## Wed Jun 26 19:25:59 2024
## emapper-2.1.12
## /d223NFS/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /d223NFS/m128030014/NGP/gene_list/prokka_results/GCA_003474885.1/GCA_003474885.1.faa --temp_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_003474885.1/2.eggNOGmapper --output_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_003474885.1/2.eggNOGmapper --output eggNOG_out --override --cpu 20 -m diamond --sensmode fast
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
PNCOCPKN_00002	138119.DSY1048	6.92e-05	44.7	COG0640@1|root,COG0640@2|Bacteria,1V6Z2@1239|Firmicutes,24JUM@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, ArsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
PNCOCPKN_00003	397288.C806_04878	8.12e-10	56.2	COG3668@1|root,COG3668@2|Bacteria,1VD9X@1239|Firmicutes,24I2T@186801|Clostridia,27PF8@186928|unclassified Lachnospiraceae	186801|Clostridia	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K19092	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
PNCOCPKN_00004	397288.C806_04879	8.06e-55	172.0	COG3077@1|root,COG3077@2|Bacteria,1VGJW@1239|Firmicutes,24JNU@186801|Clostridia,27U7S@186928|unclassified Lachnospiraceae	186801|Clostridia	L	RelB antitoxin	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
PNCOCPKN_00005	742735.HMPREF9467_04136	2.35e-64	197.0	COG2963@1|root,COG2963@2|Bacteria,1V6RE@1239|Firmicutes,24P5I@186801|Clostridia	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
PNCOCPKN_00006	1280698.AUJS01000133_gene2149	1.6e-170	481.0	COG2801@1|root,COG2801@2|Bacteria,1TRV8@1239|Firmicutes,24BSY@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
PNCOCPKN_00007	994573.T472_0216495	7.78e-168	484.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,36F7Z@31979|Clostridiaceae	186801|Clostridia	L	Reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
PNCOCPKN_00008	1235799.C818_02304	7.75e-102	308.0	2EXY8@1|root,33R7C@2|Bacteria,1VSYY@1239|Firmicutes,24ZGP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00009	1235798.C817_03255	7.73e-213	590.0	COG2378@1|root,COG2378@2|Bacteria,1TSA2@1239|Firmicutes,247S2@186801|Clostridia,27V61@189330|Dorea	186801|Clostridia	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
PNCOCPKN_00010	742740.HMPREF9474_02431	1.64e-149	431.0	COG5279@1|root,COG5279@2|Bacteria,1UT8R@1239|Firmicutes,24CQF@186801|Clostridia,21YP1@1506553|Lachnoclostridium	186801|Clostridia	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
PNCOCPKN_00011	471875.RUMLAC_02133	6.3e-105	305.0	COG0778@1|root,COG0778@2|Bacteria,1V4K6@1239|Firmicutes,24B09@186801|Clostridia,3WJCA@541000|Ruminococcaceae	186801|Clostridia	C	Nitroreductase family	nfrA2	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
PNCOCPKN_00012	1121115.AXVN01000043_gene3376	0.0	1240.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1TQ62@1239|Firmicutes,249TK@186801|Clostridia	186801|Clostridia	L	helicase	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,ResIII
PNCOCPKN_00013	1121115.AXVN01000043_gene3375	5.27e-98	289.0	COG2227@1|root,COG2227@2|Bacteria,1V1MT@1239|Firmicutes,24FTN@186801|Clostridia,3Y29B@572511|Blautia	186801|Clostridia	H	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,NUDIX
PNCOCPKN_00014	1408312.JNJS01000001_gene1400	4.51e-12	63.2	COG1051@1|root,COG1051@2|Bacteria,1UIGB@1239|Firmicutes,24NCA@186801|Clostridia,3NI5W@46205|Pseudobutyrivibrio	186801|Clostridia	F	NUDIX domain	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
PNCOCPKN_00015	1292035.H476_2740	7.04e-235	718.0	COG1474@1|root,COG1474@2|Bacteria,1UYHX@1239|Firmicutes,253TS@186801|Clostridia,25T19@186804|Peptostreptococcaceae	186801|Clostridia	LO	the current gene model (or a revised gene model) may contain a frame shift	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00016	1235798.C817_03609	2.26e-89	263.0	COG3727@1|root,COG3727@2|Bacteria,1V3S8@1239|Firmicutes,24MYE@186801|Clostridia,27VT0@189330|Dorea	186801|Clostridia	L	DNA mismatch endonuclease Vsr	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DUF559,Vsr
PNCOCPKN_00017	1216932.CM240_1423	1.64e-41	139.0	2DXX2@1|root,3471B@2|Bacteria,1UQ8I@1239|Firmicutes,24T5P@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
PNCOCPKN_00018	180332.JTGN01000004_gene2249	1.06e-236	652.0	COG0270@1|root,COG0270@2|Bacteria,1TSNX@1239|Firmicutes,2490C@186801|Clostridia	186801|Clostridia	H	PFAM C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
PNCOCPKN_00019	1216932.CM240_1421	1.01e-106	321.0	COG3886@1|root,COG3886@2|Bacteria,1VDX4@1239|Firmicutes,24NKE@186801|Clostridia	186801|Clostridia	L	NgoFVII restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RE_NgoFVII
PNCOCPKN_00020	180332.JTGN01000004_gene2248	0.0	1021.0	COG0610@1|root,COG0610@2|Bacteria,1UIN3@1239|Firmicutes,25ENP@186801|Clostridia	186801|Clostridia	V	Z1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Z1
PNCOCPKN_00021	180332.JTGN01000004_gene2247	4.16e-232	644.0	2CXRX@1|root,32T2G@2|Bacteria,1VQWD@1239|Firmicutes,24988@186801|Clostridia	186801|Clostridia	L	NgoFVII restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RE_NgoFVII
PNCOCPKN_00022	585394.RHOM_09600	2.34e-253	697.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia	186801|Clostridia	C	Malic enzyme, NAD binding domain	maeB	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
PNCOCPKN_00023	585394.RHOM_09605	1.23e-168	477.0	COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,247U3@186801|Clostridia	186801|Clostridia	S	radical SAM protein, TIGR01212 family	ytqA	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
PNCOCPKN_00024	585394.RHOM_09610	3.79e-100	292.0	COG3432@1|root,COG3432@2|Bacteria,1V75P@1239|Firmicutes,24JAZ@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4364
PNCOCPKN_00025	585394.RHOM_09615	2.13e-116	338.0	COG1853@1|root,COG1853@2|Bacteria,1V1EA@1239|Firmicutes,24FWS@186801|Clostridia	186801|Clostridia	V	Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
PNCOCPKN_00026	585394.RHOM_09630	0.0	921.0	COG1164@1|root,COG1164@2|Bacteria,1TPV4@1239|Firmicutes,2495D@186801|Clostridia	186801|Clostridia	E	oligoendopeptidase, M3 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
PNCOCPKN_00027	585394.RHOM_09640	1.44e-116	353.0	28JJA@1|root,2Z9CD@2|Bacteria,1TPY4@1239|Firmicutes,24DSP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00028	585394.RHOM_03580	1.01e-167	478.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
PNCOCPKN_00029	585394.RHOM_03570	1.05e-214	596.0	COG1172@1|root,COG1172@2|Bacteria,1TPPT@1239|Firmicutes,248FJ@186801|Clostridia	186801|Clostridia	G	Belongs to the binding-protein-dependent transport system permease family	yjfF	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
PNCOCPKN_00030	585394.RHOM_03565	8.32e-220	610.0	COG1172@1|root,COG1172@2|Bacteria,1TR6F@1239|Firmicutes,2484T@186801|Clostridia	186801|Clostridia	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
PNCOCPKN_00031	585394.RHOM_03560	0.0	887.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia	186801|Clostridia	G	import. Responsible for energy coupling to the transport system	araG_1	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
PNCOCPKN_00032	585394.RHOM_03555	4.55e-212	592.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
PNCOCPKN_00033	585394.RHOM_03550	4.23e-241	675.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase
PNCOCPKN_00034	585394.RHOM_03545	5.95e-213	608.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
PNCOCPKN_00035	585394.RHOM_09645	0.0	927.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,2490X@186801|Clostridia	186801|Clostridia	E	'glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
PNCOCPKN_00036	585394.RHOM_09650	0.0	2846.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,248IB@186801|Clostridia	186801|Clostridia	E	'glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
PNCOCPKN_00037	411462.DORLON_00146	1.27e-28	109.0	COG2364@1|root,COG2364@2|Bacteria,1V19X@1239|Firmicutes,24DJ8@186801|Clostridia,27VXU@189330|Dorea	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00038	33035.JPJF01000073_gene4424	1.58e-19	86.7	COG2364@1|root,COG2364@2|Bacteria,1UXHA@1239|Firmicutes,24AJQ@186801|Clostridia,3Y0DC@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00040	742723.HMPREF9477_01251	5.02e-52	168.0	COG0454@1|root,COG0456@2|Bacteria,1VAFS@1239|Firmicutes,24MUI@186801|Clostridia,27NWY@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03826	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10,Acetyltransf_7
PNCOCPKN_00041	622312.ROSEINA2194_00096	2.34e-96	290.0	COG1266@1|root,COG1266@2|Bacteria,1V7EK@1239|Firmicutes,24KV5@186801|Clostridia	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
PNCOCPKN_00042	622312.ROSEINA2194_00090	0.0	1270.0	COG0188@1|root,COG0188@2|Bacteria,1TPNX@1239|Firmicutes,24ADK@186801|Clostridia	186801|Clostridia	L	COG0188 Type IIA topoisomerase (DNA gyrase topo II, topoisomerase IV), A subunit	gyrA_1	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
PNCOCPKN_00043	585394.RHOM_09675	0.0	1204.0	COG0187@1|root,COG0187@2|Bacteria,1TRSZ@1239|Firmicutes,247ZY@186801|Clostridia	186801|Clostridia	L	COG0187 Type IIA topoisomerase (DNA gyrase topo II, topoisomerase IV), B subunit	parE	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
PNCOCPKN_00044	585394.RHOM_09685	8.88e-220	611.0	COG3835@1|root,COG3835@2|Bacteria,1TQWD@1239|Firmicutes,24ZMW@186801|Clostridia	186801|Clostridia	KT	Psort location Cytoplasmic, score	-	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30
PNCOCPKN_00045	585394.RHOM_09690	1.56e-255	702.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	ugpC_1	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
PNCOCPKN_00046	1235793.C809_04227	1.07e-104	310.0	COG0300@1|root,COG0300@2|Bacteria,1TRP8@1239|Firmicutes,24DNY@186801|Clostridia,27N1X@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
PNCOCPKN_00047	585394.RHOM_12890	8.13e-152	437.0	COG1533@1|root,COG1533@2|Bacteria,1TPA3@1239|Firmicutes,249NM@186801|Clostridia	186801|Clostridia	L	Spore photoproduct lyase	-	-	4.1.99.14	ko:K03716	-	-	-	-	ko00000,ko01000	-	-	-	-
PNCOCPKN_00048	1235802.C823_04351	3.68e-60	201.0	COG0775@1|root,COG0775@2|Bacteria,1VCJY@1239|Firmicutes,24CRR@186801|Clostridia	186801|Clostridia	F	PFAM purine or other phosphorylase family 1	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
PNCOCPKN_00049	1235802.C823_02304	5.72e-83	247.0	COG0756@1|root,COG0756@2|Bacteria,1V5PP@1239|Firmicutes,24I3J@186801|Clostridia,25W99@186806|Eubacteriaceae	186801|Clostridia	F	dUTPase	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
PNCOCPKN_00050	585394.RHOM_09700	3.11e-211	587.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia	186801|Clostridia	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
PNCOCPKN_00051	585394.RHOM_09705	5.58e-125	359.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
PNCOCPKN_00052	585394.RHOM_09710	7.84e-301	822.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
PNCOCPKN_00053	585394.RHOM_09715	4.45e-166	496.0	COG1277@1|root,COG1277@2|Bacteria,1TRJ8@1239|Firmicutes,24EMN@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
PNCOCPKN_00054	585394.RHOM_09720	1.56e-185	519.0	COG1131@1|root,COG1131@2|Bacteria,1TPQW@1239|Firmicutes,248F7@186801|Clostridia	186801|Clostridia	V	Abc transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PNCOCPKN_00055	585394.RHOM_09725	5.37e-57	179.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,24MTU@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, GntR family	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
PNCOCPKN_00056	622312.ROSEINA2194_00078	3.06e-208	580.0	COG1363@1|root,COG1363@2|Bacteria,1TQ86@1239|Firmicutes,25CDF@186801|Clostridia	186801|Clostridia	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
PNCOCPKN_00057	622312.ROSEINA2194_00077	5.4e-146	419.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,248TD@186801|Clostridia	186801|Clostridia	L	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
PNCOCPKN_00058	622312.ROSEINA2194_00076	1.71e-55	175.0	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia	186801|Clostridia	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
PNCOCPKN_00059	585394.RHOM_09750	5.68e-49	157.0	COG2257@1|root,COG2257@2|Bacteria,1VF4R@1239|Firmicutes,24QSW@186801|Clostridia	186801|Clostridia	S	cytoplasmic domain of flagellar protein FhlB	flhB1	-	-	ko:K04061	-	-	-	-	ko00000,ko02044	-	-	-	Bac_export_2
PNCOCPKN_00060	585394.RHOM_09755	1.69e-198	579.0	28J8T@1|root,2Z93Y@2|Bacteria,1UZBP@1239|Firmicutes,24F5R@186801|Clostridia	186801|Clostridia	S	Flagellar hook-length control protein FliK	-	-	-	-	-	-	-	-	-	-	-	-	Flg_hook
PNCOCPKN_00061	585394.RHOM_09760	4.84e-135	387.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
PNCOCPKN_00062	1235790.C805_02231	1.81e-74	229.0	COG0681@1|root,COG0681@2|Bacteria,1UZ8V@1239|Firmicutes,25CN7@186801|Clostridia,25WUU@186806|Eubacteriaceae	186801|Clostridia	U	Signal peptidase, peptidase S26	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
PNCOCPKN_00063	622312.ROSEINA2194_00072	5.56e-170	478.0	COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,2490H@186801|Clostridia	186801|Clostridia	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
PNCOCPKN_00064	585394.RHOM_09770	6.26e-110	319.0	COG0681@1|root,COG0681@2|Bacteria,1V2SF@1239|Firmicutes,24AWM@186801|Clostridia	186801|Clostridia	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
PNCOCPKN_00065	585394.RHOM_05525	1.14e-237	656.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia	186801|Clostridia	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
PNCOCPKN_00066	1034345.CAEM01000003_gene1256	7.26e-20	91.7	COG2199@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,2I49F@201174|Actinobacteria,4CUE6@84998|Coriobacteriia	84998|Coriobacteriia	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GGDEF,HD,Response_reg
PNCOCPKN_00067	397287.C807_03866	1.37e-71	227.0	28S3E@1|root,2ZEF6@2|Bacteria,1V25C@1239|Firmicutes,24GTH@186801|Clostridia,27KYG@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00068	471875.RUMLAC_02383	1.14e-236	660.0	COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1TNZH@1239|Firmicutes,24BQZ@186801|Clostridia,3WHBW@541000|Ruminococcaceae	186801|Clostridia	S	Putative threonine/serine exporter	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
PNCOCPKN_00069	585394.RHOM_01185	3.61e-243	676.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
PNCOCPKN_00070	411461.DORFOR_01502	1.85e-114	335.0	28JZH@1|root,2Z9PI@2|Bacteria,1V0QF@1239|Firmicutes,248FG@186801|Clostridia,27WS8@189330|Dorea	186801|Clostridia	S	Domain of unknown function (DUF4866)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4866
PNCOCPKN_00071	585394.RHOM_01170	7.12e-124	357.0	COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes,24DUE@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
PNCOCPKN_00072	742765.HMPREF9457_00204	5.61e-143	410.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia,27VZT@189330|Dorea	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PNCOCPKN_00073	622312.ROSEINA2194_03509	1.74e-207	577.0	COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,2486N@186801|Clostridia	186801|Clostridia	S	Belongs to the binding-protein-dependent transport system permease family	tsgC13	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
PNCOCPKN_00074	622312.ROSEINA2194_03510	6.83e-214	596.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,2494C@186801|Clostridia	186801|Clostridia	S	Belongs to the binding-protein-dependent transport system permease family	tsgB13	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
PNCOCPKN_00075	622312.ROSEINA2194_03511	0.0	885.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia	186801|Clostridia	S	Abc transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
PNCOCPKN_00076	622312.ROSEINA2194_03512	1.06e-236	659.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248IH@186801|Clostridia	186801|Clostridia	S	ABC-type transport system, periplasmic component surface lipoprotein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
PNCOCPKN_00077	585394.RHOM_05520	1.54e-114	345.0	COG0628@1|root,COG0628@2|Bacteria,1TS4S@1239|Firmicutes,248E5@186801|Clostridia	186801|Clostridia	D	Sporulation integral membrane protein YtvI	ytvI	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
PNCOCPKN_00078	585394.RHOM_05505	5.63e-208	580.0	COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,248JF@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
PNCOCPKN_00079	622312.ROSEINA2194_01040	5.72e-280	767.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,248I3@186801|Clostridia	186801|Clostridia	O	peptidase U32	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
PNCOCPKN_00080	622312.ROSEINA2194_01039	1.34e-123	355.0	COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,24B70@186801|Clostridia	186801|Clostridia	S	O-methyltransferase	yrrM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
PNCOCPKN_00081	585394.RHOM_05490	4.65e-55	178.0	COG1559@1|root,COG1559@2|Bacteria,1VGA6@1239|Firmicutes,24RBR@186801|Clostridia	186801|Clostridia	S	YceG-like family	-	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
PNCOCPKN_00082	622312.ROSEINA2194_01037	8.21e-47	153.0	COG3679@1|root,COG3679@2|Bacteria,1VH19@1239|Firmicutes,24RNC@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0342 family	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
PNCOCPKN_00083	585394.RHOM_05485	0.0	1020.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
PNCOCPKN_00084	622312.ROSEINA2194_01035	2.38e-36	124.0	2E3Y4@1|root,32YV4@2|Bacteria,1VFRH@1239|Firmicutes,24QXW@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
PNCOCPKN_00085	622312.ROSEINA2194_01034	3.21e-86	255.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia	186801|Clostridia	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
PNCOCPKN_00086	622312.ROSEINA2194_01033	3.2e-53	167.0	COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,24QVQ@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0297 family	yrzL	-	-	-	-	-	-	-	-	-	-	-	DUF965
PNCOCPKN_00087	585394.RHOM_05465	3.92e-254	704.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia	186801|Clostridia	J	MiaB-like tRNA modifying enzyme	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
PNCOCPKN_00088	585394.RHOM_05460	4.54e-45	145.0	COG1925@1|root,COG1925@2|Bacteria,1VAQP@1239|Firmicutes,24N19@186801|Clostridia	186801|Clostridia	G	phosphocarrier protein HPr	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
PNCOCPKN_00089	585394.RHOM_05455	6.5e-269	738.0	COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,247Y5@186801|Clostridia	186801|Clostridia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
PNCOCPKN_00090	585394.RHOM_05450	1.21e-219	612.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
PNCOCPKN_00091	585394.RHOM_05445	1.03e-108	321.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
PNCOCPKN_00092	585394.RHOM_05440	5.11e-219	606.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia	186801|Clostridia	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
PNCOCPKN_00094	622312.ROSEINA2194_01127	1.66e-153	434.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia	186801|Clostridia	E	abc transporter atp-binding protein	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
PNCOCPKN_00095	585394.RHOM_05430	4.18e-267	743.0	COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TPM3@1239|Firmicutes,248UY@186801|Clostridia	186801|Clostridia	P	Abc transporter	ArtM	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
PNCOCPKN_00096	585394.RHOM_04995	3.06e-118	345.0	COG0775@1|root,COG0775@2|Bacteria,1TSB7@1239|Firmicutes	1239|Firmicutes	F	COG0775 Nucleoside phosphorylase	-	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
PNCOCPKN_00097	622312.ROSEINA2194_01130	9.3e-102	295.0	COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,24G3R@186801|Clostridia	186801|Clostridia	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
PNCOCPKN_00098	1173026.Glo7428_1322	1e-51	178.0	COG0657@1|root,COG0657@2|Bacteria,1G229@1117|Cyanobacteria	1117|Cyanobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
PNCOCPKN_00099	457412.RSAG_01565	9.84e-131	372.0	COG0560@1|root,COG0560@2|Bacteria,1TQJY@1239|Firmicutes,2493S@186801|Clostridia,3WH3X@541000|Ruminococcaceae	186801|Clostridia	E	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein	thrH	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD,Hydrolase
PNCOCPKN_00100	140626.JHWB01000019_gene917	2.09e-24	103.0	COG2214@1|root,COG2214@2|Bacteria,1V4YZ@1239|Firmicutes,24U0J@186801|Clostridia	186801|Clostridia	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00101	1280694.AUJQ01000005_gene1348	5.3e-66	228.0	COG3437@1|root,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,3NGP7@46205|Pseudobutyrivibrio	186801|Clostridia	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,HisKA_7TM
PNCOCPKN_00102	585394.RHOM_05295	9.28e-272	746.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,24969@186801|Clostridia	186801|Clostridia	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
PNCOCPKN_00103	411474.COPEUT_00135	1.26e-85	268.0	COG1670@1|root,COG3393@1|root,COG1670@2|Bacteria,COG3393@2|Bacteria,1V1G4@1239|Firmicutes,24G4Y@186801|Clostridia	186801|Clostridia	J	Acetyltransferase, gnat family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
PNCOCPKN_00105	585394.RHOM_09775	7.46e-72	216.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
PNCOCPKN_00106	622312.ROSEINA2194_00064	4.53e-145	412.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
PNCOCPKN_00107	622312.ROSEINA2194_00063	1.42e-97	286.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia	186801|Clostridia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
PNCOCPKN_00109	585394.RHOM_09790	9.6e-38	127.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
PNCOCPKN_00110	622312.ROSEINA2194_00061	1.71e-49	157.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
PNCOCPKN_00111	622312.ROSEINA2194_00060	3.66e-271	748.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
PNCOCPKN_00112	585394.RHOM_09805	1.83e-62	193.0	COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,24QNM@186801|Clostridia	186801|Clostridia	S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein	-	-	-	ko:K09787	-	-	-	-	ko00000	-	-	-	UPF0122
PNCOCPKN_00114	585394.RHOM_09820	4.35e-265	729.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia	186801|Clostridia	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
PNCOCPKN_00115	622312.ROSEINA2194_00054	3.1e-199	555.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
PNCOCPKN_00116	585394.RHOM_09830	0.0	1573.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
PNCOCPKN_00117	622312.ROSEINA2194_00051	1.2e-129	372.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
PNCOCPKN_00118	585394.RHOM_09845	1.51e-41	137.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
PNCOCPKN_00119	622312.ROSEINA2194_00049	1.1e-220	612.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
PNCOCPKN_00120	585394.RHOM_09855	5.01e-80	247.0	COG5578@1|root,COG5578@2|Bacteria,1V91Z@1239|Firmicutes,24KZS@186801|Clostridia	186801|Clostridia	S	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
PNCOCPKN_00121	585394.RHOM_09870	5.07e-39	129.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,24QM0@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
PNCOCPKN_00122	622312.ROSEINA2194_00046	5.07e-95	280.0	COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia	186801|Clostridia	S	acr, cog1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
PNCOCPKN_00123	585394.RHOM_09880	2.1e-255	704.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia	186801|Clostridia	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
PNCOCPKN_00124	622312.ROSEINA2194_00044	2.88e-133	397.0	COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,247UP@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0348 family	-	-	-	-	-	-	-	-	-	-	-	-	HIGH_NTase1
PNCOCPKN_00125	585394.RHOM_09910	8.22e-269	737.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia	186801|Clostridia	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas
PNCOCPKN_00126	622312.ROSEINA2194_00040	2.45e-154	435.0	COG3363@1|root,COG3363@2|Bacteria,1TRA7@1239|Firmicutes,249ZW@186801|Clostridia	186801|Clostridia	F	IMP cyclohydrolase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	IMP_cyclohyd
PNCOCPKN_00127	585394.RHOM_09920	3.23e-137	405.0	COG4641@1|root,COG4641@2|Bacteria,1UYE0@1239|Firmicutes,24D1Q@186801|Clostridia	186801|Clostridia	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
PNCOCPKN_00128	585394.RHOM_09925	2.16e-300	822.0	COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,247K4@186801|Clostridia	186801|Clostridia	S	UPF0210 protein	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
PNCOCPKN_00129	585394.RHOM_09930	1.29e-50	161.0	COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,24QNV@186801|Clostridia	186801|Clostridia	T	Belongs to the UPF0237 family	-	-	-	ko:K07166	-	-	-	-	ko00000	-	-	-	ACT_6
PNCOCPKN_00130	585394.RHOM_09940	3.45e-156	442.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,249U2@186801|Clostridia	186801|Clostridia	J	Metallo-beta-lactamase domain protein	yycJ	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
PNCOCPKN_00131	585394.RHOM_09945	0.0	1013.0	COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,249Y7@186801|Clostridia	186801|Clostridia	D	cell division protein FtsA	ftsA	-	-	-	-	-	-	-	-	-	-	-	FtsA,MreB_Mbl
PNCOCPKN_00132	622312.ROSEINA2194_00035	1.12e-92	276.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,24GFQ@186801|Clostridia	186801|Clostridia	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
PNCOCPKN_00133	585394.RHOM_09955	0.0	1441.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
PNCOCPKN_00134	585394.RHOM_09960	0.0	1070.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia	186801|Clostridia	E	creatinase	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
PNCOCPKN_00135	622312.ROSEINA2194_00032	6.35e-100	290.0	COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,24NBX@186801|Clostridia	186801|Clostridia	S	acyl-CoA thioester hydrolase, YbgC YbaW family	FcbC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
PNCOCPKN_00136	622312.ROSEINA2194_00030	0.0	1007.0	COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,24BHM@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	GtrA,YfhO
PNCOCPKN_00137	585394.RHOM_05035	2.57e-283	795.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,2480C@186801|Clostridia	186801|Clostridia	M	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
PNCOCPKN_00140	585394.RHOM_11180	2.56e-77	258.0	2E03H@1|root,33IG6@2|Bacteria,1VKD9@1239|Firmicutes,24TED@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00141	585394.RHOM_11185	1.56e-308	842.0	COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,247JE@186801|Clostridia	186801|Clostridia	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
PNCOCPKN_00142	622312.ROSEINA2194_02991	4.2e-91	273.0	COG1595@1|root,COG1595@2|Bacteria,1TP55@1239|Firmicutes,249VX@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family	sigH	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	GerE,Sigma70_r2,Sigma70_r4_2
PNCOCPKN_00143	585394.RHOM_11195	6.6e-161	453.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
PNCOCPKN_00144	585394.RHOM_11200	3.62e-85	252.0	COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,24MR1@186801|Clostridia	186801|Clostridia	J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)	mrnC	-	-	ko:K11145	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Ribonuclease_3
PNCOCPKN_00145	585394.RHOM_11205	1.5e-312	855.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
PNCOCPKN_00146	622312.ROSEINA2194_02987	5.51e-143	406.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia	186801|Clostridia	E	serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
PNCOCPKN_00147	476272.RUMHYD_00828	6.04e-23	116.0	COG1657@1|root,COG2340@1|root,COG4886@1|root,COG5492@1|root,COG1657@2|Bacteria,COG2340@2|Bacteria,COG4886@2|Bacteria,COG5492@2|Bacteria,1UZVS@1239|Firmicutes,24DV2@186801|Clostridia,3Y094@572511|Blautia	186801|Clostridia	IN	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,Prenyltrans,SLH,SQHop_cyclase_C
PNCOCPKN_00148	622312.ROSEINA2194_00069	4.96e-81	254.0	COG1316@1|root,COG1316@2|Bacteria,1UY3P@1239|Firmicutes,24H37@186801|Clostridia	186801|Clostridia	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
PNCOCPKN_00149	1117315.AHCA01000004_gene745	2.64e-40	153.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RMA9@1236|Gammaproteobacteria,2Q1KV@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
PNCOCPKN_00150	1235799.C818_01516	9.68e-176	543.0	COG3210@1|root,COG3210@2|Bacteria,1UJX3@1239|Firmicutes,25FCY@186801|Clostridia,27IUC@186928|unclassified Lachnospiraceae	186801|Clostridia	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	fn3
PNCOCPKN_00151	622312.ROSEINA2194_02986	6.42e-106	308.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia	186801|Clostridia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
PNCOCPKN_00152	556261.HMPREF0240_01005	3.22e-121	365.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,36DFY@31979|Clostridiaceae	186801|Clostridia	L	domain protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,Lactamase_B
PNCOCPKN_00155	585394.RHOM_11225	0.0	1296.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,248JB@186801|Clostridia	186801|Clostridia	E	MeTHIonine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
PNCOCPKN_00156	622312.ROSEINA2194_01929	1.54e-231	640.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
PNCOCPKN_00157	585394.RHOM_11245	1.31e-75	237.0	COG1345@1|root,COG1345@2|Bacteria,1V9AS@1239|Firmicutes,24MHW@186801|Clostridia	186801|Clostridia	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00158	622312.ROSEINA2194_01931	7.45e-157	441.0	COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,247N9@186801|Clostridia	186801|Clostridia	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
PNCOCPKN_00159	622312.ROSEINA2194_01932	6.26e-169	473.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,24900@186801|Clostridia	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
PNCOCPKN_00160	622312.ROSEINA2194_01933	1.52e-116	336.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
PNCOCPKN_00161	622312.ROSEINA2194_01934	3.23e-43	166.0	2DM0G@1|root,31677@2|Bacteria,1UIGR@1239|Firmicutes,25EN6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00162	585394.RHOM_11275	3.8e-199	553.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1TRJU@1239|Firmicutes,24AQW@186801|Clostridia	186801|Clostridia	T	response regulator receiver	cheV	-	2.7.13.3	ko:K03407,ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,Response_reg
PNCOCPKN_00164	1235790.C805_02256	1.08e-26	110.0	2C0VN@1|root,32VTP@2|Bacteria,1VAWW@1239|Firmicutes,24N54@186801|Clostridia,25XSI@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4352
PNCOCPKN_00165	622312.ROSEINA2194_01937	1.78e-252	706.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
PNCOCPKN_00166	1235802.C823_02421	2.69e-136	389.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia,25UU1@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	srrA_6	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PNCOCPKN_00167	622312.ROSEINA2194_01939	6.29e-53	176.0	2DSWH@1|root,32UTX@2|Bacteria,1VBEP@1239|Firmicutes,24PR0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00168	1469948.JPNB01000001_gene964	2.52e-250	694.0	COG1501@1|root,COG1501@2|Bacteria,1UJ1V@1239|Firmicutes,24AVU@186801|Clostridia,36HI8@31979|Clostridiaceae	186801|Clostridia	G	Alpha galactosidase A	-	-	-	-	-	-	-	-	-	-	-	-	Melibiase_2
PNCOCPKN_00169	1469948.JPNB01000002_gene3625	0.0	1004.0	COG3533@1|root,COG3533@2|Bacteria,1TNYA@1239|Firmicutes,24841@186801|Clostridia,36FIY@31979|Clostridiaceae	186801|Clostridia	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
PNCOCPKN_00170	585394.RHOM_04085	0.0	1018.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,249UZ@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23,3.2.1.31	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01105,R01478,R01678,R03355,R04783,R04979,R06114,R07818,R08127,R08260,R10830	RC00049,RC00055,RC00171,RC00452,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
PNCOCPKN_00171	1469948.JPNB01000002_gene3623	2.38e-155	454.0	COG3507@1|root,COG5492@1|root,COG3507@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,Glyco_hydro_43,Laminin_G_3
PNCOCPKN_00172	1469948.JPNB01000002_gene3621	0.0	959.0	COG1874@1|root,COG1874@2|Bacteria,1TSHK@1239|Firmicutes,249IJ@186801|Clostridia,36E91@31979|Clostridiaceae	186801|Clostridia	G	Glycosyl hydrolases family 35	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_35
PNCOCPKN_00173	1280676.AUJO01000001_gene2223	2.74e-313	863.0	COG1653@1|root,COG1653@2|Bacteria,1TR5P@1239|Firmicutes,24F0C@186801|Clostridia,4C20R@830|Butyrivibrio	186801|Clostridia	G	Domain of unknown function (DUF3502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3502,SBP_bac_1
PNCOCPKN_00174	1280685.AUKC01000052_gene1365	5.86e-176	495.0	COG0395@1|root,COG0395@2|Bacteria,1TS9S@1239|Firmicutes,24BF3@186801|Clostridia,4BWPH@830|Butyrivibrio	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K17320	ko02010,map02010	M00207,M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
PNCOCPKN_00175	515622.bpr_I0935	2.16e-179	508.0	COG4209@1|root,COG4209@2|Bacteria,1TT63@1239|Firmicutes,25C4W@186801|Clostridia,4BW6J@830|Butyrivibrio	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
PNCOCPKN_00176	556261.HMPREF0240_00813	6.79e-122	361.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,248BZ@186801|Clostridia,36E93@31979|Clostridiaceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
PNCOCPKN_00177	1469948.JPNB01000002_gene3622	9.18e-203	575.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,36FU2@31979|Clostridiaceae	186801|Clostridia	V	Mate efflux family protein	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
PNCOCPKN_00178	1469948.JPNB01000002_gene3616	0.0	1002.0	COG3250@1|root,COG3250@2|Bacteria,1TPK7@1239|Firmicutes,247VE@186801|Clostridia,36FQM@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
PNCOCPKN_00179	658086.HMPREF0994_04316	2.07e-83	260.0	COG2207@1|root,COG2207@2|Bacteria,1UGXT@1239|Firmicutes,24EUQ@186801|Clostridia,27NK5@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
PNCOCPKN_00180	1226325.HMPREF1548_02854	1.91e-213	597.0	COG4225@1|root,COG4225@2|Bacteria,1TR4A@1239|Firmicutes,248Z1@186801|Clostridia,36F9Z@31979|Clostridiaceae	186801|Clostridia	S	Glucuronyl hydrolase	-	-	3.2.1.180	ko:K18581	-	-	R10867	RC00049,RC02427	ko00000,ko01000	-	GH88	-	Glyco_hydro_88
PNCOCPKN_00181	585394.RHOM_04080	0.0	912.0	COG3387@1|root,COG3387@2|Bacteria,1UI0N@1239|Firmicutes,25DI4@186801|Clostridia	186801|Clostridia	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_N
PNCOCPKN_00182	397288.C806_01728	0.0	1029.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,27J8N@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
PNCOCPKN_00183	585394.RHOM_11610	6.75e-271	744.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia	186801|Clostridia	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
PNCOCPKN_00184	537007.BLAHAN_06184	1.8e-186	520.0	COG2207@1|root,COG2207@2|Bacteria,1TXIY@1239|Firmicutes,248D1@186801|Clostridia,3Y2AU@572511|Blautia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
PNCOCPKN_00185	1235802.C823_01636	0.0	900.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,25V9R@186806|Eubacteriaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
PNCOCPKN_00186	411469.EUBHAL_01689	0.0	2071.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,25V34@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
PNCOCPKN_00187	1235798.C817_03206	3.22e-213	588.0	COG2207@1|root,COG2207@2|Bacteria,1TR2K@1239|Firmicutes,24ABH@186801|Clostridia,27W0B@189330|Dorea	186801|Clostridia	K	AraC-like ligand binding domain	araC_2	-	-	ko:K02099	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18,HTH_AraC
PNCOCPKN_00188	1235790.C805_00155	6.17e-145	414.0	COG1396@1|root,COG1396@2|Bacteria,1VF0W@1239|Firmicutes,24R43@186801|Clostridia,25XCU@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PNCOCPKN_00189	411483.FAEPRAA2165_03328	0.0	1071.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3WG90@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
PNCOCPKN_00190	1232443.BAIA02000081_gene858	3.82e-35	119.0	2C3T4@1|root,32S28@2|Bacteria,1VB78@1239|Firmicutes,24NAY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00191	742765.HMPREF9457_03186	0.0	933.0	COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,2495S@186801|Clostridia	186801|Clostridia	L	Virulence-associated protein E	-	-	-	-	-	-	-	-	-	-	-	-	VirE
PNCOCPKN_00192	585394.RHOM_06490	0.0	866.0	COG1196@1|root,COG1196@2|Bacteria,1TPU3@1239|Firmicutes,248HY@186801|Clostridia	186801|Clostridia	D	MobA MobL family protein	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
PNCOCPKN_00193	411463.EUBVEN_00971	4.84e-73	219.0	292P2@1|root,2ZQ6W@2|Bacteria,1V5SS@1239|Firmicutes,24HCY@186801|Clostridia,25YKF@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3847
PNCOCPKN_00194	1121115.AXVN01000087_gene4062	1.63e-43	141.0	2CBNR@1|root,32T16@2|Bacteria,1VA97@1239|Firmicutes,24NAW@186801|Clostridia,3Y0QV@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00195	1232443.BAIA02000081_gene862	5.8e-47	150.0	COG3311@1|root,COG3311@2|Bacteria,1VBZW@1239|Firmicutes,24P8G@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
PNCOCPKN_00196	411463.EUBVEN_00967	4.74e-261	714.0	28J8P@1|root,2Z93T@2|Bacteria,1UW2C@1239|Firmicutes,24AZ0@186801|Clostridia,25Y8H@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00198	1235798.C817_02752	0.0	1456.0	COG0577@1|root,COG0577@2|Bacteria,1TQ8P@1239|Firmicutes,25E38@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
PNCOCPKN_00199	1235835.C814_02689	7.43e-152	427.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,3WG7X@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PNCOCPKN_00200	500632.CLONEX_00661	1.53e-52	165.0	2C2RR@1|root,31NFE@2|Bacteria,1V905@1239|Firmicutes,24KRG@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00201	500632.CLONEX_00660	4.34e-90	264.0	28NTX@1|root,2ZBSD@2|Bacteria,1V1TV@1239|Firmicutes,24G4A@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00202	585394.RHOM_06455	1.89e-231	639.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PNCOCPKN_00203	411483.FAEPRAA2165_02282	1.51e-164	461.0	COG0745@1|root,COG0745@2|Bacteria,1TQRT@1239|Firmicutes,249PK@186801|Clostridia,3WHK5@541000|Ruminococcaceae	186801|Clostridia	K	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PNCOCPKN_00204	742765.HMPREF9457_03196	1.17e-18	77.0	COG2944@1|root,COG2944@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_31
PNCOCPKN_00205	411470.RUMGNA_01492	9.52e-16	78.6	COG1959@1|root,COG3437@1|root,COG1959@2|Bacteria,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,3Y0HN@572511|Blautia	186801|Clostridia	KT	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,Response_reg,Rrf2
PNCOCPKN_00206	1121115.AXVN01000132_gene727	4.8e-14	68.6	2CUHA@1|root,30KV1@2|Bacteria,1V52Z@1239|Firmicutes,24I1N@186801|Clostridia,3Y1IQ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00207	585394.RHOM_11645	1.73e-280	776.0	COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,247JT@186801|Clostridia	186801|Clostridia	H	coproporphyrinogen	hemZ	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
PNCOCPKN_00208	585394.RHOM_11650	3.32e-124	356.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia	186801|Clostridia	P	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
PNCOCPKN_00209	622312.ROSEINA2194_02168	0.0	1385.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
PNCOCPKN_00210	585394.RHOM_11660	6.42e-78	246.0	COG1670@1|root,COG1670@2|Bacteria,1V4FZ@1239|Firmicutes,24PF4@186801|Clostridia	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
PNCOCPKN_00211	1410650.JHWL01000003_gene2985	6.05e-48	186.0	28I6K@1|root,2Z89I@2|Bacteria,1UQ1M@1239|Firmicutes,24A0B@186801|Clostridia,4BWIK@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00212	585394.RHOM_04030	9.98e-195	542.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia	186801|Clostridia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
PNCOCPKN_00213	622312.ROSEINA2194_02248	1.78e-163	459.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
PNCOCPKN_00214	585394.RHOM_04020	1.65e-267	738.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
PNCOCPKN_00215	585394.RHOM_04015	4.08e-248	687.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
PNCOCPKN_00216	622312.ROSEINA2194_02245	5.38e-144	421.0	COG0457@1|root,COG0457@2|Bacteria,1V4J9@1239|Firmicutes,24HT2@186801|Clostridia	186801|Clostridia	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
PNCOCPKN_00217	1415775.U729_2133	4.11e-72	221.0	COG3153@1|root,COG3153@2|Bacteria,1UK0D@1239|Firmicutes,25FG9@186801|Clostridia,36V06@31979|Clostridiaceae	186801|Clostridia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_9
PNCOCPKN_00218	585394.RHOM_05980	1.66e-62	197.0	COG1595@1|root,COG1595@2|Bacteria,1V734@1239|Firmicutes,24MQB@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	sigV	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
PNCOCPKN_00219	585394.RHOM_05985	1.41e-112	335.0	COG5513@1|root,COG5513@2|Bacteria,1UIU3@1239|Firmicutes,25ERV@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3298)	rsiV	-	-	-	-	-	-	-	-	-	-	-	DUF3298,DUF4163
PNCOCPKN_00220	411902.CLOBOL_02174	2.65e-155	455.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,21Z7N@1506553|Lachnoclostridium	186801|Clostridia	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
PNCOCPKN_00221	742733.HMPREF9469_01435	1.6e-55	188.0	COG2755@1|root,COG2755@2|Bacteria,1V2MD@1239|Firmicutes,24FWG@186801|Clostridia,2201W@1506553|Lachnoclostridium	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
PNCOCPKN_00222	585394.RHOM_04340	6.77e-261	719.0	28HI8@1|root,2Z7TS@2|Bacteria,1TQTK@1239|Firmicutes,249WK@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4317
PNCOCPKN_00223	585394.RHOM_04335	1.02e-83	250.0	COG1329@1|root,COG1329@2|Bacteria,1VAA0@1239|Firmicutes,24P60@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
PNCOCPKN_00224	485916.Dtox_1961	1.43e-11	78.6	COG3210@1|root,COG3656@1|root,COG5492@1|root,COG3210@2|Bacteria,COG3656@2|Bacteria,COG5492@2|Bacteria,1VUQN@1239|Firmicutes,24CDA@186801|Clostridia,267DX@186807|Peptococcaceae	186801|Clostridia	N	PFAM Bacterial Ig-like domain (group 2)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,F5_F8_type_C,FIVAR,Flg_new,RHS_repeat,SH3_3,SLH,fn3
PNCOCPKN_00225	526218.Sterm_4199	5.52e-52	177.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
PNCOCPKN_00226	585394.RHOM_04285	1.87e-246	676.0	COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia	186801|Clostridia	G	Kinase, PfkB family	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
PNCOCPKN_00227	622312.ROSEINA2194_04459	2.09e-224	620.0	COG0524@1|root,COG0524@2|Bacteria,1TQ9Q@1239|Firmicutes,25B0T@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
PNCOCPKN_00228	585394.RHOM_04000	1.99e-132	389.0	COG2355@1|root,COG2355@2|Bacteria,1UA7M@1239|Firmicutes,24AE6@186801|Clostridia	186801|Clostridia	E	PFAM Peptidase M19, renal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
PNCOCPKN_00229	500632.CLONEX_03577	1.32e-32	135.0	COG0772@1|root,COG0772@2|Bacteria,1TRIP@1239|Firmicutes,25DEX@186801|Clostridia	186801|Clostridia	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
PNCOCPKN_00230	1235798.C817_04466	1.18e-43	145.0	COG1695@1|root,COG1695@2|Bacteria,1VAKA@1239|Firmicutes,24MVF@186801|Clostridia,27VT5@189330|Dorea	186801|Clostridia	K	Transcriptional regulator, PadR family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
PNCOCPKN_00231	592026.GCWU0000282_001791	9.7e-56	181.0	COG0685@1|root,COG0685@2|Bacteria,1TQFE@1239|Firmicutes,247ZK@186801|Clostridia	186801|Clostridia	E	5,10-methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
PNCOCPKN_00232	411463.EUBVEN_02650	1.17e-46	159.0	COG0583@1|root,COG0583@2|Bacteria,1TP3E@1239|Firmicutes,248HI@186801|Clostridia,25VUS@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PNCOCPKN_00233	1280679.ATVX01000004_gene452	1.25e-06	50.4	29155@1|root,2ZNSF@2|Bacteria,1W51U@1239|Firmicutes,257BM@186801|Clostridia,4C0H7@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00234	585394.RHOM_03995	0.0	1372.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	malP_1	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
PNCOCPKN_00235	622312.ROSEINA2194_02243	3.34e-167	472.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1TSRS@1239|Firmicutes,24BXX@186801|Clostridia	186801|Clostridia	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
PNCOCPKN_00236	585394.RHOM_03350	1.05e-214	615.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9
PNCOCPKN_00237	585394.RHOM_11515	3.34e-57	183.0	COG0671@1|root,COG0671@2|Bacteria,1VB2R@1239|Firmicutes,24MQ9@186801|Clostridia	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
PNCOCPKN_00238	585394.RHOM_11510	2.66e-66	205.0	COG0597@1|root,COG0597@2|Bacteria,1VFDG@1239|Firmicutes,24PUH@186801|Clostridia	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	-	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
PNCOCPKN_00239	1235790.C805_02487	2.01e-70	220.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1URF2@1239|Firmicutes,24BBP@186801|Clostridia,25ZEW@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
PNCOCPKN_00240	1235792.C808_04909	1.12e-53	171.0	COG1943@1|root,COG1943@2|Bacteria,1TSQ0@1239|Firmicutes,25CMS@186801|Clostridia,27U60@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
PNCOCPKN_00241	1410630.JNKP01000001_gene1787	1.63e-120	352.0	COG0726@1|root,COG0726@2|Bacteria,1U0B6@1239|Firmicutes,24895@186801|Clostridia,27M6G@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
PNCOCPKN_00242	585394.RHOM_04190	2.86e-64	201.0	COG4767@1|root,COG4767@2|Bacteria,1VAH6@1239|Firmicutes,24MQR@186801|Clostridia	186801|Clostridia	V	Glycopeptide antibiotics resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
PNCOCPKN_00243	585394.RHOM_04185	7.55e-143	405.0	COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
PNCOCPKN_00245	585394.RHOM_03840	3.86e-74	228.0	COG1595@1|root,COG1595@2|Bacteria,1V1JW@1239|Firmicutes,24FYN@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
PNCOCPKN_00246	658086.HMPREF0994_04050	2.67e-115	355.0	COG4826@1|root,COG4826@2|Bacteria,1UYKX@1239|Firmicutes,24B76@186801|Clostridia,27KFI@186928|unclassified Lachnospiraceae	186801|Clostridia	O	SERine  Proteinase INhibitors	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
PNCOCPKN_00247	622312.ROSEINA2194_02179	4.42e-32	118.0	2E5D8@1|root,33058@2|Bacteria,1VERG@1239|Firmicutes,24S0M@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1344
PNCOCPKN_00248	585394.RHOM_11845	7.01e-107	315.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,24JSE@186801|Clostridia	186801|Clostridia	G	xylanase chitin deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
PNCOCPKN_00249	397290.C810_02286	3.3e-124	371.0	COG1668@1|root,COG1668@2|Bacteria,1TQNC@1239|Firmicutes,2489Z@186801|Clostridia,27I77@186928|unclassified Lachnospiraceae	186801|Clostridia	CP	ABC-2 family transporter protein	natB	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,ABC2_membrane_3,Abi
PNCOCPKN_00250	1235790.C805_02060	1.35e-131	379.0	COG4555@1|root,COG4555@2|Bacteria,1UHYH@1239|Firmicutes,25E73@186801|Clostridia	186801|Clostridia	CP	ABC transporter	natA	-	3.6.3.7	ko:K09697	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.115	-	-	ABC_tran
PNCOCPKN_00251	585394.RHOM_11850	1.14e-19	93.2	COG1670@1|root,COG1670@2|Bacteria,1UHY0@1239|Firmicutes,25EFE@186801|Clostridia	186801|Clostridia	J	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
PNCOCPKN_00252	622312.ROSEINA2194_00544	1.84e-219	608.0	COG0463@1|root,COG0463@2|Bacteria,1TT6C@1239|Firmicutes,248F2@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	kfoC_2	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PNCOCPKN_00253	622312.ROSEINA2194_00543	8.1e-245	676.0	COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,249BR@186801|Clostridia	186801|Clostridia	M	UDP-galactopyranose mutase	glf	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,NAD_binding_8
PNCOCPKN_00254	622312.ROSEINA2194_00542	1.44e-186	528.0	COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,25E4K@186801|Clostridia	186801|Clostridia	L	A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4,SfsA
PNCOCPKN_00255	585394.RHOM_11880	4.76e-255	702.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia	186801|Clostridia	E	PFAM aminotransferase class I and II	yugH	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
PNCOCPKN_00256	1408312.JNJS01000004_gene2375	7.78e-170	476.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,3NGQJ@46205|Pseudobutyrivibrio	186801|Clostridia	I	Enoyl-CoA hydratase/isomerase	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
PNCOCPKN_00257	1280668.ATVT01000002_gene3088	2.03e-19	87.0	COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,24ACC@186801|Clostridia,4BYMQ@830|Butyrivibrio	186801|Clostridia	S	Sodium Bile acid symporter family	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
PNCOCPKN_00258	585394.RHOM_00265	1.59e-184	515.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UZ35@1239|Firmicutes,25BI3@186801|Clostridia	186801|Clostridia	K	COG2207 AraC-type DNA-binding domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
PNCOCPKN_00259	585394.RHOM_00260	1.09e-279	769.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
PNCOCPKN_00260	585394.RHOM_11890	1.88e-144	412.0	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,247SR@186801|Clostridia	186801|Clostridia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
PNCOCPKN_00261	585394.RHOM_11895	1.62e-295	808.0	COG0366@1|root,COG0366@2|Bacteria,1TQFJ@1239|Firmicutes,249Y3@186801|Clostridia	186801|Clostridia	G	Alpha amylase, catalytic domain protein	-	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Alpha-amylase_N
PNCOCPKN_00262	397290.C810_01003	1.51e-71	218.0	COG4506@1|root,COG4506@2|Bacteria,1V8CS@1239|Firmicutes,24JQR@186801|Clostridia,27N6U@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF1934)	ywiB	-	-	-	-	-	-	-	-	-	-	-	DUF1934
PNCOCPKN_00263	622312.ROSEINA2194_03400	1.9e-69	218.0	2AUKD@1|root,31K93@2|Bacteria,1V6PK@1239|Firmicutes,24J91@186801|Clostridia	186801|Clostridia	S	stage ii sporulation protein r	spoIIR	-	-	ko:K06387	-	-	-	-	ko00000	-	-	-	Spore_II_R
PNCOCPKN_00264	585394.RHOM_11780	3.83e-213	620.0	COG0814@1|root,COG0814@2|Bacteria,1V9NE@1239|Firmicutes,25DGZ@186801|Clostridia	186801|Clostridia	E	Spore germination protein	-	-	-	-	-	-	-	-	-	-	-	-	Spore_permease
PNCOCPKN_00265	585394.RHOM_11785	3.68e-293	807.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,248Q8@186801|Clostridia	186801|Clostridia	EG	GerA spore germination protein	gerA	-	-	ko:K06310	-	-	-	-	ko00000	-	-	-	GerA
PNCOCPKN_00266	622312.ROSEINA2194_03403	7.82e-129	369.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24C0U@186801|Clostridia	186801|Clostridia	K	domain protein	GntR	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
PNCOCPKN_00267	622312.ROSEINA2194_03404	6.15e-170	479.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia	186801|Clostridia	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
PNCOCPKN_00268	585394.RHOM_11800	1.91e-89	268.0	2BYUV@1|root,307Y4@2|Bacteria,1V64G@1239|Firmicutes,24K9A@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00269	585394.RHOM_11810	2.93e-299	817.0	COG1167@1|root,COG1167@2|Bacteria,1TPMY@1239|Firmicutes,24986@186801|Clostridia	186801|Clostridia	EK	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_MocR
PNCOCPKN_00270	585394.RHOM_11815	7.72e-281	772.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia	186801|Clostridia	L	ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
PNCOCPKN_00271	1410628.JNKS01000072_gene1060	9.09e-159	459.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,27IMU@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iHN637.CLJU_RS20420	Mur_ligase_C,Mur_ligase_M
PNCOCPKN_00272	1408321.JNJD01000008_gene2040	2.03e-184	528.0	COG0603@1|root,COG0603@2|Bacteria,1V0EU@1239|Firmicutes,24BK5@186801|Clostridia,27KYX@186928|unclassified Lachnospiraceae	186801|Clostridia	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00273	585394.RHOM_11905	2.8e-203	582.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia	186801|Clostridia	O	PDZ DHR GLGF domain protein	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
PNCOCPKN_00274	585394.RHOM_11910	4.69e-175	505.0	2DSN8@1|root,33GRU@2|Bacteria,1VPDR@1239|Firmicutes,24PGY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00275	585394.RHOM_11920	1.03e-159	456.0	COG1216@1|root,COG1216@2|Bacteria,1TSXW@1239|Firmicutes,2499G@186801|Clostridia	186801|Clostridia	S	Glycosyltransferase, group 2 family protein	-	-	-	ko:K12992	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
PNCOCPKN_00276	585394.RHOM_11925	1.27e-187	531.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia	186801|Clostridia	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
PNCOCPKN_00277	585394.RHOM_11930	1.51e-300	824.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia	186801|Clostridia	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	-	-	2.7.8.6	ko:K00996	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Bac_transf,CoA_binding_3
PNCOCPKN_00278	622312.ROSEINA2194_02504	3.1e-155	444.0	COG1216@1|root,COG1216@2|Bacteria,1TSTE@1239|Firmicutes,249WH@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
PNCOCPKN_00279	585394.RHOM_11940	0.0	915.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
PNCOCPKN_00280	585394.RHOM_11945	7.2e-33	114.0	2E96G@1|root,333F2@2|Bacteria,1VHVR@1239|Firmicutes,24SE5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00281	585394.RHOM_11950	0.0	1137.0	COG0463@1|root,COG1216@1|root,COG0463@2|Bacteria,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
PNCOCPKN_00282	483218.BACPEC_02375	5.61e-208	583.0	COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,25B1W@186801|Clostridia,2682F@186813|unclassified Clostridiales	186801|Clostridia	M	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
PNCOCPKN_00283	585394.RHOM_11955	5.19e-158	450.0	COG2333@1|root,COG2333@2|Bacteria,1UEY5@1239|Firmicutes,24E8K@186801|Clostridia	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
PNCOCPKN_00285	585394.RHOM_11965	5.86e-61	189.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
PNCOCPKN_00286	585394.RHOM_12000	7.03e-258	714.0	COG0836@1|root,COG1917@1|root,COG0836@2|Bacteria,COG1917@2|Bacteria,1TPC9@1239|Firmicutes,24908@186801|Clostridia	186801|Clostridia	M	PFAM Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
PNCOCPKN_00287	585394.RHOM_12005	4.97e-221	610.0	COG0451@1|root,COG0451@2|Bacteria,1TQV2@1239|Firmicutes,249R2@186801|Clostridia	186801|Clostridia	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
PNCOCPKN_00288	585394.RHOM_12010	1.1e-235	649.0	COG1089@1|root,COG1089@2|Bacteria,1TQ9T@1239|Firmicutes,24863@186801|Clostridia	186801|Clostridia	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
PNCOCPKN_00289	585394.RHOM_12015	4.92e-143	411.0	COG2207@1|root,COG2207@2|Bacteria,1V1FV@1239|Firmicutes,24887@186801|Clostridia	186801|Clostridia	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
PNCOCPKN_00290	585394.RHOM_12025	6.17e-114	341.0	COG3594@1|root,COG3594@2|Bacteria,1VJ6T@1239|Firmicutes,24UK1@186801|Clostridia	186801|Clostridia	G	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
PNCOCPKN_00291	483218.BACPEC_02363	1.54e-293	819.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,247YA@186801|Clostridia,268P3@186813|unclassified Clostridiales	186801|Clostridia	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
PNCOCPKN_00292	585394.RHOM_12030	5.76e-120	348.0	COG1922@1|root,COG1922@2|Bacteria,1UIHR@1239|Firmicutes,25BDH@186801|Clostridia	186801|Clostridia	M	Belongs to the glycosyltransferase 26 family	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	CoA_binding_3,Glyco_tran_WecB
PNCOCPKN_00293	585394.RHOM_12035	8.32e-92	280.0	2DMX9@1|root,32U7V@2|Bacteria,1W0SU@1239|Firmicutes,24QVG@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00294	585394.RHOM_12040	2.44e-252	711.0	COG1132@1|root,COG1132@2|Bacteria,1TQAN@1239|Firmicutes,24BEK@186801|Clostridia	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
PNCOCPKN_00295	585394.RHOM_12075	1.46e-107	320.0	arCOG09486@1|root,2ZC3Y@2|Bacteria,1VABR@1239|Firmicutes,24F51@186801|Clostridia	186801|Clostridia	S	Glycosyl transferase family 11	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_11
PNCOCPKN_00296	1123307.KB904364_gene1166	4.44e-76	255.0	COG1807@1|root,COG1807@2|Bacteria,1V11Z@1239|Firmicutes,4ISNZ@91061|Bacilli	91061|Bacilli	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
PNCOCPKN_00298	632245.CLP_3145	5.77e-97	293.0	COG0382@1|root,COG0382@2|Bacteria,1TRTB@1239|Firmicutes,24AQ0@186801|Clostridia,36E6F@31979|Clostridiaceae	186801|Clostridia	H	PFAM UbiA prenyltransferase	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
PNCOCPKN_00299	585394.RHOM_11975	1.16e-129	395.0	28PI9@1|root,2ZC8C@2|Bacteria,1V6ZI@1239|Firmicutes,24M4V@186801|Clostridia	186801|Clostridia	S	Glucosyl transferase GtrII	-	-	-	-	-	-	-	-	-	-	-	-	Glucos_trans_II
PNCOCPKN_00300	1235793.C809_03429	8.24e-85	265.0	2DBCR@1|root,2Z8FA@2|Bacteria,1V8ZT@1239|Firmicutes,24KB5@186801|Clostridia,27MF2@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00301	489825.LYNGBM3L_09380	7.06e-16	84.7	2C7E6@1|root,32JF5@2|Bacteria,1G9FH@1117|Cyanobacteria,1HG1Y@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00302	585394.RHOM_12020	6.16e-59	201.0	COG3274@1|root,COG3274@2|Bacteria,1V90B@1239|Firmicutes,24IC7@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
PNCOCPKN_00303	877424.ATWC01000003_gene1798	1.35e-26	116.0	COG3274@1|root,COG3274@2|Bacteria,1VFZD@1239|Firmicutes,25D9I@186801|Clostridia	186801|Clostridia	S	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
PNCOCPKN_00304	626369.HMPREF0446_00571	1.08e-27	118.0	COG0438@1|root,COG0438@2|Bacteria,1UZFG@1239|Firmicutes,4ISTK@91061|Bacilli	91061|Bacilli	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00307	585394.RHOM_12090	4.82e-204	571.0	COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,24EHG@186801|Clostridia	186801|Clostridia	D	Protein of unknown function (DUF3048) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
PNCOCPKN_00308	397288.C806_01854	7.75e-85	289.0	COG5279@1|root,COG5279@2|Bacteria,1VEK2@1239|Firmicutes,24SMT@186801|Clostridia,27NZA@186928|unclassified Lachnospiraceae	186801|Clostridia	D	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,Transglut_core
PNCOCPKN_00309	585394.RHOM_12095	1.88e-189	530.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,248Q5@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
PNCOCPKN_00310	1410658.JHWI01000034_gene1952	8.88e-178	501.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,3VP1J@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PNCOCPKN_00311	515620.EUBELI_00113	1.13e-63	199.0	COG2246@1|root,COG2246@2|Bacteria,1VESW@1239|Firmicutes,24QSN@186801|Clostridia,25XGV@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
PNCOCPKN_00312	742735.HMPREF9467_05195	4.82e-294	814.0	COG4974@1|root,COG4974@2|Bacteria,1TQST@1239|Firmicutes,247YT@186801|Clostridia	186801|Clostridia	L	PFAM transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
PNCOCPKN_00313	1235790.C805_02393	1.64e-41	141.0	28IAH@1|root,333F9@2|Bacteria,1VHRU@1239|Firmicutes,24SK6@186801|Clostridia,25XZW@186806|Eubacteriaceae	186801|Clostridia	S	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
PNCOCPKN_00314	1449050.JNLE01000003_gene119	0.0	1177.0	COG4096@1|root,COG4096@2|Bacteria,1UI7V@1239|Firmicutes,25ED3@186801|Clostridia,36UKU@31979|Clostridiaceae	186801|Clostridia	L	Type III restriction protein res subunit	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF4145,EcoEI_R_C,HSDR_N,HSDR_N_2,Helicase_C,ResIII
PNCOCPKN_00315	1280682.AUKA01000001_gene1480	1.01e-292	800.0	COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,248JG@186801|Clostridia,4BX89@830|Butyrivibrio	186801|Clostridia	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,HhH-GPD,Transposase_20
PNCOCPKN_00316	1235802.C823_04039	6.79e-55	180.0	2E72M@1|root,331M8@2|Bacteria,1W0VG@1239|Firmicutes,24PYZ@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2971
PNCOCPKN_00317	1449050.JNLE01000003_gene118	0.0	887.0	COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,247RY@186801|Clostridia,36DVJ@31979|Clostridiaceae	186801|Clostridia	V	type I restriction-modification system	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,Methylase_S,N6_Mtase
PNCOCPKN_00318	428127.EUBDOL_00356	5.36e-116	358.0	COG0732@1|root,COG0732@2|Bacteria,1TT1D@1239|Firmicutes	1239|Firmicutes	V	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
PNCOCPKN_00319	523845.AQXV01000040_gene1689	5.5e-162	474.0	arCOG12080@1|root,arCOG12080@2157|Archaea,2Y30S@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00320	1280698.AUJS01000017_gene1812	3.44e-186	516.0	2CET8@1|root,2Z7N2@2|Bacteria,1TT9T@1239|Firmicutes,24AN8@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00321	1280698.AUJS01000017_gene1813	9.99e-94	279.0	COG3613@1|root,COG3613@2|Bacteria,1VB16@1239|Firmicutes,25HCA@186801|Clostridia	186801|Clostridia	F	Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5- phosphate and a purine or pyrimidine base	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00322	1280679.ATVX01000013_gene2616	2.14e-09	60.5	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,249Q3@186801|Clostridia,4BX8N@830|Butyrivibrio	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PNCOCPKN_00323	585394.RHOM_05925	4.38e-233	655.0	COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,248X1@186801|Clostridia	186801|Clostridia	S	associated with various cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
PNCOCPKN_00324	515620.EUBELI_00163	9.86e-280	773.0	COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,247NY@186801|Clostridia,25URI@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C,QRPTase_N
PNCOCPKN_00325	658086.HMPREF0994_07307	2.44e-229	645.0	28JJB@1|root,2Z9CE@2|Bacteria,1U6BP@1239|Firmicutes,24B0T@186801|Clostridia,27UAP@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00326	1226325.HMPREF1548_05144	4.54e-85	261.0	2A92C@1|root,30Y6D@2|Bacteria,1V59Y@1239|Firmicutes,25HP5@186801|Clostridia,36I7M@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF4194)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4194
PNCOCPKN_00327	1226325.HMPREF1548_05145	0.0	1422.0	COG4913@1|root,COG4913@2|Bacteria,1TPVZ@1239|Firmicutes,2491E@186801|Clostridia,36EUY@31979|Clostridiaceae	186801|Clostridia	S	DNA replication and repair protein RecF	-	-	-	-	-	-	-	-	-	-	-	-	AAA_29,SMC_hinge,SbcCD_C
PNCOCPKN_00328	585394.RHOM_05930	1.39e-307	850.0	COG3044@1|root,COG3044@2|Bacteria,1TPJ9@1239|Firmicutes,248G5@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_ATPase
PNCOCPKN_00329	428125.CLOLEP_01728	0.0	1314.0	COG0178@1|root,COG0178@2|Bacteria,1TP0A@1239|Firmicutes,24B3G@186801|Clostridia,3WN9G@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
PNCOCPKN_00330	515620.EUBELI_00659	3.48e-239	669.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,25VPU@186806|Eubacteriaceae	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
PNCOCPKN_00331	350688.Clos_2061	1.96e-25	112.0	28NDR@1|root,2ZBGG@2|Bacteria,1TSYU@1239|Firmicutes,24E7Y@186801|Clostridia,36PP2@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00332	1469948.JPNB01000001_gene2285	0.0	1104.0	COG0480@1|root,COG3688@1|root,COG0480@2|Bacteria,COG3688@2|Bacteria,1TPQH@1239|Firmicutes,247X4@186801|Clostridia,36DHY@31979|Clostridiaceae	186801|Clostridia	J	elongation factor G	tetP	-	-	-	-	-	-	-	-	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,NYN_YacP
PNCOCPKN_00333	585394.RHOM_05940	4.24e-24	93.6	2EHJU@1|root,33BBQ@2|Bacteria,1VN8N@1239|Firmicutes,24VAU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00335	1226325.HMPREF1548_03838	6.22e-06	45.1	2BEGM@1|root,3287Y@2|Bacteria,1UU58@1239|Firmicutes,255IQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00336	1226325.HMPREF1548_02366	3.31e-123	355.0	COG2964@1|root,COG2964@2|Bacteria,1V33R@1239|Firmicutes,25CHI@186801|Clostridia,36WW5@31979|Clostridiaceae	186801|Clostridia	S	HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_22,PAS_6
PNCOCPKN_00337	658086.HMPREF0994_00211	4.79e-63	195.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,27N9W@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
PNCOCPKN_00338	658086.HMPREF0994_00210	0.0	897.0	COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,248WN@186801|Clostridia,27TF9@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Na+/H+ antiporter family	nhaC	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
PNCOCPKN_00339	1226325.HMPREF1548_02362	2.37e-231	642.0	COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,248AY@186801|Clostridia,36DKQ@31979|Clostridiaceae	186801|Clostridia	E	PFAM Aminotransferase class I and II	-	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
PNCOCPKN_00340	1235793.C809_02152	3.22e-207	580.0	COG4804@1|root,COG4804@2|Bacteria,1TP7Q@1239|Firmicutes,24A19@186801|Clostridia,27TF6@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF1016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
PNCOCPKN_00341	585394.RHOM_05960	3.56e-222	627.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1TPGQ@1239|Firmicutes,247N0@186801|Clostridia	186801|Clostridia	J	NOL1 NOP2 sun family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
PNCOCPKN_00342	397287.C807_02411	7.26e-84	253.0	COG4720@1|root,COG4720@2|Bacteria,1V5I7@1239|Firmicutes,25CJU@186801|Clostridia,27U5H@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Pfam:DUF3816	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
PNCOCPKN_00343	556261.HMPREF0240_03527	0.0	919.0	COG4637@1|root,COG4637@2|Bacteria,1UZCB@1239|Firmicutes,248WE@186801|Clostridia,36PCY@31979|Clostridiaceae	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
PNCOCPKN_00344	397291.C804_04805	1.38e-210	595.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,27IAA@186928|unclassified Lachnospiraceae	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PNCOCPKN_00345	622312.ROSEINA2194_04371	2.92e-172	485.0	COG1284@1|root,COG1284@2|Bacteria,1TYTP@1239|Firmicutes,25CBP@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
PNCOCPKN_00347	596153.Alide_1289	2.12e-05	49.3	COG0834@1|root,COG2199@1|root,COG0834@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VMMZ@28216|Betaproteobacteria,4ACWB@80864|Comamonadaceae	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_3,PAS_4,Response_reg,SBP_bac_3,dCache_1
PNCOCPKN_00348	518637.EUBIFOR_01475	8.05e-19	84.0	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,3VQ8R@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Oxidoreductase, aldo keto reductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
PNCOCPKN_00349	1235793.C809_02425	9.25e-45	147.0	2C5R4@1|root,31VPY@2|Bacteria,1V8EP@1239|Firmicutes,24JPJ@186801|Clostridia,27MNA@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
PNCOCPKN_00350	511680.BUTYVIB_01780	2.56e-110	324.0	COG5464@1|root,COG5464@2|Bacteria,1TS6U@1239|Firmicutes,24A2X@186801|Clostridia,4BZZ4@830|Butyrivibrio	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00351	622312.ROSEINA2194_01195	2.48e-94	281.0	COG5464@1|root,COG5464@2|Bacteria,1UA0N@1239|Firmicutes,247X9@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
PNCOCPKN_00352	397291.C804_05879	1.68e-63	204.0	28JS8@1|root,2Z9HS@2|Bacteria,1UY4F@1239|Firmicutes,248MI@186801|Clostridia,27IR8@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00353	397291.C804_05881	8.02e-18	77.4	2DP8A@1|root,330ZM@2|Bacteria,1VI6E@1239|Firmicutes,24QGV@186801|Clostridia,27NXF@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TnpW
PNCOCPKN_00354	1235800.C819_00815	5.74e-259	731.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,27J4S@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Domain of unknown function (DUF4368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
PNCOCPKN_00356	585394.RHOM_16355	1.24e-97	292.0	COG3279@1|root,COG3279@2|Bacteria,1V217@1239|Firmicutes,24GJ1@186801|Clostridia	186801|Clostridia	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
PNCOCPKN_00357	585394.RHOM_16350	6.11e-202	571.0	COG3290@1|root,COG3290@2|Bacteria,1V225@1239|Firmicutes,24DB7@186801|Clostridia	186801|Clostridia	T	signal transduction protein with a C-terminal ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
PNCOCPKN_00358	483218.BACPEC_00110	2.3e-49	168.0	28KQP@1|root,314YH@2|Bacteria,1V8JK@1239|Firmicutes,24EPX@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4885
PNCOCPKN_00359	483218.BACPEC_01770	1.14e-155	439.0	2AE4I@1|root,313XT@2|Bacteria,1V86Q@1239|Firmicutes,24KFS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00360	397291.C804_05921	1.9e-23	99.4	2DVXT@1|root,33XMK@2|Bacteria,1VWBJ@1239|Firmicutes,251C0@186801|Clostridia,27M7C@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00361	515620.EUBELI_20007	4.07e-100	296.0	29EZB@1|root,301X4@2|Bacteria,1V54H@1239|Firmicutes,24I4P@186801|Clostridia,25YN8@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00362	1235800.C819_01439	3.51e-96	296.0	2EVV1@1|root,33P8S@2|Bacteria,1VNF6@1239|Firmicutes,24VSM@186801|Clostridia,27N91@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00363	511680.BUTYVIB_02361	2e-103	305.0	290UV@1|root,2ZNGV@2|Bacteria,1V2HB@1239|Firmicutes,24GF7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00364	483218.BACPEC_01765	1.32e-164	461.0	COG3279@1|root,COG3279@2|Bacteria,1TSDB@1239|Firmicutes,24MQ4@186801|Clostridia,269MD@186813|unclassified Clostridiales	186801|Clostridia	KT	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
PNCOCPKN_00365	515620.EUBELI_00191	0.0	869.0	COG3290@1|root,COG3290@2|Bacteria,1TRW9@1239|Firmicutes,24D9R@186801|Clostridia,25W5A@186806|Eubacteriaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,SPOB_a
PNCOCPKN_00366	515620.EUBELI_00193	4.21e-153	435.0	COG4223@1|root,COG4223@2|Bacteria,1V01S@1239|Firmicutes,249JR@186801|Clostridia,25WJS@186806|Eubacteriaceae	186801|Clostridia	S	FlxA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	FlxA
PNCOCPKN_00367	483218.BACPEC_01768	1.82e-164	462.0	COG1345@1|root,COG1345@2|Bacteria,1V1XI@1239|Firmicutes,24GW8@186801|Clostridia	186801|Clostridia	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00368	483218.BACPEC_01769	1.03e-101	298.0	2B7HH@1|root,320MM@2|Bacteria,1V7BY@1239|Firmicutes,24KSD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00369	483218.BACPEC_01770	4.26e-171	478.0	2AE4I@1|root,313XT@2|Bacteria,1V86Q@1239|Firmicutes,24KFS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00370	483218.BACPEC_01771	3.72e-29	108.0	2DWFF@1|root,32V1I@2|Bacteria,1VDEW@1239|Firmicutes,24PX0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00371	483218.BACPEC_01771	1.66e-92	273.0	2DWFF@1|root,32V1I@2|Bacteria,1VDEW@1239|Firmicutes,24PX0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00372	483218.BACPEC_02677	1.76e-50	167.0	28S3E@1|root,335CC@2|Bacteria,1VHAF@1239|Firmicutes,24TDZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00373	1256908.HMPREF0373_00590	1.81e-133	380.0	2DD90@1|root,2ZH3Q@2|Bacteria,1V1HB@1239|Firmicutes,24GNM@186801|Clostridia,25YGQ@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function, E. rectale Gene description (DUF3879)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3879
PNCOCPKN_00374	689781.AUJX01000061_gene567	6.86e-260	720.0	COG1373@1|root,COG1373@2|Bacteria,1TQ8Z@1239|Firmicutes,24BKQ@186801|Clostridia,2PRAW@265975|Oribacterium	186801|Clostridia	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
PNCOCPKN_00375	180332.JTGN01000001_gene4817	1.21e-99	300.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1V2EN@1239|Firmicutes,24GG9@186801|Clostridia	186801|Clostridia	K	PFAM helix-turn-helix- domain containing protein AraC type	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
PNCOCPKN_00376	1469948.JPNB01000001_gene965	3.7e-308	853.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,36DEY@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PNCOCPKN_00377	1469948.JPNB01000001_gene966	0.0	889.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,36E82@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PNCOCPKN_00378	1195236.CTER_3491	2.28e-204	584.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V4UB@1239|Firmicutes,24BJM@186801|Clostridia,3WRKI@541000|Ruminococcaceae	186801|Clostridia	K	PFAM response regulator receiver	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
PNCOCPKN_00379	180332.JTGN01000016_gene1038	0.0	991.0	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,2492T@186801|Clostridia	186801|Clostridia	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
PNCOCPKN_00380	357809.Cphy_0218	0.0	1189.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,21YQ6@1506553|Lachnoclostridium	186801|Clostridia	G	Galactose mutarotase-like	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,Gal_mutarotas_2,Glyco_hydro_31
PNCOCPKN_00381	642492.Clole_1639	2.72e-304	855.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia	186801|Clostridia	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
PNCOCPKN_00382	585394.RHOM_06360	2.38e-269	771.0	COG2199@1|root,COG2200@1|root,COG2200@2|Bacteria,COG3706@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,Response_reg
PNCOCPKN_00383	585394.RHOM_06365	1.22e-36	127.0	COG2198@1|root,COG2198@2|Bacteria,1VGD4@1239|Firmicutes,25CZI@186801|Clostridia	186801|Clostridia	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
PNCOCPKN_00384	2325.TKV_c09470	1.65e-25	106.0	COG2091@1|root,COG2091@2|Bacteria,1VEYZ@1239|Firmicutes,24RQ3@186801|Clostridia,42GYT@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the P-Pant transferase superfamily	sfp	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
PNCOCPKN_00385	585394.RHOM_06375	5.92e-102	296.0	COG0782@1|root,COG0782@2|Bacteria,1V1G3@1239|Firmicutes,24FRJ@186801|Clostridia	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA_2	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
PNCOCPKN_00386	585394.RHOM_06380	5.43e-179	501.0	COG0685@1|root,COG0685@2|Bacteria,1TQFE@1239|Firmicutes,247ZK@186801|Clostridia	186801|Clostridia	E	5,10-methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
PNCOCPKN_00387	622312.ROSEINA2194_02781	1.74e-56	181.0	2EF5Q@1|root,338YV@2|Bacteria,1VJS5@1239|Firmicutes,24RWV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00388	585394.RHOM_13440	1.31e-160	455.0	28KEH@1|root,2ZA0R@2|Bacteria,1V76J@1239|Firmicutes,24JHU@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4300)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4300
PNCOCPKN_00389	411461.DORFOR_03149	1.7e-101	306.0	COG0526@1|root,COG0526@2|Bacteria,1UY9A@1239|Firmicutes,24C03@186801|Clostridia,27WII@189330|Dorea	186801|Clostridia	M	COG COG0526 Thiol-disulfide isomerase and THIoredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
PNCOCPKN_00390	1256908.HMPREF0373_00304	4.17e-188	525.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,25V01@186806|Eubacteriaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
PNCOCPKN_00391	411474.COPEUT_01943	8.25e-138	392.0	COG0745@1|root,COG0745@2|Bacteria,1TSRR@1239|Firmicutes,24AG3@186801|Clostridia	186801|Clostridia	T	Psort location Cytoplasmic, score	cutR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PNCOCPKN_00392	411489.CLOL250_00372	2.31e-231	642.0	COG0642@1|root,COG2205@2|Bacteria,1UHQC@1239|Firmicutes,2496X@186801|Clostridia,36HCI@31979|Clostridiaceae	186801|Clostridia	T	Signal transduction histidine kinase	arlS	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
PNCOCPKN_00393	397288.C806_04417	2.59e-08	57.0	COG1132@1|root,COG1132@2|Bacteria,1US0C@1239|Firmicutes,24EZJ@186801|Clostridia,27M01@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
PNCOCPKN_00394	622312.ROSEINA2194_00222	1.17e-175	491.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,2483H@186801|Clostridia	186801|Clostridia	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
PNCOCPKN_00395	585394.RHOM_13420	2.78e-246	681.0	COG1457@1|root,COG1457@2|Bacteria,1TTBN@1239|Firmicutes,248EP@186801|Clostridia	186801|Clostridia	F	PFAM Permease for cytosine purines, uracil, thiamine, allantoin	cytX	-	-	-	-	-	-	-	-	-	-	-	Transp_cyt_pur
PNCOCPKN_00396	585394.RHOM_13415	1.3e-111	321.0	COG4732@1|root,COG4732@2|Bacteria,1V6HH@1239|Firmicutes,24JF7@186801|Clostridia	186801|Clostridia	S	ThiW protein	thiW	-	-	-	-	-	-	-	-	-	-	-	ThiW
PNCOCPKN_00397	471875.RUMLAC_00916	6.1e-101	293.0	COG0454@1|root,COG0456@2|Bacteria,1V77V@1239|Firmicutes,24HI8@186801|Clostridia,3WIP1@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
PNCOCPKN_00398	742735.HMPREF9467_04133	4.72e-08	53.9	COG3385@1|root,COG3385@2|Bacteria,1UTR4@1239|Firmicutes,24CFF@186801|Clostridia,221YR@1506553|Lachnoclostridium	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
PNCOCPKN_00400	97138.C820_01532	5.45e-54	176.0	COG1476@1|root,COG1476@2|Bacteria,1UHWD@1239|Firmicutes,25EEZ@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PNCOCPKN_00401	1280698.AUJS01000133_gene2149	4.42e-182	510.0	COG2801@1|root,COG2801@2|Bacteria,1TRV8@1239|Firmicutes,24BSY@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
PNCOCPKN_00402	1280698.AUJS01000133_gene2150	1.59e-62	192.0	COG2963@1|root,COG2963@2|Bacteria,1V6RE@1239|Firmicutes,24P5I@186801|Clostridia	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
PNCOCPKN_00403	585394.RHOM_06395	1.15e-163	478.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,247ZH@186801|Clostridia	186801|Clostridia	P	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
PNCOCPKN_00404	585394.RHOM_06400	1.49e-147	419.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia	186801|Clostridia	S	(AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
PNCOCPKN_00405	585394.RHOM_06405	6.83e-98	288.0	COG1309@1|root,COG1309@2|Bacteria,1V7SY@1239|Firmicutes,24JI6@186801|Clostridia	186801|Clostridia	K	transcriptional regulator TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
PNCOCPKN_00406	1235800.C819_03666	0.0	1089.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,249UZ@186801|Clostridia,27TNA@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolases family 2, TIM barrel domain	lacZ	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
PNCOCPKN_00407	585394.RHOM_06415	5.63e-290	799.0	2BZA3@1|root,2Z7YV@2|Bacteria,1TSER@1239|Firmicutes,24AF5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00408	585394.RHOM_06420	2.62e-259	719.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,247VA@186801|Clostridia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	lacS	-	-	ko:K03292,ko:K11104,ko:K16209	-	-	-	-	ko00000,ko02000	2.A.2,2.A.2.1,2.A.2.2	-	-	MFS_2
PNCOCPKN_00409	622312.ROSEINA2194_01205	0.0	1191.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia	186801|Clostridia	G	alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
PNCOCPKN_00410	483218.BACPEC_02162	4.41e-07	52.8	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PNCOCPKN_00411	536233.CLO_3167	3e-22	99.0	COG1763@1|root,COG1763@2|Bacteria,1VAIZ@1239|Firmicutes,24N6J@186801|Clostridia,36UPV@31979|Clostridiaceae	186801|Clostridia	H	selenium-dependent hydroxylase accessory protein YqeC	yqeC	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00412	585394.RHOM_06540	1.15e-267	742.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia	186801|Clostridia	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
PNCOCPKN_00413	585394.RHOM_06545	4.86e-114	329.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,24FR0@186801|Clostridia	186801|Clostridia	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
PNCOCPKN_00414	585394.RHOM_06550	3.64e-126	365.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,249ZY@186801|Clostridia	186801|Clostridia	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
PNCOCPKN_00415	585394.RHOM_06555	2.92e-55	183.0	COG0135@1|root,COG0135@2|Bacteria	2|Bacteria	E	phosphoribosylanthranilate isomerase activity	trpF	GO:0000162,GO:0003674,GO:0003824,GO:0004425,GO:0004640,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.48,4.2.1.160,4.2.1.20,5.3.1.24	ko:K01696,ko:K01817,ko:K13498,ko:K22100	ko00260,ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map00790,map01100,map01110,map01130,map01230	M00023,M00840	R00674,R02340,R02722,R03508,R03509,R11072	RC00209,RC00210,RC00700,RC00701,RC00944,RC00945,RC02868,RC03343	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.trpF,iPC815.YPO2205,iSBO_1134.SBO_1804,iSDY_1059.SDY_1330	IGPS,PRAI
PNCOCPKN_00416	585394.RHOM_06560	3.64e-257	709.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,24881@186801|Clostridia	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20,5.3.1.24	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03509	RC00209,RC00210,RC00700,RC00701,RC00945,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,PRAI
PNCOCPKN_00417	585394.RHOM_06565	2.18e-137	394.0	COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,248M2@186801|Clostridia	186801|Clostridia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
PNCOCPKN_00418	585394.RHOM_06570	4.55e-178	503.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia	186801|Clostridia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
PNCOCPKN_00419	622312.ROSEINA2194_01198	3.02e-207	578.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,248TR@186801|Clostridia	186801|Clostridia	E	Beta-eliminating lyase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
PNCOCPKN_00420	585394.RHOM_06580	6.4e-219	607.0	COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,248F3@186801|Clostridia	186801|Clostridia	EJ	L-asparaginase	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
PNCOCPKN_00421	585394.RHOM_06585	7.78e-79	241.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HPU@186801|Clostridia	186801|Clostridia	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
PNCOCPKN_00423	622312.ROSEINA2194_01760	1.03e-257	711.0	COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,247R4@186801|Clostridia	186801|Clostridia	P	Chloride transporter, ClC family	clcA	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
PNCOCPKN_00424	622312.ROSEINA2194_01762	1.8e-278	769.0	COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia	186801|Clostridia	G	ABC transporter, solute-binding protein	amyE	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8,TAT_signal
PNCOCPKN_00425	622312.ROSEINA2194_01763	3.89e-184	514.0	COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,24ADV@186801|Clostridia	186801|Clostridia	P	Abc transporter, permease protein	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
PNCOCPKN_00426	585394.RHOM_06625	3.01e-178	499.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia	186801|Clostridia	P	sugar transport system permease	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
PNCOCPKN_00427	585394.RHOM_06630	1.68e-192	540.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
PNCOCPKN_00428	622312.ROSEINA2194_01766	6.25e-314	860.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia	186801|Clostridia	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
PNCOCPKN_00429	585394.RHOM_06640	7.59e-136	395.0	COG1597@1|root,COG1597@2|Bacteria,1V7DZ@1239|Firmicutes,25CN5@186801|Clostridia	186801|Clostridia	I	Diacylglycerol kinase catalytic domain	ytlR	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
PNCOCPKN_00430	585394.RHOM_06645	1.17e-267	744.0	COG0699@1|root,COG0699@2|Bacteria,1TPPG@1239|Firmicutes,24829@186801|Clostridia	186801|Clostridia	S	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	spoIVA	GO:0000003,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0008144,GO:0008150,GO:0009653,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019954,GO:0030154,GO:0030312,GO:0030435,GO:0030436,GO:0030554,GO:0031160,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0034301,GO:0035639,GO:0036094,GO:0042601,GO:0042763,GO:0043167,GO:0043168,GO:0043934,GO:0043936,GO:0044464,GO:0048646,GO:0048856,GO:0048869,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K06398	-	-	-	-	ko00000	-	-	-	Spore_IV_A
PNCOCPKN_00431	585394.RHOM_06665	1.79e-101	300.0	COG2364@1|root,COG2364@2|Bacteria,1V7N6@1239|Firmicutes,25CWQ@186801|Clostridia	186801|Clostridia	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00432	585394.RHOM_06660	4.36e-59	191.0	2DY6R@1|root,32V4T@2|Bacteria,1VDMI@1239|Firmicutes,24D1Z@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00433	585394.RHOM_06670	5.9e-172	483.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,247KQ@186801|Clostridia	186801|Clostridia	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
PNCOCPKN_00434	585394.RHOM_06675	1.68e-293	803.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia	186801|Clostridia	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31,3.5.4.40	ko:K12960,ko:K20810	ko00130,ko00270,ko01100,ko01110,map00130,map00270,map01100,map01110	-	R09660,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
PNCOCPKN_00435	622312.ROSEINA2194_03293	5.85e-141	402.0	COG2220@1|root,COG2220@2|Bacteria,1V3HY@1239|Firmicutes,24HK9@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	folD4	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
PNCOCPKN_00437	622312.ROSEINA2194_03291	0.0	1544.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
PNCOCPKN_00438	585394.RHOM_06695	7.69e-95	298.0	COG0840@1|root,COG0840@2|Bacteria	2|Bacteria	NT	transmembrane signaling receptor activity	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1,sCache_2
PNCOCPKN_00439	180332.JTGN01000001_gene5293	8.12e-05	52.8	COG5492@1|root,COG5492@2|Bacteria,1TQGW@1239|Firmicutes,25END@186801|Clostridia	186801|Clostridia	N	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430
PNCOCPKN_00440	585394.RHOM_06700	3.98e-29	104.0	COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,24QP9@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
PNCOCPKN_00442	585394.RHOM_06705	5.14e-116	336.0	COG1139@1|root,COG1139@2|Bacteria,1TP90@1239|Firmicutes,249B6@186801|Clostridia	186801|Clostridia	C	PFAM Uncharacterised ACR, YkgG family COG1556	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom
PNCOCPKN_00443	585394.RHOM_14145	2.36e-171	481.0	COG2207@1|root,COG2207@2|Bacteria,1V579@1239|Firmicutes,25B25@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
PNCOCPKN_00444	585394.RHOM_14150	0.0	871.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
PNCOCPKN_00445	585394.RHOM_14155	2.57e-171	479.0	COG1073@1|root,COG1073@2|Bacteria,1UXYN@1239|Firmicutes,24DU6@186801|Clostridia	186801|Clostridia	E	Alpha beta	aroD	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
PNCOCPKN_00446	585394.RHOM_14160	0.0	1170.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia	186801|Clostridia	C	NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
PNCOCPKN_00447	483218.BACPEC_01265	5.65e-160	448.0	COG0745@1|root,COG0745@2|Bacteria,1TT12@1239|Firmicutes,24AB1@186801|Clostridia,26A59@186813|unclassified Clostridiales	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PNCOCPKN_00448	515620.EUBELI_01522	2.98e-288	789.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia,25V38@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PNCOCPKN_00449	1256908.HMPREF0373_01468	3.4e-154	433.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,25VW7@186806|Eubacteriaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PNCOCPKN_00450	457412.RSAG_02436	0.0	1528.0	COG0577@1|root,COG0577@2|Bacteria,1TQ8P@1239|Firmicutes,25E38@186801|Clostridia,3WHE4@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
PNCOCPKN_00451	397288.C806_00497	0.0	1111.0	COG2199@1|root,COG3452@1|root,COG2199@2|Bacteria,COG3452@2|Bacteria,1V037@1239|Firmicutes,24YFW@186801|Clostridia,27IDA@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4,SBP_bac_3
PNCOCPKN_00452	515620.EUBELI_20648	3.57e-16	81.3	COG0840@1|root,COG5000@1|root,COG0840@2|Bacteria,COG5000@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,25VY7@186806|Eubacteriaceae	186801|Clostridia	NT	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
PNCOCPKN_00453	397288.C806_02914	5.9e-24	94.0	COG0242@1|root,COG0242@2|Bacteria,1V73T@1239|Firmicutes,24FT0@186801|Clostridia,27MB2@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins	def2	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
PNCOCPKN_00454	478749.BRYFOR_05625	2.97e-288	814.0	COG1609@1|root,COG1653@1|root,COG1609@2|Bacteria,COG1653@2|Bacteria,1V31R@1239|Firmicutes,249JU@186801|Clostridia	186801|Clostridia	K	solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_1,Peripla_BP_4,SBP_bac_1,SBP_bac_8
PNCOCPKN_00455	478749.BRYFOR_05624	1.04e-183	519.0	COG1840@1|root,COG1840@2|Bacteria,1U5IH@1239|Firmicutes	1239|Firmicutes	P	solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
PNCOCPKN_00456	478749.BRYFOR_05623	1.57e-191	537.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
PNCOCPKN_00457	478749.BRYFOR_05622	0.0	923.0	COG1178@1|root,COG1178@2|Bacteria,1TPMX@1239|Firmicutes,24A64@186801|Clostridia	186801|Clostridia	P	ABC-type Fe3 transport system permease component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
PNCOCPKN_00458	478749.BRYFOR_05621	1.39e-146	418.0	COG0584@1|root,COG0584@2|Bacteria,1V404@1239|Firmicutes,24EP5@186801|Clostridia	186801|Clostridia	C	Domain of unknown function	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	DUF4996,GDPD
PNCOCPKN_00459	478749.BRYFOR_05620	2.15e-89	270.0	COG1234@1|root,COG1234@2|Bacteria,1V1J7@1239|Firmicutes,24F18@186801|Clostridia	186801|Clostridia	S	Beta-lactamase superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2,UPF0227
PNCOCPKN_00460	936574.HMPREF1508_0912	4.87e-118	342.0	COG1285@1|root,COG1285@2|Bacteria,1V409@1239|Firmicutes,249SQ@186801|Clostridia	186801|Clostridia	E	MgtC SapB transporter	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
PNCOCPKN_00461	622312.ROSEINA2194_04392	4.68e-126	365.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
PNCOCPKN_00462	1410650.JHWL01000010_gene2770	2.77e-48	169.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,4BWYE@830|Butyrivibrio	186801|Clostridia	K	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
PNCOCPKN_00464	1256908.HMPREF0373_01323	2.05e-45	149.0	COG1476@1|root,COG1476@2|Bacteria,1UNYA@1239|Firmicutes	1239|Firmicutes	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PNCOCPKN_00465	1256908.HMPREF0373_01324	6.48e-73	223.0	2AI96@1|root,318PT@2|Bacteria,1V7JX@1239|Firmicutes,24M2N@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00467	515620.EUBELI_20549	0.0	950.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,25UVM@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PNCOCPKN_00468	515620.EUBELI_20548	0.0	1051.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,25UTB@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PNCOCPKN_00469	515620.EUBELI_20547	3.2e-62	194.0	COG1846@1|root,COG1846@2|Bacteria,1VGNE@1239|Firmicutes,25MX1@186801|Clostridia,25Z6W@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00470	1458462.JNLK01000001_gene1969	2.36e-21	85.1	2E7R6@1|root,3326H@2|Bacteria,1VGKC@1239|Firmicutes,24QSS@186801|Clostridia,27P7U@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00471	33035.JPJF01000004_gene1943	4.51e-273	757.0	COG1653@1|root,COG1653@2|Bacteria,1TPWV@1239|Firmicutes,25NJ2@186801|Clostridia,3Y1EP@572511|Blautia	186801|Clostridia	G	Domain of unknown function (DUF3502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3502
PNCOCPKN_00473	180332.JTGN01000009_gene4367	2.74e-183	514.0	COG4209@1|root,COG4209@2|Bacteria,1TQFY@1239|Firmicutes,24923@186801|Clostridia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
PNCOCPKN_00474	33035.JPJF01000004_gene1945	6.98e-178	499.0	COG0395@1|root,COG0395@2|Bacteria,1TP1G@1239|Firmicutes,247T2@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
PNCOCPKN_00475	33035.JPJF01000004_gene1946	2.54e-192	559.0	COG2972@1|root,COG2972@2|Bacteria,1U6WN@1239|Firmicutes,257VB@186801|Clostridia,3Y13A@572511|Blautia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
PNCOCPKN_00476	33035.JPJF01000004_gene1947	2.94e-155	461.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1UCUQ@1239|Firmicutes,24FD5@186801|Clostridia,3Y1DI@572511|Blautia	186801|Clostridia	KT	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
PNCOCPKN_00477	622312.ROSEINA2194_03393	0.0	1439.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia	186801|Clostridia	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
PNCOCPKN_00478	622312.ROSEINA2194_00266	1.01e-39	132.0	2E7R6@1|root,3326H@2|Bacteria,1VGKC@1239|Firmicutes,24QSS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00479	1410631.JHWZ01000013_gene1920	4.39e-146	462.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,27I9U@186928|unclassified Lachnospiraceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	DegV,HATPase_c,HD,HisKA,HisKA_7TM,Hpt,MASE3,Response_reg,dCache_1
PNCOCPKN_00480	397291.C804_05622	2.26e-57	187.0	COG0745@1|root,COG0745@2|Bacteria,1V566@1239|Firmicutes,25EMQ@186801|Clostridia,27TZD@186928|unclassified Lachnospiraceae	186801|Clostridia	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
PNCOCPKN_00481	585394.RHOM_14180	0.0	1029.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,2480C@186801|Clostridia	186801|Clostridia	M	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
PNCOCPKN_00482	585394.RHOM_14175	5.23e-233	642.0	COG1453@1|root,COG1453@2|Bacteria,1TSTA@1239|Firmicutes,249IP@186801|Clostridia	186801|Clostridia	C	aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
PNCOCPKN_00483	622312.ROSEINA2194_04026	3.79e-104	306.0	COG0546@1|root,COG0546@2|Bacteria,1V3YI@1239|Firmicutes,24CRF@186801|Clostridia	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
PNCOCPKN_00485	411459.RUMOBE_02462	2.05e-147	420.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,3Y0BE@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	ATP_bind_3,NAD_synthase,QueC
PNCOCPKN_00486	1280698.AUJS01000009_gene753	2.59e-156	441.0	COG1179@1|root,COG1179@2|Bacteria,1TQ7A@1239|Firmicutes,248RA@186801|Clostridia,27VIT@189330|Dorea	186801|Clostridia	H	COG COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and THIamine biosynthesis family 1	thiF	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
PNCOCPKN_00487	1235793.C809_00892	0.0	936.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia,27JM8@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
PNCOCPKN_00488	1235793.C809_00893	2.47e-188	527.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,27KXN@186928|unclassified Lachnospiraceae	186801|Clostridia	EP	Binding-protein-dependent transport system inner membrane component	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
PNCOCPKN_00489	1235793.C809_00894	8.03e-217	602.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,27II5@186928|unclassified Lachnospiraceae	186801|Clostridia	EP	N-terminal TM domain of oligopeptide transport permease C	oppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
PNCOCPKN_00490	1235793.C809_00895	4.8e-235	649.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,27JHK@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
PNCOCPKN_00491	748224.HMPREF9436_00019	4.52e-193	539.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WN2S@541000|Ruminococcaceae	186801|Clostridia	P	Oligopeptide/dipeptide transporter, C-terminal region	oppF	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
PNCOCPKN_00492	511680.BUTYVIB_00626	1.8e-149	449.0	COG0840@1|root,COG5000@1|root,COG0840@2|Bacteria,COG5000@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,4BX8J@830|Butyrivibrio	186801|Clostridia	NT	Methyl-accepting chemotaxis protein signaling domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
PNCOCPKN_00493	411461.DORFOR_02133	9.9e-280	771.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,27WEJ@189330|Dorea	186801|Clostridia	E	Sodium:alanine symporter family	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
PNCOCPKN_00494	622312.ROSEINA2194_00442	6.57e-282	775.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia	186801|Clostridia	S	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
PNCOCPKN_00495	1458462.JNLK01000001_gene4	4.27e-79	242.0	28HI8@1|root,2Z9QV@2|Bacteria,1UZZ2@1239|Firmicutes,24IH2@186801|Clostridia,27MEA@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4317
PNCOCPKN_00496	633147.Olsu_0367	0.000883	42.4	COG0583@1|root,COG0583@2|Bacteria,2HF43@201174|Actinobacteria,4CUXJ@84998|Coriobacteriia	84998|Coriobacteriia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PNCOCPKN_00497	515620.EUBELI_20098	1.57e-187	533.0	COG2206@1|root,COG2206@2|Bacteria,1TS2E@1239|Firmicutes,249S8@186801|Clostridia,25WUW@186806|Eubacteriaceae	186801|Clostridia	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
PNCOCPKN_00498	585394.RHOM_14165	1.61e-162	484.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,sCache_2,sCache_3_3
PNCOCPKN_00500	585394.RHOM_08995	1.17e-284	790.0	COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia	186801|Clostridia	H	cobalt chelatase	cbiK	-	4.99.1.3	ko:K02190	ko00860,ko01100,map00860,map01100	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiK
PNCOCPKN_00501	1256908.HMPREF0373_02031	3.25e-257	719.0	COG0614@1|root,COG0614@2|Bacteria,1TQ4U@1239|Firmicutes,249I2@186801|Clostridia,25UTP@186806|Eubacteriaceae	186801|Clostridia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
PNCOCPKN_00502	1256908.HMPREF0373_02030	2.04e-180	509.0	COG0609@1|root,COG0609@2|Bacteria,1TQXW@1239|Firmicutes,249TJ@186801|Clostridia,25VB9@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	btuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
PNCOCPKN_00503	1256908.HMPREF0373_02029	8.95e-184	521.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,25VKN@186806|Eubacteriaceae	186801|Clostridia	HP	K02013 iron complex transport system ATP-binding protein	fepC	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran,zf-like
PNCOCPKN_00504	592026.GCWU0000282_002961	0.0	1343.0	COG1112@1|root,COG1112@2|Bacteria,1TP20@1239|Firmicutes,24BMH@186801|Clostridia	186801|Clostridia	L	COG1112 Superfamily I DNA and RNA	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF2726
PNCOCPKN_00505	478749.BRYFOR_06207	1.32e-104	310.0	COG2186@1|root,COG2186@2|Bacteria,1V5UA@1239|Firmicutes,24BCM@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
PNCOCPKN_00506	478749.BRYFOR_06209	3.93e-255	708.0	COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,248PQ@186801|Clostridia	186801|Clostridia	EG	Gluconate	-	-	-	ko:K03299,ko:K06155,ko:K06156,ko:K06157	-	-	-	-	ko00000,ko02000	2.A.8,2.A.8.1.2,2.A.8.1.4,2.A.8.1.8	-	iHN637.CLJU_RS05690,iHN637.CLJU_RS13905	GntP_permease
PNCOCPKN_00507	457421.CBFG_01718	0.0	1025.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia	186801|Clostridia	EG	Belongs to the IlvD Edd family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
PNCOCPKN_00508	1123405.AUMM01000022_gene1917	5.81e-29	122.0	COG2971@1|root,COG2971@2|Bacteria,1V0VG@1239|Firmicutes,4HFJ0@91061|Bacilli,26P0S@186821|Sporolactobacillaceae	91061|Bacilli	G	BadF/BadG/BcrA/BcrD ATPase family	gspK	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
PNCOCPKN_00509	140626.JHWB01000009_gene1454	7.9e-116	338.0	COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,248HK@186801|Clostridia	186801|Clostridia	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
PNCOCPKN_00510	1280664.AUIX01000021_gene2964	3.78e-170	487.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,2481N@186801|Clostridia,4BX6M@830|Butyrivibrio	186801|Clostridia	G	Amidohydrolase family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
PNCOCPKN_00511	585394.RHOM_14935	0.0	972.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia	186801|Clostridia	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
PNCOCPKN_00512	585394.RHOM_14920	6e-227	628.0	COG0275@1|root,COG0275@2|Bacteria,1TP5R@1239|Firmicutes,248PH@186801|Clostridia	186801|Clostridia	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH2	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
PNCOCPKN_00513	411489.CLOL250_02329	3.22e-169	478.0	COG0214@1|root,COG0214@2|Bacteria,1TPSZ@1239|Firmicutes,248C1@186801|Clostridia,36DZ4@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
PNCOCPKN_00514	411489.CLOL250_02328	1.99e-76	234.0	COG0311@1|root,COG0311@2|Bacteria,1V3I6@1239|Firmicutes,24HRT@186801|Clostridia,36I0R@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS19495	SNO
PNCOCPKN_00515	469617.FUAG_02364	7.33e-48	168.0	COG0534@1|root,COG0534@2|Bacteria,37936@32066|Fusobacteria	32066|Fusobacteria	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PNCOCPKN_00516	483218.BACPEC_03086	7.68e-62	194.0	2BIDU@1|root,32CK4@2|Bacteria,1VDRI@1239|Firmicutes,24NJ9@186801|Clostridia,26BYT@186813|unclassified Clostridiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00517	622312.ROSEINA2194_00274	6.74e-181	509.0	COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,24B0E@186801|Clostridia	186801|Clostridia	M	Linear amide C-N hydrolase, choloylglycine hydrolase family protein	cbh	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
PNCOCPKN_00518	411474.COPEUT_02079	2.24e-115	341.0	COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,24B1W@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PNCOCPKN_00519	585394.RHOM_02250	5.31e-119	345.0	COG2364@1|root,COG2364@2|Bacteria,1US08@1239|Firmicutes,24DPK@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00520	1235793.C809_01339	3.3e-36	125.0	COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,24JAB@186801|Clostridia,27NWQ@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
PNCOCPKN_00521	642492.Clole_0471	3.45e-245	701.0	COG2234@1|root,COG2234@2|Bacteria,1TRWH@1239|Firmicutes,24BM1@186801|Clostridia	186801|Clostridia	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
PNCOCPKN_00522	1121115.AXVN01000103_gene864	1.18e-100	297.0	COG0454@1|root,COG0456@2|Bacteria,1V1I9@1239|Firmicutes,24GXQ@186801|Clostridia	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
PNCOCPKN_00523	622312.ROSEINA2194_00835	1.74e-30	110.0	COG2747@1|root,COG2747@2|Bacteria,1VFH9@1239|Firmicutes,24QZ8@186801|Clostridia	186801|Clostridia	KNU	Anti-sigma-28 factor, FlgM	flgM	-	-	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgM
PNCOCPKN_00524	585394.RHOM_00615	1.59e-58	187.0	2APQ2@1|root,31ETS@2|Bacteria,1V6HK@1239|Firmicutes,24KPZ@186801|Clostridia	186801|Clostridia	S	FlgN protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgN
PNCOCPKN_00525	585394.RHOM_00620	1.2e-302	840.0	COG1256@1|root,COG1256@2|Bacteria,1TPXH@1239|Firmicutes,249PE@186801|Clostridia	186801|Clostridia	N	TIGRFAM Flagellar hook-associated protein, FlgK	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
PNCOCPKN_00526	585394.RHOM_00625	1.89e-281	788.0	COG1256@1|root,COG1256@2|Bacteria,1TPXH@1239|Firmicutes,249PE@186801|Clostridia	186801|Clostridia	N	TIGRFAM Flagellar hook-associated protein, FlgK	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
PNCOCPKN_00527	585394.RHOM_00630	4.48e-234	660.0	COG1344@1|root,COG1344@2|Bacteria,1TPDT@1239|Firmicutes,248FN@186801|Clostridia	186801|Clostridia	N	Belongs to the bacterial flagellin family	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
PNCOCPKN_00528	585394.RHOM_00635	7.21e-78	234.0	COG1699@1|root,COG1699@2|Bacteria,1VA6Y@1239|Firmicutes,24QXE@186801|Clostridia	186801|Clostridia	S	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum	fliW	-	-	ko:K13626	-	-	-	-	ko00000,ko02035	-	-	-	FliW
PNCOCPKN_00529	585394.RHOM_00640	1.92e-35	121.0	COG1551@1|root,COG1551@2|Bacteria,1VEEF@1239|Firmicutes,24QPD@186801|Clostridia	186801|Clostridia	T	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
PNCOCPKN_00530	622312.ROSEINA2194_00379	3.48e-36	129.0	COG1334@1|root,COG1334@2|Bacteria,1VFRY@1239|Firmicutes,24QPX@186801|Clostridia	186801|Clostridia	N	PFAM Flagellar protein FlaG protein	flaG	-	-	ko:K06603	-	-	-	-	ko00000,ko02035	-	-	-	FlaG
PNCOCPKN_00531	585394.RHOM_00650	4.53e-289	831.0	COG1345@1|root,COG1345@2|Bacteria,1TQ66@1239|Firmicutes,248Q9@186801|Clostridia	186801|Clostridia	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
PNCOCPKN_00532	585394.RHOM_00655	1.14e-68	209.0	COG1516@1|root,COG1516@2|Bacteria,1VA8K@1239|Firmicutes,24MRW@186801|Clostridia	186801|Clostridia	N	flagellar protein flis	fliS	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
PNCOCPKN_00533	622312.ROSEINA2194_00383	6.53e-57	182.0	2CW8V@1|root,32SZ6@2|Bacteria,1VAWT@1239|Firmicutes,24N6N@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FlgN
PNCOCPKN_00534	622312.ROSEINA2194_00384	1.74e-137	396.0	COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia	186801|Clostridia	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
PNCOCPKN_00535	1235802.C823_01289	2.43e-162	468.0	COG4641@1|root,COG4641@2|Bacteria,1TR7G@1239|Firmicutes,249U5@186801|Clostridia,25Y3M@186806|Eubacteriaceae	186801|Clostridia	S	DUF based on E. rectale Gene description (DUF3880)	-	-	-	ko:K06320	-	-	-	-	ko00000	-	-	-	DUF3880,Glyco_trans_1_2
PNCOCPKN_00536	1410625.JHWK01000004_gene892	1.14e-166	479.0	COG4641@1|root,COG4641@2|Bacteria,1TS28@1239|Firmicutes,24E2J@186801|Clostridia,27T93@186928|unclassified Lachnospiraceae	186801|Clostridia	S	DUF based on E. rectale Gene description (DUF3880)	-	-	-	ko:K06320	-	-	-	-	ko00000	-	-	-	DUF3880,Glyco_trans_1_2
PNCOCPKN_00537	1235802.C823_01287	7.51e-120	360.0	COG4641@1|root,COG4641@2|Bacteria,1VEBC@1239|Firmicutes,24VD4@186801|Clostridia	186801|Clostridia	S	DUF based on E. rectale Gene description (DUF3880)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3880,Glyco_tranf_2_5,Glyco_trans_1_2
PNCOCPKN_00538	397287.C807_02816	6.59e-123	381.0	COG4641@1|root,COG4641@2|Bacteria,1UMWB@1239|Firmicutes,24CQX@186801|Clostridia,27P03@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
PNCOCPKN_00539	1235802.C823_01282	4.98e-120	358.0	COG1442@1|root,COG1442@2|Bacteria,1U6EG@1239|Firmicutes,24B83@186801|Clostridia,25YSI@186806|Eubacteriaceae	186801|Clostridia	M	Domain of unknown function (DUF4422)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4422,Glyco_transf_8
PNCOCPKN_00540	1410630.JNKP01000001_gene2217	3.37e-62	204.0	COG0463@1|root,COG0463@2|Bacteria,1UI7F@1239|Firmicutes	1239|Firmicutes	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PNCOCPKN_00541	585394.RHOM_00805	5.88e-131	406.0	COG1216@1|root,COG2230@1|root,COG1216@2|Bacteria,COG2230@2|Bacteria,1V06G@1239|Firmicutes,247WU@186801|Clostridia	186801|Clostridia	H	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_11,Methyltransf_23
PNCOCPKN_00542	140626.JHWB01000013_gene701	1.15e-100	307.0	COG0463@1|root,COG0463@2|Bacteria,1V8D0@1239|Firmicutes,24MDZ@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PNCOCPKN_00543	1235802.C823_01285	7.94e-95	283.0	COG1216@1|root,COG1216@2|Bacteria,1V5W3@1239|Firmicutes,24I8J@186801|Clostridia,25YID@186806|Eubacteriaceae	186801|Clostridia	S	Glycosyltransferase like family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_5
PNCOCPKN_00545	622312.ROSEINA2194_00398	1.1e-64	218.0	COG4641@1|root,COG4641@2|Bacteria,1V3QP@1239|Firmicutes,24I06@186801|Clostridia	186801|Clostridia	S	DUF based on E. rectale Gene description (DUF3880)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3880,Glyco_trans_1_2
PNCOCPKN_00546	1235798.C817_04730	4.22e-71	229.0	COG1442@1|root,COG1442@2|Bacteria,1VD8V@1239|Firmicutes,24U1C@186801|Clostridia	186801|Clostridia	M	Glycosyl transferase family 8	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_8
PNCOCPKN_00547	622312.ROSEINA2194_00415	9.01e-54	191.0	COG1215@1|root,COG1215@2|Bacteria,1UIFK@1239|Firmicutes,25EM1@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PNCOCPKN_00548	1235790.C805_03260	4.1e-149	446.0	COG0457@1|root,COG0457@2|Bacteria,1VPVA@1239|Firmicutes,24ZYS@186801|Clostridia	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00549	1235790.C805_03259	0.0	1071.0	COG0574@1|root,COG0574@2|Bacteria,1UJVW@1239|Firmicutes,24ASB@186801|Clostridia,25XXT@186806|Eubacteriaceae	186801|Clostridia	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
PNCOCPKN_00550	397287.C807_02820	1.34e-110	326.0	COG0500@1|root,COG2226@2|Bacteria,1UIRD@1239|Firmicutes,25FBI@186801|Clostridia	186801|Clostridia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
PNCOCPKN_00551	1235790.C805_03257	1.17e-90	271.0	COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,24JCU@186801|Clostridia,25WNH@186806|Eubacteriaceae	186801|Clostridia	S	Peptidase C26	-	-	-	-	-	-	-	-	-	-	-	-	PEP-utilizers,PPDK_N,Peptidase_C26
PNCOCPKN_00552	1235790.C805_03256	8.51e-154	435.0	COG1213@1|root,COG1213@2|Bacteria,1VEAC@1239|Firmicutes,25H83@186801|Clostridia,25YFM@186806|Eubacteriaceae	186801|Clostridia	M	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
PNCOCPKN_00553	1235790.C805_03255	3.19e-86	257.0	COG0529@1|root,COG0529@2|Bacteria,1TQXK@1239|Firmicutes,24GDY@186801|Clostridia,25WT7@186806|Eubacteriaceae	186801|Clostridia	P	Adenylylsulphate kinase	-	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
PNCOCPKN_00554	1235790.C805_03253	1.16e-132	382.0	COG1208@1|root,COG1208@2|Bacteria,1V316@1239|Firmicutes,24GJU@186801|Clostridia,25YFN@186806|Eubacteriaceae	186801|Clostridia	JM	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00555	1235790.C805_03251	1.34e-198	556.0	COG0451@1|root,COG0451@2|Bacteria,1TQW7@1239|Firmicutes,24BI6@186801|Clostridia,25VIS@186806|Eubacteriaceae	186801|Clostridia	GM	RmlD substrate binding domain	rfbG	-	4.2.1.45	ko:K01709	ko00520,map00520	-	R02426	RC00402	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
PNCOCPKN_00556	1235790.C805_03250	6.93e-163	458.0	COG1208@1|root,COG1208@2|Bacteria,1TPII@1239|Firmicutes,249GT@186801|Clostridia,25VFZ@186806|Eubacteriaceae	186801|Clostridia	JM	Nucleotidyl transferase	-	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
PNCOCPKN_00557	1235790.C805_03249	6.93e-275	757.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,25VRM@186806|Eubacteriaceae	186801|Clostridia	M	DegT/DnrJ/EryC1/StrS aminotransferase family	rfbH	-	1.17.1.1	ko:K12452	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
PNCOCPKN_00558	622312.ROSEINA2194_00395	1.85e-46	152.0	2C12Y@1|root,32STC@2|Bacteria,1VCPE@1239|Firmicutes,24Q1P@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00559	1256908.HMPREF0373_00408	6.7e-86	263.0	COG3547@1|root,COG3547@2|Bacteria,1TP4A@1239|Firmicutes,24A2F@186801|Clostridia,25VFW@186806|Eubacteriaceae	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
PNCOCPKN_00560	1414720.CBYM010000014_gene2764	4.81e-30	117.0	COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,247R6@186801|Clostridia,36DHN@31979|Clostridiaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
PNCOCPKN_00561	1203606.HMPREF1526_01810	6.05e-153	436.0	COG3935@1|root,COG3935@2|Bacteria,1TPPF@1239|Firmicutes,249NG@186801|Clostridia,36G7Y@31979|Clostridiaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_36,RepA_N
PNCOCPKN_00562	1203606.HMPREF1526_01809	2.45e-103	300.0	28I1B@1|root,2Z93C@2|Bacteria,1UIR3@1239|Firmicutes,24B9I@186801|Clostridia,36WWG@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF3801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3801
PNCOCPKN_00563	545696.HOLDEFILI_01137	0.0	1066.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,3VP0A@526524|Erysipelotrichia	526524|Erysipelotrichia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	T4SS-DNA_transf
PNCOCPKN_00564	1235835.C814_01636	2.05e-42	139.0	2CDEH@1|root,32RXK@2|Bacteria,1VA17@1239|Firmicutes,24MPR@186801|Clostridia,3WJZH@541000|Ruminococcaceae	186801|Clostridia	S	Maff2 family	-	-	-	-	-	-	-	-	-	-	-	-	Maff2
PNCOCPKN_00565	1235835.C814_01637	5.71e-203	562.0	28HUM@1|root,2Z81B@2|Bacteria,1TNZ2@1239|Firmicutes,248SU@186801|Clostridia,3WI02@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	TrbL
PNCOCPKN_00566	1232453.BAIF02000016_gene3110	1.14e-203	565.0	COG1032@1|root,COG1032@2|Bacteria,1TRY3@1239|Firmicutes,249Q1@186801|Clostridia,26APH@186813|unclassified Clostridiales	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00567	1235835.C814_01638	3.41e-80	238.0	COG3451@1|root,COG3451@2|Bacteria,1V74G@1239|Firmicutes	1239|Firmicutes	U	COG NOG33085 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	PrgI
PNCOCPKN_00568	742741.HMPREF9475_03956	0.0	1425.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,248ND@186801|Clostridia,21YD2@1506553|Lachnoclostridium	186801|Clostridia	U	COG COG3451 Type IV secretory pathway, VirB4 components	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
PNCOCPKN_00569	552398.HMPREF0866_01350	1.27e-94	285.0	COG3617@1|root,COG3645@1|root,COG3617@2|Bacteria,COG3645@2|Bacteria,1TPKA@1239|Firmicutes,24BSZ@186801|Clostridia,3WPRP@541000|Ruminococcaceae	186801|Clostridia	K	Phage antirepressor protein KilAC domain	-	-	-	-	-	-	-	-	-	-	-	-	ANT,Bro-N
PNCOCPKN_00570	748224.HMPREF9436_02620	5.33e-67	211.0	2B1HE@1|root,31TYD@2|Bacteria,1V8YM@1239|Firmicutes,24BZ8@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00571	1232453.BAIF02000016_gene3103	1.22e-225	624.0	COG0270@1|root,COG0270@2|Bacteria,1TPNE@1239|Firmicutes,24B1A@186801|Clostridia,26A94@186813|unclassified Clostridiales	186801|Clostridia	L	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
PNCOCPKN_00572	1235835.C814_01632	0.0	1120.0	COG0791@1|root,COG0791@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia,3WI8Q@541000|Ruminococcaceae	186801|Clostridia	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
PNCOCPKN_00573	1235835.C814_01631	1.52e-185	514.0	COG0175@1|root,COG0175@2|Bacteria,1UZK3@1239|Firmicutes,24CWM@186801|Clostridia,3WMXJ@541000|Ruminococcaceae	186801|Clostridia	EH	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PAPS_reduct
PNCOCPKN_00574	1235835.C814_01630	1.03e-45	149.0	2AF03@1|root,32VU8@2|Bacteria,1VCMK@1239|Firmicutes,24M0U@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4315)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4315
PNCOCPKN_00575	1235835.C814_01629	2.4e-96	288.0	28HUZ@1|root,2Z81G@2|Bacteria,1TS04@1239|Firmicutes,25FQK@186801|Clostridia,3WS68@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4366)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4366
PNCOCPKN_00576	1235835.C814_01628	0.0	1263.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,3WGKN@541000|Ruminococcaceae	186801|Clostridia	L	DNA topoisomerase III	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
PNCOCPKN_00577	1235835.C814_01626	2.97e-111	320.0	28MN7@1|root,2ZAXU@2|Bacteria,1V0SN@1239|Firmicutes,24CZZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00578	411467.BACCAP_02490	0.0	1151.0	COG2003@1|root,COG4734@1|root,COG2003@2|Bacteria,COG4734@2|Bacteria,1TNY7@1239|Firmicutes,249ZG@186801|Clostridia,26A29@186813|unclassified Clostridiales	186801|Clostridia	L	Domain of unknown function (DUF4316)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA,DUF3846,DUF4316,YodL
PNCOCPKN_00579	997830.HMPREF1124_1328	1.14e-56	194.0	28M5W@1|root,2ZAJK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00580	411467.BACCAP_02502	1.86e-303	830.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,2481D@186801|Clostridia,267V4@186813|unclassified Clostridiales	186801|Clostridia	U	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
PNCOCPKN_00581	411467.BACCAP_02503	1.06e-65	200.0	296J0@1|root,2ZTUJ@2|Bacteria,1V3IP@1239|Firmicutes,24H9K@186801|Clostridia,269DI@186813|unclassified Clostridiales	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
PNCOCPKN_00582	1226322.HMPREF1545_02565	1.95e-77	231.0	COG1396@1|root,COG1396@2|Bacteria,1V50Y@1239|Firmicutes,25BHS@186801|Clostridia,2N8I8@216572|Oscillospiraceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PNCOCPKN_00583	1226322.HMPREF1545_02567	8.78e-238	653.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,2N6PD@216572|Oscillospiraceae	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	-	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
PNCOCPKN_00584	742740.HMPREF9474_03075	1.32e-92	271.0	COG1595@1|root,COG1595@2|Bacteria,1UYZA@1239|Firmicutes,24HQK@186801|Clostridia,2219R@1506553|Lachnoclostridium	2|Bacteria	K	Sigma-70, region 4	phyR	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Response_reg,Sigma70_r4_2
PNCOCPKN_00585	1226325.HMPREF1548_06048	4.04e-52	164.0	2AJW5@1|root,31AIZ@2|Bacteria,1V7QN@1239|Firmicutes,24JQH@186801|Clostridia,36PDP@31979|Clostridiaceae	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
PNCOCPKN_00586	545696.HOLDEFILI_01184	0.0	965.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,3VNR9@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
PNCOCPKN_00589	622312.ROSEINA2194_01515	0.0	917.0	COG3408@1|root,COG3408@2|Bacteria,1TPX8@1239|Firmicutes,249BI@186801|Clostridia	186801|Clostridia	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
PNCOCPKN_00591	622312.ROSEINA2194_01517	1.32e-143	408.0	COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,2489I@186801|Clostridia	186801|Clostridia	O	FeS assembly ATPase SufC	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
PNCOCPKN_00592	622312.ROSEINA2194_01518	4.04e-205	569.0	COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,249IU@186801|Clostridia	186801|Clostridia	O	feS assembly protein SufB	-	-	-	ko:K07033	-	-	-	-	ko00000	-	-	-	UPF0051
PNCOCPKN_00593	1280681.AUJZ01000012_gene1135	7.94e-19	82.4	2ED22@1|root,2ZVQM@2|Bacteria,1W3EW@1239|Firmicutes,256YE@186801|Clostridia,4BZ46@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00594	585394.RHOM_02440	7.97e-98	288.0	COG1451@1|root,COG1451@2|Bacteria,1UJII@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
PNCOCPKN_00595	411474.COPEUT_02877	2.02e-17	75.1	2EG1V@1|root,339TV@2|Bacteria,1VKAZ@1239|Firmicutes,24UGV@186801|Clostridia	186801|Clostridia	S	COG NOG17973 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF4250
PNCOCPKN_00597	585394.RHOM_02455	1.51e-35	120.0	2EGE3@1|root,33A60@2|Bacteria,1VMF7@1239|Firmicutes,24UMV@186801|Clostridia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00598	1408306.JHXX01000009_gene3377	1.66e-94	292.0	COG0860@1|root,COG0860@2|Bacteria,1UY5Q@1239|Firmicutes,247Y6@186801|Clostridia,4BWSH@830|Butyrivibrio	186801|Clostridia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
PNCOCPKN_00599	585394.RHOM_02460	0.0	1009.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
PNCOCPKN_00600	585394.RHOM_02465	0.0	1093.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
PNCOCPKN_00601	585394.RHOM_02470	0.0	1092.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
PNCOCPKN_00602	585394.RHOM_02475	2.69e-207	575.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,24999@186801|Clostridia	186801|Clostridia	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
PNCOCPKN_00603	585394.RHOM_02480	4.52e-301	825.0	COG1362@1|root,COG1362@2|Bacteria,1TP6G@1239|Firmicutes,2486Y@186801|Clostridia	186801|Clostridia	E	M18 family aminopeptidase	apeA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M18
PNCOCPKN_00604	585394.RHOM_02485	1.43e-136	395.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
PNCOCPKN_00605	585394.RHOM_02490	5.18e-178	499.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
PNCOCPKN_00606	622312.ROSEINA2194_03472	3.49e-144	414.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,2484M@186801|Clostridia	186801|Clostridia	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
PNCOCPKN_00607	585394.RHOM_02500	6.4e-30	108.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsH	-	-	ko:K11184,ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
PNCOCPKN_00608	585394.RHOM_02505	1.32e-182	511.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,249SY@186801|Clostridia	186801|Clostridia	I	lipid kinase, YegS Rv2252 BmrU family	dagK	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
PNCOCPKN_00609	585394.RHOM_02510	1.4e-201	558.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia	186801|Clostridia	G	Fructose-1,6-bisphosphate aldolase, class II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
PNCOCPKN_00610	585394.RHOM_02515	0.0	1234.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia	186801|Clostridia	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
PNCOCPKN_00611	585394.RHOM_02520	9.27e-66	201.0	COG0347@1|root,COG0347@2|Bacteria,1V9Z5@1239|Firmicutes,24MNA@186801|Clostridia	186801|Clostridia	K	Belongs to the P(II) protein family	glnB1	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
PNCOCPKN_00612	585394.RHOM_02525	3.07e-283	774.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,247W1@186801|Clostridia	186801|Clostridia	P	Ammonium Transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,P-II
PNCOCPKN_00613	742765.HMPREF9457_03704	8.59e-32	115.0	COG1708@1|root,COG1708@2|Bacteria,1UKQY@1239|Firmicutes,25G1K@186801|Clostridia	186801|Clostridia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
PNCOCPKN_00614	877421.AUJT01000008_gene2695	1.51e-49	160.0	COG1669@1|root,COG1669@2|Bacteria,1VBZU@1239|Firmicutes,24VNT@186801|Clostridia,27PBK@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
PNCOCPKN_00615	1408323.JQKK01000008_gene2069	2.05e-55	176.0	COG1895@1|root,COG1895@2|Bacteria,1VG5F@1239|Firmicutes,24RT7@186801|Clostridia,27PUE@186928|unclassified Lachnospiraceae	186801|Clostridia	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
PNCOCPKN_00616	1095750.HMPREF9970_1658	8.47e-100	311.0	COG5044@1|root,COG5044@2|Bacteria,1VXKX@1239|Firmicutes,252J9@186801|Clostridia	186801|Clostridia	O	Rab GDP-dissociation inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00617	1095750.HMPREF9970_1659	6.75e-286	858.0	COG0515@1|root,COG3903@1|root,COG0515@2|Bacteria,COG3903@2|Bacteria,1TY16@1239|Firmicutes,24A3H@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,Pkinase
PNCOCPKN_00620	556261.HMPREF0240_04096	1.23e-16	75.1	COG5566@1|root,COG5566@2|Bacteria,1VK7Y@1239|Firmicutes,24SS6@186801|Clostridia,36MMH@31979|Clostridiaceae	186801|Clostridia	S	Mor transcription activator family	-	-	-	-	-	-	-	-	-	-	-	-	Mor
PNCOCPKN_00621	411483.FAEPRAA2165_02657	8.46e-49	162.0	COG3597@1|root,COG3597@2|Bacteria,1TSZW@1239|Firmicutes,249YT@186801|Clostridia,3WKSA@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF697,MMR_HSR1
PNCOCPKN_00622	397287.C807_03073	1.23e-12	62.4	2EIY3@1|root,33CP9@2|Bacteria,1VN11@1239|Firmicutes,24W71@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00624	585394.RHOM_02535	0.0	1374.0	COG5009@1|root,COG5009@2|Bacteria,1UI0H@1239|Firmicutes,25E95@186801|Clostridia	186801|Clostridia	M	penicillin-binding protein	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
PNCOCPKN_00625	585394.RHOM_02540	3.37e-124	357.0	COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,248W7@186801|Clostridia	186801|Clostridia	S	YigZ family	yvyE	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
PNCOCPKN_00627	622312.ROSEINA2194_01571	3.97e-102	303.0	COG3884@1|root,COG3884@2|Bacteria,1TRH5@1239|Firmicutes,24G5K@186801|Clostridia	186801|Clostridia	I	Acyl-ACP thioesterase	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Acyl-ACP_TE
PNCOCPKN_00628	585394.RHOM_02550	1.31e-158	449.0	COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,2498C@186801|Clostridia	186801|Clostridia	S	S1, RNA binding domain	cvfB	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1,S1_2
PNCOCPKN_00629	585394.RHOM_02555	3.88e-75	225.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia	186801|Clostridia	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
PNCOCPKN_00630	592026.GCWU0000282_001066	1.87e-06	47.8	2EI20@1|root,33BTH@2|Bacteria,1VQF2@1239|Firmicutes	1239|Firmicutes	S	Putative motility protein	-	-	-	-	-	-	-	-	-	-	-	-	YjfB_motility
PNCOCPKN_00631	585394.RHOM_02570	2.33e-159	460.0	COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG4991@2|Bacteria,1TRKG@1239|Firmicutes,249Y4@186801|Clostridia	186801|Clostridia	MT	NlpC p60 family protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3
PNCOCPKN_00632	585394.RHOM_14870	0.0	935.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,248DZ@186801|Clostridia	186801|Clostridia	T	carbon starvation protein CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
PNCOCPKN_00633	585394.RHOM_02575	8.72e-82	251.0	COG1922@1|root,COG1922@2|Bacteria,1V7RM@1239|Firmicutes,24HC8@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
PNCOCPKN_00634	622312.ROSEINA2194_01579	1.09e-142	410.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,25CBM@186801|Clostridia	186801|Clostridia	S	protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
PNCOCPKN_00635	585394.RHOM_02580	3.34e-246	677.0	COG2508@1|root,COG2508@2|Bacteria,1TTA0@1239|Firmicutes,248HN@186801|Clostridia	186801|Clostridia	QT	Psort location Cytoplasmic, score	cdaR_3	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30
PNCOCPKN_00636	585394.RHOM_02585	3.36e-138	395.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia	186801|Clostridia	D	cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
PNCOCPKN_00637	622312.ROSEINA2194_01582	1.05e-173	489.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,24AA6@186801|Clostridia	186801|Clostridia	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
PNCOCPKN_00638	585394.RHOM_02595	5.47e-134	397.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia	186801|Clostridia	D	Peptidase, M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
PNCOCPKN_00639	622312.ROSEINA2194_01585	3.48e-215	605.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia	186801|Clostridia	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
PNCOCPKN_00640	622312.ROSEINA2194_01586	2.34e-46	155.0	COG5652@1|root,COG5652@2|Bacteria,1VF6Q@1239|Firmicutes,24QQ8@186801|Clostridia	186801|Clostridia	S	PFAM VanZ family protein	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
PNCOCPKN_00641	585394.RHOM_02610	7.05e-227	627.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,247KU@186801|Clostridia	186801|Clostridia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
PNCOCPKN_00642	1408323.JQKK01000025_gene1380	1.17e-69	222.0	2EN4B@1|root,33FSE@2|Bacteria,1VPF9@1239|Firmicutes,24SXK@186801|Clostridia,27NCJ@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Tim44,zinc_ribbon_2
PNCOCPKN_00643	585394.RHOM_02620	2.79e-211	596.0	COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia	186801|Clostridia	L	virion core protein (lumpy skin disease virus)	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1
PNCOCPKN_00644	585394.RHOM_02625	6.08e-163	468.0	COG1645@1|root,COG1645@2|Bacteria,1TRYG@1239|Firmicutes,25F3V@186801|Clostridia	186801|Clostridia	S	bacterial-type flagellum-dependent swarming motility	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00645	585394.RHOM_02630	3.29e-42	153.0	COG1512@1|root,COG1512@2|Bacteria,1V8N5@1239|Firmicutes,24H2W@186801|Clostridia	186801|Clostridia	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
PNCOCPKN_00646	585394.RHOM_02635	2.15e-83	248.0	COG4492@1|root,COG4492@2|Bacteria,1VAJ9@1239|Firmicutes,24MTS@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0735 family	pheB	-	5.4.99.5	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4
PNCOCPKN_00647	622312.ROSEINA2194_01595	2.59e-237	658.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia	186801|Clostridia	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
PNCOCPKN_00648	658086.HMPREF0994_00444	1.69e-28	107.0	COG2198@1|root,COG2198@2|Bacteria,1VG8R@1239|Firmicutes,24JZF@186801|Clostridia,27PU8@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Hpt domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
PNCOCPKN_00649	585394.RHOM_02670	7.26e-73	226.0	COG1971@1|root,COG1971@2|Bacteria,1V25U@1239|Firmicutes	1239|Firmicutes	P	Probably functions as a manganese efflux pump	ytaF	-	-	-	-	-	-	-	-	-	-	-	Mntp
PNCOCPKN_00650	622312.ROSEINA2194_01607	5.19e-241	664.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia	186801|Clostridia	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
PNCOCPKN_00651	585394.RHOM_02740	0.0	2013.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia	186801|Clostridia	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS
PNCOCPKN_00652	585394.RHOM_02755	5.01e-207	585.0	COG2206@1|root,COG2206@2|Bacteria,1UUCI@1239|Firmicutes,24CPS@186801|Clostridia	186801|Clostridia	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
PNCOCPKN_00653	585394.RHOM_02760	2.56e-95	296.0	COG3773@1|root,COG3883@1|root,COG3773@2|Bacteria,COG3883@2|Bacteria,1V02Q@1239|Firmicutes,24CZW@186801|Clostridia	186801|Clostridia	M	Cell wall hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_2
PNCOCPKN_00654	622312.ROSEINA2194_04078	2.97e-267	733.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia	186801|Clostridia	I	Belongs to the thiolase family	thlA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
PNCOCPKN_00655	585394.RHOM_02770	2.14e-199	553.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
PNCOCPKN_00656	585394.RHOM_02775	4.52e-262	719.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia	186801|Clostridia	C	acyl-CoA dehydrogenase	bcd	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PNCOCPKN_00657	622312.ROSEINA2194_04075	2.29e-179	500.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia	186801|Clostridia	C	electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
PNCOCPKN_00658	622312.ROSEINA2194_04074	1.41e-240	662.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia	186801|Clostridia	C	electron transfer flavoprotein	etfA	-	1.3.1.108	ko:K03522,ko:K22432	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	ETF,ETF_alpha
PNCOCPKN_00659	1384066.JAGT01000001_gene1483	2.65e-19	92.0	COG4412@1|root,COG4412@2|Bacteria,1VJS1@1239|Firmicutes,24RVX@186801|Clostridia	186801|Clostridia	S	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00660	622312.ROSEINA2194_00831	1.85e-91	273.0	COG4684@1|root,COG4684@2|Bacteria,1V2ZW@1239|Firmicutes	1239|Firmicutes	S	ECF transporter, substrate-specific component	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
PNCOCPKN_00661	622312.ROSEINA2194_00831	9.83e-98	290.0	COG4684@1|root,COG4684@2|Bacteria,1V2ZW@1239|Firmicutes	1239|Firmicutes	S	ECF transporter, substrate-specific component	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
PNCOCPKN_00662	411462.DORLON_02376	2.08e-42	150.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,27WEW@189330|Dorea	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
PNCOCPKN_00663	742765.HMPREF9457_00198	3.54e-88	269.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,27WEW@189330|Dorea	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
PNCOCPKN_00664	411462.DORLON_02377	3.84e-72	248.0	COG3976@1|root,COG3976@2|Bacteria,1TR5A@1239|Firmicutes,25E6J@186801|Clostridia,27VY2@189330|Dorea	186801|Clostridia	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,Fer4_5
PNCOCPKN_00665	742765.HMPREF9457_00196	2.29e-39	136.0	COG3976@1|root,COG3976@2|Bacteria,1VENM@1239|Firmicutes,24RRX@186801|Clostridia,27WZB@189330|Dorea	186801|Clostridia	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
PNCOCPKN_00666	742765.HMPREF9457_00195	9.55e-38	139.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,27WG2@189330|Dorea	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
PNCOCPKN_00668	1280698.AUJS01000027_gene2309	6.65e-113	366.0	COG1196@1|root,COG1196@2|Bacteria,1UJ26@1239|Firmicutes,25EV1@186801|Clostridia,27WJD@189330|Dorea	186801|Clostridia	D	Penicillin-binding protein Tp47 domain a	-	-	-	-	-	-	-	-	-	-	-	-	DUF1533,FIVAR,FMN_bind,PBP-Tp47_a,PBP-Tp47_c
PNCOCPKN_00669	1410628.JNKS01000007_gene1428	7.76e-13	68.2	2BZT8@1|root,32W5F@2|Bacteria,1UGQC@1239|Firmicutes,24Q23@186801|Clostridia,27RY9@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
PNCOCPKN_00671	585394.RHOM_13050	4.08e-43	140.0	COG1609@1|root,COG1609@2|Bacteria,1VADF@1239|Firmicutes,24MXI@186801|Clostridia	186801|Clostridia	K	sporulation transcriptional regulator SpoIIID	spoIIID	-	-	ko:K06283	-	-	-	-	ko00000,ko03000	-	-	-	SpoIIID
PNCOCPKN_00672	622312.ROSEINA2194_00215	1.8e-103	301.0	2CAVT@1|root,304CC@2|Bacteria,1V4J6@1239|Firmicutes,24HQA@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2798
PNCOCPKN_00673	622312.ROSEINA2194_00211	0.0	966.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia	186801|Clostridia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
PNCOCPKN_00674	1121289.JHVL01000079_gene1189	1.49e-10	57.8	2E5UB@1|root,330IM@2|Bacteria,1VFEC@1239|Firmicutes,24R3P@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00675	500632.CLONEX_00839	1.14e-187	530.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
PNCOCPKN_00676	397290.C810_00824	7.42e-36	126.0	2AC9W@1|root,311UM@2|Bacteria,1V5SJ@1239|Firmicutes,24IEX@186801|Clostridia,27MBK@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00677	140626.JHWB01000009_gene1329	2.39e-169	480.0	COG1066@1|root,COG1066@2|Bacteria,1UIA9@1239|Firmicutes,25EF9@186801|Clostridia	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25
PNCOCPKN_00678	1235793.C809_02145	1.96e-25	100.0	2DINV@1|root,303RW@2|Bacteria,1V6BI@1239|Firmicutes,24HNZ@186801|Clostridia	186801|Clostridia	S	Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
PNCOCPKN_00679	1540257.JQMW01000011_gene2029	1.46e-107	331.0	COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia,36KE8@31979|Clostridiaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
PNCOCPKN_00680	1034347.CAHJ01000005_gene2492	1.17e-185	533.0	COG0270@1|root,COG0270@2|Bacteria,1TSNX@1239|Firmicutes,4HFAI@91061|Bacilli,1ZBQM@1386|Bacillus	91061|Bacilli	L	DNA (cytosine-5-)-methyltransferase activity	ddeI	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
PNCOCPKN_00681	643867.Ftrac_2142	4.38e-29	122.0	28MJP@1|root,2ZAW3@2|Bacteria,4NKRQ@976|Bacteroidetes,47TSU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00682	545696.HOLDEFILI_03630	2.08e-181	540.0	COG1131@1|root,COG1672@1|root,COG1131@2|Bacteria,COG1672@2|Bacteria,1V0HG@1239|Firmicutes	1239|Firmicutes	V	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_13
PNCOCPKN_00683	1235802.C823_06083	5.4e-65	211.0	COG5433@1|root,COG5433@2|Bacteria,1V0JK@1239|Firmicutes,249XC@186801|Clostridia	186801|Clostridia	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
PNCOCPKN_00684	411483.FAEPRAA2165_00991	2.27e-87	268.0	COG1215@1|root,COG1215@2|Bacteria,1V1CB@1239|Firmicutes,24EMU@186801|Clostridia,3WH23@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PNCOCPKN_00685	397290.C810_03894	5.56e-183	580.0	COG0860@1|root,COG4733@1|root,COG0860@2|Bacteria,COG4733@2|Bacteria,1UZ49@1239|Firmicutes,25F7R@186801|Clostridia,27JMX@186928|unclassified Lachnospiraceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,Big_2,GBS_Bsp-like,Glucosaminidase,RicinB_lectin_2,fn3
PNCOCPKN_00686	397290.C810_03819	7.98e-254	704.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia,27K11@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
PNCOCPKN_00687	397290.C810_03895	1.78e-28	132.0	COG4193@1|root,COG5492@1|root,COG4193@2|Bacteria,COG5492@2|Bacteria,1TRTM@1239|Firmicutes,24C4N@186801|Clostridia,27K3Z@186928|unclassified Lachnospiraceae	186801|Clostridia	G	SH3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Cadherin-like,Dockerin_1,Glucosaminidase,SH3_3
PNCOCPKN_00689	1235800.C819_00199	2.64e-95	293.0	COG0438@1|root,COG0438@2|Bacteria,1V76V@1239|Firmicutes,25IUU@186801|Clostridia,27NJE@186928|unclassified Lachnospiraceae	186801|Clostridia	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00690	552531.BIF_02151	3.47e-137	410.0	COG2244@1|root,COG2244@2|Bacteria,2IA1K@201174|Actinobacteria,4D0KU@85004|Bifidobacteriales	201174|Actinobacteria	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
PNCOCPKN_00691	585394.RHOM_12280	7e-134	389.0	COG1216@1|root,COG1216@2|Bacteria,1VAHM@1239|Firmicutes,24MBF@186801|Clostridia	186801|Clostridia	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PNCOCPKN_00692	585394.RHOM_12285	1.58e-150	428.0	COG1216@1|root,COG1216@2|Bacteria,1VBWR@1239|Firmicutes,24NB1@186801|Clostridia	186801|Clostridia	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PNCOCPKN_00693	585394.RHOM_12290	1.72e-152	436.0	COG1216@1|root,COG1216@2|Bacteria,1UD0A@1239|Firmicutes,24GXB@186801|Clostridia	186801|Clostridia	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	GNT-I,Glycos_transf_2
PNCOCPKN_00694	585394.RHOM_12295	1.85e-171	484.0	COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,25EDZ@186801|Clostridia	186801|Clostridia	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
PNCOCPKN_00695	585394.RHOM_12300	4.4e-209	585.0	COG0438@1|root,COG0438@2|Bacteria,1VE1G@1239|Firmicutes	1239|Firmicutes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
PNCOCPKN_00696	585394.RHOM_12305	6.34e-197	553.0	COG0438@1|root,COG0438@2|Bacteria,1UI11@1239|Firmicutes,24CV8@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glycos_transf_1
PNCOCPKN_00697	585394.RHOM_12310	9.01e-226	629.0	COG0438@1|root,COG0438@2|Bacteria,1V0JW@1239|Firmicutes,24CKB@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
PNCOCPKN_00700	585394.RHOM_12330	1.29e-120	359.0	2A542@1|root,30TSQ@2|Bacteria,1V4Q2@1239|Firmicutes,24ISW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00701	585394.RHOM_12335	5.53e-108	332.0	COG0489@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3944@2|Bacteria	2|Bacteria	M	capsule polysaccharide biosynthetic process	wzc	-	2.7.10.1,2.7.10.2	ko:K08252,ko:K08253,ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
PNCOCPKN_00702	585394.RHOM_12340	3.58e-281	775.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,24870@186801|Clostridia	186801|Clostridia	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
PNCOCPKN_00703	1235790.C805_00459	1.46e-104	341.0	COG2242@1|root,COG2242@2|Bacteria,1TPEE@1239|Firmicutes,24D9B@186801|Clostridia,25Y5N@186806|Eubacteriaceae	186801|Clostridia	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
PNCOCPKN_00704	585394.RHOM_12355	3.25e-264	728.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia	186801|Clostridia	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
PNCOCPKN_00705	585394.RHOM_12360	7.88e-138	396.0	COG1682@1|root,COG1682@2|Bacteria,1TQZF@1239|Firmicutes,248R0@186801|Clostridia	186801|Clostridia	GM	Transport permease protein	-	-	-	ko:K09692	ko02010,map02010	M00251	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.104	-	-	ABC2_membrane
PNCOCPKN_00706	585394.RHOM_12365	5.1e-125	357.0	COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,248VX@186801|Clostridia	186801|Clostridia	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02630,iHN637.CLJU_RS02745	dTDP_sugar_isom
PNCOCPKN_00707	585394.RHOM_12370	1.06e-200	556.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,247XE@186801|Clostridia	186801|Clostridia	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
PNCOCPKN_00708	585394.RHOM_12375	5.63e-253	694.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
PNCOCPKN_00709	585394.RHOM_12380	2.64e-145	436.0	2AJ90@1|root,319TX@2|Bacteria,1VFA5@1239|Firmicutes,25DCM@186801|Clostridia	186801|Clostridia	S	Glucosyl transferase GtrII	-	-	-	-	-	-	-	-	-	-	-	-	Glucos_trans_II
PNCOCPKN_00710	585394.RHOM_12385	2.05e-179	503.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,247PG@186801|Clostridia	186801|Clostridia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
PNCOCPKN_00711	585394.RHOM_12390	6.68e-52	164.0	COG1925@1|root,COG1925@2|Bacteria,1VA23@1239|Firmicutes,24N32@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
PNCOCPKN_00712	622312.ROSEINA2194_02611	4.67e-297	813.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
PNCOCPKN_00713	585394.RHOM_12400	1.75e-145	430.0	COG4856@1|root,COG4856@2|Bacteria,1UZEV@1239|Firmicutes,25CGI@186801|Clostridia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
PNCOCPKN_00714	585394.RHOM_12405	9.81e-166	469.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
PNCOCPKN_00715	585394.RHOM_12410	3.49e-164	468.0	28K89@1|root,2Z9W3@2|Bacteria,1V1PZ@1239|Firmicutes,24D2W@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00716	585394.RHOM_12415	1.1e-50	165.0	2DIZ6@1|root,32UC0@2|Bacteria,1VCGW@1239|Firmicutes,24Q40@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00717	585394.RHOM_12420	7.79e-65	200.0	2D61I@1|root,32TKA@2|Bacteria,1VB5H@1239|Firmicutes,24NZW@186801|Clostridia	186801|Clostridia	N	TIGRFAM flagellar operon protein	yvyF	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00718	585394.RHOM_12425	1e-76	239.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia	186801|Clostridia	S	ComF family	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
PNCOCPKN_00719	622312.ROSEINA2194_02619	3.41e-177	502.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia	186801|Clostridia	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PNCOCPKN_00720	585394.RHOM_12435	6.4e-192	536.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia	186801|Clostridia	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
PNCOCPKN_00721	622312.ROSEINA2194_02621	1.41e-172	483.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia	186801|Clostridia	S	Abc transporter	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
PNCOCPKN_00722	585394.RHOM_12445	0.0	1269.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
PNCOCPKN_00723	622312.ROSEINA2194_03005	1.54e-35	125.0	COG3951@1|root,COG3951@2|Bacteria,1VICK@1239|Firmicutes,24QXM@186801|Clostridia	186801|Clostridia	MNO	Flagellar rod assembly protein muramidase FlgJ	-	-	-	-	-	-	-	-	-	-	-	-	Rod-binding
PNCOCPKN_00724	585394.RHOM_12455	9.08e-139	398.0	COG4786@1|root,COG4786@2|Bacteria,1TT5Z@1239|Firmicutes,248M9@186801|Clostridia	186801|Clostridia	N	basal body rod protein	flgG	-	-	ko:K02390,ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
PNCOCPKN_00725	585394.RHOM_12460	8.36e-152	431.0	COG4786@1|root,COG4786@2|Bacteria,1TRFQ@1239|Firmicutes,24C2V@186801|Clostridia	186801|Clostridia	N	basal body rod protein	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
PNCOCPKN_00726	585394.RHOM_12465	7e-221	611.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia	186801|Clostridia	D	Cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
PNCOCPKN_00727	585394.RHOM_12045	4.34e-63	211.0	COG3274@1|root,COG3274@2|Bacteria	2|Bacteria	S	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
PNCOCPKN_00728	585394.RHOM_12025	3.24e-72	234.0	COG3594@1|root,COG3594@2|Bacteria,1VJ6T@1239|Firmicutes,24UK1@186801|Clostridia	186801|Clostridia	G	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
PNCOCPKN_00729	1123248.KB893314_gene3360	8.33e-62	202.0	COG0438@1|root,COG0438@2|Bacteria,4PN7G@976|Bacteroidetes,1J005@117747|Sphingobacteriia	976|Bacteroidetes	M	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
PNCOCPKN_00730	1469948.JPNB01000002_gene3304	9.14e-22	88.2	COG1396@1|root,COG1396@2|Bacteria,1VAEQ@1239|Firmicutes,24RMB@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PNCOCPKN_00731	585394.RHOM_12475	0.0	1769.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
PNCOCPKN_00732	585394.RHOM_12480	0.0	1223.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
PNCOCPKN_00733	585394.RHOM_12610	1.35e-251	694.0	COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia	186801|Clostridia	C	domain protein	norV	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Flavodoxin_5,Lactamase_B,Lactamase_B_2
PNCOCPKN_00734	585394.RHOM_12615	0.0	1536.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
PNCOCPKN_00735	585394.RHOM_12620	2.17e-52	165.0	2E3FD@1|root,32YE7@2|Bacteria,1VEE4@1239|Firmicutes,24QJ7@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TSCPD
PNCOCPKN_00736	585394.RHOM_12625	9.08e-124	354.0	COG0452@1|root,COG0452@2|Bacteria,1TQPT@1239|Firmicutes,24HE6@186801|Clostridia	186801|Clostridia	H	Dipicolinic acid synthetase, b subunit	spoVFB	-	-	ko:K06411	-	-	-	-	ko00000	-	-	-	Flavoprotein
PNCOCPKN_00737	585394.RHOM_12630	1.52e-145	416.0	COG0169@1|root,COG0169@2|Bacteria,1UHR5@1239|Firmicutes,25ETW@186801|Clostridia	186801|Clostridia	E	dipicolinic acid synthetase, A subunit	-	-	-	ko:K06410	-	-	-	-	ko00000	-	-	-	2-Hacid_dh_C,AdoHcyase_NAD,DpaA_N,IlvN
PNCOCPKN_00738	622312.ROSEINA2194_03033	3.55e-296	810.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia	186801|Clostridia	E	Belongs to the aspartokinase family	thrA	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
PNCOCPKN_00739	585394.RHOM_12645	8.79e-136	390.0	COG2908@1|root,COG2908@2|Bacteria,1TT6N@1239|Firmicutes,24A8X@186801|Clostridia	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
PNCOCPKN_00740	585394.RHOM_12650	7.89e-92	282.0	2C69W@1|root,2Z7HR@2|Bacteria,1TQNN@1239|Firmicutes,249G5@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4474)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4474
PNCOCPKN_00741	411470.RUMGNA_01046	1.47e-300	830.0	COG0246@1|root,COG0246@2|Bacteria,1TQ97@1239|Firmicutes,247TG@186801|Clostridia,3XYQY@572511|Blautia	186801|Clostridia	G	Mannitol dehydrogenase Rossmann domain	-	-	1.1.1.57	ko:K00040	ko00040,ko01100,map00040,map01100	M00061	R02454	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
PNCOCPKN_00742	658655.HMPREF0988_01291	3.86e-130	378.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1TPMG@1239|Firmicutes,25E9N@186801|Clostridia,27UHQ@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	ARD,AraC_binding,Cupin_2,HTH_18
PNCOCPKN_00743	658088.HMPREF0987_02461	1e-168	474.0	COG1402@1|root,COG1402@2|Bacteria,1UDUM@1239|Firmicutes,2494R@186801|Clostridia	186801|Clostridia	S	Creatinine amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Creatininase
PNCOCPKN_00744	658088.HMPREF0987_02460	7.06e-128	372.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
PNCOCPKN_00745	658088.HMPREF0987_02459	1.5e-266	737.0	COG2211@1|root,COG2211@2|Bacteria,1TRYR@1239|Firmicutes,25C8G@186801|Clostridia,27KBK@186928|unclassified Lachnospiraceae	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
PNCOCPKN_00746	658088.HMPREF0987_02458	3.05e-108	325.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1TPMG@1239|Firmicutes,24ISI@186801|Clostridia,27T9S@186928|unclassified Lachnospiraceae	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
PNCOCPKN_00747	877415.JNJQ01000002_gene2280	1.53e-230	638.0	COG1312@1|root,COG1312@2|Bacteria,1TP5F@1239|Firmicutes,3VPNW@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Catalyzes the dehydration of D-mannonate	uxuA	-	-	-	-	-	-	-	-	-	-	-	UxuA
PNCOCPKN_00748	585394.RHOM_12655	1.59e-108	323.0	COG1388@1|root,COG1388@2|Bacteria,1V4FC@1239|Firmicutes	1239|Firmicutes	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	LysM
PNCOCPKN_00749	585394.RHOM_12660	3.95e-124	358.0	COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes,24AGM@186801|Clostridia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	lrgB	-	-	-	-	-	-	-	-	-	-	-	LrgB
PNCOCPKN_00750	585394.RHOM_12665	4.74e-51	164.0	COG1380@1|root,COG1380@2|Bacteria,1VEN4@1239|Firmicutes,24MMB@186801|Clostridia	186801|Clostridia	S	LrgA family	lrgA	-	-	ko:K06518	-	-	-	-	ko00000,ko02000	1.E.14.2	-	-	LrgA
PNCOCPKN_00751	622312.ROSEINA2194_03041	4.35e-192	548.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1TR1R@1239|Firmicutes,24A67@186801|Clostridia	186801|Clostridia	CE	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
PNCOCPKN_00752	585394.RHOM_12675	6.15e-85	258.0	COG0727@1|root,COG0727@2|Bacteria,1TT6P@1239|Firmicutes,24BWS@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
PNCOCPKN_00753	1235800.C819_03424	7.97e-173	494.0	COG0657@1|root,COG0657@2|Bacteria,1VUQV@1239|Firmicutes,250IT@186801|Clostridia,27UKJ@186928|unclassified Lachnospiraceae	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
PNCOCPKN_00754	1226325.HMPREF1548_02199	6.2e-25	96.3	COG4942@1|root,COG4942@2|Bacteria,1VSWX@1239|Firmicutes	1239|Firmicutes	D	K03657 DNA helicase II ATP-dependent DNA helicase PcrA	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00755	658086.HMPREF0994_01172	2.02e-21	90.5	COG4942@1|root,COG4942@2|Bacteria,1V67C@1239|Firmicutes,25FCI@186801|Clostridia	186801|Clostridia	D	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
PNCOCPKN_00756	622312.ROSEINA2194_03055	3.89e-153	437.0	COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,247WV@186801|Clostridia	186801|Clostridia	P	Belongs to the nlpA lipoprotein family	metQ	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
PNCOCPKN_00757	585394.RHOM_12805	9.38e-129	369.0	COG2011@1|root,COG2011@2|Bacteria,1TRSY@1239|Firmicutes,24AZ9@186801|Clostridia	186801|Clostridia	P	ABC-type metal ion transport system permease component	metI	-	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
PNCOCPKN_00758	622312.ROSEINA2194_03057	9.3e-180	508.0	COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,248PZ@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
PNCOCPKN_00760	622312.ROSEINA2194_03059	4.02e-189	528.0	COG0583@1|root,COG0583@2|Bacteria,1TP3E@1239|Firmicutes,248HI@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PNCOCPKN_00761	585394.RHOM_12825	4.14e-150	429.0	COG1284@1|root,COG1284@2|Bacteria,1TRAU@1239|Firmicutes,249DE@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
PNCOCPKN_00762	622312.ROSEINA2194_00531	9.66e-68	209.0	2E06E@1|root,32VUE@2|Bacteria,1VCMY@1239|Firmicutes,24NKQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00765	1504823.CCMM01000008_gene907	1.81e-153	439.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	yeiI	-	2.7.1.15,2.7.1.45,2.7.1.83	ko:K00852,ko:K00874,ko:K16328	ko00030,ko00240,ko01100,ko01120,ko01200,map00030,map00240,map01100,map01120,map01200	M00061,M00308,M00631	R01051,R01541,R02750,R03315	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_24,PfkB
PNCOCPKN_00766	411489.CLOL250_01422	6.32e-05	43.5	2EMZ1@1|root,33FM6@2|Bacteria,1VMDZ@1239|Firmicutes,24X8Z@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00767	411489.CLOL250_01423	9.74e-235	651.0	COG0786@1|root,COG0786@2|Bacteria,1TQA4@1239|Firmicutes,247WX@186801|Clostridia,36EF4@31979|Clostridiaceae	186801|Clostridia	P	Catalyzes the sodium-dependent transport of glutamate	gltS	-	-	ko:K03312	-	-	-	-	ko00000,ko02000	2.A.27	-	-	Glt_symporter,NMT1_3
PNCOCPKN_00768	411489.CLOL250_01424	2.48e-122	360.0	COG2358@1|root,COG2358@2|Bacteria,1TPXW@1239|Firmicutes,2489U@186801|Clostridia,36I0C@31979|Clostridiaceae	186801|Clostridia	S	TRAP transporter solute receptor, TAXI family	bcsP	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
PNCOCPKN_00769	585394.RHOM_12905	0.0	868.0	COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,248K3@186801|Clostridia	186801|Clostridia	E	Dipeptidase	pepD	-	-	ko:K08659	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C69
PNCOCPKN_00770	140626.JHWB01000022_gene2128	2.64e-81	248.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24J27@186801|Clostridia	186801|Clostridia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
PNCOCPKN_00771	622312.ROSEINA2194_00248	5.61e-262	724.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PNCOCPKN_00772	622312.ROSEINA2194_00247	3.92e-228	636.0	COG4286@1|root,COG4286@2|Bacteria,1V2PW@1239|Firmicutes,248SR@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	UPF0160
PNCOCPKN_00773	642492.Clole_1528	4.42e-84	280.0	COG0840@1|root,COG3290@1|root,COG0840@2|Bacteria,COG3290@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Cache_3-Cache_2,MCPsignal
PNCOCPKN_00774	1280698.AUJS01000065_gene671	1.73e-179	514.0	COG4924@1|root,COG4924@2|Bacteria,1TRVG@1239|Firmicutes,24D0P@186801|Clostridia	186801|Clostridia	S	Protein of unknown function N-terminus (DUF3323)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2399,DUF3323
PNCOCPKN_00775	1280698.AUJS01000065_gene670	0.0	1652.0	COG1196@1|root,COG1196@2|Bacteria,1TPW9@1239|Firmicutes,247V7@186801|Clostridia	186801|Clostridia	D	Putative exonuclease SbcCD, C subunit	-	-	-	-	-	-	-	-	-	-	-	-	SbcCD_C
PNCOCPKN_00776	1280698.AUJS01000065_gene669	6.57e-219	610.0	28HUD@1|root,2Z813@2|Bacteria,1TUFV@1239|Firmicutes,24A4P@186801|Clostridia	186801|Clostridia	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2398
PNCOCPKN_00777	1280698.AUJS01000065_gene668	3.07e-286	791.0	2CC51@1|root,2Z7IU@2|Bacteria,1TQNI@1239|Firmicutes,24DDD@186801|Clostridia	186801|Clostridia	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2397
PNCOCPKN_00779	411459.RUMOBE_04229	2.57e-42	139.0	arCOG05874@1|root,2ZJ01@2|Bacteria,1VARV@1239|Firmicutes,24NY6@186801|Clostridia,3Y0H2@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00780	585394.RHOM_16355	6.97e-157	442.0	COG3279@1|root,COG3279@2|Bacteria,1V217@1239|Firmicutes,24GJ1@186801|Clostridia	186801|Clostridia	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
PNCOCPKN_00782	622312.ROSEINA2194_01256	1.33e-43	142.0	COG3355@1|root,COG3355@2|Bacteria,1UJUP@1239|Firmicutes,25FAE@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_36
PNCOCPKN_00783	622312.ROSEINA2194_01257	0.0	1057.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia	186801|Clostridia	U	COG COG3505 Type IV secretory pathway, VirD4 components	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf
PNCOCPKN_00784	622312.ROSEINA2194_01258	5.3e-248	694.0	COG0358@1|root,COG0358@2|Bacteria,1TQKP@1239|Firmicutes,247WJ@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3991,Toprim_2
PNCOCPKN_00785	622312.ROSEINA2194_01259	4.59e-300	859.0	COG0790@1|root,COG0790@2|Bacteria,1TS5X@1239|Firmicutes,248TS@186801|Clostridia	186801|Clostridia	KLT	Psort location	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
PNCOCPKN_00787	411474.COPEUT_02488	4.42e-68	210.0	2EYI4@1|root,33RRZ@2|Bacteria,1VT7Z@1239|Firmicutes,24Z92@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00788	658086.HMPREF0994_01287	2.45e-41	141.0	COG1848@1|root,COG1848@2|Bacteria,1VCDC@1239|Firmicutes,24P6P@186801|Clostridia,27UGP@186928|unclassified Lachnospiraceae	186801|Clostridia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
PNCOCPKN_00789	1235790.C805_02339	5.04e-06	47.4	2EK1N@1|root,33DS4@2|Bacteria,1VK49@1239|Firmicutes,252AT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00790	622312.ROSEINA2194_01263	6.83e-72	218.0	297FF@1|root,2ZCG2@2|Bacteria,1V2VZ@1239|Firmicutes,24GYA@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00792	622312.ROSEINA2194_01264	1.35e-147	416.0	COG0270@1|root,COG0270@2|Bacteria,1VSZI@1239|Firmicutes,24YBG@186801|Clostridia	186801|Clostridia	L	C-5 cytosine-specific DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	DNA_methylase
PNCOCPKN_00793	622312.ROSEINA2194_01266	1.74e-85	251.0	COG4734@1|root,COG4734@2|Bacteria,1VCQ0@1239|Firmicutes,24PDW@186801|Clostridia	186801|Clostridia	L	Domain of unknown function (DUF3846)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3846
PNCOCPKN_00794	397291.C804_05728	1.83e-34	119.0	2EA8K@1|root,330PF@2|Bacteria,1VFGQ@1239|Firmicutes,24T8A@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00795	622312.ROSEINA2194_01269	2.62e-166	464.0	28PM6@1|root,346EC@2|Bacteria,1W146@1239|Firmicutes,2534I@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00796	622312.ROSEINA2194_01270	4.66e-66	202.0	2EA8K@1|root,334D3@2|Bacteria,1VD6U@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00797	622312.ROSEINA2194_01271	1.3e-263	721.0	COG0791@1|root,COG0791@2|Bacteria,1UJUQ@1239|Firmicutes,25FAF@186801|Clostridia	186801|Clostridia	M	NlpC p60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
PNCOCPKN_00798	622312.ROSEINA2194_01272	4.05e-119	340.0	COG2105@1|root,COG2105@2|Bacteria,1VDAD@1239|Firmicutes,24G9Y@186801|Clostridia	186801|Clostridia	S	PFAM AIG2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
PNCOCPKN_00799	622312.ROSEINA2194_01273	1.47e-242	666.0	28HR1@1|root,2Z7YI@2|Bacteria,1TRNR@1239|Firmicutes,2486X@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Amidoligase_2
PNCOCPKN_00800	397291.C804_05719	0.0	1131.0	COG3451@1|root,COG3451@2|Bacteria,1TS2J@1239|Firmicutes,25EI6@186801|Clostridia,27IJC@186928|unclassified Lachnospiraceae	186801|Clostridia	U	Domain of unknown function DUF87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87
PNCOCPKN_00801	622312.ROSEINA2194_01276	6.74e-126	359.0	28HKG@1|root,2Z7VB@2|Bacteria,1TZFI@1239|Firmicutes,24BXG@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00802	622312.ROSEINA2194_01277	3.88e-60	185.0	2BXEN@1|root,32R17@2|Bacteria,1V7Y8@1239|Firmicutes,24SE0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00803	622312.ROSEINA2194_01278	0.0	932.0	COG0270@1|root,COG0270@2|Bacteria,1TR36@1239|Firmicutes,249XY@186801|Clostridia	1239|Firmicutes	L	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
PNCOCPKN_00804	622312.ROSEINA2194_01279	6.12e-197	546.0	28I46@1|root,2Z87R@2|Bacteria,1TQ13@1239|Firmicutes,249S3@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00805	622312.ROSEINA2194_01280	1.08e-73	221.0	2B05D@1|root,31SFX@2|Bacteria,1V79U@1239|Firmicutes,24KBJ@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3852
PNCOCPKN_00806	622312.ROSEINA2194_01281	3.42e-111	319.0	28J4N@1|root,2Z90I@2|Bacteria,1V0D6@1239|Firmicutes,24HMY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00807	622312.ROSEINA2194_01282	0.0	1082.0	COG1572@1|root,COG1572@2|Bacteria,1TR48@1239|Firmicutes,24ADC@186801|Clostridia	186801|Clostridia	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00809	622312.ROSEINA2194_01285	6e-95	280.0	28MSI@1|root,2ZB0V@2|Bacteria,1UZDN@1239|Firmicutes,24NJ1@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00810	622312.ROSEINA2194_01286	2.04e-123	352.0	28MX7@1|root,2ZB4B@2|Bacteria,1UYA5@1239|Firmicutes,24F22@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00811	622312.ROSEINA2194_01287	7.59e-89	261.0	2C3VQ@1|root,2ZQ9I@2|Bacteria,1V3RW@1239|Firmicutes,24HQ0@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4320
PNCOCPKN_00812	622312.ROSEINA2194_01288	4.76e-172	483.0	COG2064@1|root,COG2064@2|Bacteria,1TUMZ@1239|Firmicutes,2495N@186801|Clostridia	186801|Clostridia	NU	Psort location CytoplasmicMembrane, score	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	-
PNCOCPKN_00813	397291.C804_05705	9.18e-183	513.0	COG4965@1|root,COG4965@2|Bacteria,1TS4U@1239|Firmicutes,248K2@186801|Clostridia	186801|Clostridia	U	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00814	622312.ROSEINA2194_01291	0.0	890.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia	186801|Clostridia	U	Type II IV secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
PNCOCPKN_00815	397291.C804_05703	1.11e-147	421.0	COG0455@1|root,COG0455@2|Bacteria,1TPJA@1239|Firmicutes,24A7K@186801|Clostridia	186801|Clostridia	D	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA
PNCOCPKN_00816	622312.ROSEINA2194_01294	1.65e-183	512.0	COG3745@1|root,COG3745@2|Bacteria,1TQRH@1239|Firmicutes,24BZT@186801|Clostridia	186801|Clostridia	U	Flp pilus assembly protein CpaB	cpaB	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
PNCOCPKN_00817	622312.ROSEINA2194_02334	4.64e-78	233.0	COG1989@1|root,COG1989@2|Bacteria	2|Bacteria	NOU	aspartic-type endopeptidase activity	gspO	-	3.4.23.43	ko:K02278,ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
PNCOCPKN_00818	622312.ROSEINA2194_02333	6.92e-87	256.0	COG2088@1|root,COG2088@2|Bacteria,1VYH3@1239|Firmicutes,253N0@186801|Clostridia	186801|Clostridia	M	SpoVG	-	-	-	-	-	-	-	-	-	-	-	-	SpoVG
PNCOCPKN_00819	622312.ROSEINA2194_02332	1.07e-43	142.0	2E4MF@1|root,32ZGD@2|Bacteria,1VEIK@1239|Firmicutes,24QUQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00820	622312.ROSEINA2194_02331	5.05e-68	207.0	COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,24MVQ@186801|Clostridia	186801|Clostridia	D	Could be involved in septation	spoVG1	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
PNCOCPKN_00821	622312.ROSEINA2194_02330	5.74e-112	322.0	2DMZM@1|root,32UMJ@2|Bacteria	2|Bacteria	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	YodL
PNCOCPKN_00822	622312.ROSEINA2194_02329	7.94e-54	168.0	2CDYZ@1|root,3459B@2|Bacteria,1VZ76@1239|Firmicutes,2533N@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00823	622312.ROSEINA2194_02328	4.65e-58	180.0	COG2002@1|root,COG2002@2|Bacteria,1VB2K@1239|Firmicutes,24RSN@186801|Clostridia	186801|Clostridia	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00824	622312.ROSEINA2194_02327	8.17e-98	285.0	COG2002@1|root,COG2002@2|Bacteria,1V3PE@1239|Firmicutes,24IQG@186801|Clostridia	186801|Clostridia	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00825	397291.C804_05693	3.24e-210	584.0	COG0338@1|root,COG0338@2|Bacteria,1UBIY@1239|Firmicutes,248RN@186801|Clostridia,27TJ8@186928|unclassified Lachnospiraceae	186801|Clostridia	L	D12 class N6 adenine-specific DNA methyltransferase	dam	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
PNCOCPKN_00826	622312.ROSEINA2194_02324	1.74e-168	471.0	2DGTD@1|root,2ZX87@2|Bacteria,1V45H@1239|Firmicutes,24GH9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00828	622312.ROSEINA2194_02322	0.0	1065.0	2DBKH@1|root,2Z9T5@2|Bacteria,1TQWZ@1239|Firmicutes,24D49@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
PNCOCPKN_00829	397291.C804_05689	1.86e-90	270.0	2E7UB@1|root,3329C@2|Bacteria,1VHFQ@1239|Firmicutes,24SM4@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00831	622312.ROSEINA2194_02320	4.92e-163	459.0	2C8US@1|root,33EYV@2|Bacteria,1VRE4@1239|Firmicutes,24XSX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00832	585394.RHOM_01090	9.05e-271	749.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
PNCOCPKN_00833	585394.RHOM_01085	1.8e-202	563.0	COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,248SS@186801|Clostridia	186801|Clostridia	S	domain protein	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
PNCOCPKN_00834	585394.RHOM_01080	5.72e-180	520.0	COG0265@1|root,COG0265@2|Bacteria,1TTAZ@1239|Firmicutes,24BWH@186801|Clostridia	186801|Clostridia	O	PDZ DHR GLGF domain protein	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
PNCOCPKN_00835	585394.RHOM_01075	0.0	1197.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
PNCOCPKN_00836	622312.ROSEINA2194_02099	1.22e-154	435.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia	186801|Clostridia	T	response regulator receiver	srrA_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PNCOCPKN_00837	585394.RHOM_01065	3.33e-274	758.0	COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
PNCOCPKN_00838	1235798.C817_01435	7.82e-49	162.0	2EAJ6@1|root,334N3@2|Bacteria,1VFXU@1239|Firmicutes,24RPH@186801|Clostridia	186801|Clostridia	S	Toxin ToxN, type III toxin-antitoxin system	-	-	-	ko:K19167	-	-	-	-	ko00000,ko02048	-	-	-	ToxN_toxin
PNCOCPKN_00839	1280698.AUJS01000008_gene873	1.25e-58	182.0	COG3070@1|root,COG3070@2|Bacteria,1V42M@1239|Firmicutes,24JNV@186801|Clostridia,27WUX@189330|Dorea	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
PNCOCPKN_00840	658655.HMPREF0988_00013	9.94e-116	336.0	COG4832@1|root,COG4832@2|Bacteria,1TQC2@1239|Firmicutes,248YH@186801|Clostridia,27K28@186928|unclassified Lachnospiraceae	186801|Clostridia	S	GyrI-like small molecule binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
PNCOCPKN_00841	1410631.JHWZ01000001_gene860	2.33e-160	456.0	COG2378@1|root,COG2378@2|Bacteria,1TT23@1239|Firmicutes,248A8@186801|Clostridia,27K8J@186928|unclassified Lachnospiraceae	186801|Clostridia	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
PNCOCPKN_00842	585394.RHOM_14450	9.26e-109	315.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,24J9T@186801|Clostridia	186801|Clostridia	J	ribosomal protein l17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
PNCOCPKN_00843	585394.RHOM_14460	8.48e-216	597.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
PNCOCPKN_00844	585394.RHOM_14465	1.58e-132	376.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
PNCOCPKN_00845	622312.ROSEINA2194_02078	1.22e-74	224.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia	186801|Clostridia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
PNCOCPKN_00846	585394.RHOM_14475	3.76e-72	218.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
PNCOCPKN_00847	585394.RHOM_14490	6.91e-45	145.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
PNCOCPKN_00848	397288.C806_00699	1.21e-18	80.1	COG2163@1|root,COG2163@2|Bacteria,1VEPA@1239|Firmicutes,24UP0@186801|Clostridia	186801|Clostridia	J	COG2163 Ribosomal protein L14E L6E L27E	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00849	585394.RHOM_14500	2.38e-154	437.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia	186801|Clostridia	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
PNCOCPKN_00850	622312.ROSEINA2194_02071	1.63e-147	416.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
PNCOCPKN_00851	585394.RHOM_14510	3.47e-276	760.0	COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,248T9@186801|Clostridia	186801|Clostridia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
PNCOCPKN_00852	622312.ROSEINA2194_02069	1.42e-92	271.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
PNCOCPKN_00853	585394.RHOM_14520	3.04e-32	112.0	COG1841@1|root,COG1841@2|Bacteria	2|Bacteria	J	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	rpmD	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
PNCOCPKN_00854	585394.RHOM_14525	1.84e-106	308.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
PNCOCPKN_00855	622312.ROSEINA2194_02066	6.5e-73	219.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
PNCOCPKN_00856	585394.RHOM_14535	7.41e-120	343.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,2496R@186801|Clostridia	186801|Clostridia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
PNCOCPKN_00857	585394.RHOM_14545	2.87e-88	259.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
PNCOCPKN_00858	585394.RHOM_14550	4.1e-39	129.0	COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,24QR1@186801|Clostridia	186801|Clostridia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
PNCOCPKN_00859	585394.RHOM_14555	9.01e-121	345.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
PNCOCPKN_00860	1235790.C805_00242	7.38e-61	187.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,25WQ0@186806|Eubacteriaceae	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
PNCOCPKN_00861	585394.RHOM_14565	2.87e-76	228.0	COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,24H98@186801|Clostridia	186801|Clostridia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
PNCOCPKN_00862	622312.ROSEINA2194_02060	3.48e-53	167.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
PNCOCPKN_00863	585394.RHOM_14575	5.47e-34	117.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia	186801|Clostridia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
PNCOCPKN_00864	622312.ROSEINA2194_02058	2.11e-98	286.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
PNCOCPKN_00865	585394.RHOM_14585	1.69e-151	426.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia	186801|Clostridia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
PNCOCPKN_00866	622312.ROSEINA2194_02056	7.16e-82	243.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia	186801|Clostridia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
PNCOCPKN_00867	622312.ROSEINA2194_02055	4.17e-60	185.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,24JN3@186801|Clostridia	186801|Clostridia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
PNCOCPKN_00868	585394.RHOM_14600	7.19e-198	548.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
PNCOCPKN_00869	585394.RHOM_14605	1.07e-58	182.0	COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,24MN8@186801|Clostridia	186801|Clostridia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
PNCOCPKN_00870	622312.ROSEINA2194_02052	1.43e-128	367.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
PNCOCPKN_00871	622312.ROSEINA2194_02051	9.66e-151	425.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
PNCOCPKN_00872	585394.RHOM_14620	3.22e-65	199.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia	186801|Clostridia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
PNCOCPKN_00873	585394.RHOM_14630	3.92e-279	768.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia	186801|Clostridia	P	domain protein	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
PNCOCPKN_00874	585394.RHOM_14635	4.26e-262	728.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia	186801|Clostridia	P	Cation transport protein	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
PNCOCPKN_00875	1256908.HMPREF0373_01077	9.73e-194	538.0	COG1092@1|root,COG1092@2|Bacteria,1TPUD@1239|Firmicutes,2480X@186801|Clostridia,25VPS@186806|Eubacteriaceae	186801|Clostridia	H	S-adenosylmethionine-dependent methyltransferase	rlmL_1	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
PNCOCPKN_00876	585394.RHOM_14710	7.89e-186	521.0	COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,24956@186801|Clostridia	186801|Clostridia	P	Mg2 transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
PNCOCPKN_00877	585394.RHOM_14715	1.21e-81	246.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,24IB5@186801|Clostridia	186801|Clostridia	M	Acetyltransferase GNAT family	yncA	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
PNCOCPKN_00878	720554.Clocl_3524	4.04e-70	222.0	COG0637@1|root,COG0637@2|Bacteria,1V1DF@1239|Firmicutes,24DES@186801|Clostridia,3WS73@541000|Ruminococcaceae	186801|Clostridia	S	IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
PNCOCPKN_00879	411468.CLOSCI_03983	1.16e-91	274.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,24DG3@186801|Clostridia,21ZN5@1506553|Lachnoclostridium	186801|Clostridia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
PNCOCPKN_00880	1235799.C818_03344	7.93e-104	311.0	COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,248AC@186801|Clostridia,27IRB@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
PNCOCPKN_00881	585394.RHOM_14750	7.73e-93	280.0	2AYHW@1|root,31QMC@2|Bacteria,1V6S7@1239|Firmicutes,24NBV@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	TraX
PNCOCPKN_00882	622312.ROSEINA2194_02031	2.78e-157	442.0	COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,24DII@186801|Clostridia	186801|Clostridia	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
PNCOCPKN_00883	585394.RHOM_06725	1.25e-195	577.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
PNCOCPKN_00885	1280688.AUJB01000010_gene2801	1.73e-45	159.0	COG0507@1|root,COG0507@2|Bacteria,1VAZW@1239|Firmicutes,24NP3@186801|Clostridia,3NI77@46205|Pseudobutyrivibrio	186801|Clostridia	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00886	585394.RHOM_14775	6.94e-129	371.0	COG1028@1|root,COG1028@2|Bacteria,1TZY6@1239|Firmicutes,248QZ@186801|Clostridia	186801|Clostridia	IQ	Oxidoreductase, short chain dehydrogenase reductase family protein	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
PNCOCPKN_00887	585394.RHOM_14780	0.0	1228.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	glgX	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
PNCOCPKN_00888	33035.JPJF01000028_gene2808	1.69e-126	364.0	COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,248NY@186801|Clostridia,3XZRB@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	fucA	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
PNCOCPKN_00889	622312.ROSEINA2194_02025	1.06e-147	429.0	COG4677@1|root,COG4677@2|Bacteria,1UYI6@1239|Firmicutes,24B29@186801|Clostridia	186801|Clostridia	G	Pectinesterase	-	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Pectinesterase
PNCOCPKN_00890	585394.RHOM_14795	1.38e-19	79.7	2DRBT@1|root,33B4Z@2|Bacteria,1VMZQ@1239|Firmicutes,24UIT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00891	397291.C804_00046	3.8e-120	357.0	COG1266@1|root,COG1266@2|Bacteria,1UYS2@1239|Firmicutes,24BKW@186801|Clostridia,27KG8@186928|unclassified Lachnospiraceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
PNCOCPKN_00892	411474.COPEUT_02349	1.4e-103	310.0	COG3868@1|root,COG3868@2|Bacteria,1V4J5@1239|Firmicutes,24GI7@186801|Clostridia	186801|Clostridia	M	Glycoside-hydrolase family GH114	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_114
PNCOCPKN_00893	411474.COPEUT_00477	1.27e-125	369.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,247X1@186801|Clostridia	186801|Clostridia	EG	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PNCOCPKN_00894	585394.RHOM_01030	1.86e-287	785.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
PNCOCPKN_00895	585394.RHOM_01025	0.0	1373.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia	186801|Clostridia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
PNCOCPKN_00896	585394.RHOM_01020	7.42e-102	295.0	COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,24FQN@186801|Clostridia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
PNCOCPKN_00897	585394.RHOM_01010	5.46e-89	261.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia	186801|Clostridia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
PNCOCPKN_00898	585394.RHOM_00985	0.0	2254.0	COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
PNCOCPKN_00899	585394.RHOM_00980	0.0	2360.0	COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
PNCOCPKN_00905	1298920.KI911353_gene1794	1.66e-76	262.0	COG2972@1|root,COG2972@2|Bacteria,1VS0D@1239|Firmicutes,24YHS@186801|Clostridia,221U8@1506553|Lachnoclostridium	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase
PNCOCPKN_00906	1226325.HMPREF1548_02292	1.37e-237	680.0	COG3534@1|root,COG3534@2|Bacteria,1TPG2@1239|Firmicutes,24AVP@186801|Clostridia	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-L-AF_C,CBM_4_9,Cadherin-like,Laminin_G_3
PNCOCPKN_00907	1232449.BAHV02000002_gene85	1.61e-151	468.0	COG5002@1|root,COG5002@2|Bacteria,1UM03@1239|Firmicutes,24F2S@186801|Clostridia,26CT2@186813|unclassified Clostridiales	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PNCOCPKN_00908	1226325.HMPREF1548_06783	1.2e-131	377.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,36DZG@31979|Clostridiaceae	186801|Clostridia	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PNCOCPKN_00909	1280694.AUJQ01000010_gene2535	5.01e-150	428.0	COG1533@1|root,COG1533@2|Bacteria,1TSS2@1239|Firmicutes,248SB@186801|Clostridia,3NI14@46205|Pseudobutyrivibrio	186801|Clostridia	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
PNCOCPKN_00910	397287.C807_02675	4.96e-55	177.0	COG5658@1|root,COG5658@2|Bacteria,1VB6E@1239|Firmicutes,24MSY@186801|Clostridia,27NNV@186928|unclassified Lachnospiraceae	186801|Clostridia	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	SdpI
PNCOCPKN_00911	411467.BACCAP_02128	1.49e-89	270.0	28N6T@1|root,2ZBBM@2|Bacteria,1TS9F@1239|Firmicutes,24DPE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00912	1408436.JHXY01000019_gene1391	2.24e-136	394.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,24ADT@186801|Clostridia,25W58@186806|Eubacteriaceae	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
PNCOCPKN_00913	1280681.AUJZ01000005_gene3017	7.5e-111	336.0	COG0639@1|root,COG0639@2|Bacteria,1V2F7@1239|Firmicutes,24H5G@186801|Clostridia,4BWBP@830|Butyrivibrio	186801|Clostridia	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
PNCOCPKN_00914	515620.EUBELI_20270	2.22e-85	254.0	COG2606@1|root,COG2606@2|Bacteria,1V3MU@1239|Firmicutes,24HH2@186801|Clostridia,25W9B@186806|Eubacteriaceae	186801|Clostridia	S	Aminoacyl-tRNA editing domain	EbsC	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
PNCOCPKN_00915	515620.EUBELI_20602	1.2e-51	164.0	2CG7V@1|root,32S3C@2|Bacteria,1UIG6@1239|Firmicutes,25EMK@186801|Clostridia,25ZVA@186806|Eubacteriaceae	186801|Clostridia	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4298,Dabb
PNCOCPKN_00916	411489.CLOL250_01927	0.0	892.0	COG1757@1|root,COG1757@2|Bacteria,1TP8A@1239|Firmicutes,247V4@186801|Clostridia,36EFF@31979|Clostridiaceae	186801|Clostridia	C	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
PNCOCPKN_00917	585394.RHOM_05920	3.92e-137	409.0	COG1132@1|root,COG1132@2|Bacteria,1UHQP@1239|Firmicutes,25E4H@186801|Clostridia	186801|Clostridia	V	abc transporter atp-binding protein	cydC	-	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
PNCOCPKN_00918	397290.C810_02249	1.73e-35	122.0	COG5577@1|root,COG5577@2|Bacteria,1TU9X@1239|Firmicutes,25IH5@186801|Clostridia,27S9B@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Coat F domain	-	-	-	-	-	-	-	-	-	-	-	-	Coat_F
PNCOCPKN_00919	397290.C810_02248	5.99e-21	84.0	29VDD@1|root,325Y2@2|Bacteria,1UHHD@1239|Firmicutes,25JIV@186801|Clostridia,27SCF@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00920	585394.RHOM_05970	1.64e-210	601.0	COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg,SnoaL_3
PNCOCPKN_00921	1163671.JAGI01000002_gene2184	1.01e-53	184.0	COG0037@1|root,COG0607@1|root,COG0037@2|Bacteria,COG0607@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia,36DIN@31979|Clostridiaceae	186801|Clostridia	H	Belongs to the TtcA family	ttcA	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3,Rhodanese
PNCOCPKN_00922	585394.RHOM_04810	8.84e-62	201.0	COG3773@1|root,COG3773@2|Bacteria,1VHG1@1239|Firmicutes,24SYE@186801|Clostridia	186801|Clostridia	M	COG3773 Cell wall hydrolyses involved in spore germination	-	-	3.5.1.28	ko:K01449	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Hydrolase_2
PNCOCPKN_00924	585394.RHOM_08970	4.02e-39	131.0	COG2158@1|root,COG2158@2|Bacteria	2|Bacteria	S	Cysteine-rich small domain	cbiA	-	-	ko:K07162	-	-	-	-	ko00000	-	-	-	zf-like
PNCOCPKN_00925	1120746.CCNL01000008_gene565	3.97e-96	288.0	COG2243@1|root,COG2243@2|Bacteria	2|Bacteria	H	precorrin-2 c20-methyltransferase	cobI	-	2.1.1.130,2.1.1.151,4.99.1.3	ko:K02190,ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05807,R05808	RC00003,RC01012,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
PNCOCPKN_00926	397290.C810_02927	3.53e-181	526.0	COG1797@1|root,COG2158@1|root,COG1797@2|Bacteria,COG2158@2|Bacteria,1TNY2@1239|Firmicutes,247PU@186801|Clostridia,27IYT@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
PNCOCPKN_00927	1120746.CCNL01000008_gene555	1.99e-239	686.0	COG2099@1|root,COG2241@1|root,COG2242@1|root,COG2099@2|Bacteria,COG2241@2|Bacteria,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	cobK	-	1.3.1.106,1.3.1.54,1.3.1.76,2.1.1.131,2.1.1.132,2.1.1.196,2.1.1.289,3.7.1.12,4.99.1.4	ko:K00595,ko:K02191,ko:K02304,ko:K03399,ko:K05895,ko:K05934,ko:K13541	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947,R05149,R05150,R05180,R05809,R05812,R05813,R07772,R07774,R07775	RC00003,RC01012,RC01034,RC01279,RC01280,RC01293,RC01545,RC02052,RC02053,RC02054,RC02097,RC03471	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15725	CbiJ,Methyltransf_31,TP_methylase
PNCOCPKN_00928	1120746.CCNL01000008_gene554	1.99e-128	370.0	COG1010@1|root,COG1010@2|Bacteria	2|Bacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cobJ	-	2.1.1.131,2.1.1.133,2.1.1.271,3.7.1.12,6.3.5.10	ko:K02232,ko:K05934,ko:K05936,ko:K13541	ko00860,ko01100,map00860,map01100	M00122	R05180,R05181,R05225,R05809,R05810,R07772	RC00003,RC00010,RC01293,RC01294,RC01302,RC01545,RC02049,RC02097,RC03471	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiC,TP_methylase
PNCOCPKN_00929	1469948.JPNB01000001_gene2323	1.29e-90	287.0	COG2073@1|root,COG2073@2|Bacteria,1TPYM@1239|Firmicutes,247JW@186801|Clostridia,36DM5@31979|Clostridiaceae	186801|Clostridia	H	Cobalamin biosynthesis protein cbiG	cbiG	-	3.7.1.12	ko:K02189	ko00860,ko01100,map00860,map01100	-	R07772	RC01545,RC02097	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS15705	CbiG_C,CbiG_N,CbiG_mid
PNCOCPKN_00930	622312.ROSEINA2194_01854	3.25e-135	388.0	COG2875@1|root,COG2875@2|Bacteria,1TP6J@1239|Firmicutes,248IZ@186801|Clostridia	186801|Clostridia	H	precorrin-4 C(11)-methyltransferase	cobM	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
PNCOCPKN_00931	622312.ROSEINA2194_01855	3.36e-168	483.0	COG1903@1|root,COG1903@2|Bacteria,1TQ3M@1239|Firmicutes,248AK@186801|Clostridia	186801|Clostridia	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
PNCOCPKN_00932	585394.RHOM_09030	2.78e-224	639.0	COG0079@1|root,COG2082@1|root,COG0079@2|Bacteria,COG2082@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia	186801|Clostridia	E	PFAM Aminotransferase class I and II	cobD_2	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
PNCOCPKN_00933	1235794.C811_00567	3.02e-18	93.6	2EAQP@1|root,334SX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
PNCOCPKN_00935	1235800.C819_02309	3.39e-41	155.0	2BCEZ@1|root,3260K@2|Bacteria,1URZY@1239|Firmicutes,259XQ@186801|Clostridia,27QI3@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00936	622312.ROSEINA2194_00099	2.06e-38	138.0	2B7HH@1|root,320MM@2|Bacteria,1V7BY@1239|Firmicutes,24KSD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00937	411469.EUBHAL_00686	2.33e-35	120.0	2EC3Y@1|root,3362U@2|Bacteria,1VF1Z@1239|Firmicutes,24QVE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00938	411459.RUMOBE_00759	3.67e-46	148.0	2E3HI@1|root,32YG4@2|Bacteria,1VHJH@1239|Firmicutes,24V52@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00939	1256908.HMPREF0373_00535	1.15e-76	243.0	COG1522@1|root,COG2865@1|root,COG1522@2|Bacteria,COG2865@2|Bacteria,1TRTZ@1239|Firmicutes,25CHW@186801|Clostridia,25WTS@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_11,HTH_24
PNCOCPKN_00940	1280698.AUJS01000017_gene1837	1.22e-110	331.0	COG1522@1|root,COG2865@1|root,COG1522@2|Bacteria,COG2865@2|Bacteria,1TRTZ@1239|Firmicutes,25CHW@186801|Clostridia,27W54@189330|Dorea	186801|Clostridia	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_11,HTH_24
PNCOCPKN_00941	1294142.CINTURNW_3431	5.18e-314	867.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia,36DVT@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
PNCOCPKN_00942	585394.RHOM_03115	5.83e-64	197.0	COG1917@1|root,COG1917@2|Bacteria,1VCF2@1239|Firmicutes,25BAE@186801|Clostridia	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
PNCOCPKN_00943	622312.ROSEINA2194_02021	2.46e-189	536.0	COG0738@1|root,COG0738@2|Bacteria,1UZWI@1239|Firmicutes,24H3U@186801|Clostridia	186801|Clostridia	G	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PNCOCPKN_00944	585394.RHOM_03110	3.13e-162	463.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,24BWQ@186801|Clostridia	186801|Clostridia	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
PNCOCPKN_00945	585394.RHOM_03105	2.6e-111	329.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V1DC@1239|Firmicutes,24GJV@186801|Clostridia	186801|Clostridia	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
PNCOCPKN_00946	585394.RHOM_03100	2.08e-218	619.0	COG2972@1|root,COG2972@2|Bacteria,1TSF9@1239|Firmicutes,2499Y@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase
PNCOCPKN_00947	585394.RHOM_03095	2.18e-60	191.0	2CPN3@1|root,32SJG@2|Bacteria,1VASE@1239|Firmicutes,24KG6@186801|Clostridia	186801|Clostridia	S	YcxB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
PNCOCPKN_00948	585394.RHOM_03090	9.42e-268	738.0	COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DctM
PNCOCPKN_00949	585394.RHOM_03085	1.59e-100	293.0	COG3090@1|root,COG3090@2|Bacteria,1V1US@1239|Firmicutes,24G5M@186801|Clostridia	186801|Clostridia	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
PNCOCPKN_00950	585394.RHOM_03080	5.67e-217	605.0	COG1638@1|root,COG1638@2|Bacteria,1TSSW@1239|Firmicutes,24DW9@186801|Clostridia	186801|Clostridia	G	TRAP transporter solute receptor, DctP family	-	-	-	-	-	-	-	-	-	-	-	-	DctP,TAT_signal
PNCOCPKN_00951	478749.BRYFOR_06633	1.71e-151	429.0	COG0730@1|root,COG0730@2|Bacteria,1TRFG@1239|Firmicutes,24AEX@186801|Clostridia	186801|Clostridia	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
PNCOCPKN_00952	411459.RUMOBE_02060	4.68e-63	196.0	COG1846@1|root,COG1846@2|Bacteria,1V749@1239|Firmicutes,24KYW@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
PNCOCPKN_00953	483218.BACPEC_02515	3.85e-262	734.0	COG1132@1|root,COG1132@2|Bacteria,1TPTK@1239|Firmicutes,249W7@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PNCOCPKN_00954	515620.EUBELI_20433	6.95e-298	828.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,25URG@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
PNCOCPKN_00955	483218.BACPEC_02513	1.71e-79	239.0	COG1846@1|root,COG1846@2|Bacteria,1V8Z3@1239|Firmicutes,24I7U@186801|Clostridia,26BAN@186813|unclassified Clostridiales	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
PNCOCPKN_00956	1392493.JIAB01000001_gene729	3.38e-308	842.0	COG1350@1|root,COG1350@2|Bacteria,1UI01@1239|Firmicutes,25E8Q@186801|Clostridia,27J2Z@186928|unclassified Lachnospiraceae	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
PNCOCPKN_00957	397291.C804_04903	9.42e-217	676.0	COG0419@1|root,COG1121@1|root,COG0419@2|Bacteria,COG1121@2|Bacteria,1TPCS@1239|Firmicutes,24A22@186801|Clostridia,27JHC@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Putative exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
PNCOCPKN_00958	1235802.C823_05147	2.83e-179	511.0	COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,248VE@186801|Clostridia,25VTM@186806|Eubacteriaceae	186801|Clostridia	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
PNCOCPKN_00959	445972.ANACOL_01323	2.22e-43	156.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,3WHT6@541000|Ruminococcaceae	186801|Clostridia	P	E1-E2 ATPase	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
PNCOCPKN_00960	1280673.AUJJ01000036_gene1542	1.55e-154	450.0	COG2312@1|root,COG2312@2|Bacteria,1V2ED@1239|Firmicutes,24BHP@186801|Clostridia,4BXEN@830|Butyrivibrio	186801|Clostridia	S	Erythromycin esterase	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Erythro_esteras
PNCOCPKN_00961	1321784.HMPREF1987_01012	1.21e-79	244.0	COG0716@1|root,COG1143@1|root,COG0716@2|Bacteria,COG1143@2|Bacteria,1TRYM@1239|Firmicutes,247NM@186801|Clostridia,25SY8@186804|Peptostreptococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Flavodoxin_3,Flavodoxin_5
PNCOCPKN_00962	511680.BUTYVIB_01308	0.0	1019.0	COG1961@1|root,COG1961@2|Bacteria,1TSXI@1239|Firmicutes,248RE@186801|Clostridia,4C0RY@830|Butyrivibrio	186801|Clostridia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
PNCOCPKN_00963	511680.BUTYVIB_01309	0.0	1047.0	COG1961@1|root,COG1961@2|Bacteria,1TQJB@1239|Firmicutes,248GP@186801|Clostridia,4C1ME@830|Butyrivibrio	186801|Clostridia	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
PNCOCPKN_00964	511680.BUTYVIB_01310	0.0	1062.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,4BZ91@830|Butyrivibrio	186801|Clostridia	L	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
PNCOCPKN_00965	483218.BACPEC_02524	4.5e-50	159.0	2EMSU@1|root,33FF8@2|Bacteria,1VNSY@1239|Firmicutes,24VV8@186801|Clostridia,26CD4@186813|unclassified Clostridiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00966	483218.BACPEC_02525	4.38e-88	259.0	COG2337@1|root,COG2337@2|Bacteria,1V2KH@1239|Firmicutes,24GDW@186801|Clostridia,26BTN@186813|unclassified Clostridiales	186801|Clostridia	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PemK_toxin
PNCOCPKN_00968	511680.BUTYVIB_01314	1.47e-66	202.0	2CF7Q@1|root,33XS3@2|Bacteria,1VVM3@1239|Firmicutes,2515J@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00969	622312.ROSEINA2194_03549	1.1e-92	271.0	28KMZ@1|root,2ZA6B@2|Bacteria,1UYQS@1239|Firmicutes,24CNQ@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00970	511680.BUTYVIB_01318	1.64e-68	207.0	COG1396@1|root,COG1396@2|Bacteria,1V44K@1239|Firmicutes,24IS6@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
PNCOCPKN_00971	483218.BACPEC_02530	1.73e-42	140.0	COG3655@1|root,COG3655@2|Bacteria,1VGUT@1239|Firmicutes,24S9V@186801|Clostridia,26C8P@186813|unclassified Clostridiales	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
PNCOCPKN_00972	483218.BACPEC_02531	1.06e-48	155.0	2BZU2@1|root,32R5R@2|Bacteria,1V6T6@1239|Firmicutes,24M8C@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00973	483218.BACPEC_02532	3.6e-73	219.0	COG3620@1|root,COG3620@2|Bacteria,1V561@1239|Firmicutes,24HSY@186801|Clostridia,26C53@186813|unclassified Clostridiales	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PNCOCPKN_00974	483218.BACPEC_02533	5.72e-118	340.0	28ITQ@1|root,2Z8SM@2|Bacteria,1UZFX@1239|Firmicutes,24F7S@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00975	511680.BUTYVIB_01323	6.68e-52	164.0	2CBWZ@1|root,32X4Z@2|Bacteria,1VA6P@1239|Firmicutes,24NPT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00976	511680.BUTYVIB_01325	8.07e-164	459.0	2BZFJ@1|root,2ZBED@2|Bacteria,1UYKC@1239|Firmicutes,24DGE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00977	483218.BACPEC_02537	1.33e-120	345.0	2CF7R@1|root,2Z8FG@2|Bacteria,1UZ4N@1239|Firmicutes,24F0T@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00978	483218.BACPEC_02538	2.32e-121	346.0	28MQP@1|root,2ZAZH@2|Bacteria,1UBV0@1239|Firmicutes,24EH8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00979	511680.BUTYVIB_01328	4.67e-116	332.0	2EETS@1|root,338M9@2|Bacteria,1VH0G@1239|Firmicutes,24RA3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00980	483218.BACPEC_02541	1.26e-28	102.0	2DPR9@1|root,33327@2|Bacteria,1VJE9@1239|Firmicutes,24QUD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00981	483218.BACPEC_02542	7.81e-106	308.0	2DBPR@1|root,2ZAAE@2|Bacteria,1UHKH@1239|Firmicutes,25E1R@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	AgrB
PNCOCPKN_00982	511680.BUTYVIB_01332	8.77e-299	816.0	COG3290@1|root,COG3290@2|Bacteria,1TPZT@1239|Firmicutes,2494S@186801|Clostridia,4BXK3@830|Butyrivibrio	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,SPOB_a
PNCOCPKN_00983	511680.BUTYVIB_01333	9.06e-182	505.0	COG3279@1|root,COG3279@2|Bacteria,1UYHU@1239|Firmicutes,24CBK@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
PNCOCPKN_00984	483218.BACPEC_02546	1.16e-128	366.0	COG4512@1|root,COG4512@2|Bacteria,1VJAH@1239|Firmicutes,25BJD@186801|Clostridia	186801|Clostridia	KOT	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07813	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	AgrB
PNCOCPKN_00985	483218.BACPEC_02547	3.81e-32	111.0	2EKDM@1|root,33E3X@2|Bacteria,1VP6P@1239|Firmicutes,24WGH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00986	511680.BUTYVIB_01336	3.7e-297	812.0	COG3290@1|root,COG3290@2|Bacteria,1V46S@1239|Firmicutes,24KBY@186801|Clostridia,4BXJC@830|Butyrivibrio	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
PNCOCPKN_00987	511680.BUTYVIB_01337	2.91e-165	462.0	COG3279@1|root,COG3279@2|Bacteria,1VBY3@1239|Firmicutes,24GY2@186801|Clostridia,4BXJR@830|Butyrivibrio	186801|Clostridia	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
PNCOCPKN_00988	511680.BUTYVIB_01338	2.07e-68	207.0	COG1396@1|root,COG1396@2|Bacteria,1V9SP@1239|Firmicutes,24MFU@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19
PNCOCPKN_00989	511680.BUTYVIB_01339	7.17e-109	313.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia,4BWE2@830|Butyrivibrio	186801|Clostridia	G	MGS-like domain	mgsA	-	2.7.1.24,4.2.3.3	ko:K00859,ko:K01734	ko00640,ko00770,ko01100,ko01120,map00640,map00770,map01100,map01120	M00120	R00130,R01016	RC00002,RC00078,RC00424	ko00000,ko00001,ko00002,ko01000	-	-	-	MGS
PNCOCPKN_00990	511680.BUTYVIB_01340	2.33e-199	551.0	COG2207@1|root,COG2207@2|Bacteria,1TXIY@1239|Firmicutes,248D1@186801|Clostridia,4BZ7M@830|Butyrivibrio	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
PNCOCPKN_00991	511680.BUTYVIB_01341	1.15e-237	652.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,4BXTZ@830|Butyrivibrio	186801|Clostridia	G	Beta galactosidase small chain	cbgA	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
PNCOCPKN_00992	511680.BUTYVIB_01342	0.0	1314.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,4BXTZ@830|Butyrivibrio	186801|Clostridia	G	Beta galactosidase small chain	cbgA	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
PNCOCPKN_00993	511680.BUTYVIB_01343	1.47e-198	558.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,4C1ND@830|Butyrivibrio	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
PNCOCPKN_00994	511680.BUTYVIB_01351	4.3e-96	280.0	2DBQB@1|root,2ZAD7@2|Bacteria,1UZKJ@1239|Firmicutes,24EM7@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
PNCOCPKN_00995	483218.BACPEC_02556	2.71e-260	714.0	2CKMK@1|root,32SCM@2|Bacteria,1VSC3@1239|Firmicutes,24XNS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_00996	483218.BACPEC_02557	1.53e-115	332.0	COG1595@1|root,COG1595@2|Bacteria,1V7ME@1239|Firmicutes,24GHU@186801|Clostridia,269XK@186813|unclassified Clostridiales	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
PNCOCPKN_00997	511680.BUTYVIB_01354	2.15e-215	595.0	2A5XA@1|root,30UPB@2|Bacteria,1VZN9@1239|Firmicutes,2587U@186801|Clostridia,4BXYI@830|Butyrivibrio	186801|Clostridia	S	Domain of unknown function (DUF4367)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4367
PNCOCPKN_00998	511680.BUTYVIB_01355	7e-148	416.0	28P9U@1|root,2ZC37@2|Bacteria,1V32C@1239|Firmicutes,24FS7@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
PNCOCPKN_00999	483218.BACPEC_02563	3e-88	260.0	2EHP2@1|root,33BEV@2|Bacteria,1VP9P@1239|Firmicutes,24UZ4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01000	483218.BACPEC_02564	6.91e-118	337.0	2EWWD@1|root,33Q7S@2|Bacteria,1VR49@1239|Firmicutes,24YI6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01001	483218.BACPEC_02565	6.64e-74	221.0	2CF7T@1|root,33VII@2|Bacteria,1VUEE@1239|Firmicutes,250K4@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01002	483218.BACPEC_02566	4.23e-45	145.0	2DRY9@1|root,33DNC@2|Bacteria,1V1G6@1239|Firmicutes,24GGT@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01003	483218.BACPEC_02567	1.11e-27	100.0	2DYCK@1|root,3495D@2|Bacteria,1VYPH@1239|Firmicutes,253MW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01004	483218.BACPEC_02568	1.51e-60	187.0	2ATI9@1|root,31J23@2|Bacteria,1V7YH@1239|Firmicutes,24JQS@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01005	483218.BACPEC_02569	0.0	953.0	COG0840@1|root,COG3850@1|root,COG0840@2|Bacteria,COG3850@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,268D0@186813|unclassified Clostridiales	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
PNCOCPKN_01006	1235793.C809_03029	2.1e-156	443.0	COG2801@1|root,COG2801@2|Bacteria,1TPEH@1239|Firmicutes,24DNX@186801|Clostridia,27T8M@186928|unclassified Lachnospiraceae	186801|Clostridia	L	DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
PNCOCPKN_01007	397290.C810_02903	8.12e-44	144.0	COG2963@1|root,COG2963@2|Bacteria,1V9ZX@1239|Firmicutes,24P3X@186801|Clostridia,27RZY@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
PNCOCPKN_01008	622312.ROSEINA2194_04423	4.13e-19	82.8	COG1309@1|root,COG1309@2|Bacteria,1U1ZX@1239|Firmicutes,24ERU@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
PNCOCPKN_01009	622312.ROSEINA2194_00711	7.22e-262	719.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia	186801|Clostridia	C	alcohol dehydrogenase	fucO	-	1.1.1.77	ko:K00048	ko00630,ko00640,ko01120,map00630,map00640,map01120	-	R01781,R02257	RC00087,RC00099	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
PNCOCPKN_01010	622312.ROSEINA2194_03091	0.0	899.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
PNCOCPKN_01011	585394.RHOM_05195	0.0	893.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
PNCOCPKN_01012	585394.RHOM_05190	2.44e-190	531.0	COG0152@1|root,COG0152@2|Bacteria	2|Bacteria	F	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6,6.3.4.13	ko:K01923,ko:K01945,ko:K03566	ko00230,ko01100,ko01110,ko01130,ko02026,map00230,map01100,map01110,map01130,map02026	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	SAICAR_synt
PNCOCPKN_01013	585394.RHOM_05185	0.0	954.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
PNCOCPKN_01015	585394.RHOM_05175	2.9e-172	481.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS19265	TIM
PNCOCPKN_01016	585394.RHOM_05170	1.12e-269	741.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia	186801|Clostridia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
PNCOCPKN_01017	585394.RHOM_05165	7.22e-238	654.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia	186801|Clostridia	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
PNCOCPKN_01018	585394.RHOM_05155	1.19e-155	441.0	COG1387@1|root,COG1387@2|Bacteria,1TRKS@1239|Firmicutes,249TM@186801|Clostridia	186801|Clostridia	E	Histidinol phosphate phosphatase, HisJ family	hisK	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
PNCOCPKN_01019	1304866.K413DRAFT_4421	3.4e-121	361.0	28IAA@1|root,2Z8CW@2|Bacteria,1TQHP@1239|Firmicutes,248TG@186801|Clostridia,36F51@31979|Clostridiaceae	186801|Clostridia	S	DHHW protein	-	-	-	-	-	-	-	-	-	-	-	-	DHHW
PNCOCPKN_01020	428125.CLOLEP_02050	4.28e-196	559.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,3WH3T@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
PNCOCPKN_01021	1519439.JPJG01000008_gene1174	1.25e-68	214.0	2CBD1@1|root,32SNG@2|Bacteria,1VAVB@1239|Firmicutes,24Q8B@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01022	478749.BRYFOR_05725	2.66e-40	148.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
PNCOCPKN_01023	1410633.JHWR01000003_gene733	4.58e-31	134.0	COG1595@1|root,COG1595@2|Bacteria,1V8Z0@1239|Firmicutes,24KTC@186801|Clostridia,27MRQ@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2,WG_beta_rep,zinc_ribbon_2
PNCOCPKN_01026	585394.RHOM_05145	0.0	2251.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia	186801|Clostridia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
PNCOCPKN_01027	622312.ROSEINA2194_01402	8.35e-199	552.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia	186801|Clostridia	K	lysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PNCOCPKN_01028	585394.RHOM_05135	0.0	1207.0	COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,248ZI@186801|Clostridia	186801|Clostridia	L	helicase	dinG	-	3.1.12.1,3.6.4.12	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	-	-	-	DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1
PNCOCPKN_01029	622312.ROSEINA2194_00293	9.74e-38	127.0	COG1925@1|root,COG1925@2|Bacteria,1VEJ5@1239|Firmicutes,24R2F@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
PNCOCPKN_01030	585394.RHOM_04815	1.41e-109	337.0	COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG4991@2|Bacteria,1TRKG@1239|Firmicutes,249Y4@186801|Clostridia	186801|Clostridia	MT	NlpC p60 family protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3
PNCOCPKN_01031	1121115.AXVN01000030_gene3609	0.0	897.0	COG2407@1|root,COG2407@2|Bacteria,1TQDX@1239|Firmicutes,247N8@186801|Clostridia,3XZ0K@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Fucose_iso_C
PNCOCPKN_01032	658086.HMPREF0994_00224	1.25e-99	294.0	28PTU@1|root,2ZCEZ@2|Bacteria,1U95M@1239|Firmicutes,247W6@186801|Clostridia,27M68@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4867
PNCOCPKN_01033	1226325.HMPREF1548_06302	4.43e-290	799.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,36F3K@31979|Clostridiaceae	186801|Clostridia	G	Carbohydrate kinase, FGGY	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
PNCOCPKN_01034	626523.GCWU000342_02293	1.14e-131	386.0	COG1609@1|root,COG1609@2|Bacteria,1TSRM@1239|Firmicutes,24BFS@186801|Clostridia	186801|Clostridia	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_4
PNCOCPKN_01035	397290.C810_04867	5.96e-33	121.0	2B1N9@1|root,31U3S@2|Bacteria,1USHS@1239|Firmicutes,25AHW@186801|Clostridia,27QGU@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01037	585394.RHOM_11330	6.35e-98	285.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia	186801|Clostridia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
PNCOCPKN_01038	622312.ROSEINA2194_00724	0.0	1217.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia	186801|Clostridia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
PNCOCPKN_01039	622312.ROSEINA2194_00725	2.58e-32	114.0	COG1314@1|root,COG1314@2|Bacteria,1VG46@1239|Firmicutes	1239|Firmicutes	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
PNCOCPKN_01040	622312.ROSEINA2194_00739	2.88e-247	688.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
PNCOCPKN_01041	585394.RHOM_12670	8.64e-130	414.0	COG0642@1|root,COG0642@2|Bacteria,1UYZX@1239|Firmicutes,25E9T@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2,HATPase_c,HisKA,PAS_3,Response_reg,SnoaL_3
PNCOCPKN_01042	585394.RHOM_11360	1.6e-122	359.0	COG2755@1|root,COG2755@2|Bacteria,1V2MD@1239|Firmicutes,24FWG@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
PNCOCPKN_01043	622312.ROSEINA2194_02856	4.51e-228	639.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia	186801|Clostridia	M	Membrane protein involved in D-alanine export	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
PNCOCPKN_01044	585394.RHOM_11370	4.99e-174	501.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
PNCOCPKN_01045	585394.RHOM_11375	2.15e-164	464.0	COG1307@1|root,COG1307@2|Bacteria,1TSKD@1239|Firmicutes,24AE9@186801|Clostridia	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
PNCOCPKN_01046	622312.ROSEINA2194_02860	1.55e-126	378.0	COG5279@1|root,COG5279@2|Bacteria,1TY2Q@1239|Firmicutes,24BDS@186801|Clostridia	186801|Clostridia	D	protein involved in cytokinesis, contains TGc (transglutaminase protease-like) domain	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
PNCOCPKN_01047	585394.RHOM_11380	4.37e-235	655.0	COG1362@1|root,COG1362@2|Bacteria,1TQ3Z@1239|Firmicutes,248UP@186801|Clostridia	186801|Clostridia	E	M18 family aminopeptidase	-	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
PNCOCPKN_01048	585394.RHOM_11385	5.98e-77	233.0	2C2B5@1|root,32RA4@2|Bacteria,1V6P1@1239|Firmicutes,24N51@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01049	622312.ROSEINA2194_02871	4.53e-41	135.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia	186801|Clostridia	K	Cold shock protein	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
PNCOCPKN_01050	622312.ROSEINA2194_02884	1.12e-95	282.0	COG4720@1|root,COG4720@2|Bacteria,1V1E7@1239|Firmicutes,25CJR@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
PNCOCPKN_01051	622312.ROSEINA2194_02885	5.63e-204	572.0	COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,24919@186801|Clostridia	186801|Clostridia	E	Aminotransferase	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
PNCOCPKN_01052	397287.C807_00219	1.88e-83	254.0	COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,249FE@186801|Clostridia,27U4Q@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Region found in RelA / SpoT proteins	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT,Response_reg
PNCOCPKN_01053	585394.RHOM_11560	4.56e-238	670.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
PNCOCPKN_01054	585394.RHOM_11415	1.03e-115	352.0	COG0840@1|root,COG0840@2|Bacteria,1TQW8@1239|Firmicutes,24EE8@186801|Clostridia	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal
PNCOCPKN_01055	556261.HMPREF0240_00860	1.62e-151	453.0	COG2199@1|root,COG2199@2|Bacteria,1TQKY@1239|Firmicutes,25EP8@186801|Clostridia,36V2W@31979|Clostridiaceae	186801|Clostridia	T	Pfam:Cache_1	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP,dCache_1
PNCOCPKN_01056	622312.ROSEINA2194_02159	4.96e-99	295.0	COG2186@1|root,COG2186@2|Bacteria,1V1Y0@1239|Firmicutes,249UW@186801|Clostridia	186801|Clostridia	K	FCD domain	pdhR	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
PNCOCPKN_01057	585394.RHOM_04720	0.0	941.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PNCOCPKN_01058	622312.ROSEINA2194_02642	0.0	892.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia	186801|Clostridia	V	Abc transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PNCOCPKN_01059	585394.RHOM_04710	6.85e-157	446.0	COG2035@1|root,COG2035@2|Bacteria,1UYD5@1239|Firmicutes,24B08@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
PNCOCPKN_01060	585394.RHOM_04700	1.7e-186	534.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia	186801|Clostridia	E	amino acid carrier protein	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
PNCOCPKN_01061	411462.DORLON_00099	1.45e-201	564.0	2C2TA@1|root,2Z7T7@2|Bacteria,1TS53@1239|Firmicutes,248BA@186801|Clostridia,27WMG@189330|Dorea	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
PNCOCPKN_01062	1410632.JHWW01000013_gene237	8.08e-13	68.9	COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,247VM@186801|Clostridia,27NJZ@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
PNCOCPKN_01063	411474.COPEUT_00629	5.08e-23	99.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	cysA	-	3.6.3.25	ko:K02045,ko:K02052	ko00920,ko02010,ko02024,map00920,map02010,map02024	M00185,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_2
PNCOCPKN_01064	411459.RUMOBE_02708	3.18e-94	287.0	COG1609@1|root,COG1609@2|Bacteria,1UK1H@1239|Firmicutes,249XN@186801|Clostridia,3XZFY@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
PNCOCPKN_01065	140626.JHWB01000022_gene2045	1.42e-105	312.0	COG0406@1|root,COG0406@2|Bacteria,1U7UE@1239|Firmicutes,24F5B@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
PNCOCPKN_01067	1408306.JHXX01000003_gene1412	9.87e-74	224.0	COG0454@1|root,COG0456@2|Bacteria,1VAJN@1239|Firmicutes,24H93@186801|Clostridia,4BXFH@830|Butyrivibrio	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
PNCOCPKN_01068	1414720.CBYM010000020_gene2482	1.62e-179	518.0	COG0657@1|root,COG0657@2|Bacteria,1USHI@1239|Firmicutes,24DIN@186801|Clostridia,36IKW@31979|Clostridiaceae	186801|Clostridia	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01069	1280680.AUJU01000023_gene2540	3.64e-114	349.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,4C1ND@830|Butyrivibrio	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
PNCOCPKN_01070	1410616.JHXE01000014_gene390	2.68e-139	402.0	COG0583@1|root,COG0583@2|Bacteria,1TQ6Y@1239|Firmicutes,24KGS@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PNCOCPKN_01071	742738.HMPREF9460_00250	6.22e-14	70.1	arCOG04966@1|root,33EHA@2|Bacteria,1VN4X@1239|Firmicutes,24VEA@186801|Clostridia,26C56@186813|unclassified Clostridiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01072	742733.HMPREF9469_01638	2.67e-63	200.0	COG0163@1|root,COG0163@2|Bacteria,1V3JV@1239|Firmicutes,24HE5@186801|Clostridia,220IG@1506553|Lachnoclostridium	186801|Clostridia	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
PNCOCPKN_01073	445973.CLOBAR_00478	2.06e-268	744.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,25RRQ@186804|Peptostreptococcaceae	186801|Clostridia	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
PNCOCPKN_01074	1235790.C805_00783	2.65e-116	341.0	COG0395@1|root,COG0395@2|Bacteria,1TSGI@1239|Firmicutes,24BDH@186801|Clostridia,25VTP@186806|Eubacteriaceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10190	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	BPD_transp_1
PNCOCPKN_01075	1469948.JPNB01000002_gene2491	8.25e-137	395.0	COG1175@1|root,COG1175@2|Bacteria,1TPMR@1239|Firmicutes,2494U@186801|Clostridia,36EUX@31979|Clostridiaceae	186801|Clostridia	P	PFAM Binding-protein-dependent transport	-	-	-	ko:K02025,ko:K10189,ko:K10241	ko02010,map02010	M00199,M00206,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.23,3.A.1.1.4	-	-	BPD_transp_1
PNCOCPKN_01076	1163671.JAGI01000002_gene2752	7.05e-150	441.0	COG1653@1|root,COG1653@2|Bacteria,1TQ0V@1239|Firmicutes,2481M@186801|Clostridia,36E6U@31979|Clostridiaceae	186801|Clostridia	G	Extracellular solute-binding protein	lacE	-	-	ko:K02027,ko:K10188	ko02010,map02010	M00199,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.4	-	-	SBP_bac_1,SBP_bac_8
PNCOCPKN_01077	500632.CLONEX_00407	3.08e-111	340.0	COG1653@1|root,COG1653@2|Bacteria,1TQ0V@1239|Firmicutes,2481M@186801|Clostridia	186801|Clostridia	G	solute-binding protein	lacE	-	-	ko:K10188	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	SBP_bac_1,SBP_bac_8
PNCOCPKN_01078	180332.JTGN01000015_gene1128	7.99e-196	569.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,248RT@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
PNCOCPKN_01079	180332.JTGN01000015_gene1129	1.89e-131	397.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSN6@1239|Firmicutes,24D7T@186801|Clostridia	186801|Clostridia	T	response regulator	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
PNCOCPKN_01080	574375.BAGA_15745	5.4e-164	463.0	2E47H@1|root,32Z3D@2|Bacteria,1VWJ7@1239|Firmicutes,4HZSQ@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01081	511680.BUTYVIB_01768	2.09e-175	496.0	COG1502@1|root,COG1502@2|Bacteria,1TRJE@1239|Firmicutes,248ZE@186801|Clostridia,4BYQD@830|Butyrivibrio	186801|Clostridia	I	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
PNCOCPKN_01082	622312.ROSEINA2194_00596	1.58e-73	221.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26,HTH_3,HTH_31
PNCOCPKN_01084	742765.HMPREF9457_03768	4.89e-151	428.0	COG1484@1|root,COG1484@2|Bacteria,1TQBX@1239|Firmicutes,249T2@186801|Clostridia,27WZ8@189330|Dorea	186801|Clostridia	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
PNCOCPKN_01085	411468.CLOSCI_00238	3.43e-225	639.0	COG4584@1|root,COG4584@2|Bacteria,1TNY9@1239|Firmicutes,24B59@186801|Clostridia,223J5@1506553|Lachnoclostridium	186801|Clostridia	L	COG COG4584 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	rve
PNCOCPKN_01086	585394.RHOM_04910	0.0	1224.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
PNCOCPKN_01087	585394.RHOM_04905	2.35e-190	547.0	COG0116@1|root,COG0116@2|Bacteria,1TT5F@1239|Firmicutes,249VY@186801|Clostridia	186801|Clostridia	L	Putative RNA methylase family UPF0020	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,UPF0020
PNCOCPKN_01088	585394.RHOM_04900	7.99e-105	309.0	COG5632@1|root,COG5632@2|Bacteria,1V3JT@1239|Firmicutes,24D7K@186801|Clostridia	186801|Clostridia	M	n-acetylmuramoyl-l-alanine amidase	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2
PNCOCPKN_01090	585394.RHOM_04880	1.21e-114	346.0	COG0727@1|root,COG0727@2|Bacteria,1TSB6@1239|Firmicutes,24AQ9@186801|Clostridia	186801|Clostridia	S	N-methylation of lysine residues in flagellin K00599	-	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	CxxCxxCC
PNCOCPKN_01092	622312.ROSEINA2194_02626	1.73e-85	255.0	COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,24HIJ@186801|Clostridia	186801|Clostridia	O	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	nrdG	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
PNCOCPKN_01093	585394.RHOM_06010	6.47e-198	556.0	COG1609@1|root,COG1609@2|Bacteria,1TP9Q@1239|Firmicutes,24ARJ@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	araR	-	-	ko:K02103	-	-	-	-	ko00000,ko03000	-	-	-	GntR,Peripla_BP_3
PNCOCPKN_01094	622312.ROSEINA2194_01565	8.5e-97	287.0	COG0328@1|root,COG3341@1|root,COG0328@2|Bacteria,COG3341@2|Bacteria,1V442@1239|Firmicutes,24HSE@186801|Clostridia	186801|Clostridia	L	Ribonuclease HI	rnhA	-	3.1.26.4	ko:K03469,ko:K06993	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,RNase_H
PNCOCPKN_01095	585394.RHOM_06000	7.1e-82	253.0	COG1434@1|root,COG1434@2|Bacteria,1VA42@1239|Firmicutes,24HKK@186801|Clostridia	186801|Clostridia	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
PNCOCPKN_01096	585394.RHOM_05995	3.28e-61	189.0	2F3F9@1|root,33W92@2|Bacteria,1VVFD@1239|Firmicutes,25130@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01097	357809.Cphy_0713	9.01e-137	392.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,21Y17@1506553|Lachnoclostridium	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
PNCOCPKN_01098	1121296.JONJ01000004_gene974	3.73e-50	162.0	COG5496@1|root,COG5496@2|Bacteria,1VAZJ@1239|Firmicutes,24MWR@186801|Clostridia,222ZV@1506553|Lachnoclostridium	186801|Clostridia	S	Thioesterase superfamily	-	-	3.1.2.29	ko:K18700	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
PNCOCPKN_01099	585394.RHOM_04865	0.0	1311.0	COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia	186801|Clostridia	F	Ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
PNCOCPKN_01100	585394.RHOM_04860	5.46e-62	195.0	COG1846@1|root,COG1846@2|Bacteria,1VEYN@1239|Firmicutes,24S21@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
PNCOCPKN_01101	585394.RHOM_04855	0.0	986.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia	186801|Clostridia	V	Abc transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PNCOCPKN_01102	585394.RHOM_04850	0.0	1156.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PNCOCPKN_01103	585394.RHOM_04845	3.53e-63	199.0	COG1418@1|root,COG1418@2|Bacteria,1V4QX@1239|Firmicutes,24JBS@186801|Clostridia	186801|Clostridia	S	HD superfamily hydrolase	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
PNCOCPKN_01104	585394.RHOM_10060	1.4e-314	860.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
PNCOCPKN_01105	622312.ROSEINA2194_00798	5.94e-314	859.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
PNCOCPKN_01106	585394.RHOM_10070	2.74e-129	377.0	COG0721@1|root,COG1670@1|root,COG0721@2|Bacteria,COG1670@2|Bacteria,1V6E0@1239|Firmicutes,24G2M@186801|Clostridia	186801|Clostridia	J	acetyltransferase, GNAT family	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
PNCOCPKN_01107	622312.ROSEINA2194_00796	4.85e-296	810.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,248XN@186801|Clostridia	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12,6.1.1.23	ko:K01876,ko:K09759	ko00970,map00970	M00359,M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_2,tRNA_anti-codon
PNCOCPKN_01108	140626.JHWB01000013_gene770	0.0	1094.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_N,Big_2,CBM_20,CBM_48,Cadherin-like,Malt_amylase_C,PUD,SLH
PNCOCPKN_01109	585394.RHOM_10085	1.49e-88	263.0	COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,24MMZ@186801|Clostridia	186801|Clostridia	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	yfkJ	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
PNCOCPKN_01110	936596.HMPREF1495_1473	1.15e-281	771.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,1HW2I@1164882|Lachnoanaerobaculum	186801|Clostridia	L	DNA binding domain of tn916 integrase	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_integrase
PNCOCPKN_01111	483218.BACPEC_01806	7.88e-42	137.0	2AJW5@1|root,3321D@2|Bacteria,1VFNY@1239|Firmicutes,24RSP@186801|Clostridia,269TA@186813|unclassified Clostridiales	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
PNCOCPKN_01112	483218.BACPEC_01805	3.38e-94	276.0	COG1595@1|root,COG1595@2|Bacteria,1V22M@1239|Firmicutes,24EDG@186801|Clostridia,269K8@186813|unclassified Clostridiales	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4,Sigma70_r4_2
PNCOCPKN_01113	483218.BACPEC_01804	9.14e-75	224.0	COG1396@1|root,COG1396@2|Bacteria,1UKPK@1239|Firmicutes,25G0R@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01114	97139.C824_04607	5.46e-37	128.0	2BPCF@1|root,32I4G@2|Bacteria,1V6FP@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01115	1151292.QEW_2319	2.16e-96	301.0	COG1277@1|root,COG1277@2|Bacteria,1UTUG@1239|Firmicutes,25EAK@186801|Clostridia	186801|Clostridia	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
PNCOCPKN_01116	796942.HMPREF9623_01355	5.83e-128	373.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia	186801|Clostridia	V	Abc transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PNCOCPKN_01117	1536774.H70357_27985	3.1e-109	332.0	COG0642@1|root,COG2205@2|Bacteria,1VS9T@1239|Firmicutes,4IS7H@91061|Bacilli,26UAF@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	-	-	2.7.13.3	ko:K18350	ko01502,ko02020,map01502,map02020	M00652,M00657	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA
PNCOCPKN_01118	1235798.C817_05181	8.99e-109	319.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,27WFK@189330|Dorea	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	ko:K18349	ko01502,ko02020,map01502,map02020	M00652,M00657	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
PNCOCPKN_01119	1235793.C809_00188	2.84e-56	177.0	296J0@1|root,30WDX@2|Bacteria,1UICE@1239|Firmicutes,25EHH@186801|Clostridia,27N3K@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
PNCOCPKN_01120	742741.HMPREF9475_02338	2.32e-243	678.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,2481D@186801|Clostridia,21XR9@1506553|Lachnoclostridium	186801|Clostridia	U	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
PNCOCPKN_01121	1280698.AUJS01000077_gene3309	1.94e-162	459.0	COG4823@1|root,COG4823@2|Bacteria,1V17V@1239|Firmicutes,24E48@186801|Clostridia	186801|Clostridia	V	Abi-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
PNCOCPKN_01123	483218.BACPEC_01795	0.0	1771.0	COG1669@1|root,COG4227@1|root,COG1669@2|Bacteria,COG4227@2|Bacteria,1TQN4@1239|Firmicutes,2482H@186801|Clostridia,268CY@186813|unclassified Clostridiales	186801|Clostridia	L	Domain of unknown function (DUF4316)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3849,DUF4316,Peptidase_M78,YodL,zf-CHC2
PNCOCPKN_01124	483218.BACPEC_01794	2.24e-74	223.0	COG0745@1|root,COG0745@2|Bacteria,1V65U@1239|Firmicutes,24HUB@186801|Clostridia,2693F@186813|unclassified Clostridiales	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
PNCOCPKN_01125	483218.BACPEC_01793	9.8e-158	442.0	2DBMJ@1|root,2Z9Z8@2|Bacteria,1UTJA@1239|Firmicutes,24EBB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01126	483218.BACPEC_01792	1.9e-116	337.0	28JQQ@1|root,2Z9GH@2|Bacteria,1UZ31@1239|Firmicutes,24EXK@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01127	622312.ROSEINA2194_03345	1.29e-132	378.0	2C0GJ@1|root,2Z7PN@2|Bacteria,1V0HT@1239|Firmicutes,24FCI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01128	622312.ROSEINA2194_03345	1.8e-16	75.9	2C0GJ@1|root,2Z7PN@2|Bacteria,1V0HT@1239|Firmicutes,24FCI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01129	483218.BACPEC_01789	6.79e-79	234.0	28P4A@1|root,2ZBZJ@2|Bacteria,1V39Y@1239|Firmicutes,24GP0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01130	483218.BACPEC_01788	2.55e-234	644.0	28JMS@1|root,2Z9E9@2|Bacteria,1UZBX@1239|Firmicutes,24D7A@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01131	483218.BACPEC_01786	3.6e-184	533.0	COG0553@1|root,COG0553@2|Bacteria,1TPQA@1239|Firmicutes,2491X@186801|Clostridia,268CK@186813|unclassified Clostridiales	186801|Clostridia	L	helicase C-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3849,Helicase_C,ResIII,SNF2_N
PNCOCPKN_01132	411461.DORFOR_03181	0.0	1232.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,27VY5@189330|Dorea	186801|Clostridia	L	Domain of unknown function (DUF4368)	tnpX	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
PNCOCPKN_01133	1214217.ALNF01000037_gene364	1.3e-36	123.0	2AH2U@1|root,32XD3@2|Bacteria,1VBGJ@1239|Firmicutes,4IJBK@91061|Bacilli,1WU2F@1307|Streptococcus suis	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01134	1214217.ALNF01000037_gene365	1.99e-48	154.0	COG4443@1|root,COG4443@2|Bacteria,1VEFE@1239|Firmicutes,4HNSP@91061|Bacilli,1WU1I@1307|Streptococcus suis	91061|Bacilli	S	Transcriptional Coactivator p15 (PC4)	XK26_06125	-	-	-	-	-	-	-	-	-	-	-	PC4
PNCOCPKN_01135	1214217.ALNF01000037_gene366	1.13e-191	533.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,4IJ2M@91061|Bacilli,1WTIK@1307|Streptococcus suis	91061|Bacilli	K	ParB-like nuclease domain	parB_1	-	-	-	-	-	-	-	-	-	-	-	ParBc
PNCOCPKN_01136	1214217.ALNF01000037_gene367	1.82e-227	627.0	COG1196@1|root,COG1196@2|Bacteria,1TRNI@1239|Firmicutes,4HHXH@91061|Bacilli,1WTYA@1307|Streptococcus suis	91061|Bacilli	D	Plasmid recombination enzyme	XK26_06135	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
PNCOCPKN_01137	411461.DORFOR_03187	2.77e-249	684.0	COG0468@1|root,COG0468@2|Bacteria,1V9SB@1239|Firmicutes,25E2S@186801|Clostridia,27V7W@189330|Dorea	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25
PNCOCPKN_01138	1154860.SAG0136_11680	1.44e-104	302.0	COG1595@1|root,COG1595@2|Bacteria,1TRPH@1239|Firmicutes	1239|Firmicutes	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
PNCOCPKN_01139	1214217.ALNF01000037_gene371	1.02e-94	276.0	COG1595@1|root,COG1595@2|Bacteria,1UUN2@1239|Firmicutes,4IJ8C@91061|Bacilli,1WTWZ@1307|Streptococcus suis	91061|Bacilli	K	DNA-templated transcription, initiation	XK26_06150	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01140	1123314.AUIO01000002_gene1891	1.81e-114	328.0	COG1191@1|root,COG1191@2|Bacteria,1V1GF@1239|Firmicutes	1239|Firmicutes	K	Psort location Cytoplasmic, score	XK26_06155	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4
PNCOCPKN_01141	658088.HMPREF0987_02718	1.38e-155	437.0	COG2963@1|root,COG2963@2|Bacteria,1V4FD@1239|Firmicutes,24GUY@186801|Clostridia,27NJX@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_Tnp_1
PNCOCPKN_01142	742765.HMPREF9457_02411	1.85e-201	557.0	COG2801@1|root,COG2801@2|Bacteria,1TQEG@1239|Firmicutes,25B5A@186801|Clostridia,27WHD@189330|Dorea	186801|Clostridia	L	COG COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,HTH_28,rve,rve_2
PNCOCPKN_01143	1000569.HMPREF1040_0244	0.0	1265.0	COG0480@1|root,COG0480@2|Bacteria,1TPQH@1239|Firmicutes,4H3U6@909932|Negativicutes	909932|Negativicutes	J	elongation factor	-	-	-	ko:K18220	-	-	-	-	br01600,ko00000,ko01504	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
PNCOCPKN_01144	1121864.OMO_01641	4.2e-79	235.0	2C5R4@1|root,2ZC1N@2|Bacteria,1V292@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
PNCOCPKN_01145	585394.RHOM_15365	0.0	3128.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,1TPQA@1239|Firmicutes,2491X@186801|Clostridia	186801|Clostridia	L	helicase C-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3849,Helicase_C,ResIII,SNF2_N
PNCOCPKN_01146	483218.BACPEC_01783	1.31e-54	171.0	2DP25@1|root,3307U@2|Bacteria,1VFQB@1239|Firmicutes,24RCV@186801|Clostridia,269UA@186813|unclassified Clostridiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01147	411467.BACCAP_02982	9.42e-108	309.0	COG3631@1|root,COG3631@2|Bacteria,1V76Z@1239|Firmicutes,24MNK@186801|Clostridia,2692T@186813|unclassified Clostridiales	186801|Clostridia	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
PNCOCPKN_01148	511680.BUTYVIB_00633	2.26e-22	89.4	2F6CB@1|root,33YVQ@2|Bacteria,1VWV0@1239|Firmicutes,2523Z@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01149	585394.RHOM_15375	0.0	1084.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	-	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	DUF3945,Topoisom_bac,Toprim,Toprim_Crpt
PNCOCPKN_01150	1235799.C818_03909	9.1e-190	551.0	COG2433@1|root,COG2433@2|Bacteria,1V0VN@1239|Firmicutes,24ABK@186801|Clostridia,27MDE@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4366)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4366
PNCOCPKN_01151	585394.RHOM_15385	5.47e-18	78.6	2F6I0@1|root,33Z10@2|Bacteria,1VWYS@1239|Firmicutes,24PWX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01152	742741.HMPREF9475_02326	1.56e-283	816.0	COG0739@1|root,COG0791@1|root,COG0739@2|Bacteria,COG0791@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia,21YV3@1506553|Lachnoclostridium	186801|Clostridia	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,Peptidase_M23
PNCOCPKN_01153	585394.RHOM_15395	0.0	1396.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,24BXM@186801|Clostridia	186801|Clostridia	U	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87
PNCOCPKN_01154	97139.C824_04439	1.33e-69	212.0	COG3451@1|root,COG3451@2|Bacteria,1V74G@1239|Firmicutes,24GFI@186801|Clostridia,36KCQ@31979|Clostridiaceae	186801|Clostridia	U	PrgI family protein	-	-	-	-	-	-	-	-	-	-	-	-	PrgI
PNCOCPKN_01155	97139.C824_04440	3.02e-167	472.0	28HUM@1|root,2Z81B@2|Bacteria,1TNZ2@1239|Firmicutes,248SU@186801|Clostridia,36EXM@31979|Clostridiaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01156	471875.RUMLAC_00006	0.000235	44.7	COG3077@1|root,COG3077@2|Bacteria,1VGJW@1239|Firmicutes,24JNU@186801|Clostridia,3WM3W@541000|Ruminococcaceae	186801|Clostridia	L	Addiction module antitoxin, RelB DinJ family	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
PNCOCPKN_01157	1280676.AUJO01000005_gene421	8.17e-111	334.0	COG2382@1|root,COG2382@2|Bacteria,1V888@1239|Firmicutes,24CN5@186801|Clostridia,4C1R1@830|Butyrivibrio	186801|Clostridia	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Barstar,CBM_6,Dockerin_1,Esterase
PNCOCPKN_01158	1185876.BN8_06021	2.33e-47	177.0	COG5434@1|root,COG5434@2|Bacteria,4NID5@976|Bacteroidetes,47S55@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28
PNCOCPKN_01159	1235798.C817_01831	0.0	923.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia	186801|Clostridia	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
PNCOCPKN_01160	1235798.C817_01830	6.94e-214	595.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,24XW6@186801|Clostridia,27WMD@189330|Dorea	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
PNCOCPKN_01161	97139.C824_03911	6.56e-186	520.0	COG1082@1|root,COG1082@2|Bacteria,1TPJT@1239|Firmicutes,24A6G@186801|Clostridia,36G1X@31979|Clostridiaceae	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
PNCOCPKN_01162	1235798.C817_01828	4.21e-189	527.0	COG1082@1|root,COG1082@2|Bacteria,1TPJT@1239|Firmicutes,24A6G@186801|Clostridia	186801|Clostridia	G	TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
PNCOCPKN_01163	1235798.C817_01827	3.68e-184	520.0	COG0673@1|root,COG0673@2|Bacteria,1TQFW@1239|Firmicutes,24BIG@186801|Clostridia,27WKS@189330|Dorea	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
PNCOCPKN_01164	1235798.C817_01826	4.26e-312	862.0	COG1653@1|root,COG1653@2|Bacteria,1TSF4@1239|Firmicutes,24DIH@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
PNCOCPKN_01165	1235798.C817_01825	2.25e-187	523.0	COG0395@1|root,COG0395@2|Bacteria,1TPHS@1239|Firmicutes,24AJG@186801|Clostridia	186801|Clostridia	G	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K17320	ko02010,map02010	M00207,M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
PNCOCPKN_01166	1235798.C817_01824	1.42e-191	534.0	COG4209@1|root,COG4209@2|Bacteria,1TP33@1239|Firmicutes,247UA@186801|Clostridia	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
PNCOCPKN_01167	1235798.C817_01823	6.93e-146	421.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1UYK2@1239|Firmicutes,24G6A@186801|Clostridia	186801|Clostridia	KT	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
PNCOCPKN_01168	1235798.C817_01822	5.98e-254	716.0	COG2972@1|root,COG2972@2|Bacteria,1TS69@1239|Firmicutes,24GEH@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
PNCOCPKN_01172	861450.HMPREF0080_00222	2.47e-20	83.6	COG2265@1|root,COG2265@2|Bacteria,1VGG4@1239|Firmicutes,4H8NV@909932|Negativicutes	909932|Negativicutes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01173	585394.RHOM_13395	4.99e-225	640.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
PNCOCPKN_01174	397288.C806_00845	1.88e-54	172.0	COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,24JJB@186801|Clostridia,27NDR@186928|unclassified Lachnospiraceae	186801|Clostridia	K	HxlR-like helix-turn-helix	hxlR	-	-	-	-	-	-	-	-	-	-	-	HxlR
PNCOCPKN_01175	1235793.C809_01456	6.21e-83	249.0	COG0778@1|root,COG0778@2|Bacteria,1V3YJ@1239|Firmicutes,24BKH@186801|Clostridia,27KJP@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
PNCOCPKN_01176	585394.RHOM_13805	6.32e-274	751.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,247TI@186801|Clostridia	186801|Clostridia	J	SMART PUA domain containing protein	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PUA
PNCOCPKN_01177	585394.RHOM_13815	1.48e-207	579.0	COG0463@1|root,COG0463@2|Bacteria,1TQEM@1239|Firmicutes,249HH@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,TPR_8
PNCOCPKN_01178	585394.RHOM_13820	2.8e-315	859.0	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia	186801|Clostridia	C	PFAM Acetyl-CoA hydrolase transferase	cat	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
PNCOCPKN_01179	622312.ROSEINA2194_02266	5.7e-61	198.0	2DRS1@1|root,33CTC@2|Bacteria,1VPFR@1239|Firmicutes,24X55@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01181	622312.ROSEINA2194_02264	2.88e-174	489.0	COG1131@1|root,COG1131@2|Bacteria,1TS5Y@1239|Firmicutes,24AH1@186801|Clostridia	186801|Clostridia	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PNCOCPKN_01182	622312.ROSEINA2194_02263	1.93e-67	206.0	COG1725@1|root,COG1725@2|Bacteria,1VAC6@1239|Firmicutes,24MVE@186801|Clostridia	186801|Clostridia	K	PFAM Bacterial regulatory proteins, gntR family	-	-	-	-	-	-	-	-	-	-	-	-	GntR
PNCOCPKN_01183	585394.RHOM_13825	4.8e-165	466.0	COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,2480J@186801|Clostridia	186801|Clostridia	E	L-serine dehydratase, iron-sulfur-dependent, alpha subunit	sdaAA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha
PNCOCPKN_01184	585394.RHOM_13830	1.45e-133	381.0	COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,24AEE@186801|Clostridia	186801|Clostridia	E	L-serine dehydratase, iron-sulfur-dependent, beta subunit	sdaAB	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	ACT,SDH_beta
PNCOCPKN_01185	931626.Awo_c29210	1.18e-68	223.0	COG0583@1|root,COG0583@2|Bacteria,1TP6T@1239|Firmicutes,24970@186801|Clostridia,25WDP@186806|Eubacteriaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PNCOCPKN_01186	1042156.CXIVA_05830	5.99e-123	365.0	COG1118@1|root,COG1118@2|Bacteria,1UI1E@1239|Firmicutes,25EAE@186801|Clostridia,36EU6@31979|Clostridiaceae	186801|Clostridia	P	the current gene model (or a revised gene model) may contain a frame shift	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
PNCOCPKN_01187	411468.CLOSCI_02058	1.84e-131	377.0	COG4149@1|root,COG4149@2|Bacteria,1TRNA@1239|Firmicutes,24BR9@186801|Clostridia,21XZN@1506553|Lachnoclostridium	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
PNCOCPKN_01188	1042156.CXIVA_05850	4.16e-126	370.0	COG0725@1|root,COG0725@2|Bacteria,1U9U3@1239|Firmicutes,249VA@186801|Clostridia,36EBM@31979|Clostridiaceae	186801|Clostridia	P	ABC transporter, periplasmic molybdate-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	iHN637.CLJU_RS12820	SBP_bac_11
PNCOCPKN_01189	626939.HMPREF9443_01887	3.41e-86	268.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,4H521@909932|Negativicutes	909932|Negativicutes	O	XdhC and CoxI family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
PNCOCPKN_01190	1256908.HMPREF0373_01761	2.27e-81	243.0	COG2258@1|root,COG2258@2|Bacteria,1V6DS@1239|Firmicutes,24HBA@186801|Clostridia,25X6H@186806|Eubacteriaceae	186801|Clostridia	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
PNCOCPKN_01191	658088.HMPREF0987_01753	4.41e-110	331.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,27IWC@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
PNCOCPKN_01192	411469.EUBHAL_01351	1.35e-195	548.0	COG0303@1|root,COG0303@2|Bacteria,1TP7F@1239|Firmicutes,247TZ@186801|Clostridia,25VS2@186806|Eubacteriaceae	186801|Clostridia	H	Probable molybdopterin binding domain	moeA2	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
PNCOCPKN_01193	657322.FPR_30730	7.54e-127	368.0	COG3608@1|root,COG3608@2|Bacteria,1TRKT@1239|Firmicutes,2492W@186801|Clostridia,3WI66@541000|Ruminococcaceae	186801|Clostridia	S	Selenium-dependent molybdenum hydroxylase system protein, YqeB family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3
PNCOCPKN_01194	1256908.HMPREF0373_00762	3.84e-29	105.0	29XBV@1|root,30J1M@2|Bacteria,1U4VY@1239|Firmicutes,25NV8@186801|Clostridia,25Z8B@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
PNCOCPKN_01195	1235792.C808_01660	3.54e-193	542.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,27JZ4@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
PNCOCPKN_01196	1298920.KI911353_gene785	8.7e-174	496.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,21Z7G@1506553|Lachnoclostridium	186801|Clostridia	E	Cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
PNCOCPKN_01197	1256908.HMPREF0373_01402	7.37e-99	293.0	COG0425@1|root,COG0425@2|Bacteria,1V6BY@1239|Firmicutes,24JW8@186801|Clostridia,25X3M@186806|Eubacteriaceae	186801|Clostridia	O	DsrE/DsrF-like family	yedF	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE,TusA
PNCOCPKN_01198	1298920.KI911353_gene811	2.4e-77	234.0	COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,21Z3U@1506553|Lachnoclostridium	186801|Clostridia	H	Molybdenum cofactor synthesis domain protein	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
PNCOCPKN_01199	1235793.C809_00618	3.31e-69	213.0	COG0315@1|root,COG0315@2|Bacteria,1V3J4@1239|Firmicutes,24H9F@186801|Clostridia,27MYG@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
PNCOCPKN_01200	585394.RHOM_13845	0.0	1168.0	COG1368@1|root,COG1368@2|Bacteria,1TQYQ@1239|Firmicutes,25CNS@186801|Clostridia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
PNCOCPKN_01201	622312.ROSEINA2194_03257	1.56e-31	110.0	298S6@1|root,2ZVWG@2|Bacteria,1W22G@1239|Firmicutes,256U8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01202	742765.HMPREF9457_03575	1.93e-139	394.0	COG2267@1|root,COG2267@2|Bacteria,1TT75@1239|Firmicutes,25FMP@186801|Clostridia	186801|Clostridia	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
PNCOCPKN_01204	411474.COPEUT_01927	9.85e-96	278.0	29B5Y@1|root,2ZY4B@2|Bacteria,1V4IF@1239|Firmicutes,24K82@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01205	511680.BUTYVIB_01764	7.84e-133	377.0	2CZHY@1|root,32T6E@2|Bacteria,1VDM1@1239|Firmicutes,24MKX@186801|Clostridia	186801|Clostridia	S	Putative zincin peptidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3267
PNCOCPKN_01207	1410633.JHWR01000016_gene1040	1.13e-84	252.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,24FRS@186801|Clostridia,27M62@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
PNCOCPKN_01208	1321778.HMPREF1982_03317	1.36e-241	669.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,26AE5@186813|unclassified Clostridiales	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
PNCOCPKN_01209	1341157.RF007C_08915	1.53e-88	266.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,24FVK@186801|Clostridia,3WIGR@541000|Ruminococcaceae	186801|Clostridia	H	riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
PNCOCPKN_01210	1321778.HMPREF1982_03315	2e-158	456.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,26A16@186813|unclassified Clostridiales	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
PNCOCPKN_01211	877424.ATWC01000015_gene635	2.16e-265	769.0	COG0642@1|root,COG0784@1|root,COG1307@1|root,COG0784@2|Bacteria,COG1307@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,27I9U@186928|unclassified Lachnospiraceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	DegV,HATPase_c,HisKA,Hpt,Response_reg
PNCOCPKN_01212	877424.ATWC01000015_gene634	8.63e-202	606.0	COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia,27ISK@186928|unclassified Lachnospiraceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,GAF_2,HATPase_c,HisKA,Hpt,Response_reg
PNCOCPKN_01213	877424.ATWC01000015_gene633	9.78e-133	389.0	COG3437@1|root,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,27IRU@186928|unclassified Lachnospiraceae	186801|Clostridia	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
PNCOCPKN_01214	585394.RHOM_13850	1.88e-205	577.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
PNCOCPKN_01215	585394.RHOM_13855	2.05e-93	278.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB_1	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
PNCOCPKN_01216	1341157.RF007C_10565	1.93e-173	489.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,3WG9Z@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
PNCOCPKN_01217	1298920.KI911353_gene3328	1.27e-264	730.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,21XFB@1506553|Lachnoclostridium	186801|Clostridia	E	Psort location Cytoplasmic, score 9.98	MET17	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
PNCOCPKN_01218	622312.ROSEINA2194_03130	2e-92	271.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia	186801|Clostridia	C	assembly protein, NifU family	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
PNCOCPKN_01219	622312.ROSEINA2194_03131	1.69e-246	681.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
PNCOCPKN_01221	180332.JTGN01000006_gene3154	5.14e-173	496.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia	186801|Clostridia	M	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
PNCOCPKN_01223	1226325.HMPREF1548_05938	2.85e-65	200.0	COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,24MSE@186801|Clostridia,36KQ7@31979|Clostridiaceae	186801|Clostridia	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
PNCOCPKN_01224	585394.RHOM_13905	0.0	1196.0	COG0119@1|root,COG2207@1|root,COG0119@2|Bacteria,COG2207@2|Bacteria,1TP4Y@1239|Firmicutes,2485A@186801|Clostridia	186801|Clostridia	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,HTH_18,LeuA_dimer
PNCOCPKN_01225	471875.RUMLAC_00843	4.72e-63	199.0	28PZ1@1|root,2ZCII@2|Bacteria,1V2GX@1239|Firmicutes,24IE1@186801|Clostridia,3WK3Z@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function, E. rectale Gene description (DUF3877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3877
PNCOCPKN_01226	622312.ROSEINA2194_00788	6.32e-83	247.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
PNCOCPKN_01227	1235793.C809_01839	2.26e-54	171.0	COG3695@1|root,COG3695@2|Bacteria,1UIU9@1239|Firmicutes,25ES2@186801|Clostridia,27UK4@186928|unclassified Lachnospiraceae	186801|Clostridia	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
PNCOCPKN_01228	622312.ROSEINA2194_00787	3.71e-302	835.0	COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,24978@186801|Clostridia	186801|Clostridia	P	Sulfate transporter	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
PNCOCPKN_01230	411461.DORFOR_00949	2.24e-28	111.0	2CJI5@1|root,32SA3@2|Bacteria,1VAH5@1239|Firmicutes,24MTX@186801|Clostridia,27VSK@189330|Dorea	186801|Clostridia	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
PNCOCPKN_01231	622312.ROSEINA2194_01022	3.22e-78	247.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,1V48S@1239|Firmicutes,24F7N@186801|Clostridia	186801|Clostridia	KT	transcriptional regulator	bltR	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
PNCOCPKN_01232	622312.ROSEINA2194_01023	5.08e-173	498.0	COG0534@1|root,COG0534@2|Bacteria,1TPPJ@1239|Firmicutes,25AZE@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PNCOCPKN_01233	585394.RHOM_13940	6.63e-86	254.0	COG0517@1|root,COG0517@2|Bacteria,1V7XE@1239|Firmicutes,24HF5@186801|Clostridia	186801|Clostridia	S	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
PNCOCPKN_01234	471875.RUMLAC_02178	2.52e-80	239.0	COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,24DGQ@186801|Clostridia	186801|Clostridia	L	PFAM Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
PNCOCPKN_01242	33035.JPJF01000016_gene4083	1.94e-63	201.0	2DIV4@1|root,30473@2|Bacteria,1V5EC@1239|Firmicutes,24IZE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01243	411463.EUBVEN_02693	1.87e-138	395.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6Q@186801|Clostridia,25VMP@186806|Eubacteriaceae	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
PNCOCPKN_01244	585394.RHOM_14685	8.34e-38	127.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01165	ATP-synt_C
PNCOCPKN_01245	411463.EUBVEN_02695	5.02e-62	196.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,24RWR@186801|Clostridia,25X82@186806|Eubacteriaceae	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
PNCOCPKN_01246	622312.ROSEINA2194_02212	1.64e-62	197.0	COG0712@1|root,COG0712@2|Bacteria,1UI0C@1239|Firmicutes,24G5C@186801|Clostridia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
PNCOCPKN_01247	622312.ROSEINA2194_02211	0.0	877.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP
PNCOCPKN_01248	585394.RHOM_14665	1.52e-175	493.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
PNCOCPKN_01249	585394.RHOM_14660	0.0	871.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
PNCOCPKN_01250	585394.RHOM_14655	1.05e-77	233.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
PNCOCPKN_01251	658086.HMPREF0994_01674	1.76e-68	222.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1V41T@1239|Firmicutes,25B4Q@186801|Clostridia,27TZT@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
PNCOCPKN_01252	397291.C804_03759	0.0	1060.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,27IMH@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
PNCOCPKN_01253	622312.ROSEINA2194_00571	0.0	1215.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolase family 3 N-terminal domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
PNCOCPKN_01254	411474.COPEUT_01236	2.02e-298	892.0	COG4124@1|root,COG4733@1|root,COG4124@2|Bacteria,COG4733@2|Bacteria,1TSXQ@1239|Firmicutes,24CRT@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 26 family	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	CBM27,CBM_11,CW_binding_1,Glyco_hydro_26,Gram_pos_anchor,SLH
PNCOCPKN_01255	641107.CDLVIII_5765	6.76e-100	298.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,36E89@31979|Clostridiaceae	186801|Clostridia	E	ABC transporter	-	-	-	ko:K10010	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.10,3.A.1.3.14	-	-	ABC_tran
PNCOCPKN_01256	641107.CDLVIII_5764	9.19e-81	248.0	COG0765@1|root,COG0765@2|Bacteria,1TPQ8@1239|Firmicutes,24BX1@186801|Clostridia,36FAP@31979|Clostridiaceae	186801|Clostridia	E	acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine	-	-	-	ko:K10009	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.10,3.A.1.3.14	-	-	BPD_transp_1
PNCOCPKN_01257	794846.AJQU01000046_gene4554	1.12e-76	241.0	COG0834@1|root,COG0834@2|Bacteria,1MXME@1224|Proteobacteria,2TT4J@28211|Alphaproteobacteria,4BBEK@82115|Rhizobiaceae	28211|Alphaproteobacteria	ET	belongs to the bacterial solute-binding protein 3 family	tcyA	-	-	ko:K02424	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3.10,3.A.1.3.14	-	-	SBP_bac_3
PNCOCPKN_01258	1410633.JHWR01000001_gene1255	9.02e-127	395.0	COG2200@1|root,COG2200@2|Bacteria,1V15N@1239|Firmicutes,24C2G@186801|Clostridia,27K15@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL
PNCOCPKN_01259	585394.RHOM_06170	0.0	1023.0	COG3867@1|root,COG3867@2|Bacteria,1TQDZ@1239|Firmicutes,24CPM@186801|Clostridia	186801|Clostridia	G	arabinogalactan	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,Glyco_hydro_53
PNCOCPKN_01260	585394.RHOM_08575	2.87e-185	550.0	COG0840@1|root,COG0840@2|Bacteria,1UYFA@1239|Firmicutes,24F3M@186801|Clostridia	186801|Clostridia	NT	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal,PilZ
PNCOCPKN_01261	622312.ROSEINA2194_00846	1e-95	296.0	2DNG5@1|root,32XBR@2|Bacteria,1V8W9@1239|Firmicutes,24M9E@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LprI
PNCOCPKN_01262	658086.HMPREF0994_03302	3.42e-52	168.0	COG2315@1|root,COG2315@2|Bacteria	2|Bacteria	V	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
PNCOCPKN_01263	585394.RHOM_00455	4.98e-186	525.0	COG2199@1|root,COG2199@2|Bacteria,1V1A1@1239|Firmicutes,24CYN@186801|Clostridia	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
PNCOCPKN_01264	658086.HMPREF0994_03302	4.43e-25	97.4	COG2315@1|root,COG2315@2|Bacteria	2|Bacteria	V	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
PNCOCPKN_01265	397291.C804_02931	1.92e-108	325.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,27UBJ@186928|unclassified Lachnospiraceae	186801|Clostridia	GK	ROK family	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI,ROK
PNCOCPKN_01266	397288.C806_01642	2.36e-118	354.0	COG1609@1|root,COG1609@2|Bacteria,1TT82@1239|Firmicutes,24G8D@186801|Clostridia,27QNK@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR,Peripla_BP_1
PNCOCPKN_01267	702450.CUW_2163	4.21e-190	541.0	COG3538@1|root,COG3538@2|Bacteria,1TRJI@1239|Firmicutes,3VPJX@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Pfam:DUF1237	-	-	-	ko:K09704	-	-	-	-	ko00000	-	-	-	Glyco_hydro_125
PNCOCPKN_01268	702450.CUW_2164	0.0	1151.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,3VPJS@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
PNCOCPKN_01269	397291.C804_02930	0.0	1297.0	COG3291@1|root,COG4724@1|root,COG3291@2|Bacteria,COG4724@2|Bacteria,1TPGB@1239|Firmicutes,24AII@186801|Clostridia	186801|Clostridia	G	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_85,PKD
PNCOCPKN_01270	1280673.AUJJ01000001_gene2237	3.66e-139	405.0	COG1609@1|root,COG1609@2|Bacteria,1TRG8@1239|Firmicutes,249CT@186801|Clostridia,4BZ5Y@830|Butyrivibrio	186801|Clostridia	K	Periplasmic binding protein-like domain	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
PNCOCPKN_01271	1280676.AUJO01000002_gene1480	6.37e-194	541.0	COG4209@1|root,COG4209@2|Bacteria,1TQFY@1239|Firmicutes,24923@186801|Clostridia,4BX4G@830|Butyrivibrio	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
PNCOCPKN_01272	1280676.AUJO01000002_gene1479	1.79e-175	494.0	COG0395@1|root,COG0395@2|Bacteria,1TP1G@1239|Firmicutes,247T2@186801|Clostridia,4C1Y7@830|Butyrivibrio	186801|Clostridia	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K17320	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
PNCOCPKN_01273	1280676.AUJO01000002_gene1478	5.44e-257	716.0	COG1653@1|root,COG1653@2|Bacteria,1TPWV@1239|Firmicutes,24AWQ@186801|Clostridia,4BYV9@830|Butyrivibrio	186801|Clostridia	G	Domain of unknown function (DUF3502)	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	DUF3502,SBP_bac_1,SBP_bac_8
PNCOCPKN_01274	397291.C804_02928	2.22e-217	602.0	COG2152@1|root,COG2152@2|Bacteria,1TQE7@1239|Firmicutes,249D0@186801|Clostridia,27JZU@186928|unclassified Lachnospiraceae	186801|Clostridia	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	2.4.1.319,2.4.1.320	ko:K18785	-	-	R10811,R10829	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
PNCOCPKN_01275	457412.RSAG_02071	0.0	936.0	COG1874@1|root,COG1874@2|Bacteria,1UZRC@1239|Firmicutes,24EDS@186801|Clostridia	186801|Clostridia	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01276	658086.HMPREF0994_01029	5.86e-246	709.0	28I74@1|root,2Z8A0@2|Bacteria,1VR23@1239|Firmicutes	1239|Firmicutes	S	COG NOG26804 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01277	397291.C804_02929	0.0	1614.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,248VH@186801|Clostridia,27KWU@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
PNCOCPKN_01278	1128421.JAGA01000003_gene2954	9.5e-31	130.0	COG2211@1|root,COG2211@2|Bacteria,2NR8E@2323|unclassified Bacteria	2|Bacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PNCOCPKN_01279	1195236.CTER_1937	4.71e-263	753.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia	186801|Clostridia	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
PNCOCPKN_01280	658086.HMPREF0994_03950	1.96e-210	608.0	COG3525@1|root,COG3525@2|Bacteria,1TSXM@1239|Firmicutes,248U1@186801|Clostridia,27QES@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolase family 20, domain 2	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_20,Glyco_hydro_20b
PNCOCPKN_01281	622312.ROSEINA2194_03990	2.21e-102	299.0	COG2002@1|root,COG2002@2|Bacteria,1V02A@1239|Firmicutes,248XR@186801|Clostridia	186801|Clostridia	K	stage V sporulation protein T	spoVT	-	-	ko:K04769	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin,SpoVT_C
PNCOCPKN_01282	622312.ROSEINA2194_03989	2.87e-168	479.0	COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,24BN3@186801|Clostridia	186801|Clostridia	L	Ser Thr phosphatase family protein	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
PNCOCPKN_01283	622312.ROSEINA2194_03988	2.63e-139	422.0	COG4717@1|root,COG4717@2|Bacteria,1TQP3@1239|Firmicutes,24E0A@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23,AAA_27
PNCOCPKN_01284	622312.ROSEINA2194_03986	0.0	965.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,248A4@186801|Clostridia	186801|Clostridia	M	penicillin-binding protein 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
PNCOCPKN_01285	622312.ROSEINA2194_03984	7.51e-195	543.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia	186801|Clostridia	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
PNCOCPKN_01286	585394.RHOM_14100	5.47e-125	360.0	COG3859@1|root,COG3859@2|Bacteria,1V1WX@1239|Firmicutes,24E4Z@186801|Clostridia	186801|Clostridia	S	Proton-coupled thiamine transporter YuaJ	yuaJ	-	-	ko:K16789	-	-	-	-	ko00000,ko02000	2.A.88.3	-	-	Thia_YuaJ
PNCOCPKN_01287	397291.C804_05932	2.15e-131	387.0	COG0614@1|root,COG0614@2|Bacteria,1UIJ9@1239|Firmicutes,25BH2@186801|Clostridia	186801|Clostridia	P	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
PNCOCPKN_01288	397291.C804_04092	1.45e-162	474.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia,27TN6@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15755	HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase
PNCOCPKN_01289	585394.RHOM_14885	6.18e-37	130.0	COG1669@1|root,COG1669@2|Bacteria,1VBYU@1239|Firmicutes,24N0Y@186801|Clostridia	186801|Clostridia	S	TIGRFAM nucleotidyltransferase substrate binding protein, HI0074 family	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2,NTase_sub_bind
PNCOCPKN_01290	1469948.JPNB01000001_gene1957	6.41e-57	181.0	COG0386@1|root,COG0386@2|Bacteria,1V3M3@1239|Firmicutes,24HGF@186801|Clostridia,36IXW@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the glutathione peroxidase family	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
PNCOCPKN_01291	397291.C804_05931	1.38e-113	334.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,27MTD@186928|unclassified Lachnospiraceae	186801|Clostridia	HP	ATPases associated with a variety of cellular activities	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
PNCOCPKN_01292	397291.C804_05930	1.74e-142	412.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,24BGM@186801|Clostridia,27U55@186928|unclassified Lachnospiraceae	186801|Clostridia	P	FecCD transport family	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
PNCOCPKN_01293	1262449.CP6013_1068	1.05e-34	121.0	COG1733@1|root,COG1733@2|Bacteria,1V707@1239|Firmicutes,24HCZ@186801|Clostridia,36IYB@31979|Clostridiaceae	186801|Clostridia	K	PFAM helix-turn-helix HxlR type	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
PNCOCPKN_01294	585394.RHOM_04795	2.62e-61	196.0	COG1342@1|root,COG1433@1|root,COG1342@2|Bacteria,COG1433@2|Bacteria,1TRMQ@1239|Firmicutes,25E8C@186801|Clostridia	186801|Clostridia	O	dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	DUF134,Nitro_FeMo-Co
PNCOCPKN_01295	1235802.C823_04050	2.91e-103	302.0	COG3506@1|root,COG3506@2|Bacteria,1TSXY@1239|Firmicutes,2484H@186801|Clostridia,25Y9J@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1349)	-	-	-	ko:K09702	-	-	-	-	ko00000	-	-	-	DUF1349
PNCOCPKN_01296	622312.ROSEINA2194_00219	1.78e-248	686.0	COG0738@1|root,COG0738@2|Bacteria,1TQPE@1239|Firmicutes,24AF8@186801|Clostridia	186801|Clostridia	G	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PNCOCPKN_01297	622312.ROSEINA2194_00218	4.76e-168	474.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1V0PV@1239|Firmicutes,24BUX@186801|Clostridia	186801|Clostridia	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
PNCOCPKN_01298	742765.HMPREF9457_03544	2.88e-51	163.0	COG2826@1|root,COG2826@2|Bacteria,1TQ0G@1239|Firmicutes,248WB@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38
PNCOCPKN_01299	1250278.JQNQ01000001_gene114	1.06e-136	440.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,4NEHR@976|Bacteroidetes,1HYJU@117743|Flavobacteriia	976|Bacteroidetes	L	Restriction	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,TaqI_C
PNCOCPKN_01300	999413.HMPREF1094_00559	2.99e-55	179.0	2DRUK@1|root,33D4I@2|Bacteria,1VMYD@1239|Firmicutes,3VTB3@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01302	469596.HMPREF9488_02258	8.32e-168	469.0	COG2856@1|root,COG2856@2|Bacteria,1TTI7@1239|Firmicutes,3VS92@526524|Erysipelotrichia	526524|Erysipelotrichia	E	IrrE N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
PNCOCPKN_01304	483218.BACPEC_01778	5.12e-139	393.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24ESY@186801|Clostridia	186801|Clostridia	K	Represses a number of genes involved in the response to DNA damage (SOS response)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,Peptidase_S24
PNCOCPKN_01305	469596.HMPREF9488_02256	1.87e-223	617.0	COG2378@1|root,COG2378@2|Bacteria,1TSA2@1239|Firmicutes,3VRQN@526524|Erysipelotrichia	526524|Erysipelotrichia	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
PNCOCPKN_01306	469596.HMPREF9488_02255	4.33e-154	432.0	COG4509@1|root,COG4509@2|Bacteria,1TRWN@1239|Firmicutes,3VQAI@526524|Erysipelotrichia	526524|Erysipelotrichia	S	sortase, SrtB family	srtB	-	-	-	-	-	-	-	-	-	-	-	Sortase
PNCOCPKN_01307	469596.HMPREF9488_02254	1.37e-60	189.0	2EI0N@1|root,33BS5@2|Bacteria,1VK70@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01308	411489.CLOL250_01602	0.0	2438.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	DUF4157,Haemagg_act,LRR_5,Peptidase_M64
PNCOCPKN_01309	457412.RSAG_01012	2.31e-188	529.0	COG3385@1|root,COG3385@2|Bacteria,1TRKC@1239|Firmicutes,24EUB@186801|Clostridia	186801|Clostridia	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
PNCOCPKN_01310	742765.HMPREF9457_02509	1.83e-59	183.0	2E3CH@1|root,334RE@2|Bacteria,1VI1B@1239|Firmicutes,24STQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01311	500632.CLONEX_00557	5.72e-104	300.0	2DN0Z@1|root,32UTR@2|Bacteria,1VDQ7@1239|Firmicutes,24NV1@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01312	742765.HMPREF9457_02511	6.33e-46	147.0	2E3CH@1|root,32YBT@2|Bacteria,1VHJT@1239|Firmicutes,24RED@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01313	411489.CLOL250_02627	1.58e-313	861.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,36DX4@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
PNCOCPKN_01314	585394.RHOM_15670	3.44e-93	274.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
PNCOCPKN_01315	622312.ROSEINA2194_00784	1.07e-54	178.0	2ECHQ@1|root,336FZ@2|Bacteria,1VI4C@1239|Firmicutes,24TFT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01316	622312.ROSEINA2194_00783	5.99e-204	568.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia	186801|Clostridia	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
PNCOCPKN_01317	585394.RHOM_15685	3.89e-170	477.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia	186801|Clostridia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
PNCOCPKN_01318	585394.RHOM_15690	8.34e-61	188.0	2CJXG@1|root,32SB0@2|Bacteria,1VAFJ@1239|Firmicutes,24MNI@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01319	622312.ROSEINA2194_00780	1.09e-175	496.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia	186801|Clostridia	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
PNCOCPKN_01320	585394.RHOM_15700	2.97e-221	612.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia	186801|Clostridia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
PNCOCPKN_01321	622312.ROSEINA2194_00777	1.13e-127	375.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia	186801|Clostridia	O	SPFH Band 7 PHB domain protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
PNCOCPKN_01322	585394.RHOM_14185	1.09e-117	348.0	COG0392@1|root,COG0392@2|Bacteria,1V2TI@1239|Firmicutes,24K1U@186801|Clostridia	186801|Clostridia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
PNCOCPKN_01323	622312.ROSEINA2194_04045	0.0	916.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
PNCOCPKN_01324	585394.RHOM_14195	3.18e-150	431.0	COG0770@1|root,COG0770@2|Bacteria,1TS8M@1239|Firmicutes,24CJW@186801|Clostridia	186801|Clostridia	M	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
PNCOCPKN_01325	585394.RHOM_14200	5.37e-186	521.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,248UR@186801|Clostridia	186801|Clostridia	CH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
PNCOCPKN_01326	585394.RHOM_14205	4.33e-154	438.0	COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,2485C@186801|Clostridia	186801|Clostridia	S	Phospholipase, patatin family	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
PNCOCPKN_01327	622312.ROSEINA2194_04052	1.76e-61	193.0	COG1585@1|root,COG1585@2|Bacteria,1VAS9@1239|Firmicutes,24MRQ@186801|Clostridia	186801|Clostridia	OU	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
PNCOCPKN_01328	585394.RHOM_14215	6.11e-53	178.0	2DU28@1|root,33NME@2|Bacteria,1VMV6@1239|Firmicutes,24V3C@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01329	585394.RHOM_14220	3.39e-195	548.0	COG1619@1|root,COG1619@2|Bacteria,1TZSN@1239|Firmicutes,25CIH@186801|Clostridia	186801|Clostridia	V	proteins homologs of microcin C7 resistance protein MccF	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S66
PNCOCPKN_01331	140626.JHWB01000022_gene2115	5.03e-98	290.0	COG1011@1|root,COG1011@2|Bacteria,1V6I4@1239|Firmicutes,24JK7@186801|Clostridia	186801|Clostridia	S	HAD hydrolase, family IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
PNCOCPKN_01332	585394.RHOM_14265	9.8e-219	634.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
PNCOCPKN_01333	1256908.HMPREF0373_02016	1.54e-144	412.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,25V99@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PNCOCPKN_01334	585394.RHOM_14275	1.11e-101	310.0	COG0642@1|root,COG0642@2|Bacteria,1TQSG@1239|Firmicutes,25EB7@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
PNCOCPKN_01335	1235793.C809_02063	5.49e-123	354.0	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,249TG@186801|Clostridia,27IZY@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	graR	-	-	ko:K19082	ko02020,map02020	M00734,M00737	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
PNCOCPKN_01336	585394.RHOM_14285	6.01e-226	625.0	COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes,24842@186801|Clostridia	186801|Clostridia	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
PNCOCPKN_01337	585394.RHOM_15710	3.05e-143	425.0	COG3103@1|root,COG3773@1|root,COG3103@2|Bacteria,COG3773@2|Bacteria,1TRFW@1239|Firmicutes,24DDK@186801|Clostridia	186801|Clostridia	MT	Cell Wall Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_2,SH3_3
PNCOCPKN_01339	585394.RHOM_15725	1.15e-211	590.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
PNCOCPKN_01340	622312.ROSEINA2194_00772	3.52e-85	252.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia	186801|Clostridia	FG	PFAM Histidine triad (HIT) protein	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
PNCOCPKN_01341	585394.RHOM_15740	2.5e-200	559.0	COG0655@1|root,COG3255@1|root,COG0655@2|Bacteria,COG3255@2|Bacteria,1TT0Y@1239|Firmicutes,247MH@186801|Clostridia	186801|Clostridia	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
PNCOCPKN_01342	622312.ROSEINA2194_00769	8.14e-154	443.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,247PT@186801|Clostridia	186801|Clostridia	S	PFAM Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
PNCOCPKN_01343	585394.RHOM_15750	1.49e-75	246.0	COG1716@1|root,COG1716@2|Bacteria,1V550@1239|Firmicutes,24BVK@186801|Clostridia	186801|Clostridia	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
PNCOCPKN_01346	622312.ROSEINA2194_00764	2.27e-67	217.0	COG4961@1|root,COG4961@2|Bacteria,1V9E1@1239|Firmicutes,24ET0@186801|Clostridia	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TadE
PNCOCPKN_01347	585394.RHOM_15770	2.03e-104	328.0	2BXNJ@1|root,2ZC8M@2|Bacteria,1UYM5@1239|Firmicutes,24ASZ@186801|Clostridia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01348	397287.C807_03605	8.06e-11	58.2	2EHSI@1|root,33BI9@2|Bacteria,1VK7K@1239|Firmicutes,24UF9@186801|Clostridia,27QCR@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Putative Flagellin, Flp1-like, domain	-	-	-	-	-	-	-	-	-	-	-	-	Flp1_like
PNCOCPKN_01349	622312.ROSEINA2194_00761	1.08e-92	292.0	COG2064@1|root,COG2064@2|Bacteria,1V2C3@1239|Firmicutes,24AN4@186801|Clostridia	186801|Clostridia	NU	Psort location CytoplasmicMembrane, score	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
PNCOCPKN_01350	585394.RHOM_15785	5.76e-79	244.0	COG4965@1|root,COG4965@2|Bacteria,1V6PB@1239|Firmicutes,24JBR@186801|Clostridia	186801|Clostridia	U	Psort location CytoplasmicMembrane, score	tadB	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
PNCOCPKN_01351	585394.RHOM_15790	1.29e-195	554.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia	186801|Clostridia	U	Type II IV secretion system protein	ptlH	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
PNCOCPKN_01352	585394.RHOM_15795	9.43e-93	287.0	COG1192@1|root,COG1192@2|Bacteria,1V11K@1239|Firmicutes,24FDX@186801|Clostridia	186801|Clostridia	D	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
PNCOCPKN_01353	585394.RHOM_15800	1.64e-52	170.0	2EHCT@1|root,33B4M@2|Bacteria,1UPNG@1239|Firmicutes	1239|Firmicutes	S	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
PNCOCPKN_01355	1235790.C805_03392	5.65e-22	88.2	2EIA7@1|root,33C1J@2|Bacteria,1VMCK@1239|Firmicutes,24W47@186801|Clostridia,25XQS@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF2508)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2508
PNCOCPKN_01356	585394.RHOM_15815	2.02e-68	211.0	COG1516@1|root,COG1516@2|Bacteria,1VD1Q@1239|Firmicutes,24PMH@186801|Clostridia	186801|Clostridia	NOU	Flagellar protein FliS	-	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
PNCOCPKN_01357	585394.RHOM_15820	1.07e-199	571.0	COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia	186801|Clostridia	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	hag	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
PNCOCPKN_01358	585394.RHOM_15825	7.4e-41	134.0	COG2846@1|root,COG2846@2|Bacteria,1VET8@1239|Firmicutes,24QPY@186801|Clostridia	186801|Clostridia	D	cluster protein-associated redox disulfide domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858
PNCOCPKN_01359	585394.RHOM_15830	6.8e-127	368.0	COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,24BWV@186801|Clostridia	186801|Clostridia	NOT	Negative regulator of genetic competence	mecB	-	-	ko:K16511	-	-	-	-	ko00000	-	-	-	MecA
PNCOCPKN_01360	622312.ROSEINA2194_00751	1.54e-136	407.0	COG0515@1|root,COG0515@2|Bacteria,1V3N4@1239|Firmicutes,25B6W@186801|Clostridia	186801|Clostridia	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
PNCOCPKN_01362	585394.RHOM_15850	2.21e-297	827.0	COG3858@1|root,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,247YF@186801|Clostridia	186801|Clostridia	M	family 18	ydhD	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Cu_amine_oxidN1,Glyco_hydro_18,SH3_3
PNCOCPKN_01363	622312.ROSEINA2194_00744	2.27e-100	299.0	COG0860@1|root,COG0860@2|Bacteria,1TQ74@1239|Firmicutes,24FT2@186801|Clostridia	186801|Clostridia	M	N-Acetylmuramoyl-L-alanine amidase	cwlD	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
PNCOCPKN_01364	622312.ROSEINA2194_00743	0.0	1042.0	28ISF@1|root,2Z8RM@2|Bacteria,1TSK2@1239|Firmicutes,249Q2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01365	585394.RHOM_15865	0.0	1204.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
PNCOCPKN_01366	585394.RHOM_15870	0.0	1024.0	COG0457@1|root,COG0464@1|root,COG0457@2|Bacteria,COG0464@2|Bacteria,1TY3C@1239|Firmicutes,248IE@186801|Clostridia	186801|Clostridia	O	Psort location Cytoplasmic, score	SpoVK	-	-	-	-	-	-	-	-	-	-	-	TPR_8
PNCOCPKN_01367	585394.RHOM_15875	3.08e-201	571.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
PNCOCPKN_01368	585394.RHOM_15890	0.0	1386.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia	186801|Clostridia	C	aconitate hydratase	ybhJ	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
PNCOCPKN_01369	585394.RHOM_15900	0.0	974.0	COG5002@1|root,COG5002@2|Bacteria,1UM03@1239|Firmicutes,24F2S@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PNCOCPKN_01370	622312.ROSEINA2194_02189	2.29e-155	437.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia	186801|Clostridia	KT	response regulator receiver	phoP_1	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PNCOCPKN_01371	585394.RHOM_15910	6.81e-167	476.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia	186801|Clostridia	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
PNCOCPKN_01373	585394.RHOM_15935	2.81e-73	231.0	2C331@1|root,30RPK@2|Bacteria,1V3YF@1239|Firmicutes,24IF9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01374	622312.ROSEINA2194_00858	0.0	895.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia	186801|Clostridia	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
PNCOCPKN_01375	622312.ROSEINA2194_01478	1.95e-67	233.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1,sCache_2
PNCOCPKN_01376	585394.RHOM_14940	0.0	1146.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
PNCOCPKN_01377	585394.RHOM_15950	4.1e-268	744.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia	186801|Clostridia	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
PNCOCPKN_01378	585394.RHOM_15955	1.95e-164	463.0	COG3639@1|root,COG3639@2|Bacteria,1TQ73@1239|Firmicutes,24AGQ@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	phnE_2	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
PNCOCPKN_01379	585394.RHOM_15960	3.6e-162	457.0	COG3639@1|root,COG3639@2|Bacteria,1TR1S@1239|Firmicutes,24A7G@186801|Clostridia	186801|Clostridia	P	phosphonate ABC transporter, permease protein PhnE	phnE_1	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
PNCOCPKN_01380	585394.RHOM_15965	2.4e-157	444.0	COG3638@1|root,COG3638@2|Bacteria,1TQG6@1239|Firmicutes,249GS@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
PNCOCPKN_01381	585394.RHOM_15970	7.15e-199	558.0	COG3221@1|root,COG3221@2|Bacteria,1TR0H@1239|Firmicutes,24A3Q@186801|Clostridia	186801|Clostridia	P	ABC-type phosphate phosphonate transport system periplasmic component	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
PNCOCPKN_01382	585394.RHOM_15975	4.56e-165	469.0	COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,248K0@186801|Clostridia	186801|Clostridia	K	Transcriptional	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
PNCOCPKN_01383	1226325.HMPREF1548_01833	3.39e-92	278.0	COG0496@1|root,COG0496@2|Bacteria,1TS2T@1239|Firmicutes,24BI5@186801|Clostridia,36F35@31979|Clostridiaceae	186801|Clostridia	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
PNCOCPKN_01384	1430331.EP10_03905	1.08e-75	242.0	COG0827@1|root,COG0827@2|Bacteria,1UZYA@1239|Firmicutes	1239|Firmicutes	L	BsuBI/PstI restriction endonuclease C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	BsuBI_PstI_RE
PNCOCPKN_01385	411463.EUBVEN_00713	1.07e-113	352.0	COG0827@1|root,COG0827@2|Bacteria,1UXY1@1239|Firmicutes,24B3U@186801|Clostridia,25Y8Q@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	2.1.1.72	ko:K07317	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Eco57I,N6_Mtase
PNCOCPKN_01386	585394.RHOM_00600	3.61e-85	265.0	COG2720@1|root,COG2720@2|Bacteria,1V5AV@1239|Firmicutes,24HJP@186801|Clostridia	186801|Clostridia	V	vancomycin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,CW_binding_2,VanW
PNCOCPKN_01387	585394.RHOM_15990	1.24e-230	642.0	COG1228@1|root,COG1228@2|Bacteria,1TPNQ@1239|Firmicutes,248UT@186801|Clostridia	186801|Clostridia	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
PNCOCPKN_01388	140626.JHWB01000022_gene2044	9.41e-294	813.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
PNCOCPKN_01389	140626.JHWB01000022_gene2043	3.49e-35	121.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia	186801|Clostridia	G	phosphocarrier, HPr family	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
PNCOCPKN_01390	622312.ROSEINA2194_04380	0.0	999.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia	186801|Clostridia	G	Phosphotransferase System	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
PNCOCPKN_01391	622312.ROSEINA2194_04379	1.88e-176	496.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,249RK@186801|Clostridia	186801|Clostridia	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	pfkB	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
PNCOCPKN_01392	585394.RHOM_16010	2.03e-137	393.0	COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,2498W@186801|Clostridia	186801|Clostridia	K	transcriptional regulator DeoR family	fruR	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
PNCOCPKN_01393	585394.RHOM_16015	1.46e-73	228.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24F4A@186801|Clostridia	186801|Clostridia	G	phosphoglycerate mutase	-	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
PNCOCPKN_01394	1226325.HMPREF1548_02751	1.68e-73	237.0	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
PNCOCPKN_01395	1226325.HMPREF1548_02751	9.53e-77	244.0	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
PNCOCPKN_01396	515620.EUBELI_00788	1.04e-33	125.0	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia,25WQJ@186806|Eubacteriaceae	186801|Clostridia	S	Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
PNCOCPKN_01398	622312.ROSEINA2194_03516	9.68e-249	691.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PNCOCPKN_01399	622312.ROSEINA2194_04368	3.57e-79	236.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01195	ATP-synt_DE,ATP-synt_DE_N
PNCOCPKN_01400	622312.ROSEINA2194_04367	0.0	866.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
PNCOCPKN_01401	585394.RHOM_16030	1.41e-159	452.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
PNCOCPKN_01402	622312.ROSEINA2194_04365	0.0	926.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
PNCOCPKN_01403	622312.ROSEINA2194_04364	4.04e-101	296.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,24MSA@186801|Clostridia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
PNCOCPKN_01404	585394.RHOM_16045	4.29e-44	150.0	COG0711@1|root,COG0711@2|Bacteria,1V74H@1239|Firmicutes,25CRV@186801|Clostridia	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
PNCOCPKN_01405	1235802.C823_01323	1.62e-44	145.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,25XKI@186806|Eubacteriaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
PNCOCPKN_01406	585394.RHOM_16055	8.22e-154	435.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6Q@186801|Clostridia	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
PNCOCPKN_01407	622312.ROSEINA2194_04360	1.34e-68	210.0	2CFN0@1|root,32RUQ@2|Bacteria,1VD5D@1239|Firmicutes,24MN1@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_I
PNCOCPKN_01408	622312.ROSEINA2194_04359	9.24e-33	115.0	2EC2U@1|root,3361T@2|Bacteria,1VK1M@1239|Firmicutes,24RW0@186801|Clostridia	186801|Clostridia	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
PNCOCPKN_01409	585394.RHOM_16075	1.87e-102	297.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia	186801|Clostridia	F	cytidine and deoxycytidylate deaminase zinc-binding region	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
PNCOCPKN_01410	585394.RHOM_16080	1.24e-144	408.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,248FV@186801|Clostridia	186801|Clostridia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
PNCOCPKN_01411	622312.ROSEINA2194_04355	3.9e-80	241.0	COG0394@1|root,COG0394@2|Bacteria,1UIG5@1239|Firmicutes,25EMJ@186801|Clostridia	186801|Clostridia	T	Low molecular weight phosphotyrosine protein phosphatase	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
PNCOCPKN_01412	622312.ROSEINA2194_04354	5.17e-209	583.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
PNCOCPKN_01413	585394.RHOM_16095	2.45e-212	590.0	COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,249DZ@186801|Clostridia	186801|Clostridia	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
PNCOCPKN_01414	585394.RHOM_16100	3.41e-18	76.6	COG2768@1|root,COG2768@2|Bacteria,1VET2@1239|Firmicutes,24QUH@186801|Clostridia	186801|Clostridia	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
PNCOCPKN_01415	622312.ROSEINA2194_00870	1.66e-305	835.0	COG1373@1|root,COG1373@2|Bacteria,1TQ8Z@1239|Firmicutes,2499K@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
PNCOCPKN_01416	742722.HMPREF9463_01777	4.22e-18	79.3	COG1669@1|root,COG1669@2|Bacteria,2HVIG@201174|Actinobacteria,4CWW6@84998|Coriobacteriia	84998|Coriobacteriia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
PNCOCPKN_01418	585394.RHOM_16105	2.97e-79	244.0	COG0789@1|root,COG0789@2|Bacteria,1V4F1@1239|Firmicutes,24NFY@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, MerR family	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
PNCOCPKN_01419	585394.RHOM_16615	4.91e-301	823.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
PNCOCPKN_01420	585394.RHOM_16620	1.84e-86	256.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia	186801|Clostridia	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
PNCOCPKN_01421	585394.RHOM_16625	0.0	1115.0	COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,2484R@186801|Clostridia	186801|Clostridia	T	domain protein	yybT	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
PNCOCPKN_01422	622312.ROSEINA2194_04348	1.72e-38	140.0	COG3187@1|root,COG3187@2|Bacteria,1UMA9@1239|Firmicutes,25GDD@186801|Clostridia	186801|Clostridia	O	Heat shock protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01423	1235793.C809_00094	9.24e-172	486.0	COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,247M1@186801|Clostridia,27IAP@186928|unclassified Lachnospiraceae	186801|Clostridia	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
PNCOCPKN_01424	742735.HMPREF9467_00252	0.0	904.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia,21Z5X@1506553|Lachnoclostridium	186801|Clostridia	G	Glycosyl hydrolase family 36 C-terminal domain	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
PNCOCPKN_01425	1298920.KI911353_gene656	3.01e-276	770.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,21XQ0@1506553|Lachnoclostridium	186801|Clostridia	G	SMART alpha amylase catalytic sub domain	malL	-	3.2.1.1,3.2.1.10	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
PNCOCPKN_01426	1449050.JNLE01000003_gene575	2.05e-172	488.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,36F5I@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator, LacI family	-	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
PNCOCPKN_01427	1235793.C809_00086	1.74e-162	480.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia,27J9G@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolases family 32	-	-	3.2.1.80	ko:K03332	ko00051,map00051	-	R00879	-	ko00000,ko00001,ko01000	-	-	-	Big_2,CW_binding_1,Cadherin-like,DUF1080,Flg_new,Glyco_hydro_32C,Glyco_hydro_32N
PNCOCPKN_01428	1226325.HMPREF1548_04993	4.28e-297	817.0	COG0366@1|root,COG0366@2|Bacteria,1TR93@1239|Firmicutes,24AB0@186801|Clostridia,36FBK@31979|Clostridiaceae	186801|Clostridia	G	Sucrose phosphorylase	-	GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016758	2.4.1.329,2.4.1.7	ko:K00690,ko:K21350	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
PNCOCPKN_01429	1449050.JNLE01000003_gene571	6.72e-151	430.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia,36EZR@31979|Clostridiaceae	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
PNCOCPKN_01430	1449050.JNLE01000003_gene570	1.72e-177	498.0	COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,24ADV@186801|Clostridia,36DX1@31979|Clostridiaceae	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
PNCOCPKN_01431	1449050.JNLE01000003_gene569	1.94e-224	631.0	COG2182@1|root,COG2182@2|Bacteria,1UIC9@1239|Firmicutes,2499Z@186801|Clostridia,36UQF@31979|Clostridiaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
PNCOCPKN_01432	397291.C804_04832	2.18e-266	825.0	COG3209@1|root,COG3693@1|root,COG5492@1|root,COG3209@2|Bacteria,COG3693@2|Bacteria,COG5492@2|Bacteria,1UHTC@1239|Firmicutes,248KD@186801|Clostridia,27K6N@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Carbohydrate family 9 binding domain-like	-	-	3.2.1.4,3.2.1.8	ko:K01179,ko:K01181	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM9_1,CBM_4_9,Glyco_hydro_10,Polysacc_deac_1,SLH
PNCOCPKN_01433	411474.COPEUT_03042	1.39e-135	416.0	COG3867@1|root,COG3867@2|Bacteria,1TQDZ@1239|Firmicutes,24CPM@186801|Clostridia	186801|Clostridia	G	arabinogalactan	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,Big_4,CW_binding_1,Glyco_hydro_53
PNCOCPKN_01435	622312.ROSEINA2194_01915	1.18e-223	647.0	COG0840@1|root,COG5000@1|root,COG0840@2|Bacteria,COG5000@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal,dCache_1
PNCOCPKN_01436	585394.RHOM_16635	1.51e-57	178.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia	186801|Clostridia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
PNCOCPKN_01437	585394.RHOM_16640	8.85e-97	282.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia	186801|Clostridia	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
PNCOCPKN_01438	585394.RHOM_16645	4.62e-54	170.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
PNCOCPKN_01439	622312.ROSEINA2194_04343	1.32e-33	116.0	COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,24QKA@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
PNCOCPKN_01440	1123075.AUDP01000021_gene1398	3.69e-82	246.0	COG4894@1|root,COG4894@2|Bacteria,1V3WA@1239|Firmicutes,24MB0@186801|Clostridia,3WJCK@541000|Ruminococcaceae	186801|Clostridia	S	LURP-one-related	-	-	-	-	-	-	-	-	-	-	-	-	LOR
PNCOCPKN_01441	585394.RHOM_16655	1.52e-156	441.0	COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,2491J@186801|Clostridia	186801|Clostridia	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
PNCOCPKN_01442	483218.BACPEC_02910	7.56e-149	447.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,268D0@186813|unclassified Clostridiales	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
PNCOCPKN_01444	585394.RHOM_16660	4.38e-85	254.0	COG0700@1|root,COG0700@2|Bacteria,1V45M@1239|Firmicutes,24HSJ@186801|Clostridia	186801|Clostridia	S	PFAM nucleoside recognition domain protein	spmB	-	-	ko:K06374	-	-	-	-	ko00000	-	-	-	Gate
PNCOCPKN_01445	622312.ROSEINA2194_04339	7.24e-231	654.0	COG2199@1|root,COG2200@1|root,COG2200@2|Bacteria,COG3706@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,Response_reg
PNCOCPKN_01446	585394.RHOM_16670	4.05e-104	305.0	COG2715@1|root,COG2715@2|Bacteria,1V1E2@1239|Firmicutes,249G0@186801|Clostridia	186801|Clostridia	S	membrane protein required for spore maturation	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
PNCOCPKN_01447	585394.RHOM_16680	4.44e-234	666.0	COG4805@1|root,COG4805@2|Bacteria,1TREN@1239|Firmicutes,249U9@186801|Clostridia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
PNCOCPKN_01448	622312.ROSEINA2194_04330	2.39e-173	486.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia	186801|Clostridia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
PNCOCPKN_01449	642492.Clole_0437	1.16e-153	436.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport system ATPase component	-	-	-	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	M00188,M00436	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.2	-	-	ABC_tran
PNCOCPKN_01450	642492.Clole_0436	2.66e-134	386.0	COG0600@1|root,COG0600@2|Bacteria,1UYCY@1239|Firmicutes,249RH@186801|Clostridia	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050,ko:K15552	ko00920,ko02010,map00920,map02010	M00188,M00435	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4	-	-	BPD_transp_1
PNCOCPKN_01451	642492.Clole_0435	1.15e-166	476.0	COG0715@1|root,COG0715@2|Bacteria,1UYBA@1239|Firmicutes,24D4Q@186801|Clostridia	186801|Clostridia	P	TIGRFAM ABC transporter, substrate-binding protein, aliphatic	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,OmpA
PNCOCPKN_01452	642492.Clole_0434	1.98e-54	172.0	COG0347@1|root,COG0347@2|Bacteria,1V73J@1239|Firmicutes,24S5C@186801|Clostridia	186801|Clostridia	K	Belongs to the P(II) protein family	-	-	-	ko:K02590	-	-	-	-	ko00000	-	-	-	P-II
PNCOCPKN_01453	642492.Clole_0433	1.15e-49	160.0	COG0347@1|root,COG0347@2|Bacteria,1VASB@1239|Firmicutes,24J84@186801|Clostridia	186801|Clostridia	K	Belongs to the P(II) protein family	-	-	-	ko:K02589	-	-	-	-	ko00000	-	-	-	P-II
PNCOCPKN_01454	642492.Clole_0432	1.21e-281	785.0	COG0154@1|root,COG0154@2|Bacteria,1TSAQ@1239|Firmicutes,2483V@186801|Clostridia	186801|Clostridia	J	PFAM Amidase	-	-	3.5.1.54	ko:K01457	ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120	-	R00005	RC02756	ko00000,ko00001,ko01000	-	-	-	Amidase
PNCOCPKN_01455	642492.Clole_0431	0.0	1902.0	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,1TPUN@1239|Firmicutes,24E9Y@186801|Clostridia	186801|Clostridia	EI	Allophanate hydrolase subunit 1	-	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
PNCOCPKN_01456	642492.Clole_0430	1.73e-139	395.0	COG3665@1|root,COG3665@2|Bacteria,1UYE1@1239|Firmicutes,24DNP@186801|Clostridia	186801|Clostridia	S	TIGRFAM Urea carboxylase-associated protein 1	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
PNCOCPKN_01457	642492.Clole_0429	4.55e-155	437.0	COG3665@1|root,COG3665@2|Bacteria,1TQQF@1239|Firmicutes,24DHT@186801|Clostridia	186801|Clostridia	S	TIGRFAM Urea carboxylase-associated protein 2	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
PNCOCPKN_01458	642492.Clole_0428	3.2e-79	246.0	COG2197@1|root,COG2197@2|Bacteria,1V7ZQ@1239|Firmicutes,25BMW@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
PNCOCPKN_01459	1122915.AUGY01000071_gene4411	1.44e-40	148.0	COG0715@1|root,COG0715@2|Bacteria,1UY07@1239|Firmicutes,4HCR6@91061|Bacilli,26S7G@186822|Paenibacillaceae	91061|Bacilli	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
PNCOCPKN_01460	1123257.AUFV01000001_gene1768	3.53e-31	115.0	COG1335@1|root,COG1335@2|Bacteria	2|Bacteria	Q	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
PNCOCPKN_01461	457421.CBFG_03614	6.18e-19	88.2	COG2197@1|root,COG2197@2|Bacteria,1V7ZQ@1239|Firmicutes,25BMW@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
PNCOCPKN_01462	622312.ROSEINA2194_00855	9.51e-23	88.2	2EJZ9@1|root,33DPV@2|Bacteria,1VQST@1239|Firmicutes,254M5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01463	397290.C810_01918	7.59e-108	325.0	COG5492@1|root,COG5492@2|Bacteria,1V4A5@1239|Firmicutes,24IM0@186801|Clostridia,27MBH@186928|unclassified Lachnospiraceae	186801|Clostridia	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
PNCOCPKN_01464	1414720.CBYM010000015_gene2999	1.27e-119	349.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,36DPF@31979|Clostridiaceae	186801|Clostridia	HP	ABC transporter	fhuC	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
PNCOCPKN_01465	1414720.CBYM010000015_gene3000	2.48e-137	400.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,24BGM@186801|Clostridia,36EF1@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	fhuG	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
PNCOCPKN_01466	1216932.CM240_2981	4.93e-137	399.0	COG0609@1|root,COG0609@2|Bacteria,1TP13@1239|Firmicutes,24A8W@186801|Clostridia,36FH9@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	fhuB	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
PNCOCPKN_01467	545697.HMPREF0216_01953	1.55e-158	453.0	COG0614@1|root,COG0614@2|Bacteria,1TQMK@1239|Firmicutes,24B1M@186801|Clostridia,36EU7@31979|Clostridiaceae	186801|Clostridia	P	Periplasmic binding protein	fhuD	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
PNCOCPKN_01468	290402.Cbei_2136	2.29e-91	284.0	COG2207@1|root,COG2207@2|Bacteria,1V0EE@1239|Firmicutes,25B24@186801|Clostridia,36FJY@31979|Clostridiaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
PNCOCPKN_01469	585394.RHOM_16690	3.76e-144	410.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24BK7@186801|Clostridia	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
PNCOCPKN_01470	622312.ROSEINA2194_04328	4.33e-155	437.0	COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,249UH@186801|Clostridia	186801|Clostridia	S	Methyltransferase	yfiC	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS,Methyltransf_31
PNCOCPKN_01471	622312.ROSEINA2194_04327	1.29e-188	527.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,247Q6@186801|Clostridia	186801|Clostridia	K	domain protein	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
PNCOCPKN_01472	622312.ROSEINA2194_04326	8.13e-199	556.0	COG2812@1|root,COG2812@2|Bacteria,1VCQC@1239|Firmicutes,248U4@186801|Clostridia	186801|Clostridia	L	'dna polymerase iii	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
PNCOCPKN_01473	622312.ROSEINA2194_04325	4.89e-82	244.0	COG1728@1|root,COG1728@2|Bacteria,1VF6M@1239|Firmicutes,24S6C@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF327)	-	-	-	ko:K09770	-	-	-	-	ko00000	-	-	-	DUF327
PNCOCPKN_01474	622312.ROSEINA2194_04324	1.47e-96	286.0	COG0194@1|root,COG0194@2|Bacteria,1V3RZ@1239|Firmicutes,24HKC@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	gmk_1	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
PNCOCPKN_01475	622312.ROSEINA2194_04323	2.25e-207	591.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia	186801|Clostridia	E	Orn Lys Arg decarboxylase major	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
PNCOCPKN_01476	622312.ROSEINA2194_04322	2.62e-96	293.0	COG0746@1|root,COG0746@2|Bacteria	2|Bacteria	H	molybdenum cofactor guanylyltransferase activity	mobA	GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.77	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	DUF3305,NTP_transf_3
PNCOCPKN_01477	585394.RHOM_16730	7.23e-72	230.0	2EE0F@1|root,337V8@2|Bacteria,1VFWV@1239|Firmicutes,24SC3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01478	585394.RHOM_16735	1.32e-112	327.0	COG5340@1|root,COG5340@2|Bacteria,1USGA@1239|Firmicutes,24IEV@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, AbiEi antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
PNCOCPKN_01479	585394.RHOM_16745	3.15e-208	590.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
PNCOCPKN_01480	622312.ROSEINA2194_04317	1.13e-137	390.0	COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,248YR@186801|Clostridia	186801|Clostridia	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
PNCOCPKN_01482	622312.ROSEINA2194_04314	7.61e-235	652.0	COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,248JJ@186801|Clostridia	186801|Clostridia	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M42
PNCOCPKN_01483	1280688.AUJB01000009_gene1639	1.89e-15	88.2	2EAR0@1|root,334T8@2|Bacteria,1VAT6@1239|Firmicutes,24NCB@186801|Clostridia,3NGVW@46205|Pseudobutyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01484	585394.RHOM_16785	1.24e-276	762.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	mepA_2	-	-	-	-	-	-	-	-	-	-	-	MatE
PNCOCPKN_01485	1232453.BAIF02000044_gene3509	3.61e-18	80.5	28NU7@1|root,2ZBSM@2|Bacteria,1V2N8@1239|Firmicutes,24G4F@186801|Clostridia,26BKZ@186813|unclassified Clostridiales	186801|Clostridia	S	NOG32933 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01486	585394.RHOM_13430	2.83e-143	406.0	2DB6M@1|root,2Z7HS@2|Bacteria,1U8V8@1239|Firmicutes,249IN@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2871
PNCOCPKN_01487	483218.BACPEC_02760	2.52e-80	240.0	COG1846@1|root,COG1846@2|Bacteria,1V3G1@1239|Firmicutes,24G8T@186801|Clostridia,26CGS@186813|unclassified Clostridiales	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
PNCOCPKN_01488	483218.BACPEC_02215	2.33e-149	420.0	COG1838@1|root,COG1838@2|Bacteria,1TSJ8@1239|Firmicutes,25CDD@186801|Clostridia,269T7@186813|unclassified Clostridiales	186801|Clostridia	C	Fumarase C-terminus	ttdB	-	4.2.1.2,4.2.1.32	ko:K01678,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
PNCOCPKN_01489	483218.BACPEC_02216	6.18e-219	604.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,2685W@186813|unclassified Clostridiales	186801|Clostridia	C	Fumarate hydratase (Fumerase)	-	-	4.2.1.32	ko:K03779	ko00630,map00630	-	R00339	RC01382	ko00000,ko00001,ko01000	-	-	-	Fumerase
PNCOCPKN_01490	483218.BACPEC_02217	5.23e-278	764.0	COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,24D6M@186801|Clostridia,26A6P@186813|unclassified Clostridiales	186801|Clostridia	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp
PNCOCPKN_01491	483218.BACPEC_02218	1.63e-137	393.0	COG0583@1|root,COG0583@2|Bacteria,1TQ6Y@1239|Firmicutes,25C6V@186801|Clostridia	186801|Clostridia	K	lysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PNCOCPKN_01492	622312.ROSEINA2194_04272	1.5e-310	848.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PNCOCPKN_01493	622312.ROSEINA2194_04268	0.0	1155.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Alpha-amylase_N,Malt_amylase_C
PNCOCPKN_01494	483218.BACPEC_03095	5.73e-115	330.0	COG0716@1|root,COG0716@2|Bacteria,1VB6B@1239|Firmicutes,24GQN@186801|Clostridia,269I5@186813|unclassified Clostridiales	186801|Clostridia	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_3
PNCOCPKN_01495	585394.RHOM_01350	0.0	1122.0	COG2200@1|root,COG2200@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9
PNCOCPKN_01496	483218.BACPEC_03093	0.0	882.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,26B8C@186813|unclassified Clostridiales	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
PNCOCPKN_01497	397288.C806_00504	3.34e-58	187.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia,27KKZ@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
PNCOCPKN_01498	511680.BUTYVIB_00660	1.46e-19	90.1	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,4BYKX@830|Butyrivibrio	186801|Clostridia	L	Bacterial DNA topoisomeraes I ATP-binding domain	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
PNCOCPKN_01499	622312.ROSEINA2194_01137	4.52e-244	685.0	COG0577@1|root,COG0577@2|Bacteria,1V15I@1239|Firmicutes,24DNT@186801|Clostridia	2|Bacteria	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
PNCOCPKN_01500	622312.ROSEINA2194_01139	5.25e-103	302.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
PNCOCPKN_01501	622312.ROSEINA2194_03260	5.68e-126	360.0	COG5340@1|root,COG5340@2|Bacteria,1TQSK@1239|Firmicutes,247JC@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
PNCOCPKN_01502	1123263.AUKY01000003_gene293	8.54e-109	332.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,3VP6Z@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	-	-	-	-	-	-	-	-	-	-	-	-	Topoisom_bac,Toprim
PNCOCPKN_01503	1123263.AUKY01000003_gene294	3.46e-298	815.0	COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,3VQ6U@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
PNCOCPKN_01504	1123263.AUKY01000003_gene295	4.74e-15	73.6	28HUZ@1|root,2Z81G@2|Bacteria,1TS04@1239|Firmicutes,3VRWU@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Domain of unknown function (DUF4366)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4366
PNCOCPKN_01505	1410626.JHXB01000018_gene1524	1.15e-32	114.0	COG1396@1|root,COG1396@2|Bacteria,1VG1N@1239|Firmicutes,24QK8@186801|Clostridia,27P6W@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PNCOCPKN_01506	633697.EubceDRAFT1_2302	7.62e-271	743.0	COG1690@1|root,COG1690@2|Bacteria,1TPJ2@1239|Firmicutes,2481V@186801|Clostridia,25VDC@186806|Eubacteriaceae	186801|Clostridia	S	tRNA-splicing ligase RtcB	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
PNCOCPKN_01509	658086.HMPREF0994_03639	0.0	949.0	COG3534@1|root,COG3534@2|Bacteria,1TPG2@1239|Firmicutes,24AVP@186801|Clostridia	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-L-AF_C,Cadherin-like,DUF1080
PNCOCPKN_01510	658086.HMPREF0994_05738	6.77e-12	65.1	COG2755@1|root,COG2755@2|Bacteria,1USVU@1239|Firmicutes,24ZVY@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
PNCOCPKN_01511	642492.Clole_1281	5.3e-302	827.0	COG3534@1|root,COG3534@2|Bacteria,1TPJ0@1239|Firmicutes,25EH6@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
PNCOCPKN_01512	1226325.HMPREF1548_05324	3.74e-246	690.0	COG3664@1|root,COG3664@2|Bacteria,1TQGI@1239|Firmicutes,2490Q@186801|Clostridia,36GCA@31979|Clostridiaceae	186801|Clostridia	K	family 39	-	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	AraC_binding,Glyco_hydro_39,HTH_18
PNCOCPKN_01513	397291.C804_04886	2.35e-90	276.0	COG4977@1|root,COG4977@2|Bacteria,1UJZB@1239|Firmicutes,25FFH@186801|Clostridia,27NE9@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
PNCOCPKN_01514	518637.EUBIFOR_00731	2.23e-126	360.0	COG2020@1|root,COG2020@2|Bacteria,1V3IZ@1239|Firmicutes	1239|Firmicutes	O	Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF218,PEMT
PNCOCPKN_01515	1256908.HMPREF0373_02042	5.47e-176	489.0	COG3910@1|root,COG3910@2|Bacteria,1TSWP@1239|Firmicutes,249W3@186801|Clostridia,25UUH@186806|Eubacteriaceae	186801|Clostridia	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,AAA_23
PNCOCPKN_01516	1235792.C808_04909	1.72e-51	165.0	COG1943@1|root,COG1943@2|Bacteria,1TSQ0@1239|Firmicutes,25CMS@186801|Clostridia,27U60@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
PNCOCPKN_01517	585394.RHOM_05755	1.69e-117	363.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia	186801|Clostridia	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
PNCOCPKN_01518	658086.HMPREF0994_03639	0.0	956.0	COG3534@1|root,COG3534@2|Bacteria,1TPG2@1239|Firmicutes,24AVP@186801|Clostridia	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-L-AF_C,Cadherin-like,DUF1080
PNCOCPKN_01519	658086.HMPREF0994_03645	0.0	903.0	COG1653@1|root,COG3693@1|root,COG1653@2|Bacteria,COG3693@2|Bacteria,1UHTC@1239|Firmicutes,248KD@186801|Clostridia,27JSU@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolase family 10	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3,Beta_helix,Glyco_hydro_10,Peptidase_S9
PNCOCPKN_01520	877418.ATWV01000004_gene1861	1.9e-203	579.0	COG0534@1|root,COG0534@2|Bacteria,2J674@203691|Spirochaetes	203691|Spirochaetes	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PNCOCPKN_01522	1336245.JAGO01000001_gene1090	7.56e-43	153.0	COG0627@1|root,COG0627@2|Bacteria,1N3VN@1224|Proteobacteria,1RYER@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
PNCOCPKN_01523	1227349.C170_17832	2.18e-56	188.0	COG0627@1|root,COG0627@2|Bacteria,1TPA9@1239|Firmicutes,4HD64@91061|Bacilli,26RX9@186822|Paenibacillaceae	91061|Bacilli	S	esterase	estA	-	-	ko:K03930	-	-	-	-	ko00000,ko01000	-	CE1	-	Esterase
PNCOCPKN_01524	1280666.ATVS01000025_gene2877	1.54e-301	832.0	COG3534@1|root,COG3534@2|Bacteria,1VS1P@1239|Firmicutes,24BH3@186801|Clostridia,4C1VY@830|Butyrivibrio	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminus	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
PNCOCPKN_01525	658086.HMPREF0994_03785	3.57e-311	876.0	COG2382@1|root,COG2382@2|Bacteria,1V888@1239|Firmicutes,24CN5@186801|Clostridia,27M6U@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Dockerin_1,Esterase
PNCOCPKN_01526	658086.HMPREF0994_03797	1.97e-79	254.0	COG1609@1|root,COG1609@2|Bacteria,1V22B@1239|Firmicutes,24FZB@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
PNCOCPKN_01527	1280680.AUJU01000017_gene3826	3.26e-211	608.0	COG1653@1|root,COG1653@2|Bacteria,1V0Q4@1239|Firmicutes,24CCN@186801|Clostridia,4BYEJ@830|Butyrivibrio	186801|Clostridia	G	transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
PNCOCPKN_01528	658086.HMPREF0994_03647	2.34e-142	410.0	COG0395@1|root,COG0395@2|Bacteria,1TRB1@1239|Firmicutes,2488P@186801|Clostridia,27MH0@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K17320	ko02010,map02010	M00207,M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
PNCOCPKN_01529	658086.HMPREF0994_03648	3.05e-168	476.0	COG4209@1|root,COG4209@2|Bacteria,1TSTC@1239|Firmicutes,24AFM@186801|Clostridia,27M8N@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K17319	ko02010,map02010	M00207,M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
PNCOCPKN_01530	658086.HMPREF0994_03796	1.23e-190	553.0	COG3509@1|root,COG3509@2|Bacteria,1UZP5@1239|Firmicutes,24AU4@186801|Clostridia	186801|Clostridia	Q	Esterase PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Esterase_phd
PNCOCPKN_01531	1304880.JAGB01000002_gene1700	4.86e-170	495.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PNCOCPKN_01532	1449050.JNLE01000003_gene1418	7.58e-174	497.0	COG1680@1|root,COG1680@2|Bacteria,1UC2C@1239|Firmicutes,24B3Q@186801|Clostridia,36FP4@31979|Clostridiaceae	186801|Clostridia	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
PNCOCPKN_01533	658086.HMPREF0994_03790	2.21e-127	379.0	COG1680@1|root,COG1680@2|Bacteria,1UC2C@1239|Firmicutes,24B3Q@186801|Clostridia,27QDK@186928|unclassified Lachnospiraceae	186801|Clostridia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
PNCOCPKN_01534	411469.EUBHAL_01641	2.02e-23	96.3	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,248FK@186801|Clostridia,25VWT@186806|Eubacteriaceae	186801|Clostridia	S	Oxidoreductase, aldo keto reductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,MerR_1
PNCOCPKN_01535	1329250.WOSG25_090490	0.0	911.0	COG3507@1|root,COG3507@2|Bacteria,1TP5K@1239|Firmicutes,4HA16@91061|Bacilli,4AXIH@81850|Leuconostocaceae	91061|Bacilli	G	Glycosyl hydrolases family 43	xynB	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	DUF1349,Glyco_hydro_43
PNCOCPKN_01536	592026.GCWU0000282_002501	5.86e-89	270.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia	186801|Clostridia	K	Belongs to the ParB family	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
PNCOCPKN_01537	471875.RUMLAC_00973	1.44e-228	628.0	COG1533@1|root,COG1533@2|Bacteria,1TRIS@1239|Firmicutes,25CEW@186801|Clostridia,3WGZD@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
PNCOCPKN_01538	1280698.AUJS01000042_gene3266	6.17e-173	481.0	COG4422@1|root,COG4422@2|Bacteria,1TPRY@1239|Firmicutes,247VT@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
PNCOCPKN_01539	411460.RUMTOR_00953	2.03e-96	281.0	COG1846@1|root,COG1846@2|Bacteria,1V8KT@1239|Firmicutes,24B99@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, MarR family	mgrA	-	-	-	-	-	-	-	-	-	-	-	MarR
PNCOCPKN_01540	742735.HMPREF9467_02926	2.68e-165	479.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,2212F@1506553|Lachnoclostridium	186801|Clostridia	P	COG COG2211 Na melibiose symporter and related transporters	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
PNCOCPKN_01541	1232447.BAHW02000061_gene3415	2.17e-79	251.0	COG3039@1|root,COG3039@2|Bacteria,1TQF8@1239|Firmicutes,24AUQ@186801|Clostridia	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF772
PNCOCPKN_01542	592026.GCWU0000282_003088	2.54e-267	756.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia	186801|Clostridia	G	beta-galactosidase	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
PNCOCPKN_01543	1235798.C817_00586	4e-98	305.0	COG2207@1|root,COG2207@2|Bacteria,1TQD7@1239|Firmicutes,24CDM@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
PNCOCPKN_01544	511680.BUTYVIB_00693	3.44e-78	232.0	29606@1|root,2ZTAU@2|Bacteria,1V3IE@1239|Firmicutes,24HEK@186801|Clostridia,4C1U9@830|Butyrivibrio	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01545	511680.BUTYVIB_00694	6.44e-71	214.0	2DX1W@1|root,3430G@2|Bacteria,1VXDJ@1239|Firmicutes,251H4@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01546	411459.RUMOBE_02234	4.98e-47	154.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia	186801|Clostridia	K	Belongs to the ParB family	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
PNCOCPKN_01547	658086.HMPREF0994_05190	1.99e-127	365.0	291XE@1|root,2ZPH0@2|Bacteria,1V4WP@1239|Firmicutes,24I5M@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01548	411463.EUBVEN_01792	8.75e-60	186.0	COG0454@1|root,COG0456@2|Bacteria,1VAFS@1239|Firmicutes,24MUI@186801|Clostridia,25X27@186806|Eubacteriaceae	186801|Clostridia	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	ko:K03826	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10,Acetyltransf_7
PNCOCPKN_01549	658086.HMPREF0994_05630	0.0	961.0	COG1653@1|root,COG1653@2|Bacteria,1TPM0@1239|Firmicutes,24ARZ@186801|Clostridia,27IRQ@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
PNCOCPKN_01550	1256908.HMPREF0373_01142	4.6e-303	829.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,2481G@186801|Clostridia,25Y3K@186806|Eubacteriaceae	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PNCOCPKN_01551	33035.JPJF01000029_gene2115	1.52e-33	119.0	COG3862@1|root,COG3862@2|Bacteria,1VA4U@1239|Firmicutes,24MN9@186801|Clostridia,3Y0DY@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF1667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1667
PNCOCPKN_01552	411469.EUBHAL_02592	4.93e-243	667.0	COG0667@1|root,COG0667@2|Bacteria,1TQJC@1239|Firmicutes,25B10@186801|Clostridia,25VPB@186806|Eubacteriaceae	186801|Clostridia	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
PNCOCPKN_01553	411469.EUBHAL_02593	4.11e-175	489.0	COG0599@1|root,COG1917@1|root,COG0599@2|Bacteria,COG1917@2|Bacteria,1TRVH@1239|Firmicutes,249JY@186801|Clostridia,25VK4@186806|Eubacteriaceae	186801|Clostridia	S	conserved protein, contains double-stranded beta-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	CMD,Cupin_2
PNCOCPKN_01554	411459.RUMOBE_00715	5.91e-81	243.0	COG0716@1|root,COG0716@2|Bacteria,1V45R@1239|Firmicutes,24HDR@186801|Clostridia,3Y09P@572511|Blautia	186801|Clostridia	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
PNCOCPKN_01555	411459.RUMOBE_00716	3.52e-167	472.0	COG0583@1|root,COG0583@2|Bacteria,1TP77@1239|Firmicutes,248CX@186801|Clostridia,3Y01M@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PNCOCPKN_01556	483218.BACPEC_02561	7.54e-205	566.0	COG4974@1|root,COG4974@2|Bacteria,1TR57@1239|Firmicutes,24ACW@186801|Clostridia,26AN9@186813|unclassified Clostridiales	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
PNCOCPKN_01557	511680.BUTYVIB_00634	3.87e-63	210.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,4BZJF@830|Butyrivibrio	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
PNCOCPKN_01558	511680.BUTYVIB_00702	6.21e-12	63.9	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,247R1@186801|Clostridia,4BWG0@830|Butyrivibrio	186801|Clostridia	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
PNCOCPKN_01559	511680.BUTYVIB_00703	1.06e-89	269.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia,4BX3E@830|Butyrivibrio	186801|Clostridia	K	ParB-like nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
PNCOCPKN_01560	511680.BUTYVIB_00703	2.16e-64	203.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia,4BX3E@830|Butyrivibrio	186801|Clostridia	K	ParB-like nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
PNCOCPKN_01561	1123263.AUKY01000003_gene267	1.02e-66	202.0	2F3WC@1|root,33WNJ@2|Bacteria,1VVF5@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01562	1123263.AUKY01000003_gene268	0.0	889.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,3VQ03@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
PNCOCPKN_01563	552398.HMPREF0866_02781	3.72e-145	409.0	29YMG@1|root,30KGY@2|Bacteria,1V4T3@1239|Firmicutes,24I7T@186801|Clostridia,3WNKP@541000|Ruminococcaceae	186801|Clostridia	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
PNCOCPKN_01564	1123263.AUKY01000003_gene270	1.14e-48	155.0	COG3311@1|root,COG3311@2|Bacteria,1V8AE@1239|Firmicutes,3VU5J@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
PNCOCPKN_01565	552398.HMPREF0866_02783	1.41e-89	263.0	COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,24MWU@186801|Clostridia,3WPMW@541000|Ruminococcaceae	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
PNCOCPKN_01566	1123263.AUKY01000003_gene272	8.7e-42	138.0	COG1476@1|root,COG1476@2|Bacteria,1VA62@1239|Firmicutes	1239|Firmicutes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PNCOCPKN_01567	1203606.HMPREF1526_01744	7.37e-133	376.0	2CS32@1|root,32SQ6@2|Bacteria,1VBA5@1239|Firmicutes,24IJW@186801|Clostridia,36N11@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1492
PNCOCPKN_01568	1123263.AUKY01000003_gene274	3.33e-97	283.0	COG1476@1|root,COG1476@2|Bacteria,1VAJB@1239|Firmicutes,3VTUQ@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PNCOCPKN_01569	1123263.AUKY01000003_gene275	4.27e-126	359.0	COG2856@1|root,COG2856@2|Bacteria,1V1KH@1239|Firmicutes	1239|Firmicutes	E	Toxin-antitoxin system, toxin component	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
PNCOCPKN_01570	864565.HMPREF0379_0878	2.61e-28	112.0	COG1397@1|root,COG1397@2|Bacteria,1V7HC@1239|Firmicutes,24NRA@186801|Clostridia	186801|Clostridia	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01571	1123263.AUKY01000003_gene286	2.64e-316	864.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,3VQ3R@526524|Erysipelotrichia	526524|Erysipelotrichia	U	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
PNCOCPKN_01572	1123263.AUKY01000003_gene287	4.33e-49	157.0	2DT3K@1|root,33IIN@2|Bacteria,1VMNU@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01574	552398.HMPREF0866_02800	8.66e-70	211.0	296J0@1|root,2ZTUJ@2|Bacteria,1V4RY@1239|Firmicutes,24IWK@186801|Clostridia,3WMJW@541000|Ruminococcaceae	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
PNCOCPKN_01575	552398.HMPREF0866_02801	0.0	5322.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,1TPQA@1239|Firmicutes,2491X@186801|Clostridia,3WGBP@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
PNCOCPKN_01576	552398.HMPREF0866_02802	1.39e-40	134.0	2DP0F@1|root,332E5@2|Bacteria,1VGP4@1239|Firmicutes,24QXK@186801|Clostridia,3WQ1X@541000|Ruminococcaceae	186801|Clostridia	S	Putative tranposon-transfer assisting protein	-	-	-	-	-	-	-	-	-	-	-	-	TTRAP
PNCOCPKN_01577	626939.HMPREF9443_02181	8.81e-135	382.0	COG4227@1|root,COG4227@2|Bacteria,1UY22@1239|Firmicutes	1239|Firmicutes	L	YodL-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF4316,YodL
PNCOCPKN_01578	552398.HMPREF0866_02804	4.55e-143	403.0	COG1192@1|root,COG1192@2|Bacteria,1UM3K@1239|Firmicutes,25G9Q@186801|Clostridia,3WSTD@541000|Ruminococcaceae	186801|Clostridia	DL	Involved in chromosome partitioning	-	-	-	-	-	-	-	-	-	-	-	-	YodL
PNCOCPKN_01579	552398.HMPREF0866_02805	0.0	1320.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,3WGKN@541000|Ruminococcaceae	186801|Clostridia	L	DNA topoisomerase III	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
PNCOCPKN_01580	657322.FPR_01450	1.52e-84	250.0	2BAFA@1|root,323VS@2|Bacteria,1V915@1239|Firmicutes,24M6B@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01581	1226322.HMPREF1545_00002	1.2e-134	382.0	COG1136@1|root,COG1136@2|Bacteria,1V3NN@1239|Firmicutes,24I94@186801|Clostridia,2N8G1@216572|Oscillospiraceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PNCOCPKN_01582	411461.DORFOR_03242	0.0	1221.0	COG4652@1|root,COG4652@2|Bacteria,1U507@1239|Firmicutes,249H3@186801|Clostridia,27WFW@189330|Dorea	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF1430
PNCOCPKN_01583	1123263.AUKY01000003_gene295	1.15e-126	364.0	28HUZ@1|root,2Z81G@2|Bacteria,1TS04@1239|Firmicutes,3VRWU@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Domain of unknown function (DUF4366)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4366
PNCOCPKN_01584	626939.HMPREF9443_02176	1.66e-51	162.0	2B8HW@1|root,33ADW@2|Bacteria,1VP7Z@1239|Firmicutes	1239|Firmicutes	S	Domain of unknown function (DUF4315)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4315
PNCOCPKN_01585	552398.HMPREF0866_02809	0.0	1051.0	COG0791@1|root,COG0791@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia,3WMY7@541000|Ruminococcaceae	186801|Clostridia	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
PNCOCPKN_01586	552398.HMPREF0866_04564	0.0	1558.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,248ND@186801|Clostridia,3WG7K@541000|Ruminococcaceae	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
PNCOCPKN_01587	626939.HMPREF9443_02173	2.03e-91	268.0	COG3451@1|root,COG3451@2|Bacteria,1TTTV@1239|Firmicutes,4H841@909932|Negativicutes	909932|Negativicutes	U	PrgI family protein	-	-	-	-	-	-	-	-	-	-	-	-	PrgI
PNCOCPKN_01588	552398.HMPREF0866_02812	7.99e-194	539.0	28HUM@1|root,2Z81B@2|Bacteria,1TNZ2@1239|Firmicutes,248SU@186801|Clostridia,3WIBH@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01589	1121115.AXVN01000013_gene3176	2.69e-94	290.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3XYX0@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	tnpX	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
PNCOCPKN_01590	585394.RHOM_03735	2.29e-293	800.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia	186801|Clostridia	C	alcohol dehydrogenase	adh	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
PNCOCPKN_01591	585394.RHOM_06140	2.6e-304	870.0	28J8A@1|root,2Z93H@2|Bacteria,1UYEZ@1239|Firmicutes,24AV4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01592	411469.EUBHAL_02516	4.24e-178	504.0	COG0438@1|root,COG0438@2|Bacteria,1TPG9@1239|Firmicutes,24EAP@186801|Clostridia,25WEJ@186806|Eubacteriaceae	186801|Clostridia	M	Stealth protein CR2, conserved region 2	-	-	-	-	-	-	-	-	-	-	-	-	Stealth_CR1,Stealth_CR2,Stealth_CR3,Stealth_CR4
PNCOCPKN_01593	585394.RHOM_06135	0.0	1197.0	COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,247ND@186801|Clostridia	186801|Clostridia	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
PNCOCPKN_01594	1235792.C808_00459	7.87e-202	568.0	COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,248DW@186801|Clostridia,27IBJ@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	ko:K19955	-	-	-	-	ko00000,ko01000	-	-	-	Fe-ADH
PNCOCPKN_01595	585394.RHOM_04685	7.25e-213	600.0	COG0486@1|root,COG0486@2|Bacteria,1TQA8@1239|Firmicutes,247M4@186801|Clostridia	186801|Clostridia	S	Hydrogenase maturation GTPase HydF	hydF	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
PNCOCPKN_01596	585394.RHOM_04680	0.0	892.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia	186801|Clostridia	C	biosynthesis protein ThiH	hydG	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
PNCOCPKN_01597	585394.RHOM_04675	1.69e-194	547.0	COG0502@1|root,COG0502@2|Bacteria,1TPYQ@1239|Firmicutes,248H8@186801|Clostridia	186801|Clostridia	C	Iron-only hydrogenase maturation rSAM protein HydE	hydE	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
PNCOCPKN_01598	585394.RHOM_04670	5.81e-42	138.0	COG0864@1|root,COG0864@2|Bacteria,1VF9M@1239|Firmicutes,24QVJ@186801|Clostridia	186801|Clostridia	K	Iron-only hydrogenase system regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01599	515622.bpr_I1351	3.56e-52	167.0	COG0375@1|root,COG0375@2|Bacteria,1VABW@1239|Firmicutes,24NES@186801|Clostridia,4BZG4@830|Butyrivibrio	186801|Clostridia	S	Hydrogenase/urease nickel incorporation, metallochaperone, hypA	-	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
PNCOCPKN_01600	665956.HMPREF1032_02341	0.0	1468.0	COG0493@1|root,COG1143@1|root,COG4231@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,COG4231@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3WHYH@541000|Ruminococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_20,Fer4_9,Pyr_redox_2,Pyr_redox_3
PNCOCPKN_01601	515622.bpr_I1350	7.97e-128	367.0	COG0378@1|root,COG0378@2|Bacteria,1TS00@1239|Firmicutes,248T1@186801|Clostridia,4BXWJ@830|Butyrivibrio	186801|Clostridia	KO	CobW/HypB/UreG, nucleotide-binding domain	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
PNCOCPKN_01603	641112.ACOK01000114_gene2305	5.36e-80	240.0	COG5113@1|root,COG3236@2|Bacteria,1UY8T@1239|Firmicutes,2486K@186801|Clostridia,3WGS9@541000|Ruminococcaceae	186801|Clostridia	O	Domain of unknown function (DUF1768)	-	-	-	ko:K09935	-	-	-	-	ko00000	-	-	-	DUF1768
PNCOCPKN_01604	518637.EUBIFOR_02026	3.97e-77	231.0	29AZ1@1|root,2ZXY1@2|Bacteria,1V4KY@1239|Firmicutes,3VTCC@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01605	585501.HMPREF6123_1167	6.94e-118	341.0	28KQ0@1|root,2ZA7Z@2|Bacteria,1V4X7@1239|Firmicutes,24E87@186801|Clostridia,2PTNA@265975|Oribacterium	186801|Clostridia	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990
PNCOCPKN_01607	411489.CLOL250_02048	1.52e-18	100.0	COG3209@1|root,COG3210@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,1W1CQ@1239|Firmicutes,24Q72@186801|Clostridia,36NF6@31979|Clostridiaceae	186801|Clostridia	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01608	585394.RHOM_04645	1.09e-213	610.0	COG0726@1|root,COG0860@1|root,COG0726@2|Bacteria,COG0860@2|Bacteria,1TT1X@1239|Firmicutes,249PF@186801|Clostridia	186801|Clostridia	G	delta-lactam-biosynthetic de-N-acetylase	pdaA	-	-	ko:K01567	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
PNCOCPKN_01609	585394.RHOM_04640	4.3e-216	605.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
PNCOCPKN_01610	585394.RHOM_04635	0.0	1140.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
PNCOCPKN_01611	642492.Clole_2676	0.0	1194.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,248WR@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF5110,Glyco_hydro_31
PNCOCPKN_01612	642492.Clole_2677	2.3e-315	887.0	COG4447@1|root,COG4447@2|Bacteria,1VJ96@1239|Firmicutes	1239|Firmicutes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01613	411462.DORLON_00274	6.04e-187	531.0	COG0037@1|root,COG0607@1|root,COG0037@2|Bacteria,COG0607@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia,27VSU@189330|Dorea	186801|Clostridia	H	ATPase of the PP-loop superfamily implicated in cell cycle control	ttcA	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3,Rhodanese
PNCOCPKN_01614	622312.ROSEINA2194_04128	3.06e-314	861.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
PNCOCPKN_01615	585394.RHOM_11105	5.42e-192	534.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
PNCOCPKN_01616	585394.RHOM_11110	2.84e-270	741.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,25E6I@186801|Clostridia	186801|Clostridia	E	PFAM Cys Met metabolism	mccB	-	2.5.1.48,4.4.1.8	ko:K01739,ko:K01760	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
PNCOCPKN_01617	585394.RHOM_11115	2.25e-146	418.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UZ8Y@1239|Firmicutes,248SM@186801|Clostridia	186801|Clostridia	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
PNCOCPKN_01618	585394.RHOM_11120	0.0	897.0	COG1227@1|root,COG4109@1|root,COG1227@2|Bacteria,COG4109@2|Bacteria,1TPH6@1239|Firmicutes,248RQ@186801|Clostridia	186801|Clostridia	C	domain protein	ppaC	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
PNCOCPKN_01619	585394.RHOM_11125	4.48e-44	159.0	2E4NI@1|root,32ZHC@2|Bacteria,1VGQR@1239|Firmicutes,24RYT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01620	622312.ROSEINA2194_04139	0.0	886.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia	186801|Clostridia	G	pts system	nagE	-	2.7.1.193	ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	M00267	R05199	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7	-	-	PTS_EIIB,PTS_EIIC
PNCOCPKN_01621	622312.ROSEINA2194_04140	2.23e-89	264.0	COG2190@1|root,COG2190@2|Bacteria,1VAEB@1239|Firmicutes	1239|Firmicutes	G	PTS system, glucose subfamily, IIA	ptbA	-	-	ko:K02755,ko:K02756,ko:K02757,ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	M00265,M00266,M00268,M00270,M00271,M00272,M00303,M00806	R02738,R02780,R04111,R04394,R05132,R08559	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1,4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
PNCOCPKN_01622	622312.ROSEINA2194_04141	5.47e-175	490.0	COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,24931@186801|Clostridia	186801|Clostridia	K	transcriptional antiterminator	licT	-	-	ko:K03488	-	-	-	-	ko00000,ko03000	-	-	-	CAT_RBD,PRD
PNCOCPKN_01623	622312.ROSEINA2194_04142	1.56e-46	150.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
PNCOCPKN_01624	622312.ROSEINA2194_04143	0.0	919.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
PNCOCPKN_01625	622312.ROSEINA2194_04145	0.0	2296.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia	186801|Clostridia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
PNCOCPKN_01626	585394.RHOM_04830	0.0	1102.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,SBP_bac_3
PNCOCPKN_01627	585394.RHOM_04825	0.0	1025.0	COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,248ST@186801|Clostridia	186801|Clostridia	S	ABC transporter	ykpA	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
PNCOCPKN_01628	1449050.JNLE01000003_gene106	5.64e-12	73.6	2EG3M@1|root,339VN@2|Bacteria,1VN0Z@1239|Firmicutes,24UD6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01629	500632.CLONEX_03904	2.02e-84	256.0	COG0546@1|root,COG0546@2|Bacteria,1V1FQ@1239|Firmicutes,24G1U@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	nt5e	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
PNCOCPKN_01630	622312.ROSEINA2194_04469	5.1e-201	566.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
PNCOCPKN_01631	585394.RHOM_05120	1.66e-190	544.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia	186801|Clostridia	S	Stage V sporulation protein B	spoVB	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
PNCOCPKN_01632	483218.BACPEC_02966	1.55e-111	333.0	COG0484@1|root,COG0484@2|Bacteria,1TS44@1239|Firmicutes,24A9N@186801|Clostridia,26A1M@186813|unclassified Clostridiales	186801|Clostridia	O	DnaJ molecular chaperone homology domain	CbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
PNCOCPKN_01633	1160721.RBI_I01639	5.82e-75	234.0	COG0726@1|root,COG0726@2|Bacteria,1V8XF@1239|Firmicutes,24JZT@186801|Clostridia,3WIMA@541000|Ruminococcaceae	186801|Clostridia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1,Polysacc_deac_1
PNCOCPKN_01634	411474.COPEUT_00455	0.0	1248.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
PNCOCPKN_01635	515620.EUBELI_01734	4.4e-230	644.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,25V84@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PNCOCPKN_01636	397291.C804_05617	5.09e-94	278.0	COG1443@1|root,COG1443@2|Bacteria,1V41D@1239|Firmicutes,24KU4@186801|Clostridia,27M9G@186928|unclassified Lachnospiraceae	186801|Clostridia	I	NUDIX domain	idi	-	-	-	-	-	-	-	-	-	-	-	NUDIX
PNCOCPKN_01638	622312.ROSEINA2194_03305	0.0	960.0	COG1961@1|root,COG1961@2|Bacteria,1TSXI@1239|Firmicutes,248RE@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
PNCOCPKN_01639	1235800.C819_00786	1.13e-240	681.0	COG1961@1|root,COG1961@2|Bacteria,1TQ8Y@1239|Firmicutes,247WD@186801|Clostridia,27T7X@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
PNCOCPKN_01640	622312.ROSEINA2194_01655	0.0	1045.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
PNCOCPKN_01641	622312.ROSEINA2194_01654	5.58e-53	167.0	2DMSX@1|root,32TG6@2|Bacteria,1VCKS@1239|Firmicutes,24P39@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01642	622312.ROSEINA2194_01652	0.0	1278.0	COG1199@1|root,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,25C6H@186801|Clostridia	186801|Clostridia	L	helicase involved in DNA repair and perhaps also replication	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Helicase_C_2
PNCOCPKN_01643	622312.ROSEINA2194_01646	1.61e-143	411.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
PNCOCPKN_01644	622312.ROSEINA2194_01645	1.71e-52	167.0	COG1191@1|root,COG1191@2|Bacteria,1VJ1U@1239|Firmicutes,24I8V@186801|Clostridia	186801|Clostridia	K	sigma factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4
PNCOCPKN_01645	622312.ROSEINA2194_01642	1.43e-290	795.0	COG3290@1|root,COG3290@2|Bacteria,1V46S@1239|Firmicutes,24KBY@186801|Clostridia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
PNCOCPKN_01648	622312.ROSEINA2194_03155	6.02e-105	310.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
PNCOCPKN_01649	622312.ROSEINA2194_03156	7.17e-235	647.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
PNCOCPKN_01650	585394.RHOM_02890	1.01e-73	227.0	2CB94@1|root,32XMH@2|Bacteria,1VCD1@1239|Firmicutes,24MX5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01651	622312.ROSEINA2194_03158	1.49e-189	531.0	COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,248EQ@186801|Clostridia	186801|Clostridia	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
PNCOCPKN_01652	585394.RHOM_02880	7.57e-26	97.4	2EJD6@1|root,33D47@2|Bacteria,1VKED@1239|Firmicutes,24T7S@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01653	622312.ROSEINA2194_03159	7.09e-72	219.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
PNCOCPKN_01654	622312.ROSEINA2194_03160	5.21e-129	370.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia	186801|Clostridia	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
PNCOCPKN_01655	622312.ROSEINA2194_03161	9.27e-91	266.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia	186801|Clostridia	K	Hydrolase, P-loop family	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
PNCOCPKN_01656	622312.ROSEINA2194_03162	2.43e-65	204.0	2AZ5D@1|root,31RC2@2|Bacteria,1V74Z@1239|Firmicutes,24KGW@186801|Clostridia	186801|Clostridia	S	YcxB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
PNCOCPKN_01657	622312.ROSEINA2194_00823	1.66e-113	329.0	COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,24E4V@186801|Clostridia	186801|Clostridia	S	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins	ribU	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
PNCOCPKN_01658	622312.ROSEINA2194_00824	0.0	1251.0	COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,248P0@186801|Clostridia	186801|Clostridia	K	Tex-like protein N-terminal domain	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
PNCOCPKN_01659	585394.RHOM_02840	9.56e-35	122.0	2EGCD@1|root,33A46@2|Bacteria,1VMG3@1239|Firmicutes,24UKI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01660	585394.RHOM_02835	3.14e-43	146.0	2DNZJ@1|root,32ZX7@2|Bacteria,1VHMI@1239|Firmicutes,24SBG@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
PNCOCPKN_01661	585394.RHOM_02825	2.13e-76	239.0	COG5523@1|root,COG5523@2|Bacteria,1VB3B@1239|Firmicutes,24N6Q@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
PNCOCPKN_01662	585394.RHOM_02820	8.28e-296	812.0	COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,2485Z@186801|Clostridia	186801|Clostridia	F	permease	pyrP	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
PNCOCPKN_01663	585394.RHOM_02815	4.45e-78	241.0	COG4758@1|root,COG4758@2|Bacteria,1V7WJ@1239|Firmicutes,24A1Z@186801|Clostridia	186801|Clostridia	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
PNCOCPKN_01664	397291.C804_03441	3.29e-72	221.0	COG3279@1|root,COG3279@2|Bacteria,1VBF7@1239|Firmicutes,24G1R@186801|Clostridia,27MWM@186928|unclassified Lachnospiraceae	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
PNCOCPKN_01665	585394.RHOM_02805	8.84e-169	475.0	COG0489@1|root,COG0489@2|Bacteria,1TQ34@1239|Firmicutes,24817@186801|Clostridia	186801|Clostridia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	-	-	-	-	-	-	-	-	-	ParA
PNCOCPKN_01666	585394.RHOM_02800	1.47e-214	598.0	COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,249C5@186801|Clostridia	186801|Clostridia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
PNCOCPKN_01668	1469948.JPNB01000002_gene3250	1.24e-199	563.0	COG1680@1|root,COG1680@2|Bacteria,1UC2C@1239|Firmicutes,24B3Q@186801|Clostridia,36FP4@31979|Clostridiaceae	186801|Clostridia	V	beta-lactamase	-	-	3.4.16.4	ko:K21469	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Beta-lactamase
PNCOCPKN_01669	1280694.AUJQ01000011_gene1768	7.42e-132	390.0	COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,249VN@186801|Clostridia,3NGIB@46205|Pseudobutyrivibrio	186801|Clostridia	J	tRNA synthetases class II (A)	alaXL	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
PNCOCPKN_01670	622312.ROSEINA2194_02126	4.16e-43	145.0	2FC79@1|root,344B3@2|Bacteria,1W1AZ@1239|Firmicutes,24W3X@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01671	1235793.C809_02110	5.44e-16	77.8	COG2768@1|root,COG2768@2|Bacteria,1TQAW@1239|Firmicutes,247IS@186801|Clostridia,27IRX@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Domain of unknown function (DUF362)	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4,Fer4_21,Fer4_6,Fer4_7
PNCOCPKN_01672	622312.ROSEINA2194_01738	8.77e-174	486.0	COG0703@1|root,COG1605@1|root,COG0703@2|Bacteria,COG1605@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,SKI
PNCOCPKN_01673	622312.ROSEINA2194_01737	5.19e-186	524.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,248MN@186801|Clostridia	186801|Clostridia	G	COG COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	siaP	-	-	ko:K21395	-	-	-	-	ko00000,ko02000	2.A.56.1	-	-	DctP
PNCOCPKN_01674	622312.ROSEINA2194_01736	1.88e-254	704.0	COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
PNCOCPKN_01675	622312.ROSEINA2194_01735	6.63e-98	290.0	COG3090@1|root,COG3090@2|Bacteria,1V3PZ@1239|Firmicutes,24HA7@186801|Clostridia	186801|Clostridia	G	COG COG3090 TRAP-type C4-dicarboxylate transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
PNCOCPKN_01676	1408312.JNJS01000001_gene1438	2.36e-139	398.0	COG0710@1|root,COG0710@2|Bacteria,1TSPN@1239|Firmicutes,249EX@186801|Clostridia,3NH3M@46205|Pseudobutyrivibrio	186801|Clostridia	E	Type I 3-dehydroquinase	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,SKI
PNCOCPKN_01677	622312.ROSEINA2194_01731	1.43e-259	715.0	COG0477@1|root,COG0477@2|Bacteria,1TS50@1239|Firmicutes,24BE2@186801|Clostridia	186801|Clostridia	EGP	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PNCOCPKN_01678	622312.ROSEINA2194_01730	2.24e-204	566.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
PNCOCPKN_01679	622312.ROSEINA2194_01729	4.99e-179	502.0	COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,24B1W@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PNCOCPKN_01680	622312.ROSEINA2194_01728	2.33e-127	369.0	COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,24B1W@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PNCOCPKN_01681	622312.ROSEINA2194_01725	0.0	1281.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia	186801|Clostridia	C	NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
PNCOCPKN_01682	622312.ROSEINA2194_01722	7.94e-207	572.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
PNCOCPKN_01683	411470.RUMGNA_03147	8.65e-64	198.0	COG0454@1|root,COG0456@2|Bacteria,1VDD6@1239|Firmicutes,24NEN@186801|Clostridia,3Y0NK@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
PNCOCPKN_01684	622312.ROSEINA2194_00591	0.0	1211.0	COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia	186801|Clostridia	S	Myosin-crossreactive antigen	-	-	4.2.1.53	ko:K10254	-	-	-	-	ko00000,ko01000	-	-	-	MCRA
PNCOCPKN_01685	1235800.C819_03126	2.51e-99	291.0	COG1309@1|root,COG1309@2|Bacteria,1UYIP@1239|Firmicutes,249K5@186801|Clostridia,27TME@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Transcriptional regulator C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
PNCOCPKN_01686	33035.JPJF01000032_gene2180	0.0	951.0	COG3534@1|root,COG3534@2|Bacteria,1TRY9@1239|Firmicutes,2497J@186801|Clostridia,3Y1AY@572511|Blautia	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminus	abfA	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
PNCOCPKN_01687	33035.JPJF01000032_gene2181	1.82e-164	464.0	COG0395@1|root,COG0395@2|Bacteria,1TT5G@1239|Firmicutes,249MU@186801|Clostridia,3Y17N@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17236	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	BPD_transp_1
PNCOCPKN_01688	33035.JPJF01000032_gene2182	2.43e-188	526.0	COG1175@1|root,COG1175@2|Bacteria,1TRSP@1239|Firmicutes,24906@186801|Clostridia,3Y17F@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17235	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	BPD_transp_1
PNCOCPKN_01689	33035.JPJF01000032_gene2183	3.93e-269	744.0	COG1653@1|root,COG1653@2|Bacteria,1TS9Z@1239|Firmicutes,2490T@186801|Clostridia	186801|Clostridia	G	Extracellular solute-binding protein	araN	-	-	ko:K17234	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	SBP_bac_1,SBP_bac_8
PNCOCPKN_01690	33035.JPJF01000032_gene2184	0.0	971.0	COG3533@1|root,COG3533@2|Bacteria,1TNYA@1239|Firmicutes,24841@186801|Clostridia,3Y0XI@572511|Blautia	186801|Clostridia	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
PNCOCPKN_01691	33035.JPJF01000032_gene2185	2.92e-179	507.0	COG1609@1|root,COG1609@2|Bacteria,1TRWK@1239|Firmicutes,24DAV@186801|Clostridia	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
PNCOCPKN_01692	622312.ROSEINA2194_02127	1.77e-176	502.0	COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,248FR@186801|Clostridia	186801|Clostridia	M	Monogalactosyldiacylglycerol synthase	-	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glycos_transf_1,MGDG_synth
PNCOCPKN_01693	622312.ROSEINA2194_02128	2.8e-76	234.0	COG0344@1|root,COG0344@2|Bacteria,1V798@1239|Firmicutes,24KR2@186801|Clostridia	186801|Clostridia	I	Belongs to the PlsY family	-	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
PNCOCPKN_01694	585394.RHOM_13085	1.04e-211	584.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia	186801|Clostridia	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
PNCOCPKN_01695	585394.RHOM_13095	4.32e-80	239.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,24JB0@186801|Clostridia	186801|Clostridia	S	YqeY-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
PNCOCPKN_01696	585394.RHOM_13100	9.68e-107	330.0	COG0791@1|root,COG3883@1|root,COG0791@2|Bacteria,COG3883@2|Bacteria,1UVYK@1239|Firmicutes,249G6@186801|Clostridia	186801|Clostridia	M	NlpC p60 family	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
PNCOCPKN_01697	585394.RHOM_13110	4.98e-228	645.0	COG1388@1|root,COG1388@2|Bacteria,1TSVC@1239|Firmicutes,248VQ@186801|Clostridia	186801|Clostridia	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794,LysM
PNCOCPKN_01698	585394.RHOM_13115	1.26e-46	150.0	COG4466@1|root,COG4466@2|Bacteria	2|Bacteria	S	Protein conserved in bacteria	veg	-	-	-	-	-	-	-	-	-	-	-	VEG
PNCOCPKN_01699	585394.RHOM_13120	2.53e-53	171.0	2DD3J@1|root,32U0T@2|Bacteria,1VB00@1239|Firmicutes,24N49@186801|Clostridia	186801|Clostridia	S	PrcB C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PrcB_C
PNCOCPKN_01700	585394.RHOM_13125	1.6e-146	416.0	COG0204@1|root,COG0204@2|Bacteria,1UMJA@1239|Firmicutes,249AV@186801|Clostridia	186801|Clostridia	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	plsC_1	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
PNCOCPKN_01701	622312.ROSEINA2194_02141	1.55e-254	708.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
PNCOCPKN_01702	622312.ROSEINA2194_02142	4.12e-207	578.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
PNCOCPKN_01704	622312.ROSEINA2194_03042	1.71e-143	412.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,247ST@186801|Clostridia	186801|Clostridia	T	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
PNCOCPKN_01705	585394.RHOM_02215	1.32e-107	311.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
PNCOCPKN_01707	622312.ROSEINA2194_02147	6.06e-135	388.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,247NA@186801|Clostridia	186801|Clostridia	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
PNCOCPKN_01708	585394.RHOM_02190	0.0	1408.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia	186801|Clostridia	C	Glycine radical	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
PNCOCPKN_01709	585394.RHOM_02185	1.01e-100	305.0	COG2199@1|root,COG2199@2|Bacteria,1UV0N@1239|Firmicutes,24NW2@186801|Clostridia	186801|Clostridia	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3
PNCOCPKN_01710	622312.ROSEINA2194_02152	2e-61	192.0	COG0622@1|root,COG0622@2|Bacteria,1V7VB@1239|Firmicutes,24PEZ@186801|Clostridia	186801|Clostridia	S	Phosphoesterase	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
PNCOCPKN_01711	1410625.JHWK01000005_gene1207	2.55e-170	481.0	COG4189@1|root,COG4189@2|Bacteria,1TPGD@1239|Firmicutes,248UW@186801|Clostridia,27K27@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
PNCOCPKN_01712	1280688.AUJB01000008_gene632	5.67e-30	108.0	2DPI5@1|root,3326E@2|Bacteria,1VIQZ@1239|Firmicutes,24UPV@186801|Clostridia,3NIA5@46205|Pseudobutyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01713	1410625.JHWK01000005_gene1204	1.37e-292	806.0	COG3534@1|root,COG3534@2|Bacteria,1TR7B@1239|Firmicutes,248ZA@186801|Clostridia,27T9K@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminus	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
PNCOCPKN_01714	1121115.AXVN01000012_gene3113	1.12e-188	528.0	COG3940@1|root,COG3940@2|Bacteria,1TRHI@1239|Firmicutes,24AG6@186801|Clostridia,3Y1H0@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
PNCOCPKN_01715	585394.RHOM_08550	1.06e-267	740.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia	186801|Clostridia	E	amino acid carrier protein	agcS	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
PNCOCPKN_01716	1280694.AUJQ01000008_gene158	6.93e-247	693.0	COG3507@1|root,COG3507@2|Bacteria,1TPHA@1239|Firmicutes,24AKT@186801|Clostridia,3NGF5@46205|Pseudobutyrivibrio	186801|Clostridia	G	C-terminal of Glycosyl hydrolases family 43	-	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	Dockerin_1,GH43_C,Glyco_hydro_43,Laminin_G_3
PNCOCPKN_01717	622312.ROSEINA2194_00234	2.21e-137	399.0	COG0042@1|root,COG0042@2|Bacteria,1TRJM@1239|Firmicutes,247R5@186801|Clostridia	186801|Clostridia	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
PNCOCPKN_01718	903814.ELI_1175	2.33e-51	203.0	COG3209@1|root,COG3209@2|Bacteria,1UK8Y@1239|Firmicutes,24M4J@186801|Clostridia,25XIP@186806|Eubacteriaceae	186801|Clostridia	M	Listeria-Bacteroides repeat domain (List_Bact_rpt)	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,Flg_new,LRR_5
PNCOCPKN_01719	658655.HMPREF0988_00838	0.0	1033.0	COG0507@1|root,COG1196@1|root,COG0507@2|Bacteria,COG1196@2|Bacteria,1TPU3@1239|Firmicutes,248HY@186801|Clostridia,27J7R@186928|unclassified Lachnospiraceae	186801|Clostridia	D	MobA/MobL family	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
PNCOCPKN_01720	585394.RHOM_01825	2.3e-124	354.0	COG0645@1|root,COG0645@2|Bacteria,1TSSD@1239|Firmicutes,24BDR@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18
PNCOCPKN_01721	585394.RHOM_01755	0.0	939.0	COG0488@1|root,COG0488@2|Bacteria,1TNYS@1239|Firmicutes,248D6@186801|Clostridia	186801|Clostridia	L	ABC transporter	expZ	-	-	ko:K19350	ko02010,map02010	-	-	-	ko00000,ko00001,ko01504,ko02000	3.A.1.121	-	-	ABC_tran
PNCOCPKN_01722	585394.RHOM_01750	1.72e-59	184.0	2B26K@1|root,31UPX@2|Bacteria,1V93Z@1239|Firmicutes,24JA0@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3847
PNCOCPKN_01723	445972.ANACOL_03121	2.97e-76	227.0	COG1349@1|root,COG1349@2|Bacteria,1V4EI@1239|Firmicutes,24HRM@186801|Clostridia,3WJ28@541000|Ruminococcaceae	186801|Clostridia	K	DeoR-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_DeoR
PNCOCPKN_01724	445972.ANACOL_03121	6.16e-05	43.1	COG1349@1|root,COG1349@2|Bacteria,1V4EI@1239|Firmicutes,24HRM@186801|Clostridia,3WJ28@541000|Ruminococcaceae	186801|Clostridia	K	DeoR-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_DeoR
PNCOCPKN_01725	622312.ROSEINA2194_02964	1.53e-39	130.0	2CBNR@1|root,32T16@2|Bacteria,1VA97@1239|Firmicutes,24NAW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01726	622312.ROSEINA2194_02965	2.86e-187	522.0	COG1396@1|root,COG1396@2|Bacteria,1TT2N@1239|Firmicutes,2488F@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19
PNCOCPKN_01727	622312.ROSEINA2194_02966	3.79e-121	345.0	COG0617@1|root,COG0617@2|Bacteria,1V1W2@1239|Firmicutes,24FII@186801|Clostridia	186801|Clostridia	J	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Aminoglyc_resit
PNCOCPKN_01728	622312.ROSEINA2194_02967	4.53e-88	258.0	2C5R4@1|root,2ZBQ6@2|Bacteria,1V1T6@1239|Firmicutes,24GMD@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
PNCOCPKN_01729	622312.ROSEINA2194_02968	2.04e-58	181.0	COG3655@1|root,COG3655@2|Bacteria,1V27G@1239|Firmicutes,24I0W@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
PNCOCPKN_01730	411483.FAEPRAA2165_00596	7.63e-29	103.0	2CDEH@1|root,330HN@2|Bacteria,1VG5T@1239|Firmicutes,24RUP@186801|Clostridia,3WRWB@541000|Ruminococcaceae	186801|Clostridia	S	Maff2 family	-	-	-	-	-	-	-	-	-	-	-	-	Maff2
PNCOCPKN_01731	1123263.AUKY01000003_gene302	8.98e-86	253.0	COG1396@1|root,COG1396@2|Bacteria,1V1JY@1239|Firmicutes,3VRXI@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PNCOCPKN_01732	552398.HMPREF0866_02815	3.08e-68	206.0	2DH9M@1|root,32U8W@2|Bacteria,1VB4S@1239|Firmicutes,24NUA@186801|Clostridia,3WMRE@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01733	552398.HMPREF0866_02816	0.0	1143.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia,3WGPS@541000|Ruminococcaceae	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf,TraG-D_C
PNCOCPKN_01734	1123263.AUKY01000003_gene305	6.05e-103	298.0	28I1B@1|root,2Z860@2|Bacteria,1TT6W@1239|Firmicutes,3VQTZ@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Protein of unknown function (DUF3801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3801
PNCOCPKN_01735	1123263.AUKY01000003_gene306	4.56e-70	211.0	2B1PF@1|root,2ZYHN@2|Bacteria,1V614@1239|Firmicutes,3VRD5@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01736	552398.HMPREF0866_02819	9.09e-149	419.0	COG4734@1|root,COG4734@2|Bacteria,1U2IB@1239|Firmicutes,24F5P@186801|Clostridia,3WMS6@541000|Ruminococcaceae	186801|Clostridia	S	DpnD/PcfM-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3846,DpnD-PcfM
PNCOCPKN_01737	1203606.HMPREF1526_01679	5.38e-63	198.0	2EGDR@1|root,33A5M@2|Bacteria,1VKA1@1239|Firmicutes,24UXY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01738	1123263.AUKY01000003_gene310	3.47e-214	592.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,3VQ3M@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
PNCOCPKN_01739	552398.HMPREF0866_02822	4.27e-187	521.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,247R1@186801|Clostridia,3WH20@541000|Ruminococcaceae	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain protein	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
PNCOCPKN_01740	626939.HMPREF9443_02158	4.43e-222	612.0	2DBC6@1|root,2Z8BZ@2|Bacteria,1TQXM@1239|Firmicutes	1239|Firmicutes	S	Replication initiator protein A	-	-	-	-	-	-	-	-	-	-	-	-	RepA_N
PNCOCPKN_01742	1121115.AXVN01000199_gene606	6.17e-243	668.0	COG3177@1|root,COG3177@2|Bacteria,1TQMC@1239|Firmicutes,248JU@186801|Clostridia,3XYYW@572511|Blautia	186801|Clostridia	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
PNCOCPKN_01743	411459.RUMOBE_02158	8.98e-18	82.4	29YMG@1|root,30KGY@2|Bacteria,1V4T3@1239|Firmicutes,24I7T@186801|Clostridia,3Y0BR@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
PNCOCPKN_01744	585394.RHOM_16850	5.1e-146	418.0	28J5A@1|root,2Z916@2|Bacteria,1TSGX@1239|Firmicutes,24AZU@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3881
PNCOCPKN_01745	585394.RHOM_16855	1.98e-143	416.0	COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,248S5@186801|Clostridia	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
PNCOCPKN_01746	585394.RHOM_16860	4.28e-62	196.0	COG1196@1|root,COG1196@2|Bacteria,1VAV4@1239|Firmicutes,24NPU@186801|Clostridia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
PNCOCPKN_01747	585394.RHOM_16865	6.14e-152	434.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
PNCOCPKN_01748	585394.RHOM_16870	7.63e-168	470.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
PNCOCPKN_01749	585394.RHOM_16875	7.92e-109	318.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,24FZX@186801|Clostridia	186801|Clostridia	K	response regulator receiver	degU	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
PNCOCPKN_01750	585394.RHOM_16880	1.56e-109	329.0	COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia	186801|Clostridia	T	Histidine kinase	degS	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegS,HATPase_c,HisKA_3
PNCOCPKN_01751	585394.RHOM_16885	2.74e-155	444.0	COG0596@1|root,COG0596@2|Bacteria,1TR3M@1239|Firmicutes,24DR9@186801|Clostridia	186801|Clostridia	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
PNCOCPKN_01752	585394.RHOM_16890	2.79e-127	367.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia	186801|Clostridia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
PNCOCPKN_01753	622312.ROSEINA2194_03228	0.0	1118.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,247U2@186801|Clostridia	186801|Clostridia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
PNCOCPKN_01754	622312.ROSEINA2194_03229	5.01e-273	753.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,248A9@186801|Clostridia	186801|Clostridia	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
PNCOCPKN_01755	622312.ROSEINA2194_03230	1.05e-118	342.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia	186801|Clostridia	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
PNCOCPKN_01756	585394.RHOM_16915	2.03e-218	613.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia	186801|Clostridia	U	Membrane protein insertase, YidC Oxa1 family	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
PNCOCPKN_01757	585394.RHOM_16925	3.33e-65	199.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,24QK5@186801|Clostridia	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
PNCOCPKN_01758	585394.RHOM_16930	3.25e-20	80.9	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,24UGN@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
PNCOCPKN_01759	622312.ROSEINA2194_03235	9.39e-296	810.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
PNCOCPKN_01760	585394.RHOM_00010	3.22e-248	683.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,248EG@186801|Clostridia	186801|Clostridia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
PNCOCPKN_01761	585394.RHOM_00015	1.54e-34	119.0	COG2501@1|root,COG2501@2|Bacteria	2|Bacteria	S	S4 domain	yaaA	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
PNCOCPKN_01762	622312.ROSEINA2194_03238	3.05e-214	597.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
PNCOCPKN_01763	585394.RHOM_00025	0.0	1207.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
PNCOCPKN_01764	585394.RHOM_00030	0.0	1509.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
PNCOCPKN_01765	537007.BLAHAN_05724	7.86e-157	451.0	COG3550@1|root,COG3550@2|Bacteria,1UYFT@1239|Firmicutes,24C8G@186801|Clostridia,3Y2EV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01767	1280692.AUJL01000002_gene2728	2.92e-88	288.0	COG1132@1|root,COG1132@2|Bacteria,1V2WX@1239|Firmicutes,24GV7@186801|Clostridia,36R7T@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
PNCOCPKN_01768	1123075.AUDP01000012_gene3562	8.46e-53	171.0	COG3279@1|root,COG3279@2|Bacteria,1VEPW@1239|Firmicutes,24K2U@186801|Clostridia	186801|Clostridia	K	LytTr DNA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
PNCOCPKN_01769	742740.HMPREF9474_01564	7.2e-53	171.0	2AH77@1|root,317H3@2|Bacteria,1V6I2@1239|Firmicutes,24KDW@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3021)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3021
PNCOCPKN_01770	658086.HMPREF0994_06595	0.0	1188.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,27JWP@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	CBM_6,Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
PNCOCPKN_01771	585394.RHOM_00040	1.12e-111	331.0	COG5495@1|root,COG5495@2|Bacteria,1UZZU@1239|Firmicutes,249YF@186801|Clostridia	186801|Clostridia	S	NADP oxidoreductase coenzyme F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
PNCOCPKN_01772	585394.RHOM_00045	6.66e-175	490.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
PNCOCPKN_01773	585394.RHOM_00050	3.49e-171	481.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
PNCOCPKN_01774	585394.RHOM_00055	1.39e-68	209.0	COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,24JVN@186801|Clostridia	186801|Clostridia	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
PNCOCPKN_01775	622312.ROSEINA2194_03241	9.97e-127	374.0	COG0840@1|root,COG4905@1|root,COG0840@2|Bacteria,COG4905@2|Bacteria,1V2HX@1239|Firmicutes,24B3D@186801|Clostridia	186801|Clostridia	D	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
PNCOCPKN_01776	622312.ROSEINA2194_03242	3.22e-169	476.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia	186801|Clostridia	C	Fe-S type, tartrate fumarate subfamily, alpha	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
PNCOCPKN_01777	622312.ROSEINA2194_03243	3.18e-119	342.0	COG1838@1|root,COG1838@2|Bacteria,1V1CP@1239|Firmicutes,24FRK@186801|Clostridia	186801|Clostridia	C	Fe-S type, tartrate fumarate subfamily, beta	fumB	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
PNCOCPKN_01779	585394.RHOM_00105	9.32e-179	505.0	COG0673@1|root,COG0673@2|Bacteria,1TPT5@1239|Firmicutes,248MV@186801|Clostridia	186801|Clostridia	E	Oxidoreductase NAD-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
PNCOCPKN_01781	585394.RHOM_12765	1.82e-77	238.0	2E401@1|root,32YWY@2|Bacteria,1V9X1@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01782	622312.ROSEINA2194_01509	2.79e-283	790.0	COG0366@1|root,COG0366@2|Bacteria,1TSEA@1239|Firmicutes,248HJ@186801|Clostridia	186801|Clostridia	G	Alpha amylase catalytic	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459
PNCOCPKN_01784	622312.ROSEINA2194_01508	1.62e-177	498.0	COG3833@1|root,COG3833@2|Bacteria,1TRB7@1239|Firmicutes,248A7@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
PNCOCPKN_01785	622312.ROSEINA2194_01507	2.3e-295	810.0	COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,247MA@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
PNCOCPKN_01786	622312.ROSEINA2194_01506	3.61e-242	674.0	COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia	186801|Clostridia	G	ABC transporter, solute-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
PNCOCPKN_01787	622312.ROSEINA2194_01505	1.64e-298	823.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia	186801|Clostridia	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
PNCOCPKN_01788	622312.ROSEINA2194_01504	7.44e-216	604.0	COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,24825@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	5.1.1.1	ko:K01775,ko:K02529	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011,ko03000	-	-	-	LacI,Peripla_BP_3
PNCOCPKN_01789	478749.BRYFOR_08059	2.24e-120	358.0	COG0477@1|root,COG2814@2|Bacteria,1TZWA@1239|Firmicutes,24C48@186801|Clostridia	186801|Clostridia	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
PNCOCPKN_01790	411459.RUMOBE_00652	0.0	1210.0	COG1961@1|root,COG3505@1|root,COG1961@2|Bacteria,COG3505@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3XYWF@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,T4SS-DNA_transf,Zn_ribbon_recom
PNCOCPKN_01791	1203606.HMPREF1526_01066	7.27e-73	219.0	2C5R4@1|root,30S72@2|Bacteria,1V578@1239|Firmicutes,24IJT@186801|Clostridia,36K3I@31979|Clostridiaceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
PNCOCPKN_01793	411483.FAEPRAA2165_00585	2.02e-79	241.0	28HZW@1|root,2Z84T@2|Bacteria,1UGDT@1239|Firmicutes,24FA4@186801|Clostridia,3WH5Z@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01794	1297617.JPJD01000080_gene1400	1.32e-66	203.0	292P2@1|root,2ZQ6W@2|Bacteria,1V4YF@1239|Firmicutes,24I6C@186801|Clostridia,26B4M@186813|unclassified Clostridiales	186801|Clostridia	S	Protein of unknown function (DUF3847)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3847
PNCOCPKN_01795	658086.HMPREF0994_06813	0.0	967.0	COG1196@1|root,COG1196@2|Bacteria,1TPU3@1239|Firmicutes,248HY@186801|Clostridia,27KST@186928|unclassified Lachnospiraceae	186801|Clostridia	D	MobA/MobL family	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
PNCOCPKN_01796	411473.RUMCAL_01422	0.0	1233.0	COG0358@1|root,COG3598@1|root,COG0358@2|Bacteria,COG3598@2|Bacteria,1TQKP@1239|Firmicutes,247WJ@186801|Clostridia,3WSPC@541000|Ruminococcaceae	186801|Clostridia	L	Protein of unknown function (DUF3991)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,DUF3991,Toprim_2
PNCOCPKN_01797	478749.BRYFOR_08059	1.07e-42	155.0	COG0477@1|root,COG2814@2|Bacteria,1TZWA@1239|Firmicutes,24C48@186801|Clostridia	186801|Clostridia	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
PNCOCPKN_01798	478749.BRYFOR_08058	2.25e-96	303.0	COG1396@1|root,COG1396@2|Bacteria,1VBK2@1239|Firmicutes,24N6F@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,TPR_8
PNCOCPKN_01799	585394.RHOM_01250	1.71e-161	468.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
PNCOCPKN_01800	585394.RHOM_02150	3.86e-81	242.0	COG1846@1|root,COG1846@2|Bacteria,1V6G0@1239|Firmicutes,24K11@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	ohrR	-	-	-	-	-	-	-	-	-	-	-	MarR
PNCOCPKN_01801	483218.BACPEC_02964	1.01e-36	127.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,269QT@186813|unclassified Clostridiales	186801|Clostridia	O	Thioredoxin-like domain	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
PNCOCPKN_01802	585394.RHOM_02135	8.13e-137	395.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
PNCOCPKN_01803	622312.ROSEINA2194_00484	7.95e-206	604.0	COG0369@1|root,COG0534@1|root,COG0534@2|Bacteria,COG1151@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PNCOCPKN_01804	478749.BRYFOR_05176	3.04e-222	625.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PNCOCPKN_01805	585394.RHOM_00905	1.58e-65	200.0	COG2315@1|root,COG2315@2|Bacteria,1VVT6@1239|Firmicutes,25EAU@186801|Clostridia	186801|Clostridia	L	6-O-methylguanine DNA methyltransferase, DNA binding domain protein	ogt	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1,YjbR
PNCOCPKN_01807	622312.ROSEINA2194_01812	8.6e-257	704.0	29Z45@1|root,30M1S@2|Bacteria,1V5Q9@1239|Firmicutes,24J6X@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01808	622312.ROSEINA2194_01813	1.11e-214	594.0	COG5464@1|root,COG5464@2|Bacteria,1UA0N@1239|Firmicutes,247X9@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
PNCOCPKN_01809	622312.ROSEINA2194_01814	4.87e-127	362.0	2DTU4@1|root,33MMZ@2|Bacteria,1VNW0@1239|Firmicutes,24X1J@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01810	411473.RUMCAL_02067	9.12e-34	125.0	COG1196@1|root,COG1196@2|Bacteria,1UQCD@1239|Firmicutes,24AY9@186801|Clostridia,3WSPG@541000|Ruminococcaceae	186801|Clostridia	D	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
PNCOCPKN_01811	1121296.JONJ01000012_gene368	8.03e-38	133.0	2DRW8@1|root,32URU@2|Bacteria,1VA9A@1239|Firmicutes,24QD5@186801|Clostridia,223AQ@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01812	411473.RUMCAL_02065	0.0	888.0	COG3378@1|root,COG3378@2|Bacteria,1TSGZ@1239|Firmicutes,24CI8@186801|Clostridia,3WHNR@541000|Ruminococcaceae	186801|Clostridia	S	Phage plasmid primase, P4 family	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	D5_N,Pox_D5
PNCOCPKN_01813	1519439.JPJG01000071_gene1528	1.15e-143	405.0	COG0358@1|root,COG0358@2|Bacteria,1UXWQ@1239|Firmicutes,25MCW@186801|Clostridia,2N7ZX@216572|Oscillospiraceae	186801|Clostridia	L	CHC2 zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHC2
PNCOCPKN_01814	483218.BACPEC_00285	6.75e-247	680.0	28ICW@1|root,2Z8F5@2|Bacteria,1TSMN@1239|Firmicutes,24BRU@186801|Clostridia,269YH@186813|unclassified Clostridiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01815	293826.Amet_2266	1.75e-36	137.0	2EJ9G@1|root,33D0N@2|Bacteria,1VPR8@1239|Firmicutes,24Z01@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01816	411473.RUMCAL_02060	1.11e-281	769.0	COG1191@1|root,COG1191@2|Bacteria,1U0Q7@1239|Firmicutes,249NN@186801|Clostridia,3WNXR@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01817	483218.BACPEC_00282	4.2e-155	436.0	COG0745@1|root,COG0745@2|Bacteria,1TSNV@1239|Firmicutes,2493A@186801|Clostridia,268X2@186813|unclassified Clostridiales	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PNCOCPKN_01818	483218.BACPEC_00281	1.74e-198	551.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia,268Z5@186813|unclassified Clostridiales	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PNCOCPKN_01819	483218.BACPEC_00280	2.9e-150	423.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,2689T@186813|unclassified Clostridiales	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PNCOCPKN_01820	483218.BACPEC_00279	0.0	1660.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,268JZ@186813|unclassified Clostridiales	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
PNCOCPKN_01821	411473.RUMCAL_02055	5.28e-53	166.0	2CZEX@1|root,32T68@2|Bacteria,1VB18@1239|Firmicutes,24MZP@186801|Clostridia,3WPUQ@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01822	1280698.AUJS01000056_gene1438	0.0	1224.0	COG1961@1|root,COG2265@1|root,COG1961@2|Bacteria,COG2265@2|Bacteria,1TPUG@1239|Firmicutes,25B03@186801|Clostridia,27WXT@189330|Dorea	186801|Clostridia	L	Recombinase zinc beta ribbon domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
PNCOCPKN_01823	1121115.AXVN01000119_gene3272	5.43e-35	119.0	2BJ3C@1|root,32DC9@2|Bacteria,1V88B@1239|Firmicutes,25A9I@186801|Clostridia,3Y20E@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01824	1121115.AXVN01000119_gene3273	4.04e-142	401.0	COG0454@1|root,COG0456@2|Bacteria,1UHW4@1239|Firmicutes,24I24@186801|Clostridia,3Y1FU@572511|Blautia	186801|Clostridia	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01825	411463.EUBVEN_00921	3.94e-21	83.2	2E3ZC@1|root,32YWA@2|Bacteria,1VHZW@1239|Firmicutes,24SMN@186801|Clostridia,25XQP@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01826	585394.RHOM_13325	0.0	1413.0	COG0457@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3903@2|Bacteria,1TY16@1239|Firmicutes,24A3H@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12
PNCOCPKN_01827	411469.EUBHAL_02118	8.46e-206	569.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,25VEQ@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PNCOCPKN_01828	457412.RSAG_01813	2.5e-153	431.0	2B7SS@1|root,320Z4@2|Bacteria,1V805@1239|Firmicutes,24IU3@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01829	457412.RSAG_01814	3.95e-251	689.0	COG1277@1|root,COG1277@2|Bacteria,1UYRU@1239|Firmicutes,24A07@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
PNCOCPKN_01830	457412.RSAG_01815	7.68e-274	750.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1TRZX@1239|Firmicutes,249AI@186801|Clostridia,3WIVN@541000|Ruminococcaceae	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K20487	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
PNCOCPKN_01831	411469.EUBHAL_02113	6.76e-159	446.0	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,248WX@186801|Clostridia,25YCG@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
PNCOCPKN_01832	411469.EUBHAL_02114	1.57e-219	607.0	2DB8G@1|root,2Z7RT@2|Bacteria,1US26@1239|Firmicutes,24B9G@186801|Clostridia,25ZTY@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	ko:K18640	-	-	-	-	ko00000,ko04812	-	-	-	StbA
PNCOCPKN_01833	411469.EUBHAL_02112	4.68e-82	243.0	28ZZK@1|root,2ZMPX@2|Bacteria,1V41I@1239|Firmicutes,24RFQ@186801|Clostridia,25WGW@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01834	585394.RHOM_13365	1.33e-167	468.0	COG1349@1|root,COG1349@2|Bacteria,1TSUV@1239|Firmicutes,24CQC@186801|Clostridia	186801|Clostridia	GK	Replication initiator protein A (RepA) N-terminus	repA	-	-	-	-	-	-	-	-	-	-	-	RepA_N
PNCOCPKN_01835	411469.EUBHAL_02110	2.53e-83	253.0	COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,248F0@186801|Clostridia,25VAQ@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
PNCOCPKN_01836	457412.RSAG_04584	2.33e-29	107.0	COG3547@1|root,COG3547@2|Bacteria,1TQP6@1239|Firmicutes,248VD@186801|Clostridia	186801|Clostridia	L	transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
PNCOCPKN_01837	622312.ROSEINA2194_04022	1.82e-186	523.0	COG3385@1|root,COG3385@2|Bacteria,1TSH6@1239|Firmicutes,24A21@186801|Clostridia	186801|Clostridia	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
PNCOCPKN_01838	622312.ROSEINA2194_03203	1.39e-232	638.0	COG1680@1|root,COG1680@2|Bacteria,1UUHI@1239|Firmicutes,24AX5@186801|Clostridia	186801|Clostridia	V	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
PNCOCPKN_01839	622312.ROSEINA2194_03202	5.49e-261	713.0	COG4733@1|root,COG4733@2|Bacteria,1UI04@1239|Firmicutes,25E8W@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
PNCOCPKN_01841	585394.RHOM_07300	0.0	981.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,248RK@186801|Clostridia	186801|Clostridia	K	Fibronectin-binding protein	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
PNCOCPKN_01842	665956.HMPREF1032_02998	3.76e-60	199.0	COG1266@1|root,COG1266@2|Bacteria,1USCY@1239|Firmicutes,24F5M@186801|Clostridia,3WMPA@541000|Ruminococcaceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
PNCOCPKN_01843	585394.RHOM_07295	9.78e-260	713.0	COG4225@1|root,COG4225@2|Bacteria,1TRJ7@1239|Firmicutes,24806@186801|Clostridia	186801|Clostridia	S	Glycosyl Hydrolase Family 88	-	-	3.2.1.172	ko:K15532	-	-	-	-	ko00000,ko01000	-	GH105	-	Glyco_hydro_88
PNCOCPKN_01844	585394.RHOM_07275	7.8e-38	127.0	2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,24QPW@186801|Clostridia	186801|Clostridia	S	'small, acid-soluble spore protein	sasP	-	-	ko:K06421	-	-	-	-	ko00000	-	-	-	SASP
PNCOCPKN_01845	585394.RHOM_07270	0.0	998.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
PNCOCPKN_01846	585394.RHOM_07265	0.0	900.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,247XI@186801|Clostridia	186801|Clostridia	S	DAK2 domain fusion protein YloV	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
PNCOCPKN_01847	585394.RHOM_07260	2.12e-72	218.0	COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,24JIA@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
PNCOCPKN_01848	1280688.AUJB01000008_gene1258	2.69e-35	120.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,3NHEH@46205|Pseudobutyrivibrio	186801|Clostridia	J	Ribosomal L28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
PNCOCPKN_01849	180332.JTGN01000010_gene4424	1.48e-58	204.0	COG5492@1|root,COG5492@2|Bacteria,1UINF@1239|Firmicutes,25EP2@186801|Clostridia	186801|Clostridia	N	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
PNCOCPKN_01850	585394.RHOM_08170	1.64e-165	467.0	COG1082@1|root,COG1082@2|Bacteria,1U81K@1239|Firmicutes,2492P@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
PNCOCPKN_01851	585394.RHOM_08175	1.65e-267	744.0	COG5434@1|root,COG5434@2|Bacteria,1TQQW@1239|Firmicutes,24A0R@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
PNCOCPKN_01853	483218.BACPEC_01722	2.45e-275	774.0	COG0666@1|root,COG3507@1|root,COG0666@2|Bacteria,COG3507@2|Bacteria,1TP5K@1239|Firmicutes,247R2@186801|Clostridia,26AET@186813|unclassified Clostridiales	186801|Clostridia	G	Glycosyl hydrolases family 43	-	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	Ank_2,Ank_4,Glyco_hydro_43
PNCOCPKN_01854	515622.bpr_I1585	1.93e-209	600.0	COG3507@1|root,COG3507@2|Bacteria,1UDW2@1239|Firmicutes,24A81@186801|Clostridia,4BYGR@830|Butyrivibrio	186801|Clostridia	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
PNCOCPKN_01855	1280668.ATVT01000001_gene794	6.9e-94	281.0	COG2755@1|root,COG2755@2|Bacteria,1V2SC@1239|Firmicutes,24H62@186801|Clostridia,4BWRN@830|Butyrivibrio	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
PNCOCPKN_01856	1298920.KI911353_gene1189	1.36e-146	419.0	COG0395@1|root,COG0395@2|Bacteria,1TSX2@1239|Firmicutes,24891@186801|Clostridia,222N7@1506553|Lachnoclostridium	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K17320	ko02010,map02010	M00207,M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
PNCOCPKN_01857	1304866.K413DRAFT_2463	4.98e-146	421.0	COG4209@1|root,COG4209@2|Bacteria,1TP33@1239|Firmicutes,247UA@186801|Clostridia,36GXV@31979|Clostridiaceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
PNCOCPKN_01858	1304866.K413DRAFT_2462	8.32e-230	650.0	COG1653@1|root,COG1653@2|Bacteria,1TW09@1239|Firmicutes,24BZW@186801|Clostridia,36G3C@31979|Clostridiaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
PNCOCPKN_01859	1449050.JNLE01000003_gene3046	5.16e-90	307.0	COG2207@1|root,COG2207@2|Bacteria,1UZQJ@1239|Firmicutes,24GN0@186801|Clostridia,36HGH@31979|Clostridiaceae	186801|Clostridia	K	transcriptional regulator, arac family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
PNCOCPKN_01860	1235793.C809_01107	4.63e-203	578.0	COG1680@1|root,COG1680@2|Bacteria,1TSXS@1239|Firmicutes,24H20@186801|Clostridia	186801|Clostridia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
PNCOCPKN_01861	585394.RHOM_04075	9.67e-177	494.0	COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,24903@186801|Clostridia	186801|Clostridia	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
PNCOCPKN_01862	585394.RHOM_08205	2.51e-305	838.0	COG2721@1|root,COG2721@2|Bacteria,1TPTX@1239|Firmicutes,24AEC@186801|Clostridia	186801|Clostridia	G	D-galactarate dehydratase Altronate hydrolase	uxaA	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
PNCOCPKN_01863	585394.RHOM_08210	0.0	873.0	COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,248J5@186801|Clostridia	186801|Clostridia	G	Mannitol dehydrogenase	-	-	1.1.1.58	ko:K00041	ko00040,ko01100,map00040,map01100	M00631	R02555	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
PNCOCPKN_01864	585394.RHOM_08220	8.53e-197	550.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	ccpA	-	-	ko:K02529,ko:K03487	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
PNCOCPKN_01865	585394.RHOM_08225	0.0	883.0	COG1904@1|root,COG1904@2|Bacteria,1TRI0@1239|Firmicutes,248C0@186801|Clostridia	186801|Clostridia	G	glucuronate isomerase	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
PNCOCPKN_01866	585394.RHOM_08230	5.51e-205	567.0	COG3717@1|root,COG3717@2|Bacteria,1TP4X@1239|Firmicutes,24A00@186801|Clostridia	186801|Clostridia	G	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate	kduI	-	5.3.1.17	ko:K01815	ko00040,map00040	-	R04383	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
PNCOCPKN_01867	585394.RHOM_08235	3.84e-145	409.0	COG0698@1|root,COG0698@2|Bacteria,1TQQJ@1239|Firmicutes,249IB@186801|Clostridia	186801|Clostridia	G	Ribose Galactose Isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3666,LacAB_rpiB
PNCOCPKN_01868	1235798.C817_02525	1.12e-08	52.0	2ERI6@1|root,33J3P@2|Bacteria,1VMBI@1239|Firmicutes,24VNP@186801|Clostridia,27VXK@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01869	585394.RHOM_08245	1.01e-81	244.0	COG3874@1|root,COG3874@2|Bacteria,1V99U@1239|Firmicutes,24K00@186801|Clostridia	186801|Clostridia	S	Sporulation protein YtfJ	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
PNCOCPKN_01870	622312.ROSEINA2194_01756	4.41e-43	157.0	2E3Z2@1|root,32YW0@2|Bacteria,1VGF4@1239|Firmicutes,24PIY@186801|Clostridia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	DUF2953
PNCOCPKN_01871	622312.ROSEINA2194_01757	4.77e-52	166.0	2CSSR@1|root,32SRT@2|Bacteria,1VKAJ@1239|Firmicutes,24N3Y@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01872	585394.RHOM_08260	1.99e-94	276.0	COG1051@1|root,COG1051@2|Bacteria,1V4E6@1239|Firmicutes,24HPT@186801|Clostridia	186801|Clostridia	F	Belongs to the Nudix hydrolase family	apfA	-	-	-	-	-	-	-	-	-	-	-	NUDIX
PNCOCPKN_01873	585394.RHOM_08265	1.45e-237	667.0	COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,2486R@186801|Clostridia	186801|Clostridia	M	Penicillin-binding Protein	pbpA2	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
PNCOCPKN_01874	585394.RHOM_08270	5.21e-225	632.0	COG0772@1|root,COG0772@2|Bacteria,1TQ82@1239|Firmicutes,248QS@186801|Clostridia	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FHA,FTSW_RODA_SPOVE
PNCOCPKN_01875	622312.ROSEINA2194_00527	2.18e-309	870.0	COG0826@1|root,COG0826@2|Bacteria,1TQS1@1239|Firmicutes,24909@186801|Clostridia	186801|Clostridia	O	peptidase U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
PNCOCPKN_01876	585394.RHOM_08280	5.98e-60	189.0	COG3027@1|root,COG3027@2|Bacteria,1V4E5@1239|Firmicutes,24HQR@186801|Clostridia	186801|Clostridia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
PNCOCPKN_01877	585394.RHOM_08285	1.75e-214	595.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
PNCOCPKN_01878	622312.ROSEINA2194_00524	1.33e-111	324.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
PNCOCPKN_01879	585394.RHOM_08295	1.51e-80	242.0	COG4769@1|root,COG4769@2|Bacteria,1V1M0@1239|Firmicutes,24MZC@186801|Clostridia	186801|Clostridia	S	Heptaprenyl diphosphate synthase component I	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	Hpre_diP_synt_I
PNCOCPKN_01880	585394.RHOM_08300	1.34e-41	140.0	COG5341@1|root,COG5341@2|Bacteria	2|Bacteria	S	NusG domain II	-	-	-	-	-	-	-	-	-	-	-	-	NusG_II
PNCOCPKN_01881	585394.RHOM_08305	2.48e-301	828.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
PNCOCPKN_01884	1536769.P40081_27475	4.58e-15	78.6	COG2856@1|root,COG2856@2|Bacteria,1VF46@1239|Firmicutes	1239|Firmicutes	E	Pfam:DUF955	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
PNCOCPKN_01885	1235802.C823_05603	8.05e-135	426.0	COG1040@1|root,COG1040@2|Bacteria,1UZTG@1239|Firmicutes,24CG1@186801|Clostridia,25Y2V@186806|Eubacteriaceae	186801|Clostridia	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01890	397287.C807_01799	1.26e-08	50.8	2BEY0@1|root,328PP@2|Bacteria,1UUMP@1239|Firmicutes,25766@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01893	622312.ROSEINA2194_03624	4.31e-312	853.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia	186801|Clostridia	L	Reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
PNCOCPKN_01896	411489.CLOL250_00366	1.11e-14	84.7	COG3210@1|root,COG4886@1|root,COG5492@1|root,COG3210@2|Bacteria,COG4886@2|Bacteria,COG5492@2|Bacteria,1TS8J@1239|Firmicutes,24A7I@186801|Clostridia,36HMP@31979|Clostridiaceae	186801|Clostridia	N	COG COG3291 FOG PKD repeat	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Flg_new,LRR_5,N_methyl,fn3
PNCOCPKN_01897	585394.RHOM_01040	2.34e-192	538.0	COG0317@1|root,COG0317@2|Bacteria,1TQW3@1239|Firmicutes,2483C@186801|Clostridia	186801|Clostridia	KT	PFAM Region found in RelA SpoT proteins	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
PNCOCPKN_01898	585394.RHOM_04925	4.15e-216	599.0	COG0232@1|root,COG0232@2|Bacteria,1TPEI@1239|Firmicutes,247Q1@186801|Clostridia	186801|Clostridia	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
PNCOCPKN_01899	622312.ROSEINA2194_03431	0.0	934.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
PNCOCPKN_01900	585394.RHOM_04935	2.13e-238	661.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
PNCOCPKN_01901	585394.RHOM_04940	1.48e-94	284.0	COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,24BJI@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	trmK	-	2.1.1.217	ko:K06967	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_18,TrmK
PNCOCPKN_01902	585394.RHOM_04945	0.0	896.0	COG0441@1|root,COG0572@1|root,COG0441@2|Bacteria,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,249IT@186801|Clostridia	186801|Clostridia	F	uridine kinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
PNCOCPKN_01903	622312.ROSEINA2194_03540	1.41e-54	174.0	COG4416@1|root,COG4416@2|Bacteria,1VEMD@1239|Firmicutes,24MRR@186801|Clostridia	186801|Clostridia	S	COG NOG18757 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01904	622312.ROSEINA2194_03539	2.9e-167	472.0	2CC4I@1|root,2Z8PZ@2|Bacteria,1TQTT@1239|Firmicutes,24AJ3@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01905	622312.ROSEINA2194_03538	2.51e-119	344.0	COG0484@1|root,COG0484@2|Bacteria,1V1GK@1239|Firmicutes,2494E@186801|Clostridia	186801|Clostridia	O	DnaJ domain protein	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,TPR_2
PNCOCPKN_01906	585394.RHOM_10050	5.15e-90	265.0	COG1781@1|root,COG1781@2|Bacteria,1V6U9@1239|Firmicutes,24JJU@186801|Clostridia	186801|Clostridia	F	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
PNCOCPKN_01907	585394.RHOM_10045	1.9e-200	557.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N,PyrI_C
PNCOCPKN_01908	585394.RHOM_10035	2.14e-65	201.0	COG4905@1|root,COG4905@2|Bacteria,1VAQJ@1239|Firmicutes,24K5I@186801|Clostridia	186801|Clostridia	S	Putative ABC-transporter type IV	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
PNCOCPKN_01909	585394.RHOM_10030	1.11e-219	624.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
PNCOCPKN_01910	585394.RHOM_10025	0.0	1028.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
PNCOCPKN_01911	622312.ROSEINA2194_03530	6.49e-92	271.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,24JET@186801|Clostridia	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
PNCOCPKN_01912	585394.RHOM_10015	5.63e-178	501.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
PNCOCPKN_01913	622312.ROSEINA2194_03528	4.26e-143	406.0	COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,2490Y@186801|Clostridia	186801|Clostridia	S	zinc metallopeptidase	yugP	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
PNCOCPKN_01914	622312.ROSEINA2194_03527	4.6e-201	570.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia	186801|Clostridia	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
PNCOCPKN_01915	622312.ROSEINA2194_03526	1.26e-211	589.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
PNCOCPKN_01916	622312.ROSEINA2194_03525	2.75e-126	365.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia	186801|Clostridia	T	Phosphatase	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
PNCOCPKN_01917	585394.RHOM_09990	7.26e-285	803.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia	186801|Clostridia	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
PNCOCPKN_01918	585394.RHOM_09985	2.14e-162	460.0	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,248R5@186801|Clostridia	186801|Clostridia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
PNCOCPKN_01919	585394.RHOM_09980	3.28e-128	367.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia	186801|Clostridia	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
PNCOCPKN_01920	585394.RHOM_09975	7.81e-89	268.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia	186801|Clostridia	H	thiamine pyrophosphokinase	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
PNCOCPKN_01921	483218.BACPEC_02584	9.87e-27	100.0	COG3668@1|root,COG3668@2|Bacteria,1V9NW@1239|Firmicutes,24KYQ@186801|Clostridia,2697W@186813|unclassified Clostridiales	186801|Clostridia	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
PNCOCPKN_01922	585394.RHOM_05085	1.49e-251	691.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
PNCOCPKN_01923	585394.RHOM_05090	1.43e-43	142.0	COG1873@1|root,COG1873@2|Bacteria,1VEMT@1239|Firmicutes	1239|Firmicutes	S	sporulation protein, YlmC YmxH family	ylmC	-	-	-	-	-	-	-	-	-	-	-	PRC
PNCOCPKN_01924	585394.RHOM_05095	7.84e-101	292.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
PNCOCPKN_01925	585394.RHOM_05100	1.49e-31	115.0	2E9G7@1|root,333PE@2|Bacteria,1VHIP@1239|Firmicutes,24UC4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01926	585394.RHOM_05105	7.28e-101	294.0	COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,24KK7@186801|Clostridia	186801|Clostridia	F	HAD superfamily (Subfamily IIIA) phosphatase, TIGR01668	yqeG	-	-	ko:K07015	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase
PNCOCPKN_01927	585394.RHOM_05110	1.21e-94	276.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia	186801|Clostridia	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
PNCOCPKN_01928	622312.ROSEINA2194_01540	5.61e-127	361.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
PNCOCPKN_01929	585394.RHOM_13045	5.02e-276	776.0	COG1609@1|root,COG2199@1|root,COG1609@2|Bacteria,COG3706@2|Bacteria,1TSMK@1239|Firmicutes,24EJV@186801|Clostridia	186801|Clostridia	KT	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Peripla_BP_3
PNCOCPKN_01930	1235790.C805_02517	3.25e-151	464.0	COG4188@1|root,COG4188@2|Bacteria,1UGK7@1239|Firmicutes,24CXP@186801|Clostridia	186801|Clostridia	S	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase2
PNCOCPKN_01931	1235802.C823_03877	4.03e-184	526.0	COG2866@1|root,COG3409@1|root,COG2866@2|Bacteria,COG3409@2|Bacteria,1TP3K@1239|Firmicutes,249MT@186801|Clostridia,25WZ3@186806|Eubacteriaceae	186801|Clostridia	E	Zn_pept	-	-	3.4.19.11	ko:K01308	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	LysM,PG_binding_1,Peptidase_M14
PNCOCPKN_01932	411469.EUBHAL_02917	5.5e-142	410.0	COG0523@1|root,COG0523@2|Bacteria,1TQRE@1239|Firmicutes,24B0I@186801|Clostridia,25VJT@186806|Eubacteriaceae	186801|Clostridia	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
PNCOCPKN_01933	585394.RHOM_09385	1.69e-76	246.0	2DMDS@1|root,32QT4@2|Bacteria,1UINH@1239|Firmicutes,25EP3@186801|Clostridia	186801|Clostridia	S	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
PNCOCPKN_01934	622312.ROSEINA2194_00480	1.7e-204	578.0	COG3864@1|root,COG3864@2|Bacteria,1TSI1@1239|Firmicutes,248YT@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
PNCOCPKN_01935	1449050.JNLE01000003_gene1630	2.74e-43	160.0	COG3250@1|root,COG3250@2|Bacteria,1TU92@1239|Firmicutes,248WD@186801|Clostridia,36FQK@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
PNCOCPKN_01936	483218.BACPEC_02744	2.56e-227	632.0	COG1132@1|root,COG1132@2|Bacteria,1US0C@1239|Firmicutes,24EZJ@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
PNCOCPKN_01938	1392493.JIAB01000001_gene25	1.69e-30	117.0	29XCI@1|root,30J2B@2|Bacteria,1UKAD@1239|Firmicutes,24VP8@186801|Clostridia	186801|Clostridia	S	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
PNCOCPKN_01939	397290.C810_00859	1.33e-31	111.0	2CCMH@1|root,33C4S@2|Bacteria,1VNC0@1239|Firmicutes,24R5P@186801|Clostridia,27QF0@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
PNCOCPKN_01941	1514668.JOOA01000002_gene3358	1.86e-117	352.0	COG0699@1|root,COG0699@2|Bacteria,1U979@1239|Firmicutes,24UQD@186801|Clostridia	186801|Clostridia	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
PNCOCPKN_01945	1410632.JHWW01000013_gene228	8.33e-13	69.3	COG5492@1|root,COG5492@2|Bacteria,1V62C@1239|Firmicutes	1239|Firmicutes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Flg_new
PNCOCPKN_01947	97139.C824_05805	2.49e-169	479.0	28HEE@1|root,2Z7QU@2|Bacteria,1TVQR@1239|Firmicutes,248QB@186801|Clostridia,36HCK@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF932
PNCOCPKN_01949	1235792.C808_01094	3.19e-171	483.0	COG5377@1|root,COG5377@2|Bacteria,1TS2Y@1239|Firmicutes,249SB@186801|Clostridia,27KB5@186928|unclassified Lachnospiraceae	186801|Clostridia	L	YqaJ-like viral recombinase domain	-	-	-	-	-	-	-	-	-	-	-	-	YqaJ
PNCOCPKN_01950	1298920.KI911353_gene5322	1.23e-136	392.0	COG3723@1|root,COG3723@2|Bacteria,1UNDF@1239|Firmicutes,24CI5@186801|Clostridia,2218Y@1506553|Lachnoclostridium	186801|Clostridia	L	RecT family	recT	-	-	ko:K07455	-	-	-	-	ko00000,ko03400	-	-	-	RecT
PNCOCPKN_01951	1392493.JIAB01000001_gene44	5.02e-51	177.0	28PM6@1|root,2ZCAA@2|Bacteria,1V4NT@1239|Firmicutes,24HIP@186801|Clostridia,27MN9@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01952	622312.ROSEINA2194_01478	2.37e-203	588.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1,sCache_2
PNCOCPKN_01953	585394.RHOM_08575	0.0	907.0	COG0840@1|root,COG0840@2|Bacteria,1UYFA@1239|Firmicutes,24F3M@186801|Clostridia	186801|Clostridia	NT	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal,PilZ
PNCOCPKN_01954	585394.RHOM_02970	2.3e-41	138.0	2C1ED@1|root,33FE6@2|Bacteria,1VKWJ@1239|Firmicutes,24VDX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01955	1449050.JNLE01000005_gene4149	2.92e-164	491.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,36WU1@31979|Clostridiaceae	186801|Clostridia	E	Extracellular solute-binding protein, family 5	-	-	-	ko:K02035,ko:K15584	ko02010,ko02024,map02010,map02024	M00239,M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
PNCOCPKN_01956	592026.GCWU0000282_003030	1.44e-137	400.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	appB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
PNCOCPKN_01957	1449050.JNLE01000005_gene4147	1.73e-142	433.0	COG1173@1|root,COG5184@1|root,COG1173@2|Bacteria,COG5184@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,36E1E@31979|Clostridiaceae	186801|Clostridia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N,RCC1_2
PNCOCPKN_01958	1449050.JNLE01000005_gene4146	7.26e-206	573.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,36DZS@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
PNCOCPKN_01959	592026.GCWU0000282_003027	2.27e-205	586.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	appF	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
PNCOCPKN_01962	622312.ROSEINA2194_00691	2.47e-217	608.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia	186801|Clostridia	E	PFAM Extracellular ligand-binding receptor	braC	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PNCOCPKN_01963	585394.RHOM_03045	7.09e-179	501.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,2480A@186801|Clostridia	186801|Clostridia	E	Belongs to the binding-protein-dependent transport system permease family	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PNCOCPKN_01964	622312.ROSEINA2194_00693	7.84e-207	578.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,248WH@186801|Clostridia	186801|Clostridia	E	Belongs to the binding-protein-dependent transport system permease family	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PNCOCPKN_01965	622312.ROSEINA2194_00694	7.24e-163	457.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,2490B@186801|Clostridia	186801|Clostridia	E	Abc transporter	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PNCOCPKN_01966	622312.ROSEINA2194_00695	1.16e-151	428.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia	186801|Clostridia	E	Abc transporter	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PNCOCPKN_01967	585394.RHOM_03065	2.73e-122	351.0	COG1102@1|root,COG1102@2|Bacteria,1V1PJ@1239|Firmicutes,24GMN@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
PNCOCPKN_01968	585394.RHOM_03075	2.78e-193	545.0	COG1453@1|root,COG1453@2|Bacteria,1TQ5N@1239|Firmicutes,247SD@186801|Clostridia	186801|Clostridia	C	aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17,Fer4_9
PNCOCPKN_01969	397287.C807_00819	2.83e-108	317.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia,27KNA@186928|unclassified Lachnospiraceae	186801|Clostridia	P	TrkA-N domain	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
PNCOCPKN_01970	610130.Closa_2435	1.3e-177	511.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,21XK8@1506553|Lachnoclostridium	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
PNCOCPKN_01972	585394.RHOM_03130	1.03e-64	206.0	COG4728@1|root,COG4728@2|Bacteria,1VENJ@1239|Firmicutes,24SFD@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653
PNCOCPKN_01973	585394.RHOM_03135	9.08e-191	540.0	COG2263@1|root,COG2263@2|Bacteria,1TQUZ@1239|Firmicutes,248AM@186801|Clostridia	186801|Clostridia	J	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
PNCOCPKN_01974	585394.RHOM_03140	4.82e-88	260.0	COG2954@1|root,COG2954@2|Bacteria,1V7MS@1239|Firmicutes,24JER@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
PNCOCPKN_01975	585394.RHOM_03145	1.01e-102	300.0	COG0693@1|root,COG0693@2|Bacteria,1V3WB@1239|Firmicutes,24HGU@186801|Clostridia	186801|Clostridia	S	DJ-1 family	yajL	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
PNCOCPKN_01976	585394.RHOM_03215	3.17e-37	125.0	2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,24QPW@186801|Clostridia	186801|Clostridia	S	'small, acid-soluble spore protein	sasP	-	-	ko:K06421	-	-	-	-	ko00000	-	-	-	SASP
PNCOCPKN_01977	1256908.HMPREF0373_00285	2.54e-277	771.0	COG1672@1|root,COG1672@2|Bacteria,1TPQR@1239|Firmicutes,24AIK@186801|Clostridia,25YER@186806|Eubacteriaceae	186801|Clostridia	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,PDDEXK_3
PNCOCPKN_01978	457412.RSAG_03498	4.24e-146	420.0	COG3547@1|root,COG3547@2|Bacteria,1TPSP@1239|Firmicutes,24AH4@186801|Clostridia,3WGYW@541000|Ruminococcaceae	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
PNCOCPKN_01979	483218.BACPEC_02571	2.52e-156	445.0	28MNT@1|root,2ZAY9@2|Bacteria,1UJWE@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01980	483218.BACPEC_02572	6.6e-158	443.0	COG2088@1|root,COG2088@2|Bacteria,1V5IZ@1239|Firmicutes,24GMU@186801|Clostridia,26C5K@186813|unclassified Clostridiales	186801|Clostridia	D	SpoVG	-	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
PNCOCPKN_01981	483218.BACPEC_02573	8.31e-77	230.0	2DC0U@1|root,2ZC9U@2|Bacteria,1V2M2@1239|Firmicutes,24GUR@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01982	483218.BACPEC_02574	1.71e-57	180.0	COG3764@1|root,COG3764@2|Bacteria,1V3KS@1239|Firmicutes,24IPY@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	-
PNCOCPKN_01983	511680.BUTYVIB_01368	0.0	4862.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,1TPQA@1239|Firmicutes,2491X@186801|Clostridia,4BYXT@830|Butyrivibrio	186801|Clostridia	L	helicase C-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,N6_Mtase,ResIII,SNF2_N
PNCOCPKN_01984	511680.BUTYVIB_01369	1.22e-77	231.0	2A9KM@1|root,2ZG60@2|Bacteria,1V36P@1239|Firmicutes,24GPF@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01985	483218.BACPEC_02579	2.24e-41	136.0	2F899@1|root,340NF@2|Bacteria,1VWPV@1239|Firmicutes,251GE@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DpnD-PcfM
PNCOCPKN_01986	511680.BUTYVIB_01371	1.48e-218	602.0	28IAI@1|root,2Z8D4@2|Bacteria,1V027@1239|Firmicutes,24B3S@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01987	585394.RHOM_16475	0.0	988.0	COG0791@1|root,COG0791@2|Bacteria,1UYV9@1239|Firmicutes	1239|Firmicutes	M	NlpC P60 family protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
PNCOCPKN_01988	483218.BACPEC_02582	0.0	1563.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,248ND@186801|Clostridia,268HK@186813|unclassified Clostridiales	186801|Clostridia	U	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87
PNCOCPKN_01989	483218.BACPEC_02583	4.95e-56	175.0	COG2161@1|root,COG2161@2|Bacteria,1V336@1239|Firmicutes,24NWF@186801|Clostridia	186801|Clostridia	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
PNCOCPKN_01990	483218.BACPEC_02584	2.21e-72	217.0	COG3668@1|root,COG3668@2|Bacteria,1V9NW@1239|Firmicutes,24KYQ@186801|Clostridia,2697W@186813|unclassified Clostridiales	186801|Clostridia	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
PNCOCPKN_01991	483218.BACPEC_02585	8.76e-110	317.0	28XQJ@1|root,2ZJM8@2|Bacteria,1V2X9@1239|Firmicutes,24E6S@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PrgI
PNCOCPKN_01992	483218.BACPEC_02586	7.54e-99	286.0	28MPH@1|root,2ZAYS@2|Bacteria,1TT66@1239|Firmicutes,24FFZ@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4313
PNCOCPKN_01993	483218.BACPEC_02587	1.68e-191	532.0	2DB6V@1|root,2Z7IJ@2|Bacteria,1TRNS@1239|Firmicutes,24ANE@186801|Clostridia,267YD@186813|unclassified Clostridiales	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01994	511680.BUTYVIB_01379	2.16e-77	231.0	299KT@1|root,2ZWP8@2|Bacteria,1V5IJ@1239|Firmicutes,24N53@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01995	585394.RHOM_16520	0.0	1426.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia	186801|Clostridia	U	COG COG3505 Type IV secretory pathway, VirD4 components	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf,TraG-D_C
PNCOCPKN_01996	511680.BUTYVIB_01740	2.31e-258	709.0	2CF7U@1|root,2Z7U3@2|Bacteria,1UYHD@1239|Firmicutes,24C76@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3801
PNCOCPKN_01997	483218.BACPEC_02593	9.96e-85	250.0	2CJ59@1|root,2ZGJ1@2|Bacteria,1V30K@1239|Firmicutes,24H8I@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01998	483218.BACPEC_02594	4.82e-259	713.0	28M18@1|root,2ZAG5@2|Bacteria,1UBEC@1239|Firmicutes,24DSX@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_01999	585394.RHOM_16540	0.0	943.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,248VT@186801|Clostridia	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
PNCOCPKN_02000	483218.BACPEC_02596	5.21e-71	214.0	2DM28@1|root,31EE5@2|Bacteria,1VBAV@1239|Firmicutes,24NVF@186801|Clostridia,26BUP@186813|unclassified Clostridiales	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
PNCOCPKN_02001	483218.BACPEC_02597	1.07e-119	343.0	28JWV@1|root,2Z9ME@2|Bacteria,1TWU8@1239|Firmicutes,24C32@186801|Clostridia,26C6N@186813|unclassified Clostridiales	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02002	511680.BUTYVIB_01747	1.36e-241	663.0	COG0358@1|root,COG0358@2|Bacteria,1TQTJ@1239|Firmicutes,25C9F@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3991,Toprim_2
PNCOCPKN_02003	483218.BACPEC_02600	1.02e-126	360.0	COG2003@1|root,COG2003@2|Bacteria,1V38E@1239|Firmicutes,24M00@186801|Clostridia,26BWX@186813|unclassified Clostridiales	186801|Clostridia	L	RadC-like JAB domain	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
PNCOCPKN_02004	483218.BACPEC_02601	1.41e-20	81.6	28RBS@1|root,2ZDRA@2|Bacteria,1W5FZ@1239|Firmicutes,25535@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02005	585394.RHOM_16570	1.19e-233	643.0	28PM6@1|root,2Z8J4@2|Bacteria,1UXZE@1239|Firmicutes,24B7N@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02006	622312.ROSEINA2194_03920	1.07e-25	95.9	2CF7V@1|root,32X0B@2|Bacteria,1VD32@1239|Firmicutes,24NPN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02007	511680.BUTYVIB_01752	2.66e-97	283.0	2AG7F@1|root,32AN9@2|Bacteria,1V9II@1239|Firmicutes,24MKH@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02008	483218.BACPEC_02606	7.48e-220	607.0	2DBA0@1|root,2Z80J@2|Bacteria,1TQY3@1239|Firmicutes,24B0S@186801|Clostridia,268A8@186813|unclassified Clostridiales	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K18640	-	-	-	-	ko00000,ko04812	-	-	-	StbA
PNCOCPKN_02009	665950.HMPREF1025_01439	2.34e-11	63.2	COG0716@1|root,COG1143@1|root,COG0716@2|Bacteria,COG1143@2|Bacteria,1TRYM@1239|Firmicutes,247NM@186801|Clostridia,27IDD@186928|unclassified Lachnospiraceae	186801|Clostridia	C	4Fe-4S binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Flavodoxin_3,Flavodoxin_5
PNCOCPKN_02010	397290.C810_01190	3.47e-113	328.0	COG1309@1|root,COG1309@2|Bacteria,1V8TI@1239|Firmicutes,24F39@186801|Clostridia,27KFG@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
PNCOCPKN_02011	622312.ROSEINA2194_02805	0.0	1635.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia	186801|Clostridia	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
PNCOCPKN_02012	397288.C806_01857	8.87e-36	151.0	COG3209@1|root,COG3209@2|Bacteria,1UJWP@1239|Firmicutes,25FCF@186801|Clostridia,27T8Y@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Listeria-Bacteroides repeat domain (List_Bact_rpt)	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new
PNCOCPKN_02017	1235793.C809_02005	1.61e-177	529.0	28JCD@1|root,2Z972@2|Bacteria,1U75V@1239|Firmicutes,24IXT@186801|Clostridia,27TW3@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02018	1235802.C823_02927	1.13e-188	528.0	COG0463@1|root,COG0463@2|Bacteria,1UI8D@1239|Firmicutes,247P4@186801|Clostridia,25V3J@186806|Eubacteriaceae	186801|Clostridia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PNCOCPKN_02019	1235802.C823_02923	8.64e-184	532.0	COG1216@1|root,COG1216@2|Bacteria,1VVDH@1239|Firmicutes,2511J@186801|Clostridia,25ZXF@186806|Eubacteriaceae	2|Bacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PNCOCPKN_02021	1345695.CLSA_c04480	5.84e-27	116.0	COG0455@1|root,COG0455@2|Bacteria,1V3P8@1239|Firmicutes	1239|Firmicutes	D	bacterial-type flagellum organization	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
PNCOCPKN_02022	1345695.CLSA_c04480	9.9e-14	75.1	COG0455@1|root,COG0455@2|Bacteria,1V3P8@1239|Firmicutes	1239|Firmicutes	D	bacterial-type flagellum organization	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
PNCOCPKN_02024	1506994.JNLQ01000002_gene671	4.02e-79	243.0	2DGG0@1|root,2ZVUH@2|Bacteria,1W69C@1239|Firmicutes,25528@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02025	457421.CBFG_02165	7.69e-231	643.0	COG1106@1|root,COG1106@2|Bacteria,1V8YD@1239|Firmicutes	1239|Firmicutes	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
PNCOCPKN_02026	1235793.C809_01999	9.09e-64	206.0	28M5E@1|root,33F3Q@2|Bacteria,1UPUR@1239|Firmicutes,24X9U@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02027	1410625.JHWK01000005_gene1090	1.88e-122	394.0	COG0535@1|root,COG5039@1|root,COG0535@2|Bacteria,COG5039@2|Bacteria,1V2JB@1239|Firmicutes,24G9M@186801|Clostridia,27MN3@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
PNCOCPKN_02028	679200.HMPREF9333_00849	3.96e-113	331.0	COG1209@1|root,COG1209@2|Bacteria,1UZAZ@1239|Firmicutes,24A53@186801|Clostridia	186801|Clostridia	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
PNCOCPKN_02029	679200.HMPREF9333_00850	1.25e-128	372.0	COG1216@1|root,COG1216@2|Bacteria,1UGZP@1239|Firmicutes,24A6T@186801|Clostridia	186801|Clostridia	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PNCOCPKN_02030	1235835.C814_00609	7.12e-32	117.0	2DP42@1|root,330F9@2|Bacteria,1VWND@1239|Firmicutes,252K5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02031	679200.HMPREF9333_00851	6.78e-69	214.0	COG0637@1|root,COG0637@2|Bacteria,1V7NP@1239|Firmicutes,24P4T@186801|Clostridia	186801|Clostridia	S	HAD hydrolase, family IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
PNCOCPKN_02032	679200.HMPREF9333_00852	1.89e-253	719.0	COG0392@1|root,COG2334@1|root,COG0392@2|Bacteria,COG2334@2|Bacteria,1UAQ2@1239|Firmicutes,24F1I@186801|Clostridia	186801|Clostridia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
PNCOCPKN_02033	411471.SUBVAR_06969	1.14e-19	100.0	29FHK@1|root,302F9@2|Bacteria,1V5HV@1239|Firmicutes,24IB8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02034	1235792.C808_02971	3.85e-150	457.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,2480C@186801|Clostridia,27I7M@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
PNCOCPKN_02036	1235793.C809_01979	1.36e-80	262.0	COG0463@1|root,COG0463@2|Bacteria,1VVRP@1239|Firmicutes,24AI7@186801|Clostridia,27UC2@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PNCOCPKN_02037	1235793.C809_01978	1.51e-151	435.0	COG0463@1|root,COG0463@2|Bacteria,1VVRP@1239|Firmicutes,24GDS@186801|Clostridia,27UFF@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PNCOCPKN_02038	1235802.C823_02906	0.0	885.0	COG1442@1|root,COG1442@2|Bacteria,1V1F3@1239|Firmicutes,25C06@186801|Clostridia,25ZS4@186806|Eubacteriaceae	186801|Clostridia	M	Glycosyl transferase family 8	-	-	-	-	-	-	-	-	-	-	-	-	DUF4422,Glyco_transf_8
PNCOCPKN_02039	658655.HMPREF0988_01866	2.23e-216	602.0	COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,249BR@186801|Clostridia,27IA3@186928|unclassified Lachnospiraceae	186801|Clostridia	M	UDP-galactopyranose mutase	glf	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,NAD_binding_8
PNCOCPKN_02040	1235802.C823_02906	9.24e-271	760.0	COG1442@1|root,COG1442@2|Bacteria,1V1F3@1239|Firmicutes,25C06@186801|Clostridia,25ZS4@186806|Eubacteriaceae	186801|Clostridia	M	Glycosyl transferase family 8	-	-	-	-	-	-	-	-	-	-	-	-	DUF4422,Glyco_transf_8
PNCOCPKN_02041	1235802.C823_02905	1.73e-146	416.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia,25W3Y@186806|Eubacteriaceae	186801|Clostridia	GM	ABC-type polysaccharide polyol phosphate transport system, ATPase component	-	-	-	ko:K01990,ko:K09691	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC_tran
PNCOCPKN_02042	1235802.C823_02904	3.61e-144	412.0	COG1682@1|root,COG1682@2|Bacteria,1V1J2@1239|Firmicutes,25B57@186801|Clostridia,25WHV@186806|Eubacteriaceae	186801|Clostridia	U	ABC-2 type transporter	-	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
PNCOCPKN_02043	1123318.KB904586_gene406	1.16e-64	209.0	COG1215@1|root,COG1215@2|Bacteria,1V2B9@1239|Firmicutes,4HG36@91061|Bacilli	91061|Bacilli	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PNCOCPKN_02044	1195236.CTER_3937	1.81e-116	350.0	COG0438@1|root,COG0438@2|Bacteria,1TPY6@1239|Firmicutes,24834@186801|Clostridia,3WHNS@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyl transferase 4-like	epsD	-	-	ko:K19422	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
PNCOCPKN_02046	1235798.C817_00116	3.55e-98	298.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	wbpV	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
PNCOCPKN_02047	1121289.JHVL01000007_gene2812	1.98e-108	317.0	COG2148@1|root,COG2148@2|Bacteria,1TQX9@1239|Firmicutes,24874@186801|Clostridia,36VHP@31979|Clostridiaceae	186801|Clostridia	M	Bacterial sugar transferase	-	-	-	ko:K13012	-	-	-	-	ko00000,ko01005	-	-	-	Bac_transf,Epimerase
PNCOCPKN_02048	526224.Bmur_1782	2.21e-27	109.0	2DPMA@1|root,332MS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02049	1227268.HMPREF1552_01028	2.8e-72	240.0	COG3950@1|root,COG3950@2|Bacteria,3785E@32066|Fusobacteria	32066|Fusobacteria	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
PNCOCPKN_02050	622312.ROSEINA2194_02593	6.14e-308	855.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,247PW@186801|Clostridia	186801|Clostridia	GM	Polysaccharide biosynthesis protein	capD	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
PNCOCPKN_02053	658086.HMPREF0994_00358	4.88e-103	301.0	COG5340@1|root,COG5340@2|Bacteria,1TQSK@1239|Firmicutes,247JC@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
PNCOCPKN_02054	658086.HMPREF0994_00357	5.08e-154	437.0	COG2253@1|root,COG2253@2|Bacteria,1TSFX@1239|Firmicutes,24C3A@186801|Clostridia,27MX9@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
PNCOCPKN_02055	1089455.MOPEL_098_00650	1.02e-97	315.0	COG1195@1|root,COG3593@1|root,COG1195@2|Bacteria,COG3593@2|Bacteria,2I6SR@201174|Actinobacteria	201174|Actinobacteria	L	DNA synthesis involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02056	1235793.C809_00406	0.0	1427.0	COG4096@1|root,COG4096@2|Bacteria,1UI7V@1239|Firmicutes,25ED3@186801|Clostridia,27IP4@186928|unclassified Lachnospiraceae	186801|Clostridia	L	EcoEI R protein C-terminal	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF4145,EcoEI_R_C,HSDR_N,HSDR_N_2,Helicase_C,ResIII
PNCOCPKN_02057	511680.BUTYVIB_01047	4.59e-276	763.0	COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,247RY@186801|Clostridia,4BYIZ@830|Butyrivibrio	186801|Clostridia	V	HsdM N-terminal domain	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,Methylase_S,N6_Mtase
PNCOCPKN_02058	869209.Tresu_1113	2.18e-131	397.0	COG0732@1|root,COG0732@2|Bacteria,2J5QW@203691|Spirochaetes	203691|Spirochaetes	V	type I restriction	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
PNCOCPKN_02059	511680.BUTYVIB_01044	3.61e-176	493.0	COG0582@1|root,COG0582@2|Bacteria,1UJT9@1239|Firmicutes,24EEC@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
PNCOCPKN_02060	511680.BUTYVIB_02569	5.04e-82	256.0	COG0732@1|root,COG0732@2|Bacteria,1V24Y@1239|Firmicutes,24JTK@186801|Clostridia,4C1D7@830|Butyrivibrio	186801|Clostridia	V	K01154 type I restriction enzyme, S subunit	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
PNCOCPKN_02061	411467.BACCAP_04675	2.94e-24	92.8	2CCB2@1|root,32S7G@2|Bacteria,1VABI@1239|Firmicutes,24MZT@186801|Clostridia,269TP@186813|unclassified Clostridiales	186801|Clostridia	S	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
PNCOCPKN_02062	742733.HMPREF9469_05559	2.49e-172	493.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,21Z66@1506553|Lachnoclostridium	186801|Clostridia	L	COG COG4974 Site-specific recombinase XerD	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_integrase
PNCOCPKN_02063	1121115.AXVN01000132_gene727	8.7e-115	328.0	2CUHA@1|root,30KV1@2|Bacteria,1V52Z@1239|Firmicutes,24I1N@186801|Clostridia,3Y1IQ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02064	1095750.HMPREF9970_2043	6.12e-31	108.0	2C7EF@1|root,32B2X@2|Bacteria,1UH1V@1239|Firmicutes,25PQ5@186801|Clostridia,1HWGT@1164882|Lachnoanaerobaculum	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02065	936596.HMPREF1495_1511	2.71e-164	462.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,247R1@186801|Clostridia,1HW9U@1164882|Lachnoanaerobaculum	186801|Clostridia	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
PNCOCPKN_02066	575593.HMPREF0491_02876	2.7e-144	414.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia,27J9V@186928|unclassified Lachnospiraceae	186801|Clostridia	K	ParB-like nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF5348,ParBc
PNCOCPKN_02067	585394.RHOM_15640	5.2e-165	471.0	2DBC6@1|root,2Z8BZ@2|Bacteria,1TQXM@1239|Firmicutes,2484N@186801|Clostridia	186801|Clostridia	S	Replication initiator protein A	-	-	-	-	-	-	-	-	-	-	-	-	RepA_N
PNCOCPKN_02068	585394.RHOM_15635	9.25e-48	155.0	2BAQE@1|root,32NWD@2|Bacteria,1V8VM@1239|Firmicutes,24WJV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02069	397291.C804_02971	4.83e-51	171.0	2D7U9@1|root,32TPR@2|Bacteria,1VAQE@1239|Firmicutes,24I5R@186801|Clostridia,27M8P@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02070	471875.RUMLAC_01722	1.29e-232	640.0	29USC@1|root,30G4G@2|Bacteria,1UF5Z@1239|Firmicutes,24UES@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02071	469596.HMPREF9488_03814	2.59e-153	431.0	COG1476@1|root,COG1476@2|Bacteria,1V00T@1239|Firmicutes,3VSQJ@526524|Erysipelotrichia	1239|Firmicutes	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PNCOCPKN_02072	469596.HMPREF9488_03046	1.18e-251	689.0	COG2946@1|root,COG2946@2|Bacteria,1UYFS@1239|Firmicutes,3VQ0A@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Replication initiation factor	-	-	-	-	-	-	-	-	-	-	-	-	Rep_trans
PNCOCPKN_02073	1121115.AXVN01000105_gene594	3.87e-42	137.0	2CCB2@1|root,32S7G@2|Bacteria,1VABI@1239|Firmicutes,24MZT@186801|Clostridia,3Y0CD@572511|Blautia	186801|Clostridia	L	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
PNCOCPKN_02074	411460.RUMTOR_01828	3.86e-281	769.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,3XYZY@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_5,Phage_integrase
PNCOCPKN_02075	257310.BB2490	1.96e-172	513.0	COG2159@1|root,COG2159@2|Bacteria,1R8PV@1224|Proteobacteria,2VQ4H@28216|Betaproteobacteria,3T50B@506|Alcaligenaceae	28216|Betaproteobacteria	S	AIPR protein	-	-	-	-	-	-	-	-	-	-	-	-	AIPR
PNCOCPKN_02077	397291.C804_02972	6.79e-69	212.0	28I1B@1|root,30E9T@2|Bacteria,1V4JB@1239|Firmicutes,24ZUA@186801|Clostridia,27UDH@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF3801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3801
PNCOCPKN_02078	411459.RUMOBE_00652	0.0	1682.0	COG1961@1|root,COG3505@1|root,COG1961@2|Bacteria,COG3505@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3XYWF@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,T4SS-DNA_transf,Zn_ribbon_recom
PNCOCPKN_02079	411459.RUMOBE_00651	1.26e-73	221.0	2C5R4@1|root,30S72@2|Bacteria,1V578@1239|Firmicutes,24IJT@186801|Clostridia,3Y0N9@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
PNCOCPKN_02080	585394.RHOM_05265	7.49e-87	308.0	2C4YK@1|root,342PE@2|Bacteria,1VWY9@1239|Firmicutes,24TZZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02081	585394.RHOM_07305	0.0	930.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,248TP@186801|Clostridia	186801|Clostridia	E	Oligoendopeptidase f	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
PNCOCPKN_02082	1042156.CXIVA_21730	1.57e-12	64.7	COG1925@1|root,COG1925@2|Bacteria,1VAQP@1239|Firmicutes,24N19@186801|Clostridia,36M8R@31979|Clostridiaceae	186801|Clostridia	G	phosphocarrier protein HPr	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
PNCOCPKN_02083	622312.ROSEINA2194_03684	1.93e-57	182.0	2BVD7@1|root,32QT8@2|Bacteria,1V6S8@1239|Firmicutes,24HAM@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02084	471875.RUMLAC_00642	2.48e-146	421.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,3WGEP@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12020	NadA
PNCOCPKN_02085	585394.RHOM_07320	4.96e-256	706.0	COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,25E6F@186801|Clostridia	186801|Clostridia	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
PNCOCPKN_02086	585394.RHOM_07325	1.12e-167	473.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,248P2@186801|Clostridia	186801|Clostridia	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12010	QRPTase_C,QRPTase_N
PNCOCPKN_02087	585394.RHOM_07330	4.73e-96	283.0	COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,24JF2@186801|Clostridia	186801|Clostridia	K	3H domain	niaR	-	-	ko:K07105	-	-	-	-	ko00000	-	-	-	3H,HTH_11
PNCOCPKN_02088	622312.ROSEINA2194_03686	5.82e-166	469.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia	186801|Clostridia	S	TIGR00255 family	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
PNCOCPKN_02089	622312.ROSEINA2194_03687	1.19e-46	150.0	COG2052@1|root,COG2052@2|Bacteria,1VA40@1239|Firmicutes,24MXV@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0296 family	NPD7_560	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
PNCOCPKN_02090	622312.ROSEINA2194_03688	1.26e-118	342.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
PNCOCPKN_02091	622312.ROSEINA2194_03689	1.83e-44	146.0	COG1758@1|root,COG1758@2|Bacteria,1VF65@1239|Firmicutes	1239|Firmicutes	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
PNCOCPKN_02092	622312.ROSEINA2194_03690	2.37e-289	793.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
PNCOCPKN_02093	585394.RHOM_07360	1.83e-100	294.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
PNCOCPKN_02094	585394.RHOM_07365	6.8e-74	226.0	COG1546@1|root,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
PNCOCPKN_02095	585394.RHOM_07370	6.22e-96	283.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia	186801|Clostridia	L	RNA methyltransferase, RsmD family	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
PNCOCPKN_02096	585394.RHOM_07375	8.89e-101	293.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,24HC3@186801|Clostridia	186801|Clostridia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
PNCOCPKN_02097	585394.RHOM_07380	7.65e-62	198.0	COG0711@1|root,COG0711@2|Bacteria,1V97P@1239|Firmicutes,24JGQ@186801|Clostridia	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02098	585394.RHOM_07385	1.35e-102	310.0	COG3314@1|root,COG3314@2|Bacteria,1TR0V@1239|Firmicutes,247XA@186801|Clostridia	186801|Clostridia	S	Sporulation integral membrane protein YlbJ	ylbJ	-	-	-	-	-	-	-	-	-	-	-	Gate
PNCOCPKN_02099	585394.RHOM_07390	1.46e-261	727.0	COG2195@1|root,COG2195@2|Bacteria,1TQBS@1239|Firmicutes,24860@186801|Clostridia	186801|Clostridia	E	Dipeptidase	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
PNCOCPKN_02100	585394.RHOM_07395	3.53e-106	317.0	COG0739@1|root,COG0739@2|Bacteria,1TQMQ@1239|Firmicutes,24B3J@186801|Clostridia	186801|Clostridia	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
PNCOCPKN_02101	622312.ROSEINA2194_03697	1.06e-118	345.0	COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,248HC@186801|Clostridia	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rsuA	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
PNCOCPKN_02102	622312.ROSEINA2194_03698	0.0	1143.0	COG1032@1|root,COG1032@2|Bacteria,1TQ8X@1239|Firmicutes,248IW@186801|Clostridia	186801|Clostridia	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
PNCOCPKN_02103	585394.RHOM_07410	1.81e-149	430.0	COG0564@1|root,COG0564@2|Bacteria,1TR1M@1239|Firmicutes,248W3@186801|Clostridia	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
PNCOCPKN_02104	585394.RHOM_07420	4.26e-109	315.0	COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,24G7S@186801|Clostridia	186801|Clostridia	L	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation	recU	-	-	ko:K03700	-	-	-	-	ko00000,ko03400	-	-	-	RecU
PNCOCPKN_02105	622312.ROSEINA2194_03704	4.46e-203	571.0	COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,248CB@186801|Clostridia	186801|Clostridia	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
PNCOCPKN_02106	585394.RHOM_07430	4.38e-142	402.0	COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,249AR@186801|Clostridia	186801|Clostridia	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
PNCOCPKN_02107	622312.ROSEINA2194_03708	5.04e-257	711.0	COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,248X8@186801|Clostridia	186801|Clostridia	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
PNCOCPKN_02108	585394.RHOM_07440	5.47e-123	352.0	COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,247WC@186801|Clostridia	186801|Clostridia	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
PNCOCPKN_02109	585394.RHOM_07445	5.08e-269	741.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,247RS@186801|Clostridia	186801|Clostridia	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05760	His_biosynth,PRA-CH,PRA-PH
PNCOCPKN_02110	397290.C810_00822	2.94e-117	349.0	COG2865@1|root,COG2865@2|Bacteria,1US7F@1239|Firmicutes,24E9U@186801|Clostridia,27MAH@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_24
PNCOCPKN_02111	97139.C824_02725	3.39e-134	396.0	COG2865@1|root,COG2865@2|Bacteria,1US7F@1239|Firmicutes,24E9U@186801|Clostridia,36VN4@31979|Clostridiaceae	186801|Clostridia	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_24
PNCOCPKN_02112	585394.RHOM_07450	5.87e-125	370.0	COG3274@1|root,COG3274@2|Bacteria,1VSWJ@1239|Firmicutes,248AQ@186801|Clostridia	186801|Clostridia	S	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
PNCOCPKN_02114	585394.RHOM_07460	0.0	1066.0	COG1032@1|root,COG1032@2|Bacteria,1TR2C@1239|Firmicutes,248HM@186801|Clostridia	186801|Clostridia	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
PNCOCPKN_02115	585394.RHOM_07465	2.31e-123	357.0	COG5011@1|root,COG5011@2|Bacteria,1V4D0@1239|Firmicutes,249GU@186801|Clostridia	186801|Clostridia	S	Radical SAM-linked protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
PNCOCPKN_02116	585394.RHOM_07470	1.21e-159	463.0	COG1530@1|root,COG1530@2|Bacteria,1TQS4@1239|Firmicutes,247QV@186801|Clostridia	186801|Clostridia	J	ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1,TRAM
PNCOCPKN_02117	411463.EUBVEN_00827	1.07e-151	431.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,25VRX@186806|Eubacteriaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
PNCOCPKN_02118	585394.RHOM_07535	6.63e-63	192.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
PNCOCPKN_02119	622312.ROSEINA2194_03721	1.19e-62	192.0	COG2868@1|root,COG2868@2|Bacteria	2|Bacteria	J	Cysteine protease Prp	ysxB	-	-	ko:K07584	-	-	-	-	ko00000	-	-	-	Peptidase_Prp
PNCOCPKN_02120	622312.ROSEINA2194_03722	1.9e-61	188.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
PNCOCPKN_02121	585394.RHOM_07550	2.47e-290	795.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
PNCOCPKN_02122	585394.RHOM_07555	4.22e-51	162.0	COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,24QZB@186801|Clostridia	186801|Clostridia	J	RNA-binding protein, YhbY family	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
PNCOCPKN_02123	585394.RHOM_07560	4.18e-86	260.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
PNCOCPKN_02124	585394.RHOM_07565	8.96e-103	301.0	COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,24HN2@186801|Clostridia	186801|Clostridia	H	Hydrolase, HD family	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,HD
PNCOCPKN_02125	585394.RHOM_07570	1.3e-62	193.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,24MVA@186801|Clostridia	186801|Clostridia	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
PNCOCPKN_02126	585394.RHOM_07575	1.09e-127	365.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia	186801|Clostridia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
PNCOCPKN_02127	658086.HMPREF0994_02833	3.13e-20	85.9	COG1388@1|root,COG1388@2|Bacteria,1VK5T@1239|Firmicutes,24UT1@186801|Clostridia,27Q7D@186928|unclassified Lachnospiraceae	186801|Clostridia	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
PNCOCPKN_02128	585394.RHOM_07585	5.38e-149	422.0	COG0204@1|root,COG0204@2|Bacteria,1TTPK@1239|Firmicutes,24B6K@186801|Clostridia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
PNCOCPKN_02129	585394.RHOM_07590	1.65e-212	591.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,25C3N@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	xerS	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
PNCOCPKN_02130	1235799.C818_03095	8.76e-121	350.0	COG0037@1|root,COG0037@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia,27IBK@186928|unclassified Lachnospiraceae	186801|Clostridia	D	PP-loop family	ttcA2	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3,Rhodanese
PNCOCPKN_02132	622312.ROSEINA2194_03741	3.03e-82	245.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
PNCOCPKN_02135	180332.JTGN01000006_gene3187	7.08e-08	62.4	COG3468@1|root,COG3934@1|root,COG4409@1|root,COG4733@1|root,COG5492@1|root,COG3468@2|Bacteria,COG3934@2|Bacteria,COG4409@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria,1UI9U@1239|Firmicutes,24C9Z@186801|Clostridia	186801|Clostridia	G	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Big_3,DUF4091,Laminin_G_3,Lipase_GDSL_2
PNCOCPKN_02136	585394.RHOM_07605	8.89e-129	368.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
PNCOCPKN_02137	622312.ROSEINA2194_03746	3.07e-189	529.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
PNCOCPKN_02138	585394.RHOM_07615	1.06e-61	196.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
PNCOCPKN_02139	585394.RHOM_07620	6.77e-180	510.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
PNCOCPKN_02140	622312.ROSEINA2194_03750	1.03e-124	361.0	COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,24GDV@186801|Clostridia	186801|Clostridia	S	S4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S4
PNCOCPKN_02141	585394.RHOM_07630	3.65e-79	240.0	COG1799@1|root,COG1799@2|Bacteria,1V5NF@1239|Firmicutes,25CNH@186801|Clostridia	186801|Clostridia	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
PNCOCPKN_02142	585394.RHOM_07635	2.36e-138	394.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
PNCOCPKN_02143	622312.ROSEINA2194_03753	3.7e-213	602.0	COG0845@1|root,COG0845@2|Bacteria,1TRN9@1239|Firmicutes,248G2@186801|Clostridia	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02144	585394.RHOM_07645	3.66e-37	125.0	COG2155@1|root,COG2155@2|Bacteria,1VEQJ@1239|Firmicutes,24QKW@186801|Clostridia	186801|Clostridia	S	Conserved protein	-	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
PNCOCPKN_02145	585394.RHOM_07650	6.25e-75	226.0	COG0593@1|root,COG0593@2|Bacteria,1VAFE@1239|Firmicutes,25E3U@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02146	585394.RHOM_07655	1.97e-163	465.0	COG1686@1|root,COG1686@2|Bacteria,1TU06@1239|Firmicutes,25B23@186801|Clostridia	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
PNCOCPKN_02147	585394.RHOM_07660	8.95e-91	265.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia	186801|Clostridia	G	methylglyoxal synthase	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
PNCOCPKN_02148	585394.RHOM_07665	6.81e-197	553.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,247WS@186801|Clostridia	186801|Clostridia	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
PNCOCPKN_02149	622312.ROSEINA2194_03759	1.23e-16	73.6	COG0851@1|root,COG0851@2|Bacteria	2|Bacteria	D	regulation of division septum assembly	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
PNCOCPKN_02150	585394.RHOM_07675	4.57e-120	351.0	COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,249BB@186801|Clostridia	186801|Clostridia	D	Belongs to the ParA family	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA,ParA
PNCOCPKN_02151	585394.RHOM_07685	0.0	1333.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,2480Z@186801|Clostridia	186801|Clostridia	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
PNCOCPKN_02152	585394.RHOM_07690	1.4e-91	271.0	COG2891@1|root,COG2891@2|Bacteria,1V1EJ@1239|Firmicutes,24GF4@186801|Clostridia	186801|Clostridia	M	rod shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
PNCOCPKN_02153	585394.RHOM_07695	1.83e-147	421.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
PNCOCPKN_02154	585394.RHOM_07700	4.99e-213	592.0	COG1077@1|root,COG1077@2|Bacteria,1TPVU@1239|Firmicutes,248CM@186801|Clostridia	186801|Clostridia	D	Cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
PNCOCPKN_02155	585394.RHOM_07705	2.19e-91	275.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia	186801|Clostridia	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
PNCOCPKN_02157	585394.RHOM_07710	5.91e-282	774.0	COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,247Y4@186801|Clostridia	186801|Clostridia	P	aluminum resistance protein	ynbB	-	-	-	-	-	-	-	-	-	-	-	Met_gamma_lyase
PNCOCPKN_02158	622312.ROSEINA2194_03770	7.93e-179	503.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia	186801|Clostridia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
PNCOCPKN_02159	622312.ROSEINA2194_03771	0.0	909.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
PNCOCPKN_02160	1235802.C823_03200	1.45e-100	298.0	COG1351@1|root,COG1351@2|Bacteria,1TRAA@1239|Firmicutes,249DJ@186801|Clostridia,25V4I@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
PNCOCPKN_02161	585394.RHOM_07725	0.0	1494.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
PNCOCPKN_02162	585394.RHOM_07730	6.99e-253	709.0	COG2509@1|root,COG2509@2|Bacteria,1TPBW@1239|Firmicutes,247TR@186801|Clostridia	186801|Clostridia	H	'oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	HI0933_like,NAD_binding_8,Pyr_redox_2
PNCOCPKN_02163	622312.ROSEINA2194_03775	6.64e-175	502.0	COG2081@1|root,COG2081@2|Bacteria,1TR7U@1239|Firmicutes,2497W@186801|Clostridia	186801|Clostridia	S	Flavoprotein family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
PNCOCPKN_02164	397288.C806_02312	2.5e-10	61.6	2EJV3@1|root,33DJR@2|Bacteria,1VKNR@1239|Firmicutes,24UH1@186801|Clostridia,27TPQ@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02165	585394.RHOM_07745	9.6e-261	730.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia	186801|Clostridia	S	Stage V sporulation protein B	spoVB1	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
PNCOCPKN_02166	622312.ROSEINA2194_03780	1.08e-87	260.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia	186801|Clostridia	F	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
PNCOCPKN_02167	585394.RHOM_07755	2.53e-109	333.0	COG1480@1|root,COG1480@2|Bacteria	2|Bacteria	O	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	-
PNCOCPKN_02168	585394.RHOM_07760	3.5e-207	577.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia	186801|Clostridia	T	phosphate starvation-inducible protein	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
PNCOCPKN_02169	585394.RHOM_07765	3.51e-162	469.0	COG0561@1|root,COG0561@2|Bacteria,1TR3N@1239|Firmicutes,24ACD@186801|Clostridia	186801|Clostridia	S	Sporulation protein YqfD	yqfD	-	-	ko:K06438	-	-	-	-	ko00000	-	-	-	YqfD
PNCOCPKN_02170	1235790.C805_01829	1.94e-29	107.0	2B2ZJ@1|root,31VKQ@2|Bacteria,1TVEP@1239|Firmicutes,25NEX@186801|Clostridia,25XCH@186806|Eubacteriaceae	186801|Clostridia	S	YabP family	-	-	-	-	-	-	-	-	-	-	-	-	YabP
PNCOCPKN_02171	585394.RHOM_07775	7.43e-234	652.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,24848@186801|Clostridia	186801|Clostridia	F	pyrimidine-nucleoside phosphorylase	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08925	Glycos_trans_3N,Glycos_transf_3,PYNP_C
PNCOCPKN_02172	411490.ANACAC_03749	1.04e-21	94.4	COG2068@1|root,COG2068@2|Bacteria,1VA0F@1239|Firmicutes,24NSX@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
PNCOCPKN_02173	622312.ROSEINA2194_03787	0.0	1269.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia	186801|Clostridia	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	xdhD	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
PNCOCPKN_02174	622312.ROSEINA2194_03788	7.67e-87	257.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24HQN@186801|Clostridia	186801|Clostridia	C	aerobic-type carbon monoxide dehydrogenase, small subunit CoxS	hcrC	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
PNCOCPKN_02175	622312.ROSEINA2194_03789	2.87e-116	341.0	COG1319@1|root,COG1319@2|Bacteria,1TSNH@1239|Firmicutes,24A57@186801|Clostridia	186801|Clostridia	C	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
PNCOCPKN_02176	33035.JPJF01000004_gene1973	5.17e-53	180.0	COG2340@1|root,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,24BAQ@186801|Clostridia	186801|Clostridia	V	PFAM SCP-like extracellular	safA	-	-	-	-	-	-	-	-	-	-	-	CAP,LysM
PNCOCPKN_02177	553973.CLOHYLEM_07594	1.22e-134	383.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,24899@186801|Clostridia,21Y4Q@1506553|Lachnoclostridium	186801|Clostridia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
PNCOCPKN_02178	742765.HMPREF9457_00537	8.2e-194	548.0	COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,247R4@186801|Clostridia,27WJP@189330|Dorea	186801|Clostridia	P	Voltage gated chloride channel	eriC	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
PNCOCPKN_02179	1256908.HMPREF0373_02751	1.81e-287	794.0	COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,248NQ@186801|Clostridia,25V4N@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21.2	-	-	SSF
PNCOCPKN_02180	1280390.CBQR020000002_gene18	7.06e-192	551.0	COG3507@1|root,COG3507@2|Bacteria,1UY12@1239|Firmicutes,4HEUT@91061|Bacilli,27497@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.37,3.2.1.55	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	-	R01433,R01762	RC00467	ko00000,ko00001,ko01000	-	GH43,GH51	-	Glyco_hydro_43
PNCOCPKN_02181	585394.RHOM_07785	1.16e-81	245.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia	186801|Clostridia	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
PNCOCPKN_02183	622312.ROSEINA2194_03792	7.47e-104	303.0	COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,249VC@186801|Clostridia	186801|Clostridia	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis	xpt	-	2.4.2.22	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
PNCOCPKN_02184	622312.ROSEINA2194_03801	2.21e-94	294.0	COG0457@1|root,COG0457@2|Bacteria,1UZDE@1239|Firmicutes,2491Z@186801|Clostridia	186801|Clostridia	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Fn3_assoc,TPR_16,TPR_19,TPR_8,zinc_ribbon_2
PNCOCPKN_02185	585394.RHOM_07810	0.0	1000.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia	186801|Clostridia	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
PNCOCPKN_02186	585394.RHOM_07815	0.0	1090.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia	186801|Clostridia	D	FtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
PNCOCPKN_02187	585394.RHOM_07820	8e-150	428.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
PNCOCPKN_02188	585394.RHOM_07825	3.67e-125	360.0	COG0740@1|root,COG0740@2|Bacteria,1TPX2@1239|Firmicutes,249QX@186801|Clostridia	186801|Clostridia	OU	Protease subunit of ATP-dependent	tepA	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
PNCOCPKN_02189	585394.RHOM_07830	0.0	920.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
PNCOCPKN_02190	585394.RHOM_07835	4.31e-150	424.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia	186801|Clostridia	K	transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
PNCOCPKN_02191	585394.RHOM_07845	2.16e-70	213.0	COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,24JE1@186801|Clostridia	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	ndoA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
PNCOCPKN_02192	622312.ROSEINA2194_03813	1.54e-212	595.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
PNCOCPKN_02193	585394.RHOM_07850	5.01e-176	512.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
PNCOCPKN_02194	585394.RHOM_07855	2.74e-139	395.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia	186801|Clostridia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
PNCOCPKN_02195	585394.RHOM_07860	0.0	971.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia	186801|Clostridia	S	Abc transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
PNCOCPKN_02196	585394.RHOM_07865	5.04e-278	761.0	COG0538@1|root,COG0538@2|Bacteria,1TSKB@1239|Firmicutes,247KX@186801|Clostridia	186801|Clostridia	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
PNCOCPKN_02197	585394.RHOM_07870	3.78e-126	362.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24E6I@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
PNCOCPKN_02198	585394.RHOM_07875	0.0	923.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2495J@186801|Clostridia	186801|Clostridia	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0036440,GO:0046912,GO:0050450	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS03250	HMGL-like
PNCOCPKN_02201	585394.RHOM_07895	3.31e-51	164.0	2EJ0U@1|root,33CS0@2|Bacteria,1VKD6@1239|Firmicutes,24W6Q@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02202	622312.ROSEINA2194_03829	2.17e-35	122.0	2BC9Q@1|root,325UU@2|Bacteria,1URUY@1239|Firmicutes,24WWT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02203	585394.RHOM_07905	5.82e-213	600.0	COG3391@1|root,COG5492@1|root,COG3391@2|Bacteria,COG5492@2|Bacteria,1TR9I@1239|Firmicutes,24CXQ@186801|Clostridia	186801|Clostridia	M	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new
PNCOCPKN_02204	585394.RHOM_07910	0.0	1262.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia	186801|Clostridia	J	elongation factor g	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
PNCOCPKN_02205	585394.RHOM_07915	2.2e-188	531.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia	186801|Clostridia	E	prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
PNCOCPKN_02207	1408312.JNJS01000006_gene701	7.53e-34	130.0	COG5434@1|root,COG5434@2|Bacteria,1TSA5@1239|Firmicutes,24B0W@186801|Clostridia,3NHBQ@46205|Pseudobutyrivibrio	186801|Clostridia	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02208	140626.JHWB01000016_gene2464	3.24e-46	151.0	2E11F@1|root,32WHB@2|Bacteria,1VD34@1239|Firmicutes,24NEB@186801|Clostridia	186801|Clostridia	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
PNCOCPKN_02209	585394.RHOM_07945	6.84e-230	635.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia	186801|Clostridia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
PNCOCPKN_02210	1256908.HMPREF0373_02472	0.0	1302.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,25UVH@186806|Eubacteriaceae	186801|Clostridia	J	phenylalanyl-tRNA synthetase (beta subunit)	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
PNCOCPKN_02211	483218.BACPEC_01341	2.54e-209	582.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,267UI@186813|unclassified Clostridiales	186801|Clostridia	J	Aminoacyl tRNA synthetase class II, N-terminal domain	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
PNCOCPKN_02212	585394.RHOM_07960	2.63e-149	426.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,24A2Q@186801|Clostridia	186801|Clostridia	H	Belongs to the UPF0761 family	yihY	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
PNCOCPKN_02213	585394.RHOM_07965	1.98e-262	750.0	COG2385@1|root,COG2385@2|Bacteria,1UW6J@1239|Firmicutes,24CYM@186801|Clostridia	186801|Clostridia	D	SpoIID LytB domain protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
PNCOCPKN_02214	1256908.HMPREF0373_02866	9.64e-133	391.0	COG0194@1|root,COG4502@1|root,COG0194@2|Bacteria,COG4502@2|Bacteria,1V87A@1239|Firmicutes,24SD2@186801|Clostridia	186801|Clostridia	F	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_kin,NT5C
PNCOCPKN_02215	411474.COPEUT_01787	0.0	991.0	COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia	186801|Clostridia	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
PNCOCPKN_02216	585394.RHOM_14095	1.06e-72	234.0	COG0840@1|root,COG0840@2|Bacteria,1TY0J@1239|Firmicutes,24DGH@186801|Clostridia	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
PNCOCPKN_02217	585394.RHOM_14090	1.42e-179	508.0	COG3287@1|root,COG3287@2|Bacteria,1UK57@1239|Firmicutes,24D5K@186801|Clostridia	186801|Clostridia	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
PNCOCPKN_02218	585394.RHOM_07975	2.53e-69	212.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,24JEM@186801|Clostridia	186801|Clostridia	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
PNCOCPKN_02219	622312.ROSEINA2194_03850	9.43e-286	785.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia	186801|Clostridia	C	citrate synthase	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
PNCOCPKN_02220	585394.RHOM_07985	5.21e-231	653.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
PNCOCPKN_02221	585394.RHOM_07990	1.11e-139	397.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07775	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
PNCOCPKN_02222	622312.ROSEINA2194_03851	3.6e-43	144.0	2EH8T@1|root,33B0N@2|Bacteria,1VKIJ@1239|Firmicutes,24V3Q@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02223	585394.RHOM_08000	2.11e-59	186.0	COG4753@1|root,COG4753@2|Bacteria,1VAG0@1239|Firmicutes,24P6B@186801|Clostridia	186801|Clostridia	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_18,Response_reg
PNCOCPKN_02224	585394.RHOM_08005	8.35e-107	319.0	COG1406@1|root,COG1406@2|Bacteria,1V46M@1239|Firmicutes,24B3C@186801|Clostridia	186801|Clostridia	N	Chemotaxis phosphatase CheX	-	-	-	-	-	-	-	-	-	-	-	-	CheX
PNCOCPKN_02225	622312.ROSEINA2194_03854	2.51e-310	852.0	COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia	186801|Clostridia	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS16355	PALP,Thr_synth_N
PNCOCPKN_02226	585394.RHOM_08020	3.18e-127	369.0	28NT4@1|root,2ZBRW@2|Bacteria,1UXVI@1239|Firmicutes,24ABY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02227	483218.BACPEC_02992	1.99e-101	320.0	COG0840@1|root,COG0840@2|Bacteria,1TSW1@1239|Firmicutes,24B19@186801|Clostridia	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
PNCOCPKN_02228	1235802.C823_03008	5.47e-266	751.0	COG0840@1|root,COG1145@1|root,COG4624@1|root,COG0840@2|Bacteria,COG1145@2|Bacteria,COG4624@2|Bacteria,1TSVR@1239|Firmicutes,248TC@186801|Clostridia,25VKU@186806|Eubacteriaceae	186801|Clostridia	CNT	Iron only hydrogenase large subunit, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fe_hyd_lg_C,Fer4,Fer4_10,Fer4_7,MCPsignal
PNCOCPKN_02229	585394.RHOM_08335	1.03e-156	443.0	COG1036@1|root,COG2878@1|root,COG1036@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia	186801|Clostridia	C	electron transport complex, RnfABCDGE type, B subunit	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_13,Fer4_4,Fer4_9
PNCOCPKN_02230	585394.RHOM_08340	4.83e-123	352.0	COG4657@1|root,COG4657@2|Bacteria,1TS06@1239|Firmicutes,247UE@186801|Clostridia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
PNCOCPKN_02231	585394.RHOM_08345	9.91e-139	395.0	COG4660@1|root,COG4660@2|Bacteria,1TSE7@1239|Firmicutes,24972@186801|Clostridia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	iHN637.CLJU_RS05585	Rnf-Nqr
PNCOCPKN_02232	585394.RHOM_08350	3.91e-106	310.0	COG4659@1|root,COG4659@2|Bacteria,1V7R1@1239|Firmicutes,24JVM@186801|Clostridia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfG	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
PNCOCPKN_02233	585394.RHOM_08355	1.52e-185	520.0	COG4658@1|root,COG4658@2|Bacteria,1TQAY@1239|Firmicutes,247TM@186801|Clostridia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
PNCOCPKN_02234	585394.RHOM_08360	3.65e-278	765.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia	186801|Clostridia	C	Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4,Fer4_10,Fer4_7,Fer4_9,RnfC_N,SLBB
PNCOCPKN_02235	585394.RHOM_08365	2.22e-125	374.0	COG3359@1|root,COG3359@2|Bacteria,1U725@1239|Firmicutes,24A9V@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
PNCOCPKN_02236	397290.C810_00991	2.15e-34	151.0	COG4886@1|root,COG5492@1|root,COG4886@2|Bacteria,COG5492@2|Bacteria,1V32P@1239|Firmicutes,25FDC@186801|Clostridia,27UE2@186928|unclassified Lachnospiraceae	186801|Clostridia	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
PNCOCPKN_02237	585394.RHOM_08370	5.93e-166	466.0	COG1352@1|root,COG1352@2|Bacteria,1TPD8@1239|Firmicutes,24AQJ@186801|Clostridia	186801|Clostridia	NT	PFAM MCP methyltransferase, CheR-type	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
PNCOCPKN_02238	585394.RHOM_08375	1.19e-240	664.0	COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia	186801|Clostridia	J	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
PNCOCPKN_02239	585394.RHOM_08380	4.43e-151	431.0	COG0761@1|root,COG0761@2|Bacteria,1UHT7@1239|Firmicutes,25E67@186801|Clostridia	186801|Clostridia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB
PNCOCPKN_02240	585394.RHOM_08385	4.29e-128	367.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
PNCOCPKN_02241	622312.ROSEINA2194_00502	3.64e-223	624.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,247S5@186801|Clostridia	186801|Clostridia	S	Flavoprotein family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
PNCOCPKN_02242	585394.RHOM_08395	8.75e-193	538.0	COG1737@1|root,COG1737@2|Bacteria,1TP7H@1239|Firmicutes,248ZD@186801|Clostridia	186801|Clostridia	K	transcriptional regulator RpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
PNCOCPKN_02243	1235793.C809_02550	0.0	945.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,27IE8@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PNCOCPKN_02244	585394.RHOM_08405	0.0	892.0	COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia	186801|Clostridia	C	carboxylase	oadA	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
PNCOCPKN_02245	585394.RHOM_08410	1.32e-253	698.0	COG1883@1|root,COG1883@2|Bacteria,1TPEP@1239|Firmicutes,248ET@186801|Clostridia	186801|Clostridia	C	decarboxylase beta subunit	gcdB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
PNCOCPKN_02246	622312.ROSEINA2194_00498	4.57e-53	169.0	COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia	186801|Clostridia	I	PFAM biotin lipoyl attachment domain-containing protein	gcdC	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
PNCOCPKN_02247	585394.RHOM_08420	2.13e-95	286.0	2DMIV@1|root,32RW6@2|Bacteria,1VAMW@1239|Firmicutes,24DVC@186801|Clostridia	186801|Clostridia	P	decarboxylase gamma	-	-	-	-	-	-	-	-	-	-	-	-	DUF3887,OAD_gamma
PNCOCPKN_02248	585394.RHOM_08425	3.69e-290	798.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia	186801|Clostridia	I	acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
PNCOCPKN_02249	585394.RHOM_08430	1.72e-176	504.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia	186801|Clostridia	M	Belongs to the peptidase S11 family	dacB2	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
PNCOCPKN_02250	585394.RHOM_08435	2.58e-109	317.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,24JW7@186801|Clostridia	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
PNCOCPKN_02251	585394.RHOM_08440	7.14e-141	402.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,249VW@186801|Clostridia	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
PNCOCPKN_02252	585394.RHOM_08445	1.53e-180	514.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,249B3@186801|Clostridia	186801|Clostridia	M	Belongs to the peptidase S11 family	dacF	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
PNCOCPKN_02253	585394.RHOM_08450	1.02e-276	767.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
PNCOCPKN_02254	585394.RHOM_08455	1.42e-150	432.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,249H1@186801|Clostridia	186801|Clostridia	O	Belongs to the peptidase S8 family	aprX	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
PNCOCPKN_02255	585394.RHOM_07130	9.28e-294	810.0	COG0589@1|root,COG0589@2|Bacteria,1TPUI@1239|Firmicutes,24826@186801|Clostridia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
PNCOCPKN_02256	585394.RHOM_07125	1.79e-110	323.0	COG0347@1|root,COG0347@2|Bacteria,1V65X@1239|Firmicutes,24HQ8@186801|Clostridia	186801|Clostridia	E	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02257	585394.RHOM_08460	0.0	1291.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
PNCOCPKN_02258	585394.RHOM_08465	3.3e-48	154.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
PNCOCPKN_02259	585394.RHOM_08470	5.9e-165	476.0	COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG3103@2|Bacteria,COG4991@2|Bacteria,1UBS0@1239|Firmicutes,25B2D@186801|Clostridia	186801|Clostridia	M	NlpC p60 family protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
PNCOCPKN_02260	585394.RHOM_08475	2.01e-172	486.0	COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,2484A@186801|Clostridia	186801|Clostridia	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
PNCOCPKN_02261	622312.ROSEINA2194_00453	3.3e-156	446.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,24B46@186801|Clostridia	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
PNCOCPKN_02262	585394.RHOM_08485	2.73e-167	474.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia	186801|Clostridia	J	domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
PNCOCPKN_02263	622312.ROSEINA2194_00455	5.93e-66	202.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
PNCOCPKN_02264	585394.RHOM_08495	0.0	1234.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
PNCOCPKN_02265	585394.RHOM_08500	1.52e-51	164.0	COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,24QP3@186801|Clostridia	186801|Clostridia	J	ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
PNCOCPKN_02266	585394.RHOM_08505	1.43e-48	156.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,24QSJ@186801|Clostridia	186801|Clostridia	K	Nucleic-acid-binding protein implicated in transcription termination	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
PNCOCPKN_02267	585394.RHOM_08510	1.44e-232	647.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
PNCOCPKN_02268	585394.RHOM_08515	3.83e-99	288.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,24N1G@186801|Clostridia	186801|Clostridia	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
PNCOCPKN_02272	742765.HMPREF9457_03255	7.21e-145	421.0	COG2070@1|root,COG2070@2|Bacteria,1TPX1@1239|Firmicutes,247YZ@186801|Clostridia,27V3C@189330|Dorea	186801|Clostridia	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
PNCOCPKN_02273	622312.ROSEINA2194_03681	2.31e-234	645.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
PNCOCPKN_02274	585394.RHOM_08530	3.55e-173	486.0	COG2207@1|root,COG2207@2|Bacteria,1UZ0Q@1239|Firmicutes,24YIV@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
PNCOCPKN_02275	585394.RHOM_08535	2.23e-126	364.0	COG0613@1|root,COG0613@2|Bacteria,1V33M@1239|Firmicutes,24H1U@186801|Clostridia	186801|Clostridia	S	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP,PHP_C
PNCOCPKN_02276	622312.ROSEINA2194_01009	1.33e-70	213.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia	186801|Clostridia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
PNCOCPKN_02277	585394.RHOM_08100	2.92e-34	117.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
PNCOCPKN_02278	585394.RHOM_08105	1.78e-102	298.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,24FUS@186801|Clostridia	186801|Clostridia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
PNCOCPKN_02279	397288.C806_03378	9.13e-159	472.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,27KAK@186928|unclassified Lachnospiraceae	186801|Clostridia	NT	Four helix bundle sensory module for signal transduction	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal,dCache_1
PNCOCPKN_02280	622312.ROSEINA2194_02490	2.27e-58	185.0	COG0835@1|root,COG0835@2|Bacteria	2|Bacteria	NT	chemotaxis	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
PNCOCPKN_02281	585394.RHOM_08120	1.63e-143	412.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,248H2@186801|Clostridia	186801|Clostridia	S	PHP domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
PNCOCPKN_02282	585394.RHOM_08125	3.83e-130	376.0	COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,24PNN@186801|Clostridia	186801|Clostridia	S	HAD-superfamily hydrolase, subfamily IIB	yidA	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
PNCOCPKN_02283	585394.RHOM_08130	0.0	1185.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia	186801|Clostridia	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
PNCOCPKN_02284	622312.ROSEINA2194_01001	1.42e-278	772.0	COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,248EW@186801|Clostridia	186801|Clostridia	FP	Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
PNCOCPKN_02285	585394.RHOM_08140	7.35e-264	728.0	COG2607@1|root,COG2607@2|Bacteria,1TQDJ@1239|Firmicutes,2483S@186801|Clostridia	186801|Clostridia	E	ATPase (AAA superfamily)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
PNCOCPKN_02286	585394.RHOM_08145	1.67e-217	606.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1TPDN@1239|Firmicutes,248G7@186801|Clostridia	186801|Clostridia	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
PNCOCPKN_02287	622312.ROSEINA2194_00998	1.62e-102	311.0	COG0823@1|root,COG0823@2|Bacteria,1V60E@1239|Firmicutes,24I0N@186801|Clostridia	186801|Clostridia	U	Domain of unknown function (DUF5050)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5050
PNCOCPKN_02288	622312.ROSEINA2194_00997	0.0	2598.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,248YB@186801|Clostridia	186801|Clostridia	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
PNCOCPKN_02289	585394.RHOM_07195	1.58e-224	622.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
PNCOCPKN_02290	622312.ROSEINA2194_00995	1.41e-190	535.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia	186801|Clostridia	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
PNCOCPKN_02291	585394.RHOM_07185	3.87e-207	580.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
PNCOCPKN_02292	622312.ROSEINA2194_00993	1.79e-148	422.0	COG0575@1|root,COG0575@2|Bacteria,1UPNB@1239|Firmicutes,248BP@186801|Clostridia	186801|Clostridia	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
PNCOCPKN_02293	585394.RHOM_07175	4.9e-145	412.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
PNCOCPKN_02294	622312.ROSEINA2194_00991	3.3e-107	311.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia	186801|Clostridia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
PNCOCPKN_02295	585394.RHOM_07165	2.35e-151	427.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,247KR@186801|Clostridia	186801|Clostridia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
PNCOCPKN_02296	622312.ROSEINA2194_00989	1.24e-78	246.0	COG1664@1|root,COG1664@2|Bacteria,1TS93@1239|Firmicutes,24DZX@186801|Clostridia	186801|Clostridia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
PNCOCPKN_02297	622312.ROSEINA2194_00988	3.44e-148	427.0	COG0726@1|root,COG0726@2|Bacteria,1V1X7@1239|Firmicutes,25B6U@186801|Clostridia	186801|Clostridia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
PNCOCPKN_02298	1410626.JHXB01000007_gene2561	6.36e-84	260.0	COG2035@1|root,COG2035@2|Bacteria,1UYD5@1239|Firmicutes,24B08@186801|Clostridia,27KSJ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF368)	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
PNCOCPKN_02299	1232452.BAIB02000016_gene2390	2.41e-221	630.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,2681R@186813|unclassified Clostridiales	186801|Clostridia	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
PNCOCPKN_02300	585394.RHOM_01235	0.0	908.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia	186801|Clostridia	G	Alpha amylase catalytic	-	-	3.2.1.1,3.2.1.10	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459
PNCOCPKN_02301	622312.ROSEINA2194_02238	4.29e-120	353.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UXKB@1239|Firmicutes,24DXK@186801|Clostridia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
PNCOCPKN_02302	411461.DORFOR_00003	2.25e-16	70.9	2BRZP@1|root,32M03@2|Bacteria,1USSV@1239|Firmicutes,25AUB@186801|Clostridia,27X99@189330|Dorea	186801|Clostridia	S	Psort location Extracellular, score 8.82	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02303	1232453.BAIF02000089_gene2922	6.67e-301	820.0	COG4974@1|root,COG4974@2|Bacteria,1UMMQ@1239|Firmicutes,25GMC@186801|Clostridia	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
PNCOCPKN_02304	500632.CLONEX_03137	8.26e-252	691.0	COG2946@1|root,COG2946@2|Bacteria,1TST2@1239|Firmicutes,24A2M@186801|Clostridia	2|Bacteria	L	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07467	-	-	-	-	ko00000	-	-	-	HTH_3,Rep_trans
PNCOCPKN_02305	411461.DORFOR_03132	1.02e-72	218.0	2CE0F@1|root,30MHA@2|Bacteria,1V40C@1239|Firmicutes,24I3C@186801|Clostridia,27WRJ@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02306	500632.CLONEX_03139	1.28e-156	440.0	COG1396@1|root,COG1396@2|Bacteria,1VM51@1239|Firmicutes,24FE9@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PNCOCPKN_02307	445972.ANACOL_03123	1.13e-48	154.0	2CB7P@1|root,32X35@2|Bacteria,1VCII@1239|Firmicutes,24Q2Q@186801|Clostridia,3WPN5@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4318)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4318
PNCOCPKN_02308	585394.RHOM_07120	2.43e-195	545.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
PNCOCPKN_02309	585394.RHOM_07115	1.17e-163	459.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia	186801|Clostridia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
PNCOCPKN_02310	622312.ROSEINA2194_00984	1.59e-46	158.0	COG1559@1|root,COG1559@2|Bacteria,1VF4Y@1239|Firmicutes,24RCQ@186801|Clostridia	186801|Clostridia	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	-	-	-	-	-	-	-	-	-	-	-	-	YceG
PNCOCPKN_02311	585394.RHOM_07105	7.12e-57	187.0	COG3064@1|root,COG3064@2|Bacteria,1V968@1239|Firmicutes,24KD3@186801|Clostridia	186801|Clostridia	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02312	585394.RHOM_07100	1.1e-32	117.0	2ECFD@1|root,336DM@2|Bacteria,1VHDX@1239|Firmicutes,24TE9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02313	622312.ROSEINA2194_00979	1.6e-133	384.0	COG1191@1|root,COG1191@2|Bacteria,1TP9K@1239|Firmicutes,248M0@186801|Clostridia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
PNCOCPKN_02314	585394.RHOM_07090	3.96e-22	89.4	2E8TH@1|root,33348@2|Bacteria,1VJ8V@1239|Firmicutes,24SQI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02315	585394.RHOM_07085	4.4e-101	294.0	COG1871@1|root,COG1871@2|Bacteria,1V70X@1239|Firmicutes,24HH7@186801|Clostridia	186801|Clostridia	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
PNCOCPKN_02316	585394.RHOM_07080	1.03e-121	350.0	COG1776@1|root,COG1776@2|Bacteria,1UNKB@1239|Firmicutes,247MX@186801|Clostridia	186801|Clostridia	NT	Chemotaxis protein CheC, inhibitor of MCP methylation	cheC	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
PNCOCPKN_02317	585394.RHOM_07075	3.02e-79	238.0	COG0835@1|root,COG0835@2|Bacteria,1V4HH@1239|Firmicutes,24JV4@186801|Clostridia	186801|Clostridia	NT	PFAM CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
PNCOCPKN_02318	585394.RHOM_07070	0.0	1067.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1TPMS@1239|Firmicutes,24858@186801|Clostridia	186801|Clostridia	T	Signal transducing histidine kinase homodimeric	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
PNCOCPKN_02319	622312.ROSEINA2194_00972	6.51e-190	535.0	COG2201@1|root,COG2201@2|Bacteria,1TRHC@1239|Firmicutes,249FD@186801|Clostridia	186801|Clostridia	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
PNCOCPKN_02320	622312.ROSEINA2194_00971	1.57e-86	264.0	COG5581@1|root,COG5581@2|Bacteria,1VCR9@1239|Firmicutes	1239|Firmicutes	M	Flagellar protein YcgR	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR_2
PNCOCPKN_02321	1235790.C805_01994	6.5e-121	355.0	COG0455@1|root,COG0455@2|Bacteria,1TRZ5@1239|Firmicutes,24AIN@186801|Clostridia,25VBY@186806|Eubacteriaceae	186801|Clostridia	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	flhG	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	CbiA,ParA
PNCOCPKN_02322	585394.RHOM_07050	4.21e-195	553.0	COG1419@1|root,COG1419@2|Bacteria,1TSP7@1239|Firmicutes,249R1@186801|Clostridia	186801|Clostridia	N	PFAM GTP-binding signal recognition particle SRP54 G- domain	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
PNCOCPKN_02323	622312.ROSEINA2194_00968	0.0	1124.0	COG1298@1|root,COG1298@2|Bacteria,1TQBM@1239|Firmicutes,248F5@186801|Clostridia	186801|Clostridia	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
PNCOCPKN_02324	585394.RHOM_07040	8.25e-206	577.0	COG1377@1|root,COG1377@2|Bacteria,1TPRP@1239|Firmicutes,248N7@186801|Clostridia	186801|Clostridia	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401,ko:K13820	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1,Bac_export_2
PNCOCPKN_02325	622312.ROSEINA2194_00966	3.95e-136	390.0	COG1684@1|root,COG1684@2|Bacteria,1TRB2@1239|Firmicutes,24ECW@186801|Clostridia	186801|Clostridia	N	flagellar biosynthetic protein FliR	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
PNCOCPKN_02326	585394.RHOM_07030	6.88e-46	149.0	COG1987@1|root,COG1987@2|Bacteria,1VEHF@1239|Firmicutes,24QJR@186801|Clostridia	186801|Clostridia	N	Flagellar biosynthetic protein FliQ	fliQ	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
PNCOCPKN_02327	585394.RHOM_07025	4.76e-119	350.0	COG1338@1|root,COG1338@2|Bacteria,1TPIE@1239|Firmicutes,2487C@186801|Clostridia	186801|Clostridia	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
PNCOCPKN_02328	622312.ROSEINA2194_00963	2.66e-37	130.0	COG3190@1|root,COG3190@2|Bacteria,1VCEI@1239|Firmicutes,25FCZ@186801|Clostridia	186801|Clostridia	N	Flagellar biosynthesis protein, FliO	-	-	-	ko:K02418	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliO
PNCOCPKN_02329	585394.RHOM_07015	4.64e-76	227.0	COG2197@1|root,COG2197@2|Bacteria,1UIGG@1239|Firmicutes,25EMX@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
PNCOCPKN_02330	585394.RHOM_07010	6.25e-191	540.0	COG1776@1|root,COG1886@1|root,COG1776@2|Bacteria,COG1886@2|Bacteria,1TPT8@1239|Firmicutes,24821@186801|Clostridia	186801|Clostridia	N	Flagellar motor switch protein flin	fliN	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	CheC,FliMN_C
PNCOCPKN_02331	585394.RHOM_07005	3.2e-203	566.0	COG1868@1|root,COG1868@2|Bacteria,1TPTM@1239|Firmicutes,24AGV@186801|Clostridia	186801|Clostridia	N	flagellar motor switch protein FliM	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
PNCOCPKN_02332	585394.RHOM_07000	3.43e-66	207.0	2AHM3@1|root,317YZ@2|Bacteria,1V80Z@1239|Firmicutes,24M4F@186801|Clostridia	186801|Clostridia	S	Controls the rotational direction of flagella during chemotaxis	-	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
PNCOCPKN_02333	585394.RHOM_06995	2.87e-111	329.0	COG1360@1|root,COG1360@2|Bacteria,1V8KE@1239|Firmicutes,24GQQ@186801|Clostridia	186801|Clostridia	N	PFAM OmpA MotB domain protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
PNCOCPKN_02334	585394.RHOM_06990	6.43e-138	395.0	COG1291@1|root,COG1291@2|Bacteria,1TRH1@1239|Firmicutes,24AEJ@186801|Clostridia	186801|Clostridia	N	PFAM MotA TolQ ExbB proton channel	motA	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
PNCOCPKN_02335	1235790.C805_02008	5.92e-24	92.0	COG1582@1|root,COG1582@2|Bacteria,1VKHB@1239|Firmicutes,24RWI@186801|Clostridia,25XPE@186806|Eubacteriaceae	186801|Clostridia	N	Flagellar protein (FlbD)	flbD	-	-	ko:K02385	-	-	-	-	ko00000,ko02035	-	-	-	FlbD
PNCOCPKN_02336	585394.RHOM_06985	1.08e-228	650.0	COG1749@1|root,COG1749@2|Bacteria,1UHS7@1239|Firmicutes,247ZT@186801|Clostridia	186801|Clostridia	N	basal body rod protein	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
PNCOCPKN_02337	585394.RHOM_06980	3.05e-55	176.0	2E35U@1|root,32Y5R@2|Bacteria,1VEH9@1239|Firmicutes,24R2S@186801|Clostridia	186801|Clostridia	N	TIGRFAM flagellar operon protein	flg	-	-	-	-	-	-	-	-	-	-	-	Flagellar_put
PNCOCPKN_02338	585394.RHOM_06975	1.01e-79	247.0	COG1843@1|root,COG1843@2|Bacteria,1VF85@1239|Firmicutes,24QKD@186801|Clostridia	186801|Clostridia	N	Required for flagellar hook formation. May act as a scaffolding protein	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD
PNCOCPKN_02339	585394.RHOM_06970	1.18e-88	287.0	COG3144@1|root,COG3144@2|Bacteria,1V4YB@1239|Firmicutes,24JMD@186801|Clostridia	186801|Clostridia	N	Flagellar hook-length control protein	fliK	-	-	ko:K02414	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_hook
PNCOCPKN_02340	585394.RHOM_06965	1.14e-106	318.0	28H98@1|root,2Z7M1@2|Bacteria,1TRE9@1239|Firmicutes,24F21@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MgtE_N
PNCOCPKN_02341	585394.RHOM_06960	1.36e-59	188.0	COG2882@1|root,COG2882@2|Bacteria,1VK96@1239|Firmicutes,24RWK@186801|Clostridia	186801|Clostridia	NOU	flagellar export protein FliJ	fliJ	-	-	ko:K02413	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliJ
PNCOCPKN_02342	622312.ROSEINA2194_00945	4.32e-270	744.0	COG1157@1|root,COG1157@2|Bacteria,1TP0R@1239|Firmicutes,25E6B@186801|Clostridia	186801|Clostridia	NU	Flagellar protein export ATPase FliI	fliI	-	3.6.3.14	ko:K02412,ko:K03224	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko01000,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
PNCOCPKN_02343	585394.RHOM_06950	1.92e-53	181.0	COG1317@1|root,COG1317@2|Bacteria,1V7UQ@1239|Firmicutes	1239|Firmicutes	NU	Flagellar assembly protein FliH	-	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
PNCOCPKN_02344	585394.RHOM_06945	1.56e-213	593.0	COG1536@1|root,COG1536@2|Bacteria,1TP01@1239|Firmicutes,2480B@186801|Clostridia	186801|Clostridia	N	Flagellar motor switch protein flig	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
PNCOCPKN_02345	622312.ROSEINA2194_00942	1.77e-227	644.0	COG1766@1|root,COG1766@2|Bacteria,1TRK0@1239|Firmicutes,2498Q@186801|Clostridia	186801|Clostridia	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
PNCOCPKN_02346	622312.ROSEINA2194_00941	9.85e-41	137.0	COG1677@1|root,COG1677@2|Bacteria	2|Bacteria	N	Flagellar hook-basal body complex protein FliE	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
PNCOCPKN_02347	585394.RHOM_06925	1.29e-79	238.0	COG1558@1|root,COG1558@2|Bacteria,1V6NB@1239|Firmicutes,24JJW@186801|Clostridia	186801|Clostridia	N	Belongs to the flagella basal body rod proteins family	flgC	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
PNCOCPKN_02348	622312.ROSEINA2194_00939	3.78e-58	183.0	COG1815@1|root,COG1815@2|Bacteria,1VEUZ@1239|Firmicutes,24RBE@186801|Clostridia	186801|Clostridia	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	flgB	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
PNCOCPKN_02349	622312.ROSEINA2194_00938	8.66e-155	462.0	COG0550@1|root,COG4465@1|root,COG0550@2|Bacteria,COG4465@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
PNCOCPKN_02350	622312.ROSEINA2194_00938	0.0	1188.0	COG0550@1|root,COG4465@1|root,COG0550@2|Bacteria,COG4465@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
PNCOCPKN_02351	622312.ROSEINA2194_00937	7.51e-144	418.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia	186801|Clostridia	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
PNCOCPKN_02352	585394.RHOM_06900	5.51e-233	656.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia	186801|Clostridia	O	chelatase subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
PNCOCPKN_02353	622312.ROSEINA2194_00935	3.41e-95	282.0	COG1191@1|root,COG1191@2|Bacteria,1TPJ5@1239|Firmicutes,247XH@186801|Clostridia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigK	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
PNCOCPKN_02354	622312.ROSEINA2194_00934	2.18e-138	399.0	COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,249AH@186801|Clostridia	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD_2	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
PNCOCPKN_02355	585394.RHOM_06885	9.4e-100	294.0	2943S@1|root,2ZRIE@2|Bacteria,1V3J6@1239|Firmicutes,24HEP@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	KatE	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02356	585394.RHOM_06880	1.17e-251	713.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
PNCOCPKN_02357	585394.RHOM_06865	9.22e-46	149.0	2E3QR@1|root,32YNK@2|Bacteria,1VENX@1239|Firmicutes,24QVR@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
PNCOCPKN_02358	622312.ROSEINA2194_00929	0.0	892.0	COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,2484I@186801|Clostridia	186801|Clostridia	L	DNA helicase	yjcD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
PNCOCPKN_02359	585394.RHOM_06855	0.0	922.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
PNCOCPKN_02360	585394.RHOM_06850	1.66e-215	617.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
PNCOCPKN_02361	585394.RHOM_06845	1.08e-199	566.0	COG2182@1|root,COG2182@2|Bacteria,1VRPK@1239|Firmicutes,24Y63@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
PNCOCPKN_02363	622312.ROSEINA2194_00922	3.08e-33	117.0	2E34J@1|root,32Y4N@2|Bacteria,1VESM@1239|Firmicutes,24QZX@186801|Clostridia	186801|Clostridia	S	COG NOG18028 non supervised orthologous group	cotJB	-	-	ko:K06333	-	-	-	-	ko00000	-	-	-	CotJB
PNCOCPKN_02364	585394.RHOM_06825	3.06e-137	389.0	COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,247YJ@186801|Clostridia	186801|Clostridia	P	PFAM Manganese containing catalase	cotJC	-	-	ko:K06334	-	-	-	-	ko00000	-	-	-	Mn_catalase
PNCOCPKN_02365	585394.RHOM_06810	1.1e-157	456.0	28KI7@1|root,2ZA3H@2|Bacteria,1V07J@1239|Firmicutes,24EVH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02366	622312.ROSEINA2194_00916	8.58e-72	228.0	2B4WY@1|root,31XPQ@2|Bacteria,1V739@1239|Firmicutes,24IHF@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02367	585394.RHOM_06800	2.23e-177	508.0	28MVQ@1|root,2ZB38@2|Bacteria,1UUTH@1239|Firmicutes,24AV8@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02368	585394.RHOM_06795	0.0	1230.0	2C1EE@1|root,2Z86R@2|Bacteria,1TS39@1239|Firmicutes,24ABS@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	Rnd	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02369	585394.RHOM_06790	2.99e-233	645.0	COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia	186801|Clostridia	E	PFAM Aminotransferase class I and II	hisC	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
PNCOCPKN_02371	622312.ROSEINA2194_01367	0.0	956.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
PNCOCPKN_02372	585394.RHOM_09335	4.86e-55	172.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia	186801|Clostridia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
PNCOCPKN_02373	585394.RHOM_09340	1.44e-181	515.0	COG1073@1|root,COG1073@2|Bacteria,1UF81@1239|Firmicutes,24BZ7@186801|Clostridia	186801|Clostridia	H	Protein of unknown function (DUF2974)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2974
PNCOCPKN_02374	622312.ROSEINA2194_01364	6.6e-112	329.0	COG0561@1|root,COG0561@2|Bacteria,1TSZZ@1239|Firmicutes,25B6T@186801|Clostridia	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
PNCOCPKN_02375	585394.RHOM_09350	9.36e-300	823.0	COG1143@1|root,COG4624@1|root,COG1143@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia	186801|Clostridia	C	Iron only hydrogenase large subunit, C-terminal domain	-	-	1.12.7.2	ko:K00533	-	-	R00019	-	ko00000,ko01000	-	-	-	Fe_hyd_lg_C,Fer4
PNCOCPKN_02376	483218.BACPEC_02951	1.96e-126	375.0	COG2199@1|root,COG2199@2|Bacteria,1VBH6@1239|Firmicutes,24P8P@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
PNCOCPKN_02377	483218.BACPEC_02952	4.32e-83	261.0	COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,249J1@186801|Clostridia,26BFC@186813|unclassified Clostridiales	186801|Clostridia	S	Serine hydrolase (FSH1)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	FSH1,Hydrolase_4,Peptidase_S9
PNCOCPKN_02378	1235792.C808_04581	6.6e-34	139.0	2CB93@1|root,30P4I@2|Bacteria,1V581@1239|Firmicutes,24IR0@186801|Clostridia,27NVE@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02379	585394.RHOM_10175	0.0	1102.0	COG2217@1|root,COG2217@2|Bacteria,1TPB8@1239|Firmicutes,247RZ@186801|Clostridia	186801|Clostridia	P	heavy metal translocating P-type ATPase	copA_1	-	-	ko:K12950	-	-	-	-	ko00000,ko01000	3.A.3.32	-	-	E1-E2_ATPase,Hydrolase
PNCOCPKN_02380	411902.CLOBOL_05591	2.48e-34	121.0	2E5VW@1|root,330JY@2|Bacteria,1VEZ5@1239|Firmicutes,24R14@186801|Clostridia,2218J@1506553|Lachnoclostridium	186801|Clostridia	S	H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02381	622312.ROSEINA2194_01772	0.0	972.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
PNCOCPKN_02382	585394.RHOM_03480	3.73e-40	133.0	COG2608@1|root,COG2608@2|Bacteria,1VEM6@1239|Firmicutes,24R22@186801|Clostridia	186801|Clostridia	P	Heavy metal-associated domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HMA
PNCOCPKN_02383	622312.ROSEINA2194_01770	1.55e-65	201.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	ziaR	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
PNCOCPKN_02384	903814.ELI_3973	1.48e-71	225.0	COG0300@1|root,COG0300@2|Bacteria,1V3UX@1239|Firmicutes,25B0Y@186801|Clostridia,25WEG@186806|Eubacteriaceae	186801|Clostridia	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
PNCOCPKN_02385	585394.RHOM_13950	1.42e-56	176.0	COG3668@1|root,COG3668@2|Bacteria,1VGR8@1239|Firmicutes,24KGA@186801|Clostridia	186801|Clostridia	S	addiction module toxin, RelE StbE family	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
PNCOCPKN_02386	585394.RHOM_13955	1.29e-49	157.0	COG2161@1|root,COG2161@2|Bacteria,1VA5D@1239|Firmicutes,24NDD@186801|Clostridia	186801|Clostridia	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
PNCOCPKN_02387	585394.RHOM_13985	6.35e-69	210.0	COG0745@1|root,COG0745@2|Bacteria,1VCPH@1239|Firmicutes,24MRK@186801|Clostridia	186801|Clostridia	KT	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
PNCOCPKN_02388	1235793.C809_03218	1.98e-104	307.0	COG1136@1|root,COG1136@2|Bacteria,1TP5M@1239|Firmicutes,24BH7@186801|Clostridia,27KIX@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
PNCOCPKN_02389	1235790.C805_01118	6.33e-45	160.0	COG0577@1|root,COG0577@2|Bacteria,1TPSE@1239|Firmicutes,24BUY@186801|Clostridia,25VFD@186806|Eubacteriaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PNCOCPKN_02390	397287.C807_02475	7.59e-54	169.0	COG2963@1|root,COG2963@2|Bacteria,1V9ZX@1239|Firmicutes,24P3X@186801|Clostridia,27RZY@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
PNCOCPKN_02391	1235793.C809_03029	4.53e-153	435.0	COG2801@1|root,COG2801@2|Bacteria,1TPEH@1239|Firmicutes,24DNX@186801|Clostridia,27T8M@186928|unclassified Lachnospiraceae	186801|Clostridia	L	DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
PNCOCPKN_02392	585394.RHOM_14030	1.38e-101	301.0	COG0582@1|root,COG0582@2|Bacteria,1TSN5@1239|Firmicutes,248E3@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
PNCOCPKN_02393	622312.ROSEINA2194_00803	0.0	869.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia	186801|Clostridia	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
PNCOCPKN_02394	1235790.C805_03587	5.42e-118	357.0	COG2340@1|root,COG2340@2|Bacteria,1V1IM@1239|Firmicutes,24GB5@186801|Clostridia,25WC7@186806|Eubacteriaceae	186801|Clostridia	N	hydrolase, family 25	-	-	-	-	-	-	-	-	-	-	-	-	CAP,SLH
PNCOCPKN_02395	585394.RHOM_14040	3.88e-42	139.0	2C5I7@1|root,330HE@2|Bacteria,1VJU8@1239|Firmicutes,24SCX@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.75	-	-	-	-	-	-	-	-	-	-	-	-	DUF4321
PNCOCPKN_02396	585394.RHOM_02665	8.93e-164	462.0	COG3833@1|root,COG3833@2|Bacteria,1TRB7@1239|Firmicutes,24DNI@186801|Clostridia	186801|Clostridia	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
PNCOCPKN_02397	585394.RHOM_02660	1.78e-33	126.0	COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,247MA@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
PNCOCPKN_02398	1256908.HMPREF0373_03376	9.56e-75	225.0	COG5658@1|root,COG5658@2|Bacteria,1VB6E@1239|Firmicutes,24MSY@186801|Clostridia,25XHU@186806|Eubacteriaceae	186801|Clostridia	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	SdpI
PNCOCPKN_02399	518637.EUBIFOR_00314	3.44e-29	104.0	2BEFR@1|root,33CRA@2|Bacteria,1VQ4D@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02400	622312.ROSEINA2194_02852	1.35e-176	498.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia	186801|Clostridia	C	Belongs to the LDH MDH superfamily. LDH family	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
PNCOCPKN_02401	585394.RHOM_14045	4.24e-78	235.0	COG1846@1|root,COG1846@2|Bacteria,1V6GY@1239|Firmicutes,24HTB@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
PNCOCPKN_02403	622312.ROSEINA2194_00805	1.28e-166	473.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
PNCOCPKN_02404	585394.RHOM_14055	0.0	941.0	COG0777@1|root,COG0825@1|root,COG0777@2|Bacteria,COG0825@2|Bacteria,1TP4U@1239|Firmicutes,248QK@186801|Clostridia	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20740	ACCA,Carboxyl_trans
PNCOCPKN_02405	622312.ROSEINA2194_00807	4.38e-80	239.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,24JAW@186801|Clostridia	186801|Clostridia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
PNCOCPKN_02406	585394.RHOM_14065	1.84e-243	675.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
PNCOCPKN_02407	476272.RUMHYD_01858	1.07e-115	338.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,3XYM7@572511|Blautia	186801|Clostridia	IQ	Psort location Cytoplasmic, score	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
PNCOCPKN_02408	622312.ROSEINA2194_00810	4.35e-152	435.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia	186801|Clostridia	I	malonyl coa-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
PNCOCPKN_02409	585394.RHOM_14080	3.03e-180	507.0	COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,24831@186801|Clostridia	186801|Clostridia	S	reductase II	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iHN637.CLJU_RS20775	NMO
PNCOCPKN_02410	622312.ROSEINA2194_00812	4.47e-35	120.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
PNCOCPKN_02411	1408312.JNJS01000004_gene2495	7.95e-149	425.0	COG1533@1|root,COG1533@2|Bacteria,1TSS2@1239|Firmicutes,248SB@186801|Clostridia,3NI14@46205|Pseudobutyrivibrio	186801|Clostridia	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
PNCOCPKN_02412	397290.C810_02525	4.04e-62	195.0	COG1670@1|root,COG1670@2|Bacteria,1UJXM@1239|Firmicutes,25FDP@186801|Clostridia,27P0P@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
PNCOCPKN_02413	1160721.RBI_I01804	2.66e-56	179.0	COG1310@1|root,COG1310@2|Bacteria,1V6TY@1239|Firmicutes,24JI8@186801|Clostridia,3WJ1M@541000|Ruminococcaceae	186801|Clostridia	S	Mov34 MPN PAD-1 family	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
PNCOCPKN_02414	483218.BACPEC_01201	4.81e-183	510.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,25CJC@186801|Clostridia,269P8@186813|unclassified Clostridiales	186801|Clostridia	H	ThiF family	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
PNCOCPKN_02415	483218.BACPEC_01202	2.65e-29	105.0	COG2104@1|root,COG2104@2|Bacteria,1VFJR@1239|Firmicutes,24SEU@186801|Clostridia	186801|Clostridia	H	thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
PNCOCPKN_02416	483218.BACPEC_01203	1.81e-42	141.0	COG0526@1|root,COG0526@2|Bacteria,1UHN6@1239|Firmicutes,25FT1@186801|Clostridia	186801|Clostridia	O	Thioredoxin	trxA1	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
PNCOCPKN_02417	483218.BACPEC_01204	2.7e-45	147.0	COG0425@1|root,COG0425@2|Bacteria,1VBET@1239|Firmicutes,24NV0@186801|Clostridia	186801|Clostridia	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
PNCOCPKN_02418	483218.BACPEC_01205	3.26e-169	477.0	COG2221@1|root,COG2221@2|Bacteria,1TR7P@1239|Firmicutes,2493K@186801|Clostridia,269QP@186813|unclassified Clostridiales	186801|Clostridia	C	Nitrite/Sulfite reductase ferredoxin-like half domain	-	-	-	ko:K00385	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	Fer4,Fer4_7,NIR_SIR,NIR_SIR_ferr
PNCOCPKN_02419	483218.BACPEC_01206	1.14e-232	647.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,2683I@186813|unclassified Clostridiales	186801|Clostridia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
PNCOCPKN_02420	526218.Sterm_3395	2.61e-142	420.0	COG0534@1|root,COG0534@2|Bacteria,37890@32066|Fusobacteria	32066|Fusobacteria	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PNCOCPKN_02421	1392491.JIAE01000001_gene482	4.54e-23	95.5	COG1846@1|root,COG1846@2|Bacteria,1TTMF@1239|Firmicutes,25MX0@186801|Clostridia,3WMH1@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
PNCOCPKN_02422	1095750.HMPREF9970_2627	2.55e-68	217.0	COG2230@1|root,COG2230@2|Bacteria,1TSG4@1239|Firmicutes,248GV@186801|Clostridia,1HW50@1164882|Lachnoanaerobaculum	186801|Clostridia	H	Protein of unknown function (DUF1698)	cfa	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
PNCOCPKN_02423	515620.EUBELI_20196	3.71e-128	365.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249VD@186801|Clostridia,25WCD@186806|Eubacteriaceae	186801|Clostridia	F	Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
PNCOCPKN_02424	515620.EUBELI_20197	2.44e-302	827.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,25VG0@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PNCOCPKN_02425	585394.RHOM_00965	1.57e-70	214.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
PNCOCPKN_02426	585394.RHOM_00960	7.98e-105	305.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
PNCOCPKN_02427	622312.ROSEINA2194_01982	7.27e-157	441.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
PNCOCPKN_02428	397290.C810_03360	9.01e-89	261.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,27M6H@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
PNCOCPKN_02429	585394.RHOM_00945	3.44e-117	335.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia	186801|Clostridia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
PNCOCPKN_02430	140626.JHWB01000009_gene1219	2.28e-27	100.0	COG0690@1|root,COG0690@2|Bacteria,1VH7Y@1239|Firmicutes,24RJ1@186801|Clostridia	186801|Clostridia	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
PNCOCPKN_02431	585394.RHOM_00930	1.03e-160	468.0	COG1345@1|root,COG1345@2|Bacteria,1U3CE@1239|Firmicutes,24B6P@186801|Clostridia	186801|Clostridia	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliD_C,FliD_N
PNCOCPKN_02432	585394.RHOM_00925	2.55e-245	678.0	COG4641@1|root,COG4641@2|Bacteria,1TR7G@1239|Firmicutes,24ATN@186801|Clostridia	186801|Clostridia	S	DUF based on E. rectale Gene description (DUF3880)	-	-	-	ko:K06320	-	-	-	-	ko00000	-	-	-	DUF3880,Glyco_trans_1_2
PNCOCPKN_02433	585394.RHOM_00920	6.02e-221	618.0	COG4641@1|root,COG4641@2|Bacteria,1V0EG@1239|Firmicutes,24DZB@186801|Clostridia	186801|Clostridia	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
PNCOCPKN_02434	622312.ROSEINA2194_00427	4.5e-282	782.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
PNCOCPKN_02435	585394.RHOM_00900	8.66e-166	476.0	COG0457@1|root,COG0463@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,1TSF5@1239|Firmicutes,25B5G@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2,TPR_2,TPR_7,TPR_8
PNCOCPKN_02436	500632.CLONEX_01546	2.13e-48	173.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
PNCOCPKN_02437	1122134.KB893650_gene460	1.95e-13	74.7	28MIE@1|root,2ZAV6@2|Bacteria,1R51M@1224|Proteobacteria,1S0ZX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02438	622312.ROSEINA2194_00405	1.5e-176	504.0	COG1216@1|root,COG1216@2|Bacteria,1V5UZ@1239|Firmicutes,24J2K@186801|Clostridia	186801|Clostridia	S	Glycosyltransferase like family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_5
PNCOCPKN_02439	585394.RHOM_00820	1.23e-107	320.0	COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia	186801|Clostridia	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
PNCOCPKN_02440	622312.ROSEINA2194_00398	3.83e-156	451.0	COG4641@1|root,COG4641@2|Bacteria,1V3QP@1239|Firmicutes,24I06@186801|Clostridia	186801|Clostridia	S	DUF based on E. rectale Gene description (DUF3880)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3880,Glyco_trans_1_2
PNCOCPKN_02441	1408287.AXUR01000004_gene1972	1.14e-54	182.0	COG1045@1|root,COG1045@2|Bacteria	2|Bacteria	E	serine acetyltransferase	-	-	2.3.1.209,2.3.1.30	ko:K00640,ko:K21379	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
PNCOCPKN_02442	1235790.C805_03281	1.36e-147	426.0	COG0535@1|root,COG0535@2|Bacteria,1V348@1239|Firmicutes,24GVU@186801|Clostridia,25X0M@186806|Eubacteriaceae	186801|Clostridia	C	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
PNCOCPKN_02443	1410618.JNKI01000016_gene1798	2.49e-177	506.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4H4G5@909932|Negativicutes	909932|Negativicutes	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
PNCOCPKN_02444	1408423.JHYA01000004_gene2353	8.4e-199	561.0	COG1086@1|root,COG1086@2|Bacteria,1TQRB@1239|Firmicutes,4H6TB@909932|Negativicutes	909932|Negativicutes	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_2
PNCOCPKN_02445	1235790.C805_03282	1.4e-275	771.0	COG0028@1|root,COG0028@2|Bacteria,1V0AN@1239|Firmicutes,24EVV@186801|Clostridia,25YBC@186806|Eubacteriaceae	186801|Clostridia	EH	Thiamine pyrophosphate enzyme, central domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PNCOCPKN_02446	1511.CLOST_0365	6.78e-111	333.0	COG0517@1|root,COG1208@1|root,COG0517@2|Bacteria,COG1208@2|Bacteria,1TRKP@1239|Firmicutes,248ZS@186801|Clostridia,25SUJ@186804|Peptostreptococcaceae	186801|Clostridia	JM	Nucleotidyl transferase	-	-	2.7.7.71	ko:K15669	ko00540,map00540	-	R09772	RC00002	ko00000,ko00001,ko01000	-	-	-	CBS,NTP_transferase
PNCOCPKN_02447	1235802.C823_00453	1.83e-97	295.0	COG0451@1|root,COG0451@2|Bacteria,1VTMC@1239|Firmicutes,24JCJ@186801|Clostridia,25YF6@186806|Eubacteriaceae	186801|Clostridia	GM	RmlD substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
PNCOCPKN_02449	411470.RUMGNA_01234	2.14e-152	435.0	COG3385@1|root,COG3385@2|Bacteria,1UNGW@1239|Firmicutes,24BMP@186801|Clostridia,3Y1GW@572511|Blautia	186801|Clostridia	L	COG NOG14195 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
PNCOCPKN_02450	515622.bpr_I0429	1.72e-158	457.0	COG0381@1|root,COG0381@2|Bacteria,1TQKQ@1239|Firmicutes,24A0H@186801|Clostridia,4BWI3@830|Butyrivibrio	186801|Clostridia	M	UDP-N-acetylglucosamine 2-epimerase	neuC	-	3.2.1.184,5.1.3.14	ko:K01791,ko:K18429	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R10187	RC00005,RC00288,RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
PNCOCPKN_02451	1280668.ATVT01000017_gene1573	3.88e-156	447.0	COG2089@1|root,COG2089@2|Bacteria,1TS09@1239|Firmicutes,249DN@186801|Clostridia,4BYM4@830|Butyrivibrio	186801|Clostridia	M	SAF	neuB	-	2.5.1.101,2.5.1.56	ko:K01654,ko:K18430	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R10304	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
PNCOCPKN_02452	547045.NEISICOT_02331	3.8e-67	215.0	COG0223@1|root,COG0223@2|Bacteria,1MWH1@1224|Proteobacteria,2VKAI@28216|Betaproteobacteria,2KTGT@206351|Neisseriales	206351|Neisseriales	J	Formyl transferase	-	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_N
PNCOCPKN_02453	658655.HMPREF0988_00172	0.000902	41.2	COG0300@1|root,COG0300@2|Bacteria,1UZHA@1239|Firmicutes,248C8@186801|Clostridia,27U0G@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
PNCOCPKN_02454	622312.ROSEINA2194_02492	2.1e-172	484.0	COG0395@1|root,COG0395@2|Bacteria,1TS0R@1239|Firmicutes,248UX@186801|Clostridia	186801|Clostridia	P	ABC-type sugar transport system, permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
PNCOCPKN_02455	622312.ROSEINA2194_02493	2.03e-193	540.0	COG1175@1|root,COG1175@2|Bacteria,1TS63@1239|Firmicutes,2489M@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport systems permease components	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
PNCOCPKN_02456	622312.ROSEINA2194_02494	9.96e-243	682.0	COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
PNCOCPKN_02457	585394.RHOM_05815	1.57e-154	436.0	COG2207@1|root,COG2207@2|Bacteria,1UZ5U@1239|Firmicutes,24DJM@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC
PNCOCPKN_02458	658088.HMPREF0987_01443	0.0	1325.0	COG3459@1|root,COG3459@2|Bacteria,1UYFP@1239|Firmicutes,24A8A@186801|Clostridia,27J08@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36
PNCOCPKN_02459	658088.HMPREF0987_01444	0.0	1462.0	COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,248YP@186801|Clostridia,27I5Y@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Putative carbohydrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36
PNCOCPKN_02460	585394.RHOM_10590	6.14e-36	123.0	COG2608@1|root,COG2608@2|Bacteria,1VETC@1239|Firmicutes,24QJU@186801|Clostridia	186801|Clostridia	P	mercury ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	HMA
PNCOCPKN_02461	1304866.K413DRAFT_2073	9.95e-66	204.0	COG0735@1|root,COG0735@2|Bacteria,1V6DP@1239|Firmicutes,24K9H@186801|Clostridia,36IEH@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
PNCOCPKN_02462	1235799.C818_03332	7.94e-17	72.4	2C6KI@1|root,33J10@2|Bacteria,1VKBK@1239|Firmicutes,24UUY@186801|Clostridia,27Q8P@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Virus attachment protein p12 family	-	-	-	-	-	-	-	-	-	-	-	-	P12
PNCOCPKN_02463	585394.RHOM_03455	0.0	1303.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
PNCOCPKN_02464	585394.RHOM_03450	7.15e-43	140.0	COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,24QKE@186801|Clostridia	186801|Clostridia	P	Fe2 transport system protein A	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
PNCOCPKN_02465	1226325.HMPREF1548_05939	6.25e-36	122.0	COG1918@1|root,COG1918@2|Bacteria,1VEYA@1239|Firmicutes,24QKX@186801|Clostridia,36MP8@31979|Clostridiaceae	186801|Clostridia	P	Fe2 transport system protein A	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
PNCOCPKN_02466	658086.HMPREF0994_06533	0.0	961.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,27IHI@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolases family 2	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
PNCOCPKN_02467	1274374.CBLK010000070_gene1204	3.35e-233	696.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,4HB2V@91061|Bacilli,26SFU@186822|Paenibacillaceae	1239|Firmicutes	G	Alpha-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
PNCOCPKN_02469	1298920.KI911353_gene1797	3.04e-134	389.0	COG0395@1|root,COG0395@2|Bacteria,1V2Q1@1239|Firmicutes,24A8E@186801|Clostridia,2202Q@1506553|Lachnoclostridium	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
PNCOCPKN_02470	610130.Closa_1668	8.67e-136	394.0	COG1175@1|root,COG1175@2|Bacteria,1V0JI@1239|Firmicutes,25C5R@186801|Clostridia,2200H@1506553|Lachnoclostridium	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
PNCOCPKN_02471	1298920.KI911353_gene1795	3.66e-171	496.0	COG1653@1|root,COG1653@2|Bacteria,1V5R7@1239|Firmicutes,25BSW@186801|Clostridia,221PP@1506553|Lachnoclostridium	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
PNCOCPKN_02472	1345695.CLSA_c30480	3.9e-77	236.0	COG0572@1|root,COG0572@2|Bacteria,1V1DZ@1239|Firmicutes,24FY8@186801|Clostridia,36HX9@31979|Clostridiaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PRK
PNCOCPKN_02473	632245.CLP_2202	4.45e-57	184.0	298ZI@1|root,2ZW3A@2|Bacteria,1V7FU@1239|Firmicutes,24ID8@186801|Clostridia,36KW8@31979|Clostridiaceae	186801|Clostridia	S	ECF transporter, substrate-specific component	-	-	-	ko:K16788	-	-	-	-	ko00000,ko02000	2.A.88.5	-	-	ECF_trnsprt
PNCOCPKN_02474	545243.BAEV01000034_gene1723	7.39e-17	85.1	COG0655@1|root,COG0655@2|Bacteria,1UI36@1239|Firmicutes,247R8@186801|Clostridia,36EYY@31979|Clostridiaceae	186801|Clostridia	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
PNCOCPKN_02477	537013.CLOSTMETH_02259	1.19e-89	277.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,248QD@186801|Clostridia,3WHHC@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	sagG	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
PNCOCPKN_02479	1499502.EV12_2779	9.36e-21	101.0	COG1216@1|root,COG1216@2|Bacteria,1G1PB@1117|Cyanobacteria,1MKSQ@1212|Prochloraceae	1117|Cyanobacteria	S	Alternative locus ID	wcaA	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PNCOCPKN_02482	869213.JCM21142_31077	1.85e-69	219.0	COG1136@1|root,COG1136@2|Bacteria,4NFDW@976|Bacteroidetes,47KMI@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PNCOCPKN_02483	1379270.AUXF01000006_gene300	3.15e-40	146.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,1ZT4Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
PNCOCPKN_02484	290397.Adeh_1214	7.3e-28	119.0	COG4990@1|root,COG4990@2|Bacteria,1MVC4@1224|Proteobacteria,42RB3@68525|delta/epsilon subdivisions,2WMW4@28221|Deltaproteobacteria,2Z183@29|Myxococcales	28221|Deltaproteobacteria	S	Butirosin biosynthesis protein H, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BtrH_N,DUF4872
PNCOCPKN_02486	935837.JAEK01000008_gene3474	4.08e-105	323.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,1ZD02@1386|Bacillus	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
PNCOCPKN_02487	1157490.EL26_16395	4.69e-21	86.3	COG0236@1|root,COG0236@2|Bacteria,1VP03@1239|Firmicutes,4HSA8@91061|Bacilli	91061|Bacilli	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
PNCOCPKN_02488	1123372.AUIT01000014_gene1606	8.41e-73	229.0	COG1028@1|root,COG1028@2|Bacteria,2GH4K@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
PNCOCPKN_02489	558169.AGAV01000005_gene2402	1.02e-45	169.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458,ko:K14660	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iSB619.SA_RS04785	Ketoacyl-synt_C,ketoacyl-synt
PNCOCPKN_02490	458817.Shal_2551	1.37e-20	102.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RMGJ@1236|Gammaproteobacteria,2Q9YU@267890|Shewanellaceae	1236|Gammaproteobacteria	Q	NAD(P)-binding Rossmann-like domain	-	-	1.3.99.23	ko:K09516	ko00830,map00830	-	R07163	RC01835	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,FAD_binding_6,NAD_binding_1,NAD_binding_8
PNCOCPKN_02491	1408422.JHYF01000003_gene932	7.44e-20	87.0	COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,24NBX@186801|Clostridia,36JT8@31979|Clostridiaceae	186801|Clostridia	S	acyl-CoA thioester hydrolase, YbgC YbaW family	FcbC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
PNCOCPKN_02493	237368.SCABRO_03001	1.19e-35	140.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	-	-	1.3.1.101,1.3.1.111,1.3.1.83,1.3.7.11	ko:K10960,ko:K17830	ko00564,ko00860,ko00900,ko01100,ko01110,map00564,map00860,map00900,map01100,map01110	-	R02063,R08754,R08755,R08756,R10325,R10326,R10331,R11226,R11518	RC00212,RC00522,RC01823,RC03134	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
PNCOCPKN_02494	96561.Dole_0589	3.33e-65	219.0	COG1145@1|root,COG2006@1|root,COG1145@2|Bacteria,COG2006@2|Bacteria,1RABP@1224|Proteobacteria,42QQA@68525|delta/epsilon subdivisions,2WMRX@28221|Deltaproteobacteria,2MK55@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4
PNCOCPKN_02495	1293054.HSACCH_00639	3.61e-47	167.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,3WAGY@53433|Halanaerobiales	186801|Clostridia	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
PNCOCPKN_02496	1458462.JNLK01000001_gene369	3.12e-08	60.1	COG2091@1|root,COG2091@2|Bacteria,1VEYZ@1239|Firmicutes,24RQ3@186801|Clostridia,27PK6@186928|unclassified Lachnospiraceae	186801|Clostridia	H	4'-phosphopantetheinyl transferase superfamily	sfp	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
PNCOCPKN_02497	1235790.C805_02586	8.95e-228	645.0	COG0777@1|root,COG0825@1|root,COG0777@2|Bacteria,COG0825@2|Bacteria,1TP4U@1239|Firmicutes,248QK@186801|Clostridia,25V1B@186806|Eubacteriaceae	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20740	ACCA,Carboxyl_trans
PNCOCPKN_02498	1235802.C823_00220	2.78e-06	46.2	2DTTG@1|root,33MJV@2|Bacteria,1VKVF@1239|Firmicutes,254H5@186801|Clostridia,25Z3V@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02500	1410628.JNKS01000041_gene869	3.93e-242	671.0	COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,247ZX@186801|Clostridia,27TN8@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
PNCOCPKN_02502	622312.ROSEINA2194_03185	2.09e-310	847.0	COG0642@1|root,COG2205@2|Bacteria,1TS1G@1239|Firmicutes,248TF@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K20487	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
PNCOCPKN_02503	622312.ROSEINA2194_03184	5.26e-156	437.0	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,248WX@186801|Clostridia	186801|Clostridia	KT	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
PNCOCPKN_02504	411461.DORFOR_00395	1.39e-173	484.0	COG4200@1|root,COG4200@2|Bacteria,1V4AY@1239|Firmicutes,24EXR@186801|Clostridia,27W6N@189330|Dorea	186801|Clostridia	S	COG NOG31276 non supervised orthologous group	mutG	-	-	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC2_membrane_4
PNCOCPKN_02505	1256908.HMPREF0373_00092	4.81e-168	470.0	COG4200@1|root,COG4200@2|Bacteria,1TRRE@1239|Firmicutes,24AHY@186801|Clostridia,25ZJG@186806|Eubacteriaceae	186801|Clostridia	S	Lantibiotic protection ABC transporter permease subunit, MutE EpiE family	-	-	-	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC2_membrane_4
PNCOCPKN_02506	1256908.HMPREF0373_00091	9.33e-163	456.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,253U3@186801|Clostridia,25VRU@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00254,M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC_tran
PNCOCPKN_02507	1280698.AUJS01000042_gene3279	1.26e-115	333.0	COG2265@1|root,COG2265@2|Bacteria,1UK4G@1239|Firmicutes,24H6A@186801|Clostridia,27W5R@189330|Dorea	186801|Clostridia	J	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
PNCOCPKN_02508	483218.BACPEC_00659	9.74e-41	147.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,267VV@186813|unclassified Clostridiales	186801|Clostridia	L	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
PNCOCPKN_02509	411463.EUBVEN_02568	0.0	1146.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,25UYJ@186806|Eubacteriaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
PNCOCPKN_02510	515620.EUBELI_20651	6.37e-232	639.0	COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,24B0E@186801|Clostridia,25UVN@186806|Eubacteriaceae	186801|Clostridia	M	Choloylglycine hydrolase	cbh	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
PNCOCPKN_02511	483218.BACPEC_02237	3.54e-31	111.0	2F14R@1|root,33U60@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02512	483218.BACPEC_02238	1.26e-130	371.0	COG0558@1|root,COG0558@2|Bacteria,1V4YR@1239|Firmicutes,24FWZ@186801|Clostridia	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
PNCOCPKN_02513	411469.EUBHAL_01648	2.74e-250	687.0	2C2TA@1|root,2Z7T7@2|Bacteria,1TS53@1239|Firmicutes,248BA@186801|Clostridia,25W0J@186806|Eubacteriaceae	186801|Clostridia	S	CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
PNCOCPKN_02514	471875.RUMLAC_00940	4.74e-243	668.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,249HQ@186801|Clostridia,3WHVM@541000|Ruminococcaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
PNCOCPKN_02515	511680.BUTYVIB_02272	5.44e-155	435.0	COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,248B6@186801|Clostridia,4C156@830|Butyrivibrio	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PNCOCPKN_02516	585394.RHOM_13740	0.0	962.0	COG1502@1|root,COG1502@2|Bacteria,1TSN8@1239|Firmicutes,249G7@186801|Clostridia	186801|Clostridia	I	COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
PNCOCPKN_02517	411463.EUBVEN_02552	4.83e-93	272.0	28N68@1|root,2ZBB7@2|Bacteria,1UZ5P@1239|Firmicutes,24EZI@186801|Clostridia,25Y5Y@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02518	411463.EUBVEN_02551	0.0	877.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,25VD8@186806|Eubacteriaceae	186801|Clostridia	C	citrate synthase	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
PNCOCPKN_02519	585394.RHOM_13755	0.0	1054.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
PNCOCPKN_02520	500632.CLONEX_00605	4.68e-90	265.0	COG0073@1|root,COG0073@2|Bacteria,1V496@1239|Firmicutes,24J1W@186801|Clostridia	186801|Clostridia	J	Putative tRNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_bind
PNCOCPKN_02521	515620.EUBELI_20140	1.25e-117	337.0	COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,24ARG@186801|Clostridia,25UV0@186806|Eubacteriaceae	186801|Clostridia	S	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	-	-	-	-	-	-	-	-	-	Macro
PNCOCPKN_02522	1235793.C809_01807	1.15e-215	598.0	COG3039@1|root,COG3039@2|Bacteria,1UEG7@1239|Firmicutes,249X3@186801|Clostridia,27RX5@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase domain (DUF772)	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
PNCOCPKN_02528	585394.RHOM_02910	2.52e-219	613.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,247J3@186801|Clostridia	186801|Clostridia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
PNCOCPKN_02529	585394.RHOM_02915	0.0	1103.0	COG0664@1|root,COG0664@2|Bacteria,1TSX5@1239|Firmicutes,24A8U@186801|Clostridia	186801|Clostridia	T	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
PNCOCPKN_02531	585394.RHOM_02925	1.44e-36	126.0	COG0607@1|root,COG0607@2|Bacteria,1VGXK@1239|Firmicutes,24R46@186801|Clostridia	186801|Clostridia	P	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
PNCOCPKN_02532	585394.RHOM_02930	7.36e-258	709.0	COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,248MA@186801|Clostridia	186801|Clostridia	L	Belongs to the methyltransferase superfamily	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
PNCOCPKN_02533	622312.ROSEINA2194_01336	2.93e-316	872.0	COG4870@1|root,COG4870@2|Bacteria,1TVCW@1239|Firmicutes,248WA@186801|Clostridia	186801|Clostridia	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Cu_amine_oxidN1,Peptidase_C1,Rhodanese
PNCOCPKN_02534	622312.ROSEINA2194_01335	8.69e-166	473.0	COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia	186801|Clostridia	M	PFAM cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,Cu_amine_oxidN1
PNCOCPKN_02535	585394.RHOM_02950	1.12e-114	331.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
PNCOCPKN_02536	622312.ROSEINA2194_01333	1.1e-84	252.0	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,24MMK@186801|Clostridia	186801|Clostridia	S	Phosphoesterase	yfcE1	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
PNCOCPKN_02543	641107.CDLVIII_5672	5.62e-33	123.0	COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,248VX@186801|Clostridia,36DWD@31979|Clostridiaceae	186801|Clostridia	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
PNCOCPKN_02544	1280671.AUJH01000002_gene2226	1.05e-173	492.0	COG0310@1|root,COG0310@2|Bacteria,1TPEN@1239|Firmicutes,248S9@186801|Clostridia,4BW72@830|Butyrivibrio	186801|Clostridia	P	PDGLE domain	cbiM2	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
PNCOCPKN_02545	457396.CSBG_01568	1.9e-92	280.0	COG0619@1|root,COG0619@2|Bacteria,1U6XW@1239|Firmicutes,24EV0@186801|Clostridia,36FJU@31979|Clostridiaceae	186801|Clostridia	P	Cobalt ABC transporter, permease	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
PNCOCPKN_02546	1235792.C808_04034	1.06e-104	311.0	COG1122@1|root,COG1122@2|Bacteria,1TSSM@1239|Firmicutes,249KS@186801|Clostridia,27KCE@186928|unclassified Lachnospiraceae	186801|Clostridia	P	AAA domain, putative AbiEii toxin, Type IV TA system	cbiO	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
PNCOCPKN_02549	1329516.JPST01000014_gene643	1.03e-09	56.2	2DRWQ@1|root,33DF0@2|Bacteria	2|Bacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
PNCOCPKN_02550	1235793.C809_00938	1.29e-44	162.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
PNCOCPKN_02551	1235793.C809_00938	2.69e-23	100.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
PNCOCPKN_02552	1235792.C808_03552	3.84e-163	474.0	COG1373@1|root,COG1373@2|Bacteria,1UZD0@1239|Firmicutes,25EI0@186801|Clostridia,27M4F@186928|unclassified Lachnospiraceae	186801|Clostridia	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
PNCOCPKN_02556	350688.Clos_1301	9.24e-65	206.0	2FF0M@1|root,346Z2@2|Bacteria,1VZ03@1239|Firmicutes,252TW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02557	1123288.SOV_2c07040	1.74e-58	204.0	2F4WZ@1|root,33XJ2@2|Bacteria,1VVTM@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02558	665950.HMPREF1025_00004	1.11e-242	709.0	COG0507@1|root,COG0515@1|root,COG0507@2|Bacteria,COG0515@2|Bacteria,1VW06@1239|Firmicutes	1239|Firmicutes	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11
PNCOCPKN_02559	907348.TresaDRAFT_2301	0.0	1530.0	COG1061@1|root,COG1061@2|Bacteria	2|Bacteria	L	Type III restriction enzyme res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,ResIII,T5orf172
PNCOCPKN_02560	411483.FAEPRAA2165_01493	2.32e-158	465.0	COG0286@1|root,COG1002@1|root,COG0286@2|Bacteria,COG1002@2|Bacteria,1TT83@1239|Firmicutes,248CV@186801|Clostridia,3WIQA@541000|Ruminococcaceae	186801|Clostridia	L	restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I
PNCOCPKN_02561	1408324.JNJK01000008_gene1732	8.06e-139	401.0	COG1002@1|root,COG1002@2|Bacteria,1TT83@1239|Firmicutes,248CV@186801|Clostridia,27QT4@186928|unclassified Lachnospiraceae	186801|Clostridia	V	restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I
PNCOCPKN_02562	1235799.C818_01801	7.31e-106	309.0	COG1961@1|root,COG1961@2|Bacteria,1TQAX@1239|Firmicutes,24B05@186801|Clostridia,27M9D@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
PNCOCPKN_02563	1235793.C809_02296	5.09e-55	174.0	2DMY9@1|root,32UCT@2|Bacteria,1VAN7@1239|Firmicutes,24PHY@186801|Clostridia,27P1D@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
PNCOCPKN_02564	1235793.C809_02295	2.99e-188	538.0	COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia,27K2X@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
PNCOCPKN_02565	1235793.C809_02294	1.28e-22	94.0	29GWR@1|root,303UG@2|Bacteria,1TV9N@1239|Firmicutes,25A3B@186801|Clostridia,27PM3@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02566	1235793.C809_02293	1.59e-149	429.0	2DB8G@1|root,2Z7RT@2|Bacteria,1US26@1239|Firmicutes,24B9G@186801|Clostridia,27TVP@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02567	592026.GCWU0000282_001327	1.46e-252	701.0	COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,2495S@186801|Clostridia	186801|Clostridia	L	Virulence-associated protein E	-	-	-	-	-	-	-	-	-	-	-	-	VirE
PNCOCPKN_02568	1235793.C809_02291	1.24e-91	274.0	COG0358@1|root,COG0358@2|Bacteria,1UZ28@1239|Firmicutes,248N2@186801|Clostridia,27PAG@186928|unclassified Lachnospiraceae	186801|Clostridia	L	CHC2 zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHC2
PNCOCPKN_02569	552396.HMPREF0863_01960	5.93e-12	64.7	2C05I@1|root,2ZE0I@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02570	1235793.C809_02289	2.71e-239	660.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,27IQ7@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
PNCOCPKN_02571	1235793.C809_02288	5.5e-34	117.0	2E5UB@1|root,330IM@2|Bacteria,1VFEC@1239|Firmicutes,24UNV@186801|Clostridia,27Q7G@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02572	608534.GCWU000341_00935	6.72e-86	257.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
PNCOCPKN_02574	411473.RUMCAL_01407	0.0	1025.0	COG1196@1|root,COG1196@2|Bacteria,1TPU3@1239|Firmicutes,248HY@186801|Clostridia,3WGDP@541000|Ruminococcaceae	186801|Clostridia	D	MobA MobL family protein	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
PNCOCPKN_02575	221027.JO40_02935	5.88e-59	189.0	2F07Q@1|root,33TB6@2|Bacteria,2J6EH@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02576	411471.SUBVAR_06054	2.01e-58	181.0	2B26K@1|root,31UPX@2|Bacteria,1V93Z@1239|Firmicutes,24JA0@186801|Clostridia,3WJCW@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3847
PNCOCPKN_02577	1235798.C817_01260	2.97e-76	227.0	COG1349@1|root,COG1349@2|Bacteria,1V4EI@1239|Firmicutes,24HRM@186801|Clostridia,27WVB@189330|Dorea	186801|Clostridia	K	DeoR-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_DeoR
PNCOCPKN_02578	411483.FAEPRAA2165_00850	1.79e-38	128.0	2CBNR@1|root,32T16@2|Bacteria,1VA97@1239|Firmicutes,24NAW@186801|Clostridia,3WJUG@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02579	1232443.BAIA02000032_gene1938	1.96e-184	513.0	COG1396@1|root,COG1396@2|Bacteria,1TT2N@1239|Firmicutes,2488F@186801|Clostridia,268RW@186813|unclassified Clostridiales	186801|Clostridia	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
PNCOCPKN_02580	397291.C804_01673	2.61e-44	150.0	29U77@1|root,30FH3@2|Bacteria,1UE1M@1239|Firmicutes,25IVP@186801|Clostridia,27SU2@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02581	397290.C810_00998	2.06e-49	159.0	2BBXH@1|root,325G0@2|Bacteria,1URHR@1239|Firmicutes,259DR@186801|Clostridia,27PYE@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02582	411467.BACCAP_03284	2.62e-87	256.0	2C5R4@1|root,2ZBQ6@2|Bacteria,1V1T6@1239|Firmicutes,24GMD@186801|Clostridia,269FK@186813|unclassified Clostridiales	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
PNCOCPKN_02583	1378168.N510_03122	3.93e-59	182.0	COG3655@1|root,COG3655@2|Bacteria,1V27G@1239|Firmicutes	1239|Firmicutes	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
PNCOCPKN_02584	658086.HMPREF0994_05525	0.0	1070.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,27J4S@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Domain of unknown function (DUF4368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
PNCOCPKN_02585	742765.HMPREF9457_03599	2.62e-69	211.0	2EKB3@1|root,33E1G@2|Bacteria,1VN6B@1239|Firmicutes,24UHU@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF5300)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5301
PNCOCPKN_02586	428125.CLOLEP_03476	1.06e-30	108.0	2CM6M@1|root,32SDU@2|Bacteria,1VCHU@1239|Firmicutes,24NMC@186801|Clostridia,3WK8X@541000|Ruminococcaceae	186801|Clostridia	S	Transposon-encoded protein TnpW	-	-	-	-	-	-	-	-	-	-	-	-	TnpW
PNCOCPKN_02587	428125.CLOLEP_03477	2.85e-208	575.0	COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,248F0@186801|Clostridia,3WG7N@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
PNCOCPKN_02588	428125.CLOLEP_03478	1.25e-168	474.0	COG3935@1|root,COG3935@2|Bacteria,1TQ65@1239|Firmicutes,249Q8@186801|Clostridia,3WHMR@541000|Ruminococcaceae	186801|Clostridia	L	Phage replisome organizer N-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_rep_org_N
PNCOCPKN_02589	428125.CLOLEP_03479	0.0	1070.0	COG1196@1|root,COG1196@2|Bacteria,1UHVD@1239|Firmicutes,25E44@186801|Clostridia,3WSQ1@541000|Ruminococcaceae	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
PNCOCPKN_02590	428125.CLOLEP_03480	1.18e-86	255.0	2C2YH@1|root,2ZBKZ@2|Bacteria,1V3N8@1239|Firmicutes,24FYJ@186801|Clostridia,3WIW7@541000|Ruminococcaceae	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
PNCOCPKN_02591	658086.HMPREF0994_05773	2.85e-109	316.0	2F6MD@1|root,33Z41@2|Bacteria,1VWMW@1239|Firmicutes,252CF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02592	658086.HMPREF0994_05774	7.46e-149	419.0	28T24@1|root,2ZFBB@2|Bacteria,1W48U@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02593	1235793.C809_02249	3.96e-24	90.9	2CDEH@1|root,32RXK@2|Bacteria,1VA17@1239|Firmicutes,24MPR@186801|Clostridia,27PKS@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Maff2 family	-	-	-	-	-	-	-	-	-	-	-	-	Maff2
PNCOCPKN_02594	742741.HMPREF9475_02321	4.96e-151	441.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia,21XRZ@1506553|Lachnoclostridium	186801|Clostridia	U	COG COG3505 Type IV secretory pathway, VirD4 components	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf,TraG-D_C
PNCOCPKN_02595	1297617.JPJD01000080_gene1397	2.57e-27	99.4	2E8ED@1|root,332SU@2|Bacteria,1VJ6A@1239|Firmicutes,24SJK@186801|Clostridia,26BRY@186813|unclassified Clostridiales	186801|Clostridia	S	Transposon-encoded protein TnpW	-	-	-	-	-	-	-	-	-	-	-	-	TnpW
PNCOCPKN_02596	658086.HMPREF0994_06814	0.0	1228.0	COG0358@1|root,COG3598@1|root,COG0358@2|Bacteria,COG3598@2|Bacteria,1TQKP@1239|Firmicutes,247WJ@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,DUF3991,Toprim_2
PNCOCPKN_02597	1203606.HMPREF1526_01062	5.9e-109	327.0	COG1196@1|root,COG1196@2|Bacteria,1TPU3@1239|Firmicutes,248HY@186801|Clostridia,36DJZ@31979|Clostridiaceae	186801|Clostridia	D	MobA MobL family protein	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
PNCOCPKN_02598	411462.DORLON_00197	1.27e-195	552.0	COG1196@1|root,COG1196@2|Bacteria,1TPU3@1239|Firmicutes,248HY@186801|Clostridia,27WFG@189330|Dorea	186801|Clostridia	D	COG COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
PNCOCPKN_02599	1226325.HMPREF1548_03078	4.05e-55	174.0	292P2@1|root,2ZQ6W@2|Bacteria,1V4YF@1239|Firmicutes,24I6C@186801|Clostridia,36RZF@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF3847)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3847
PNCOCPKN_02600	545696.HOLDEFILI_03306	5.57e-21	83.6	2FE0M@1|root,3460U@2|Bacteria,1W0A0@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02602	397288.C806_04570	2.21e-05	53.5	COG1345@1|root,COG1345@2|Bacteria,1VU42@1239|Firmicutes,24Y6R@186801|Clostridia,27KHZ@186928|unclassified Lachnospiraceae	186801|Clostridia	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	-	-	-	-	-	-	-	-	-	FliD_C
PNCOCPKN_02603	585394.RHOM_06765	2.9e-58	182.0	COG1725@1|root,COG1725@2|Bacteria,1VA2B@1239|Firmicutes,24N57@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, GntR family	-	-	-	-	-	-	-	-	-	-	-	-	GntR
PNCOCPKN_02604	585394.RHOM_06760	7.49e-130	372.0	COG1131@1|root,COG1131@2|Bacteria,1TPUP@1239|Firmicutes,249FR@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PNCOCPKN_02605	585394.RHOM_06755	1.56e-61	202.0	COG1131@1|root,COG1131@2|Bacteria,1VF25@1239|Firmicutes,248Y7@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02606	622312.ROSEINA2194_00367	0.0	942.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	E1-E2_ATPase,Hydrolase
PNCOCPKN_02607	585394.RHOM_06750	7.2e-314	857.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia	186801|Clostridia	C	'glutamate synthase	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
PNCOCPKN_02608	622312.ROSEINA2194_00370	9.43e-202	559.0	COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,247YB@186801|Clostridia	186801|Clostridia	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	pyrK_1	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146,R10159	RC00065	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
PNCOCPKN_02609	585394.RHOM_06740	5.41e-162	457.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia	186801|Clostridia	S	Abc transporter	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
PNCOCPKN_02610	585394.RHOM_06735	2.53e-179	505.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia	186801|Clostridia	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
PNCOCPKN_02611	622312.ROSEINA2194_00374	2.77e-160	461.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia	186801|Clostridia	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PNCOCPKN_02612	622312.ROSEINA2194_04232	4.7e-131	379.0	COG2703@1|root,COG2703@2|Bacteria,1VBEC@1239|Firmicutes,24NV2@186801|Clostridia	186801|Clostridia	P	Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
PNCOCPKN_02613	585394.RHOM_06720	4.9e-196	546.0	COG0523@1|root,COG3689@1|root,COG0523@2|Bacteria,COG3689@2|Bacteria,1TS8P@1239|Firmicutes,248DY@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	cobW
PNCOCPKN_02614	622312.ROSEINA2194_03581	1.65e-190	539.0	COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia	186801|Clostridia	K	CobW P47K family protein	cobW	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
PNCOCPKN_02615	622312.ROSEINA2194_03578	0.0	940.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PNCOCPKN_02616	585394.RHOM_06020	0.0	917.0	COG1070@1|root,COG1070@2|Bacteria,1TP91@1239|Firmicutes,24A4Z@186801|Clostridia	186801|Clostridia	G	Carbohydrate kinase, FGGY family protein	araB	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
PNCOCPKN_02617	585394.RHOM_06025	0.0	967.0	COG2160@1|root,COG2160@2|Bacteria,1TPXC@1239|Firmicutes,24A08@186801|Clostridia	186801|Clostridia	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
PNCOCPKN_02618	585394.RHOM_06035	8.34e-147	414.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia	186801|Clostridia	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
PNCOCPKN_02619	585394.RHOM_06040	1.04e-166	469.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia	186801|Clostridia	G	Transketolase, thiamine diphosphate binding domain	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
PNCOCPKN_02620	585394.RHOM_06045	1.49e-188	528.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia	186801|Clostridia	G	Transketolase	tktB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
PNCOCPKN_02621	585394.RHOM_06050	1.63e-169	473.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia	186801|Clostridia	G	L-ribulose-5-phosphate 4-epimerase	ulaF	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
PNCOCPKN_02622	585394.RHOM_06055	1.45e-175	498.0	COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,249DZ@186801|Clostridia	186801|Clostridia	G	Converts alpha-aldose to the beta-anomer	mro	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
PNCOCPKN_02623	622312.ROSEINA2194_04168	1.07e-203	577.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
PNCOCPKN_02624	1121115.AXVN01000100_gene825	2.79e-82	258.0	COG4467@1|root,COG4467@2|Bacteria,1UYI4@1239|Firmicutes,2497B@186801|Clostridia	186801|Clostridia	S	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
PNCOCPKN_02625	457412.RSAG_00453	1.88e-24	97.8	COG4467@1|root,COG4467@2|Bacteria,1UYI4@1239|Firmicutes,2497B@186801|Clostridia	186801|Clostridia	S	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
PNCOCPKN_02626	500632.CLONEX_00591	1.7e-282	851.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,1TPQA@1239|Firmicutes,2491X@186801|Clostridia	186801|Clostridia	L	helicase C-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,N6_Mtase,ResIII,SNF2_N
PNCOCPKN_02627	861454.HMPREF9099_01778	5.63e-38	134.0	2AHN9@1|root,31806@2|Bacteria,1V94S@1239|Firmicutes,24MK7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02629	1235802.C823_01624	1.5e-116	344.0	28MNT@1|root,2ZAY9@2|Bacteria,1UJWE@1239|Firmicutes,248QQ@186801|Clostridia,25Y0Q@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02630	665950.HMPREF1025_02671	1.74e-94	286.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,24EUS@186801|Clostridia,27KUD@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
PNCOCPKN_02631	665950.HMPREF1025_02672	9.11e-92	268.0	2BCV8@1|root,326FY@2|Bacteria,1USD3@1239|Firmicutes,25ACC@186801|Clostridia,27Q62@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
PNCOCPKN_02632	665950.HMPREF1025_02673	0.0	886.0	COG0860@1|root,COG0860@2|Bacteria,1TWQM@1239|Firmicutes,24DKD@186801|Clostridia,27K9I@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_2,Amidase_3,Big_5,CW_binding_2,Cu_amine_oxidN1,Glucosaminidase
PNCOCPKN_02633	665950.HMPREF1025_02730	1.82e-62	192.0	2E6I4@1|root,3315A@2|Bacteria,1VBDX@1239|Firmicutes,25HM7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02634	665950.HMPREF1025_02731	4.08e-78	232.0	2CGYE@1|root,32T72@2|Bacteria,1VBA8@1239|Firmicutes,24K9V@186801|Clostridia,27PX4@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02635	665950.HMPREF1025_02732	1.6e-33	117.0	COG2378@1|root,COG2378@2|Bacteria,1V7YK@1239|Firmicutes,24K0I@186801|Clostridia,27NTC@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn_helix, Deoxyribose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_DeoR
PNCOCPKN_02636	1235802.C823_01857	9.89e-76	226.0	COG1396@1|root,COG1396@2|Bacteria,1VAS5@1239|Firmicutes,25FAR@186801|Clostridia,25Z50@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PNCOCPKN_02637	1235800.C819_00707	7.16e-82	243.0	COG3682@1|root,COG3682@2|Bacteria,1V7EY@1239|Firmicutes,24N11@186801|Clostridia,27M67@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Penicillinase repressor	blaI	-	-	ko:K02171	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01504,ko03000	-	-	-	Penicillinase_R
PNCOCPKN_02638	1235802.C823_01855	0.0	1117.0	COG2602@1|root,COG4219@1|root,COG2602@2|Bacteria,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,249NV@186801|Clostridia,25VWV@186806|Eubacteriaceae	186801|Clostridia	KT	BlaR1 peptidase M56	blaR	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	Peptidase_M56,Transpeptidase
PNCOCPKN_02640	1235800.C819_00709	1.04e-46	161.0	2DV46@1|root,33TYU@2|Bacteria,1UWES@1239|Firmicutes,259P3@186801|Clostridia,27M27@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02641	585394.RHOM_15315	2.14e-78	235.0	28Q48@1|root,2ZCMI@2|Bacteria,1V39F@1239|Firmicutes,24GC4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02643	1235800.C819_00711	2.45e-287	786.0	28IBJ@1|root,2Z8XY@2|Bacteria,1UCWW@1239|Firmicutes,24DUG@186801|Clostridia,27K2E@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02644	1235802.C823_01851	6.49e-305	831.0	28IBJ@1|root,2Z938@2|Bacteria,1TT2I@1239|Firmicutes,249F0@186801|Clostridia,25YE4@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02645	665950.HMPREF1025_02742	1.5e-277	761.0	28IBJ@1|root,2Z8E0@2|Bacteria,1UYB9@1239|Firmicutes,24BIZ@186801|Clostridia,27IBT@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02646	665950.HMPREF1025_02743	0.0	1266.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,248PI@186801|Clostridia,27KSE@186928|unclassified Lachnospiraceae	186801|Clostridia	M	NTF2-like N-terminal transpeptidase domain	pbpC	-	3.4.16.4	ko:K05515,ko:K21467	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	MecA_N,PBP_dimer,Transpeptidase
PNCOCPKN_02647	657322.FPR_23970	0.0	1080.0	COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,25B03@186801|Clostridia,3WGW2@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
PNCOCPKN_02648	1235798.C817_03705	1.59e-215	597.0	COG3943@1|root,COG3943@2|Bacteria,1TPH4@1239|Firmicutes,248NI@186801|Clostridia,27W4A@189330|Dorea	186801|Clostridia	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_RhuM
PNCOCPKN_02649	1111134.HMPREF1253_0596	3.43e-08	51.2	2E3S9@1|root,32YPV@2|Bacteria,1VEQV@1239|Firmicutes,24SJU@186801|Clostridia,22HTS@1570339|Peptoniphilaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02650	657322.FPR_24000	1.37e-289	792.0	COG1196@1|root,COG1196@2|Bacteria,1UQCD@1239|Firmicutes,24AY9@186801|Clostridia,3WSPG@541000|Ruminococcaceae	186801|Clostridia	D	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
PNCOCPKN_02651	657322.FPR_24010	0.0	921.0	COG3378@1|root,COG3378@2|Bacteria,1TSGZ@1239|Firmicutes,24CI8@186801|Clostridia,3WHNR@541000|Ruminococcaceae	186801|Clostridia	S	Phage plasmid primase, P4 family	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	D5_N,Pox_D5
PNCOCPKN_02652	657322.FPR_24020	2e-148	417.0	COG0358@1|root,COG0358@2|Bacteria,1V0WR@1239|Firmicutes,24C9Q@186801|Clostridia,3WI6F@541000|Ruminococcaceae	186801|Clostridia	L	CHC2 zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHC2
PNCOCPKN_02653	657322.FPR_24030	3.24e-44	143.0	COG2909@1|root,COG2909@2|Bacteria,1VEQQ@1239|Firmicutes,24RGN@186801|Clostridia,3WRQZ@541000|Ruminococcaceae	186801|Clostridia	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02654	657322.FPR_24040	9.15e-170	476.0	COG3093@1|root,COG3093@2|Bacteria,1UXZS@1239|Firmicutes,24BNR@186801|Clostridia,3WPUF@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PNCOCPKN_02655	657322.FPR_24050	3.98e-98	288.0	COG0568@1|root,COG0568@2|Bacteria	2|Bacteria	K	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086,ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
PNCOCPKN_02656	657322.FPR_24070	4.16e-159	446.0	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,249TG@186801|Clostridia,3WIB0@541000|Ruminococcaceae	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PNCOCPKN_02657	657322.FPR_24080	1.76e-233	643.0	COG0642@1|root,COG2205@2|Bacteria,1TSIC@1239|Firmicutes,248W8@186801|Clostridia,3WGTN@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
PNCOCPKN_02658	657322.FPR_24090	3.67e-178	496.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,3WG7Z@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PNCOCPKN_02659	657322.FPR_24100	0.0	1409.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia,3WGQ2@541000|Ruminococcaceae	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
PNCOCPKN_02660	657322.FPR_24110	2.61e-53	167.0	2CZEX@1|root,32T68@2|Bacteria,1VB18@1239|Firmicutes,24MZP@186801|Clostridia,3WPUQ@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02661	1235798.C817_01018	1.63e-261	733.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,27V9N@189330|Dorea	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
PNCOCPKN_02663	585394.RHOM_10905	0.0	1198.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia	186801|Clostridia	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
PNCOCPKN_02664	585394.RHOM_10910	1.69e-89	268.0	COG0789@1|root,COG0789@2|Bacteria,1V1M9@1239|Firmicutes,24FUE@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1836
PNCOCPKN_02665	585394.RHOM_10915	1.08e-60	187.0	COG4496@1|root,COG4496@2|Bacteria,1VA04@1239|Firmicutes,24MX9@186801|Clostridia	186801|Clostridia	S	protein, YerC YecD	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
PNCOCPKN_02666	585394.RHOM_10920	1.54e-96	293.0	COG1266@1|root,COG1266@2|Bacteria,1VF60@1239|Firmicutes,24QSC@186801|Clostridia	186801|Clostridia	S	CAAX amino terminal protease family protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
PNCOCPKN_02667	622312.ROSEINA2194_02313	6.58e-217	603.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
PNCOCPKN_02668	585394.RHOM_10930	3.4e-248	686.0	COG0436@1|root,COG0436@2|Bacteria,1TP36@1239|Firmicutes,248ZV@186801|Clostridia	186801|Clostridia	E	Aminotransferase	yhdR	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
PNCOCPKN_02669	622312.ROSEINA2194_02311	0.0	940.0	COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,247ZN@186801|Clostridia	186801|Clostridia	G	UDPglucose--hexose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
PNCOCPKN_02670	622312.ROSEINA2194_02310	6.61e-265	729.0	COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,247U8@186801|Clostridia	186801|Clostridia	G	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
PNCOCPKN_02671	585394.RHOM_10945	1.64e-252	695.0	COG3867@1|root,COG3867@2|Bacteria,1TQDZ@1239|Firmicutes,24CPM@186801|Clostridia	186801|Clostridia	G	arabinogalactan	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_53
PNCOCPKN_02672	622312.ROSEINA2194_04219	0.0	1736.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia	186801|Clostridia	G	beta-galactosidase	lacZ	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
PNCOCPKN_02673	622312.ROSEINA2194_04218	2.83e-204	567.0	COG2207@1|root,COG2207@2|Bacteria,1V0IW@1239|Firmicutes,24BME@186801|Clostridia	186801|Clostridia	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
PNCOCPKN_02674	622312.ROSEINA2194_04217	6.33e-50	157.0	2EAM1@1|root,334PP@2|Bacteria,1VI13@1239|Firmicutes,24ST8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02675	622312.ROSEINA2194_04216	0.0	1263.0	2DBG1@1|root,2Z91R@2|Bacteria,1TQV4@1239|Firmicutes,24CK0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02676	622312.ROSEINA2194_04215	5.96e-181	506.0	COG3833@1|root,COG3833@2|Bacteria,1TRB7@1239|Firmicutes,248A7@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
PNCOCPKN_02677	622312.ROSEINA2194_04214	0.0	879.0	COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,247MA@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
PNCOCPKN_02678	622312.ROSEINA2194_04213	7.29e-252	699.0	COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia	186801|Clostridia	G	ABC transporter, solute-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
PNCOCPKN_02679	585394.RHOM_10990	1.67e-180	509.0	COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,248WQ@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
PNCOCPKN_02680	1163671.JAGI01000002_gene2603	1.21e-246	692.0	COG3507@1|root,COG3507@2|Bacteria,1TP5K@1239|Firmicutes,247R2@186801|Clostridia,36ES1@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.37,3.2.1.55	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	-	R01433,R01762	RC00467	ko00000,ko00001,ko01000	-	GH43,GH51	-	Glyco_hydro_43
PNCOCPKN_02681	585394.RHOM_05745	5.07e-251	707.0	COG2755@1|root,COG2755@2|Bacteria,1TPYH@1239|Firmicutes,2486S@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Lipase_GDSL_2
PNCOCPKN_02682	1280390.CBQR020000071_gene1456	0.0	907.0	2DB7A@1|root,2Z7KK@2|Bacteria,1TQ2C@1239|Firmicutes,4HFKE@91061|Bacilli,26S01@186822|Paenibacillaceae	91061|Bacilli	S	Glycosyl hydrolase family 115	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_115
PNCOCPKN_02683	1226325.HMPREF1548_05296	4.8e-199	561.0	COG3405@1|root,COG3405@2|Bacteria,1U1E1@1239|Firmicutes,24878@186801|Clostridia,36FZI@31979|Clostridiaceae	186801|Clostridia	G	family 8	-	-	3.2.1.156	ko:K15531	-	-	-	-	ko00000,ko01000	-	GH8	-	Dockerin_1,Glyco_hydro_8,Polysacc_deac_1
PNCOCPKN_02684	397291.C804_04827	9.53e-177	497.0	COG0395@1|root,COG0395@2|Bacteria,1TP14@1239|Firmicutes,2481Z@186801|Clostridia,27KBY@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17320	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
PNCOCPKN_02685	397291.C804_04826	3.21e-193	540.0	COG4209@1|root,COG4209@2|Bacteria,1TQ64@1239|Firmicutes,24YP3@186801|Clostridia,27KGJ@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
PNCOCPKN_02686	397291.C804_04825	0.0	991.0	COG1653@1|root,COG1653@2|Bacteria,1TQWF@1239|Firmicutes,24CWD@186801|Clostridia,27IIE@186928|unclassified Lachnospiraceae	186801|Clostridia	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
PNCOCPKN_02687	585394.RHOM_05765	9.13e-177	515.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1UYK2@1239|Firmicutes,247MJ@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
PNCOCPKN_02688	1469948.JPNB01000002_gene2919	8.23e-154	461.0	COG2972@1|root,COG2972@2|Bacteria,1TPUF@1239|Firmicutes,2491H@186801|Clostridia,36DCG@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase
PNCOCPKN_02689	397291.C804_04887	0.0	1083.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,27J28@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
PNCOCPKN_02690	585394.RHOM_10995	0.0	1001.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia	186801|Clostridia	G	beta-galactosidase	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
PNCOCPKN_02691	641112.ACOK01000097_gene867	1.84e-79	253.0	COG5464@1|root,COG5464@2|Bacteria,1V3CA@1239|Firmicutes,24H4R@186801|Clostridia,3WK37@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
PNCOCPKN_02692	478749.BRYFOR_07844	2.99e-73	238.0	COG5464@1|root,COG5464@2|Bacteria,1V3CA@1239|Firmicutes,24H4R@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
PNCOCPKN_02694	411902.CLOBOL_06104	2.1e-113	333.0	COG0483@1|root,COG0483@2|Bacteria,1TR4E@1239|Firmicutes,24KJZ@186801|Clostridia,22041@1506553|Lachnoclostridium	186801|Clostridia	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
PNCOCPKN_02695	585394.RHOM_03730	1.38e-115	337.0	COG4912@1|root,COG4912@2|Bacteria,1TQII@1239|Firmicutes,248N8@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
PNCOCPKN_02696	585394.RHOM_03725	2.51e-129	372.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia	186801|Clostridia	V	ABC transporter	lolD	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PNCOCPKN_02698	585394.RHOM_03715	5.77e-221	624.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,24AWU@186801|Clostridia	186801|Clostridia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PNCOCPKN_02699	585394.RHOM_03710	6.79e-136	407.0	COG0845@1|root,COG0845@2|Bacteria,1V96V@1239|Firmicutes,24BEV@186801|Clostridia	186801|Clostridia	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
PNCOCPKN_02700	585394.RHOM_03705	5.46e-86	283.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
PNCOCPKN_02701	1280698.AUJS01000100_gene153	6.16e-127	363.0	COG2039@1|root,COG2039@2|Bacteria,1TRRX@1239|Firmicutes,248T4@186801|Clostridia,27W6C@189330|Dorea	186801|Clostridia	O	Pyroglutamyl peptidase	pcp	-	3.4.19.3	ko:K01304	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C15
PNCOCPKN_02702	622312.ROSEINA2194_01879	3.88e-73	222.0	2E3N2@1|root,32YK7@2|Bacteria,1VEYM@1239|Firmicutes,24QJ0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02703	585394.RHOM_03700	3.56e-142	406.0	COG0561@1|root,COG0561@2|Bacteria,1V1JB@1239|Firmicutes,24AY8@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
PNCOCPKN_02704	585394.RHOM_10215	0.0	972.0	COG0369@1|root,COG1151@2|Bacteria,1TP8X@1239|Firmicutes,247IN@186801|Clostridia	186801|Clostridia	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
PNCOCPKN_02706	622312.ROSEINA2194_03062	2.72e-224	621.0	COG0371@1|root,COG0371@2|Bacteria,1TR6W@1239|Firmicutes,25CDJ@186801|Clostridia	186801|Clostridia	C	3-dehydroquinate synthase	egsA	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
PNCOCPKN_02708	59374.Fisuc_1259	1.79e-10	65.5	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,Response_reg
PNCOCPKN_02710	585394.RHOM_03675	1.56e-84	253.0	2ANER@1|root,31DDD@2|Bacteria,1V46U@1239|Firmicutes,24JDI@186801|Clostridia	186801|Clostridia	S	stage V sporulation protein AC	spoVAC	-	-	ko:K06405	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
PNCOCPKN_02711	585394.RHOM_03670	1.36e-46	152.0	2EJW5@1|root,33DKW@2|Bacteria,1VPSK@1239|Firmicutes,24W6H@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF3837)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3837
PNCOCPKN_02712	585394.RHOM_03665	4.05e-55	176.0	2AF43@1|root,3152T@2|Bacteria,1VFMI@1239|Firmicutes,24RBI@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K06404	-	-	-	-	ko00000	-	-	-	SpoVAB
PNCOCPKN_02713	585394.RHOM_03660	9.28e-112	325.0	28PNE@1|root,2ZCB6@2|Bacteria,1V214@1239|Firmicutes,24DN2@186801|Clostridia	186801|Clostridia	S	COG NOG11305 non supervised orthologous group	spoVAA	-	-	ko:K06403	-	-	-	-	ko00000	-	-	-	SporV_AA
PNCOCPKN_02715	622312.ROSEINA2194_02462	1.73e-134	386.0	COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,24A25@186801|Clostridia	186801|Clostridia	K	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7,ThrE
PNCOCPKN_02716	585394.RHOM_03645	1.84e-72	221.0	COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,24R80@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ThrE_2
PNCOCPKN_02717	1410618.JNKI01000001_gene1495	5.84e-33	135.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1U4YK@1239|Firmicutes,4H6FE@909932|Negativicutes	909932|Negativicutes	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
PNCOCPKN_02719	666681.M301_0409	3.2e-21	106.0	COG3850@1|root,COG5001@1|root,COG3850@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VKCJ@28216|Betaproteobacteria,2KKKT@206350|Nitrosomonadales	206350|Nitrosomonadales	T	Periplasmic sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,EAL,GGDEF,HAMP
PNCOCPKN_02720	585394.RHOM_03640	6.56e-289	809.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247Q9@186801|Clostridia	186801|Clostridia	S	Abc transporter	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
PNCOCPKN_02721	622312.ROSEINA2194_00341	0.0	943.0	COG4868@1|root,COG4868@2|Bacteria,1TQYE@1239|Firmicutes,247YI@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1846
PNCOCPKN_02722	411489.CLOL250_02693	6.48e-111	349.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	AMPK1_CBM,Alpha-amylase,Big_2,Big_5,CBM_48,Flg_new,Gram_pos_anchor,PUD,SLH
PNCOCPKN_02723	1121344.JHZO01000003_gene939	5.5e-59	189.0	COG1704@1|root,COG1704@2|Bacteria,1V3Z0@1239|Firmicutes,24IH4@186801|Clostridia,3WM16@541000|Ruminococcaceae	186801|Clostridia	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
PNCOCPKN_02725	1291050.JAGE01000001_gene844	6.25e-61	202.0	COG3290@1|root,COG3290@2|Bacteria,1TS6E@1239|Firmicutes,24DDI@186801|Clostridia,3WS78@541000|Ruminococcaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
PNCOCPKN_02727	622312.ROSEINA2194_00344	1.65e-130	375.0	COG3279@1|root,COG3279@2|Bacteria,1TSDB@1239|Firmicutes,24MQ4@186801|Clostridia	186801|Clostridia	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
PNCOCPKN_02728	585394.RHOM_03635	1.16e-235	674.0	COG2200@1|root,COG2200@2|Bacteria,1TQRN@1239|Firmicutes,247QG@186801|Clostridia	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
PNCOCPKN_02729	622312.ROSEINA2194_02467	9.5e-142	402.0	COG2357@1|root,COG2357@2|Bacteria,1TSC9@1239|Firmicutes,25CET@186801|Clostridia	186801|Clostridia	S	RelA SpoT domain protein	spoT	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
PNCOCPKN_02730	537007.BLAHAN_06528	7.23e-192	539.0	COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,247P0@186801|Clostridia,3XZ5V@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K07035	-	-	-	-	ko00000	-	-	-	PTS_EIIC_2
PNCOCPKN_02731	1064535.MELS_0830	4.14e-25	106.0	292FV@1|root,2ZQ01@2|Bacteria,1V62Q@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02732	1297581.H919_06536	1.3e-127	381.0	COG1106@1|root,COG1106@2|Bacteria,1TSBY@1239|Firmicutes,4HIIN@91061|Bacilli	91061|Bacilli	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K06926	-	-	-	-	ko00000	-	-	-	AAA_21
PNCOCPKN_02733	1235798.C817_00762	9.75e-166	481.0	28K2E@1|root,2Z9RR@2|Bacteria,1TRJ6@1239|Firmicutes,24F8S@186801|Clostridia	186801|Clostridia	S	CRISPR-associated protein (Cas_Csm6)	-	-	-	-	-	-	-	-	-	-	-	-	Cas_Csm6
PNCOCPKN_02734	1235798.C817_00761	4.37e-45	148.0	COG1343@1|root,COG1343@2|Bacteria,1VFRC@1239|Firmicutes,24R2N@186801|Clostridia	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
PNCOCPKN_02735	1235798.C817_00760	2.1e-187	526.0	COG1518@1|root,COG1518@2|Bacteria,1TQWG@1239|Firmicutes,24889@186801|Clostridia	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
PNCOCPKN_02736	1235798.C817_00759	1.61e-142	416.0	COG1332@1|root,COG1332@2|Bacteria,1V8JA@1239|Firmicutes,24IAY@186801|Clostridia	186801|Clostridia	L	CRISPR-associated RAMP protein, Csm5 family	csm5	-	-	ko:K19140	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
PNCOCPKN_02737	1235798.C817_00758	7.24e-119	350.0	COG1567@1|root,COG1567@2|Bacteria,1V4UZ@1239|Firmicutes,24IT6@186801|Clostridia	186801|Clostridia	L	CRISPR-associated RAMP protein, Csm4 family	csm4	-	-	ko:K19139	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
PNCOCPKN_02738	1235798.C817_00757	2.67e-98	291.0	COG1337@1|root,COG1337@2|Bacteria,1V3DM@1239|Firmicutes,24IQD@186801|Clostridia	186801|Clostridia	L	CRISPR-associated RAMP protein, Csm3 family	csm3	-	-	ko:K09002	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
PNCOCPKN_02739	1235798.C817_00756	4.57e-47	155.0	COG1421@1|root,COG1421@2|Bacteria,1VGBY@1239|Firmicutes,24R4K@186801|Clostridia	186801|Clostridia	L	CRISPR-associated protein, Csm2 family	csm2	-	-	ko:K19138	-	-	-	-	ko00000,ko02048	-	-	-	Csm2_III-A
PNCOCPKN_02740	1235798.C817_00755	0.0	925.0	COG1353@1|root,COG1353@2|Bacteria,1TRW5@1239|Firmicutes,24BI3@186801|Clostridia	186801|Clostridia	S	CRISPR-associated protein, Csm1 family	csm1	-	-	ko:K07016	-	-	-	-	ko00000,ko02048	-	-	-	HD
PNCOCPKN_02741	1235798.C817_00754	4.78e-100	298.0	COG5551@1|root,COG5551@2|Bacteria,1V7VJ@1239|Firmicutes,24IY3@186801|Clostridia	186801|Clostridia	S	CRISPR-associated endoribonuclease Cas6	cas6	-	-	-	-	-	-	-	-	-	-	-	CRISPR_Cas6
PNCOCPKN_02742	633697.EubceDRAFT1_0116	5.32e-117	337.0	COG2184@1|root,COG2184@2|Bacteria,1TPUZ@1239|Firmicutes,248XF@186801|Clostridia,25W8Z@186806|Eubacteriaceae	186801|Clostridia	D	Fic/DOC family	fic	-	-	ko:K04095	-	-	-	-	ko00000,ko03036	-	-	-	Bro-N,Fic
PNCOCPKN_02743	622312.ROSEINA2194_02469	2.72e-51	162.0	2CGVU@1|root,32S4Q@2|Bacteria,1V9YX@1239|Firmicutes,24NX8@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02744	622312.ROSEINA2194_02470	2.89e-131	380.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
PNCOCPKN_02745	585394.RHOM_03615	2.02e-221	612.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia	186801|Clostridia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
PNCOCPKN_02746	585394.RHOM_03610	0.0	1992.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia	186801|Clostridia	L	DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
PNCOCPKN_02747	397291.C804_03982	0.0	1011.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,27K0D@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3372,PUD
PNCOCPKN_02748	1280676.AUJO01000012_gene3474	0.0	931.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,4BYXB@830|Butyrivibrio	186801|Clostridia	G	Alpha-amylase domain	malL	-	3.2.1.1,3.2.1.10	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
PNCOCPKN_02749	537007.BLAHAN_05096	8.9e-313	882.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,3XZ46@572511|Blautia	186801|Clostridia	G	Domain of unknown function (DUF5110)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4968,DUF5110,Glyco_hydro_31
PNCOCPKN_02750	556261.HMPREF0240_04156	4e-35	130.0	COG5578@1|root,COG5578@2|Bacteria,1V3XD@1239|Firmicutes,24K78@186801|Clostridia,36KAQ@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
PNCOCPKN_02751	610130.Closa_0870	1.41e-259	753.0	COG0637@1|root,COG1554@1|root,COG0637@2|Bacteria,COG1554@2|Bacteria,1TQMB@1239|Firmicutes,247J6@186801|Clostridia,223W0@1506553|Lachnoclostridium	186801|Clostridia	G	hydrolase family 65 central catalytic	-	-	2.4.1.230,2.4.1.8	ko:K00691,ko:K04844,ko:K10231	ko00500,ko01100,map00500,map01100	-	R01555	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2
PNCOCPKN_02752	180332.JTGN01000002_gene5510	1.54e-126	368.0	COG0395@1|root,COG0395@2|Bacteria,1TRXW@1239|Firmicutes,25C4N@186801|Clostridia	186801|Clostridia	P	ABC-type sugar transport system, permease component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
PNCOCPKN_02753	180332.JTGN01000002_gene5509	9.27e-141	406.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
PNCOCPKN_02754	610130.Closa_0867	1.86e-136	407.0	COG1653@1|root,COG1653@2|Bacteria,1TR0C@1239|Firmicutes,248RD@186801|Clostridia,221RJ@1506553|Lachnoclostridium	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8
PNCOCPKN_02755	1382315.JPOI01000001_gene107	1.11e-83	264.0	COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,4HBNT@91061|Bacilli,1WFIB@129337|Geobacillus	91061|Bacilli	K	helix_turn _helix lactose operon repressor	cytR	-	-	ko:K02529,ko:K03604	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
PNCOCPKN_02756	1280696.ATVY01000004_gene422	7.68e-99	292.0	COG0637@1|root,COG0637@2|Bacteria,1UZE0@1239|Firmicutes,24DWR@186801|Clostridia,4BY5V@830|Butyrivibrio	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	pgmB	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
PNCOCPKN_02757	585394.RHOM_03595	1.9e-168	474.0	COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,2485C@186801|Clostridia	186801|Clostridia	S	Phospholipase, patatin family	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
PNCOCPKN_02758	483218.BACPEC_01903	7.63e-266	734.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,2685U@186813|unclassified Clostridiales	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PNCOCPKN_02759	622312.ROSEINA2194_02475	0.0	1422.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
PNCOCPKN_02760	1458462.JNLK01000001_gene1937	1.55e-156	453.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248IH@186801|Clostridia,27K39@186928|unclassified Lachnospiraceae	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
PNCOCPKN_02761	1458462.JNLK01000001_gene1936	0.0	1074.0	COG2206@1|root,COG3275@1|root,COG3292@1|root,COG2206@2|Bacteria,COG3275@2|Bacteria,COG3292@2|Bacteria,1UZN2@1239|Firmicutes,25EWN@186801|Clostridia	186801|Clostridia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,GAF_2,HAMP,HD,HD_5,PAS_9,Reg_prop,Response_reg,Y_Y_Y,dCache_1
PNCOCPKN_02762	411461.DORFOR_02222	2.51e-96	287.0	COG3404@1|root,COG3404@2|Bacteria,1V14R@1239|Firmicutes,24D90@186801|Clostridia,27VNB@189330|Dorea	186801|Clostridia	E	Formiminotransferase-cyclodeaminase	fchA	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
PNCOCPKN_02763	411462.DORLON_02488	3.7e-154	438.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,27VGK@189330|Dorea	186801|Clostridia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
PNCOCPKN_02764	622312.ROSEINA2194_04370	9.79e-159	463.0	COG1373@1|root,COG1373@2|Bacteria,1TQ8Z@1239|Firmicutes,2499K@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
PNCOCPKN_02765	585394.RHOM_11425	0.0	1395.0	COG1482@1|root,COG2723@1|root,COG1482@2|Bacteria,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1,PMI_typeI
PNCOCPKN_02766	585394.RHOM_11430	4.4e-174	496.0	COG2755@1|root,COG2755@2|Bacteria,1TQG2@1239|Firmicutes,24A1G@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
PNCOCPKN_02767	585394.RHOM_11435	1.01e-181	513.0	COG2755@1|root,COG2755@2|Bacteria,1TS75@1239|Firmicutes,24DPZ@186801|Clostridia	186801|Clostridia	E	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
PNCOCPKN_02768	585394.RHOM_11440	3.63e-248	681.0	COG2152@1|root,COG2152@2|Bacteria,1TQE7@1239|Firmicutes,249D0@186801|Clostridia	186801|Clostridia	G	PFAM Glycosidase	-	-	2.4.1.319,2.4.1.320	ko:K18785	-	-	R10811,R10829	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
PNCOCPKN_02769	585394.RHOM_11445	1.19e-279	764.0	COG2152@1|root,COG2152@2|Bacteria,1TNYI@1239|Firmicutes,24A1K@186801|Clostridia	186801|Clostridia	G	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose	-	-	2.4.1.281	ko:K16212	-	-	R09943	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
PNCOCPKN_02770	585394.RHOM_11450	1.67e-247	685.0	COG2942@1|root,COG2942@2|Bacteria,1TQMG@1239|Firmicutes,24C1F@186801|Clostridia	186801|Clostridia	G	Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)	-	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
PNCOCPKN_02771	1410616.JHXE01000013_gene255	5.67e-162	459.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia,3NGCJ@46205|Pseudobutyrivibrio	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
PNCOCPKN_02772	1469948.JPNB01000002_gene3876	1.34e-177	502.0	COG1175@1|root,COG1175@2|Bacteria,1TQHI@1239|Firmicutes,247ZB@186801|Clostridia,36HT0@31979|Clostridiaceae	186801|Clostridia	G	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
PNCOCPKN_02773	1280673.AUJJ01000009_gene3083	4.58e-238	668.0	COG1653@1|root,COG1653@2|Bacteria,1TS0C@1239|Firmicutes,249WW@186801|Clostridia,4BZ2U@830|Butyrivibrio	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1
PNCOCPKN_02774	585394.RHOM_11475	3.94e-149	430.0	COG1609@1|root,COG1609@2|Bacteria,1TT55@1239|Firmicutes,24A7X@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529,ko:K03604	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
PNCOCPKN_02775	397291.C804_03204	0.0	1089.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia,27I65@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolase family 36 N-terminal domain	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
PNCOCPKN_02776	585394.RHOM_11485	0.0	1045.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia	186801|Clostridia	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain II	-	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
PNCOCPKN_02777	1196322.A370_01851	4.4e-159	453.0	COG2730@1|root,COG2730@2|Bacteria,1TT32@1239|Firmicutes,24DD1@186801|Clostridia,36EG6@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02778	573061.Clocel_3339	4.23e-97	295.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1TQ2W@1239|Firmicutes,25BJI@186801|Clostridia	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding
PNCOCPKN_02779	622312.ROSEINA2194_02877	3.74e-85	270.0	COG1266@1|root,COG1266@2|Bacteria,1VCV8@1239|Firmicutes,24F20@186801|Clostridia	186801|Clostridia	S	CAAX amino terminal protease family protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
PNCOCPKN_02780	585394.RHOM_11490	1.48e-158	460.0	COG2843@1|root,COG2843@2|Bacteria,1UCFI@1239|Firmicutes,25CHR@186801|Clostridia	186801|Clostridia	M	Capsule synthesis protein	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
PNCOCPKN_02782	585394.RHOM_03980	1.23e-49	169.0	COG4709@1|root,COG4709@2|Bacteria,1VETQ@1239|Firmicutes,24G3G@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
PNCOCPKN_02783	622312.ROSEINA2194_02883	1.14e-59	185.0	COG1695@1|root,COG1695@2|Bacteria,1VACN@1239|Firmicutes,24MRF@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, PadR family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
PNCOCPKN_02784	585394.RHOM_03965	0.0	952.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,247KN@186801|Clostridia	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
PNCOCPKN_02785	585394.RHOM_03960	3.12e-128	380.0	COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,24C10@186801|Clostridia	186801|Clostridia	S	Secreted protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1002
PNCOCPKN_02786	585394.RHOM_03955	2.59e-180	507.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia	186801|Clostridia	I	Hydrolase, alpha beta domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
PNCOCPKN_02788	622312.ROSEINA2194_03374	0.0	879.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia	186801|Clostridia	L	Single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
PNCOCPKN_02789	622312.ROSEINA2194_03375	1.69e-113	332.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248GJ@186801|Clostridia	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA1	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
PNCOCPKN_02790	585394.RHOM_03935	2.26e-248	689.0	COG3409@1|root,COG3409@2|Bacteria,1TS29@1239|Firmicutes,247SQ@186801|Clostridia	186801|Clostridia	M	Peptidoglycan binding domain protein	sleC	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,SpoIID
PNCOCPKN_02791	622312.ROSEINA2194_03378	0.0	991.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
PNCOCPKN_02792	622312.ROSEINA2194_00443	2.54e-55	182.0	2DSNT@1|root,33GUR@2|Bacteria,1VNR5@1239|Firmicutes,24WQ3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02793	622312.ROSEINA2194_01974	5.51e-171	487.0	COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10540	ko02010,ko02030,map02010,map02030	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	Peripla_BP_4
PNCOCPKN_02794	585394.RHOM_03910	6.02e-83	261.0	COG1879@1|root,COG1879@2|Bacteria,1UD4W@1239|Firmicutes,24AYQ@186801|Clostridia	186801|Clostridia	G	COG1879 ABC-type sugar transport system periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
PNCOCPKN_02795	622312.ROSEINA2194_01972	0.0	932.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
PNCOCPKN_02796	622312.ROSEINA2194_01971	1.22e-275	766.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
PNCOCPKN_02797	585394.RHOM_03895	2.7e-38	130.0	2FJ6E@1|root,34AWI@2|Bacteria,1W149@1239|Firmicutes,254EU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02798	585394.RHOM_03890	3.55e-213	591.0	COG4211@1|root,COG4211@2|Bacteria,1UI1K@1239|Firmicutes,25EAQ@186801|Clostridia	186801|Clostridia	G	Belongs to the binding-protein-dependent transport system permease family	mglC	-	-	ko:K10541	ko02010,map02010	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	BPD_transp_2
PNCOCPKN_02799	622312.ROSEINA2194_01968	0.0	909.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia	186801|Clostridia	G	import. Responsible for energy coupling to the transport system	mglA	-	3.6.3.17	ko:K10542	ko02010,map02010	M00214	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.3	-	-	ABC_tran
PNCOCPKN_02800	585394.RHOM_03880	2e-202	568.0	COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10540	ko02010,ko02030,map02010,map02030	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	Peripla_BP_4,TAT_signal
PNCOCPKN_02801	585394.RHOM_03875	1.56e-65	202.0	COG1433@1|root,COG1433@2|Bacteria,1V7KS@1239|Firmicutes,24MUB@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
PNCOCPKN_02802	585394.RHOM_04225	1.45e-297	813.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
PNCOCPKN_02803	585394.RHOM_04220	9.79e-119	342.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia	186801|Clostridia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04225	Formyl_trans_N
PNCOCPKN_02804	585394.RHOM_04215	8.21e-225	622.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia	186801|Clostridia	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
PNCOCPKN_02805	585394.RHOM_04210	1.71e-105	305.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia	186801|Clostridia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
PNCOCPKN_02806	585394.RHOM_04205	0.0	982.0	COG2309@1|root,COG2309@2|Bacteria,1TSPE@1239|Firmicutes,24A6S@186801|Clostridia	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
PNCOCPKN_02807	585394.RHOM_04200	3.65e-114	330.0	COG1896@1|root,COG1896@2|Bacteria,1V3MK@1239|Firmicutes,24IBW@186801|Clostridia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
PNCOCPKN_02808	622312.ROSEINA2194_02252	1.03e-38	132.0	2ETB0@1|root,33KUX@2|Bacteria,1VPRN@1239|Firmicutes,24WSP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02809	1235802.C823_04890	3.17e-59	196.0	COG5433@1|root,COG5433@2|Bacteria,1V0JK@1239|Firmicutes,249XC@186801|Clostridia	186801|Clostridia	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
PNCOCPKN_02810	1408323.JQKK01000005_gene154	3.83e-42	143.0	29PCB@1|root,30AAJ@2|Bacteria,1V4H2@1239|Firmicutes,24IF4@186801|Clostridia,27M51@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02811	622312.ROSEINA2194_02683	3.27e-292	805.0	COG2326@1|root,COG2326@2|Bacteria,1TQQR@1239|Firmicutes,249HE@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	pap	-	-	-	-	-	-	-	-	-	-	-	PPK2
PNCOCPKN_02812	1235800.C819_00237	9.73e-174	498.0	COG3434@1|root,COG3434@2|Bacteria,1TPWC@1239|Firmicutes,248M1@186801|Clostridia,27J37@186928|unclassified Lachnospiraceae	186801|Clostridia	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
PNCOCPKN_02813	1235790.C805_01475	1.76e-103	304.0	COG1394@1|root,COG1394@2|Bacteria,1TQ4P@1239|Firmicutes,24Z7J@186801|Clostridia,25WFD@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
PNCOCPKN_02814	1235790.C805_01474	2.4e-273	754.0	COG1156@1|root,COG1156@2|Bacteria,1VSU1@1239|Firmicutes,2496H@186801|Clostridia,25VDA@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	ntpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
PNCOCPKN_02815	397288.C806_01359	0.0	931.0	COG1155@1|root,COG1155@2|Bacteria,1TPGS@1239|Firmicutes,24882@186801|Clostridia,27IS3@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	ntpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
PNCOCPKN_02816	357809.Cphy_3443	1.99e-21	94.0	COG1390@1|root,COG1390@2|Bacteria,1V7UJ@1239|Firmicutes,24ICM@186801|Clostridia,21Z0G@1506553|Lachnoclostridium	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	vATP-synt_E
PNCOCPKN_02817	397288.C806_01357	2.68e-49	158.0	COG1436@1|root,COG1436@2|Bacteria,1VEN1@1239|Firmicutes,24K2E@186801|Clostridia,27NKU@186928|unclassified Lachnospiraceae	186801|Clostridia	C	ATP synthase (F/14-kDa) subunit	-	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
PNCOCPKN_02818	397290.C810_03102	7.44e-57	180.0	COG0636@1|root,COG0636@2|Bacteria,1VAGE@1239|Firmicutes,24RB6@186801|Clostridia,27MUF@186928|unclassified Lachnospiraceae	186801|Clostridia	C	ATP synthase subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
PNCOCPKN_02819	397288.C806_01355	9.47e-257	727.0	COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,249YV@186801|Clostridia,27KFU@186928|unclassified Lachnospiraceae	186801|Clostridia	U	V-type ATPase 116kDa subunit family	ntpI	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
PNCOCPKN_02820	1235790.C805_01468	1.22e-72	233.0	COG1527@1|root,COG1527@2|Bacteria,1U1QE@1239|Firmicutes,24A4E@186801|Clostridia	186801|Clostridia	C	Archaeal vacuolar-type H -ATPase subunit C	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
PNCOCPKN_02823	622312.ROSEINA2194_02225	1.75e-81	251.0	COG4862@1|root,COG4862@2|Bacteria	2|Bacteria	NOT	establishment of competence for transformation	mecA	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K16511	-	-	-	-	ko00000	-	-	-	MecA
PNCOCPKN_02824	585394.RHOM_11585	2.27e-14	69.3	COG1725@1|root,COG1725@2|Bacteria,1V9ZC@1239|Firmicutes,24NTW@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
PNCOCPKN_02826	585394.RHOM_11420	3.13e-174	501.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,24YIP@186801|Clostridia	186801|Clostridia	G	hydrolase, family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
PNCOCPKN_02828	585394.RHOM_11675	7.58e-121	355.0	29TA1@1|root,30EH1@2|Bacteria,1V43N@1239|Firmicutes,24IGU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02829	585394.RHOM_11680	1.52e-120	344.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia	186801|Clostridia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
PNCOCPKN_02830	622312.ROSEINA2194_04229	8.07e-297	811.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
PNCOCPKN_02831	585394.RHOM_11690	9.49e-175	500.0	COG4641@1|root,COG4641@2|Bacteria,1UYE0@1239|Firmicutes,24D1Q@186801|Clostridia	186801|Clostridia	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
PNCOCPKN_02832	585394.RHOM_11695	6.42e-221	618.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PNCOCPKN_02833	585394.RHOM_11700	6.55e-215	615.0	COG0845@1|root,COG0845@2|Bacteria,1UZ3U@1239|Firmicutes,24BV7@186801|Clostridia	186801|Clostridia	M	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
PNCOCPKN_02834	585394.RHOM_11705	1.68e-136	389.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PNCOCPKN_02835	585394.RHOM_11710	1.83e-161	473.0	COG0845@1|root,COG0845@2|Bacteria,1V046@1239|Firmicutes,24ANJ@186801|Clostridia	186801|Clostridia	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
PNCOCPKN_02839	585394.RHOM_03830	1.78e-290	806.0	COG1404@1|root,COG1404@2|Bacteria,1TQE0@1239|Firmicutes,25B1A@186801|Clostridia	186801|Clostridia	O	COG COG1404 Subtilisin-like serine proteases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
PNCOCPKN_02840	622312.ROSEINA2194_01915	3.05e-47	180.0	COG0840@1|root,COG5000@1|root,COG0840@2|Bacteria,COG5000@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal,dCache_1
PNCOCPKN_02841	585394.RHOM_03825	3.19e-282	783.0	COG1219@1|root,COG1219@2|Bacteria,1TPDI@1239|Firmicutes,24AEG@186801|Clostridia	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX_1	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
PNCOCPKN_02843	622312.ROSEINA2194_00348	5.11e-155	439.0	COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,24BQA@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
PNCOCPKN_02844	585394.RHOM_03805	7.34e-222	612.0	COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,248GA@186801|Clostridia	186801|Clostridia	G	2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
PNCOCPKN_02845	585394.RHOM_03800	1.1e-90	266.0	COG0537@1|root,COG0537@2|Bacteria,1V3BE@1239|Firmicutes,24H73@186801|Clostridia	186801|Clostridia	FG	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HIT
PNCOCPKN_02846	622312.ROSEINA2194_00584	1.28e-68	208.0	2ANER@1|root,315MJ@2|Bacteria,1V6SU@1239|Firmicutes,24JBZ@186801|Clostridia	186801|Clostridia	S	Stage V sporulation protein AE	spoVAE	-	-	ko:K06407	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
PNCOCPKN_02847	585394.RHOM_03740	2.79e-191	536.0	COG0183@1|root,COG0183@2|Bacteria,1UHVW@1239|Firmicutes,248BM@186801|Clostridia	186801|Clostridia	I	stage v sporulation protein ad	spoVAD	-	-	ko:K06406	-	-	-	-	ko00000	-	-	-	SpoVAD
PNCOCPKN_02849	622312.ROSEINA2194_00581	7.97e-37	129.0	COG1476@1|root,COG1476@2|Bacteria,1VCHW@1239|Firmicutes,24TP0@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02850	622312.ROSEINA2194_03332	6.16e-225	643.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia	186801|Clostridia	M	ErfK YbiS YcfS YnhG	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
PNCOCPKN_02851	585394.RHOM_11030	1.51e-128	369.0	COG0671@1|root,COG0671@2|Bacteria,1V2ZH@1239|Firmicutes,24HRY@186801|Clostridia	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,PAP2_3
PNCOCPKN_02852	1408324.JNJK01000005_gene1128	2.87e-193	549.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,27JK2@186928|unclassified Lachnospiraceae	186801|Clostridia	F	Amidohydrolase family	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
PNCOCPKN_02853	622312.ROSEINA2194_03329	4.65e-259	712.0	COG1453@1|root,COG1453@2|Bacteria,1TQ5N@1239|Firmicutes,247SD@186801|Clostridia	186801|Clostridia	C	aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
PNCOCPKN_02854	622312.ROSEINA2194_03328	0.0	1027.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
PNCOCPKN_02855	622312.ROSEINA2194_03327	1.11e-169	478.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,24940@186801|Clostridia	186801|Clostridia	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
PNCOCPKN_02856	585394.RHOM_04475	2.96e-128	371.0	COG4976@1|root,COG4976@2|Bacteria,1UHZM@1239|Firmicutes,24A6U@186801|Clostridia	186801|Clostridia	S	Methyltransferase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
PNCOCPKN_02857	585394.RHOM_04470	1.23e-183	519.0	28JB6@1|root,2Z960@2|Bacteria,1U83T@1239|Firmicutes,24BAY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02858	585394.RHOM_04465	1.46e-101	295.0	COG0440@1|root,COG0440@2|Bacteria,1V3PG@1239|Firmicutes,24A0D@186801|Clostridia	186801|Clostridia	E	acetolactate synthase, small	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
PNCOCPKN_02859	585394.RHOM_04460	0.0	1078.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia	186801|Clostridia	H	Acetolactate synthase, large subunit	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PNCOCPKN_02860	585394.RHOM_04455	1.56e-194	543.0	COG0679@1|root,COG0679@2|Bacteria,1TR9W@1239|Firmicutes,24AQF@186801|Clostridia	186801|Clostridia	S	Transporter, auxin efflux carrier (AEC) family protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
PNCOCPKN_02861	585394.RHOM_04450	5.97e-98	286.0	COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,24FTH@186801|Clostridia	186801|Clostridia	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
PNCOCPKN_02862	585394.RHOM_04440	2.66e-30	108.0	2DRX4@1|root,33DGR@2|Bacteria,1VKQ3@1239|Firmicutes,24URP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02863	585394.RHOM_04435	5.16e-67	207.0	COG3976@1|root,COG3976@2|Bacteria,1V72R@1239|Firmicutes,24JFD@186801|Clostridia	186801|Clostridia	S	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02864	1469948.JPNB01000001_gene446	3.3e-143	444.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,36E1W@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,dCache_1
PNCOCPKN_02867	562743.JH976434_gene1893	1.24e-208	606.0	COG0419@1|root,COG0419@2|Bacteria,1TSW9@1239|Firmicutes	1239|Firmicutes	L	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF3732
PNCOCPKN_02869	562743.JH976434_gene1895	1.45e-105	324.0	2B6ZF@1|root,31ZZQ@2|Bacteria,1VIW5@1239|Firmicutes,4HXXT@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02872	1128111.HMPREF0870_00983	3.39e-38	135.0	COG2856@1|root,COG2856@2|Bacteria,1VN20@1239|Firmicutes	1239|Firmicutes	E	Pfam:DUF955	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
PNCOCPKN_02873	877418.ATWV01000006_gene2261	1.75e-24	97.1	COG1426@1|root,COG1426@2|Bacteria,2J92W@203691|Spirochaetes	203691|Spirochaetes	K	helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19
PNCOCPKN_02874	397291.C804_01109	3.62e-40	150.0	COG3584@1|root,COG3772@1|root,COG3584@2|Bacteria,COG3772@2|Bacteria,1VG3D@1239|Firmicutes,25KGI@186801|Clostridia,27QPE@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Phage lysozyme	-	-	-	-	-	-	-	-	-	-	-	-	Phage_lysozyme
PNCOCPKN_02875	742723.HMPREF9477_00889	1.59e-33	122.0	COG4824@1|root,COG4824@2|Bacteria,1V81B@1239|Firmicutes,24JF5@186801|Clostridia,27QEX@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Bacteriophage holin family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_1
PNCOCPKN_02877	1298920.KI911353_gene4834	7.67e-14	65.1	2DCJE@1|root,2ZEDW@2|Bacteria,1W6F3@1239|Firmicutes,25JUF@186801|Clostridia,223KG@1506553|Lachnoclostridium	186801|Clostridia	S	Phage uncharacterised protein (Phage_XkdX)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_XkdX
PNCOCPKN_02879	1235793.C809_01950	1.02e-08	64.3	COG5301@1|root,COG5301@2|Bacteria,1UW61@1239|Firmicutes,25APV@186801|Clostridia,27SBS@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Phage tail-collar fibre protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3751
PNCOCPKN_02881	397288.C806_00059	4.54e-99	304.0	COG3299@1|root,COG3299@2|Bacteria,1TQZU@1239|Firmicutes,249WP@186801|Clostridia,27K7C@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
PNCOCPKN_02882	665950.HMPREF1025_01340	3.66e-24	97.4	COG3628@1|root,COG3628@2|Bacteria,1UJW5@1239|Firmicutes,25FBV@186801|Clostridia,27Q2R@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF2634)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2634
PNCOCPKN_02884	1408324.JNJK01000006_gene1393	7.16e-92	286.0	COG0791@1|root,COG0791@2|Bacteria,1V42E@1239|Firmicutes,24FF0@186801|Clostridia,27NC7@186928|unclassified Lachnospiraceae	186801|Clostridia	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,NLPC_P60
PNCOCPKN_02885	1095750.HMPREF9970_2278	1.99e-22	97.8	COG1652@1|root,COG1652@2|Bacteria,1V1BA@1239|Firmicutes,24MKW@186801|Clostridia	186801|Clostridia	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
PNCOCPKN_02886	1095750.HMPREF9970_2277	2.95e-151	465.0	COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,1HWG2@1164882|Lachnoanaerobaculum	186801|Clostridia	S	Phage-related minor tail protein	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
PNCOCPKN_02888	397288.C806_00066	1.53e-36	129.0	2EQRS@1|root,33IBM@2|Bacteria,1VPTM@1239|Firmicutes,25ICK@186801|Clostridia,27S3H@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Phage XkdN-like tail assembly chaperone protein, TAC	-	-	-	-	-	-	-	-	-	-	-	-	Phage_TAC_5
PNCOCPKN_02889	1408324.JNJK01000006_gene1388	4.56e-66	204.0	2DKUN@1|root,30DF7@2|Bacteria,1VAF1@1239|Firmicutes,24GEC@186801|Clostridia	186801|Clostridia	S	Phage tail tube protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2001
PNCOCPKN_02890	1408324.JNJK01000006_gene1387	1.24e-151	437.0	28ISD@1|root,2Z8RJ@2|Bacteria,1TQJ7@1239|Firmicutes,2499A@186801|Clostridia,27MUV@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Phage tail sheath C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_sheath_1,Phage_sheath_1C
PNCOCPKN_02894	632245.CLP_2916	5.79e-13	66.2	2C51R@1|root,2ZHBZ@2|Bacteria,1W22Q@1239|Firmicutes,24UFX@186801|Clostridia,36N4W@31979|Clostridiaceae	186801|Clostridia	S	Phage gp6-like head-tail connector protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_connect_1
PNCOCPKN_02895	397288.C806_00073	2.2e-124	372.0	COG4653@1|root,COG4653@2|Bacteria,1TS6A@1239|Firmicutes,24994@186801|Clostridia	186801|Clostridia	S	phage major capsid protein, HK97 family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
PNCOCPKN_02896	1414720.CBYM010000002_gene573	6.85e-51	170.0	COG3740@1|root,COG3740@2|Bacteria,1VUUG@1239|Firmicutes,24HV8@186801|Clostridia,36KTQ@31979|Clostridiaceae	186801|Clostridia	S	Phage prohead protease, HK97 family	-	-	-	ko:K06904	-	-	-	-	ko00000	-	-	-	Peptidase_S78
PNCOCPKN_02897	397288.C806_00075	3.33e-125	376.0	COG4695@1|root,COG4695@2|Bacteria	2|Bacteria	N	Portal protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal
PNCOCPKN_02898	1414720.CBYM010000002_gene575	4.12e-250	704.0	COG4626@1|root,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,248RI@186801|Clostridia,36E5Y@31979|Clostridiaceae	186801|Clostridia	S	Terminase	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_1
PNCOCPKN_02899	397288.C806_00077	2.71e-33	125.0	29979@1|root,2ZWAK@2|Bacteria,1W5BZ@1239|Firmicutes,24X6R@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02900	397288.C806_00078	3.92e-16	74.7	29X9K@1|root,30IZ3@2|Bacteria,1UJW6@1239|Firmicutes,24PGD@186801|Clostridia	186801|Clostridia	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
PNCOCPKN_02909	483218.BACPEC_01163	6.6e-117	337.0	COG1961@1|root,COG1961@2|Bacteria,1TQAX@1239|Firmicutes,24B05@186801|Clostridia,268HG@186813|unclassified Clostridiales	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
PNCOCPKN_02913	622312.ROSEINA2194_04464	4.32e-42	154.0	28HI8@1|root,2Z7TS@2|Bacteria,1TQTK@1239|Firmicutes,249WK@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4317
PNCOCPKN_02914	585394.RHOM_04340	3.21e-44	156.0	28HI8@1|root,2Z7TS@2|Bacteria,1TQTK@1239|Firmicutes,249WK@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4317
PNCOCPKN_02916	1235800.C819_02254	2e-31	115.0	2EVQ5@1|root,33P45@2|Bacteria,1VNBK@1239|Firmicutes,24WVK@186801|Clostridia	186801|Clostridia	S	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02917	1280698.AUJS01000007_gene1019	9.41e-60	209.0	2EAE3@1|root,334HP@2|Bacteria,1VHM2@1239|Firmicutes,24K95@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02918	97139.C824_00039	1.33e-66	236.0	28KSN@1|root,31D8D@2|Bacteria,1V6SJ@1239|Firmicutes,24BTZ@186801|Clostridia,36SHV@31979|Clostridiaceae	186801|Clostridia	S	PcfJ-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PcfJ
PNCOCPKN_02919	1235792.C808_00065	7.93e-64	200.0	2F1A0@1|root,33UB0@2|Bacteria,1VUUK@1239|Firmicutes,24Q4U@186801|Clostridia,27RY5@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02920	696369.KI912183_gene127	2.41e-09	60.1	COG0328@1|root,COG0328@2|Bacteria,1V4A0@1239|Firmicutes,24FSS@186801|Clostridia,26219@186807|Peptococcaceae	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
PNCOCPKN_02921	1235800.C819_02258	1.15e-84	261.0	2APHD@1|root,31EKC@2|Bacteria,1V7GX@1239|Firmicutes,24GBC@186801|Clostridia,27PAK@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02930	1280698.AUJS01000007_gene1002	1.21e-32	119.0	COG1396@1|root,COG1396@2|Bacteria,1VEU8@1239|Firmicutes,24QN0@186801|Clostridia,27VXX@189330|Dorea	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
PNCOCPKN_02932	537013.CLOSTMETH_02498	8.48e-94	288.0	COG0272@1|root,COG2176@1|root,COG0272@2|Bacteria,COG2176@2|Bacteria,1TRS5@1239|Firmicutes,24ER5@186801|Clostridia	186801|Clostridia	L	EXOIII	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	BRCT,RNase_T,zf-C4_Topoisom
PNCOCPKN_02933	537013.CLOSTMETH_00282	6.94e-31	110.0	COG2026@1|root,COG2026@2|Bacteria,1UHB7@1239|Firmicutes,24T4T@186801|Clostridia,3WMC8@541000|Ruminococcaceae	186801|Clostridia	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
PNCOCPKN_02934	658086.HMPREF0994_03676	2.12e-22	88.2	2CBNP@1|root,325WZ@2|Bacteria,1URWV@1239|Firmicutes,259UF@186801|Clostridia,27Q7M@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02938	1304866.K413DRAFT_1180	4.71e-116	347.0	COG0582@1|root,COG0582@2|Bacteria,1V16B@1239|Firmicutes,24CY2@186801|Clostridia,36QAA@31979|Clostridiaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
PNCOCPKN_02940	1235794.C811_00133	5.87e-79	273.0	COG3420@1|root,COG5434@1|root,COG3420@2|Bacteria,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Beta_helix,Big_2,Big_5,DUF3494,Pectate_lyase_3
PNCOCPKN_02942	622312.ROSEINA2194_03097	0.0	1107.0	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,2492T@186801|Clostridia	186801|Clostridia	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
PNCOCPKN_02944	1235799.C818_02957	2.58e-74	259.0	COG1368@1|root,COG1368@2|Bacteria,1VI7Z@1239|Firmicutes,24QYG@186801|Clostridia,27PIR@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
PNCOCPKN_02945	1235802.C823_06083	3.03e-14	73.6	COG5433@1|root,COG5433@2|Bacteria,1V0JK@1239|Firmicutes,249XC@186801|Clostridia	186801|Clostridia	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
PNCOCPKN_02946	1235802.C823_02123	2.88e-149	432.0	COG0451@1|root,COG0451@2|Bacteria,1TS59@1239|Firmicutes,247JP@186801|Clostridia,25W52@186806|Eubacteriaceae	186801|Clostridia	GM	NAD dependent epimerase dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
PNCOCPKN_02947	1235802.C823_02122	1.34e-148	422.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,25W5N@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate	-	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,adh_short
PNCOCPKN_02948	478749.BRYFOR_07393	4.89e-119	362.0	COG1134@1|root,COG4641@1|root,COG1134@2|Bacteria,COG4641@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia	186801|Clostridia	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	rfbB	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PNCOCPKN_02949	411489.CLOL250_00069	1.61e-114	336.0	COG1682@1|root,COG1682@2|Bacteria,1V1J2@1239|Firmicutes,25B57@186801|Clostridia,36WAG@31979|Clostridiaceae	186801|Clostridia	GM	Transport permease protein	-	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
PNCOCPKN_02950	1499684.CCNP01000025_gene3497	4.04e-90	285.0	COG1887@1|root,COG1887@2|Bacteria,1TP75@1239|Firmicutes,24ED0@186801|Clostridia,36FYJ@31979|Clostridiaceae	186801|Clostridia	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	-	-	2.7.8.12	ko:K09809	-	-	-	-	ko00000,ko01000	-	-	-	Glyphos_transf
PNCOCPKN_02951	553973.CLOHYLEM_06254	1.8e-38	143.0	COG3475@1|root,COG3475@2|Bacteria,1VBSV@1239|Firmicutes,24C5H@186801|Clostridia,2246C@1506553|Lachnoclostridium	186801|Clostridia	M	LicD family	licD	-	-	ko:K07271	-	-	-	-	ko00000,ko01000	-	-	-	LicD
PNCOCPKN_02952	1235802.C823_02121	2.1e-227	648.0	COG1887@1|root,COG1887@2|Bacteria,1TSTN@1239|Firmicutes,24AA5@186801|Clostridia,25VZJ@186806|Eubacteriaceae	186801|Clostridia	M	teichoic acid biosynthesis protein B	-	-	2.7.8.14,2.7.8.47	ko:K18704	-	-	R11614,R11621	-	ko00000,ko01000	-	-	-	Glycos_transf_2,Glyphos_transf
PNCOCPKN_02953	1235793.C809_00275	3.15e-71	227.0	COG3385@1|root,COG3385@2|Bacteria,1TY08@1239|Firmicutes,24EQW@186801|Clostridia,27JJD@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
PNCOCPKN_02954	622312.ROSEINA2194_03927	1.33e-253	729.0	COG3501@1|root,COG3501@2|Bacteria,1V3I5@1239|Firmicutes,24GKG@186801|Clostridia	186801|Clostridia	F	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
PNCOCPKN_02955	622312.ROSEINA2194_01398	6.12e-121	348.0	COG5620@1|root,COG5620@2|Bacteria,1V5S8@1239|Firmicutes,24K3Z@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF1851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1851,GAD-like
PNCOCPKN_02956	622312.ROSEINA2194_04022	4.13e-71	224.0	COG3385@1|root,COG3385@2|Bacteria,1TSH6@1239|Firmicutes,24A21@186801|Clostridia	186801|Clostridia	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
PNCOCPKN_02957	1410638.JHXJ01000001_gene1725	1.16e-101	299.0	COG0286@1|root,COG0286@2|Bacteria,1V60T@1239|Firmicutes,24I05@186801|Clostridia,3WMIZ@541000|Ruminococcaceae	186801|Clostridia	V	site-specific DNA-methyltransferase (adenine-specific) activity	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02958	622312.ROSEINA2194_01633	2.29e-66	212.0	COG3209@1|root,COG3209@2|Bacteria,1V5PZ@1239|Firmicutes	1239|Firmicutes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS,RHS_repeat
PNCOCPKN_02959	1285586.H131_00990	3.03e-70	218.0	2EISZ@1|root,33CIA@2|Bacteria,1VQG5@1239|Firmicutes,4HVKT@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02960	622312.ROSEINA2194_01637	4.29e-70	213.0	COG3385@1|root,COG3385@2|Bacteria,1TSH6@1239|Firmicutes,24A21@186801|Clostridia	186801|Clostridia	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
PNCOCPKN_02961	622312.ROSEINA2194_01638	4.01e-84	247.0	2E5DE@1|root,3305E@2|Bacteria,1VJ7G@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1851
PNCOCPKN_02962	622312.ROSEINA2194_03933	1.11e-69	214.0	2E4BD@1|root,32Z71@2|Bacteria,1VFIN@1239|Firmicutes,24NQT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02963	622312.ROSEINA2194_01641	4.72e-71	218.0	COG3279@1|root,COG3279@2|Bacteria,1V1JI@1239|Firmicutes,25BT0@186801|Clostridia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
PNCOCPKN_02964	515620.EUBELI_00242	4.94e-67	229.0	COG3475@1|root,COG3475@2|Bacteria,1VBSV@1239|Firmicutes,24C5H@186801|Clostridia,25XKH@186806|Eubacteriaceae	186801|Clostridia	M	LicD family	-	-	-	-	-	-	-	-	-	-	-	-	LicD
PNCOCPKN_02966	1235802.C823_01173	1.38e-83	265.0	COG1442@1|root,COG1442@2|Bacteria,1U6EG@1239|Firmicutes,24B83@186801|Clostridia,25UTV@186806|Eubacteriaceae	186801|Clostridia	M	Domain of unknown function (DUF4422)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4422,Glyco_transf_8
PNCOCPKN_02967	585394.RHOM_00730	1.38e-153	456.0	COG4641@1|root,COG4641@2|Bacteria,1UMWB@1239|Firmicutes,24CQX@186801|Clostridia	186801|Clostridia	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
PNCOCPKN_02968	397287.C807_02861	9.78e-79	249.0	COG3475@1|root,COG3475@2|Bacteria,1VBSV@1239|Firmicutes,24C5H@186801|Clostridia,27T8Q@186928|unclassified Lachnospiraceae	186801|Clostridia	M	LicD family	-	-	-	-	-	-	-	-	-	-	-	-	LicD
PNCOCPKN_02969	585394.RHOM_00825	2.45e-103	306.0	COG0500@1|root,COG2226@2|Bacteria,1VV2D@1239|Firmicutes	1239|Firmicutes	Q	Methyltransferase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
PNCOCPKN_02970	585394.RHOM_00830	1.45e-312	865.0	COG0079@1|root,COG1213@1|root,COG0079@2|Bacteria,COG1213@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia	186801|Clostridia	E	PFAM Aminotransferase class I and II	-	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2,NTP_transf_3
PNCOCPKN_02971	1280680.AUJU01000031_gene3595	8.23e-98	290.0	COG0237@1|root,COG0237@2|Bacteria,1VHNA@1239|Firmicutes,24KBU@186801|Clostridia,4BW2U@830|Butyrivibrio	186801|Clostridia	H	dephospho-CoA kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02972	573061.Clocel_1643	4.1e-121	352.0	COG2820@1|root,COG2820@2|Bacteria,1UFD2@1239|Firmicutes,24ICS@186801|Clostridia	186801|Clostridia	F	Phosphorylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
PNCOCPKN_02974	622312.ROSEINA2194_00603	2.16e-82	249.0	COG0127@1|root,COG0127@2|Bacteria,1V85S@1239|Firmicutes,24KX4@186801|Clostridia	186801|Clostridia	F	Ham1 family	-	-	-	-	-	-	-	-	-	-	-	-	Ham1p_like
PNCOCPKN_02975	352165.HMPREF7215_0139	4.63e-43	154.0	COG2265@1|root,COG2265@2|Bacteria,3TAIZ@508458|Synergistetes	508458|Synergistetes	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
PNCOCPKN_02976	1235802.C823_01849	6.17e-201	556.0	2B2S0@1|root,31VC8@2|Bacteria,1V9PV@1239|Firmicutes,24KT4@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4263)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4263
PNCOCPKN_02977	1235802.C823_01848	1.25e-214	593.0	COG1715@1|root,COG1715@2|Bacteria,1VGCJ@1239|Firmicutes,24U5T@186801|Clostridia	186801|Clostridia	V	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Mrr_cat
PNCOCPKN_02979	1239962.C943_04226	8.22e-50	176.0	COG5635@1|root,COG5635@2|Bacteria,4NIRY@976|Bacteroidetes,47T6P@768503|Cytophagia	976|Bacteroidetes	T	NACHT domain	-	-	-	-	-	-	-	-	-	-	-	-	NACHT
PNCOCPKN_02980	622312.ROSEINA2194_03562	5.45e-61	187.0	COG2963@1|root,COG2963@2|Bacteria,1VCC9@1239|Firmicutes,24MCM@186801|Clostridia	186801|Clostridia	L	PFAM transposase IS3 IS911 family protein	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_Tnp_1
PNCOCPKN_02983	96561.Dole_3086	2.32e-123	414.0	COG0433@1|root,COG0433@2|Bacteria,1RBH9@1224|Proteobacteria	1224|Proteobacteria	S	COG0433 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02985	1280686.AUKE01000031_gene1554	4.06e-58	184.0	COG0454@1|root,COG0456@2|Bacteria,1VAQ8@1239|Firmicutes,24KVY@186801|Clostridia	186801|Clostridia	K	Acetyltransferase (GNAT) family	-	-	2.3.1.82	ko:K18816	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
PNCOCPKN_02986	511680.BUTYVIB_02389	9.95e-129	365.0	COG0655@1|root,COG0655@2|Bacteria,1UHW0@1239|Firmicutes,24N5N@186801|Clostridia,4BZ31@830|Butyrivibrio	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
PNCOCPKN_02987	500632.CLONEX_00872	0.0	1043.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,2481D@186801|Clostridia	186801|Clostridia	U	Relaxase mobilization nuclease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
PNCOCPKN_02988	500632.CLONEX_00871	9.24e-85	250.0	29KXV@1|root,307VB@2|Bacteria,1V5JW@1239|Firmicutes,24HAU@186801|Clostridia	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
PNCOCPKN_02990	500632.CLONEX_00865	1.39e-130	371.0	COG1396@1|root,COG1396@2|Bacteria,1V9ZU@1239|Firmicutes	1239|Firmicutes	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PNCOCPKN_02991	500632.CLONEX_00864	7.09e-299	816.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
PNCOCPKN_02992	742735.HMPREF9467_05194	3.42e-77	230.0	COG3436@1|root,COG3436@2|Bacteria,1V7U9@1239|Firmicutes,24K4W@186801|Clostridia	186801|Clostridia	L	PFAM IS66 Orf2	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
PNCOCPKN_02993	1469948.JPNB01000001_gene2433	5.46e-99	308.0	COG0642@1|root,COG0642@2|Bacteria,1UK4T@1239|Firmicutes,25FK0@186801|Clostridia	186801|Clostridia	T	signal transduction protein with a C-terminal ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
PNCOCPKN_02994	1469948.JPNB01000001_gene2434	2.12e-61	200.0	COG3279@1|root,COG3279@2|Bacteria,1V0DF@1239|Firmicutes,24J7N@186801|Clostridia,36KGJ@31979|Clostridiaceae	186801|Clostridia	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
PNCOCPKN_02995	622312.ROSEINA2194_03562	1.97e-63	193.0	COG2963@1|root,COG2963@2|Bacteria,1VCC9@1239|Firmicutes,24MCM@186801|Clostridia	186801|Clostridia	L	PFAM transposase IS3 IS911 family protein	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_Tnp_1
PNCOCPKN_02996	411470.RUMGNA_01472	5.99e-213	588.0	COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,24DGQ@186801|Clostridia,3Y2AQ@572511|Blautia	186801|Clostridia	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
PNCOCPKN_02997	1469948.JPNB01000001_gene2416	1.95e-32	122.0	COG4512@1|root,COG4512@2|Bacteria,1VKH5@1239|Firmicutes,24QIQ@186801|Clostridia,36P2J@31979|Clostridiaceae	186801|Clostridia	KOT	PFAM Accessory gene regulator B	-	-	-	ko:K07813	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	AgrB
PNCOCPKN_02998	1235802.C823_05468	7.48e-63	207.0	28MNT@1|root,2ZAY9@2|Bacteria,1UJWE@1239|Firmicutes,248QQ@186801|Clostridia,25Y7H@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_02999	483218.BACPEC_02745	2.5e-84	251.0	COG1132@1|root,COG1132@2|Bacteria,1US0C@1239|Firmicutes,24EZJ@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
PNCOCPKN_03000	622312.ROSEINA2194_02825	1.16e-127	373.0	COG3039@1|root,COG3039@2|Bacteria,1TSDW@1239|Firmicutes,249M5@186801|Clostridia	186801|Clostridia	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF772
PNCOCPKN_03001	585394.RHOM_15595	2.74e-63	204.0	COG3505@1|root,COG3505@2|Bacteria,1UVIR@1239|Firmicutes,24E4K@186801|Clostridia	186801|Clostridia	U	COG3505 Type IV secretory pathway, VirD4 components	-	-	-	-	-	-	-	-	-	-	-	-	T4SS-DNA_transf
PNCOCPKN_03003	622312.ROSEINA2194_04286	1.83e-188	523.0	COG3267@1|root,COG3267@2|Bacteria,1TRGM@1239|Firmicutes,24EPV@186801|Clostridia	186801|Clostridia	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
PNCOCPKN_03004	622312.ROSEINA2194_04287	2.72e-301	821.0	COG2801@1|root,COG2801@2|Bacteria,1TQH6@1239|Firmicutes,249ZV@186801|Clostridia	186801|Clostridia	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_32,Mu-transpos_C,rve
PNCOCPKN_03006	1235790.C805_01077	4.17e-82	250.0	COG2088@1|root,COG2088@2|Bacteria,1V19U@1239|Firmicutes,249EY@186801|Clostridia,25WDB@186806|Eubacteriaceae	186801|Clostridia	D	protein, involved in the regulation of septum location	-	-	-	-	-	-	-	-	-	-	-	-	SpoVG
PNCOCPKN_03007	596323.HMPREF0554_0059	4.45e-18	87.0	COG3593@1|root,COG3593@2|Bacteria	2|Bacteria	L	DNA synthesis involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15
PNCOCPKN_03008	411463.EUBVEN_01883	2.11e-161	452.0	COG0494@1|root,COG3655@1|root,COG0494@2|Bacteria,COG3655@2|Bacteria,1UHU0@1239|Firmicutes,25F22@186801|Clostridia,25ZJK@186806|Eubacteriaceae	186801|Clostridia	L	COG COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
PNCOCPKN_03009	190304.FN1445	0.0	1350.0	COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,37B56@32066|Fusobacteria	32066|Fusobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF2726
PNCOCPKN_03010	511680.BUTYVIB_02387	2.6e-130	371.0	COG0406@1|root,COG0406@2|Bacteria,1V3RC@1239|Firmicutes,24GHZ@186801|Clostridia,4BYF3@830|Butyrivibrio	186801|Clostridia	G	Histidine phosphatase superfamily (branch 1)	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
PNCOCPKN_03011	511680.BUTYVIB_02388	5.44e-73	221.0	COG0454@1|root,COG0456@2|Bacteria,1VAJN@1239|Firmicutes,24H93@186801|Clostridia,4BZ8X@830|Butyrivibrio	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
PNCOCPKN_03012	585394.RHOM_15945	2.24e-93	283.0	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03013	585394.RHOM_09375	1.64e-51	168.0	2AKH0@1|root,31B8X@2|Bacteria,1V6ZY@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF2975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
PNCOCPKN_03014	1235790.C805_03566	9.31e-34	117.0	COG3655@1|root,COG3655@2|Bacteria,1VESP@1239|Firmicutes,24QSQ@186801|Clostridia,25XC8@186806|Eubacteriaceae	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
PNCOCPKN_03015	585394.RHOM_09365	4.48e-125	382.0	COG0810@1|root,COG0810@2|Bacteria,1UJMR@1239|Firmicutes,251BT@186801|Clostridia	186801|Clostridia	M	Domain of unknown function (DUF4173)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4173
PNCOCPKN_03016	585394.RHOM_10170	5.2e-198	559.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248IH@186801|Clostridia	186801|Clostridia	S	ABC-type transport system, periplasmic component surface lipoprotein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
PNCOCPKN_03017	483218.BACPEC_02957	2.24e-143	433.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,26BFA@186813|unclassified Clostridiales	186801|Clostridia	NT	Single cache domain 3	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,sCache_3_3
PNCOCPKN_03018	622312.ROSEINA2194_01368	1.55e-78	238.0	COG1051@1|root,COG1051@2|Bacteria,1UUZ0@1239|Firmicutes,24NDR@186801|Clostridia	186801|Clostridia	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
PNCOCPKN_03019	585394.RHOM_09310	3.39e-98	286.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia	186801|Clostridia	G	methylglyoxal synthase	mgsA	-	2.7.1.24,4.2.3.3	ko:K00859,ko:K01734	ko00640,ko00770,ko01100,ko01120,map00640,map00770,map01100,map01120	M00120	R00130,R01016	RC00002,RC00078,RC00424	ko00000,ko00001,ko00002,ko01000	-	-	-	MGS
PNCOCPKN_03020	585394.RHOM_09305	3.52e-178	499.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,248N9@186801|Clostridia	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
PNCOCPKN_03021	585394.RHOM_09300	1.82e-245	683.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PNCOCPKN_03022	585394.RHOM_09295	2.08e-149	427.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia	186801|Clostridia	K	lysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PNCOCPKN_03023	1256908.HMPREF0373_01084	5.64e-297	811.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,25V6G@186806|Eubacteriaceae	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
PNCOCPKN_03024	585394.RHOM_09285	9.36e-76	233.0	COG1011@1|root,COG1011@2|Bacteria,1V6I4@1239|Firmicutes,24JK7@186801|Clostridia	186801|Clostridia	S	HAD hydrolase, family IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
PNCOCPKN_03025	585394.RHOM_09280	1.73e-144	416.0	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,25AZ1@186801|Clostridia	186801|Clostridia	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PNCOCPKN_03026	585394.RHOM_09275	0.0	904.0	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria,1TT1J@1239|Firmicutes,24BC2@186801|Clostridia	186801|Clostridia	N	-transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3,ABC_transp_aux
PNCOCPKN_03029	1256908.HMPREF0373_01181	2.76e-244	680.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,25VD8@186806|Eubacteriaceae	186801|Clostridia	C	citrate synthase	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
PNCOCPKN_03030	622312.ROSEINA2194_00357	1.81e-29	106.0	2DR14@1|root,339R7@2|Bacteria,1VMNT@1239|Firmicutes,24UVM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03031	585394.RHOM_09245	1.72e-112	323.0	COG3012@1|root,COG3012@2|Bacteria,1V1CC@1239|Firmicutes,24FYC@186801|Clostridia	186801|Clostridia	U	Psort location Cytoplasmic, score	secA_2	-	-	-	-	-	-	-	-	-	-	-	SEC-C
PNCOCPKN_03033	585394.RHOM_09240	2.92e-45	148.0	2DP3R@1|root,330E2@2|Bacteria,1VEPT@1239|Firmicutes,24QJB@186801|Clostridia	186801|Clostridia	S	COG NOG16856 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF1540
PNCOCPKN_03034	585394.RHOM_09230	5.85e-87	261.0	2C6U1@1|root,30XIE@2|Bacteria,1V4EP@1239|Firmicutes,24J3E@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
PNCOCPKN_03037	585394.RHOM_09220	1.49e-93	273.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia	186801|Clostridia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
PNCOCPKN_03038	622312.ROSEINA2194_01247	3.2e-196	547.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
PNCOCPKN_03039	622312.ROSEINA2194_01246	4.57e-60	191.0	2E3U8@1|root,32YRK@2|Bacteria,1VEYB@1239|Firmicutes,24QRX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
PNCOCPKN_03040	585394.RHOM_09205	0.0	1049.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia	186801|Clostridia	M	penicillin-binding protein	-	-	-	ko:K08384	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PBP_dimer,Transpeptidase
PNCOCPKN_03041	585394.RHOM_09200	0.0	934.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia	186801|Clostridia	M	penicillin-binding protein	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
PNCOCPKN_03042	585394.RHOM_09195	1.71e-198	553.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia	186801|Clostridia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
PNCOCPKN_03043	585394.RHOM_09190	3.3e-192	548.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
PNCOCPKN_03044	585394.RHOM_09185	4.55e-203	569.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
PNCOCPKN_03045	585394.RHOM_09180	3.1e-119	347.0	COG1589@1|root,COG1589@2|Bacteria,1V34X@1239|Firmicutes,248RF@186801|Clostridia	186801|Clostridia	M	COG1589 Cell division septal protein	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
PNCOCPKN_03046	585394.RHOM_09175	1.55e-231	643.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
PNCOCPKN_03047	742741.HMPREF9475_01248	3.45e-11	68.2	29ECG@1|root,301AF@2|Bacteria,1UY4W@1239|Firmicutes,24HI3@186801|Clostridia,21YX0@1506553|Lachnoclostridium	186801|Clostridia	M	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR	spoIIGA	-	-	ko:K06383	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_U4
PNCOCPKN_03048	622312.ROSEINA2194_01236	6.18e-130	374.0	COG1191@1|root,COG1191@2|Bacteria,1TP3T@1239|Firmicutes,24A4T@186801|Clostridia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigE	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
PNCOCPKN_03049	622312.ROSEINA2194_01235	0.0	907.0	COG1236@1|root,COG1236@2|Bacteria,1TQBH@1239|Firmicutes,248QR@186801|Clostridia	186801|Clostridia	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
PNCOCPKN_03050	585394.RHOM_09155	4.61e-158	446.0	COG1191@1|root,COG1191@2|Bacteria,1TPDD@1239|Firmicutes,24A1H@186801|Clostridia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigG	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
PNCOCPKN_03052	585394.RHOM_09140	6.68e-155	440.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24B81@186801|Clostridia	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF_2	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
PNCOCPKN_03054	585394.RHOM_08785	3.34e-307	862.0	COG0451@1|root,COG0451@2|Bacteria,1UYUX@1239|Firmicutes,24CYP@186801|Clostridia	186801|Clostridia	GM	Psort location CytoplasmicMembrane, score	-	-	5.1.3.2	ko:K01784,ko:K21009	ko00052,ko00520,ko01100,ko02025,map00052,map00520,map01100,map02025	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,RmlD_sub_bind
PNCOCPKN_03055	585394.RHOM_08780	9.63e-124	363.0	28H6W@1|root,2ZA4C@2|Bacteria,1UXGN@1239|Firmicutes,24AZN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03056	411469.EUBHAL_02519	8.44e-185	555.0	28N1Z@1|root,2ZB7X@2|Bacteria,1UZID@1239|Firmicutes,24F7M@186801|Clostridia,25Y86@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03057	585394.RHOM_08775	4.34e-184	540.0	28HJQ@1|root,2Z7UU@2|Bacteria,1UPMJ@1239|Firmicutes,24BW1@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2194
PNCOCPKN_03058	585394.RHOM_08770	3.31e-244	682.0	COG0438@1|root,COG0438@2|Bacteria,1TQ8U@1239|Firmicutes,24BAM@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	ko:K21011	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	DUF3492,Glycos_transf_1
PNCOCPKN_03059	585394.RHOM_08765	4.42e-250	697.0	COG4267@1|root,COG4267@2|Bacteria,1TRZE@1239|Firmicutes,24EQ7@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K21012	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	PelG
PNCOCPKN_03060	1235802.C823_04311	1.87e-10	61.6	2EA00@1|root,3345F@2|Bacteria,1VJQ9@1239|Firmicutes,24R0V@186801|Clostridia,25Z91@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2304
PNCOCPKN_03061	585394.RHOM_08755	3.51e-166	479.0	COG0438@1|root,COG0438@2|Bacteria,1V09V@1239|Firmicutes,24C11@186801|Clostridia	186801|Clostridia	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
PNCOCPKN_03062	585394.RHOM_08750	1.09e-140	402.0	COG1216@1|root,COG1216@2|Bacteria,1UAQP@1239|Firmicutes,25B5D@186801|Clostridia	186801|Clostridia	S	group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PNCOCPKN_03063	585394.RHOM_08745	7.31e-92	290.0	28NI3@1|root,2ZBJM@2|Bacteria,1V27V@1239|Firmicutes,24FTG@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4874)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,DUF4874
PNCOCPKN_03064	411479.BACUNI_00969	4.16e-49	174.0	COG0463@1|root,COG0463@2|Bacteria,4NQ67@976|Bacteroidetes,2G06Z@200643|Bacteroidia,4AV2G@815|Bacteroidaceae	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PNCOCPKN_03065	585394.RHOM_08735	1.87e-250	701.0	COG2244@1|root,COG2244@2|Bacteria,1TR1W@1239|Firmicutes,24917@186801|Clostridia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3
PNCOCPKN_03066	585394.RHOM_08730	3.83e-140	413.0	COG2244@1|root,COG2244@2|Bacteria,1V0I3@1239|Firmicutes,24F2V@186801|Clostridia	186801|Clostridia	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
PNCOCPKN_03067	585394.RHOM_08720	4.26e-167	485.0	2DBEW@1|root,2Z8UY@2|Bacteria,1UYFJ@1239|Firmicutes,2489J@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4874)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,DUF4874
PNCOCPKN_03068	1235792.C808_02507	1.03e-167	478.0	COG1216@1|root,COG1216@2|Bacteria,1VV6P@1239|Firmicutes,25EH9@186801|Clostridia,27JXT@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PNCOCPKN_03069	97139.C824_04122	2.07e-77	236.0	2B66C@1|root,31Z3H@2|Bacteria,1V6U0@1239|Firmicutes,24ICU@186801|Clostridia,36J7Y@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03070	1235799.C818_02800	5.62e-97	298.0	COG0392@1|root,COG0392@2|Bacteria,1TXG8@1239|Firmicutes,24A1A@186801|Clostridia,27K01@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
PNCOCPKN_03071	585394.RHOM_08705	1.16e-52	169.0	2BZS0@1|root,343DQ@2|Bacteria,1VZ4U@1239|Firmicutes,25450@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03072	585394.RHOM_08700	0.0	932.0	COG1132@1|root,COG1132@2|Bacteria,1TRJF@1239|Firmicutes,249CN@186801|Clostridia	186801|Clostridia	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PNCOCPKN_03073	411469.EUBHAL_02535	2.3e-86	275.0	2DBZW@1|root,2ZC46@2|Bacteria,1V2V4@1239|Firmicutes,24H1D@186801|Clostridia	186801|Clostridia	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
PNCOCPKN_03074	1235802.C823_04319	6.48e-50	163.0	COG0681@1|root,COG0681@2|Bacteria,1VFKY@1239|Firmicutes,24RQG@186801|Clostridia,25XJH@186806|Eubacteriaceae	186801|Clostridia	U	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
PNCOCPKN_03075	1235802.C823_05151	2.67e-72	221.0	COG4708@1|root,COG4708@2|Bacteria,1V9YK@1239|Firmicutes,24N9H@186801|Clostridia,25WR7@186806|Eubacteriaceae	186801|Clostridia	S	QueT transporter	queT	-	-	-	-	-	-	-	-	-	-	-	QueT
PNCOCPKN_03076	877421.AUJT01000002_gene1161	9.69e-123	354.0	COG3010@1|root,COG3010@2|Bacteria,1TSR7@1239|Firmicutes,24AVB@186801|Clostridia,27JDF@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)	nanE	-	5.1.3.9	ko:K01788	ko00520,map00520	-	R02087	RC00290	ko00000,ko00001,ko01000	-	-	-	NanE
PNCOCPKN_03077	1111135.HMPREF1248_0984	4.66e-211	594.0	COG2610@1|root,COG2610@2|Bacteria,2I7H9@201174|Actinobacteria	201174|Actinobacteria	EG	gluconate transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03078	1121296.JONJ01000003_gene756	0.0	1028.0	COG0145@1|root,COG0145@2|Bacteria,1TQVB@1239|Firmicutes,24AJ7@186801|Clostridia,21YSM@1506553|Lachnoclostridium	186801|Clostridia	EQ	Hydantoinase/oxoprolinase N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
PNCOCPKN_03079	997346.HMPREF9374_0063	2.49e-18	89.4	2AG0K@1|root,3164N@2|Bacteria,1V7CN@1239|Firmicutes,4HSP9@91061|Bacilli,27C2K@186824|Thermoactinomycetaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03080	1121296.JONJ01000003_gene758	2.72e-221	621.0	COG0644@1|root,COG0644@2|Bacteria,1TR0D@1239|Firmicutes,24BE3@186801|Clostridia,21ZUQ@1506553|Lachnoclostridium	186801|Clostridia	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
PNCOCPKN_03081	877421.AUJT01000002_gene1169	9.73e-108	321.0	COG1737@1|root,COG1737@2|Bacteria,1TR5E@1239|Firmicutes,247Z7@186801|Clostridia,27K6U@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
PNCOCPKN_03082	592026.GCWU0000282_000636	5.19e-124	365.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia	186801|Clostridia	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
PNCOCPKN_03083	585394.RHOM_09110	0.0	1038.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia	186801|Clostridia	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
PNCOCPKN_03084	411489.CLOL250_01411	8.72e-64	204.0	2EX79@1|root,33QI5@2|Bacteria,1VS8K@1239|Firmicutes,24YCQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03085	742765.HMPREF9457_01596	0.0	883.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,248DZ@186801|Clostridia,27WC8@189330|Dorea	186801|Clostridia	T	5TM C-terminal transporter carbon starvation CstA	cstA	-	-	-	-	-	-	-	-	-	-	-	CstA,CstA_5TM
PNCOCPKN_03086	483218.BACPEC_01486	7.1e-182	513.0	28JHK@1|root,2Z9B4@2|Bacteria,1TS7Y@1239|Firmicutes,249S0@186801|Clostridia,26AQK@186813|unclassified Clostridiales	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03087	585394.RHOM_09105	2.63e-125	368.0	COG3854@1|root,COG3854@2|Bacteria,1TQ23@1239|Firmicutes,248S2@186801|Clostridia	186801|Clostridia	S	stage III sporulation protein AA	spoIIIAA	-	-	ko:K06390	-	-	-	-	ko00000	-	-	-	T2SSE
PNCOCPKN_03088	397290.C810_02092	4.22e-10	63.2	29N29@1|root,30900@2|Bacteria,1U486@1239|Firmicutes,24GD0@186801|Clostridia,27PVV@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Stage III sporulation protein AB (spore_III_AB)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_III_AB
PNCOCPKN_03089	585394.RHOM_09095	1.58e-33	115.0	2E555@1|root,32ZY3@2|Bacteria,1VEM4@1239|Firmicutes,24QNR@186801|Clostridia	186801|Clostridia	S	Stage III sporulation protein AC	spoIIIAC	-	-	ko:K06392	-	-	-	-	ko00000	-	-	-	SpoIIIAC
PNCOCPKN_03090	585394.RHOM_09090	1.75e-45	150.0	2CPUI@1|root,32SJW@2|Bacteria,1VA9Y@1239|Firmicutes,24NK6@186801|Clostridia	186801|Clostridia	S	Stage III sporulation protein AD	spoIIIAD	-	-	ko:K06393	-	-	-	-	ko00000	-	-	-	SpoIIIAC
PNCOCPKN_03091	622312.ROSEINA2194_01224	1.38e-123	369.0	2C2CG@1|root,2Z7PW@2|Bacteria,1TQQ2@1239|Firmicutes,24AH2@186801|Clostridia	186801|Clostridia	S	stage III sporulation protein AE	spoIIIAE	-	-	ko:K06394	-	-	-	-	ko00000	-	-	-	Spore_III_AE
PNCOCPKN_03093	622312.ROSEINA2194_01222	3.35e-52	173.0	2E6BB@1|root,330Z5@2|Bacteria,1VF3M@1239|Firmicutes,24RAX@186801|Clostridia	186801|Clostridia	S	Stage III sporulation protein AG	spoIIIAG	-	-	ko:K06396	-	-	-	-	ko00000	-	-	-	-
PNCOCPKN_03094	622312.ROSEINA2194_01221	5.61e-95	287.0	28ZIG@1|root,2ZM9W@2|Bacteria,1V2JN@1239|Firmicutes,25BHX@186801|Clostridia	186801|Clostridia	S	SpoIIIAH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIIAH
PNCOCPKN_03095	585394.RHOM_08965	3.79e-255	702.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
PNCOCPKN_03096	585394.RHOM_08960	0.0	1030.0	COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,247X3@186801|Clostridia	186801|Clostridia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
PNCOCPKN_03097	585394.RHOM_08955	6.1e-53	169.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
PNCOCPKN_03099	622312.ROSEINA2194_01218	2.53e-217	605.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
PNCOCPKN_03100	622312.ROSEINA2194_01217	1.55e-76	235.0	COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,24J7X@186801|Clostridia	186801|Clostridia	S	Regulatory protein RecX	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
PNCOCPKN_03101	622312.ROSEINA2194_01216	4.61e-289	799.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia	186801|Clostridia	M	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
PNCOCPKN_03103	585394.RHOM_13875	5.06e-125	362.0	COG0745@1|root,COG0745@2|Bacteria,1UDAQ@1239|Firmicutes,249RQ@186801|Clostridia	186801|Clostridia	KT	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	kdpE_1	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
PNCOCPKN_03105	585394.RHOM_08930	5.56e-110	318.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia	186801|Clostridia	L	Hydrolase, nudix family	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05505	NUDIX
PNCOCPKN_03107	585394.RHOM_08920	6.22e-148	423.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
PNCOCPKN_03108	585394.RHOM_08915	4.64e-232	640.0	COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes,24842@186801|Clostridia	186801|Clostridia	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroH	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS07240	DAHP_synth_1
PNCOCPKN_03109	622312.ROSEINA2194_02777	3.85e-101	301.0	COG0710@1|root,COG0710@2|Bacteria,1TSPN@1239|Firmicutes,249EX@186801|Clostridia	186801|Clostridia	E	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,SKI
PNCOCPKN_03110	622312.ROSEINA2194_02776	8.95e-34	123.0	COG1846@1|root,COG1846@2|Bacteria,1VGEP@1239|Firmicutes,24QRJ@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR
PNCOCPKN_03111	585394.RHOM_08900	0.0	1136.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia	186801|Clostridia	V	Abc transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PNCOCPKN_03112	622312.ROSEINA2194_02774	0.0	1030.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PNCOCPKN_03113	622312.ROSEINA2194_02772	1.97e-194	543.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia	186801|Clostridia	C	Belongs to the LDH MDH superfamily. LDH family	-	-	-	-	-	-	-	-	-	-	-	-	Ldh_1_C,Ldh_1_N
PNCOCPKN_03114	585394.RHOM_08885	8.55e-163	468.0	COG1442@1|root,COG1442@2|Bacteria,1U86V@1239|Firmicutes,24CPG@186801|Clostridia	186801|Clostridia	M	Domain of unknown function (DUF4422)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4422
PNCOCPKN_03116	585394.RHOM_08880	1.42e-135	404.0	COG3103@1|root,COG3103@2|Bacteria,COG4991@2|Bacteria,1USNV@1239|Firmicutes,24DRI@186801|Clostridia	186801|Clostridia	T	Bacterial SH3 domain homologues	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
PNCOCPKN_03117	622312.ROSEINA2194_02768	1.98e-141	404.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluF	-	5.4.99.21,5.4.99.22	ko:K06178,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
PNCOCPKN_03118	585394.RHOM_08870	0.0	1100.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
PNCOCPKN_03119	622312.ROSEINA2194_02766	1.14e-204	568.0	COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,247NP@186801|Clostridia	186801|Clostridia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS11970	HTS
PNCOCPKN_03121	318464.IO99_03650	1.68e-61	197.0	COG3177@1|root,COG3177@2|Bacteria,1TZWX@1239|Firmicutes,247MZ@186801|Clostridia,36FX9@31979|Clostridiaceae	186801|Clostridia	K	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
PNCOCPKN_03122	585394.RHOM_08855	2.52e-76	228.0	COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,24JNM@186801|Clostridia	186801|Clostridia	S	protein conserved in bacteria	asp	-	-	-	-	-	-	-	-	-	-	-	Asp23
PNCOCPKN_03123	622312.ROSEINA2194_02748	2.31e-44	147.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
PNCOCPKN_03124	622312.ROSEINA2194_02747	5.74e-202	569.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,247KE@186801|Clostridia	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
PNCOCPKN_03125	622312.ROSEINA2194_02746	1.32e-20	84.0	COG1722@1|root,COG1722@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease VII activity	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
PNCOCPKN_03126	585394.RHOM_08835	2.13e-161	457.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,248DE@186801|Clostridia	186801|Clostridia	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iHN637.CLJU_RS05465	polyprenyl_synt
PNCOCPKN_03127	585394.RHOM_08830	0.0	1061.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
PNCOCPKN_03128	622312.ROSEINA2194_02743	2.61e-155	440.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,247VH@186801|Clostridia	186801|Clostridia	J	Ribosomal RNA large subunit methyltransferase J	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
PNCOCPKN_03129	622312.ROSEINA2194_02742	4.85e-138	398.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia	186801|Clostridia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
PNCOCPKN_03130	622312.ROSEINA2194_02741	1.05e-80	241.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
PNCOCPKN_03131	585394.RHOM_08810	2.4e-231	656.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,247KB@186801|Clostridia	186801|Clostridia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
PNCOCPKN_03132	585394.RHOM_08805	7.11e-163	470.0	COG3480@1|root,COG3480@2|Bacteria,1UI0S@1239|Firmicutes,25E9E@186801|Clostridia	186801|Clostridia	T	Stage IV sporulation protein B	spoIVB	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S55
PNCOCPKN_03133	585394.RHOM_08800	1.86e-154	456.0	COG0457@1|root,COG2199@1|root,COG0457@2|Bacteria,COG3706@2|Bacteria,1TS77@1239|Firmicutes,24E4N@186801|Clostridia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,TPR_8
PNCOCPKN_03134	585394.RHOM_08795	3.17e-154	437.0	COG2201@1|root,COG2201@2|Bacteria,1VQS3@1239|Firmicutes,25E3X@186801|Clostridia	186801|Clostridia	NT	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process	spo0A	-	-	ko:K03413,ko:K07699	ko02020,ko02024,ko02030,map02020,map02024,map02030	M00485,M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg,Spo0A_C
PNCOCPKN_03135	622312.ROSEINA2194_02735	2.08e-285	788.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	-	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
PNCOCPKN_03136	585394.RHOM_08680	7.96e-110	328.0	28PM6@1|root,2ZCAA@2|Bacteria,1V4NT@1239|Firmicutes,24HIP@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03137	585394.RHOM_08675	7.82e-181	511.0	COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia	186801|Clostridia	P	ABC transporter, solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
PNCOCPKN_03138	622312.ROSEINA2194_02731	1.36e-136	392.0	COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,25E3C@186801|Clostridia	186801|Clostridia	P	Abc transporter, permease protein	potC	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
PNCOCPKN_03139	622312.ROSEINA2194_02730	8.71e-159	449.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,247Y8@186801|Clostridia	186801|Clostridia	P	ABC transporter, permease protein	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
PNCOCPKN_03140	622312.ROSEINA2194_02729	1.37e-231	640.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
PNCOCPKN_03141	1235790.C805_01284	7.35e-95	280.0	COG1396@1|root,COG1396@2|Bacteria,1V1K5@1239|Firmicutes,24FTC@186801|Clostridia,25WE3@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	puuR	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3
PNCOCPKN_03143	585394.RHOM_08625	2.55e-123	354.0	COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,24850@186801|Clostridia	186801|Clostridia	F	Cytidine monophosphokinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
PNCOCPKN_03144	585394.RHOM_08620	3.27e-201	566.0	COG2755@1|root,COG2755@2|Bacteria,1UYZ1@1239|Firmicutes,24BMN@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1,Lipase_GDSL_2
PNCOCPKN_03146	1121115.AXVN01000012_gene3091	7.27e-15	68.9	COG2104@1|root,COG2104@2|Bacteria,1VKB4@1239|Firmicutes,25HV0@186801|Clostridia,3Y0TI@572511|Blautia	186801|Clostridia	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
PNCOCPKN_03147	537007.BLAHAN_06473	8.97e-150	425.0	COG2022@1|root,COG2022@2|Bacteria,1TQZ1@1239|Firmicutes,247TJ@186801|Clostridia,3XZG0@572511|Blautia	186801|Clostridia	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
PNCOCPKN_03148	1280698.AUJS01000004_gene2938	3.24e-238	661.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia,27URQ@189330|Dorea	186801|Clostridia	C	Biotin and Thiamin Synthesis associated domain	thiH	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
PNCOCPKN_03149	411459.RUMOBE_00194	1.68e-68	215.0	COG0352@1|root,COG0352@2|Bacteria,1V4SE@1239|Firmicutes,24JTR@186801|Clostridia,3Y00P@572511|Blautia	186801|Clostridia	H	Thiamine monophosphate synthase	tenI	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06600	TMP-TENI
PNCOCPKN_03150	622312.ROSEINA2194_02259	1.67e-80	249.0	COG0850@1|root,COG0850@2|Bacteria,1VAPC@1239|Firmicutes,24MV1@186801|Clostridia	186801|Clostridia	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C
PNCOCPKN_03151	622312.ROSEINA2194_02260	2.91e-158	447.0	COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,249BB@186801|Clostridia	186801|Clostridia	D	Belongs to the ParA family	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
PNCOCPKN_03152	658086.HMPREF0994_01119	3.93e-46	149.0	COG0851@1|root,COG0851@2|Bacteria,1VFST@1239|Firmicutes,24QT6@186801|Clostridia,27NQT@186928|unclassified Lachnospiraceae	186801|Clostridia	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
PNCOCPKN_03153	411463.EUBVEN_02080	2.3e-195	551.0	COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,248AY@186801|Clostridia,25UZ8@186806|Eubacteriaceae	186801|Clostridia	E	Aminotransferase, class I	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
PNCOCPKN_03154	411463.EUBVEN_02011	3.87e-160	451.0	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,24849@186801|Clostridia,25V2W@186806|Eubacteriaceae	186801|Clostridia	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
PNCOCPKN_03156	622312.ROSEINA2194_02797	9.09e-124	382.0	COG2871@1|root,COG3894@1|root,COG2871@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia	186801|Clostridia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
PNCOCPKN_03157	1226325.HMPREF1548_00183	1.33e-257	717.0	COG4209@1|root,COG4209@2|Bacteria,1TSTC@1239|Firmicutes,24AFM@186801|Clostridia,36FY9@31979|Clostridiaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
PNCOCPKN_03158	1226325.HMPREF1548_00184	3.1e-203	565.0	COG0395@1|root,COG0395@2|Bacteria,1TRB1@1239|Firmicutes,2488P@186801|Clostridia,36F12@31979|Clostridiaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
PNCOCPKN_03159	658086.HMPREF0994_06596	0.0	951.0	COG1653@1|root,COG1653@2|Bacteria,1TPHG@1239|Firmicutes,24AFQ@186801|Clostridia,27J6A@186928|unclassified Lachnospiraceae	186801|Clostridia	G	ABC transporter substrate-binding protein	-	-	-	ko:K02027,ko:K17318	ko02010,map02010	M00207,M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.29,3.A.1.1.9	-	-	-
PNCOCPKN_03160	1469948.JPNB01000002_gene2805	8.35e-68	213.0	COG5578@1|root,COG5578@2|Bacteria,1VJNV@1239|Firmicutes,24SDJ@186801|Clostridia	186801|Clostridia	S	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
PNCOCPKN_03161	1469948.JPNB01000002_gene2802	0.0	1006.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,36FQ1@31979|Clostridiaceae	186801|Clostridia	G	beta-galactosidase	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
PNCOCPKN_03162	1410622.JNKY01000019_gene1711	1.34e-244	684.0	COG3669@1|root,COG3669@2|Bacteria,1TT4V@1239|Firmicutes,24A0S@186801|Clostridia,27IVN@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
PNCOCPKN_03163	573061.Clocel_0036	8.6e-122	379.0	COG2972@1|root,COG2972@2|Bacteria,1UY73@1239|Firmicutes,24AX8@186801|Clostridia,36G3Y@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase,dCache_1
PNCOCPKN_03164	1280685.AUKC01000023_gene851	1.23e-184	537.0	COG1653@1|root,COG1653@2|Bacteria,1TQ1D@1239|Firmicutes,24AFW@186801|Clostridia,4BXI8@830|Butyrivibrio	186801|Clostridia	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
PNCOCPKN_03165	1280390.CBQR020000094_gene2073	4.1e-255	713.0	COG1492@1|root,COG1492@2|Bacteria,1TP5E@1239|Firmicutes,4HAQW@91061|Bacilli,26UJH@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,CbiA,GATase_3
PNCOCPKN_03166	877420.ATVW01000017_gene1701	2.65e-139	408.0	COG2038@1|root,COG2038@2|Bacteria,1TPC1@1239|Firmicutes,25DH5@186801|Clostridia,27IYG@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
PNCOCPKN_03167	1235793.C809_02443	1.16e-49	166.0	COG2087@1|root,COG2087@2|Bacteria,1V6F8@1239|Firmicutes,24JF6@186801|Clostridia,27M8T@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Cobinamide kinase / cobinamide phosphate guanyltransferase	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
PNCOCPKN_03168	1120746.CCNL01000008_gene545	3.67e-105	311.0	COG0368@1|root,COG0368@2|Bacteria	2|Bacteria	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008818,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
PNCOCPKN_03169	537007.BLAHAN_05799	8.85e-29	108.0	COG2087@1|root,COG2087@2|Bacteria,1VG8S@1239|Firmicutes,24QSM@186801|Clostridia,3Y0HX@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	CobU
PNCOCPKN_03170	1120746.CCNL01000008_gene547	3.01e-71	222.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	cobC	-	3.1.3.73,6.3.1.10	ko:K02226,ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R04594,R06529,R07302,R11173	RC00017,RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
PNCOCPKN_03171	622312.ROSEINA2194_01858	1.07e-138	402.0	COG1270@1|root,COG1270@2|Bacteria,1TQ3X@1239|Firmicutes,247PR@186801|Clostridia	186801|Clostridia	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
PNCOCPKN_03172	689781.AUJX01000003_gene2930	3.8e-80	241.0	COG3467@1|root,COG3467@2|Bacteria,1V6NS@1239|Firmicutes,24JA3@186801|Clostridia,2PSHU@265975|Oribacterium	186801|Clostridia	S	Pyridoxamine 5'-phosphate oxidase	nimA	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
PNCOCPKN_03173	622312.ROSEINA2194_02722	1.77e-30	113.0	2EKR7@1|root,33EEZ@2|Bacteria,1VQ0F@1239|Firmicutes,24UDN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03174	585394.RHOM_08610	4.43e-69	214.0	COG2206@1|root,COG2206@2|Bacteria,1UI74@1239|Firmicutes,25EC7@186801|Clostridia	186801|Clostridia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
PNCOCPKN_03175	585394.RHOM_08605	1.31e-158	458.0	COG4641@1|root,COG4641@2|Bacteria,1V642@1239|Firmicutes,24IV8@186801|Clostridia	186801|Clostridia	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
PNCOCPKN_03176	622312.ROSEINA2194_02720	7.62e-128	367.0	COG1636@1|root,COG1636@2|Bacteria,1TT7H@1239|Firmicutes,248EA@186801|Clostridia	186801|Clostridia	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
PNCOCPKN_03177	585394.RHOM_08595	2.25e-305	836.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,2489H@186801|Clostridia	186801|Clostridia	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
PNCOCPKN_03178	585394.RHOM_08590	2.31e-258	708.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,248ZR@186801|Clostridia	186801|Clostridia	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
PNCOCPKN_03179	585394.RHOM_08585	4.27e-233	652.0	COG1672@1|root,COG1672@2|Bacteria,1TR21@1239|Firmicutes,24ADD@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
PNCOCPKN_03180	585394.RHOM_08580	0.0	2016.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	traI	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
PNCOCPKN_03181	622312.ROSEINA2194_01352	5.04e-146	413.0	COG1207@1|root,COG1207@2|Bacteria	2|Bacteria	M	glucosamine-1-phosphate N-acetyltransferase activity	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
PNCOCPKN_03182	622312.ROSEINA2194_01774	1.73e-151	448.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,25BET@186801|Clostridia	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
PNCOCPKN_03183	585394.RHOM_08565	3.45e-115	355.0	COG1033@1|root,COG1033@2|Bacteria,1VIN4@1239|Firmicutes	1239|Firmicutes	S	YARHG	-	-	-	-	-	-	-	-	-	-	-	-	YARHG
PNCOCPKN_03184	585394.RHOM_08560	1.39e-165	462.0	COG0822@1|root,COG0822@2|Bacteria,1TQEQ@1239|Firmicutes,248ID@186801|Clostridia	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	NifU_N
PNCOCPKN_03185	622312.ROSEINA2194_01354	3.33e-242	665.0	2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	GGGtGRT
PNCOCPKN_03186	622312.ROSEINA2194_04170	5.78e-276	766.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,248FH@186801|Clostridia	186801|Clostridia	L	ImpB MucB SamB family protein	-	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
PNCOCPKN_03187	1226322.HMPREF1545_00232	1.46e-43	147.0	2DMPJ@1|root,32SWG@2|Bacteria,1V7RA@1239|Firmicutes,24NGU@186801|Clostridia,2N7F0@216572|Oscillospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03188	585394.RHOM_08090	3.7e-273	778.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,2493H@186801|Clostridia	186801|Clostridia	S	YhgE Pip	pip1	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	ABC2_membrane,ABC2_membrane_3,DUF3533
PNCOCPKN_03189	585394.RHOM_08085	1.44e-46	156.0	COG1511@1|root,COG1511@2|Bacteria,1VFYY@1239|Firmicutes,24RU2@186801|Clostridia	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03190	585394.RHOM_08080	2.28e-288	813.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,2493H@186801|Clostridia	186801|Clostridia	S	YhgE Pip	pip1	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	ABC2_membrane,ABC2_membrane_3,DUF3533
PNCOCPKN_03192	585394.RHOM_08065	2.56e-104	303.0	COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,24HZM@186801|Clostridia	186801|Clostridia	E	Acetolactate synthase, small subunit	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10025	ACT,ACT_5,ALS_ss_C
PNCOCPKN_03193	622312.ROSEINA2194_01363	1.42e-245	674.0	COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia	186801|Clostridia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
PNCOCPKN_03194	585394.RHOM_08055	0.0	1599.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
PNCOCPKN_03195	585394.RHOM_08050	3.2e-267	738.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PNCOCPKN_03196	585394.RHOM_08035	2.92e-184	515.0	COG0583@1|root,COG0583@2|Bacteria,1TR84@1239|Firmicutes,24BU7@186801|Clostridia	186801|Clostridia	K	lysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PNCOCPKN_03197	585394.RHOM_08030	4.47e-294	803.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01703,ko:K20452	ko00290,ko00660,ko00760,ko00966,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map00966,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04465	Aconitase
PNCOCPKN_03198	622312.ROSEINA2194_03857	8.27e-111	318.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01704,ko:K20453	ko00290,ko00660,ko00760,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R10170	RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
PNCOCPKN_03199	1469948.JPNB01000002_gene2888	8.7e-129	374.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1TQ2W@1239|Firmicutes,24A5W@186801|Clostridia,36VIU@31979|Clostridiaceae	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
PNCOCPKN_03200	397287.C807_03129	0.0	1235.0	COG5426@1|root,COG5426@2|Bacteria,1TPH0@1239|Firmicutes,24892@186801|Clostridia,27J14@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Lacto-N-biose phosphorylase C-terminal domain	-	-	2.4.1.211	ko:K15533	-	-	-	-	ko00000,ko01000	-	-	-	LBP_C,LBP_M,Lact_bio_phlase
PNCOCPKN_03201	585394.RHOM_04095	2.07e-242	676.0	COG1653@1|root,COG1653@2|Bacteria,1TQ0V@1239|Firmicutes,2481M@186801|Clostridia	186801|Clostridia	G	solute-binding protein	-	-	-	ko:K10188	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	SBP_bac_1,SBP_bac_8
PNCOCPKN_03202	585394.RHOM_04100	4.18e-171	482.0	COG1175@1|root,COG1175@2|Bacteria,1TPMR@1239|Firmicutes,2494U@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K10189	ko02010,map02010	M00199,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.4	-	-	BPD_transp_1
PNCOCPKN_03203	585394.RHOM_04105	1.11e-158	448.0	COG0395@1|root,COG0395@2|Bacteria,1TSGI@1239|Firmicutes,24BDH@186801|Clostridia	186801|Clostridia	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10190	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	BPD_transp_1
PNCOCPKN_03205	585394.RHOM_04115	2.77e-238	663.0	COG5434@1|root,COG5434@2|Bacteria,1TRWY@1239|Firmicutes,24DY3@186801|Clostridia	186801|Clostridia	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03206	585394.RHOM_08330	1.61e-174	495.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
PNCOCPKN_03207	585394.RHOM_08325	5.11e-183	511.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,2486P@186801|Clostridia	186801|Clostridia	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
PNCOCPKN_03208	585394.RHOM_08320	1.5e-31	111.0	COG4224@1|root,COG4224@2|Bacteria,1TUAX@1239|Firmicutes,24QS9@186801|Clostridia	186801|Clostridia	S	UPF0291 protein	ynzC	-	-	-	-	-	-	-	-	-	-	-	DUF896
PNCOCPKN_03209	622312.ROSEINA2194_00521	2e-47	160.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,24N7H@186801|Clostridia	186801|Clostridia	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	fthC	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
PNCOCPKN_03210	585394.RHOM_08310	5.02e-238	662.0	COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,248NX@186801|Clostridia	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
PNCOCPKN_03211	585394.RHOM_08305	1e-16	79.7	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
PNCOCPKN_03212	497965.Cyan7822_5205	1.3e-81	271.0	COG4637@1|root,COG4938@1|root,COG4637@2|Bacteria,COG4938@2|Bacteria,1G2C3@1117|Cyanobacteria,3KIZT@43988|Cyanothece	1117|Cyanobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,DUF3696
PNCOCPKN_03214	1235793.C809_02624	0.0	897.0	COG1961@1|root,COG1961@2|Bacteria,1TS5B@1239|Firmicutes,248MZ@186801|Clostridia,27KAN@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
PNCOCPKN_03215	1280698.AUJS01000007_gene1002	7.22e-19	85.9	COG1396@1|root,COG1396@2|Bacteria,1VEU8@1239|Firmicutes,24QN0@186801|Clostridia,27VXX@189330|Dorea	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
PNCOCPKN_03216	585394.RHOM_11965	1.23e-20	87.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
PNCOCPKN_03217	525254.HMPREF0072_0267	4.91e-33	118.0	COG1396@1|root,COG1396@2|Bacteria,1VEU8@1239|Firmicutes,24QN0@186801|Clostridia	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
PNCOCPKN_03218	97139.C824_00757	1.33e-33	123.0	COG1396@1|root,COG1396@2|Bacteria,1VEU8@1239|Firmicutes,24QN0@186801|Clostridia,36NJZ@31979|Clostridiaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
PNCOCPKN_03222	1410674.JNKU01000023_gene2053	5.36e-39	139.0	2EBJH@1|root,335JZ@2|Bacteria,1VG00@1239|Firmicutes,4HQFE@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03227	1121946.AUAX01000008_gene7252	0.000247	47.4	COG1396@1|root,COG1396@2|Bacteria,2GXAS@201174|Actinobacteria,4DDF3@85008|Micromonosporales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
PNCOCPKN_03228	411490.ANACAC_02383	1.49e-75	243.0	COG0358@1|root,COG0358@2|Bacteria,1TQTJ@1239|Firmicutes,25C9F@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3991,Toprim_2
PNCOCPKN_03229	1506994.JNLQ01000001_gene362	6.95e-51	174.0	COG1192@1|root,COG1192@2|Bacteria,1V64B@1239|Firmicutes,25CDB@186801|Clostridia,4BWPU@830|Butyrivibrio	186801|Clostridia	D	ATPase MipZ	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
PNCOCPKN_03230	1410624.JNKK01000001_gene603	1.21e-59	201.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia,27J9V@186928|unclassified Lachnospiraceae	186801|Clostridia	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
PNCOCPKN_03232	411902.CLOBOL_05744	2.09e-44	160.0	2F0H7@1|root,340C6@2|Bacteria,1VXA4@1239|Firmicutes,251HD@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03234	1235790.C805_01047	2.59e-61	195.0	COG2003@1|root,COG2003@2|Bacteria,1V38E@1239|Firmicutes,24M00@186801|Clostridia,25WF6@186806|Eubacteriaceae	186801|Clostridia	L	RadC-like JAB domain	-	-	-	-	-	-	-	-	-	-	-	-	RadC
PNCOCPKN_03235	457412.RSAG_01929	4.34e-84	263.0	COG5464@1|root,COG5464@2|Bacteria,1TUFY@1239|Firmicutes,259KT@186801|Clostridia,3WQBQ@541000|Ruminococcaceae	186801|Clostridia	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03236	1442598.JABW01000024_gene1558	2.68e-05	47.8	2AJ3T@1|root,319N6@2|Bacteria,1Q3AM@1224|Proteobacteria,42X0U@68525|delta/epsilon subdivisions,2YQZD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
PNCOCPKN_03238	1410631.JHWZ01000002_gene1291	6.07e-49	183.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,248VT@186801|Clostridia,27T7Y@186928|unclassified Lachnospiraceae	186801|Clostridia	U	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
PNCOCPKN_03240	411463.EUBVEN_00579	2.1e-19	97.8	2CF7U@1|root,2Z7U3@2|Bacteria,1UYHD@1239|Firmicutes,24C76@186801|Clostridia,25UXR@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF3801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3801
PNCOCPKN_03242	397288.C806_04831	2e-173	520.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia,27IXT@186928|unclassified Lachnospiraceae	186801|Clostridia	U	Type IV secretory system Conjugative DNA transfer	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf,TraG-D_C
PNCOCPKN_03244	411463.EUBVEN_01667	1.18e-52	180.0	2DB6V@1|root,2Z7IJ@2|Bacteria,1TRNS@1239|Firmicutes,24ANE@186801|Clostridia,25VZH@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03245	411463.EUBVEN_01664	6.47e-06	50.8	28XQJ@1|root,2ZJM8@2|Bacteria,1V2X9@1239|Firmicutes,24E6S@186801|Clostridia,25WT2@186806|Eubacteriaceae	186801|Clostridia	S	PrgI family protein	-	-	-	-	-	-	-	-	-	-	-	-	PrgI
PNCOCPKN_03247	483218.BACPEC_02582	2.84e-260	749.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,248ND@186801|Clostridia,268HK@186813|unclassified Clostridiales	186801|Clostridia	U	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87
PNCOCPKN_03249	411462.DORLON_01893	4.61e-09	64.7	28PM6@1|root,2ZCAA@2|Bacteria,1V4NT@1239|Firmicutes,24HIP@186801|Clostridia,27VG3@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03252	585394.RHOM_05225	7.06e-182	514.0	COG0630@1|root,COG0630@2|Bacteria,1UHT2@1239|Firmicutes,25EN1@186801|Clostridia	186801|Clostridia	NU	COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
PNCOCPKN_03253	585394.RHOM_05230	2.1e-148	442.0	28I5Y@1|root,2Z892@2|Bacteria,1UYUF@1239|Firmicutes,24CM9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03254	585394.RHOM_05235	5.87e-14	69.7	2EG0W@1|root,339SX@2|Bacteria,1VKDR@1239|Firmicutes,24S7Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03257	411489.CLOL250_00770	1.38e-14	85.5	COG5492@1|root,COG5492@2|Bacteria,1VUWB@1239|Firmicutes,24MC1@186801|Clostridia,36VIK@31979|Clostridiaceae	186801|Clostridia	N	COG COG5492 Bacterial surface proteins containing Ig-like domains	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CarboxypepD_reg
PNCOCPKN_03258	1239962.C943_04226	3.71e-75	250.0	COG5635@1|root,COG5635@2|Bacteria,4NIRY@976|Bacteroidetes,47T6P@768503|Cytophagia	976|Bacteroidetes	T	NACHT domain	-	-	-	-	-	-	-	-	-	-	-	-	NACHT
PNCOCPKN_03259	457412.RSAG_00322	3e-137	404.0	COG3012@1|root,COG3012@2|Bacteria,1V9F3@1239|Firmicutes,24MI8@186801|Clostridia	186801|Clostridia	S	SEC-C Motif Domain Protein	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C
PNCOCPKN_03260	1235800.C819_00706	0.0	908.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,248J7@186801|Clostridia,27J3U@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
PNCOCPKN_03261	665950.HMPREF1025_02671	4.8e-53	179.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,24EUS@186801|Clostridia,27KUD@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
PNCOCPKN_03262	585394.RHOM_16355	8.48e-158	444.0	COG3279@1|root,COG3279@2|Bacteria,1V217@1239|Firmicutes,24GJ1@186801|Clostridia	186801|Clostridia	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
PNCOCPKN_03263	622312.ROSEINA2194_04246	0.0	930.0	28RNQ@1|root,2ZE1D@2|Bacteria,1V1HU@1239|Firmicutes,24GGJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03264	622312.ROSEINA2194_02680	1.7e-28	106.0	2AY2J@1|root,31Q4C@2|Bacteria,1V70J@1239|Firmicutes,24JN7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03265	585394.RHOM_16345	3.14e-147	415.0	2DB9G@1|root,2Z7WS@2|Bacteria,1TRCU@1239|Firmicutes,249J8@186801|Clostridia	186801|Clostridia	S	Domain of unknown function, E. rectale Gene description (DUF3879)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3879
PNCOCPKN_03266	585394.RHOM_16350	7.01e-125	365.0	COG3290@1|root,COG3290@2|Bacteria,1V225@1239|Firmicutes,24DB7@186801|Clostridia	186801|Clostridia	T	signal transduction protein with a C-terminal ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
PNCOCPKN_03267	622312.ROSEINA2194_03927	0.0	934.0	COG3501@1|root,COG3501@2|Bacteria,1V3I5@1239|Firmicutes,24GKG@186801|Clostridia	186801|Clostridia	F	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
PNCOCPKN_03269	511680.BUTYVIB_02374	7.97e-69	224.0	COG2865@1|root,COG2865@2|Bacteria,1TQIP@1239|Firmicutes,24CJ9@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4
PNCOCPKN_03270	585394.RHOM_12965	1.99e-69	209.0	2CABA@1|root,32ZBQ@2|Bacteria,1VFWB@1239|Firmicutes,24RY5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03271	585394.RHOM_12960	1.3e-125	358.0	2C4YS@1|root,32RET@2|Bacteria,1V2W0@1239|Firmicutes,24H32@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03273	622312.ROSEINA2194_01681	1.57e-233	644.0	COG3943@1|root,COG3943@2|Bacteria,1TPH4@1239|Firmicutes,248NI@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_RhuM
PNCOCPKN_03274	861454.HMPREF9099_02905	1.03e-06	48.1	COG3514@1|root,COG3514@2|Bacteria,1VFWT@1239|Firmicutes,24S45@186801|Clostridia,27PNA@186928|unclassified Lachnospiraceae	186801|Clostridia	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
PNCOCPKN_03276	585394.RHOM_05265	1.91e-92	323.0	2C4YK@1|root,342PE@2|Bacteria,1VWY9@1239|Firmicutes,24TZZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03277	1280664.AUIX01000050_gene3552	3.05e-226	631.0	COG1819@1|root,COG1819@2|Bacteria,1V1WQ@1239|Firmicutes,24NIJ@186801|Clostridia,4BYGC@830|Butyrivibrio	186801|Clostridia	CG	Glycosyltransferase family 28 N-terminal domain	-	-	2.4.1.173	ko:K05841	-	-	-	-	ko00000,ko01000,ko01003	-	GT1	-	Glyco_transf_28,UDPGT
PNCOCPKN_03278	97139.C824_04337	3.4e-22	87.8	2DNMA@1|root,32Y3J@2|Bacteria,1VJCJ@1239|Firmicutes,24RI7@186801|Clostridia,36Q0E@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03279	411470.RUMGNA_01472	4.96e-185	518.0	COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,24DGQ@186801|Clostridia,3Y2AQ@572511|Blautia	186801|Clostridia	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
PNCOCPKN_03280	471875.RUMLAC_02176	5.66e-63	192.0	COG2963@1|root,COG2963@2|Bacteria,1VCC9@1239|Firmicutes,24PD0@186801|Clostridia	186801|Clostridia	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
PNCOCPKN_03281	511680.BUTYVIB_01643	7.38e-98	285.0	COG1671@1|root,COG1671@2|Bacteria,1V9Z0@1239|Firmicutes,24HPW@186801|Clostridia	186801|Clostridia	O	Belongs to the UPF0178 family	-	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
PNCOCPKN_03282	471875.RUMLAC_02136	1.48e-52	168.0	COG0346@1|root,COG0346@2|Bacteria,1V4DI@1239|Firmicutes,24I5W@186801|Clostridia,3WS7K@541000|Ruminococcaceae	186801|Clostridia	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_2
PNCOCPKN_03283	411489.CLOL250_01520	1.02e-76	229.0	2DMJC@1|root,32RYJ@2|Bacteria,1V4GQ@1239|Firmicutes,24IY2@186801|Clostridia	186801|Clostridia	S	COG NOG13916 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF4186
PNCOCPKN_03284	515620.EUBELI_20144	1.89e-87	257.0	COG5015@1|root,COG5015@2|Bacteria,1V43Y@1239|Firmicutes,24HQB@186801|Clostridia,25WPW@186806|Eubacteriaceae	186801|Clostridia	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
PNCOCPKN_03285	1034807.FBFL15_0121	1.82e-63	225.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,4NEHR@976|Bacteroidetes,1HYJU@117743|Flavobacteriia,2NUFA@237|Flavobacterium	976|Bacteroidetes	L	TaqI-like C-terminal specificity domain	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,N6_Mtase,TaqI_C
PNCOCPKN_03287	742733.HMPREF9469_02685	7.6e-194	545.0	COG4804@1|root,COG4804@2|Bacteria,1TP7Q@1239|Firmicutes,24A19@186801|Clostridia,21ZRE@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
PNCOCPKN_03288	428127.EUBDOL_00407	0.0	935.0	COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,3VP6N@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	VirE
PNCOCPKN_03289	585394.RHOM_01845	6.56e-40	132.0	2CCGJ@1|root,32RVM@2|Bacteria,1VAEN@1239|Firmicutes,24MRI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03290	428127.EUBDOL_00407	0.0	940.0	COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,3VP6N@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	VirE
PNCOCPKN_03291	411470.RUMGNA_00760	1.09e-38	129.0	2CCGJ@1|root,32RVM@2|Bacteria,1VAEN@1239|Firmicutes,24MRI@186801|Clostridia,3Y0DH@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03292	622312.ROSEINA2194_03929	9.3e-292	796.0	2C9EF@1|root,32RP7@2|Bacteria,1V15W@1239|Firmicutes,24GXC@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF1911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1910,DUF1911
PNCOCPKN_03293	622312.ROSEINA2194_03930	1.78e-85	264.0	COG3039@1|root,COG3039@2|Bacteria,1U377@1239|Firmicutes,24ASA@186801|Clostridia	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF772
PNCOCPKN_03294	622312.ROSEINA2194_03930	2.19e-246	682.0	COG3039@1|root,COG3039@2|Bacteria,1U377@1239|Firmicutes,24ASA@186801|Clostridia	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF772
PNCOCPKN_03295	622312.ROSEINA2194_03931	0.0	1642.0	COG3501@1|root,COG3501@2|Bacteria,1V3I5@1239|Firmicutes,24GKG@186801|Clostridia	186801|Clostridia	F	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
PNCOCPKN_03296	1122921.KB898188_gene5	2.55e-18	85.1	2EE7B@1|root,3381W@2|Bacteria,1VAIC@1239|Firmicutes,4I80S@91061|Bacilli,26YGS@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DUF4280)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4280
PNCOCPKN_03297	622312.ROSEINA2194_03933	1.08e-113	327.0	2E4BD@1|root,32Z71@2|Bacteria,1VFIN@1239|Firmicutes,24NQT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03298	622312.ROSEINA2194_03934	1.15e-89	266.0	2ER0I@1|root,33IK3@2|Bacteria,1UJZR@1239|Firmicutes,24V5I@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03299	622312.ROSEINA2194_03935	1.4e-155	436.0	2EFPB@1|root,339FB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03300	622312.ROSEINA2194_03936	0.0	904.0	COG3501@1|root,COG3501@2|Bacteria,1V043@1239|Firmicutes,248CZ@186801|Clostridia	186801|Clostridia	S	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
PNCOCPKN_03301	622312.ROSEINA2194_03937	1.05e-113	326.0	2EFPB@1|root,32SG8@2|Bacteria,1UPYZ@1239|Firmicutes,25HS3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03302	622312.ROSEINA2194_03938	3.08e-136	389.0	28N3U@1|root,2ZB9G@2|Bacteria,1V09T@1239|Firmicutes,2493C@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03303	622312.ROSEINA2194_03115	0.0	1677.0	COG0443@1|root,COG0443@2|Bacteria,1TT0Z@1239|Firmicutes,24AG5@186801|Clostridia	186801|Clostridia	O	Heat shock 70 kDa protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03304	622312.ROSEINA2194_03114	1.77e-143	407.0	28N97@1|root,2ZBD9@2|Bacteria,1UYY7@1239|Firmicutes,24MD6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03305	622312.ROSEINA2194_03113	4.99e-278	763.0	28ISJ@1|root,2Z8RQ@2|Bacteria,1TRGC@1239|Firmicutes,24CC6@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03306	622312.ROSEINA2194_03112	0.0	889.0	COG0631@1|root,COG0631@2|Bacteria,1TQWN@1239|Firmicutes,247KV@186801|Clostridia	186801|Clostridia	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
PNCOCPKN_03307	622312.ROSEINA2194_03111	2.98e-183	511.0	COG0631@1|root,COG0631@2|Bacteria,1V094@1239|Firmicutes,24N9G@186801|Clostridia	186801|Clostridia	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2,SpoIIE
PNCOCPKN_03308	622312.ROSEINA2194_03110	2.86e-123	350.0	COG1716@1|root,COG1716@2|Bacteria,1UZ57@1239|Firmicutes,24PC6@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
PNCOCPKN_03309	622312.ROSEINA2194_03109	1.62e-118	340.0	COG1716@1|root,COG1716@2|Bacteria,1VFJ4@1239|Firmicutes,24Q0H@186801|Clostridia	186801|Clostridia	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
PNCOCPKN_03310	622312.ROSEINA2194_03108	8.23e-73	221.0	COG0484@1|root,COG0484@2|Bacteria,1VAWE@1239|Firmicutes	1239|Firmicutes	O	Molecular chaperone	dnaJ3	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ
PNCOCPKN_03311	622312.ROSEINA2194_03107	2.04e-85	253.0	2AGPY@1|root,316XK@2|Bacteria,1V241@1239|Firmicutes,24GUS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03312	622312.ROSEINA2194_03106	3.62e-89	262.0	2AGPY@1|root,309PS@2|Bacteria,1V64Q@1239|Firmicutes,24FXN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03313	622312.ROSEINA2194_03105	0.0	1384.0	2C1IS@1|root,2Z86T@2|Bacteria,1TQRA@1239|Firmicutes,247QX@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03314	1235793.C809_04168	1.44e-18	89.0	COG2304@1|root,COG2304@2|Bacteria,1VDD4@1239|Firmicutes,24B6V@186801|Clostridia	186801|Clostridia	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
PNCOCPKN_03315	622312.ROSEINA2194_03103	7.71e-281	772.0	COG2304@1|root,COG2304@2|Bacteria,1VDD4@1239|Firmicutes,24B6V@186801|Clostridia	186801|Clostridia	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
PNCOCPKN_03316	622312.ROSEINA2194_03971	5.1e-90	268.0	COG4512@1|root,COG4512@2|Bacteria	2|Bacteria	KOT	PFAM Accessory gene regulator B	-	-	-	ko:K07813	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	AgrB
PNCOCPKN_03318	622312.ROSEINA2194_03969	1.43e-245	682.0	COG3290@1|root,COG3290@2|Bacteria,1V46S@1239|Firmicutes,24KBY@186801|Clostridia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
PNCOCPKN_03319	622312.ROSEINA2194_03968	9.74e-145	410.0	COG3279@1|root,COG3279@2|Bacteria	2|Bacteria	KT	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
PNCOCPKN_03320	622312.ROSEINA2194_03967	1.74e-46	151.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
PNCOCPKN_03321	1469948.JPNB01000003_gene64	5.52e-94	283.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,247R1@186801|Clostridia,36H17@31979|Clostridiaceae	186801|Clostridia	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
PNCOCPKN_03322	585394.RHOM_05735	8.9e-303	841.0	COG1404@1|root,COG1404@2|Bacteria,1TQK9@1239|Firmicutes,25B1U@186801|Clostridia	186801|Clostridia	O	Belongs to the peptidase S8 family	cspBA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
PNCOCPKN_03323	1469948.JPNB01000001_gene792	1.34e-66	212.0	COG5523@1|root,COG5523@2|Bacteria,1V6FC@1239|Firmicutes,24JPX@186801|Clostridia,36WXQ@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
PNCOCPKN_03324	622312.ROSEINA2194_02849	2.86e-253	731.0	COG2206@1|root,COG2206@2|Bacteria,1V6WM@1239|Firmicutes,24FPG@186801|Clostridia	186801|Clostridia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF,HD,HD_5,HisKA_7TM
PNCOCPKN_03325	622312.ROSEINA2194_03960	0.0	902.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,247YA@186801|Clostridia	186801|Clostridia	E	Asparagine synthase, glutamine-hydrolyzing	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
PNCOCPKN_03326	585394.RHOM_05655	2.89e-78	238.0	COG0671@1|root,COG0671@2|Bacteria,1VB7J@1239|Firmicutes,24JDD@186801|Clostridia	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
PNCOCPKN_03327	585394.RHOM_05650	6.82e-168	486.0	COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,2488U@186801|Clostridia	186801|Clostridia	M	stage II sporulation protein P	spoIIP	-	-	ko:K06385	-	-	-	-	ko00000	-	-	-	SpoIIP
PNCOCPKN_03328	585394.RHOM_05645	2.58e-183	516.0	COG0680@1|root,COG0680@2|Bacteria,1TPFY@1239|Firmicutes,248TE@186801|Clostridia	186801|Clostridia	C	Initiates the rapid degradation of small, acid-soluble proteins during spore germination	gpr	-	3.4.24.78	ko:K06012	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_A25
PNCOCPKN_03329	585394.RHOM_05640	1.11e-41	138.0	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia	186801|Clostridia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
PNCOCPKN_03330	622312.ROSEINA2194_03952	1.19e-187	526.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia	186801|Clostridia	L	DNA polymerase III (delta' subunit)	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
PNCOCPKN_03331	585394.RHOM_05630	3.3e-182	550.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia	186801|Clostridia	M	Competence protein ComEC	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
PNCOCPKN_03332	585394.RHOM_05625	2.47e-162	462.0	COG5401@1|root,COG5401@2|Bacteria,1UXYS@1239|Firmicutes,24EK4@186801|Clostridia	186801|Clostridia	S	Sporulation and spore germination	-	-	-	ko:K06298	-	-	-	-	ko00000	-	-	-	Germane
PNCOCPKN_03333	585394.RHOM_05620	1.29e-273	757.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
PNCOCPKN_03334	585394.RHOM_05615	2.59e-161	452.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PNCOCPKN_03335	622312.ROSEINA2194_03945	5.28e-51	171.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia	186801|Clostridia	L	TIGRFAM Competence protein ComEA, helix-hairpin-helix	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
PNCOCPKN_03336	585394.RHOM_05605	1.06e-142	417.0	COG2182@1|root,COG2182@2|Bacteria,1V0VV@1239|Firmicutes,24E7F@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
PNCOCPKN_03337	585394.RHOM_05600	5.23e-247	682.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia	186801|Clostridia	E	PFAM Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
PNCOCPKN_03338	585394.RHOM_05595	1.95e-195	544.0	COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,2486J@186801|Clostridia	186801|Clostridia	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
PNCOCPKN_03339	622312.ROSEINA2194_03939	4.13e-249	689.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
PNCOCPKN_03340	585394.RHOM_05585	1.94e-86	258.0	COG0454@1|root,COG0456@2|Bacteria,1V4GU@1239|Firmicutes,24IME@186801|Clostridia	186801|Clostridia	K	Acetyltransferase, gnat family	RimI	-	2.3.1.1	ko:K22477	ko00220,ko01210,ko01230,map00220,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
PNCOCPKN_03341	622312.ROSEINA2194_04241	4.55e-243	669.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,247R3@186801|Clostridia	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
PNCOCPKN_03342	585394.RHOM_05575	6.14e-298	812.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia	186801|Clostridia	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
PNCOCPKN_03343	1235800.C819_03155	3.67e-148	430.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,248AH@186801|Clostridia,27MED@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Peptidase dimerisation domain	-	-	-	ko:K01436,ko:K21613	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
PNCOCPKN_03344	1226325.HMPREF1548_00432	3.79e-151	431.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,36E1E@31979|Clostridiaceae	186801|Clostridia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
PNCOCPKN_03345	658086.HMPREF0994_04640	5.81e-189	529.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,27MDB@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
PNCOCPKN_03346	658086.HMPREF0994_04641	7.95e-151	434.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,27JBD@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
PNCOCPKN_03347	658086.HMPREF0994_04642	5.15e-166	471.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,27QSG@186928|unclassified Lachnospiraceae	186801|Clostridia	EP	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
PNCOCPKN_03348	658086.HMPREF0994_04643	1.29e-297	824.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,25CDM@186801|Clostridia,27RMB@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
PNCOCPKN_03349	1226325.HMPREF1548_00426	8.71e-90	269.0	28PR6@1|root,2ZCD4@2|Bacteria,1VRUS@1239|Firmicutes,25DRA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03350	585394.RHOM_05565	1.39e-228	643.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia	186801|Clostridia	K	aminotransferase class I and II	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
PNCOCPKN_03351	585394.RHOM_05560	2.32e-147	421.0	COG1655@1|root,COG1655@2|Bacteria,1V2CM@1239|Firmicutes,25CK4@186801|Clostridia	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2225)	-	-	-	ko:K09766	-	-	-	-	ko00000	-	-	-	DUF2225
PNCOCPKN_03352	622312.ROSEINA2194_03508	0.0	1065.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,247Y0@186801|Clostridia	186801|Clostridia	J	Glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
PNCOCPKN_03353	411474.COPEUT_00843	4.09e-291	798.0	COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,247ZX@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
PNCOCPKN_03354	622312.ROSEINA2194_00134	1.42e-229	635.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
PNCOCPKN_03355	585394.RHOM_09580	2.4e-158	448.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,24838@186801|Clostridia	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
PNCOCPKN_03356	585394.RHOM_09585	2.55e-153	439.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,25C8E@186801|Clostridia	186801|Clostridia	J	Psort location CytoplasmicMembrane, score	prmC	-	-	-	-	-	-	-	-	-	-	-	DUF1385,MTS
PNCOCPKN_03357	622312.ROSEINA2194_00129	1.98e-44	143.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia	186801|Clostridia	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
PNCOCPKN_03358	585394.RHOM_09595	1.06e-261	727.0	COG1158@1|root,COG1158@2|Bacteria,1TPHZ@1239|Firmicutes,247YK@186801|Clostridia	186801|Clostridia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
PNCOCPKN_03359	665950.HMPREF1025_00892	2.89e-123	364.0	COG1396@1|root,COG1396@2|Bacteria,1TQZJ@1239|Firmicutes,25E5Y@186801|Clostridia,27IYF@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PNCOCPKN_03360	67267.JNXT01000092_gene5502	2.15e-15	88.2	COG2304@1|root,COG2304@2|Bacteria,2GKPD@201174|Actinobacteria	201174|Actinobacteria	E	IgA Peptidase M64	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M64
PNCOCPKN_03362	411463.EUBVEN_02876	1.4e-55	176.0	2C5R4@1|root,2ZC1N@2|Bacteria,1V292@1239|Firmicutes,25CQM@186801|Clostridia,25ZT4@186806|Eubacteriaceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
PNCOCPKN_03363	1216362.B437_00875	1.12e-124	361.0	COG0500@1|root,COG2226@2|Bacteria,378H4@32066|Fusobacteria	32066|Fusobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
PNCOCPKN_03364	1336241.JAEB01000004_gene516	2.97e-38	132.0	2AUVQ@1|root,2ZI4I@2|Bacteria,1V1YP@1239|Firmicutes,24FSR@186801|Clostridia,25W7C@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03365	1050201.KB913034_gene1518	3.76e-71	217.0	2AUVQ@1|root,31KJ2@2|Bacteria,1V1UV@1239|Firmicutes,3VRNN@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03366	478749.BRYFOR_09858	1.85e-46	152.0	296XG@1|root,2ZU65@2|Bacteria,1V0MN@1239|Firmicutes,24GI1@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990
PNCOCPKN_03367	1506994.JNLQ01000001_gene263	3.75e-145	415.0	COG2013@1|root,COG2013@2|Bacteria,1TP7N@1239|Firmicutes,249B4@186801|Clostridia,4BZ30@830|Butyrivibrio	186801|Clostridia	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
PNCOCPKN_03368	585394.RHOM_16605	0.0	1348.0	COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,249IG@186801|Clostridia	186801|Clostridia	L	DNA helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,DUF4968,UvrD-helicase,UvrD_C,UvrD_C_2
PNCOCPKN_03369	416870.llmg_1857	5.74e-11	61.2	COG2755@1|root,COG2755@2|Bacteria,1V1CQ@1239|Firmicutes,4HGVZ@91061|Bacilli	91061|Bacilli	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
PNCOCPKN_03370	411462.DORLON_01191	2.85e-116	343.0	COG0583@1|root,COG0583@2|Bacteria,1UXFR@1239|Firmicutes,25C6Q@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	ko:K21755	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
PNCOCPKN_03371	457412.RSAG_01452	1.72e-244	681.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3WGER@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PNCOCPKN_03372	411469.EUBHAL_00026	0.0	979.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia,25UY4@186806|Eubacteriaceae	186801|Clostridia	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
PNCOCPKN_03373	411461.DORFOR_00452	5.51e-286	787.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,27UQI@189330|Dorea	186801|Clostridia	P	COG COG0733 Na -dependent transporters of the SNF family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
PNCOCPKN_03374	585394.RHOM_14880	1.3e-174	498.0	COG0738@1|root,COG0738@2|Bacteria,1TPB5@1239|Firmicutes,24913@186801|Clostridia	186801|Clostridia	G	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PNCOCPKN_03375	1280694.AUJQ01000006_gene775	1.7e-95	307.0	COG2199@1|root,COG2199@2|Bacteria,1V0N3@1239|Firmicutes,24FMU@186801|Clostridia,3NHV9@46205|Pseudobutyrivibrio	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GGDEF,SBP_bac_3
PNCOCPKN_03376	411461.DORFOR_02251	8.94e-182	509.0	COG0826@1|root,COG0826@2|Bacteria,1TRX5@1239|Firmicutes,24CTG@186801|Clostridia,27W8Q@189330|Dorea	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03377	585394.RHOM_10150	0.0	1030.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia	186801|Clostridia	S	Abc transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
PNCOCPKN_03378	411468.CLOSCI_03722	4.4e-184	522.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,249SH@186801|Clostridia,21Y5G@1506553|Lachnoclostridium	186801|Clostridia	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
PNCOCPKN_03379	622312.ROSEINA2194_02760	9.18e-137	395.0	COG0566@1|root,COG0566@2|Bacteria,1TSUW@1239|Firmicutes,24ACK@186801|Clostridia	186801|Clostridia	J	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
PNCOCPKN_03381	1280680.AUJU01000016_gene3966	1.05e-102	317.0	COG0488@1|root,COG0488@2|Bacteria,1TNYS@1239|Firmicutes,248D6@186801|Clostridia,4BYMU@830|Butyrivibrio	186801|Clostridia	S	ATPases associated with a variety of cellular activities	-	-	-	ko:K19350	ko02010,map02010	-	-	-	ko00000,ko00001,ko01504,ko02000	3.A.1.121	-	-	ABC_tran
PNCOCPKN_03382	585394.RHOM_07290	0.0	1188.0	COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,247QW@186801|Clostridia	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PNCOCPKN_03383	622312.ROSEINA2194_03605	2.77e-160	450.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PNCOCPKN_03384	411462.DORLON_02271	7.05e-10	60.5	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia,27W4K@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03385	585394.RHOM_15945	8.02e-106	314.0	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03386	1408306.JHXX01000002_gene3031	4.13e-54	218.0	COG3209@1|root,COG4886@1|root,COG3209@2|Bacteria,COG4886@2|Bacteria,1V44C@1239|Firmicutes,25EA1@186801|Clostridia,4C2BH@830|Butyrivibrio	186801|Clostridia	M	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
PNCOCPKN_03387	411468.CLOSCI_00849	1.51e-22	88.6	COG1396@1|root,COG1396@2|Bacteria,1UHV9@1239|Firmicutes,25E41@186801|Clostridia,223NI@1506553|Lachnoclostridium	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
PNCOCPKN_03388	585394.RHOM_11135	4.36e-45	152.0	2C9RU@1|root,349H4@2|Bacteria,1VYXI@1239|Firmicutes,253A6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03389	397291.C804_05620	1.36e-76	233.0	COG3663@1|root,COG3663@2|Bacteria,1V6GI@1239|Firmicutes,24HD8@186801|Clostridia,27MP7@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
PNCOCPKN_03390	585394.RHOM_11145	1.11e-142	412.0	COG1879@1|root,COG1879@2|Bacteria,1UYPR@1239|Firmicutes,248AW@186801|Clostridia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K17213	ko02010,map02010	M00593	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
PNCOCPKN_03391	397290.C810_01607	1.68e-239	685.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,27IZ3@186928|unclassified Lachnospiraceae	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
PNCOCPKN_03392	585394.RHOM_11155	2.89e-227	627.0	COG2502@1|root,COG2502@2|Bacteria,1TP28@1239|Firmicutes,248S4@186801|Clostridia	186801|Clostridia	E	aspartate--ammonia ligase	asnA	-	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	-	AsnA
PNCOCPKN_03393	585394.RHOM_05395	6.32e-178	499.0	COG0388@1|root,COG0388@2|Bacteria,1TRMU@1239|Firmicutes,25B19@186801|Clostridia	186801|Clostridia	S	N-carbamoylputrescine amidase	aguB	-	3.5.1.53,3.5.1.6	ko:K01431,ko:K12251	ko00240,ko00330,ko00410,ko00770,ko00983,ko01100,map00240,map00330,map00410,map00770,map00983,map01100	M00046	R00905,R01152,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
PNCOCPKN_03394	585394.RHOM_05390	6.79e-179	511.0	COG2957@1|root,COG2957@2|Bacteria,1TQS5@1239|Firmicutes,248CP@186801|Clostridia	186801|Clostridia	E	agmatine deiminase	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
PNCOCPKN_03395	585394.RHOM_05385	1.57e-213	597.0	COG0019@1|root,COG0019@2|Bacteria,1TPQI@1239|Firmicutes,248NH@186801|Clostridia	186801|Clostridia	E	carboxynorspermidine decarboxylase	nspC	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_DAP_Arg_deC
PNCOCPKN_03396	585394.RHOM_05380	3.63e-288	788.0	COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,24AHW@186801|Clostridia	186801|Clostridia	E	Saccharopine dehydrogenase	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
PNCOCPKN_03397	585394.RHOM_05375	1.38e-191	533.0	COG0421@1|root,COG0421@2|Bacteria,1TPG5@1239|Firmicutes,24827@186801|Clostridia	186801|Clostridia	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
PNCOCPKN_03398	585394.RHOM_05370	0.0	873.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia	186801|Clostridia	E	Orn Lys Arg decarboxylase major	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
PNCOCPKN_03399	585394.RHOM_05365	1.4e-160	454.0	COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,2499E@186801|Clostridia	186801|Clostridia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
PNCOCPKN_03400	585394.RHOM_05355	0.0	1150.0	COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,248ZC@186801|Clostridia	186801|Clostridia	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3	fbp	-	3.1.3.11	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_2
PNCOCPKN_03401	585394.RHOM_05350	5.25e-149	423.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia	186801|Clostridia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17035	DapB_C,DapB_N
PNCOCPKN_03402	585394.RHOM_05340	8.91e-179	501.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia	186801|Clostridia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
PNCOCPKN_03403	622312.ROSEINA2194_00317	4.16e-137	389.0	COG0629@1|root,COG0629@2|Bacteria,1TRWZ@1239|Firmicutes,248UD@186801|Clostridia	186801|Clostridia	L	PFAM single-strand binding protein Primosomal replication protein n	ssb1	-	-	-	-	-	-	-	-	-	-	-	SSB
PNCOCPKN_03404	585394.RHOM_05330	0.0	1159.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia	186801|Clostridia	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
PNCOCPKN_03405	585394.RHOM_05325	4.14e-199	574.0	COG2199@1|root,COG2984@1|root,COG2199@2|Bacteria,COG2984@2|Bacteria,1TS5J@1239|Firmicutes,25E4Y@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,GGDEF,PAS_3,PAS_9
PNCOCPKN_03406	585394.RHOM_05320	1.29e-175	498.0	COG0739@1|root,COG0739@2|Bacteria,1TQMQ@1239|Firmicutes,24B3J@186801|Clostridia	186801|Clostridia	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
PNCOCPKN_03407	622312.ROSEINA2194_00337	1.12e-74	225.0	COG0735@1|root,COG0735@2|Bacteria,1V970@1239|Firmicutes,24QK7@186801|Clostridia	186801|Clostridia	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
PNCOCPKN_03408	622312.ROSEINA2194_00338	8.92e-143	410.0	2C6CR@1|root,2Z7X4@2|Bacteria,1UY2Y@1239|Firmicutes,24EJP@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_2
PNCOCPKN_03409	585394.RHOM_04985	2.11e-224	625.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
PNCOCPKN_03410	622312.ROSEINA2194_01132	0.0	1134.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
PNCOCPKN_03411	585394.RHOM_04975	4.32e-76	235.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
PNCOCPKN_03412	585394.RHOM_04970	5.48e-218	606.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,247K2@186801|Clostridia	186801|Clostridia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
PNCOCPKN_03413	1123313.ATUT01000016_gene618	6.95e-37	143.0	COG1835@1|root,COG1835@2|Bacteria,1UXXI@1239|Firmicutes,3VQ6J@526524|Erysipelotrichia	526524|Erysipelotrichia	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
PNCOCPKN_03414	411459.RUMOBE_02728	4.85e-192	583.0	COG4485@1|root,COG4485@2|Bacteria,1TPVY@1239|Firmicutes,24A98@186801|Clostridia,3Y056@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
PNCOCPKN_03416	622312.ROSEINA2194_02532	1.26e-138	416.0	28PI9@1|root,2ZC8C@2|Bacteria,1V36K@1239|Firmicutes,24K4U@186801|Clostridia	186801|Clostridia	S	Glucosyl transferase GtrII	-	-	-	-	-	-	-	-	-	-	-	-	Glucos_trans_II
PNCOCPKN_03417	585394.RHOM_06285	0.0	958.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
PNCOCPKN_03418	585394.RHOM_06280	5.23e-86	263.0	2BFV8@1|root,329QI@2|Bacteria,1V7DP@1239|Firmicutes,24KD4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03419	585394.RHOM_06275	1.48e-124	361.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,249TI@186801|Clostridia	186801|Clostridia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
PNCOCPKN_03421	622312.ROSEINA2194_02810	5.89e-203	563.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,24876@186801|Clostridia	186801|Clostridia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
PNCOCPKN_03422	622312.ROSEINA2194_02811	0.0	1393.0	COG1026@1|root,COG1026@2|Bacteria,1TPD1@1239|Firmicutes	1239|Firmicutes	S	Peptidase M16 inactive domain protein	hypA2	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
PNCOCPKN_03423	585394.RHOM_06255	7.54e-40	132.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia	186801|Clostridia	K	Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
PNCOCPKN_03424	585394.RHOM_06250	5.63e-153	437.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,24CAG@186801|Clostridia	186801|Clostridia	M	mechanosensitive ion channel	mscS	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
PNCOCPKN_03425	585394.RHOM_06245	2.15e-234	652.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia	186801|Clostridia	S	Conserved protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
PNCOCPKN_03426	585394.RHOM_06240	2.37e-254	700.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia	186801|Clostridia	EH	D-isomer specific 2-hydroxyacid dehydrogenase	pdxB	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
PNCOCPKN_03427	585394.RHOM_06235	1.55e-255	701.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia	186801|Clostridia	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
PNCOCPKN_03428	622312.ROSEINA2194_02815	0.0	960.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia	186801|Clostridia	H	Acetolactate synthase, large subunit	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PNCOCPKN_03429	585394.RHOM_06225	0.0	1073.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia	186801|Clostridia	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
PNCOCPKN_03430	622312.ROSEINA2194_02817	3.74e-245	675.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia	186801|Clostridia	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
PNCOCPKN_03432	1211817.CCAT010000044_gene3366	2.24e-106	337.0	COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,248P6@186801|Clostridia,36FST@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
PNCOCPKN_03433	398512.JQKC01000026_gene3782	1.11e-122	372.0	COG0457@1|root,COG0535@1|root,COG0457@2|Bacteria,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,3WHA6@541000|Ruminococcaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
PNCOCPKN_03435	397291.C804_00162	4.71e-44	160.0	COG1396@1|root,COG1396@2|Bacteria,1VC2K@1239|Firmicutes,24NMY@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PNCOCPKN_03436	397291.C804_00163	5.53e-35	136.0	2DY23@1|root,347RM@2|Bacteria,1VQMX@1239|Firmicutes,24UP2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03437	585394.RHOM_06205	5.55e-53	168.0	COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia	186801|Clostridia	U	Preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
PNCOCPKN_03438	585394.RHOM_06200	4.07e-267	732.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia	186801|Clostridia	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
PNCOCPKN_03439	585394.RHOM_06195	6.87e-207	585.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
PNCOCPKN_03440	622312.ROSEINA2194_02823	5.03e-225	624.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
PNCOCPKN_03441	585394.RHOM_05290	1.51e-104	304.0	COG3707@1|root,COG3707@2|Bacteria,1V2S1@1239|Firmicutes,24EWG@186801|Clostridia	186801|Clostridia	K	ANTAR domain protein	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR
PNCOCPKN_03442	585394.RHOM_05285	9.35e-294	805.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia	186801|Clostridia	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
PNCOCPKN_03443	397290.C810_04420	6.1e-135	388.0	COG0106@1|root,COG0106@2|Bacteria,1TPIN@1239|Firmicutes,249HJ@186801|Clostridia,27IKR@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Histidine biosynthesis protein	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
PNCOCPKN_03444	585394.RHOM_05275	0.0	907.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
PNCOCPKN_03445	585394.RHOM_05270	4.9e-226	631.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia	186801|Clostridia	M	Cbs domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
PNCOCPKN_03446	622312.ROSEINA2194_02750	1.18e-43	146.0	2FBHF@1|root,343NR@2|Bacteria,1W0XC@1239|Firmicutes,253BM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03447	1235790.C805_00453	1.68e-52	200.0	COG5279@1|root,COG5279@2|Bacteria	2|Bacteria	D	protein involved in cytokinesis, contains TGc (transglutaminase protease-like) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Flg_new
PNCOCPKN_03448	585394.RHOM_06145	2.57e-143	410.0	COG0726@1|root,COG0726@2|Bacteria,1TT1X@1239|Firmicutes,249PF@186801|Clostridia	186801|Clostridia	G	delta-lactam-biosynthetic de-N-acetylase	pdaA	-	-	ko:K01567	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
PNCOCPKN_03449	585394.RHOM_11010	7.74e-244	678.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PNCOCPKN_03450	585394.RHOM_11015	9.49e-147	415.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PNCOCPKN_03451	585394.RHOM_11020	4.06e-172	499.0	COG0845@1|root,COG0845@2|Bacteria,1V4XJ@1239|Firmicutes,25CIU@186801|Clostridia	186801|Clostridia	M	Efflux transporter, RND family, MFP subunit	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
PNCOCPKN_03452	622312.ROSEINA2194_04095	6.62e-132	382.0	COG2816@1|root,COG2816@2|Bacteria,1TRMF@1239|Firmicutes,24AXA@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	nudC	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
PNCOCPKN_03453	585394.RHOM_06185	1.76e-154	439.0	COG0705@1|root,COG0705@2|Bacteria,1TSBP@1239|Firmicutes,249D8@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
PNCOCPKN_03454	622312.ROSEINA2194_03514	0.0	2590.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia	186801|Clostridia	I	CoA-substrate-specific enzyme activase	hgdC2	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
PNCOCPKN_03458	397288.C806_03858	4.48e-19	82.8	2EG0W@1|root,339SX@2|Bacteria,1VKDR@1239|Firmicutes,24TDP@186801|Clostridia,27QMZ@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03459	585394.RHOM_05230	3.38e-160	472.0	28I5Y@1|root,2Z892@2|Bacteria,1UYUF@1239|Firmicutes,24CM9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03460	585394.RHOM_05225	6.79e-189	532.0	COG0630@1|root,COG0630@2|Bacteria,1UHT2@1239|Firmicutes,25EN1@186801|Clostridia	186801|Clostridia	NU	COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
PNCOCPKN_03463	622312.ROSEINA2194_00296	1.44e-159	452.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,24ADT@186801|Clostridia	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
PNCOCPKN_03464	1123313.ATUT01000032_gene1895	7.03e-33	117.0	COG1917@1|root,COG1917@2|Bacteria,1TRVH@1239|Firmicutes,3VQSY@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Cupin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CMD,Cupin_2
PNCOCPKN_03466	1235790.C805_03449	2.66e-59	184.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,24J8R@186801|Clostridia,25WII@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
PNCOCPKN_03467	1232453.BAIF02000049_gene828	5e-15	70.1	2ENA7@1|root,33FXX@2|Bacteria,1VMBP@1239|Firmicutes,24USY@186801|Clostridia,26CD2@186813|unclassified Clostridiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03468	622312.ROSEINA2194_01496	3.45e-113	344.0	COG0727@1|root,COG0727@2|Bacteria,1UZ5G@1239|Firmicutes,25GD9@186801|Clostridia	186801|Clostridia	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	-
PNCOCPKN_03469	585394.RHOM_06120	0.0	921.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia	186801|Clostridia	S	Abc transporter	yfmM	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
PNCOCPKN_03470	585394.RHOM_06110	1.68e-254	706.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PNCOCPKN_03471	585394.RHOM_06105	4.28e-155	444.0	COG0760@1|root,COG0760@2|Bacteria,1V8DP@1239|Firmicutes,24F9F@186801|Clostridia	186801|Clostridia	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
PNCOCPKN_03472	585394.RHOM_06100	0.0	881.0	COG2509@1|root,COG2509@2|Bacteria,1TP9I@1239|Firmicutes,247QM@186801|Clostridia	186801|Clostridia	S	'oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,HI0933_like,Pyr_redox_2,Thi4
PNCOCPKN_03473	397290.C810_03072	2.71e-37	127.0	2E51P@1|root,32ZV2@2|Bacteria,1VFYG@1239|Firmicutes,24QWN@186801|Clostridia,27P0I@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03474	622312.ROSEINA2194_01555	7.94e-104	305.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
PNCOCPKN_03475	585394.RHOM_06085	0.0	1503.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,248ZF@186801|Clostridia	186801|Clostridia	L	ATP-dependent helicase nuclease subunit A	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
PNCOCPKN_03476	622312.ROSEINA2194_01559	0.0	1480.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia	186801|Clostridia	L	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
PNCOCPKN_03478	713605.ADHG01000006_gene763	3.2e-72	221.0	COG1670@1|root,COG1670@2|Bacteria,1UHY0@1239|Firmicutes,4ISAD@91061|Bacilli,3FBRT@33958|Lactobacillaceae	91061|Bacilli	J	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
PNCOCPKN_03479	1235802.C823_04091	1.59e-158	452.0	COG3755@1|root,COG3755@2|Bacteria,1VHSS@1239|Firmicutes,24U0W@186801|Clostridia	186801|Clostridia	S	Lysozyme inhibitor LprI	-	-	-	-	-	-	-	-	-	-	-	-	LprI
PNCOCPKN_03480	1203606.HMPREF1526_02224	0.0	995.0	COG1961@1|root,COG1961@2|Bacteria,1TS5B@1239|Firmicutes,248MZ@186801|Clostridia,36DMB@31979|Clostridiaceae	186801|Clostridia	L	resolvase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
PNCOCPKN_03481	411483.FAEPRAA2165_00392	3.24e-40	133.0	2CV1B@1|root,334UE@2|Bacteria,1VG8Q@1239|Firmicutes,25D5E@186801|Clostridia,3WKMA@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03482	1203606.HMPREF1526_02222	1.38e-223	616.0	COG1196@1|root,COG1196@2|Bacteria,1TRNI@1239|Firmicutes,247S8@186801|Clostridia,36GMC@31979|Clostridiaceae	186801|Clostridia	D	Plasmid recombination enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
PNCOCPKN_03483	411483.FAEPRAA2165_00394	7.18e-34	120.0	2BZ4K@1|root,33I8K@2|Bacteria,1VQGZ@1239|Firmicutes,24WF9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03484	1203606.HMPREF1526_02220	2.94e-101	292.0	28NID@1|root,2Z9XT@2|Bacteria,1V16A@1239|Firmicutes,24FUK@186801|Clostridia,36KG6@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_VLP
PNCOCPKN_03485	1203606.HMPREF1526_02219	2.14e-57	177.0	2ATT1@1|root,31JBZ@2|Bacteria,1V7KH@1239|Firmicutes,24K1Z@186801|Clostridia,36S9Y@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03486	1203606.HMPREF1526_02218	1.75e-186	518.0	COG1396@1|root,COG1396@2|Bacteria,1TT2N@1239|Firmicutes,2488F@186801|Clostridia,36INQ@31979|Clostridiaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
PNCOCPKN_03487	1203606.HMPREF1526_02217	5.73e-283	774.0	COG0477@1|root,COG0477@2|Bacteria,1UHRM@1239|Firmicutes,24AEF@186801|Clostridia,36UZJ@31979|Clostridiaceae	186801|Clostridia	EGP	Major facilitator superfamily	-	-	-	ko:K08217	-	-	-	-	br01600,ko00000,ko01504,ko02000	2.A.1.21.1,2.A.1.21.22	-	-	MFS_1,MFS_3
PNCOCPKN_03488	622312.ROSEINA2194_02111	3.21e-68	206.0	2DP7G@1|root,330V3@2|Bacteria,1VIP0@1239|Firmicutes,24WEJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03489	1410625.JHWK01000004_gene740	1.91e-39	137.0	COG4804@1|root,COG4804@2|Bacteria,1TP7Q@1239|Firmicutes,249TP@186801|Clostridia,27IFF@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF1016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
PNCOCPKN_03490	622312.ROSEINA2194_01194	1.83e-11	62.4	COG1943@1|root,COG1943@2|Bacteria,1TSQ0@1239|Firmicutes,25CMS@186801|Clostridia	186801|Clostridia	L	PFAM Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
PNCOCPKN_03492	1410612.JNKO01000027_gene270	1.46e-33	119.0	COG1669@1|root,COG1669@2|Bacteria,1V5FK@1239|Firmicutes,25DSQ@186801|Clostridia,2PTZP@265975|Oribacterium	1239|Firmicutes	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
PNCOCPKN_03493	864563.HMPREF9166_1785	3.01e-40	136.0	COG2361@1|root,COG2361@2|Bacteria,1VFEB@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
PNCOCPKN_03494	457421.CBFG_02919	1.33e-20	83.2	COG3311@1|root,COG3311@2|Bacteria,1UID0@1239|Firmicutes,24WMS@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
PNCOCPKN_03495	1196029.ALIM01000001_gene4937	1.52e-43	159.0	COG2369@1|root,COG2369@2|Bacteria,1V7DS@1239|Firmicutes,4HRJV@91061|Bacilli	91061|Bacilli	K	cell adhesion	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03496	272562.CA_C0134	5.76e-17	75.5	2CMHU@1|root,32SEU@2|Bacteria,1VDUI@1239|Firmicutes,251YF@186801|Clostridia,36S51@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03497	622312.ROSEINA2194_03927	1.66e-60	205.0	COG3501@1|root,COG3501@2|Bacteria,1V3I5@1239|Firmicutes,24GKG@186801|Clostridia	186801|Clostridia	F	Rhs element vgr protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
PNCOCPKN_03499	588581.Cpap_3073	7.41e-41	140.0	2BDX4@1|root,327MA@2|Bacteria,1UTHN@1239|Firmicutes,2532C@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03500	1235799.C818_04083	7.25e-11	67.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C,FGE-sulfatase,Glyco_hydro_53
PNCOCPKN_03501	641107.CDLVIII_5646	9.02e-07	57.8	COG3209@1|root,COG5492@1|root,COG3209@2|Bacteria,COG5492@2|Bacteria,1TS8J@1239|Firmicutes,24A7I@186801|Clostridia,36HMP@31979|Clostridiaceae	186801|Clostridia	N	COG COG3291 FOG PKD repeat	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Dockerin_1,LRR_5
PNCOCPKN_03502	1256908.HMPREF0373_00820	7.48e-288	787.0	COG3385@1|root,COG3385@2|Bacteria,1UTR4@1239|Firmicutes,24CFF@186801|Clostridia,25WRV@186806|Eubacteriaceae	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
PNCOCPKN_03503	411473.RUMCAL_00087	2.29e-59	194.0	2C9EF@1|root,32RP7@2|Bacteria,1V15W@1239|Firmicutes,24GXC@186801|Clostridia,3WKK4@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF1910)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1910,DUF1911
PNCOCPKN_03504	1216932.CM240_0224	5.4e-56	198.0	COG1305@1|root,COG1305@2|Bacteria,1UVFG@1239|Firmicutes,2496A@186801|Clostridia	186801|Clostridia	E	Participates in initiation and elongation during chromosome replication	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,Transglut_core
PNCOCPKN_03505	1519439.JPJG01000004_gene1042	4.9e-17	76.6	COG1595@1|root,COG1595@2|Bacteria,1V9ZH@1239|Firmicutes,24HPJ@186801|Clostridia,2N8XY@216572|Oscillospiraceae	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
PNCOCPKN_03506	1519439.JPJG01000004_gene1043	6.6e-63	200.0	28PC7@1|root,2ZC4N@2|Bacteria,1VDMU@1239|Firmicutes,24J12@186801|Clostridia,2N8HS@216572|Oscillospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03507	1196029.ALIM01000001_gene4937	1.52e-43	159.0	COG2369@1|root,COG2369@2|Bacteria,1V7DS@1239|Firmicutes,4HRJV@91061|Bacilli	91061|Bacilli	K	cell adhesion	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03508	272562.CA_C0134	5.76e-17	75.5	2CMHU@1|root,32SEU@2|Bacteria,1VDUI@1239|Firmicutes,251YF@186801|Clostridia,36S51@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03509	411470.RUMGNA_00466	2.67e-115	335.0	COG3335@1|root,COG3335@2|Bacteria,1UZI4@1239|Firmicutes,24BY8@186801|Clostridia,3Y1IU@572511|Blautia	186801|Clostridia	L	COG COG3335 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
PNCOCPKN_03510	411470.RUMGNA_00467	3.34e-73	223.0	COG3415@1|root,COG3415@2|Bacteria,1V3AV@1239|Firmicutes,24G92@186801|Clostridia,3Y26H@572511|Blautia	186801|Clostridia	L	COG COG3335 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,HTH_32
PNCOCPKN_03511	622312.ROSEINA2194_03081	1.62e-128	372.0	COG3290@1|root,COG3290@2|Bacteria,1V225@1239|Firmicutes,24DB7@186801|Clostridia	186801|Clostridia	T	signal transduction protein with a C-terminal ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
PNCOCPKN_03512	585394.RHOM_16345	1.82e-146	413.0	2DB9G@1|root,2Z7WS@2|Bacteria,1TRCU@1239|Firmicutes,249J8@186801|Clostridia	186801|Clostridia	S	Domain of unknown function, E. rectale Gene description (DUF3879)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3879
PNCOCPKN_03513	585394.RHOM_12560	2.3e-124	354.0	28MQP@1|root,2ZAZH@2|Bacteria,1UBV0@1239|Firmicutes,24FBQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03514	622312.ROSEINA2194_01182	6.72e-242	665.0	28KQP@1|root,2ZA8F@2|Bacteria,1UY56@1239|Firmicutes,25DWY@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4885
PNCOCPKN_03515	622312.ROSEINA2194_01181	2.32e-121	350.0	2DQ6A@1|root,334Y3@2|Bacteria,1VJ8J@1239|Firmicutes,24TVF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03517	622312.ROSEINA2194_03345	7.43e-60	196.0	2C0GJ@1|root,2Z7PN@2|Bacteria,1V0HT@1239|Firmicutes,24FCI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03519	483218.BACPEC_00104	3.18e-210	582.0	2BZ87@1|root,2ZAPT@2|Bacteria,1U7MJ@1239|Firmicutes,24B9C@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03520	1256908.HMPREF0373_00348	1.14e-228	629.0	28K66@1|root,2Z9UP@2|Bacteria,1UYD9@1239|Firmicutes,24END@186801|Clostridia,25YVJ@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03521	1256908.HMPREF0373_00347	1.8e-165	464.0	29JMI@1|root,306IV@2|Bacteria,1V3QS@1239|Firmicutes,24HXQ@186801|Clostridia,25XVM@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03522	585394.RHOM_12555	5.98e-126	364.0	290WF@1|root,2ZNI9@2|Bacteria,1V2CA@1239|Firmicutes,24GXX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03523	1256908.HMPREF0373_00354	4.74e-212	586.0	2C3TV@1|root,2Z8B0@2|Bacteria,1V075@1239|Firmicutes,24CC4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03524	1256908.HMPREF0373_00355	4.77e-220	607.0	2DBH1@1|root,2Z96X@2|Bacteria,1UY05@1239|Firmicutes,24ABQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03525	585394.RHOM_12540	1.56e-135	386.0	2DUV5@1|root,33SGF@2|Bacteria,1VSID@1239|Firmicutes,24VUN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03526	511680.BUTYVIB_02361	1.43e-144	409.0	290UV@1|root,2ZNGV@2|Bacteria,1V2HB@1239|Firmicutes,24GF7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03527	515620.EUBELI_20004	2.22e-97	285.0	2E7F0@1|root,331Y0@2|Bacteria,1VEPY@1239|Firmicutes,24TMW@186801|Clostridia,25YNM@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03528	1235793.C809_03823	4.81e-80	248.0	2F0FI@1|root,33TIG@2|Bacteria,1VRUK@1239|Firmicutes,24K3S@186801|Clostridia,27M0B@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03529	397287.C807_03954	5.91e-300	826.0	28RNQ@1|root,2ZE1D@2|Bacteria,1V1HU@1239|Firmicutes,24GGJ@186801|Clostridia,27JX3@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03530	397287.C807_01521	4.04e-30	119.0	28RNQ@1|root,2ZE1D@2|Bacteria,1V1HU@1239|Firmicutes,24GGJ@186801|Clostridia,27K2B@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03531	511680.BUTYVIB_02353	3.79e-232	641.0	28Q3F@1|root,2ZCM3@2|Bacteria,1UPTN@1239|Firmicutes,24GCC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03532	1235793.C809_04492	1.22e-32	117.0	2EQ8C@1|root,30FZS@2|Bacteria,1UEXP@1239|Firmicutes,25JX7@186801|Clostridia,27S10@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03533	742765.HMPREF9457_03287	2.85e-97	289.0	28J9U@1|root,2Z94P@2|Bacteria,1UYN9@1239|Firmicutes,248AD@186801|Clostridia,27WU4@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03534	397291.C804_05752	2.46e-56	177.0	COG1396@1|root,COG1396@2|Bacteria,1TVCG@1239|Firmicutes,25AGD@186801|Clostridia,27QE1@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03535	397291.C804_05753	1.87e-103	306.0	COG3279@1|root,COG3279@2|Bacteria,1V0X7@1239|Firmicutes,24EP3@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
PNCOCPKN_03536	397291.C804_05754	4.34e-159	462.0	COG3290@1|root,COG3290@2|Bacteria,1UZ9P@1239|Firmicutes,24MR7@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
PNCOCPKN_03538	397291.C804_05756	1.99e-71	221.0	COG4512@1|root,COG4512@2|Bacteria,1V8NK@1239|Firmicutes,24KUY@186801|Clostridia,27QCU@186928|unclassified Lachnospiraceae	2|Bacteria	KOT	Accessory gene regulator B	-	-	-	ko:K07813	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	AgrB
PNCOCPKN_03539	622312.ROSEINA2194_01821	1.3e-65	201.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
PNCOCPKN_03540	622312.ROSEINA2194_01819	3.36e-90	264.0	COG1961@1|root,COG1961@2|Bacteria,1VC71@1239|Firmicutes,24QC3@186801|Clostridia	186801|Clostridia	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03541	622312.ROSEINA2194_01818	7.48e-29	103.0	2DC63@1|root,2ZD19@2|Bacteria,1W4M0@1239|Firmicutes,25765@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03542	622312.ROSEINA2194_01817	0.0	1043.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,248J7@186801|Clostridia	186801|Clostridia	L	resolvase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
PNCOCPKN_03543	622312.ROSEINA2194_01816	2.53e-206	571.0	COG1961@1|root,COG1961@2|Bacteria,1UYJM@1239|Firmicutes,24D99@186801|Clostridia	186801|Clostridia	L	PFAM Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Zn_ribbon_recom
PNCOCPKN_03544	622312.ROSEINA2194_01815	0.0	1029.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,248J7@186801|Clostridia	186801|Clostridia	L	resolvase	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
PNCOCPKN_03545	622312.ROSEINA2194_01814	7.67e-121	347.0	2DTU4@1|root,33MMZ@2|Bacteria,1VNW0@1239|Firmicutes,24X1J@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03549	397291.C804_04616	1.9e-57	180.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
PNCOCPKN_03550	352165.HMPREF7215_0139	5.15e-31	120.0	COG2265@1|root,COG2265@2|Bacteria,3TAIZ@508458|Synergistetes	508458|Synergistetes	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
PNCOCPKN_03551	1294142.CINTURNW_2236	4.78e-32	116.0	2E02D@1|root,32VRF@2|Bacteria,1VMM5@1239|Firmicutes,24RD3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03552	520999.PROVALCAL_00915	3.64e-18	96.7	COG1864@1|root,COG3210@1|root,COG1864@2|Bacteria,COG3210@2|Bacteria,1MX2K@1224|Proteobacteria,1RNRK@1236|Gammaproteobacteria,3ZA1G@586|Providencia	1236|Gammaproteobacteria	U	Filamentous hemeagglutinin family domain protein	fhaB	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	ESPR,Fil_haemagg,Fil_haemagg_2,Haemagg_act,PT-VENN
PNCOCPKN_03554	518635.BIFANG_03294	6.62e-50	176.0	2CWIF@1|root,32SZQ@2|Bacteria,2HZYA@201174|Actinobacteria,4D289@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03555	246199.CUS_7966	1.57e-112	329.0	28MIG@1|root,2ZAV8@2|Bacteria,1V2VJ@1239|Firmicutes,24G9N@186801|Clostridia,3WIWW@541000|Ruminococcaceae	186801|Clostridia	S	EcsC protein family	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
PNCOCPKN_03556	622312.ROSEINA2194_02109	1.01e-23	91.7	COG3070@1|root,COG3070@2|Bacteria,1V42M@1239|Firmicutes,24JNV@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
PNCOCPKN_03557	796942.HMPREF9623_01343	5.7e-08	51.2	COG3070@1|root,COG3070@2|Bacteria,1V42M@1239|Firmicutes,24JNV@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
PNCOCPKN_03559	1280698.AUJS01000056_gene1441	5.31e-177	499.0	COG1502@1|root,COG1502@2|Bacteria,1TRJE@1239|Firmicutes,248ZE@186801|Clostridia	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
PNCOCPKN_03560	883109.HMPREF0380_01476	2.18e-62	192.0	COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,24JGY@186801|Clostridia,3WDDV@538999|Clostridiales incertae sedis	186801|Clostridia	P	ArsC family	spxA	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
PNCOCPKN_03561	411474.COPEUT_00684	2.98e-78	238.0	COG1102@1|root,COG1102@2|Bacteria,1V4ZA@1239|Firmicutes	1239|Firmicutes	F	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
PNCOCPKN_03562	1280694.AUJQ01000020_gene6	1.81e-55	178.0	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,24JAK@186801|Clostridia	186801|Clostridia	C	Bacterial transferase hexapeptide	PaaY	-	-	ko:K02617	-	-	-	-	ko00000	-	-	-	Hexapep,Hexapep_2
PNCOCPKN_03563	411462.DORLON_02338	6.14e-296	809.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,27UZZ@189330|Dorea	186801|Clostridia	H	Cys/Met metabolism PLP-dependent enzyme	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
PNCOCPKN_03564	585394.RHOM_13220	0.0	1056.0	COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,24978@186801|Clostridia	186801|Clostridia	P	Sulfate transporter	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
PNCOCPKN_03565	97139.C824_03803	3.73e-86	268.0	28M3R@1|root,32UZU@2|Bacteria,1VBVW@1239|Firmicutes,24J58@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03566	1121115.AXVN01000018_gene43	1.25e-149	434.0	COG0503@1|root,COG0503@2|Bacteria,1UZSF@1239|Firmicutes,24FUM@186801|Clostridia,3Y1E0@572511|Blautia	186801|Clostridia	F	Phosphoribosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PRTase_2,TRSP
PNCOCPKN_03567	457412.RSAG_01638	1.11e-201	564.0	COG1358@1|root,COG1358@2|Bacteria,1TP5Y@1239|Firmicutes,2487J@186801|Clostridia,3WH6S@541000|Ruminococcaceae	186801|Clostridia	J	PELOTA RNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PELOTA_1,PRTase_1,PRTase_2,TRSP
PNCOCPKN_03568	457412.RSAG_01637	2.63e-169	479.0	COG2301@1|root,COG2301@2|Bacteria,1TSF2@1239|Firmicutes,249TC@186801|Clostridia,3WJ19@541000|Ruminococcaceae	186801|Clostridia	G	C-C_Bond_Lyase of the TIM-Barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	C-C_Bond_Lyase
PNCOCPKN_03569	397288.C806_01988	4.53e-97	286.0	COG0705@1|root,COG0705@2|Bacteria,1V1C3@1239|Firmicutes,24GPR@186801|Clostridia,27KQ7@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Rhomboid family	-	-	-	ko:K02441	-	-	-	-	ko00000	-	-	-	Rhomboid
PNCOCPKN_03570	1121115.AXVN01000018_gene46	0.0	1167.0	2BVVP@1|root,2Z9CR@2|Bacteria,1TRYC@1239|Firmicutes,2487Q@186801|Clostridia,3Y1D8@572511|Blautia	186801|Clostridia	S	Putative component of 'biosynthetic module'	-	-	-	-	-	-	-	-	-	-	-	-	YceG_bac
PNCOCPKN_03571	1121115.AXVN01000018_gene47	1.07e-207	582.0	COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,3Y1EX@572511|Blautia	186801|Clostridia	P	Toxic anion resistance protein (TelA)	-	-	-	-	-	-	-	-	-	-	-	-	TelA
PNCOCPKN_03572	397291.C804_02843	5.72e-124	354.0	COG2310@1|root,COG2310@2|Bacteria,1TNZQ@1239|Firmicutes,24A3Y@186801|Clostridia,27K57@186928|unclassified Lachnospiraceae	186801|Clostridia	T	TerD domain	terD_2	-	-	ko:K05795	-	-	-	-	ko00000	-	-	-	TerD
PNCOCPKN_03573	1121115.AXVN01000018_gene50	5.68e-113	327.0	COG2310@1|root,COG2310@2|Bacteria,1TR98@1239|Firmicutes,24FZM@186801|Clostridia,3Y13G@572511|Blautia	186801|Clostridia	T	TerD domain	yceC	-	-	-	-	-	-	-	-	-	-	-	TerD
PNCOCPKN_03574	1121115.AXVN01000018_gene51	0.0	1406.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,3XZ0A@572511|Blautia	186801|Clostridia	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
PNCOCPKN_03575	1235799.C818_01135	1.15e-93	283.0	COG0561@1|root,COG0561@2|Bacteria,1V24C@1239|Firmicutes,24HGT@186801|Clostridia,27N1C@186928|unclassified Lachnospiraceae	186801|Clostridia	S	hydrolases of the HAD superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3,S6PP
PNCOCPKN_03576	575593.HMPREF0491_01365	1.05e-128	370.0	COG2013@1|root,COG2013@2|Bacteria,1TSVH@1239|Firmicutes,24DQR@186801|Clostridia,27JVP@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
PNCOCPKN_03577	679200.HMPREF9333_01426	1.08e-86	266.0	COG2310@1|root,COG2310@2|Bacteria,1V26C@1239|Firmicutes,24GMA@186801|Clostridia	186801|Clostridia	T	TerD domain	-	-	-	-	-	-	-	-	-	-	-	-	TerD
PNCOCPKN_03578	1410626.JHXB01000003_gene1076	0.000519	45.1	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	ligA1	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF3494
PNCOCPKN_03580	397291.C804_02030	1.06e-283	813.0	COG3250@1|root,COG3250@2|Bacteria,1TS96@1239|Firmicutes,248B9@186801|Clostridia,27JAC@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolases family 2	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
PNCOCPKN_03581	585394.RHOM_10595	9.57e-134	385.0	COG0596@1|root,COG0596@2|Bacteria,1TSU3@1239|Firmicutes,24DYW@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03582	585394.RHOM_10580	6.36e-282	775.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
PNCOCPKN_03583	1519439.JPJG01000076_gene865	1.27e-28	114.0	COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,249IU@186801|Clostridia,2N8QT@216572|Oscillospiraceae	186801|Clostridia	O	Uncharacterized protein family (UPF0051)	sufB	-	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
PNCOCPKN_03584	1235800.C819_01897	2.24e-132	379.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,27IBR@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PNCOCPKN_03585	658086.HMPREF0994_04912	1.52e-274	802.0	COG0577@1|root,COG1511@1|root,COG0577@2|Bacteria,COG1511@2|Bacteria,1TPHU@1239|Firmicutes,248RV@186801|Clostridia,27IXQ@186928|unclassified Lachnospiraceae	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PNCOCPKN_03586	585394.RHOM_04695	2.42e-115	333.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	cmk	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
PNCOCPKN_03587	622312.ROSEINA2194_02909	2.92e-118	348.0	COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,24DE3@186801|Clostridia	186801|Clostridia	P	transport protein CorA	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
PNCOCPKN_03588	1280390.CBQR020000077_gene1694	2.79e-120	352.0	COG1116@1|root,COG1116@2|Bacteria,1TSW5@1239|Firmicutes,4HAFM@91061|Bacilli,26QI3@186822|Paenibacillaceae	91061|Bacilli	P	ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	-	-	-	ko:K15555	ko00920,ko02010,map00920,map02010	M00436	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.17.2	-	-	ABC_tran
PNCOCPKN_03589	663278.Ethha_1750	1.8e-104	312.0	COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,247VM@186801|Clostridia,3WHIC@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport system permease component	ssuC_2	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
PNCOCPKN_03590	1232443.BAIA02000064_gene1097	9.89e-127	374.0	COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,248IG@186801|Clostridia	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
PNCOCPKN_03591	585394.RHOM_13210	5.79e-37	125.0	2E45D@1|root,32Z1F@2|Bacteria,1VEXR@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03592	622312.ROSEINA2194_02907	0.0	1158.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
PNCOCPKN_03593	585394.RHOM_13205	1.32e-72	222.0	2E5KN@1|root,330BS@2|Bacteria,1V5P2@1239|Firmicutes,24IND@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03594	585394.RHOM_13200	0.0	1153.0	28IKE@1|root,2Z8M5@2|Bacteria,1TP2B@1239|Firmicutes,248C2@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	GcvP	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
PNCOCPKN_03595	585394.RHOM_13195	2.9e-47	152.0	COG1925@1|root,COG1925@2|Bacteria,1UFZA@1239|Firmicutes,24MM8@186801|Clostridia	186801|Clostridia	G	Phosphocarrier protein (Hpr)	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
PNCOCPKN_03596	622312.ROSEINA2194_02903	2.05e-32	121.0	2E7V3@1|root,3329Y@2|Bacteria,1VHFN@1239|Firmicutes,24SN8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03597	585394.RHOM_13185	6.04e-271	743.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia	186801|Clostridia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
PNCOCPKN_03598	585394.RHOM_13180	1.94e-174	493.0	COG1484@1|root,COG1484@2|Bacteria,1TPKM@1239|Firmicutes,2483D@186801|Clostridia	186801|Clostridia	L	DNA replication protein	dnaC	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
PNCOCPKN_03599	622312.ROSEINA2194_03797	5.86e-142	414.0	COG3935@1|root,COG3935@2|Bacteria,1TPR5@1239|Firmicutes,248E7@186801|Clostridia	186801|Clostridia	L	DnaD domain protein	dnaD	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
PNCOCPKN_03600	622312.ROSEINA2194_03795	2.7e-285	785.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
PNCOCPKN_03601	585394.RHOM_13160	1.49e-260	719.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,24943@186801|Clostridia	186801|Clostridia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
PNCOCPKN_03602	585394.RHOM_13155	2.53e-246	679.0	COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia	186801|Clostridia	G	glucose-1-phosphate adenylyltransferase GlgD subunit	glgD	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
PNCOCPKN_03603	622312.ROSEINA2194_01451	5.91e-51	161.0	COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,24MVQ@186801|Clostridia	186801|Clostridia	D	Could be involved in septation	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
PNCOCPKN_03604	585394.RHOM_13145	1.18e-144	411.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,248Z3@186801|Clostridia	186801|Clostridia	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
PNCOCPKN_03605	622312.ROSEINA2194_01453	3.06e-113	327.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
PNCOCPKN_03606	585394.RHOM_13135	0.0	1954.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
PNCOCPKN_03607	622312.ROSEINA2194_01455	4.64e-131	385.0	2DCHY@1|root,2ZE7V@2|Bacteria,1UMSB@1239|Firmicutes,25FCG@186801|Clostridia	186801|Clostridia	-	-	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2
PNCOCPKN_03608	622312.ROSEINA2194_01457	1.09e-86	259.0	COG0703@1|root,COG0703@2|Bacteria,1V3W6@1239|Firmicutes,24HKA@186801|Clostridia	186801|Clostridia	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
PNCOCPKN_03609	585394.RHOM_02240	1.5e-206	590.0	COG0739@1|root,COG1388@1|root,COG3583@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,COG3583@2|Bacteria,1TRWJ@1239|Firmicutes,24A2J@186801|Clostridia	186801|Clostridia	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	G5,LysM,Peptidase_M23
PNCOCPKN_03610	622312.ROSEINA2194_01459	1.08e-274	755.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia	186801|Clostridia	M	Belongs to the EPSP synthase family. MurA subfamily	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
PNCOCPKN_03612	1256908.HMPREF0373_02800	1.19e-83	256.0	COG3619@1|root,COG3619@2|Bacteria,1VBGA@1239|Firmicutes,24KG3@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
PNCOCPKN_03613	585394.RHOM_02270	6.81e-156	449.0	COG2206@1|root,COG2206@2|Bacteria,1TR95@1239|Firmicutes,25AZS@186801|Clostridia	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
PNCOCPKN_03614	585394.RHOM_02275	2.38e-273	749.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
PNCOCPKN_03615	585394.RHOM_02280	1.1e-277	769.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,1TPVJ@1239|Firmicutes,2489X@186801|Clostridia	186801|Clostridia	T	Histidine kinase- DNA gyrase B	yycG_1	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
PNCOCPKN_03616	585394.RHOM_02285	8.99e-157	440.0	COG0745@1|root,COG0745@2|Bacteria,1TPRU@1239|Firmicutes,24843@186801|Clostridia	186801|Clostridia	KT	response regulator receiver	srrA_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PNCOCPKN_03617	585394.RHOM_02290	3.14e-26	99.0	28TG6@1|root,2ZFQ4@2|Bacteria,1W51P@1239|Firmicutes,2575E@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03618	622312.ROSEINA2194_01477	1.04e-110	323.0	COG0564@1|root,COG0564@2|Bacteria,1TX59@1239|Firmicutes,24HTV@186801|Clostridia	186801|Clostridia	J	Pseudouridine synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
PNCOCPKN_03619	585394.RHOM_02305	0.0	908.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
PNCOCPKN_03620	397291.C804_00766	7.16e-231	696.0	COG0457@1|root,COG2199@1|root,COG0457@2|Bacteria,COG2199@2|Bacteria,1VQTU@1239|Firmicutes,24D8M@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
PNCOCPKN_03621	622312.ROSEINA2194_01481	9.02e-245	681.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia	186801|Clostridia	J	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
PNCOCPKN_03622	585394.RHOM_02315	7.31e-144	417.0	COG2334@1|root,COG2334@2|Bacteria,1TTBS@1239|Firmicutes,2483F@186801|Clostridia	186801|Clostridia	S	spore coat protein, CotS	cotS	-	-	ko:K06331,ko:K06337	-	-	-	-	ko00000	-	-	-	APH,Choline_kinase
PNCOCPKN_03623	585394.RHOM_02320	8.39e-137	409.0	28JT6@1|root,2Z9II@2|Bacteria,1V7ZW@1239|Firmicutes,24H3G@186801|Clostridia	186801|Clostridia	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
PNCOCPKN_03624	622312.ROSEINA2194_01484	0.0	1046.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia	186801|Clostridia	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain II	pgcA	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
PNCOCPKN_03626	622312.ROSEINA2194_01485	1.04e-50	161.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
PNCOCPKN_03627	585394.RHOM_02340	2.46e-44	144.0	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,24QNF@186801|Clostridia	186801|Clostridia	J	S4 domain protein	hslR	-	-	-	-	-	-	-	-	-	-	-	S4
PNCOCPKN_03628	622312.ROSEINA2194_01487	1.24e-51	164.0	2E3ZZ@1|root,32YWW@2|Bacteria,1VEIW@1239|Firmicutes,24QNQ@186801|Clostridia	186801|Clostridia	S	Sporulation protein YabP	yabP	-	-	-	-	-	-	-	-	-	-	-	YabP
PNCOCPKN_03629	622312.ROSEINA2194_01488	1.13e-53	173.0	2EFTM@1|root,32YR5@2|Bacteria,1VEV2@1239|Firmicutes	1239|Firmicutes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YabQ
PNCOCPKN_03630	622312.ROSEINA2194_01489	2.92e-34	120.0	COG2919@1|root,COG2919@2|Bacteria,1VGPP@1239|Firmicutes,24R6M@186801|Clostridia	186801|Clostridia	D	septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
PNCOCPKN_03631	622312.ROSEINA2194_01490	5.33e-213	591.0	COG0667@1|root,COG0667@2|Bacteria,1TRS0@1239|Firmicutes,247RJ@186801|Clostridia	186801|Clostridia	C	aldo keto reductase	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
PNCOCPKN_03632	622312.ROSEINA2194_01491	4.75e-310	860.0	COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,247XG@186801|Clostridia	186801|Clostridia	KT	stage ii sporulation protein e	spoIIE	-	3.1.3.16	ko:K06382	-	-	-	-	ko00000,ko01000	-	-	-	SpoIIE
PNCOCPKN_03633	585394.RHOM_02375	1.61e-161	473.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
PNCOCPKN_03634	585394.RHOM_02380	9.54e-101	294.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
PNCOCPKN_03635	585394.RHOM_02385	0.0	1014.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
PNCOCPKN_03636	1280688.AUJB01000008_gene509	5.63e-164	469.0	COG1613@1|root,COG1613@2|Bacteria,1TS25@1239|Firmicutes,24B9S@186801|Clostridia,3NI27@46205|Pseudobutyrivibrio	186801|Clostridia	P	PBP superfamily domain	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
PNCOCPKN_03637	515620.EUBELI_01885	1.18e-156	444.0	COG0555@1|root,COG0555@2|Bacteria,1TQHR@1239|Firmicutes,24ACM@186801|Clostridia,25ZFW@186806|Eubacteriaceae	186801|Clostridia	O	Binding-protein-dependent transport system inner membrane component	cysT	-	-	ko:K02046,ko:K15496	ko00920,ko02010,map00920,map02010	M00185,M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3,3.A.1.6.5	-	-	BPD_transp_1
PNCOCPKN_03638	515620.EUBELI_01884	4.54e-148	422.0	COG4208@1|root,COG4208@2|Bacteria,1TS3N@1239|Firmicutes,24C3X@186801|Clostridia,25VWA@186806|Eubacteriaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
PNCOCPKN_03639	515620.EUBELI_01883	1.49e-168	481.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,25W0F@186806|Eubacteriaceae	186801|Clostridia	E	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	-	3.6.3.25	ko:K02045,ko:K02052	ko00920,ko02010,ko02024,map00920,map02010,map02024	M00185,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_2
PNCOCPKN_03640	1121115.AXVN01000104_gene849	4.32e-278	776.0	COG1053@1|root,COG1053@2|Bacteria,1TRE8@1239|Firmicutes,247TH@186801|Clostridia,3Y0UM@572511|Blautia	186801|Clostridia	C	FAD binding domain	aprA	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
PNCOCPKN_03641	515620.EUBELI_01895	3.76e-50	160.0	COG1146@1|root,COG1146@2|Bacteria,1VADW@1239|Firmicutes,24MQA@186801|Clostridia,25X48@186806|Eubacteriaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_9
PNCOCPKN_03642	1121115.AXVN01000104_gene847	9.04e-198	552.0	COG0175@1|root,COG0175@2|Bacteria,1U1VN@1239|Firmicutes,248Y9@186801|Clostridia,3Y143@572511|Blautia	186801|Clostridia	H	Phosphoadenosine phosphosulfate reductase family	cysD	-	1.8.4.10,1.8.4.8,2.7.7.4	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R02021,R04929	RC00007,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
PNCOCPKN_03643	1449050.JNLE01000003_gene3109	1.42e-280	781.0	COG2895@1|root,COG2895@2|Bacteria,1UI8R@1239|Firmicutes,249BX@186801|Clostridia,36FE5@31979|Clostridiaceae	186801|Clostridia	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
PNCOCPKN_03644	585394.RHOM_02390	2.59e-201	585.0	COG2206@1|root,COG2206@2|Bacteria,1V6IE@1239|Firmicutes,24K4Y@186801|Clostridia	186801|Clostridia	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
PNCOCPKN_03645	622312.ROSEINA2194_01501	0.0	1146.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	tvaI	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,Alpha-amylase_N
PNCOCPKN_03648	585394.RHOM_12785	6.88e-187	543.0	COG0840@1|root,COG3290@1|root,COG0840@2|Bacteria,COG3290@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
PNCOCPKN_03649	585394.RHOM_12780	0.0	1127.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
PNCOCPKN_03650	585394.RHOM_01265	5.07e-165	467.0	2E1XD@1|root,32X6E@2|Bacteria,1VC0W@1239|Firmicutes,24P6H@186801|Clostridia	186801|Clostridia	S	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
PNCOCPKN_03651	585394.RHOM_01325	4.6e-97	284.0	COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,24I4E@186801|Clostridia	186801|Clostridia	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
PNCOCPKN_03652	585394.RHOM_01330	1.49e-89	267.0	COG3247@1|root,COG3247@2|Bacteria,1VBAR@1239|Firmicutes,25CUJ@186801|Clostridia	186801|Clostridia	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
PNCOCPKN_03653	622312.ROSEINA2194_02398	1.46e-230	652.0	COG2199@1|root,COG2206@1|root,COG2199@2|Bacteria,COG2206@2|Bacteria,1V6WM@1239|Firmicutes,24FPG@186801|Clostridia	186801|Clostridia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF,HD,HD_5,HisKA_7TM
PNCOCPKN_03654	622312.ROSEINA2194_02399	4.22e-41	135.0	2E7JQ@1|root,3321V@2|Bacteria,1VH9B@1239|Firmicutes,24S7B@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03655	622312.ROSEINA2194_02400	1.48e-163	468.0	COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,248S5@186801|Clostridia	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
PNCOCPKN_03656	585394.RHOM_01380	3.79e-106	309.0	COG1309@1|root,COG1309@2|Bacteria,1V44I@1239|Firmicutes,24I73@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
PNCOCPKN_03657	1235802.C823_05083	0.0	1008.0	COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,247R6@186801|Clostridia,25UQF@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
PNCOCPKN_03658	585394.RHOM_01390	1.43e-128	414.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia	186801|Clostridia	J	Psort location Cellwall, score	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	-
PNCOCPKN_03659	585394.RHOM_01395	1.36e-87	262.0	COG1971@1|root,COG1971@2|Bacteria,1V9RZ@1239|Firmicutes,24KSZ@186801|Clostridia	186801|Clostridia	P	Probably functions as a manganese efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	Mntp
PNCOCPKN_03660	622312.ROSEINA2194_02404	1.3e-288	808.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia	186801|Clostridia	C	Radical SAM domain protein	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,DUF4080,Radical_SAM
PNCOCPKN_03661	622312.ROSEINA2194_02405	4.63e-94	282.0	COG2176@1|root,COG2176@2|Bacteria,1V3E4@1239|Firmicutes,249X5@186801|Clostridia	186801|Clostridia	L	'dna polymerase iii	-	-	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
PNCOCPKN_03662	585394.RHOM_01415	5.81e-59	191.0	2C456@1|root,32S3D@2|Bacteria,1VBI4@1239|Firmicutes,24N4Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03664	585394.RHOM_01425	1.42e-237	669.0	COG2720@1|root,COG2720@2|Bacteria,1TSH8@1239|Firmicutes,2493X@186801|Clostridia	186801|Clostridia	V	PFAM VanW family protein	-	-	-	ko:K18346	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	G5,PG_binding_4,VanW
PNCOCPKN_03665	585394.RHOM_01430	6.98e-203	565.0	COG0309@1|root,COG0309@2|Bacteria,1TQP4@1239|Firmicutes,24963@186801|Clostridia	186801|Clostridia	O	PFAM AIR synthase related protein	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
PNCOCPKN_03666	622312.ROSEINA2194_02409	7.69e-105	303.0	COG1522@1|root,COG1522@2|Bacteria,1V3PB@1239|Firmicutes,24I3N@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, AsnC family	Lrp	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
PNCOCPKN_03667	585394.RHOM_01440	4.23e-266	730.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia	186801|Clostridia	E	PFAM aminotransferase class I and II	aspC	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
PNCOCPKN_03668	585394.RHOM_01445	2.06e-121	346.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,24HVV@186801|Clostridia	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
PNCOCPKN_03669	585394.RHOM_01450	3.84e-180	504.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA2	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
PNCOCPKN_03670	585394.RHOM_01455	1.04e-191	534.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA2	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
PNCOCPKN_03671	622312.ROSEINA2194_02414	9.99e-163	459.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,248AB@186801|Clostridia	186801|Clostridia	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfT	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
PNCOCPKN_03672	585394.RHOM_01465	3.51e-150	426.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
PNCOCPKN_03673	1415775.U729_2947	1.89e-36	129.0	2E529@1|root,32ZVG@2|Bacteria,1VGFJ@1239|Firmicutes,24R64@186801|Clostridia,36NH8@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
PNCOCPKN_03674	1235798.C817_02114	3.03e-102	313.0	COG0515@1|root,COG0515@2|Bacteria,1V7U3@1239|Firmicutes,25AZB@186801|Clostridia	186801|Clostridia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
PNCOCPKN_03675	1235798.C817_02113	2.02e-17	74.3	2EJDK@1|root,33D4M@2|Bacteria,1VPVH@1239|Firmicutes,24VVZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RHH_5
PNCOCPKN_03676	476272.RUMHYD_01730	1.5e-57	188.0	2DPEI@1|root,331RX@2|Bacteria,1VIYX@1239|Firmicutes,24REE@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF5067)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4352
PNCOCPKN_03677	585394.RHOM_01470	1.68e-98	286.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
PNCOCPKN_03678	585394.RHOM_01475	3.52e-83	246.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
PNCOCPKN_03679	702450.CUW_0318	1.52e-16	78.2	COG1309@1|root,COG1309@2|Bacteria,1V8TI@1239|Firmicutes,3VTTK@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
PNCOCPKN_03680	1230342.CTM_05143	3.43e-22	95.1	COG3315@1|root,COG3315@2|Bacteria,1TSGJ@1239|Firmicutes,24IYG@186801|Clostridia,36GVF@31979|Clostridiaceae	186801|Clostridia	Q	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	LCM
PNCOCPKN_03681	1536774.H70357_11880	3.5e-28	111.0	COG3315@1|root,COG3315@2|Bacteria,1TSGJ@1239|Firmicutes,4HCZS@91061|Bacilli,26V7A@186822|Paenibacillaceae	91061|Bacilli	Q	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	LCM
PNCOCPKN_03682	1226325.HMPREF1548_05583	0.0	1424.0	COG3957@1|root,COG3957@2|Bacteria,1TR23@1239|Firmicutes,24B8I@186801|Clostridia,36G82@31979|Clostridiaceae	186801|Clostridia	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
PNCOCPKN_03683	1235798.C817_05228	6.81e-117	350.0	COG0662@1|root,COG2169@1|root,COG0662@2|Bacteria,COG2169@2|Bacteria,1V9CR@1239|Firmicutes,24K6B@186801|Clostridia,27WPH@189330|Dorea	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
PNCOCPKN_03684	622312.ROSEINA2194_04066	1.29e-69	237.0	COG0840@1|root,COG0840@2|Bacteria,1V0JG@1239|Firmicutes,24A5M@186801|Clostridia	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
PNCOCPKN_03685	1449050.JNLE01000003_gene675	5.71e-75	234.0	COG3279@1|root,COG3279@2|Bacteria,1TSDB@1239|Firmicutes,24MQ4@186801|Clostridia,36KUT@31979|Clostridiaceae	186801|Clostridia	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
PNCOCPKN_03686	1541959.KQ51_01201	3.95e-99	298.0	COG3290@1|root,COG3290@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K11614	ko02020,map02020	M00490	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c_5,PAS_9,SPOB_a
PNCOCPKN_03687	1449050.JNLE01000003_gene677	1.47e-174	516.0	COG1132@1|root,COG1132@2|Bacteria,1TPZP@1239|Firmicutes,249WV@186801|Clostridia,36EX9@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
PNCOCPKN_03688	1449050.JNLE01000003_gene678	4.86e-191	557.0	COG1132@1|root,COG1132@2|Bacteria,1TPZP@1239|Firmicutes,249WV@186801|Clostridia,36EX9@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
PNCOCPKN_03689	180332.JTGN01000011_gene619	5.08e-36	157.0	COG4870@1|root,COG5492@1|root,COG4870@2|Bacteria,COG5492@2|Bacteria,1V2GU@1239|Firmicutes,24GPX@186801|Clostridia	186801|Clostridia	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2,Flg_new,Peptidase_C1
PNCOCPKN_03690	585394.RHOM_05265	2.39e-68	233.0	2C4YK@1|root,342PE@2|Bacteria,1VWY9@1239|Firmicutes,24TZZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03692	861454.HMPREF9099_02905	1.03e-06	48.1	COG3514@1|root,COG3514@2|Bacteria,1VFWT@1239|Firmicutes,24S45@186801|Clostridia,27PNA@186928|unclassified Lachnospiraceae	186801|Clostridia	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
PNCOCPKN_03693	585394.RHOM_15945	5.29e-93	286.0	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03694	999413.HMPREF1094_00335	1.97e-119	350.0	COG3547@1|root,COG3547@2|Bacteria,1TPSP@1239|Firmicutes,3VRH5@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
PNCOCPKN_03695	1280698.AUJS01000074_gene594	2.59e-173	485.0	COG3267@1|root,COG3267@2|Bacteria,1TRGM@1239|Firmicutes,24BFG@186801|Clostridia	186801|Clostridia	U	SMART AAA ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
PNCOCPKN_03701	585394.RHOM_04790	4.58e-279	769.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia	186801|Clostridia	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
PNCOCPKN_03702	1235790.C805_03039	7.1e-121	407.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Flg_new,LRR_5,Peptidase_M26_N,SLH,fn3
PNCOCPKN_03704	585394.RHOM_04785	9.41e-75	225.0	2AU16@1|root,31JM9@2|Bacteria,1V6CJ@1239|Firmicutes,24JBF@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03705	622312.ROSEINA2194_03436	0.0	1234.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
PNCOCPKN_03706	622312.ROSEINA2194_03438	1.71e-21	105.0	COG5184@1|root,COG5184@2|Bacteria,1VDTD@1239|Firmicutes,25FD2@186801|Clostridia	186801|Clostridia	DZ	Cadherin-like beta sandwich domain	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like
PNCOCPKN_03707	585394.RHOM_04750	1.41e-161	458.0	COG1313@1|root,COG1313@2|Bacteria,1TRUV@1239|Firmicutes,247VW@186801|Clostridia	186801|Clostridia	C	radical SAM domain protein	PflX	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
PNCOCPKN_03708	585394.RHOM_04745	7.58e-257	709.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
PNCOCPKN_03709	585394.RHOM_04740	1.93e-195	545.0	COG0657@1|root,COG0657@2|Bacteria,1UZ7B@1239|Firmicutes,25B2C@186801|Clostridia	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	3.1.1.83	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
PNCOCPKN_03710	585394.RHOM_04735	4.16e-110	322.0	2B3FQ@1|root,31W4P@2|Bacteria,1V6XF@1239|Firmicutes,24KDR@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03711	585394.RHOM_04730	1.48e-273	753.0	COG4908@1|root,COG4908@2|Bacteria,1TQXH@1239|Firmicutes,24B2C@186801|Clostridia	186801|Clostridia	I	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	AATase
PNCOCPKN_03714	622312.ROSEINA2194_03381	5.37e-289	790.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
PNCOCPKN_03715	1235790.C805_00793	3.64e-36	124.0	COG3326@1|root,COG3326@2|Bacteria,1VEJY@1239|Firmicutes,24QJW@186801|Clostridia,25XSB@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1294
PNCOCPKN_03716	585394.RHOM_11730	0.0	1073.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,247X8@186801|Clostridia	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
PNCOCPKN_03717	585394.RHOM_11735	2.52e-314	858.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,248DD@186801|Clostridia	186801|Clostridia	C	Radical SAM	scfB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
PNCOCPKN_03718	1256908.HMPREF0373_02435	7.28e-20	80.9	2EGRK@1|root,33AHS@2|Bacteria,1VK9R@1239|Firmicutes,24UM0@186801|Clostridia,25XQV@186806|Eubacteriaceae	186801|Clostridia	S	Six-cysteine peptide SCIFF	scfA	-	-	-	-	-	-	-	-	-	-	-	SCIFF
PNCOCPKN_03719	476272.RUMHYD_00772	4.26e-267	739.0	COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia,3XYP4@572511|Blautia	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	pbuX	-	-	ko:K03458	-	-	-	-	ko00000	2.A.40	-	-	Xan_ur_permease
PNCOCPKN_03720	585394.RHOM_11745	3.9e-41	140.0	2E3KV@1|root,32YJ5@2|Bacteria,1VEHD@1239|Firmicutes,24RP3@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF3792
PNCOCPKN_03721	585394.RHOM_11750	9.18e-163	461.0	COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,24AQ8@186801|Clostridia	186801|Clostridia	G	Aldose 1-epimerase	lacX	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
PNCOCPKN_03722	1469948.JPNB01000002_gene2779	1.89e-113	330.0	COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,24CPT@186801|Clostridia,36HYG@31979|Clostridiaceae	186801|Clostridia	S	channel protein, hemolysin III family	yqfA	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
PNCOCPKN_03723	585394.RHOM_11755	0.0	887.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,2484D@186801|Clostridia	186801|Clostridia	J	Asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
PNCOCPKN_03724	585394.RHOM_11760	2.36e-148	436.0	COG0544@1|root,COG0544@2|Bacteria,1V3TB@1239|Firmicutes,24I3U@186801|Clostridia	186801|Clostridia	O	Bacterial trigger factor protein (TF) C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C,Trigger_C
PNCOCPKN_03725	585394.RHOM_05010	2.38e-45	148.0	2EK04@1|root,33DQP@2|Bacteria,1VM4D@1239|Firmicutes,24WYN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03726	585394.RHOM_05425	1.32e-138	396.0	28XBK@1|root,2ZJ9G@2|Bacteria,1V203@1239|Firmicutes,24E0K@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03727	585394.RHOM_05420	1.05e-311	848.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia	186801|Clostridia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
PNCOCPKN_03728	585394.RHOM_05415	2.56e-53	169.0	COG1687@1|root,COG1687@2|Bacteria,1V9YS@1239|Firmicutes,24MSG@186801|Clostridia	186801|Clostridia	E	branched-chain amino acid	azlD	-	-	-	-	-	-	-	-	-	-	-	AzlD
PNCOCPKN_03729	585394.RHOM_05410	2.73e-135	388.0	COG1296@1|root,COG1296@2|Bacteria,1TP8P@1239|Firmicutes,248NN@186801|Clostridia	186801|Clostridia	E	branched-chain amino acid permease (azaleucine resistance)	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
PNCOCPKN_03730	585394.RHOM_05405	4.08e-64	211.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,24JDA@186801|Clostridia	186801|Clostridia	M	transglycosylase	yjbJ	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
PNCOCPKN_03731	585394.RHOM_05400	1.44e-82	246.0	COG1846@1|root,COG1846@2|Bacteria,1V1U2@1239|Firmicutes,24FR9@186801|Clostridia	186801|Clostridia	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR
PNCOCPKN_03732	622312.ROSEINA2194_02996	2.42e-165	468.0	COG0539@1|root,COG0539@2|Bacteria,1UYC5@1239|Firmicutes,24AJ1@186801|Clostridia	186801|Clostridia	J	S1 RNA binding domain protein	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
PNCOCPKN_03733	585394.RHOM_11170	2.92e-206	609.0	COG0642@1|root,COG2205@2|Bacteria,1TP73@1239|Firmicutes,248Y6@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PNCOCPKN_03734	585394.RHOM_11175	4.19e-149	421.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia	186801|Clostridia	KT	response regulator receiver	vanR3	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PNCOCPKN_03735	1235793.C809_01831	7.87e-34	119.0	COG4818@1|root,COG4818@2|Bacteria,1UN6A@1239|Firmicutes,25GXJ@186801|Clostridia,27Q73@186928|unclassified Lachnospiraceae	186801|Clostridia	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03736	1256908.HMPREF0373_00101	0.0	1416.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,25VB4@186806|Eubacteriaceae	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
PNCOCPKN_03737	622312.ROSEINA2194_02271	0.0	1928.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
PNCOCPKN_03738	585394.RHOM_04250	5.57e-174	492.0	COG0618@1|root,COG0618@2|Bacteria,1UKBY@1239|Firmicutes,24EAR@186801|Clostridia	186801|Clostridia	S	DHH family	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
PNCOCPKN_03739	622312.ROSEINA2194_02268	2.33e-104	306.0	COG0546@1|root,COG0546@2|Bacteria,1V4W6@1239|Firmicutes,24DB6@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
PNCOCPKN_03740	622312.ROSEINA2194_02267	6.21e-282	780.0	COG2317@1|root,COG2317@2|Bacteria,1TPS6@1239|Firmicutes,249NK@186801|Clostridia	186801|Clostridia	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
PNCOCPKN_03741	585394.RHOM_03855	1.56e-256	703.0	COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia	186801|Clostridia	E	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
PNCOCPKN_03742	585394.RHOM_03850	1.62e-47	160.0	2E0ER@1|root,32W16@2|Bacteria,1VDMK@1239|Firmicutes,24T4F@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
PNCOCPKN_03743	585394.RHOM_14785	6.37e-100	291.0	COG1853@1|root,COG1853@2|Bacteria,1V41U@1239|Firmicutes,24HTA@186801|Clostridia	186801|Clostridia	S	Conserved protein domain typically associated with flavoprotein oxygenases DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
PNCOCPKN_03744	478749.BRYFOR_07844	1.11e-75	242.0	COG5464@1|root,COG5464@2|Bacteria,1V3CA@1239|Firmicutes,24H4R@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
PNCOCPKN_03745	622312.ROSEINA2194_03392	3.08e-57	184.0	2AE00@1|root,313SJ@2|Bacteria,1V6FJ@1239|Firmicutes,24JFA@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03746	471875.RUMLAC_02590	0.0	916.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247PY@186801|Clostridia,3WHFU@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PNCOCPKN_03747	411463.EUBVEN_02439	0.0	879.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247VZ@186801|Clostridia,25VCK@186806|Eubacteriaceae	186801|Clostridia	P	ABC transporter, ATP-binding protein	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PNCOCPKN_03748	471875.RUMLAC_02592	2.05e-78	240.0	COG1309@1|root,COG1309@2|Bacteria,1TT2J@1239|Firmicutes,24A5X@186801|Clostridia,3WJRA@541000|Ruminococcaceae	186801|Clostridia	K	tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
PNCOCPKN_03749	622312.ROSEINA2194_00853	4.73e-128	365.0	28NMC@1|root,2ZA4G@2|Bacteria,1UYCN@1239|Firmicutes,24ACB@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
PNCOCPKN_03750	622312.ROSEINA2194_00851	0.0	1591.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolase family 3 N-terminal domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
PNCOCPKN_03751	1235798.C817_00338	1.07e-68	225.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,27VAG@189330|Dorea	186801|Clostridia	S	Predicted AAA-ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
PNCOCPKN_03752	397288.C806_03275	1.64e-09	58.5	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,27IXU@186928|unclassified Lachnospiraceae	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100,1.1.1.30	ko:K00019,ko:K00059	ko00061,ko00072,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00072,map00333,map00650,map00780,map01040,map01100,map01130,map01212	M00083,M00088,M00572	R01361,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
PNCOCPKN_03753	1274374.CBLK010000019_gene2831	8.75e-116	345.0	COG0451@1|root,COG0451@2|Bacteria,1TT3X@1239|Firmicutes,4HFYX@91061|Bacilli,26SQH@186822|Paenibacillaceae	91061|Bacilli	M	3-beta hydroxysteroid dehydrogenase	galE1	-	-	-	-	-	-	-	-	-	-	-	3Beta_HSD,Epimerase
PNCOCPKN_03755	1298920.KI911353_gene1343	1.18e-86	271.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,249HQ@186801|Clostridia,21YMB@1506553|Lachnoclostridium	186801|Clostridia	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
PNCOCPKN_03756	1410626.JHXB01000002_gene643	3.73e-88	266.0	COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,248B6@186801|Clostridia,27JG7@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PNCOCPKN_03757	658086.HMPREF0994_03731	0.0	1248.0	COG3408@1|root,COG3408@2|Bacteria,1TPY5@1239|Firmicutes,249U8@186801|Clostridia,27KIP@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
PNCOCPKN_03758	658086.HMPREF0994_03733	2.1e-129	375.0	COG1082@1|root,COG1082@2|Bacteria,1TRMY@1239|Firmicutes,24CP4@186801|Clostridia,27K31@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
PNCOCPKN_03759	478749.BRYFOR_06103	3.01e-311	862.0	COG3507@1|root,COG3507@2|Bacteria,1TQBJ@1239|Firmicutes,24CFJ@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_43
PNCOCPKN_03760	478749.BRYFOR_09770	1.13e-212	600.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
PNCOCPKN_03761	1280679.ATVX01000001_gene2951	0.0	1041.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,249UZ@186801|Clostridia,4BXZT@830|Butyrivibrio	186801|Clostridia	G	Glycosyl hydrolases family 2, sugar binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
PNCOCPKN_03762	411471.SUBVAR_04808	1.5e-225	636.0	COG2211@1|root,COG2211@2|Bacteria,1TSEH@1239|Firmicutes,24EDK@186801|Clostridia,3WNX0@541000|Ruminococcaceae	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
PNCOCPKN_03763	1506994.JNLQ01000001_gene318	9.45e-87	276.0	COG2207@1|root,COG2207@2|Bacteria,1VCDJ@1239|Firmicutes,24CSR@186801|Clostridia,4BXWP@830|Butyrivibrio	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
PNCOCPKN_03764	585394.RHOM_06075	3.87e-198	548.0	COG0235@1|root,COG0235@2|Bacteria,1TRMG@1239|Firmicutes,24BBT@186801|Clostridia	186801|Clostridia	G	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde	rhaD	-	4.1.2.19	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01785,R02263	RC00438,RC00599,RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
PNCOCPKN_03765	585394.RHOM_06070	2.92e-297	811.0	COG4806@1|root,COG4806@2|Bacteria,1TS42@1239|Firmicutes,2487G@186801|Clostridia	186801|Clostridia	G	Belongs to the rhamnose isomerase family	rhaA	-	5.3.1.14	ko:K01813	ko00051,ko01120,map00051,map01120	-	R02437	RC00434	ko00000,ko00001,ko01000	-	-	-	RhaA
PNCOCPKN_03766	585394.RHOM_06065	1e-259	721.0	COG1070@1|root,COG1070@2|Bacteria,1TP7Z@1239|Firmicutes,247ZU@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	rhaB	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
PNCOCPKN_03767	483218.BACPEC_01881	7.8e-40	161.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,2694H@186813|unclassified Clostridiales	186801|Clostridia	NT	Psort location CytoplasmicMembrane, score	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
PNCOCPKN_03768	1408436.JHXY01000035_gene1474	3.11e-200	573.0	COG3408@1|root,COG3408@2|Bacteria,1TSSU@1239|Firmicutes,24BK6@186801|Clostridia,25Y5B@186806|Eubacteriaceae	186801|Clostridia	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H
PNCOCPKN_03769	1410650.JHWL01000029_gene2151	1.9e-258	725.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,24YIP@186801|Clostridia,4BW01@830|Butyrivibrio	186801|Clostridia	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
PNCOCPKN_03770	1280673.AUJJ01000002_gene2625	1.81e-151	435.0	COG1172@1|root,COG1172@2|Bacteria,1TQVC@1239|Firmicutes,247NC@186801|Clostridia,4BXK9@830|Butyrivibrio	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
PNCOCPKN_03771	1280679.ATVX01000001_gene2777	2.1e-169	486.0	COG1609@1|root,COG1609@2|Bacteria,1UZFZ@1239|Firmicutes,248Z7@186801|Clostridia,4BWSP@830|Butyrivibrio	186801|Clostridia	K	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
PNCOCPKN_03772	1280664.AUIX01000046_gene1602	4.16e-151	434.0	COG1172@1|root,COG1172@2|Bacteria,1U0FI@1239|Firmicutes,24KVA@186801|Clostridia,4BYHY@830|Butyrivibrio	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
PNCOCPKN_03773	1280681.AUJZ01000014_gene3745	3.87e-238	669.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,4BXM3@830|Butyrivibrio	186801|Clostridia	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
PNCOCPKN_03774	1536773.R70331_07050	1.46e-181	550.0	COG2207@1|root,COG3664@1|root,COG2207@2|Bacteria,COG3664@2|Bacteria,1TQGI@1239|Firmicutes,4HE9D@91061|Bacilli,26U5K@186822|Paenibacillaceae	91061|Bacilli	K	Glycosyl hydrolases family 39	-	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	AraC_binding,Cupin_2,Glyco_hydro_39,HTH_18
PNCOCPKN_03775	1408312.JNJS01000002_gene213	2.05e-99	294.0	COG0637@1|root,COG0637@2|Bacteria,1UZE0@1239|Firmicutes,24DWR@186801|Clostridia,3NH8G@46205|Pseudobutyrivibrio	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	pgmB	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
PNCOCPKN_03776	585394.RHOM_06060	2.68e-188	528.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1TS6T@1239|Firmicutes,247QK@186801|Clostridia	186801|Clostridia	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
PNCOCPKN_03777	1235802.C823_03873	1.24e-256	720.0	COG4262@1|root,COG4262@2|Bacteria,1UYRF@1239|Firmicutes,24AHS@186801|Clostridia,25V36@186806|Eubacteriaceae	186801|Clostridia	S	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
PNCOCPKN_03778	33035.JPJF01000009_gene1487	1.93e-285	794.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,3XZE5@572511|Blautia	186801|Clostridia	S	COG NOG08812 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
PNCOCPKN_03779	622312.ROSEINA2194_00850	3.45e-233	651.0	COG3290@1|root,COG3290@2|Bacteria,1TPZT@1239|Firmicutes,2494S@186801|Clostridia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
PNCOCPKN_03780	622312.ROSEINA2194_00849	7.44e-141	401.0	COG3279@1|root,COG3279@2|Bacteria,1UHWR@1239|Firmicutes,24G6Q@186801|Clostridia	186801|Clostridia	KT	COG3279 Response regulator of the LytR AlgR family	-	-	-	ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
PNCOCPKN_03781	622312.ROSEINA2194_04390	0.0	1411.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia	186801|Clostridia	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
PNCOCPKN_03783	796942.HMPREF9623_01507	4.17e-160	468.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1UHQC@1239|Firmicutes,25EVD@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
PNCOCPKN_03784	796942.HMPREF9623_01506	7.84e-117	339.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,248XH@186801|Clostridia	186801|Clostridia	T	response regulator receiver	mprA	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PNCOCPKN_03786	622312.ROSEINA2194_04316	1.28e-80	241.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24MRZ@186801|Clostridia	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
PNCOCPKN_03787	1469948.JPNB01000002_gene3764	7.26e-21	93.2	COG1835@1|root,COG1835@2|Bacteria,1UY2A@1239|Firmicutes,24D38@186801|Clostridia,36IC7@31979|Clostridiaceae	186801|Clostridia	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
PNCOCPKN_03788	1235800.C819_01132	1.09e-37	137.0	COG1835@1|root,COG1835@2|Bacteria,1UY2A@1239|Firmicutes,24D38@186801|Clostridia,27IZK@186928|unclassified Lachnospiraceae	186801|Clostridia	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
PNCOCPKN_03789	33035.JPJF01000036_gene1748	1.91e-43	149.0	COG1476@1|root,COG1476@2|Bacteria,1UUV5@1239|Firmicutes,25KCX@186801|Clostridia,3Y0TB@572511|Blautia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PNCOCPKN_03790	585394.RHOM_15140	0.0	1050.0	COG3507@1|root,COG3507@2|Bacteria,1TSKZ@1239|Firmicutes,24BRZ@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,CBM_6,Esterase,Glyco_hydro_43
PNCOCPKN_03791	483218.BACPEC_02145	7.01e-189	539.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1TSFE@1239|Firmicutes,25KM5@186801|Clostridia,26AZA@186813|unclassified Clostridiales	186801|Clostridia	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
PNCOCPKN_03792	585394.RHOM_06150	0.0	900.0	COG0369@1|root,COG1151@2|Bacteria,1TP8X@1239|Firmicutes,247IN@186801|Clostridia	186801|Clostridia	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
PNCOCPKN_03793	1226325.HMPREF1548_02216	1.67e-119	347.0	COG1145@1|root,COG1145@2|Bacteria,1TPAZ@1239|Firmicutes,249NJ@186801|Clostridia,36F9G@31979|Clostridiaceae	186801|Clostridia	C	binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
PNCOCPKN_03794	1123075.AUDP01000001_gene2395	2.56e-96	287.0	COG0664@1|root,COG0664@2|Bacteria,1TSP9@1239|Firmicutes,24FRD@186801|Clostridia,3WIW5@541000|Ruminococcaceae	186801|Clostridia	K	Cyclic nucleotide-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
PNCOCPKN_03795	1121344.JHZO01000005_gene292	7.18e-70	230.0	COG2206@1|root,COG2206@2|Bacteria,1VV1Y@1239|Firmicutes,2502J@186801|Clostridia	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
PNCOCPKN_03796	585394.RHOM_03410	3.96e-62	208.0	COG3064@1|root,COG3064@2|Bacteria,1V52J@1239|Firmicutes,24HMZ@186801|Clostridia	186801|Clostridia	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03797	622312.ROSEINA2194_02476	1.41e-105	313.0	COG1011@1|root,COG1011@2|Bacteria,1UIG9@1239|Firmicutes,25EMR@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
PNCOCPKN_03798	585394.RHOM_03400	4.73e-101	301.0	COG1191@1|root,COG1191@2|Bacteria,1TP3Q@1239|Firmicutes,2487Z@186801|Clostridia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigF	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
PNCOCPKN_03799	585394.RHOM_03395	4.44e-69	212.0	COG2172@1|root,COG2172@2|Bacteria,1V6V2@1239|Firmicutes,24JPT@186801|Clostridia	186801|Clostridia	F	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition	spoIIAB	-	2.7.11.1	ko:K06379	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c_2
PNCOCPKN_03800	622312.ROSEINA2194_02480	2.01e-42	141.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,24R0X@186801|Clostridia	186801|Clostridia	T	Belongs to the anti-sigma-factor antagonist family	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
PNCOCPKN_03801	585394.RHOM_03385	1.56e-228	640.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,1UI34@1239|Firmicutes,25F0K@186801|Clostridia	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
PNCOCPKN_03802	622312.ROSEINA2194_02482	1.32e-20	82.4	2EGDA@1|root,33A54@2|Bacteria,1VKC8@1239|Firmicutes,24UDV@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03803	585394.RHOM_03375	3.25e-191	546.0	COG1315@1|root,COG1315@2|Bacteria,1TR7W@1239|Firmicutes,24B18@186801|Clostridia	186801|Clostridia	L	PALM domain HD hydrolase domain and	-	-	-	ko:K09749	-	-	-	-	ko00000	-	-	-	FapA,Jag_N
PNCOCPKN_03804	585394.RHOM_03370	0.0	1729.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
PNCOCPKN_03805	585394.RHOM_03360	0.0	1448.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia	186801|Clostridia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
PNCOCPKN_03807	585394.RHOM_03340	2.36e-171	482.0	COG0395@1|root,COG0395@2|Bacteria,1TS0R@1239|Firmicutes,248UX@186801|Clostridia	186801|Clostridia	P	ABC-type sugar transport system, permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
PNCOCPKN_03808	622312.ROSEINA2194_02493	1.01e-193	540.0	COG1175@1|root,COG1175@2|Bacteria,1TS63@1239|Firmicutes,2489M@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport systems permease components	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
PNCOCPKN_03809	585394.RHOM_03330	2.19e-267	741.0	COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
PNCOCPKN_03810	585394.RHOM_03325	4.2e-223	617.0	COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,24A4M@186801|Clostridia	186801|Clostridia	K	lacI family	-	-	-	ko:K02529,ko:K03604	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
PNCOCPKN_03811	585394.RHOM_03320	0.0	1519.0	COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,248YP@186801|Clostridia	186801|Clostridia	G	Glycosyltransferase 36 associated	-	-	2.4.1.20	ko:K00702	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000	-	GT36	-	Glyco_hydro_36,Glyco_transf_36
PNCOCPKN_03812	515620.EUBELI_00158	2.53e-164	463.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1V2SW@1239|Firmicutes,24GTR@186801|Clostridia,25XBA@186806|Eubacteriaceae	186801|Clostridia	K	COG2207 AraC-type DNA-binding domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
PNCOCPKN_03813	515620.EUBELI_00156	1.65e-253	704.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,25VVF@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PNCOCPKN_03814	585394.RHOM_03315	0.0	965.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia	186801|Clostridia	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
PNCOCPKN_03815	622312.ROSEINA2194_04415	6.74e-200	556.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia	186801|Clostridia	E	carbamate kinase	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
PNCOCPKN_03816	585394.RHOM_03305	1.09e-133	380.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
PNCOCPKN_03817	585394.RHOM_03300	0.0	1165.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
PNCOCPKN_03818	585394.RHOM_03295	6.72e-269	740.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
PNCOCPKN_03819	585394.RHOM_03290	6.78e-127	362.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia	186801|Clostridia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
PNCOCPKN_03820	585394.RHOM_03285	1.53e-256	711.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
PNCOCPKN_03821	397291.C804_02341	2.88e-77	243.0	COG0127@1|root,COG0127@2|Bacteria,1V85S@1239|Firmicutes,24KX4@186801|Clostridia,27NVI@186928|unclassified Lachnospiraceae	186801|Clostridia	F	Ham1 family	-	-	-	-	-	-	-	-	-	-	-	-	Ham1p_like
PNCOCPKN_03822	511680.BUTYVIB_00807	5.12e-77	233.0	COG1051@1|root,COG1051@2|Bacteria,1V3IM@1239|Firmicutes,24HEA@186801|Clostridia,4BZAJ@830|Butyrivibrio	186801|Clostridia	F	NUDIX domain	mutX	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
PNCOCPKN_03823	585394.RHOM_03230	0.0	1048.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PNCOCPKN_03824	585394.RHOM_03220	0.0	907.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PNCOCPKN_03825	1280698.AUJS01000061_gene1112	3.71e-100	296.0	COG1403@1|root,COG1403@2|Bacteria,1V5KT@1239|Firmicutes,24N2K@186801|Clostridia	186801|Clostridia	V	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03826	457421.CBFG_05938	4.01e-156	454.0	COG3950@1|root,COG3950@2|Bacteria,1UJJK@1239|Firmicutes,24CJD@186801|Clostridia	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
PNCOCPKN_03827	1235798.C817_02984	4.12e-128	379.0	COG1106@1|root,COG1106@2|Bacteria,1UJ5W@1239|Firmicutes,24G9B@186801|Clostridia,27VFY@189330|Dorea	186801|Clostridia	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K06926	-	-	-	-	ko00000	-	-	-	AAA_21
PNCOCPKN_03828	1280698.AUJS01000043_gene3334	5.73e-12	65.9	COG1106@1|root,COG1106@2|Bacteria,1UJ5W@1239|Firmicutes,24G9B@186801|Clostridia,27VFY@189330|Dorea	186801|Clostridia	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K06926	-	-	-	-	ko00000	-	-	-	AAA_21
PNCOCPKN_03829	1235792.C808_01071	7.96e-132	392.0	2DEDR@1|root,2ZMJC@2|Bacteria,1V31W@1239|Firmicutes,24FHB@186801|Clostridia,27NPX@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Bacteriophage abortive infection AbiH	-	-	-	-	-	-	-	-	-	-	-	-	AbiH
PNCOCPKN_03830	689781.AUJX01000064_gene1425	7.37e-246	715.0	COG0846@1|root,COG0846@2|Bacteria,1V11R@1239|Firmicutes,24E65@186801|Clostridia	186801|Clostridia	K	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
PNCOCPKN_03834	585394.RHOM_13865	3.8e-256	731.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
PNCOCPKN_03836	871963.Desdi_0542	1.09e-147	432.0	COG2826@1|root,COG2826@2|Bacteria,1TQ0G@1239|Firmicutes,248WB@186801|Clostridia,266TW@186807|Peptococcaceae	186801|Clostridia	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
PNCOCPKN_03838	1232453.BAIF02000019_gene3937	2.18e-41	136.0	2DRW8@1|root,32URU@2|Bacteria,1VA9A@1239|Firmicutes,24QD5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03839	657322.FPR_24010	2.54e-232	650.0	COG3378@1|root,COG3378@2|Bacteria,1TSGZ@1239|Firmicutes,24CI8@186801|Clostridia,3WHNR@541000|Ruminococcaceae	186801|Clostridia	S	Phage plasmid primase, P4 family	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	D5_N,Pox_D5
PNCOCPKN_03840	1232453.BAIF02000019_gene3934	1.89e-59	190.0	COG0358@1|root,COG0358@2|Bacteria,1V0WR@1239|Firmicutes,24C9Q@186801|Clostridia,268QU@186813|unclassified Clostridiales	186801|Clostridia	L	CHC2 zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHC2
PNCOCPKN_03841	665956.HMPREF1032_01699	8.51e-127	376.0	28ICW@1|root,2Z8F5@2|Bacteria,1TSMN@1239|Firmicutes,24BRU@186801|Clostridia,3WJHI@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03842	903814.ELI_1145	1.56e-100	306.0	COG1191@1|root,COG1191@2|Bacteria,1U0Q7@1239|Firmicutes,249NN@186801|Clostridia,25VKH@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03843	1256908.HMPREF0373_00975	2.9e-22	98.2	COG1191@1|root,COG1191@2|Bacteria,1U0Q7@1239|Firmicutes,249NN@186801|Clostridia,25VKH@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03844	622312.ROSEINA2194_01535	4.09e-290	795.0	COG3290@1|root,COG3290@2|Bacteria,1UY02@1239|Firmicutes,24BV9@186801|Clostridia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
PNCOCPKN_03845	622312.ROSEINA2194_01534	7.93e-161	451.0	COG3279@1|root,COG3279@2|Bacteria,1VA5A@1239|Firmicutes,24DB9@186801|Clostridia	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
PNCOCPKN_03846	622312.ROSEINA2194_01533	1.2e-78	234.0	COG3279@1|root,COG3279@2|Bacteria,1VAGQ@1239|Firmicutes,24Q19@186801|Clostridia	186801|Clostridia	KT	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
PNCOCPKN_03847	622312.ROSEINA2194_01532	0.0	1272.0	2CF3Z@1|root,2Z97A@2|Bacteria,1UQMP@1239|Firmicutes,248YE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03848	903814.ELI_1145	2.26e-19	87.4	COG1191@1|root,COG1191@2|Bacteria,1U0Q7@1239|Firmicutes,249NN@186801|Clostridia,25VKH@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03849	717605.Theco_0700	0.000561	45.8	COG1309@1|root,COG1309@2|Bacteria,1UYXX@1239|Firmicutes,4HH8M@91061|Bacilli,26Y0V@186822|Paenibacillaceae	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
PNCOCPKN_03850	633147.Olsu_0240	3.1e-205	580.0	COG5361@1|root,COG5361@2|Bacteria,2GRDZ@201174|Actinobacteria,4CX4F@84998|Coriobacteriia	84998|Coriobacteriia	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
PNCOCPKN_03851	903814.ELI_2151	3.07e-288	810.0	COG2015@1|root,COG2015@2|Bacteria,1TR7Q@1239|Firmicutes,248SN@186801|Clostridia,25Y8G@186806|Eubacteriaceae	186801|Clostridia	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
PNCOCPKN_03852	1235802.C823_05093	9.92e-64	201.0	COG1595@1|root,COG1595@2|Bacteria,1V6SV@1239|Firmicutes,24HPR@186801|Clostridia,25X89@186806|Eubacteriaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ECF,Sigma70_r2,Sigma70_r4,Sigma70_r4_2
PNCOCPKN_03853	1235802.C823_05092	7.69e-121	384.0	COG1948@1|root,COG4880@2|Bacteria,1TQK0@1239|Firmicutes,247VC@186801|Clostridia,25WEQ@186806|Eubacteriaceae	186801|Clostridia	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
PNCOCPKN_03855	632245.CLP_0713	5.29e-134	386.0	COG0657@1|root,COG0657@2|Bacteria,1TP1H@1239|Firmicutes,24D7F@186801|Clostridia,36E3F@31979|Clostridiaceae	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
PNCOCPKN_03856	622312.ROSEINA2194_02236	1.79e-287	786.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
PNCOCPKN_03858	622312.ROSEINA2194_02923	9.12e-69	212.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
PNCOCPKN_03859	1235793.C809_01302	6.98e-126	382.0	2BP58@1|root,32HW3@2|Bacteria,1V8J8@1239|Firmicutes,24HB1@186801|Clostridia,27PAY@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4367
PNCOCPKN_03860	585394.RHOM_00275	8.74e-154	437.0	COG0561@1|root,COG0561@2|Bacteria,1UFDJ@1239|Firmicutes,25B6S@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
PNCOCPKN_03862	411459.RUMOBE_02700	5.83e-95	281.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HU5@186801|Clostridia,3Y18Q@572511|Blautia	186801|Clostridia	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
PNCOCPKN_03863	411459.RUMOBE_02699	1.73e-220	610.0	COG0502@1|root,COG0502@2|Bacteria,1TPQ4@1239|Firmicutes,248J4@186801|Clostridia,3XYUJ@572511|Blautia	186801|Clostridia	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
PNCOCPKN_03864	411459.RUMOBE_02698	8.32e-128	367.0	COG0132@1|root,COG0132@2|Bacteria,1UYA3@1239|Firmicutes,24F15@186801|Clostridia,3Y0X3@572511|Blautia	186801|Clostridia	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
PNCOCPKN_03865	411459.RUMOBE_02697	8.54e-268	735.0	COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,25E7B@186801|Clostridia,3Y0YH@572511|Blautia	186801|Clostridia	H	Aminotransferase class-III	bioA	-	2.6.1.113,2.6.1.55,2.6.1.62,2.6.1.77	ko:K00833,ko:K03851,ko:K12256,ko:K15372	ko00330,ko00410,ko00430,ko00780,ko01100,map00330,map00410,map00430,map00780,map01100	M00123,M00573,M00577	R00908,R01684,R03231,R05652,R08714	RC00006,RC00008,RC00062,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
PNCOCPKN_03866	1408323.JQKK01000024_gene1322	1.28e-09	55.8	2DQE4@1|root,3368Z@2|Bacteria,1VJUF@1239|Firmicutes,24UJT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03867	585394.RHOM_00305	0.0	1207.0	COG0674@1|root,COG1013@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia	186801|Clostridia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K00169,ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N,TPP_enzyme_C
PNCOCPKN_03868	585394.RHOM_00310	7.36e-196	550.0	COG1014@1|root,COG1144@1|root,COG1014@2|Bacteria,COG1144@2|Bacteria,1TRFJ@1239|Firmicutes,24A29@186801|Clostridia	186801|Clostridia	C	oxidoreductase gamma subunit	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,POR
PNCOCPKN_03869	203119.Cthe_3129	1.01e-139	409.0	COG1055@1|root,COG1055@2|Bacteria,1TQCH@1239|Firmicutes,25CD7@186801|Clostridia,3WGPH@541000|Ruminococcaceae	186801|Clostridia	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
PNCOCPKN_03870	585394.RHOM_00325	1.23e-129	377.0	COG0697@1|root,COG0697@2|Bacteria,1V1H0@1239|Firmicutes,24BBW@186801|Clostridia	186801|Clostridia	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PNCOCPKN_03871	585394.RHOM_00355	4.48e-143	409.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
PNCOCPKN_03872	622312.ROSEINA2194_04393	8.74e-112	335.0	COG2267@1|root,COG2267@2|Bacteria,1V2IH@1239|Firmicutes,24BN4@186801|Clostridia	186801|Clostridia	I	Alpha beta	-	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
PNCOCPKN_03873	585394.RHOM_00365	4.43e-230	644.0	COG2270@1|root,COG2270@2|Bacteria,1TRTH@1239|Firmicutes,24AYI@186801|Clostridia	186801|Clostridia	S	Major Facilitator	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
PNCOCPKN_03874	585394.RHOM_00370	4.32e-110	322.0	COG2357@1|root,COG2357@2|Bacteria,1VDTE@1239|Firmicutes,24Q2S@186801|Clostridia	186801|Clostridia	S	RelA SpoT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
PNCOCPKN_03875	411463.EUBVEN_01388	8.83e-301	845.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia,25UWP@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk1	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
PNCOCPKN_03876	622312.ROSEINA2194_04395	2.46e-139	404.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia	186801|Clostridia	P	phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
PNCOCPKN_03877	622312.ROSEINA2194_04397	8.2e-160	452.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia	186801|Clostridia	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
PNCOCPKN_03878	622312.ROSEINA2194_04398	2.41e-153	436.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,248C4@186801|Clostridia	186801|Clostridia	P	phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
PNCOCPKN_03879	622312.ROSEINA2194_04399	1.05e-170	477.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
PNCOCPKN_03880	585394.RHOM_00395	3.7e-116	337.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,24FTM@186801|Clostridia	186801|Clostridia	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
PNCOCPKN_03881	585394.RHOM_00400	0.0	901.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia	186801|Clostridia	P	Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
PNCOCPKN_03882	622312.ROSEINA2194_04402	8.01e-127	365.0	COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,24D6A@186801|Clostridia	186801|Clostridia	T	Response regulator receiver domain protein	phoB	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
PNCOCPKN_03883	585394.RHOM_00410	1.83e-216	608.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
PNCOCPKN_03884	585394.RHOM_00425	0.0	1633.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia	186801|Clostridia	L	snf2 family	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
PNCOCPKN_03885	1031288.AXAA01000008_gene1275	3.93e-11	65.1	COG3307@1|root,COG3307@2|Bacteria,1U3ZF@1239|Firmicutes,249D2@186801|Clostridia,36GJ6@31979|Clostridiaceae	186801|Clostridia	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
PNCOCPKN_03888	585394.RHOM_00435	3.72e-106	309.0	COG1971@1|root,COG1971@2|Bacteria,1V4QK@1239|Firmicutes,24FY0@186801|Clostridia	186801|Clostridia	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
PNCOCPKN_03889	585394.RHOM_00440	4.17e-153	438.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia	186801|Clostridia	P	K -dependent Na Ca exchanger family protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
PNCOCPKN_03890	585394.RHOM_00445	1.52e-50	163.0	2DPVJ@1|root,333JK@2|Bacteria,1VGI4@1239|Firmicutes,24R70@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DZR,zinc_ribbon_2
PNCOCPKN_03891	585394.RHOM_00450	6.12e-161	470.0	2A7KX@1|root,30WIW@2|Bacteria,1V536@1239|Firmicutes,24J38@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03892	622312.ROSEINA2194_01741	1.28e-103	304.0	COG2755@1|root,COG2755@2|Bacteria,1V3A9@1239|Firmicutes,24FYQ@186801|Clostridia	186801|Clostridia	E	COG2755 Lysophospholipase L1 and related esterases	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
PNCOCPKN_03894	1280698.AUJS01000028_gene2292	8.95e-102	298.0	COG1954@1|root,COG1954@2|Bacteria,1V4IE@1239|Firmicutes,24HDM@186801|Clostridia,27VYY@189330|Dorea	186801|Clostridia	K	Glycerol-3-phosphate responsive antiterminator	glpP	-	-	ko:K02443	-	-	-	-	ko00000,ko03000	-	-	-	G3P_antiterm
PNCOCPKN_03895	411462.DORLON_02611	0.0	989.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,27V84@189330|Dorea	186801|Clostridia	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
PNCOCPKN_03896	411462.DORLON_02610	3.47e-153	432.0	COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,248U5@186801|Clostridia	186801|Clostridia	G	Belongs to the MIP aquaporin (TC 1.A.8) family	glpF	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
PNCOCPKN_03897	411462.DORLON_02609	1.61e-298	820.0	COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,27V95@189330|Dorea	186801|Clostridia	S	BFD-like [2Fe-2S] binding domain	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
PNCOCPKN_03898	411462.DORLON_02608	1.3e-273	752.0	COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia,27UZQ@189330|Dorea	186801|Clostridia	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_3
PNCOCPKN_03899	411462.DORLON_02607	8.93e-64	196.0	COG3862@1|root,COG3862@2|Bacteria,1VA4U@1239|Firmicutes,24MN9@186801|Clostridia,27VRH@189330|Dorea	186801|Clostridia	S	Protein of unknown function (DUF1667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1667
PNCOCPKN_03900	1340434.AXVA01000004_gene2641	4.88e-06	57.8	COG1653@1|root,COG3757@1|root,COG4733@1|root,COG1653@2|Bacteria,COG3757@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	lyc	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.2.1.17,3.2.1.8	ko:K01181,ko:K01185,ko:K02027,ko:K07273,ko:K07451,ko:K17315,ko:K17318	ko02010,map02010	M00207,M00603,M00605	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02048	3.A.1.1,3.A.1.1.24,3.A.1.1.29,3.A.1.1.30,3.A.1.1.9	-	-	Glyco_hydro_25,LysM,Phage-tail_3
PNCOCPKN_03902	585394.RHOM_00480	0.0	1201.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
PNCOCPKN_03903	585394.RHOM_00485	1.01e-126	382.0	2A7KX@1|root,30WIW@2|Bacteria,1V536@1239|Firmicutes,24J38@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03904	585394.RHOM_00490	2e-44	159.0	2ANQY@1|root,31DQM@2|Bacteria,1V7FM@1239|Firmicutes,24MF6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03905	1235800.C819_00145	3.9e-07	58.5	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,27IZH@186928|unclassified Lachnospiraceae	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
PNCOCPKN_03907	622312.ROSEINA2194_00904	3.72e-149	424.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia	186801|Clostridia	L	hydrolase, TatD family	ycfH	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
PNCOCPKN_03908	622312.ROSEINA2194_00905	2.22e-118	347.0	2DBGV@1|root,2Z969@2|Bacteria,1UI0Y@1239|Firmicutes,25E9X@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4130
PNCOCPKN_03909	622312.ROSEINA2194_00906	8.26e-275	757.0	COG4277@1|root,COG4277@2|Bacteria,1TRT2@1239|Firmicutes,247UD@186801|Clostridia	186801|Clostridia	S	DNA modification repair radical SAM protein	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3,Radical_SAM
PNCOCPKN_03910	642492.Clole_3044	8.46e-140	432.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
PNCOCPKN_03912	585394.RHOM_00540	1.7e-185	518.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
PNCOCPKN_03914	585394.RHOM_00550	1.48e-71	231.0	COG2385@1|root,COG2385@2|Bacteria,1TQSI@1239|Firmicutes,249H0@186801|Clostridia	186801|Clostridia	D	stage II sporulation protein D	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
PNCOCPKN_03915	622312.ROSEINA2194_00437	5.41e-90	274.0	COG0739@1|root,COG0739@2|Bacteria,1VATR@1239|Firmicutes,24N76@186801|Clostridia	186801|Clostridia	M	COG COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
PNCOCPKN_03916	585394.RHOM_00560	2.56e-201	578.0	COG0457@1|root,COG2199@1|root,COG0457@2|Bacteria,COG3706@2|Bacteria,1TS77@1239|Firmicutes,24E4N@186801|Clostridia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,sCache_3_3
PNCOCPKN_03917	585394.RHOM_00565	0.0	963.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia	186801|Clostridia	L	Belongs to the DEAD box helicase family	cshA	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
PNCOCPKN_03918	585394.RHOM_13945	2.48e-263	728.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PNCOCPKN_03919	585394.RHOM_00590	2.5e-141	401.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia	186801|Clostridia	KT	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PNCOCPKN_03920	397291.C804_00768	1.9e-181	551.0	COG0642@1|root,COG2205@2|Bacteria,1TP73@1239|Firmicutes,248Y6@186801|Clostridia,27ICQ@186928|unclassified Lachnospiraceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PNCOCPKN_03921	585394.RHOM_14445	3.46e-66	204.0	2DM5I@1|root,31T37@2|Bacteria,1V6J6@1239|Firmicutes,24K9S@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	SseB
PNCOCPKN_03922	585394.RHOM_14420	1.44e-122	350.0	COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia	186801|Clostridia	C	Psort location Cytoplasmic, score	rbr3A	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
PNCOCPKN_03923	585394.RHOM_14415	7.6e-76	228.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,24JS4@186801|Clostridia	186801|Clostridia	P	Belongs to the Fur family	perR	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
PNCOCPKN_03924	585394.RHOM_13060	3.38e-95	306.0	COG2199@1|root,COG2199@2|Bacteria,1V0N3@1239|Firmicutes,24FMU@186801|Clostridia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GGDEF,SBP_bac_3
PNCOCPKN_03925	622312.ROSEINA2194_01957	2.13e-92	285.0	2BZEU@1|root,30VT8@2|Bacteria,1V54M@1239|Firmicutes,24SSI@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03926	585394.RHOM_14405	1.02e-76	235.0	COG1670@1|root,COG1670@2|Bacteria,1V1ZC@1239|Firmicutes,249K2@186801|Clostridia	186801|Clostridia	J	Acetyltransferase GNAT family	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
PNCOCPKN_03927	585394.RHOM_14400	1.41e-97	285.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,24JM2@186801|Clostridia	186801|Clostridia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
PNCOCPKN_03928	1235790.C805_03317	2.21e-29	112.0	2E5GB@1|root,33080@2|Bacteria,1VF18@1239|Firmicutes,24R5R@186801|Clostridia,25XG3@186806|Eubacteriaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	CorC_HlyC
PNCOCPKN_03929	585394.RHOM_14390	2.66e-223	617.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia	186801|Clostridia	C	phosphate acetyltransferase	pta	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
PNCOCPKN_03930	585394.RHOM_14385	2.44e-255	708.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PNCOCPKN_03931	1280698.AUJS01000024_gene1511	2.99e-158	452.0	COG1102@1|root,COG1102@2|Bacteria,1TSIF@1239|Firmicutes,24BT4@186801|Clostridia,27UXV@189330|Dorea	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
PNCOCPKN_03932	457412.RSAG_02477	1.54e-270	751.0	COG1055@1|root,COG1055@2|Bacteria,1TT1V@1239|Firmicutes,24ART@186801|Clostridia	186801|Clostridia	P	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
PNCOCPKN_03934	585394.RHOM_14345	1.31e-245	676.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
PNCOCPKN_03935	622312.ROSEINA2194_00449	1.11e-315	867.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia	186801|Clostridia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
PNCOCPKN_03936	585394.RHOM_14335	1.71e-47	155.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia	186801|Clostridia	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
PNCOCPKN_03937	622312.ROSEINA2194_04436	5.69e-162	456.0	28P0Q@1|root,2ZBX8@2|Bacteria,1V22P@1239|Firmicutes,248XV@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03938	397288.C806_01154	3.64e-90	269.0	COG0582@1|root,COG0582@2|Bacteria,1V2RX@1239|Firmicutes,24DD0@186801|Clostridia,27QUG@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
PNCOCPKN_03939	622312.ROSEINA2194_00548	4.4e-33	117.0	2ENS3@1|root,33GD8@2|Bacteria,1VQH1@1239|Firmicutes,24VFX@186801|Clostridia	186801|Clostridia	S	Global regulator protein family	-	-	-	-	-	-	-	-	-	-	-	-	CsrA
PNCOCPKN_03940	515620.EUBELI_00422	7.06e-130	395.0	COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,25VSN@186806|Eubacteriaceae	186801|Clostridia	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
PNCOCPKN_03941	397287.C807_02862	6.35e-66	222.0	COG0727@1|root,COG0727@2|Bacteria,1TSB6@1239|Firmicutes,24AQ9@186801|Clostridia,27ND9@186928|unclassified Lachnospiraceae	186801|Clostridia	S	N-methylation of lysine residues in flagellin K00599	fliB	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	CxxCxxCC
PNCOCPKN_03942	97138.C820_01583	2.7e-53	184.0	COG5464@1|root,COG5464@2|Bacteria,1UI9X@1239|Firmicutes,25EEV@186801|Clostridia,36UNA@31979|Clostridiaceae	186801|Clostridia	S	Putative transposase, YhgA-like	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03943	1256908.HMPREF0373_01583	3.15e-51	162.0	2DZI1@1|root,32VB8@2|Bacteria,1VAA5@1239|Firmicutes,24MWS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FYDLN_acid
PNCOCPKN_03944	411463.EUBVEN_02075	2.76e-94	278.0	COG0406@1|root,COG0406@2|Bacteria,1V25J@1239|Firmicutes,24FZT@186801|Clostridia,25W5C@186806|Eubacteriaceae	186801|Clostridia	G	Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
PNCOCPKN_03945	622312.ROSEINA2194_00271	2.21e-124	358.0	COG2176@1|root,COG2176@2|Bacteria,1TRS5@1239|Firmicutes,24ER5@186801|Clostridia	186801|Clostridia	L	EXOIII	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	BRCT,RNase_T,zf-C4_Topoisom
PNCOCPKN_03946	140626.JHWB01000022_gene2109	3.94e-31	110.0	2ERQJ@1|root,33J9V@2|Bacteria,1VQ8Z@1239|Firmicutes,24VCG@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03947	585394.RHOM_14945	8.32e-29	103.0	2E7J1@1|root,3321A@2|Bacteria,1VFYW@1239|Firmicutes,24RBB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03948	1280679.ATVX01000017_gene218	2.05e-36	125.0	COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,24QXB@186801|Clostridia,4BZS5@830|Butyrivibrio	186801|Clostridia	C	Acylphosphatase	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
PNCOCPKN_03949	658088.HMPREF0987_02094	1.74e-145	422.0	COG2169@1|root,COG2169@2|Bacteria,1VC5Z@1239|Firmicutes,24I65@186801|Clostridia,27N4N@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
PNCOCPKN_03950	658088.HMPREF0987_02093	1.68e-248	691.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,27IIX@186928|unclassified Lachnospiraceae	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
PNCOCPKN_03951	658088.HMPREF0987_02092	0.0	1103.0	COG3250@1|root,COG3250@2|Bacteria,1TPK7@1239|Firmicutes,247VE@186801|Clostridia,27J10@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Domain of unknown function (DUF4982)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
PNCOCPKN_03952	888832.HMPREF9420_0119	2.2e-35	123.0	COG4545@1|root,COG4545@2|Bacteria,4P47F@976|Bacteroidetes,2FU4N@200643|Bacteroidia	976|Bacteroidetes	O	Glutaredoxin-related protein	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
PNCOCPKN_03953	743719.PaelaDRAFT_3926	2.66e-112	350.0	COG1409@1|root,COG1409@2|Bacteria,1VRCN@1239|Firmicutes	1239|Firmicutes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
PNCOCPKN_03954	1226325.HMPREF1548_03034	9.61e-38	141.0	2C2T8@1|root,32RB0@2|Bacteria,1V8YX@1239|Firmicutes,24M80@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03955	1408306.JHXX01000003_gene1416	3.16e-126	360.0	COG2316@1|root,COG2316@2|Bacteria,1TSF7@1239|Firmicutes,24A1B@186801|Clostridia,4BY0F@830|Butyrivibrio	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
PNCOCPKN_03956	742765.HMPREF9457_00412	5.72e-86	266.0	COG0834@1|root,COG0834@2|Bacteria,1VTCR@1239|Firmicutes,24YIS@186801|Clostridia,27WVQ@189330|Dorea	186801|Clostridia	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
PNCOCPKN_03957	742765.HMPREF9457_00411	7.19e-148	468.0	COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,27WC0@189330|Dorea	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,SBP_bac_3
PNCOCPKN_03958	585394.RHOM_14380	1.04e-173	488.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,24BGW@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
PNCOCPKN_03959	622312.ROSEINA2194_01965	2.94e-251	694.0	COG4284@1|root,COG4284@2|Bacteria,1TQUD@1239|Firmicutes,24A8D@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	2.7.7.23,2.7.7.83	ko:K00972	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00361,M00362	R00416	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
PNCOCPKN_03960	585394.RHOM_14370	6.25e-134	384.0	COG2357@1|root,COG2357@2|Bacteria	2|Bacteria	S	guanosine tetraphosphate metabolic process	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
PNCOCPKN_03963	457421.CBFG_05476	2.62e-59	191.0	2BYWB@1|root,32SGE@2|Bacteria,1VAZ2@1239|Firmicutes,24J86@186801|Clostridia,269B4@186813|unclassified Clostridiales	186801|Clostridia	S	Protein of unknown function (DUF3793)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3793
PNCOCPKN_03964	411469.EUBHAL_03045	4.2e-68	209.0	COG0716@1|root,COG0716@2|Bacteria,1V6D7@1239|Firmicutes,24J7W@186801|Clostridia,25WIN@186806|Eubacteriaceae	186801|Clostridia	C	flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1
PNCOCPKN_03965	936574.HMPREF1508_1331	7.94e-41	135.0	2E4DC@1|root,32Z8R@2|Bacteria,1VF6A@1239|Firmicutes,24QX7@186801|Clostridia	186801|Clostridia	S	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	ko:K19165	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
PNCOCPKN_03966	1410628.JNKS01000004_gene2041	2.32e-72	218.0	COG3654@1|root,COG3654@2|Bacteria,1V6EG@1239|Firmicutes,24J85@186801|Clostridia,27NM5@186928|unclassified Lachnospiraceae	186801|Clostridia	S	TIGRFAM death-on-curing family protein	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
PNCOCPKN_03967	622312.ROSEINA2194_02915	3.68e-246	684.0	COG0534@1|root,COG0534@2|Bacteria,1TP6V@1239|Firmicutes,248EF@186801|Clostridia	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PNCOCPKN_03968	622312.ROSEINA2194_00445	9.87e-54	171.0	COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,24QRR@186801|Clostridia	186801|Clostridia	S	PFAM Uncharacterised BCR, COG1937	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
PNCOCPKN_03969	622312.ROSEINA2194_00446	0.0	1224.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	actP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
PNCOCPKN_03970	180332.JTGN01000005_gene2749	3.05e-19	79.0	2EIM1@1|root,33CCB@2|Bacteria,1VM79@1239|Firmicutes,24UNI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03971	622312.ROSEINA2194_04435	4.57e-130	371.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
PNCOCPKN_03972	585394.RHOM_14320	4.31e-193	536.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia	186801|Clostridia	G	Transketolase, thiamine diphosphate binding domain	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
PNCOCPKN_03973	622312.ROSEINA2194_04433	1.06e-206	573.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia	186801|Clostridia	G	Transketolase	tktB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
PNCOCPKN_03974	622312.ROSEINA2194_04432	1.24e-106	333.0	COG1652@1|root,COG1652@2|Bacteria,1UIP6@1239|Firmicutes,25EPX@186801|Clostridia	186801|Clostridia	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
PNCOCPKN_03975	585394.RHOM_14305	2.84e-184	524.0	2C3W5@1|root,2ZBIU@2|Bacteria,1UZRE@1239|Firmicutes,24BHB@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PNCOCPKN_03976	622312.ROSEINA2194_04430	1.61e-63	205.0	2DMJ6@1|root,32RY3@2|Bacteria,1VBBI@1239|Firmicutes,24N5I@186801|Clostridia	186801|Clostridia	S	Colicin V production protein	-	-	-	-	-	-	-	-	-	-	-	-	Colicin_V
## 3601 queries scanned
## Total time (seconds): 497.8315920829773
## Rate: 7.23 q/s
