYDINATDRDNGLGYELITMQGSEMNFFHGAATSDNFSHAEEVFVGNACFVVEVPNA
                     VTAPETYNIKAKNIHVFVTATDNAAKKHVAKAGLYIGCIADQNKNYMVTTVVTDALAFT
                     TTNTTLLDGDGLVGFLQEEDAPSVYTIQFVSGEKNEGASEYEQYLTVNKPAGFELASTV
                     DFNEADPMYQFVVTGVDKTNKTITLANRQTKVDFTVSLYENEDGVYTVLPATGSKDKVY
                     VEYINGTVGNNSKDEVVTFEAIDLTNMKIVLTPYTVEDKFATFVNRADNMGLVQFELAL
                     NSDIAPAFYVGGEKDVDGNLAPNKDILAYADADSMVQFELIKSKKPVNVLNNYIYLDGK
                     RIRTSTERDTVAFYTYAVKAFDDANDRYLSNTWELEVATDVSADEFIIKQNLDGSVSLI
                     KAATTTDVNGAFAMVNDLKKDRETAWKDAYNYELEHKIDKGLKTFMVDETPAVSLEAVP
                     QHVSFALTRGGFLTNKDNDAFQSIATEASEDLTFWVDTVKSDKNIPTFYISKAGHFLYN
                     AEDSVEYYEARGNYRFNLENQKGEAAKLIFNAGELVSSDTLRTVVDGKSVLVAEKDNAP
                     KKIKGGLDNFQFQIIKAEDGSDEYVIRQGRANYVQMINSYFYLEANKNTAVRFLIESQS
                     TPTANEGVAVSEVKVLAGEGNVTIAGAAGKKVVISNILGQVVANTVISSDNAVIAAPAG
                     VVVVAVEGEAAVKAIVK"
     CDS             complement(15957..16064)
                     /locus_tag="ctg36_50"
                     /transl_table=11
                     /translation="MRLIICILNSQCCLMILQAAFCKVQDCIPMQEGQG"
ORIGIN
        1 tagtccaact gttgtgcctc ccagttgatg ccggggcggt tccgatagag gttacggatc
       61 agccgtcggc actcttcggg catgaggcct gagttgagct tcgccatcgg gaggttgata
      121 cggtcgagtg tgatggtcga ggcttgcaag attttcgcat tgcctttcca tatacccttc
      181 aaatagattt gcttcactgc cccgatggca ttcctgaccg gatgatgcag acggatcgtc
      241 gtgaaacagc ggcagttcaa cttgccattg aagttctctt caaattccaa tcgttcgtcc
      301 atgactttgt aatattttcc tgtttgttgt ttgcatttaa aacaatagac catccacttg
      361 ctcgaagtcc tcaccacccg gcagacggtg tacctgaaac cacaggggca gacgtatatc
      421 cagcgaccgg gggtgagggt agtggatttt acccgtttta cagtcggttg aacgatggtt
      481 cgagtttctt ccatacgccc atcttgtctt tctcgaagaa atagaagttg gtcgccgtcc
      541 cttcgaccag gtgtgactcc ttgaaaaggt tcatgatcgc ggtatattcg ggatcatcga
      601 acttatcttc caactcgtag agtttcgaga tcgacttata gtcgagatca ccatacttgt
      661 tgcgctccaa aagcgtcatt gccaactggt acatcgggtc atcgcttccg gcatccttac
      721 cctcgatcca ctgctgcagg aactcgatca ggcgcgaagc ggcgatatcg gcacgctcat
      781 caaaacgttt cactttgttc gatctcactt cgatacggaa gcaaccctcc tggacggtga
      841 acgacatctg tccctcgcgg cgcaactggc cgtactcggc gagcacttgg cggaacgctc
      901 cgatttcatc cacgcaaaaa gcgtgcagcc ctttcacttc gtcgcacacg gaacgcactt
      961 tgttttcaac tttctgtact aattcagcac ggatgccttc ataggcggcg cgtttgtcca
     1021 acgcctggcg gtgttcttct tctctctttt ttgccaataa tgcttctaaa tctttacttg
     1081 tcagtttgct taaatcttcc atgatttttt gatttatgaa ttatgaattt gatttatgtt
     1141 tgtatttcat gtattcgctc cggagaaagg tgagcgactg ttcaagttgc tctatctcct
     1201 cttcccattc gcgaagcagg cggcgctgtg cctccatgtc ggatgtggcg cgtgtgagca
     1261 gcatatcggc aagaaatgct gcgtcgtcct tcagtttctc ctgccggcga cggatctgcc
     1321 gtccacgccg ctcgatctct tccagtttgt cctttatcgg aatgtaaccc atagctcctt
     1381 agtttttgcc gacagggtgg tccagttcgg ggttaccctc tatgcctacg ctgttgcgct
     1441 tacaatagag gttgtagatg gctgtcagtt tgtcgtccgg tattgcgttg aagttgccgc
     1501 aattggccgc ccgacaggcg atgcctttca catacatcaa cttatgccgg tcgtcacgaa
     1561 acttgtagcc caatttgtcg acccactggc agatggcggc gatcacccgt ttggcagaca
     1621 ggtcgcgccg ttcctcgtag gccatcagtt tcttttctcc cttgggcttc atcgcatcga
     1681 tcatccgact gtactccgac ggatagttct catacatctc gttgagcgag gtggtacgcc
     1741 caccgctatg ttcatgtacg ataccctcct tgatcacttc cttgtaacaa ggatcgtaac
     1801 ccggcgtttc cttcaacaaa gtccagaaga gtgcgtgaga atgttttttc gtttgcctct
     1861 tggttgttgc catactgtat tgtttctgaa tgttatttaa cttgatcaaa atcctgtccg
     1921 tagtaaagaa ctgccttctc ttcccagatg atgaaggggt gcgacttctg tccgtggtca
     1981 aggtaacggc tggcagccac agcacggaaa ccttccacgt aaatcttgca cgaacagtcg
     2041 taacggatgc tgtcggccac accacccttg gggttcttgc cgtcggcgtg actgatgaag
     2101 atgaagagct tacgggggaa gcgggaacgc aggtcgcgat aggtatcgta gtcgatgcgg
     2161 gcatattgca aggagtcgat gataacgata tcccaactct tcggctttgc gagtttttct
     2221 accatctcat cgaagttcat gtccaggagc accacccgtc cgttcacttc catcattccg
     2281 gcatcctgaa acgaacgttg cagtgagagg ctgtcgccct cctccaacga gaggtaggcg
     2341 acacggccga actcggcgag atacttcgcc agacgacagg tgaaggtggt tttccctgat
     2401 cccgactgtc cccagatgat ccatgcgcct tgtggttcgg gacggcccag cagatgatag
     2461 aacgccccgc tgaaatccat cgcctttttc ctttcctgca ggaattgttt tacgcctaag
     2521 atctttccca tcgctacatc tgtccgaatt ggttagcgat ctgttcacgt ttcacaagtc
     2581 gcatcagtcg gcgcaggtct tcgcagaaaa acaggttctt ctccttggtc tcgccccgtt
     2641 tgttggttac tttcacgtag cgcttgatct tgtcaacctc gttccagata cggtcggcgg
     2701 tggcatcgtc caatccgttg gcggtgcaga tttcctttac atcctgctcg gtggctccgg
     2761 gtaattcgat gtagctgcgt cccaagcggc tgtcgatttc gtcatagcct ttggtgttgt
     2821 tacgcacacc acgggcaatc tctttatgca ggttctccgt accggcaagc acacagccca
     2881 aacggtgctc ggtacggttg tagaggggga tcagcttgcg gaaggcggcc ggcttcagct
     2941 tgtcggcttc atcaatgatc agtaccgggt gatcaccggc cataccgttg aaatattccg
     3001 ctatcatctt cagcaaggta ggaatatcgg tatagcctcg cttgggtaca ccgcaggtgc
     3061 gttcggccag ctcaacgagg aactgcctgg agttccactc ctctgcctgg atgaagacaa
     3121 ccgagccggt gagatcctgg ttgaagaggt gttccaaggt ttgtgtcttg ccgcttcccg
     3181 ccttgttcga gatcgccatc cacaaagcct gctgcttgca ggagcggtaa acaaactcga
     3241 tcttgcggta gttctggatg gtggtcacca cctgccagcc gtcttcctga tagcctaaag
     3301 tggaggcgat gcgtttttcc agctcggcgc tattcgcgcc gtacttcccg ttcatccatt
     3361 ggctaagggc ggtacctgat atgccacatt tctctgcaac cttactctgt gatccaagcc
     3421 gggtgatcca gtcacctacg tgtttcaata atccgtttct attcatatcg tgtctgtttc
     3481 tttatatcgt ttaaaaatca tttaaaaagt cactgtgatc atcactgaaa gtgaaatcgt
     3541 cctcttcgtt tgtgatctct tcctgctttg gaactctcag caggaagatc ggttccttac
     3601 gcccggctac ttcgttgcgt acatccttat gtcgacccag cgagtcggtg atcacgtgag
     3661 cagtgagggt attcgacagg tcctcgttct cttcaaacag ctcgcggacg atctcgccgc
     3721 tgcgggtacg tttcagaacg atgtcatcca catactcctt gttgaagttg aacacccggt
     3781 gcagctgttc ggcatcaccc tcctcacgat ctttcagtgc cataggctgt tcgtacttgc
     3841 gttcgaggac gaacctcacg cctccctctt tcggttcttt ctgcgtaccg atattctcga
     3901 cagcgatcac ccggtccatg tcggagggat cgtatttgag gaagaaagtc gtgtgcccat
     3961 aactgcggaa ctccttgtcg aaacattcat actggaaacg atgaccgccc acctgcagat
     4021 gcacgccatc acccctaagc gggcgcggag cagctgtctc gccaaaagcc aacaggaagt
     4081 cttcaggggc aaacagctgg cgatcggttt cgggaagatc gatccaccgg ttgatgtatt
     4141 cctcgcgctt ggtggcgcgg tcgaaatcga tcatctttac caactgctgg cagcatcctt
     4201 cgaaatcggg gaagtcacgt ttgtgagtct cgatccagtc atcagacact tgcagctttt
     4261 ggcggctctt cacgccgtgg ccgctgctgt tgggcaaaag gcgcagccat tgccggttga
     4321 actggttgaa gaaaggttcg atgatcttcg actttgcgtt ttttacagct gccggagtgt
     4381 accagtggcc gaccgcttcg tagaaacact tcagatggcc tcggccgtaa ttgtcggtct
     4441 gcacttgcca gggcttaaaa taagatccga acaactcctt cacatgctcg aaggcgttgc
     4501 ggaaagcctg gcggatcagt gcggccgact cgtggcgacc gatggcataa ccgatgatgt
     4561 atttgttgaa aggatcgaca atggcaacga ctgtgggacg atgatggtag gttgtaacgc
     4621 ttcggccacg actgtcagtg gcatgtgcct ggtagaacag ttccgtatcc catccgtcga
     4681 cacaccagaa gtacatcggc gcagtggggg ccgtacgtgt cacctgcatc agcttgttgt
     4741 tggcaagtgc actctttccg tagcgtccgg cataacattc gggatgttcc ttgcggtagt
     4801 tggcaacggt tgcaccggtg atgggtttcc agttcatacg accggcaacg gcattgtaga
     4861 gccgtgccac cgtctcgttg tcgatgttgc ggccgtcacc gatcagttca acgatcagtg
     4921 cctcctggcg gctttctttg ttcttgcggg cgttgttgtt cttcatcttg ccgctgatca
     4981 gactctcgta accctcctcg ctgtacttca gggcaaccct tttcagcgca agatggttct
     5041 taggcaggcg acagccgacg acatcctgta tctcgttcag ctcacgactg gtctccggcc
     5101 agacgcggtt gtagggtttg ccgtattgct tgatgaagag cgaacggttg cccgtcagct
     5161 ccaagacggc gttcaacgcc gaagcgttgg caacgtacaa ctcgacatat tccggcttta
     5221 ggtggtcgta cggacgcccc tcgaaagtcc agcctcggaa gaactgctct gccatcgggt
     5281 cgcgtcggat catctctttc agcacatagc gtttcggttc ggtttcgaag gtttccccct
     5341 tgcgggcttc cacctcctgc ttgacgcagt cgggcaggga ggcataaaga accaaagcgg
     5401 gcgtaccgta acaggcacgg ttcagcacct gcagtttgcc cgtcttcttg taatatttga
     5461 agttggactc cgacaggatc ggccgtttca gcggatcaac cgccaacgga tcgcctgccg
     5521 tcagctcagt gtatgatatg cacagttgat tcttgtagaa ttccatatcg ttccgttttt
     5581 agaaatttat cattgttccc ggaagcggat tcgaaccgct gaccatatcg cctgaattac
     5641 cagttccgat tgttctgcct gactgaacta tccgggatac caccctcgta ccgcgggccg
     5701 cgtaccgatg ctaaaccaaa accaatatta attgagacct aaaccgattg tttatccttg
     5761 tcgctgccac caagcagccg aaccatccat tcttcgaaac ggactacttc gcgcttgcaa
     5821 gccgcttcgt taccgatcaa catgtagctg aagaagaacc agaccgaaca gagcagactt
     5881 cccgtcagca tgctgccgtg ttccatcgtt ccgattccgg caaacaggga cagccaactc
     5941 aatgcccatc cgtaaagtat caccttcgcc ttcataattc tccattgtca attacccagt
     6001 tgtgcctttg ccagcatctt ggtttcaatc acgagagcgg gatcagtcag ttccatccag
     6061 ccgaagcgtg tcttcagcag ccggtctaat accgcccagt tctccaagct gacacagtcg
     6121 ttgtagttgt accattgcgt ttcgccagtt ttcgggtcca agccaatgat cccccaaaac
     6181 tccttgccct gctgcccgat gacaaccttg cacgcgccct tcgcgaacac cacgcggaac
     6241 accgggcgtt cctcctcttt cctaccggta taaaccagca tagggaagtt gtcttcatac
     6301 aatgattcca tttcaaacgg ggcttcacac aacgctttgt agtcgattct ctttgtttcc
     6361 atctttctgt cgttttagaa ttatctgttt gtcccgactg cggtctcgct ccgctacgtg
     6421 cgagtcataa gctctcttgg ccgggtgtaa gggttagcag tctttatatg tcgcgattaa
     6481 gatttctctt tgtcccactc gatgcacatc tgctcgcaga ttggcacagg gtcgggatag
     6541 gtgatacctt gacttcggtt ctgcttggcc aggctggtga tccgtcgaac cacgtcttcg
     6601 ctgacagatg tcccggcata gaccttgcgc acgtgcggat aactaacatc tataccttct
     6661 gccacctctg ccaactcgtt ccggctgata tagggcttca cccgctgctt ccattcctcg
     6721 aagaacgggc ggtacttcgg aaggggcagg cgctggcgct gttgttgctc ccgcatgcac
     6781 tccgcctcgc ccttgatccg atactgcccg gtctggcgga gctggggaag aacctcaccg
     6841 gctacccagt tgacgaaggc atccgcctgc ggcttattac tccggaacgc cagtttgtag
     6901 agggccgctt cgttgatgac tgacaactgt tgcacacctc cgccgcgatc accagaagaa
     6961 ggggtgttaa aactcatcat ccctttccaa tcatctggaa tattggataa tgtagcaccg
     7021 ctccaagcga tatctaaagc gtttgccaca tccttggcta caaaccaagg ttcgttgttc
     7081 agttgctgcg tgcgaattgt tacgttcgcc tcctcgttgt agaataattg caatttgttt
     7141 cccatttcaa ttcgatttaa atgattgtta cttccttata ggggttatcc acctctttct
     7201 tagtgatctc gaacattttt cctccatgat ttaaggcata cgcccggatt aacttggctg
     7261 aagggctatt cgtttcaaac cggagcgcag actggacggt cctctctgtt acagccagtt
     7321 ttttggcgat ttcacgttgt aataccagcg tcacagtgat ctcgtttcgt ttttcttcca
     7381 tattcgttgt aattattata tgttttgttc gtacttttat agcgtctttc tattggaaga
     7441 ctttgcaaat atggttgata attttcaacc atgcaaataa aatagagata attttcaact
     7501 aaaatgaaga caattttaca gcgtatagaa caaatagcta taaatgaggg gataaaaatc
     7561 accacatttg aaaaaagtat tggtgcaagt aagggagtat tatccagggc tattaataac
     7621 ggaaccgata ttcaatcaaa atggcttcag tctattgttg aaaattatcc ccgatattcg
     7681 gaagcatggc tccttactgg ccgtggctct atgctaaaag aagagccaaa atcttctcaa
     7741 gtggattgtg aaccttcagt atatgcaaat accgatcttg ttcgtatccc ggttgtcgat
     7801 atctctgttg ccgccggatc aggattctgt aatacggatt atatagagga agtggagtct
     7861 atttctatgc cttcttccat ggtaaaagac ggcaagcagt atctctgtgt gcgggtaaaa
     7921 gggcatagta tggttccttc tatccttgat ggaggttatc tgatcattcg caagatcgaa
     7981 cgttctgaat gggaaggtat acgtgataat tatgtatatg tggtaagtga cacggagggg
     8041 cgttcgtatg tcaaacgtct taagaatcgg ttgcgtcagc atggctttat cgtttgcatg
     8101 tctgacaacg cggataaaca aaattatccc aacttcaacc tatatgaaga agaactgaat
     8161 acaatatggt atgcggaatg gtacttcagc gcaaagattc ccaatatcca agaggtctat
     8221 tatcgcaaac aaggcgaact ggaagatcgc ttggatgaac tgacggccca attccaacag
     8281 tttcaaaagg ctttaaacaa taataattga tatgagaaca gttgatttaa acgagatatc
     8341 cgagtttgag aaagagttcc gccgcctgcg gttcaatccg atttacttct atgagtatta
     8401 ttggaaagaa aaacatccag acgaaccgga actgacacgt gagcagaaac aaaagttgta
     8461 tgacgaatac cgtggaaccc ctttctttca ggatttcggg gaggccatca agcatcaaga
     8521 acgaatcaaa gagctaaaag cccaaggcta tgaagattgg gagatcatgg ggtaacacct
     8581 ccagttatta ttccacggaa tagggcaaac cggatttgat ataacggata atattatcag
     8641 cctcaaatgc ggttcgattg ccgtccggat tatggttgcg gttcacaagt agccttagaa
     8701 tgattttctt tctaaggcgc ttttctttcc attcttttat ttttgatata aggcaactta
     8761 tgatcataaa acacctcctt tttttgcaaa tttagccatt tccccggcat tatctatacc
     8821 taaacctaat aaaaaacacc ataacaaatt gtatttcaat taaatataat tacaacaacc
     8881 attccaaccc cgcaaaacta tggaaatagc cccccctcta atcatatcta aaccctattg
     8941 ttttaactga atttaaccca ataaccccca tccgaacggc tcgtttttta cgaaaatact
     9001 atccccaaca ctatctccaa cactatcccc aaccccaaaa acgccaaaaa acgaaatgta
     9061 taggttggag ataaaaaaag gcagcattcc agctaaaaaa gccgaaacac cgccccaaaa
     9121 cggattgaaa ctggattata tatttaaact attgcatttc aactatttgc cacccctaat
     9181 caggtgcgat tgtatgatca tagcccgttt ggtcacttta cagctgccat ccgtcattcc
     9241 ggcatgtaaa aggctactct ttgtgatccc tatttcctcc tctgtgaggg tgttgaagat
     9301 cgctgaaata gacccgaaat agtagttctt cttctcaaat atcagatgta catgtataac
     9361 tttcgtcatg tcttatttag aatgttttat actacaaata taccaaataa ttattatttg
     9421 gaagtttttg aataaaatat tttttctttc atccaccaaa cacctgccat cagacaacaa
     9481 aaaaaggagg ccgtttaaag cctccttctg atgtctgcat tcaaaccatt gtactaactc
     9541 caaaagccac ttcacagcgc ctaaatctgg cggattgcaa ggcatatttt aatcacgctt
     9601 aaatcttctt tcaaacacta tccccaactc ccttgtttca accctcattt tttcaactcc
     9661 aatgcaagtc aattaaacaa acctatactt ttcgtttttt ctctcaacct cttctatttt
     9721 ttctgtaatt cattgtatat cttttatata acatacaact ccaaactatc cccattatga
     9781 cttttcgttt tgccccttat ataaacaatt ccacttatca agtcgaatat ctgttcgaac
     9841 acgaagggtg taaggtctat cgtttcatgg atatgggaca ttacatctat ttcaccaact
     9901 gcgagggaga tgttaccagt attgaaagcg acagcgtccg cacagtcaac cggatcagcc
     9961 gtaaaccgat catcatcaaa gagcagacac tcgattaggc ttatacggtt atcccgtgtt
    10021 tactaaagat cgctttagca ttggccagac gttctgctga aagcggttcc acacctttca
    10081 gcttatagtc caggccttgt gcctcatatt tgtaagctcc cattgtatga taaggcagaa
    10141 gttcggcttt ctggaccacg ttatatgaac tgatatattc ggccagcttg ctcaaggctt
    10201 catcatcgtc cgtcaggccg ggcacgatca cgtggcgaat ccatacaggg atgccgcgtt
    10261 tctccagttc atcaagaaag cgtaaagtat tatcgagttt tacggccgtc aaacggggat
    10321 gaagaccggc gtcgatcgtc ttgatatcta acagaaccag atcgacctgt tcgagcacct
    10381 ccaatgcttt accggaacag atatagccgg aagtgtccaa cgccgtatga ataccgttct
    10441 cacggcaaag gcggaaaaac tctttaagga attcaggttg taacaaaggc tcgccaccgg
    10501 tcacagtaac accaccttta gcgataaaat tcttatagcg tagcacttcg gcaagcaacg
    10561 cttcaggttc cagcagataa ggcgtttcac gctttacctc ccaggtatcc ggattgtggc
    10621 aatacagaca acgaagcgaa catccctgca tgaaaacaac aaagcgaatt ccgggaccgt
    10681 caacggtccc gaaactctct aaagaatgta tacgccccaa catattaatc aatggacaat
    10741 tataaactgc tgttgatggt gcgcgagatg acgtcgagct gctgttcgcg tgtcagctta
    10801 acgaagttga cggcatagcc cgaaacacgg atcgtaagct gcgggtattt ctccggatgt
    10861 tccatcgcat ctaacagcaa gtctttatcg aatacgttca cattcagatg ctggccgcca
    10921 tcgggcgtga aataaccatc taagaggctc actaagttgt tcacctggat atcgcgttcc
    10981 ttacccaacg ttgcaggaga aacggcgaat gtataggaaa taccgtcatg cgcatgctga
    11041 aaaggcagtt tggcgacaga agccaaagcg gcgacagccc ctttcgtatc gcgtccgttc
    11101 atcgggttgg ctcccggagc aaacggcgta ccgcccggac ggccgtcggg agtcgttccg
    11161 gttttctttc cgtagaccac gtttgatgtg atcgtcagga tagattgtgt cggagttgcc
    11221 ttgcggtatg tctgatgctg gcgcagatat tccataaact tctcagtaat gtcgacagca
    11281 atactgtccg tgcggtcgtc attgtttccg aaaggtacat attcgccttc gcgttcgaag
    11341 tcgacagcca aaccacgttc gtcacggatc actttcactt tcgtgtcacg gatggcagcc
    11401 agcgagtcgg caacgataga aaggccggcg ataccggttg cgcggatacg ttccacatct
    11461 ccgtcatgaa gccccatctc gaatgcttca tacgcatatt tgtcgtgcat gtagtgaatg
    11521 atcttcagtg cattgacata gacttttgcc aaccagcgca tcatctgctc gtatttctcc
    11581 atcacttcgt tgtagtccag atactcgctg gtgatcggtt cgaaacgggg agccacctgc
    11641 acacccgatt tctcgtcacg tccgccattg atcgcataca acaagcactt tgccaggttg
    11701 gcacgagctc cgaaatactg catctgctta ccgatcttca ttggagaaac acagcaggcg
    11761 ataccgtaat cgtcgccata gtccggacgc atcagatcgt cgttctcgta ctggatggca
    11821 gaggtatcga tcgatacttt tgcgcagaag tttttccagt tatccggagc attgttgaac
    11881 caaagcaccg tcagattggg ttcgggtgcc gggccgaggt tatacaaggt atgcagataa
    11941 cggtaagatg tctttgtcac cagcgaacgg ccgtcaacac cttgtccgcc cagcgattca
    12001 gtcacccaaa cagggtcgcc ggagaacagg tcgttgtatt ccggagtacg caggaaacgg
    12061 acaatacgca gtttgataat aaactggtcg atcaattcct gtgcctcttc ttccgtcagc
    12121 ttgccttcgc aaatatcttt ttcgatatag atatcgagga aagtagaagt acgtccgaga
    12181 gacatggctg ctccatcctg atcctttacg gctgccaggt aagccagata caagaactgc
    12241 acggcttcgc gggcatcctt tgccggacgt gtcacatcga aaccataacc ggcacacatt
    12301 ttctcaaatg ctttcagcgc tttgatctgc tccgttatct cctcacggct ctgaatgatt
    12361 tcttctgtca gttcctgtat atcgagacgt ttttggaaac gtttcttttc ttcgatcagg
    12421 atctgggttc cgtacagagg tacacgacgg taatcaccga tgatacgtcc gcgtccgtaa
    12481 gcatcaggca acccggtaat gatggcggaa cgacgtgccg caatcatctc gtctgtatag
    12541 gctgaaaaaa cgccttcgtt gtgcgtcttt ctgtatttgg tgaagatctc ttttgtcatc
    12601 gggtccagat gataaccata ggcttccaga ctgttttcga ccatgcggat accgcctttc
    12661 gggaagatac cacgtttcaa cggggcatct gtctgcaagc cgacgattac ttcgttttcc
    12721 ttatcgatgt aaccgggtcc gtatgtgtca atcccctggg gaagcttcgt ttcggcatca
    12781 tatactcctt tctccctttc aaccttaaac atctcggtta gtttgttcca cactttcttc
    12841 gttttctccg aagagggtac gaggaacgta tcgtctccgt tataaggttt gtaattgttc
    12901 tggataaagt ctcttacatt gatctccttt ttccaggttt ctcctttgaa ctgcgcccag
    12961 ttctcgtttt caaacttcat aagcttatct tgtctatttc ggtttaggca cgcaaagata
    13021 cgtcttttcc ccctatctga aaaggattgt aaaggacgag ggatgttaaa ccggagaaaa
    13081 tacctacaaa tagggataag ggaaataaaa acgaagcccc ggcagtacga ataccgccga
    13141 ggcctgtttt ttgtctgccg tccggtcttc acagagggaa aagcagtaga acttttaatt
    13201 tcattacttt agtattatta atattaaatc caaccgctcg ttcgcctgtc gcagggtaat
    13261 tgaaaccgta gatcaagaaa acctcttaca tacggtttca cgcaggttgt ctagaattat
    13321 ttgattataa aatgtcattg tgcctgtgta agggtggttc actaaccacc cttacgatag
    13381 acagtattgt ttttttagta tcaatcgtta cttaacgata gcttttacag cagcttcgcc
    13441 ttcaacagct acaactacta cgcctgccgg agcagcgatt acagcgttgt cagaagagat
    13501 tactgtgttt gctactacct gacccaagat gttgctgatg acaaccttct tgccggcagc
    13561 acctgcgatt gtcacattgc cttcgccggc gagaactttc acttcagata cggctacgcc
    13621 ttcgttggct gtcggagtag actgggattc gatcaggaag cgaacagccg tgttcttgtt
    13681 tgcttccaga tagaagtagc tattgatcat ctgaacatag tttgcacgac cctgacggat
    13741 cacatattca tcgctaccat cttcagcctt gatgatctgg aactggaagt tgtccaaacc
    13801 gcctttgatt ttcttcggag cattgtcttt ttctgctacc aggacagatt ttccgtcaac
    13861 gacagtgcgc aatgtgtcgg aagagaccaa ttcaccagca ttgaagatca gcttagcagc
    13921 ttcacctttc tggttttcca agttgaagcg gtagttgcca cgagcttcgt aatactcaac
    13981 agagtcttct gcattgtata agaagtgacc agccttagaa atgtagaacg taggaatatt
    14041 cttgtcagat ttaactgtgt ctacccagaa tgtcaagtct tcacttgctt ccgtcgcgat
    14101 gctctggaac gcatcgttgt ccttgttcgt caagaaaccg ccacgagtca gtgcgaaaga
    14161 tacgtgctgc ggaacagctt ctaggctgac agccggagtt tcgtcaacca tgaaggtctt
    14221 caggcctttg tcgatcttat gctccaactc gtagttgtat gcatctttcc aagcagtttc
    14281 tctgtctttc tttaagtcat taaccattgc gaaagctcca ttaacatcag ttgtagtcgc
    14341 agctttgatc aatgatacgg aaccatccaa attctgcttg atgatgaatt catctgcaga
    14401 cacatctgtt gctacttcaa gttcccaagt gttgctcaga tatctgtcgt ttgcatcatc
    14461 aaacgcctta accgcataag tatagaaagc gactgtgtct ctttctgttg aagtccgaat
    14521 acgtttgcca tccaagtaga tgtaattgtt caatacatta accggctttt tgctcttaat
    14581 cagttcaaac tgaaccatgc tgtctgcatc ggcataagcc aagatgtctt tgtttggtgc
    14641 cagattgcca tctacgtctt tctcgccacc aacatagaat gccggagcga tatcgctgtt
    14701 aagggccaat tcgaactgaa ccaagcccat gttgtcagct ctgttcacga atgtagcgaa
    14761 cttgtcttct acagtgtacg gagtcaggac gatcttcatg ttcgtcaagt caatagcttc
    14821 aaaagtaacg acttcatcct ttgaattatt tccaactgta ccattgatat attctacata
    14881 taccttatcc ttgctgcctg ttgccggaag tactgtatat acaccatctt cgttttcata
    14941 cagcgaaaca gtgaaatcaa cttttgtttg acggttagcc aaagtgattg tcttgtttgt
    15001 cttgtcaaca cctgttacaa caaactggta catcgggtct gcttcgttga aatcaacagt
    15061 agaagctaat tcgaaaccag ccggtttatt cacagtcaga tattgttcat actcagaagc
    15121 accttcattc ttttcaccgc ttacaaactg gattgtgtaa acagatggtg catcttcttc
    15181 ctgcaagaag ccaactaaac catcaccatc caacagagta gtattagtcg tagtgaaagc
    15241 caaagcatca gtaacaacag tagttaccat gtagttctta ttctgatcag cgatacaacc
    15301 aatataaaga ccagccttgg cgacgtgctt tttagctgca ttgtctgttg cagtaacaaa
    15361 cacgtgaata ttcttggctt tgatattgta tgtttccgga gcagtcactg cattaggaac
    15421 ttcaactacg aaacaagcat tgcctacgaa tacctcttct gcatgagaga agttgtcaga
    15481 tgtagcagca ccatggaaaa agttcatttc actaccctgc atagttatca gttcgtaacc
    15541 taagccatta tcacggtcag tcgcgttgat gtcatagttg cctgtcgggt cgatagcaat
    15601 gaacgtgcac tgtttgaaca gatccgaatc agcaatctta tctgttccga ccaattcttc
    15661 cggataagaa gtagcaaagt aaacacctgc gggaatcttc atgtcgttac ctaggtcaaa
    15721 atcgttatca acataaaacg ctttcaattt cacatcagac agaacatcgt ttgcccaatc
    15781 caatttcttt ttaggagtga aatcgaagtt aaaaccttcg ccagccatag tctcgttcat
    15841 ggcttcaaca gctacttggt caaccaattc ctgggtttta agtttgtaga gatacaactt
    15901 gcttccagtt aaacctacaa tagaggtaag ttctgcacgt gtcaatgaaa caggattcaa
    15961 ccctgcccct cctgcatagg gatacaatcc tgaaccttgc aaaaagcggc ttgtaaaatc
    16021 attagacagc actgagaatt gagtatacaa atgattagcc gcatcaagtt tacaattttc
    16081 taatttttct ataagatctc ctgattgatt tactgtcaac ggcttaccag aagcagcgct
    16141 agtcaaagtg taataatagc cattaggtac accagcaaca tctttcacgg gtgtttcagt
    16201 aaaagtccaa gtaatctctt tcaacttagc accagttgcg aaagctgaaa gattttcacc
    16261 atagtacttt acagttttac catcctcact aactactgct tgcagcaaaa gatcagagcc
    16321 ttcaagcgta ccatcctcat cagcaaccag cacataagga ccgcccgtcc atgcagcatt
    16381 attggcagga gcagcaacct tctccaattc aatcccatta attgtaggag cagtctgcgc
    16441 ccaagcacta ccacacaacg aacttgtagc caacaagccc attgtcaaaa gagtagaaaa
    16501 cttcttgttc ataatctaaa atgtttaatt aataatgcga atcagcagtt ggctttctga
    16561 ttcaaaaatt aaaaattaac aaatg
//
