LOCUS       c00166_gnlPro..        14667 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MGJKFHMJ_176.
ACCESSION   c00166_gnlPro..
VERSION     c00166_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 20:19:20
            Original ID  :: gnl|Prokka|MGJKFHMJ_176
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14667
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14667
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1153:4667]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1154..4667
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14667
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14667
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             193..1032
                     /locus_tag="ctg166_1"
                     /transl_table=11
                     /translation="MPSICQGTWDCQICPKAVSNAITHVIYQRGFHKPAQRCEENFILF
                     LIKGEMLVNSKEYAGTMLKEGEFILQAIDSTFEMLAMLECECIYYRFIQPELFCDSRFN
                     HIMKDVSPPLIYSPIKIVPELQYFLQGSITYLKGNKVCRDLLSLKRKELAFVLGYYYSD
                     YDLSSLVHPLSKYINSFHYFVIQNYKKVKTVEELAQLGGYTLSTFRRIFNNVFHEPVYE
                     WMLARRKEGILDDLNNSAYSISEICYKYGFESLPHFSNFCKKSFGASPRNLRGQNRS"
     CDS             complement(1154..1909)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg166_2"
                     /sec_met_domain="Fer4_7 (E-value: 2e-12, bitscore: 38.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 1.5e-25, bitscore: 80.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 9e-07, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQAGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISERKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFQDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIPKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNISISNIARLNRDFIIAKLKD"
     CDS             complement(1946..3925)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 201.7; E-value:
                     7e-62)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg166_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.2e-62, bitscore:
                     201.7, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 5e-37, bitscore:
                     117.7, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLYTRYEMQDVVIVDGRARGIIAKNLVTGELERFAAHA
                     VVIATGGYGNAYFLSTNAMGCNCTAAISCYRKGAVFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKKEDAVKLQKGEIKGSDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSEAINRLGIDIVLQRYGNLFDMYEEITDVNPGE
                     LAKEINGVKYYNPMMIYPAIHYTMGGIWVDYELQTTIKGLFAIGECNFSDHGANRLGAS
                     ALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAEAEKAVQAKIDKFMSIQGKES
                     VDSIHKKLGHVMWEYVGMGRTAEGLKKGIAELKEIRKEFETNLFIPGSKEGMNVELDKA
                     IRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDENFFYVACWEYQGDDE
                     KAPVLYKEPLVYEAIKVQTRNYKS"
     CDS             complement(3963..4667)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg166_4"
                     /sec_met_domain="SucD_FumR (E-value: 1.3e-131, bitscore:
                     426.9, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVAIISADGYNMI
                     CEFLGANWYALVATAGLAALFVIHIIYAFWLTMQNRKARGSERYAVTDKPKTVEWASQN
                     MLVLGLIVIVGLGLHLFNFWAKMQLPELMHNMGMHADTLTLAYAANGAYHIQQTFSCPV
                     YVVLYLVWLFALWFHLTHGFWSSMQSLGWNNKVWIDRWKCISNIYSTIVVLGFALVVVV
                     FFVKTLICGGAC"
     CDS             complement(4879..5748)
                     /locus_tag="ctg166_5"
                     /transl_table=11
                     /translation="MPGDSFCIQYTNCTGCPKATENILVYRNLPKGEHIPKDKCTQNCM
                     LFMIKGELLINSEEYPGNTLREKQFILQAIGSKVEILALTDVEYVVYWFNELPLLCEER
                     YKEMMEQTGAPLTYTPLVMSERLYHLVTSMPEFLGEETPCSKYINLKCKELVFLITNFY
                     PLPQLSSFFYPISTYTESFHYFVMQNYSNVKNVEEFAHLGGYTTTTFRRLFKNLYGMPV
                     YEWILEKKREGILEDLQHSKMRITEICNKYGFDSLSHFAHFCKDSFGDTPRALRKKAAG
                     GEKIGKVQ"
     CDS             complement(6077..7669)
                     /locus_tag="ctg166_6"
                     /transl_table=11
                     /translation="MNKLLLTGFLTAGAAIHNLSAQTTAGQGNQQKDEQRPNILFILSD
                     DHTSQAWGIYGGVLADYAYNNNIRRLANEGVVLDNCFCTNSISAPSRASILTGLYSHRN
                     GLYTLADSLNTSIPTLATVLQSHGYNTGLVGKWHIKSQPQGFNYYSIFYDQGEYRDPTF
                     IESSDPWPGNRRFGERILGFSTDLVTEKAINWIKQQDGKQPFLMCCHFKATHEPYDYPI
                     RMEHLYDDVTFPEPENLLDWGPETNGRSFKGQPLEELVRRWKIASKDPDKWWCRYPGLP
                     FSTEGMQRTTARRAAYQKLIRDYMRCGATVDDNIGKLLKTLDEMGIADNTIVVYVSDQG
                     YFLGEHGFFDKRMFYEESARMPFVIRYPKKIPAGERLKDLILNVDFAPTLAEFAGVKME
                     NVQGTSFVNNLEGKTPPDWRKEIYYRYWTNHAIRPAHFAIRSDRYKLIFYYAQNLDMTD
                     TGNFEFTPSWDFYDLQNDPHENHNAYNDPKYAPVIKQMKKQLLNLRKEVGDTDEKYPEM
                     QELLEKYYNKDMR"
     CDS             7921..8076
                     /locus_tag="ctg166_7"
                     /transl_table=11
                     /translation="MLMLRKIVFFLFLFVGLSLFAQQDYMISSYVRGNFYNRGRISTES
                     CGQVTI"
     CDS             8082..8882
                     /locus_tag="ctg166_8"
                     /transl_table=11
                     /translation="LSVHPNKDGSLLFENPRAFQGKGETTWEGLIKSVRGKVKGTKAKI
                     RLGASSGEWKAMVADEAARTTFAKNIKKVLEKNNLDGIDLDFEWAENEKEYEDYSLAIL
                     KMREVLGDKYLFSVSLHPVCYKISKKAIEAVDFISLQCYGPSPVRFPIEKYCSDIQMVL
                     EYGIPKEKLVAGVPFYGVTKDNSKKTEAYFNFVQDGLITSPSQNEVIYQGDTYVFDGQD
                     NIRIKTRYAKEQKLKGMMSWDLATDLPLNDSKSLLKTMTEELRK"
     CDS             complement(9093..13211)
                     /locus_tag="ctg166_9"
                     /transl_table=11
                     /translation="MKKHITSIFFLCLLSVSQLIAQSHSIKRLGIEQGLSNNYVISIAQ
                     DKQGFLWFATEEGLNKFDGTRFMTYYKNDLSQSSQGITGNELNRVYADNKRPIIWIATQ
                     RDGLNAYNYNKQVFTAYSHNPDDPHSLITNDVTDIAPSAQHEDGLWISTYYRGIEYLDI
                     NSGQFTHYNKNTVPALSCEQTWTVLDGGDGNLYIGHVGHGFSILSLKDKSVKNFQNHSD
                     DPKSLPGNDVRCLTKDTNGNIWLGTDKGLALFNATDQSFITFKNNKNDKYAALCNRILA
                     IKQLNDGKLWIASELNGITILDLKQSMFLSPEQISLEYIQEGDDSRSLSNASARCIFQD
                     SFDNIWIGTWGGGINFISRKPPLFTTLSYSPIPNNENSLNNKVASSLCTDRQGRIWIGT
                     DGGGINVFEGDKRIAIYKKETGDIPSNFILTSLQDSKGNLWFGSFQGGISYYDTRNKRF
                     RSISLMGQYNQDVRTIYEDTQHNIWVGYSGGIIVLNPLNMEIIRHYNTENSELHSDFVR
                     SIAQDEKGRFWIGTFGDGLGVYTPDLQQIKTFVQREGFCSNTVNQIIQDKHKRMWIGTG
                     EGLVCFPSTNVLTYKTYQRKDGLTNTNICAITEDKKGNIWFSNNKGVSCYVTAKDCFYH
                     YGHSDDVPAGSFSSGCVTQNKNGWIYFGSINGVCCFNPDITMNEQPTPVAVITEMKILG
                     RLSNLENNDMIINLSKGQNVELSHAQNSFGLTFNVQNYSLVNQVEYVYMLKGLENSWYT
                     VNENNSVTFRNIPPGKYEFLIKARVHNQEWPEEATSLTIRVNPPLWLTWWAKLIYILVS
                     ISIIYLILHAYKKKLDLESLYILEKKNHEQEQELNQERLRFYTNITHELRTPLTLILGP
                     LEDMQKETSLPAKQAQKLSVIHQSALRLLNLINQILEFRKTETQNKKLCVSKGNIAPLI
                     YEIGLKYKELNQKTKIDFQIQIEKEEMFLFFDKEIITIVLDNLISNAIKYTEQGRVTLS
                     LYQTMRNEVAYTEIKVSDTGYGISAEALPHIFDRYYQESGKHQASGTGIGLALVKNLVT
                     LHEGEIRAESIQNEGSSFYISLLTDNIYPNALHADSTEPVQEETNPEASLEYPQETTLD
                     TGKPILLIVEDNEEIQKYIAESFVDSFEVLTAYNGEEGKQQALSRIPDIVVSDIMMPVI
                     DGITLCRQLKEDVRTSHIPVILLTAKDSLQDKEEGYEVGADSYLTKPFSASLLRSRINN
                     LLESRKKLIAQFQTQSVPGNQADLKEKRIVIAEALSKLDNEFIEKITLLIEENLSSEKI
                     DITYLSDKMCMSGSTLYRKMKALTGLSTNEYIRKVKMQNAERLLLEGKFNISEIAYKVG
                     MNSTGYFRQCFKEEFGVSPSDYLKQIIQS"
ORIGIN
        1 tcccaactag tttctaaggg aaaggatatg aggaagcttc gtttaaaaaa caaacttaat
       61 attcttctta gtagatatct ataaactttt cacatagcct attttttact tttcttccca
      121 ttttttatgg ctatatgaaa gatttcatat atttttgttg gcagcataaa caaatacaaa
      181 cacagccagc ttatgccatc tatttgtcaa ggaacttggg attgtcaaat atgtccgaaa
      241 gcagtgagca atgctattac tcatgttatt tatcagcgtg gttttcataa accagctcag
      301 aggtgtgagg aaaattttat tcttttcttg attaaaggag aaatgctggt taatagtaag
      361 gaatatgccg gtaccatgct caaagaaggt gaatttatac ttcaagctat tgattctaca
      421 tttgagatgc ttgccatgct cgaatgtgag tgcatctatt accgttttat tcaaccggaa
      481 ttgttttgtg attctcgttt caatcatata atgaaagatg tatcgcctcc acttatctat
      541 tccccaataa agatagttcc tgaactacaa tattttttgc agggttccat cacttattta
      601 aaaggaaata aagtctgccg ggatttgttg tctctcaagc ggaaagagtt ggcatttgtg
      661 ttggggtatt attattctga ttatgacctc tcgagtctgg tgcatccgct ctctaagtac
      721 atcaatagtt tccactactt tgttatccaa aactataaga aagtaaagac agtagaagaa
      781 ctagcccaat taggaggata tacccttagc acattccgtc gtattttcaa taatgtcttt
      841 catgaaccag tttatgaatg gatgctggca aggcgtaaag agggtattct cgatgacttg
      901 aataattctg cttatagtat ttccgagata tgctataaat atggttttga gtccttacct
      961 catttctcta atttctgtaa gaaatctttc ggcgcttctc cacgtaattt gcgtggacaa
     1021 aaccgttcat gataactgat tattaataat aatcatgatc cattcatata taaagaaatc
     1081 ccctgtcgga ctagccggca ggggattctg tcattaatca aattaagctc tcgctctcga
     1141 aatctagcaa tttctagtct tttaattttg cgatgatgaa gtcacggttc aagcgggcga
     1201 tgttgctgat agagatgttc ttcggacatt cagcctcaca agcacgagtg tttgtacagt
     1261 taccgaatcc cagttcatcc atctttgaca acatagcttt tgcacgacgc aaagcttccg
     1321 gtttaccttg cggcagcaag ttcaactggc taacttttgc agaaacgaac aacatagcag
     1381 agccattctt acatgcagct acacaagcac cacaaccgat acaagaagca gcatccatag
     1441 cttcgtcagc gataggcttc ggaatcagga tagcgttagc atcctgcgga gcacctgtac
     1501 gtacgctcac gtaaccacca gcttgcataa tcttgtcata agcagtacgg tctaccatca
     1561 agtccttgat tacagggaaa ccggccgaac gccaaggttc aacagtaatc gtatcaccat
     1621 cctggaaacg acgcatatag atctggcaag tagtagcacc tgttgcagga ccgtgcgggt
     1681 gtccattgat gtaaagagaa cacataccgc agataccttc gcggcaatcg tggtcgaata
     1741 ctaccggttc ttttctttcg ctgatgagct gttcgttcag aatatccagc atttcgagga
     1801 aggaagtatc gccggggata tctttcattt ggtaggtttc aaaagcacct ttagccttcg
     1861 gaccagcttg gcgccatacc ttcagtgtaa atgatatatt tttatccatt ttcttctaat
     1921 tcttttaaat gtttaacttc accgattagc tcttgtagtt acgggtttga accttgatag
     1981 cttcgtatac cagcggttct ttgtacaaca ccggagcttt ttcatcgtcg ccttgatatt
     2041 cccagcatgc tacatagaag aagttttcgt catcacgttt agcttctcct tcttcagtct
     2101 ggtattcttc acggaagtga ccaccacaac tttcgttacg gttcaatgca tcgtaagcaa
     2161 caagctcacc cattgtgatg aagtcgtaca gacggattgc tttgtcaagc tctacgttca
     2221 taccttcttt agaaccgggg ataaacagat tcgtttcgaa ttccttgcgg atttctttca
     2281 gttcggcaat acctttcttc aagccttctg ccgtacgtcc catacctaca tattcccaca
     2341 taacatgacc cagtttcttg tggatagaat caacagattc tttaccttgg atgctcatga
     2401 acttgtcgat cttagcttga actgcctttt ctgcttcagc aaattcagga agatcagtag
     2461 agaaacgagg aacagtgatt tgatctgcca gataattctg gattgtataa ggcaatacga
     2521 agtaaccgtc agccaaacct tgcatcaatg cagaagcacc gaggcggttt gcaccgtggt
     2581 cggagaagtt acattcaccg atagcgaaca gacccttgat agtggtttgc agttcgtagt
     2641 ctacccagat accacccatt gtatagtgga tagctggata aatcatcatc ggattataat
     2701 attttacgcc attaatttct tttgccagtt ctcccggatt aacgtcagtg atttcttcat
     2761 acatatcgaa gaggttacca taacgttgga gaacgatgtc gatacccaag cggttgatag
     2821 cttcagagaa atcaaggaat acggctaaac cagtgttgtt tacaccgaaa cctgcgtcgc
     2881 aacgttcttt agcagcacgg ctggcaacgt cacgcggaac caggttaccg aatgccggat
     2941 agcggcgttc caagtaatag tcgcggtctt cttcaggaat atcacttcct ttgatttcgc
     3001 ctttctgaag tttcacagca tcttcttttt tcttcggaac ccagatacga ccgtcgttac
     3061 ggagagattc agacatcaaa gtcagtttag actgcttgtc accgtgtacc gggatacaag
     3121 tcgggtgaat ctgaacgtaa gcagggttag cgaatacagc acccttgcgg tagcaagaga
     3181 tagcagctgt acagttacat cccatagcgt tggtagacag gaagtaagca ttaccataac
     3241 caccggtagc gataactaca gcgtgagcgg caaagcgttc cagttcacct gttacaaggt
     3301 ttttagcgat gataccgcga gcacgtccgt caacgatcac cacgtcttgc atttcataac
     3361 gagtgtacag ttttacagta cctacgttta cctgacggct caatgcagag taagcaccca
     3421 gcaacaattg ctgaccagtc tggcctttag cgtagaaagt acgggatacc tgtgcaccac
     3481 cgaaagaacg gttgtccagt gtaccaccat attcgcgagc gaaaggaaca ccttgtgcta
     3541 cacattggtc gatgatagcg ttagacactt cagctagacg atatacgtta gcttcacggg
     3601 cacgatagtc accacctttt acagtatcgt agaacagacg gtaaacggag tcaccgtcat
     3661 tttgataatt ctttgcagca ttgataccac cctgtgcagc gatagagtgt gcacgacggg
     3721 gggaatcctg aatacagaaa ttgaatactc tgaaacccat ttcaccgagt gaagcagcgg
     3781 cagaagcacc tgccagacct gtacccacaa cgatgatgtc caaacgacgt ttattagcgg
     3841 gattcaccaa tttctggtga gctttatagt tggtccattt ctcagccacc gggccttctg
     3901 gaatttttga atctatcttg atcataatat tatttacaat ttaatcattt acaatttact
     3961 atttagcaag caccaccaca tataagtgtt ttcacaaaga ataccactac taccagtgcg
     4021 aaaccgagta caacgattgt agaatagatg ttagaaatac atttccaacg atcaatccat
     4081 actttgttgt tccatcccag tgattgcatt gaactccaga aaccgtgagt caggtggaac
     4141 cacaaagcaa acagccaaac aaggtaaaga actacgtaaa ccggacaaga gaaagtctgc
     4201 tgaatgtgat atgcaccgtt agcagcataa gccaatgtca atgtatcagc gtgcatgccc
     4261 atgttgtgca tcagttccgg caactgcatt tttgcccaga agttgaagag gtgcaaacca
     4321 agacctacga taacgataag acccagcacc aacatgtttt gagatgccca ttctacagtt
     4381 ttcggtttgt ctgtcactgc atagcgttcg ctaccacgcg ctttgcgatt ctgcattgtc
     4441 agccagaatg cgtagataat gtgaattacg aaaagagcag ccagtcctgc ggtagccact
     4501 aatgcatacc agtttgctcc caggaactca caaatcatgt tgtaaccatc agccgagatg
     4561 atcgcaacca agttcatcgc catgtgaaat gttagaaaca ggacaagggc gataccggta
     4621 acgctcatca ccactttcct tcctacagat gaattactta accacataaa tgattgaatt
     4681 taaattattt aattgttaga actaaaattt cgacgtttta cacctcttac ggactgcaaa
     4741 aataggggaa atagattgat tgagcaagga attaaagaaa taattcttta ataatggatc
     4801 aatacgccaa tgtgtcaata tgccagccag tatgcgcgca tggtgcaact gattggcaca
     4861 ttcgtaggat gggactgttt attgtacctt tccgattttc tcaccgccgg ctgctttttt
     4921 gcgtaaagcg cgtggggtat cgccgaaaga gtctttacag aagtgtgcga aatgtgacag
     4981 ggagtcgaat ccgtatttgt tacagatttc agtgattcgc attttgctgt gttgcaggtc
     5041 ttccaggatt ccttcccgtt tcttttccag tatccattca tatacgggca taccatacag
     5101 gtttttgaag aggcggcgga aagtagtggt cgtatatcct cccaggtgtg caaattcttc
     5161 tacgttcttc acgttgctgt agttttgcat gacgaagtag tggaaacttt ccgtatatgt
     5221 gctgattgga tagaagaatg agcttagctg gggtagcggg tagaaattgg taatcaagaa
     5281 aactaattcc ttgcatttta agttgatata cttgctgcaa ggggtttcct caccgaggaa
     5341 ttcgggcata ctggtgacaa gatggtacag tctttcactc atgacaagcg gagtgtaggt
     5401 caatggggct cctgtctgtt ccatcatttc tttgtaccgt tcttcgcaga gcagaggtag
     5461 ttcgttgaac caatagacaa catattcaac atctgtcagt gccaatattt caaccttgga
     5521 accgatagct tgcaggataa actgtttttc gcgcagtgta tttccgggat attcttcgct
     5581 gttgatcagt aattcaccct ttatcataaa aagcatacaa ttctgcgtac acttatcctt
     5641 ggggatatgc tctcctttgg gtaaatttct atatacaagg atattctcag tggctttggg
     5701 gcatcccgta cagttggtat attgtatgca aaatgaatct cctggcatga gttttattca
     5761 tgatttatta tcttgacgga acaaagatag actttttttg tggaaaatgg aattctttct
     5821 tttatttatg ttttagtaga aatctttgta tgattatctt tgatgtagtg gaatgaattt
     5881 ataactaata tattgtatcg ttccagccta ttcagacagt agataattct caccgtgatg
     5941 agaaataatt ctcaatgcga tgagaaaatt ttctcaccac gatgagtatt ttttctcatc
     6001 acggtgagaa ttatttgaga aaataaggaa tggaaaagca acataaaaag ttttcaagga
     6061 gagtatggcg gtatgattac cgcatgtcct tattataata cttttcgagt aattcctgca
     6121 tctccggata tttctcgtct gtatcaccta cttccttgcg gagatttaat aattgctttt
     6181 tcatctgttt gatgacaggg gcgtacttcg gatcattgta tgcattatga ttttcatgcg
     6241 ggtcgttttg taaatcatag aagtcccatg acggagtgaa ttcaaagttt cctgtatcgg
     6301 tcatatccag attttgagcg taatagaaga tcagtttgta tcgatcggac cggatggcga
     6361 aatgtgccgg gcgtatggca tgattggtcc agtatcggta atagatttcc tttctccagt
     6421 cgggtggagt ctttccttcg aggttgttga cgaaactggt tccttgcaca ttctccattt
     6481 ttactccggc aaattcggct agagttggtg cgaaatcgac gttgagtatc aggtctttca
     6541 ggcgttctcc agcagggatc tttttgggat agcggataac gaaaggcata cgggctgatt
     6601 cttcataaaa catacgtttg tcgaagaagc catgttcgcc caggaaatat ccctgatcgg
     6661 agacgtagac aactattgta ttatcagcaa tacccatttc atcgagagtt ttcaggagct
     6721 tgccgatatt gtcgtcaaca gtggctccgc aacgcatata atcgcggatt agtttttgat
     6781 aggctgcgcg tctggcggtg gttcgttgca ttccttccgt actgaacggc agaccgggat
     6841 aacgacacca ccacttatcc ggatcttttg aggcgatttt ccagcggcgt accaactctt
     6901 ctaagggttg ccctttgaaa gaacgcccgt tggtttccgg tccccagtcc agaagatttt
     6961 ccggttcggg gaaggtgaca tcgtcgtaaa gatgttccat acgaatcgga taatcgtagg
     7021 gttcgtgagt ggctttgaag tggcagcaca tcaggaaagg ttgcttgccg tcctgttgct
     7081 tgatccagtt gattgctttt tctgtgacga gatcggtaga aaagccaagt atgcgttctc
     7141 caaatcgtcg gttacccggc cagggatcac tactttcgat aaaagtggga tcacgatatt
     7201 ctccctggtc gtagaagata gagtaataat tgaagccctg tggctgtgac ttgatatgcc
     7261 atttcccgac aagccctgtg ttatatccat gtgattgtag aacggtagcc agggtgggga
     7321 ttgaagtgtt caaagaatcg gctagtgtgt aaagtccgtt ccggtggcta tataatcctg
     7381 taaggatact ggcacggctg ggtgcggaga tggaattagt acagaaacaa ttatcgagga
     7441 ctacgccttc attggcaagt cggcgaatat tgttattata ggcataatct gccagcactc
     7501 caccataaat gccccatgct tgtgaggtgt ggtcgtcact taggataaag aggatattgg
     7561 gacgctgttc gtccttttgt tggtttcctt gcccggcagt agtttgggca cttaaattgt
     7621 ggatggctgc tccggcagtt aaaaatccgg ttaatagtaa tttattcata aatatagatt
     7681 tgttgtattt ctttgaacgt gagtttgtga caatatttca gctaccaatt gagtagctga
     7741 aattacaaag aaacgtactt tattttattt tttctaactc ttttttcaag atttgtctgt
     7801 ttttgtgtct gaatggaaga ctttatgttg atttctggaa gtattatagt tgtttttgaa
     7861 catctatttc cgtttgacat gcgtattttt gcgatctaaa cttattaatt atcaatcatt
     7921 atgctaatgc taagaaaaat tgtattcttc ctttttttgt ttgtcggatt atcattattt
     7981 gcacaacaag actatatgat cagttcttat gtgcggggta atttttacaa tcgagggcgt
     8041 atttctacag aaagctgcgg gcaagtgacg atctaatctt tttgagtgtt caccctaata
     8101 aagacggatc gcttttattt gagaatcccc gtgcttttca gggaaaaggt gagacaactt
     8161 gggaagggtt gattaagtcg gttcgtggaa aagtaaaagg gacaaaagcg aaaatacgct
     8221 tgggtgcttc cagtggtgaa tggaaagcaa tggtggctga tgaggctgct cgtactacat
     8281 ttgcgaagaa tatcaagaaa gtgctggaaa agaataattt ggatggtatt gaccttgact
     8341 ttgaatgggc ggagaatgag aaagagtatg aagactatag tttggctatc ctgaagatgc
     8401 gggaagtctt gggagataag tatcttttca gtgtatctct gcatcctgtt tgctataaga
     8461 ttagtaagaa agctattgaa gctgttgatt ttatttcact tcagtgctat ggcccttcac
     8521 cggttcgctt tccaatagag aaatattgtt cggatataca gatggtattg gagtatggta
     8581 ttccgaagga aaaactggta gccggggttc ctttttatgg tgtgactaaa gataattcaa
     8641 agaagacgga ggcctatttc aattttgtac aggatggact gattacgagt ccttcacaga
     8701 atgaggtgat atatcaggga gatacttatg tgtttgatgg tcaggataac attcgtatca
     8761 aaacccgtta tgcaaaagaa caaaaattga aaggcatgat gagttgggat ttggctacgg
     8821 atttgccgtt aaatgacagc aagtcattac taaaaacaat gactgaagaa ttgaggaaat
     8881 gacttagctc tcacggacac aggttgtacc ttttcttttt gtagatgcta tttaacggat
     8941 tcagttttaa tagattcccc tctccttata taaatcagat ttataaaatg cctcctaaaa
     9001 gttttgtatt aaacttttaa gaggtacttc tttttgggca ggagcaaaat tcgtttttta
     9061 aaacgtatga aacgtaagcg gcttccctct ttttatgatt gtataatctg cttcaggtaa
     9121 tccgaaggcg agacgccgaa ttcttcttta aagcattggc ggaaatatcc cgtactgttc
     9181 attcctactt tataggcgat ttcagagata ttgaactttc cttcaagcag taaacgttcg
     9241 gcattctgca ttttcacttt ccggatatat tcgttagtcg ataatcccgt tagtgctttc
     9301 attttccggt agagagtgga gccgctcata cacattttgt ctgaaagata ggtaatatca
     9361 atcttctccg aagagaggtt ttcttcgatt aaaagggtga ttttttcaat aaattcatta
     9421 tccagcttgc ttagagcttc ggcgattacg atacgttttt cttttaaatc tgcctgattg
     9481 cccggaacgg attgtgtctg gaattgagct atcagtttct ttcttgattc cagcagatta
     9541 ttgatacggc tgcgtagcag agaagcactg aaaggctttg tcagataaga atcggctcct
     9601 acctcgtatc cttcttcttt atcttgcaga gaatctttgg ctgtcaatag gatgacaggg
     9661 atatgactgg ttcgtacgtc ttctttcaat tgccggcaga gagtgatacc gtctatgaca
     9721 ggcatcataa tatcgctgac tacaatatct gggatgcggc taagagcttg ttgcttccct
     9781 tcttctccat tgtaggcggt gagtacttcg aacgaatcga caaaggactc ggcgatatat
     9841 ttctgtatct cttcattgtc ttctacaatc aacaggattg gtttgccggt atccagtgtg
     9901 gtttcttgtg gatattcaag gcttgcttcc gggttcgtct cctcttgaac cggttctgta
     9961 gaatctgcgt gtaaggcatt gggatagata ttatccgtca ataagctgat atagaatgag
    10021 cttccttcgt tttgtatgct ttctgcccgg atttctcctt catgcagggt gaccagattc
    10081 ttcaccaaag ccaaaccaat gcctgtgccg gatgcctgat gcttgccgct ttcctgataa
    10141 taacggtcaa aaatatgtgg cagggcttca gcagaaattc catatcccgt atcacttact
    10201 tttatctctg tataagctac ttcattacgc attgtctgat acaaacttag agtgacgcgc
    10261 ccttgttccg tatatttgat tgcgttggaa ataagattat ccaaaacaat ggtaatgatt
    10321 tccttatcga aaaaaagaaa catttcttct ttctctattt gaatctggaa gtcaatcttg
    10381 gtcttttgat ttagttcttt gtatttaagt cctatctcat aaatcaaagg agcgatattg
    10441 cctttgctga cgcacaattt cttattttgc gtctctgtct ttcggaattc cagtatttgg
    10501 ttaatcaagt tgagcagccg tagcgcactt tgatggatga cagataactt ctgggcttgt
    10561 tttgccggaa gtgaggtttc tttttgcata tcttccaagg gaccgaggat taaggtcaac
    10621 ggtgtacgta gttcatgggt gatattggtg tagaaccgca gacgttcctg attcaattcc
    10681 tgttcctgct catggttttt cttttccaaa atatagaggc tttctaaatc cagcttcttt
    10741 ttatatgcat gcaagataag ataaatgatg ctgatagata ctaaaatata gataagcttt
    10801 gcccaccacg tcagccaaag agggggattg acacggatgg taagtgaagt agcttcttcc
    10861 ggccattctt ggttatgtac tcgtgctttg atgaggaact catattttcc cggaggaatg
    10921 tttcggaaag tgacactgtt gttctcattg acggtgtacc atgagttctc aagccctttc
    10981 agcatataaa catactccac ttggttgaca agtgagtagt tttgcacatt aaatgtaagt
    11041 ccaaagctat tttgcgcatg acttaattct acattctgtc ctttggacaa gttgataatc
    11101 atgtcgttat tttccagatt gctcaatcgt cccagtattt tcatttccgt gataactgct
    11161 accggagtag gttgttcatt cattgtaata tcaggattaa aacaacatac tccattgata
    11221 gaaccgaaat aaatccatcc gttcttgttt tgcgttacac aaccgcttga gaaacttccc
    11281 gccggaacat cgtcagaatg accatagtga tagaaacaat ctttggctgt cacgtagcag
    11341 ctgacacctt tattattgct aaaccatata ttacctttct tgtcttctgt tattgcacag
    11401 atatttgtat tggttaaacc atcttttcgt tgatatgttt tgtaggttaa tacattggtt
    11461 gaaggaaaac agactagtcc ttctcctgtc cctatccaca ttcttttgtg tttatcctgt
    11521 atgatctgat tgacggtatt ggaacagaag ccctcccttt ggacaaaggt cttgatttgt
    11581 tgtagatcgg gcgtgtatac gccaagtccg tctccgaagg tcccaatcca gaaacgccct
    11641 ttctcatctt gagctataga acgtacaaaa tcactgtgta gttcgctgtt ttcagtgttg
    11701 tagtgtcgga taatttccat gttgagggga ttcaatacaa tgattcctcc gctatatcct
    11761 acccagatat tatgttgagt atcttcgtag atcgtacgga catcctgatt gtactgtccc
    11821 atgagggaga tggaacgaaa ccttttattc cgagtgtcat aataactgat tcctccttga
    11881 aaagaaccga accatagatt tccttttgaa tcctgtaaag aggtcaatat gaaattggaa
    11941 gggatgtctc cagtctcttt tttataaata gcaatacgct tgtccccttc aaatacattg
    12001 ataccacctc cgtctgttcc aatccatata cgtccttgtc tgtcggtaca gagactgctt
    12061 gcaactttat tgttcagact gttttcattg ttgggaatcg gagaataact taatgttgtg
    12121 aataagggtg gctttctgct gataaagttg attcctcctc cccatgtacc tatccagata
    12181 ttgtcaaaag aatcttggaa tatacaccgg gcacttgcat tggaaaggct tcgactatca
    12241 tcaccttcct gaatatattc gagggaaatc tgttcgggtg agagaaacat actttgtttg
    12301 agatccagta tagtaatgcc attaagttcg gaagcaatcc aaagtttacc gtcgtttaat
    12361 tgtttaatag ccaatatccg attgcataaa gcagcatatt tatcattttt gttattctta
    12421 aaagtgataa agctttgatc ggtagcattg aaaagagcca ggcctttatc tgtccctagc
    12481 catatattac cgtttgtgtc tttagtgaga catcgtacat cattaccggg caggctcttc
    12541 gggtcgtccg aatgattctg gaagtttttt acacttttat ctttgagaga aagaatactg
    12601 aatccgtggc cgacatggcc gatgtataga ttcccgtctc ctccgtccaa cacagtccat
    12661 gtttgttcac aagataaggc gggcactgta ttcttgttat aatgagtgaa ctgcccactg
    12721 ttaatgtcga gatattctat acctctatag taagtactga tccacaagcc atcttcatgt
    12781 tgagcagaag gagcgatgtc cgttacgtca ttcgtaatta ggctatgagg gtcatccgga
    12841 ttatgtgaat aagctgtaaa tacctgtttg ttgtaattat atgcatttaa tccgtcccgt
    12901 tgagtcgcta tccatataat gggacgttta ttgtcagcat atacccgatt gagttcattg
    12961 ccagtgattc cctggctact ttgcgataag tcattcttat aataggtcat gaaacgggtc
    13021 ccgtcgaatt tattaagtcc ttcttccgta gcaaaccata agaagccttg tttatcttgt
    13081 gcgatactaa tcacataatt attagataat ccctgctcaa tacccaatcg tttgatagaa
    13141 tgggattgag ctatcaattg agaaactgat agcagacaca gaaagaaaat agaagtaatg
    13201 tgtttcttca taactcgtac ttattcgttt catttacaag ctcaaaaata ggaataaata
    13261 ttttatttag agtatgtaaa tcgtgcattg cacgatttat gtagcttctc tgcatgattt
    13321 ttgtcggttt atatagttgg aatcgtctac atttgtgatg tcgatttgcc gatattttat
    13381 atattgagaa gtcgtaccga gataatatta atcattaaat actaattatt atgaaagcta
    13441 aattgttgca aagcacggtt ttgtggactt tcctttcagt agcgaccttg ttggttggat
    13501 gtagtgacga tgaggattat agagatgtag acggacaatc tccaactctt gaattaacat
    13561 ctgatcatat ccgtacattg acaggctatg aattcaaaat tgcaggtaaa attgtggata
    13621 aagatggtat tcgttctatt aatctacaat gtgcagagct ttacttggac aagacaattg
    13681 aattgttaac tctttattca gaatcattgt atgagtataa tctgaattat ggtttcacta
    13741 ttcctgaaaa aacaaaaggt gacagtttta ctataaaggt aacagttaca gatttaggtg
    13801 ggcgtacagc aacaagcgat gtcctgatta cgatggatgg tgattataca gaaccagtct
    13861 tgactccgtc tattggtctt ttaagtgata atattaatat agtgttgtct gaaggcactt
    13921 ctaaaacatt ccggttcact gcacaagata ataaggaatt ggattatctg gaattggctg
    13981 ttcctgattt ggaaatcttg gaacgtctgg atattgaaga aggagagaaa aaaggaacat
    14041 tgaatactac tgttgtattt ccttctgata agactgggac ctatacgttg gttatacgtg
    14101 ctgttgatac ttttggcaat gttgcggaaa agaactattc agtactcgtt tccagagtga
    14161 aagattatga gaatatgtat ctggttgatt ttgaaggaac agacagcaaa ttgctaacag
    14221 gtaatgacgt atggggagtt ccaatgccta tagaacgagt aacgaatttc acctataagg
    14281 ctcgttgtta ttcacctgct ccaaataccc caatccgttt cattacaagc aaatatagtt
    14341 ttagcatctg ttttggtgat gacaaaaata atccgggaaa actaactggc atttctgaag
    14401 atgtacagcc gattattcta cctgaaaaga gctattatga aataaacttt aatacagaag
    14461 aaggaaccta tacagtagaa gcttattctc cgggaacacc aattattgac ggacttaaaa
    14521 tgggattcgt tggcggatgg tttgatggtg ccaaaggctg ggacggacct aagaatgtct
    14581 atgaattgac tcaagatccg gataatccgc attgtctcac agcagaattg acttggagta
    14641 aacaagattc ttttgacgtg acaatca
//
