LOCUS       c00004_gnlPro..        24638 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LCELFIDJ_4.
ACCESSION   c00004_gnlPro..
VERSION     c00004_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 00:16:36
            Original ID  :: gnl|Prokka|LCELFIDJ_4
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 118107
            Orig. end    :: 142745
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24638
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[128107:132745]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14638
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24638
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24638
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(315..1310)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_Gly3P_dh_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_103"
                     /sec_met_domain="NAD_Gly3P_dh_N (E-value: 7.8e-33,
                     bitscore: 106.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLPGKIAIMGGGSWATALAKIVLSTQDSINWYMRRPDQVEEFLL
                     LGHNPSYLSAVKFDTDKIKFYTDINKVIKDSDTLIFATPSPFLKQHLMKVTTSMQDKFI
                     ISAIKGIVPDENMLVADYFAEYYNVPIDNIAVIGGPCHAEEIALERLSYITLACPNIEN
                     ARAFSSVFKNQYLNNSCCKDVTGIEYASVLKNVYAIVAGICHGMKYGDNFLAVFICNAI
                     EEMRNFLNAVHGLERDVTDSVYLGDLLVTAYSRFSRNRTFGTMIGKGYSVKIAQLEMEM
                     IAEGYYGTKCIREINEKYKVNMPILDTLYSILYEKKSPTTAIRQLTETFK"
     CDS             complement(1321..3051)
                     /locus_tag="ctg4_104"
                     /transl_table=11
                     /translation="MNLLELSEQEIIRRNSMEQLRQMGIEPYPAAEYVTNAFSKEIKEN
                     FKDDAEPRPVSIAGRIMSRRIMGKASFMELQDSEGRIQVYISRDDICPEENKDLYNIVF
                     KKLLDIGDFVGIKGFVFRTQMGEISVHAQEITVLSKSLKPLPVVKYKDGVAYDGFNDPE
                     LRYRQRYVDLVVNDGVKDIFMKRAAVIKTMRTALDEAGYTEVETPILQSIPGGASARPF
                     ITHHNSLDIDLYLRIATELYLKRLIVGGFEGVYEIGKNFRNEGMDRTHNPEFTCMELYV
                     QYKDYNWMMSFTEQLLERICIAVNGTCESVVDGKTINFKAPYRRLPILDAIKEKTGYDL
                     NGKSEDEIRTICKDLNLEIDETMGKGKLIDEIFGEFCEGTFIQPTFIIDYPVEMSPLTK
                     MHRSKPGLTERFELMINGKEVANAYSELNDPIDQEERFKEQLRLSEKGDDEAMFIDQDF
                     LRALQFGMPPTSGIGIGIDRLVMLMTGQTTIQEVLLFPQMRPEKTVKKDTADKYVALGI
                     DEAWVPALHKAGYLTTDTLVDANPNKLRQELCEMNKKYKLELQNPTAEEVEAWIAGAAK
                     "
     CDS             complement(3142..3753)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_105"
                     /sec_met_domain="CTP_transf_like (E-value: 2.2e-24,
                     bitscore: 79.4, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VETGLKENTVSKRKTGIYSGSFNPVHIGHLALANWLCEFTELDEL
                     WFLITPHNPLKEKEELMDDRLRYELVKKSIAGYPKFHASDFEFSLPQPTYTINTLRTLE
                     ASYPDREFYFIMGADNWKYITRWVEYEAIISNYPIFIYPRKGFDVEIPAQYPHIKKVDA
                     PLVEISSTFIREAFKTGKDVRFFLPEAIRNLPFPLQNNTF"
     CDS             complement(3738..3911)
                     /locus_tag="ctg4_106"
                     /transl_table=11
                     /translation="MNGKKLSKKWLYTFIGIAFVALATCTAALYYKEYIIATGTGLVFG
                     AQVINIIKWKRD"
     CDS             complement(3908..4477)
                     /locus_tag="ctg4_107"
                     /transl_table=11
                     /translation="MAGKLIIFSAPSGSGKSTIINFLLKQNLNLHFSISATSRAPRGTE
                     KDGVEYYFLTPDEFRARIAAGDFLEYEEVYTDKYYGTLKSEVERRLMSGDNVIFDVDVV
                     GGCNIKKFYGDRALSVFIQPPSIEDLRSRLEGRGTDAPEVIESRIAKAEFELGFADKFD
                     VIVVNDKLEVAQKEALKVIKEFLKKA"
     CDS             complement(4487..5347)
                     /locus_tag="ctg4_108"
                     /transl_table=11
                     /translation="MTGFGKVTAELPSKKVTVEIKALNSKQLDLSTRIPSIYKEKEMQI
                     RSLLLQSLERGKVEFNIFVEYIGKDTPTQINLAAVENYYNQIKDIADRLNIGLPADWFQ
                     TLLRMPDVIKTEAQEVNEEEWNVVEKAIKEAIGHLCDFRIQEGAMLQKLFEQKIANISR
                     LLSEVEQYEKERIEKIKARIMDNLEKIAGQDYDKNRFEQEMIYYIEKLDVNEEKNRLDN
                     HLKYYISTMESGHGQGKKLGFIAQEMGREINTLGSKSNHAEMQKLVVQMKDELEQIKEQ
                     VLNVL"
     CDS             5583..6302
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_109"
                     /sec_met_domain="Peptidase_M22 (E-value: 1.4e-23, bitscore:
                     76.9, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSCILNIETSTSVCSVALSMDGEVLFAKASFDGPSHAALLGVFVE
                     EALSVLKKKGKKALDAVAVSSGPGSYTGLRIGVSVAKGLCFGFGIPLIGIHTLDIMAAT
                     VNSKGDSQIVSITDDCLYCAMLDARRMEVYAAIYDASLKPVRETKADIVEAGTYASYLE
                     KGKVCFFGNGASKCKSVITSPNAIFIEDIHPLAVNMIPLSEQAFAAGKFEDTAYFEPFY
                     LKEFQATVAKNKVLLAR"
     CDS             complement(6448..6558)
                     /locus_tag="ctg4_110"
                     /transl_table=11
                     /translation="MIVGFKKNRMYIIGGCLQQLIYIACRRKTYMDGNPK"
     CDS             6905..7291
                     /locus_tag="ctg4_111"
                     /transl_table=11
                     /translation="MAHYYVVRQKLDKTGAEDKVRYYGVPVTCGRVSTKKLADLVADRC
                     SLSRGDVFASVCEIGGMILELLKDGYSVELDGLGDFYLSAGSEGFEDPKKCTPHRVKAR
                     RVCFRMAPCVRKSMKFVKFERNPW"
     CDS             7291..9381
                     /locus_tag="ctg4_112"
                     /transl_table=11
                     /translation="MQITYYRHKKGVLRMHSRDMEYIVGLLKNGKDAEAILSVRRKLNM
                     AFLARTTDLSGKLPVLAFGSTFKKNGDGIQLRRYNGYVLLEVNGLESQSEAEAVRREAA
                     ALPQTLLAFVGLSGRSVKIVVPFVLPDGSLPKKEEQARMFHAAAYQLAVRHYQPQLGSI
                     ISLKEPFLSRGCRMSVDPDAYYNPDAVAIRIEQPLQMPDGGDLKIVPSPVRDPLEMMAP
                     GADRNGQIATLFSVILMEMTRRFSESPEDDIQLLFIDLAQACCRLGIPEEEAVGWTLRY
                     EALKKYKIDIRMAFRTAYTLENVSNRAEPLSSVPPSMSLVLRLDEFMNRRYFFRTNEMS
                     GGVEYLDRSMIQFVYKPYTTKVRNSICLEAQQEGLNVWDKDIDRYVNSDRVPIYHPIDH
                     FLGNLPAWDGKERIRALAGRVPCDNPVWGDLFYRWFLSMVAHWMELDSEHGNSTTPLLV
                     GGQGCGKSTFCLNLLPPVLRPYYTDSIDFGNRRGAELALHRYALINIDEFDSVRSSHQS
                     FLKHILQKAVVNTRLPYQSASRNLRRYATFIATSNNYDLLTDPTGSRRFICVEVKGRID
                     YAQPIDYDQLYAEAKELLRRGERFWFTPEEEALITENNRDFQQQPAEEQLFLRYFKIAE
                     DIEEAKPLLASEILDMIAEKQPGFNITKTMILNFGKLLKRNSVPNKRTMRGTCYYVEEV
                     DG"
     CDS             9662..9808
                     /locus_tag="ctg4_113"
                     /transl_table=11
                     /translation="MRRKNTNVLLVFGVVIAIILLMIWLFLGTTLEQEANPETDPMTVE
                     QNI"
     CDS             complement(10001..11197)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_114"
                     /sec_met_domain="OAD_beta (E-value: 1.5e-152, bitscore:
                     500.6, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGSVLLQAAGTAHESFLQFLGENLELFLTYTGVYNATPGHLIMI
                     LVGLLFIFLAIKYEFEPMLLIPIGFGILIGNIPFKDAGLQVGIYEQGSVLNILYQGVTS
                     GWYPPLIFLGIGAMTDFSALISNPKLMLIGAAAQFGIFGAYIIALQMGFEPNQAGAIGI
                     IGGADGPTAIFLSSKLAPNLMGAIAVSAYSYMALVPIIQPPFMRLLTTQKERLIRMKPP
                     RAVSSTEKIVFPIVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLAETARGPLIDT
                     ITILLGITVGASTQATQFLTLNSIKIFGLGALSFVIATCAGILFVKFFNLFLKEGNKIN
                     PLIGNSGVSAVPDSARISQNVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLG"
     CDS             complement(11202..11633)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 65.5; E-value:
                     9.6e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_115"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2e-20, bitscore:
                     65.5, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSFKYTINGNVYKVHISSVVDDIAEVEVNGTPYQVKMEKPAKKQ
                     MVTLKRPAQAPTTASGEPVISRPAASTTKGAVKSPLPGVILQVNCKVGDTVKRGQNLLV
                     LEAMKMENNINADRDGKIIEIKVNKGDSVLEGADLVVIG"
     CDS             complement(11656..12549)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_116"
                     /sec_met_domain="OAD_gamma (E-value: 1.1e-11, bitscore:
                     38.3, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNMINKKIGVLLLFALLVSFGAKAQRATSMRINEVLVINEDNFVD
                     DYGKRHAWIELFNNSAGSVNIAGCYLTNDKSNPKKYPIPKGDVLTVIPPRQHTLFWADG
                     EPDRGTFHVNFTLDPSKENYIALYDADGKTLIDEIVIPASQKADVSYGRTLDGQGEWTA
                     LTKVTPSTNNVTLDSNEKIENFKENDSWGIGMTLTAMAVVFSGLFLLFIIFKQIGKLSI
                     AASKRNAQKAAGAAVIADNAGQESGEIFAAIGAALYEMSDDNHDIEHTVLTIRKVQRSY
                     SPWSSKIYGLREVPKK"
     CDS             complement(12565..14118)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_117"
                     /sec_met_domain="CT_Btheta (E-value: 1.5e-291, bitscore:
                     960.0, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIALRETARLGGGEKRIESQHKKGKYTARERIAML
                     LDEGSFEEFDMFVQHRCTNFGIEKTKYLGDGIVTGYGTIDGRLVYIYAQDFTVFGGALS
                     EALAMKICKVMDQAMKMGAPVIGLNDSGGARIQEGVNALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFNIMTRGTSYMFLTGPKVVKTVTGEDVTQEQLGGASVHTT
                     KSGVAHFAVDTEEDGLQLIRKLISFLPQNNLEETPLIECKDPIDRLDDNLNDIIPDNPN
                     QAYDMYEVIGTIIDNGEFLEVHADYAKNIIVGFARFNGQTVGIVANQPKVMAGCLDSNA
                     SRKAGRFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTV
                     TLRKSYGGAYCVMSSKHLRGDMNYAWPTAEIAVMGPSGAVEVIFAKEVAASEDPKACAA
                     EKEAEYKKAFANPYNAAQYGYIDDVIEPRNTRFRIIRALQQLQTKKLSNPAKKHDNLPL
                     "
     CDS             complement(14231..14638)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_118"
                     /sec_met_domain="Glyoxalase_4 (E-value: 1.5e-26, bitscore:
                     85.9, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTHIEHLGIAVKSIEACLPYYEEVLGLKCYNIEEVADQKVKTA
                     FFKVGQTKIELLEPTSEDSTIAKFIEKKGEGIHHIAFAVPDVQAALDEAESKGVKLIDK
                     APRGGAEGLNIAFLHPKSTCSVLTELCMPGK"
     CDS             complement(14783..17188)
                     /locus_tag="ctg4_119"
                     /transl_table=11
                     /translation="MKIRAIATLLFILFSISAFGQGRAKISGYIRDADGNPLDLVNIRV
                     KNTLNGTMSNEKGHYSLSVATGDSVTLIYSCLGYNKAERILPQVTKDMRLNVQMNYTSL
                     ELGEVVATAIRKQTTTLETLNADRVKLLPDPAGGSIESLVVTFAGVTSNNELSSQYSVR
                     GGSYDENIVYVNGLEVFRPLLIRSGQQEGLSFINPDMTEAVNFSAGGFEARYGDKMSSV
                     LDITYKKPKGFEGSASASLLGANAYVGSSSGKFTQVTGFRYKTGRSLLKTTDTDAEYDP
                     NFIDLQTYMTYQLAPKWEINFLGNLAINNYKFIPHTRETSFGTATNAKKFKVFMSGQER
                     DKFETLFGALTLKHNLNDNTELGLQASAFTSKEEEGYDIAGDYWLGDAAEEGGGEIQKL
                     SIARYNEHARNRLHSNIMNVGHYGVARIKNNTLKWGATVQLEKINDKISEWEKRDSAGY
                     SLPQGGGNVNVIANLFSDNKLESTRISGYLQDVFKFRTKQGLFTLVGGVRGSYWSYNRE
                     FIFSPRASIGFIPNFDQNLTFRLASGLYYQSPFYKELRTTVQDEHGNSIIQLNKNLKSQ
                     RSIHVIAGGDYTFRASGRNFKVSADMYYKKLDNLNPYTVDNVKIRYYGENCAQGHAMGL
                     DVKFFGEFVPGTDSWISFSLMKAEQSIRGSEYVPMPNSQGYNVSLFFQDYFPGYKRVKL
                     NLKGVLSGGLPVTAPRTGYEDGYFRTPTYKRVDLGFSYQLAGGTDAIMDRGFFRNLKNI
                     WLGLDIFNLFDIKNTSSYYWITNIDNHQYAIPNYLTGRQLNIRLIVDF"
     CDS             17297..18229
                     /locus_tag="ctg4_120"
                     /transl_table=11
                     /translation="MPLNLQKNLPAVELLKKEHIFVMDSLRASEQDIRPLRVVVLNLMP
                     LKITTETDLVRLLSNTPLQVELDFMKIKGHTPKNTPIEHMKEFYKDFDEMQDDFYDGMI
                     ITGAPVEQMPFEEVNYWEEVTEIFDWARTHVTSTLYICWAAQAGLYHFYGVPKYDLPAK
                     MFGVFRHTLREPYVPIFRGFDDEFYVPHSRHTEIRREDVMKVPDLTLLSESEESGVYMA
                     MARGGREFFITGHSEYSPYTLNDEYMRDVNKGLPIAVPRNYYRNNNPALGPVVRWRGHA
                     NLLFTNWLNYYVYQETPFRIEDISKLGNL"
     CDS             18252..20081
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_121"
                     /sec_met_domain="Peptidase_U32 (E-value: 2.4e-73, bitscore:
                     239.1, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTKSRPIELLSPAKDLNCGIEAINHGADAVYIGAPKFGARSAAG
                     NSLEDIRELCEYAHLYGARIYVTLNTILKEDELEEAERMIWDLWRVGTDALIIQDMGIT
                     RLNLPPIPLHASTQTDNRTPEKVRFLEAAGFTQVVLARELSLNEIRRISEATTVPLEVF
                     VHGALCVSYSGQCYLSAALSGRSANRGECAQYCRLPYTMVDATGTEIVTHKHLLSLKDM
                     NRSDQLEALLDAGVSSLKIEGRLKDAGYVKNITAYYRKKLDAVLSRRPEYRRASAGRST
                     YTFEPVAEKSFNRGFTPFLLEGRTADITAFNTPKSLGEPVGTVKEIKGNSFTVAGLKQL
                     NNGDGLVFFNRKGELEGFRVNRVEANRVFPLDMPQLAPKTPLYRNFDQAFDKLLAKPSA
                     ERKLSLEIEFLDNPFGFTLCMEDETGARIMLTEPFAKELARREQQDNIRTQLSKLGNTP
                     FEASEVVVGLSENWFVPSSLLADMRRRGVEKLLEARRARYPRETVKRVQPSVSIPFPER
                     QLTYLGNVANGKARSFYQDHGVEQIDPAFELSPRKDVPLMFTKHCLRYSMGWCPTYQKD
                     KSPYKEPYYLLYKDTRLRLQFDCKHCQMLVFES"
     CDS             complement(20321..20788)
                     /locus_tag="ctg4_122"
                     /transl_table=11
                     /translation="MKIINEALLDETTGRAKQSPRLRMNYNFHEHLDDPVNRLLNALEP
                     GTYLRPHRHLNPKKDEIFLLLRGRIAVFLFDNKGEITQTQILDPKEGVYGAEIKAGTWH
                     GLLVLESGSVIYEIKEGPFAPLAPENFAPWSPAPEDTKGVAKYMELLGKAI"
     CDS             20885..23617
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_123"
                     /sec_met_domain="Peripla_BP_1 (E-value: 3.6e-07, bitscore:
                     22.9, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPALTYYALLVLLLASCFSCKTDSEKKKFVIGVSQCTLEGSWRK
                     SMLLDMKVQASEYPGVSLLVEDAADSSLLQVEQIRSLIKRKVDLLIISANESEPVTPIA
                     IEAYRAGIPTILVDRKISSDEYTTYIGGNNYEIGRQAGFFVNRQVKEKYPTVLEVWGLS
                     GSSPAQDRHRGFMEVLNSRIKVKEIFGKWKPETVEKEIAEMDSLEEVDVVFAHNDVMAM
                     AARRAIERMHPGLADRISFVGIDAVSGRGSGLEAVMHGELAASVLYPTGGSLAIRVAMQ
                     ILNGEDVSRQYLLSSALIDKNNAGTLFIQSEQVVDYQHQIELQRENLESMLSKYTFLQN
                     SVGIILLLMGMLLLSALYVVHVNRAVKRKNRELKRTNLQVQQQKEELAEANRYIEKSTA
                     QKLQFFTNITHEIKTPLTLILGPLGKLSKEAPEGSSLADDIRIIRKNAERLKRVVDQLL
                     DFRKVESNKMNMRVGEVDLVAFVAEVKSYFDTMAATKQIHFTFEHDCPSVNIWVDRDKM
                     EKILANLLSNAFKFTLDGGTVTIRLKDKGDQVELSVEDNGKGIPSENIASVFDRFFTGD
                     QNYVTGTGIGLHLTREFVHMHKGTIRVESVPHKSTVFTVILLKGKSHFDESCIFDLSVT
                     ELSSGVADLNTDELQEVLNRTYNYTVLVVEDDLDIQSYLQAELKQNFRVLVADNGVKAL
                     EVLMNEEISMVISDVMMPEMNGFDLCRKIKSDIVLSHLPVMLLTALSDDKQQMYGAASG
                     ADAYIQKPFNIEVVKLRIIKLLEDRVRLREAYARDASSPAVSVKEEKAGSMDDLFMNRF
                     LKLIEESYADPDFSIEKGSEKLGLSRVHLYRKVKELAGVTPTDFLRNYRLKKAAALLRR
                     KAGNVNEVAYATGFGSPAYFSKCFKAVYNITPTEYLEKE"
ORIGIN
        1 accagtcgaa gctattgttt aatgcttcta ccactgcttt tgttcctaaa tagctgccgc
       61 cgataccgat ggcgacaaca acttcacatt tggaacgaag tacgttagct gtattttcga
      121 tgtctgtcag ttcagcatct gtaatagaag aggggaggtg caaccaacct aaaaagtcgt
      181 tacctgcacc attaccattt tgtaaagtgg cattacattc gtgggccttt gcagcctgag
      241 catatacctg ttctttcgtt acggtaccca gcgctttgtc aatgttaaga ctgatgttct
      301 tcatatttac attattattt aaatgtttca gtcaactgcc gtatcgcggt agtcggcgat
      361 ttcttttcgt atagaatact atataaagta tccaagatcg gcatgtttac tttatatttt
      421 tcgtttatct cccgaataca ttttgtcccg taatatcctt cggcgatcat ctccatttcg
      481 agctgggcta ttttgacgga ataacctttc ccgatcatgg tcccgaacgt acggttccgg
      541 ctgaagcgag aatatgcggt taccagaaga tcaccgagat ataccgaatc tgtcacatcc
      601 cgttccaggc catgtacggc gttgaggaag ttacgcatct cttcgatcgc gttgcagatg
      661 aaaactgcca gaaaattatc tccgtacttc ataccgtggc agatacctgc gacgatagca
      721 tatacgtttt tcaatacgga agcatattca atacctgtaa catccttgca acaggagttg
      781 ttcagatact ggttcttaaa tacggaggag aaagctcttg cattctcgat attagggcaa
      841 gccagcgtga tataggacaa ccgttcgaga gcgatctctt cggcatggca cggaccgccg
      901 atgacagcga tattgtcaat cgggacattg tagtattcgg caaaataatc ggctacgagc
      961 atgttttcgt ccggaacgat tcctttgatg gccgaaatga tgaatttgtc ttgcatggag
     1021 gtcgtcacct tcatcaaatg ttgtttcaaa aaaggagaag gggtggcgaa aatcaaagtg
     1081 tccgaatctt tgattacttt gttgatatcc gtgtagaatt tgattttgtc agtatcaaat
     1141 ttgacggcgg aaagatagct ggggttatgt cccaacaaca gaaactcttc tacttggtct
     1201 ggccgacgca tataccagtt aatactatct tgtgtagaaa gtacaatctt ggccaaggcg
     1261 gtagcccagc taccacctcc cattattgca atttttccgg gcaacttcat agtattactc
     1321 ttatttggct gcgcctgcaa tccatgcctc tacttcttcg gcagtggggt tttgcaattc
     1381 cagtttgtat ttcttattca tttcgcagag ttcctgtctc agcttgttgg gattagcatc
     1441 taccaacgtg tcggttgtga gatatccggc tttatgtaaa gcaggaaccc atgcttcatc
     1501 gatacccagt gcgacatatt tgtctgcggt gtctttctta actgtctttt ccgggcgcat
     1561 ctgcgggaag agcaacactt cttgaatagt cgtttggcca gtcatcaaca tcaccagacg
     1621 gtcgatgccg ataccgatac cagacgtcgg aggcataccg aattgcagtg cacgcaaaaa
     1681 gtcctggtcg atgaacatcg cttcgtcatc ccctttttcg ctcaggcgca attgctcttt
     1741 gaagcgctct tcctgatcga tcggatcgtt cagctcacta taggcatttg ccacttcttt
     1801 accgttgatc atcaattcga aacgttcggt caatccaggt ttgctccggt gcatcttggt
     1861 tagcggactc atctcgaccg ggtagtcgat aatgaaagtc ggctggataa acgtgccttc
     1921 gcagaattca ccgaagattt catcgatcag cttgccttta cccattgttt catcgatttc
     1981 aaggttcaaa tccttgcaaa tcgtgcgtat ctcgtcttcg ctcttgccat tcaggtcgta
     2041 acctgtcttt tccttgatgg catccagaat cggcagacgg cggtaaggag ctttaaagtt
     2101 gatggtcttg ccgtcgacta cactttcaca tgtaccgttg acggcgatac agatacgttc
     2161 caacagctgt tcggtgaagc tcatcatcca gttgtagtcc ttatattgga cataaagttc
     2221 catacaggta aattccggat tgtgggtgcg atccatacct tcgttacgga agtttttacc
     2281 gatttcgtag acaccttcga aacctccgac gatcaatcgt ttcagataca gttcggtagc
     2341 aatacgcaga tagaggtcga tatccagcga gttatggtgc gtaatgaacg gacgtgcgct
     2401 tgctcctccg gggatggatt gcaggatcgg agtttctact tccgtatatc cagcttcgtc
     2461 cagggcggta cgcatggtct tgataactgc cgcacgtttc atgaaaatat cctttacgcc
     2521 atcattgacc accaggtcga catagcgttg gcgataacgc aattccggat cgttgaatcc
     2581 atcgtatgct acaccgtctt tgtatttgac gaccggtagc ggcttgagtg atttggataa
     2641 taccgttatc tcttgtgcat ggacggaaat ttcgcccatc tgtgtacgga atacgaaacc
     2701 tttgattccg acaaagtcgc cgatatcgag caatttcttg aaaacaatgt tatacagatc
     2761 tttattttct tccgggcaaa tgtcgtcacg agagatataa acctgtattc tgccttctga
     2821 atcctgcaat tccatgaagg aagcctttcc catgatgcgg cggctcatga tgcggccggc
     2881 aatacttacg gggcggggct ctgcatcgtc tttaaaattc tcttttatct ctttggaaaa
     2941 tgcattcgtt acatactcag ctgcgggata aggttctatc cccatctgac gtaactgctc
     3001 catgctgtta cgtcttatga tttcctgttc actcagttct aatagattca ttacgctatt
     3061 attttgtata atacggcgca aaaatacaaa acttttctta cttattgcct aaaaacgtat
     3121 gcgactttac gctttatgtt cttaaaaggt attgttttgt aatggaaaag gcagattacg
     3181 tatggcttcg ggcaggaaga agcggacatc ttttccggtc ttgaaagctt cgcgtataaa
     3241 ggttgaggat atttcgacca aaggggcgtc tacttttttt atgtgaggat attgtgccgg
     3301 aatttcaaca tcgaatcctt tacgcggata gatgaagatc ggataattgg aaatgatggc
     3361 ttcgtattct acccaccggg taatatattt ccaattgtcc gcacccatga tgaaatagaa
     3421 ttcacggtcc ggataacttg cttccaatgt ccggagtgtg ttgatggtat aagtgggttg
     3481 aggaagagaa aactcgaagt cactggcgtg gaacttaggg taaccagcga tggatttttt
     3541 taccagttca tagcgaagcc ggtcatccat cagttcttcc ttctctttta gcgggttatg
     3601 gggggtgatc agaaaccata gttcgtccaa ctccgtaaat tcacacaacc agttggctaa
     3661 tgccagatgg ccgatatgaa ccggattgaa tgaaccggaa taaatgccgg ttttacgttt
     3721 gctgaccgta ttttctttca gtcccgtttc cacttgatga tatttatgac ttgtgcaccg
     3781 aataccaatc cggtaccggt cgctatgata tactccttat aatatagggc ggctgtacaa
     3841 gtggcaagag cgacaaatgc tataccaatg aatgtatata gccatttctt ggataacttc
     3901 ttgccgttca tgctttttta aggaactctt ttatcacttt tagtgcttct ttttgtgcga
     3961 cttccagctt gtcgttcacc acgattacgt caaatttgtc ggcaaaaccc agttcaaatt
     4021 cggctttggc aatgcggctt tcgattactt ccggagcatc cgtaccgcgt ccttccagac
     4081 gactccgcaa atcttcgatc gaagggggct ggataaagac cgaaagagca cggtcgccat
     4141 aaaacttctt gatgttgcaa cctcctacga catcgacatc gaatatgacg ttatcgccac
     4201 tcatcagcct tcgttccacc tcgcttttca gcgtgccgta atatttgtcg gtatagacct
     4261 cttcgtattc caggaaatct cctgctgcta tacgggcacg gaattcatcc ggtgtaagga
     4321 aataatattc cactccgtcc ttttccgtac cacgtggggc ccggctggta gccgagatgg
     4381 aaaaatgcag gttcagattc tgcttcagca ggaaattgat gatagtggat ttgcccgaac
     4441 cggacggcgc ggagaatatg atcagtttgc cagccatata tcgtttttat aatacgttta
     4501 atacttgttc tttgatttgt tccagttcgt ctttcatctg gacgacaagt ttttgcatct
     4561 cggcatggtt gcttttcgaa ccaagggtgt tgatttcacg tcccatttcc tgggcgatga
     4621 aaccgagttt cttaccttgt ccgtgtccgc tctccatcgt gctgatgtaa tatttcaggt
     4681 ggttgtccag gcggttcttt tcctcgttta catccagttt ttcgatataa tagatcatct
     4741 cctgttcgaa ccggttcttg tcgtagtcct gtccggcaat cttttcgaga ttgtccatga
     4801 tacgggcttt gattttttcg atccgctcct tttcatactg ttctacttct gaaagcaggc
     4861 gggagatatt ggcaattttc tgttcgaaca acttttgtaa catggcgcct tcctgaatac
     4921 ggaaatcgca aaggtgccct atggcctctt tgatcgcttt ctcaaccaca ttccattcct
     4981 cttcgtttac ttcctgggcc tctgtcttga tcacgtccgg catgcggagc agggtctgga
     5041 accagtcggc gggaagtccg atgttcaggc ggtcggcaat atctttgatt tgattgtaat
     5101 agttttctac cgcagccaag ttgatctgtg tgggcgtgtc tttaccgata tattcgacaa
     5161 atatattaaa ttcgactttt ccacgttcaa gcgactggag taacaaactg cgtatttgca
     5221 tttctttttc tttgtagatg gaaggaatgc gggtcgacaa atccagttgc ttgctgttca
     5281 gagcttttat ttctacggtt acttttttag aaggaagttc ggctgtaacc ttaccgaatc
     5341 cagtcattga ttgtatcatt gttctaaaaa tttgtgcaaa gatagctaat caattgataa
     5401 ttgacaattg acgattgaca atataattga gaaaaagccg aaaccatccg tgtcagcctt
     5461 aataaaatcg gttttgatca tgagattaca gttatgtttt atacttttgc atccattatc
     5521 aaccgattgg cttttgacac atattttaat tgtcaattgt caattgtcaa ttgtcaatta
     5581 aaatgtcttg tatattaaat atcgaaacat cgacttctgt atgctctgta gcgttgtcta
     5641 tggatggtga agtccttttt gcgaaggcct cgttcgacgg cccttcgcat gcagccttat
     5701 taggcgtatt tgttgaagaa gctctttccg tattgaaaaa gaaggggaag aaagccttgg
     5761 atgccgtagc ggtcagtagc ggtcctggtt cttataccgg actccgtatc ggagtgtctg
     5821 tcgctaaagg tctttgcttt ggtttcggta ttcctctgat cggcattcat acgttggaca
     5881 tcatggctgc tactgtcaac agtaagggcg attcgcaaat cgtctctatt actgatgatt
     5941 gcctttattg tgctatgttg gatgcccggc gtatggaggt ttatgccgct atctacgatg
     6001 cttccttaaa gcctgtccgc gagacgaagg ccgatattgt ggaagccggt acgtatgctt
     6061 cttatctgga aaaagggaaa gtttgtttct ttggcaacgg tgcttccaaa tgcaaatcgg
     6121 tcatcacttc tccgaacgcc atctttatcg aggacatcca tcctcttgcc gtaaacatga
     6181 ttccgctctc ggaacaagct tttgccgccg gcaagtttga agacaccgcc tatttcgaac
     6241 cgttctacct gaaagagttc caggcgacgg ttgcaaaaaa taaggtgctt ttagctcgat
     6301 gatgtagttg tgtgctatgt cggaatggca cgtttgtcga aatttttatg taagtccggt
     6361 caatcggaaa agaacttaga tatgcaaaat cgtcctgttt cttgtgtttg atagctgtaa
     6421 tgtcaaacat ggaaacggga cgatgtgtta tttagggttg ccatccatgt aagtcttcct
     6481 cctgcaagca atataaataa gctgctgtaa acatccacct attatataca tacgattttt
     6541 tttaaatcca actatcatac tatcatattt acatataaat atctgtatat tagtttataa
     6601 aaatatgata gtatctattt tcaactatca tttcatacta tcatactatc atgtcgtata
     6661 tcacatgctt ctgtcttcgt gctggggaaa aataagtgta gatataattg aataaagtgc
     6721 tgtaaatatt tgtattatag atgttttatt tgtatatttg taataagaaa agaagcccgt
     6781 catccgggtg tcggaagggg tgagacccgg gtgttgatac cgttcagatg ggggtgtcaa
     6841 aagtgttaaa atgggcgtct tgagaagaat atctggttgt ttaatattaa aaatactgtt
     6901 atttatggca cattactatg tagtccggca aaaactggac aagacgggag cggaagataa
     6961 agtacgctat tatggtgttc cagttacgtg cgggcgggtt tcaacgaaaa agctggctga
     7021 tttggttgcc gatcgttgct cgttgagccg aggtgatgtg ttcgcttcgg tttgcgagat
     7081 cggagggatg attcttgaat tgttgaaaga cggctattcc gtggagttgg acgggttggg
     7141 tgatttttat ctttcggcag gaagtgaagg cttcgaagat ccgaaaaaat gtactcccca
     7201 tcgggtgaag gcgcgtcgtg tctgtttcag gatggctccc tgcgtgagaa agagtatgaa
     7261 atttgtcaaa ttcgaaagaa atccttggta atgcaaatca catattacag gcataaaaaa
     7321 ggcgtgttgc ggatgcactc gcgtgatatg gaatatattg tcgggttgct gaaaaacggc
     7381 aaagatgcgg aagcgatact gtcggttcgt cgaaaattga atatggcgtt tttggcacga
     7441 accacggatt tgtccggaaa actaccggtt ctggcttttg gctcgacgtt caagaagaat
     7501 ggcgatggaa tacagttgag gcgctataac gggtatgtct tgttggaagt gaacggcttg
     7561 gaaagccaga gtgaggcgga ggccgtccgc cgtgaagctg ccgccctgcc gcagaccttg
     7621 ctggcgttcg tcgggctgag cgggcgttcg gtcaagatcg tggttccttt tgtgctgccc
     7681 gacggctcgc tgccgaaaaa agaggagcag gcccgtatgt ttcatgctgc ggcttatcag
     7741 ctggcggtac ggcattacca gccgcagttg ggcagcatta tatcgttgaa agaaccgttc
     7801 ctgtcgcggg ggtgccggat gagtgtggat ccggacgcct attacaatcc ggatgcggtg
     7861 gcgatccgga tcgagcaacc tttgcagatg ccggacgggg gtgacttgaa gatcgtgcct
     7921 tctccggttc gggatccgtt ggagatgatg gctccgggag cggatcggaa cgggcagatc
     7981 gccacgctgt tcagtgttat cctgatggag atgacgcgtc ggttttcaga aagcccggaa
     8041 gatgatatcc aactgctgtt catcgacttg gcgcaggctt gctgccggct tggaataccg
     8101 gaggaagagg cggtgggctg gacattgcgc tatgaggctt tgaaaaaata taagatagac
     8161 atccgtatgg ctttccgtac ggcatatacg ttggagaatg tttcaaaccg tgcggagccg
     8221 ctctcttccg tcccgccatc catgtcgttg gtgttgcggt tggacgagtt tatgaaccgg
     8281 cgttatttct tccggacgaa tgagatgagc ggtggagtgg aatatttgga ccgttcgatg
     8341 atacagttcg tttacaagcc ttatacgacg aaagtccgga attccatttg cttggaagcc
     8401 cagcaggaag ggttgaatgt atgggacaag gatatcgacc gatatgtcaa ctccgatcgt
     8461 gttccgatat atcatcctat cgatcatttt cttgggaatc ttccggcttg ggacggaaaa
     8521 gaacgcatca gggcattagc cgggcgtgtc ccttgtgaca atccggtatg gggagatttg
     8581 ttttaccgct ggttcctaag catggtggca cattggatgg aactggattc ggaacacggg
     8641 aatagtacga cacctctgtt ggtcggtggc caagggtgtg ggaagtccac gttttgcttg
     8701 aatttgttgc caccagtgtt gcgtccttat tatacggaca gtatcgattt cggcaatcgc
     8761 cgtggggcgg agttggcttt gcaccggtat gcgttgatta atatcgatga atttgattca
     8821 gtgagaagtt ctcatcaaag ttttttgaag catatcctgc aaaaagcggt tgtgaacact
     8881 cgtttgcctt atcagagcgc gagccgtaac ttgcgtcgct atgccacgtt tatcgcgacc
     8941 agcaacaatt atgatttgct gacggatccg accggtagcc gccgtttcat ttgtgtggag
     9001 gtgaaggggc ggatcgatta tgcccagccg atcgattatg atcagttgta tgcggaagcg
     9061 aaagaattgt tgaggcgtgg tgaacgtttt tggtttactc cggaggaaga ggcgctgatc
     9121 actgaaaaca acagggattt ccagcagcag ccggctgaag agcaactgtt cctgcgttat
     9181 ttcaagatcg cggaggatat tgaagaggca aagccgcttc tggcgtccga gatactggat
     9241 atgatcgcgg agaaacaacc cggttttaac attacaaaaa cgatgatcct taatttcggc
     9301 aagcttttga agcggaatag cgtgccgaat aagcggacga tgagggggac ttgttattat
     9361 gtggaagagg tagatggttg atatataacc gattgactaa ttttatgtat gatggtatga
     9421 tagtagccat gacagttgtt ttgcgaactg tcatggctgt tttgtgttga tatatagtgg
     9481 gttattgcca attatgatgg tatgatagtt ggatcgtcta tttccaacta tatttgtaag
     9541 tgaagaaaaa acattctttc taaaatattt actcagttaa ataaagaaca aaagtaagga
     9601 acggttaaac caaaaaaggg ggtgtcttgt ttaatcttca aatcaatatt gaagaataga
     9661 catgagacga aagaatacga atgtactgct ggtctttggt gtggtgatcg cgattatcct
     9721 gttaatgatt tggttgtttt tggggacaac attggaacag gaggcaaatc cagagacaga
     9781 tccgatgacc gtcgaacaaa atatctgata aggtcggata taaaaaggga ggctgtgtcg
     9841 taaatagttt tttatgatac agccattaat atacttctga tgaatcgttg tgcgcatata
     9901 caaacttacc caagaatacg ttaaagtccg taaacttggg taagttttta tatttggaga
     9961 tgacttggag ttcagctcct ttttatgtag aataagtgga ttatcctaag aatcccaaca
    10021 ggataccggc tgctacggca gaaccgatta cacctgctac gttcggaccc atggcgtgca
    10081 tcaacaggta gttggtcgga tcatattcca gacctacgtt ctgagagata cgggcagagt
    10141 cgggcacggc agacacaccg gagttaccga taagcggatt gatcttattg ccttctttca
    10201 agaacaggtt gaagaacttc acgaacagga tacctgcaca agttgcgatc acgaatgaca
    10261 acgctcccaa accgaagatc ttgatggagt tcaatgtcag gaactgggtt gcttgagtag
    10321 aagcacctac cgtaatacct aacaggatcg tgatcgtatc gatcagcgga ccacgggctg
    10381 tttcagccaa acgacgtgtt acaccacttt ctttcaacaa atttccgaag aacagcatac
    10441 ccaacagagg cagaccggaa ggaacaagga agcaagtcag caacaggcct acgatcggga
    10501 atacgatctt ttccgtggaa gaaacggctc tcggcggttt catgcggatc agacgttctt
    10561 tctgagtcgt cagcaggcgc atgaacggag gctggataat aggaaccagc gccatataag
    10621 agtatgccga tactgcaata gcacccatca agttcggagc taacttggaa gaaaggaaga
    10681 ttgctgtcgg gccgtcggca ccaccgatga taccgattgc accggcctgg ttcggttcaa
    10741 atcccatttg aagagcgatg atatatgctc cgaaaatacc gaactgagcc gctgcaccga
    10801 tcaacatcag tttaggattg gagatcaatg cggagaaatc ggtcatggcc ccgataccga
    10861 ggaagatcaa cggcggatac catccggagg ttacaccctg gtagaggatg ttcagcacag
    10921 aaccttgttc gtaaataccc acctgcaatc ctgcatcttt gaacggaatg ttaccgatca
    10981 ggataccgaa tccgataggg ataaggagca taggctcgaa ttcatattta atagccagga
    11041 agatgaacaa cagaccgaca aggatcatga taaggtgacc cggtgtcgcg ttgtagactc
    11101 ctgtataagt gaggaacaac tccaagtttt ctcccaagaa ctggagaaag ctttcatgag
    11161 ccgtacctgc tgcctgtaat aatactgatc ctaacataat attatcctat tacgacgagg
    11221 tcagcacctt ccagtacgga atcccctttg tttactttta tttcaatgat tttgccgtca
    11281 cggtcggcgt tgatgttgtt ttccatcttc atggcttcga ggacaagtag attctggcct
    11341 ctcttgacag tatcaccgac tttacagtta acctgtagga ttacacctgg cagcggagat
    11401 ttgacagcgc ccttggtggt tgaggctgcc ggacgggaaa taaccggttc gccacttgcc
    11461 gttgtaggag cttgagccgg gcgtttcagt gtaaccatct gtttttttgc cggtttctcc
    11521 atttttacct gatagggagt accgtttact tctacttcag cgatgtcatc cactaccgag
    11581 ctgatatgta ctttatatac gttaccgtta atagtatatt taaaactttt cattcttgtt
    11641 tgtttttaga gataattact ttttgggaac ttcacgcaga ccgtaaatct tggaactcca
    11701 cggagaataa gatctttgaa ccttgcggat cgtcagaacc gtatgttcga tgtcgtggtt
    11761 gtcgtcgctc atttcgtata gagccgcacc gatagccgca aagatttccc cggattcctg
    11821 acctgcattg tctgcaataa cagccgctcc ggccgctttc tgtgcattgc gtttgctggc
    11881 cgcgatcgag agctttccga tttgtttaaa gatgatgaac aacaggaata atccggagaa
    11941 cacaactgcc atggcagtca gggtcatacc gataccccaa gaatcatttt ctttaaagtt
    12001 ctcgattttc tcgttagaat ccaatgttac gttattggtg ctgggtgtaa cttttgtcag
    12061 agctgtccat tcaccttgtc cgtctaaagt tctaccatag ctgacatctg ctttttgtga
    12121 agcagggata acgatctcat cgatcagagt tttaccgtct gcatcgtata acgcaatgta
    12181 attttctttt gatgggtcga gcgtgaaatt gacatggaat gttccccgat ccggttctcc
    12241 gtctgcccag aacaaagtgt gctggcgagg aggaattact gttagaacgt cgcccttcgg
    12301 aatcggatac tttttcgggt tgctcttgtc attagtcaag tagcaaccgg cgatattgac
    12361 cgaaccggcc gaattgttga ataattcgat ccaggcatgg cgtttgccgt aatcatcaac
    12421 aaagttatct tcgttgatga ccagcacttc atttattcgc atggaggttg cacgctgtgc
    12481 ttttgccccg aatgaaacga gcagcgcgaa cagcagcaat acccctattt tcttattaat
    12541 catattcatt tcctgtttta agaattatag aggcagattg tcatgtttct tggcaggatt
    12601 gcttaacttc ttggtctgca attgttgtaa agcacgaata atacggaaac gagtgttacg
    12661 aggttcgata acatcgtcga tatagccata ttgagctgca ttgtatgggt ttgcaaatgc
    12721 ttttttgtat tcggcttctt tttctgcagc gcaagctttc ggatcttccg aggcagccac
    12781 ttcttttgca aagatcactt ctacagcacc gcttgggccc ataactgcga tttcggctgt
    12841 cggccatgcg tagttcatat cgccacgcag atgtttggag ctcatcacac aataggctcc
    12901 accgtaagat ttacgcaatg ttacagttac tttaggcact gtggcttcgc cgtaagcgta
    12961 aagcaatttg gctccgtgca ggataacacc gttgtattcc tggcctgtac ccggtaagaa
    13021 tcccggtacg tcaaccaatg taaccaaagg aatgttgaaa gcatcacaga aacggacgaa
    13081 acggcctgcc ttgcgggagg cgttgctgtc cagacagcct gccattactt tcggctggtt
    13141 ggctacgata ccgacagtct ggccgttaaa acgggcgaaa ccgacgataa tgttcttggc
    13201 atagtcggca tgtacttcca gaaattcgcc gttatcgatg atggttccga taacttcata
    13261 catatcgtaa gcctggttag gattgtcagg gatgatgtcg ttcaggttgt catccagacg
    13321 gtcgatcggg tctttacatt cgatcagagg agtttcttcc aggttgttct gcggcaggaa
    13381 gctgatcaat ttgcggatca actgtaaacc gtcttcttcc gtatcgactg cgaagtgggc
    13441 cacaccggat ttggtcgtat gtacgcttgc gccacctaat tgttcctgtg taacgtcttc
    13501 gcctgtaact gtttttacaa ctttcggacc agtcaggaac atgtaacttg ttccgcgggt
    13561 catgatattg aagtctgtca gggcaggaga gtaaaccgca ccgccggcac atggaccgaa
    13621 gataccggaa atctgaggaa taaccccgga agccaagata ttacgttgga agatttctgc
    13681 ataaccggcc aaggcgttga caccttcctg gatacgtgcg ccacccgagt cgttcagacc
    13741 gataacggga gcacccatct tcatggcctg atccattact ttacagatct tcatggccaa
    13801 tgcttcggat aaagcaccgc cgaacacggt gaaatcctga gcataaatat ataccagacg
    13861 tccgtcgatc gttccgtaac ctgttacgat accgtcgccc aaatacttag ttttttcaat
    13921 accgaagttt gtacaacgat gttgtacgaa catatcgaat tcttcaaaac ttccctcatc
    13981 cagcaacatg gcaatacgtt cgcgtgcggt gtatttacct tttttgtgct gagattcgat
    14041 tcttttttct ccaccaccta aacgagctgt ttcgcgaagg gcgataagct cctttacttt
    14101 ttcaagttgg ttactcattg tactatagat ttgttgttag aaatgaactt atttaattgg
    14161 caattgacga ttgagaattg ccaattgaat agcatcaaat aattgtcaat tctcaattgt
    14221 ccattgtttc ttattttccc ggcatgcaaa gttcggtcag aacgctgcat gtcgatttcg
    14281 ggtgaaggaa tgcaatgttc aagccttctg cacctccacg aggagctttg tcgatcagct
    14341 tgacaccttt tgattcggct tcgtccaatg ctgcctgtac gtcgggaaca gcaaatgcaa
    14401 tgtggtggat accttcacct ttcttttcga taaatttagc gattgtactg tcttcacttg
    14461 tcggctccag caactcgatc ttagtctggc ctactttaaa gaatgcagtt tttactttct
    14521 ggtctgctac ttcttcgatg ttgtagcatt ttagtcctaa aacttcttca taatacggca
    14581 ggcaagcttc gatgctcttt actgcgatac ccaaatgttc gatatgtgta agttccatgt
    14641 caataataat ttagtaattt aatattgctt tttgttctat gttggcaaag gtacactctt
    14701 tttattaata gagaaataat tcgttaatat ttatcagcat gatccggata tgtttaaaaa
    14761 gcatattttt gaaatcatgt ggttaaaaat caacgataag tcgaatattc aattgtcttc
    14821 cggtcaggta attagggatt gcgtactggt ggttgtctat attggtaatc caataatagg
    14881 aactcgtgtt ctttatgtcg aacaagttga aaatatccaa cccgagccaa atgttcttga
    14941 gattgcggaa gaatccgcga tccatgattg catccgttcc cccggcaagc tggtaggaga
    15001 aaccgaggtc tacgcgtttg taggtcggag tacggaaata gccgtcctcg tagcctgtac
    15061 gtggggctgt gacgggaagg ccgccggaca gtacgccttt cagattcagt ttgacacgtt
    15121 tgtatccggg gaaataatcc tgaaaaaaga gcgagacatt ataaccttgg ctgttaggca
    15181 tcggtacata ttcgctccct cggatgcttt gctccgcttt cattagggag aagctgatcc
    15241 aggagtccgt acccggaaca aattcgccga agaatttgac atcgagcccc atcgcatggc
    15301 cttgcgcaca gttctcgccg tagtatcgga ttttgacatt atccaccgta taggggttca
    15361 ggttatccaa ttttttataa tacatatcgg cactgacttt gaaatttctg ccggatgccc
    15421 ggaatgtata atcgcctcct gcaatgacat ggatggaacg ctgtgatttc aggtttttgt
    15481 tcagttgtat gatactgttg ccgtgttcgt cctgcacagt tgtacgtaat tccttataga
    15541 acggagactg ataatacaga ccggaagcca gccgaaatgt caggttctgg tcgaagttcg
    15601 gaatgaaacc tattgaagca cgcgggctga atataaattc cctgttataa ctccaatagc
    15661 tgccgcgtac accaccaacc agcgtgaaca gtccttgttt ggtacgaaac ttgaatacat
    15721 cctgcaaata accggaaata cgtgtgcttt ccagtttgtt atccgagaac aggtttgcga
    15781 tcacgttgac attcccgccc ccttgcggta acgagtatcc ggcggagtcg cgtttttccc
    15841 attcgctgat cttgtcgttg attttctcca actggacggt agcaccccat ttcaacgtat
    15901 tgttttttat gcgagcgaca ccataatgcc cgacattcat gatattggag tgcagacggt
    15961 tgcgagcgtg ctcgttatag cgtgcgatgg ataatttctg tatttctccg cctccttctt
    16021 cggctgcatc tcccagccag taatcaccgg caatatcata tccttcctct tccttactgg
    16081 taaaggcgga tgcttgcaag ccgagttccg tattgtcgtt caggttatgc tttaaagtga
    16141 gtgctccgaa taacgtttcg aacttatccc gttcctggcc actcatgaat actttaaatt
    16201 ttttggcatt tgttgccgtt ccaaaagaag tctctcgggt gtggggaatg aacttataat
    16261 tgtttatggc taagttcccg agaaagttga tctcccattt gggagcaagc tggtatgtca
    16321 tataagtctg caaatcaatg aaattaggat catattcggc atccgtatcg gttgttttca
    16381 aaagagatcg tcctgttttg taacggaaac cggtcacctg tgtgaacttg ccggaagaac
    16441 tgcccacata agcattggct cccagcaggc tggcggaagc cgaaccttcg aatcctttcg
    16501 gttttttgta ggtgatgtcc agcacggaac tcatcttgtc cccataacgg gcttcgaatc
    16561 ctccggcgga gaaattgacg gcttccgtca tgtccgggtt gataaaactc aacccttcct
    16621 gttgtccgga acggatgagc agcggacgga acacttccag tccgttcaca tatacgatgt
    16681 tttcgtcata gctgccgccg cgtacggagt attgcgaact taattcgtta ttggaagtaa
    16741 cgcctgcaaa tgtaacgacc agactttcaa tgcttcctcc ggcagggtcg gggagtagtt
    16801 tgacgcggtc ggcattcagg gtttcaaggg tggttgtctg ctttcggatg gcggtagcta
    16861 cgacttctcc cagttcgagt gatgtatagt tcatctgcac gttgagacgc atatctttgg
    16921 ttacctgagg taggatcctt tcggccttgt tgtagcccag gcatgaatag ataagcgtca
    16981 ccgagtcacc ggtagcgacc gaaagcgagt agtggccttt ttcattactc atcgtcccgt
    17041 ttaacgtgtt cttgacccgg atattgacca agtccagcgg attaccgtcc gcgtcgcgga
    17101 tataaccgct gattttggca cgtccctgcc cgaaagcact tatcgaaaat aatataaata
    17161 gtagtgtagc tattgcacga atcttcatat tccatctaat tattaaatct acaaacgcgg
    17221 gaaacaacga tttattttca atgaaaggca atttctcact atctttgtgc cttatataaa
    17281 taattaagga aagaagatgc ctttaaacct acagaagaac ttgccagctg ttgagctgtt
    17341 gaagaaagag cacatctttg tgatggactc gttgcgtgcg tctgagcagg acattcgtcc
    17401 gctacgtgta gttgtgctga acttgatgcc actgaagatc acgacggaga cggaccttgt
    17461 tcgcctcctg agcaataccc ccttgcaagt ggagctcgac tttatgaaga taaaaggcca
    17521 tactcccaag aacacgccga tcgagcatat gaaggaattc tataaagact ttgacgagat
    17581 gcaggatgat ttttacgacg gcatgattat cacaggtgct ccggtagagc agatgccttt
    17641 cgaggaagtg aattattggg aggaagtgac cgagatattc gattgggcgc gtacgcatgt
    17701 gacttctacc ttatatatat gctgggcggc gcaagccggg ttgtaccatt tttatggtgt
    17761 ccccaaatat gatctgccag ccaagatgtt cggcgtgttc cgccatacgt tgcgcgagcc
    17821 ctatgtgccg atcttccgag gcttcgacga cgagttctat gtgccgcaca gccggcatac
    17881 ggagatacgc cgcgaggatg tgatgaaagt tcccgatttg acgctcttgt ccgaaagcga
    17941 agagtctggt gtctatatgg cgatggcgcg cggaggacgc gagtttttta tcaccgggca
    18001 ttccgaatac tcgccttaca cgctgaatga cgagtatatg cgcgacgtga acaagggatt
    18061 gcctattgcc gttccccgta actattaccg taataacaat ccggccctcg gtccggtggt
    18121 ccgctggcgt ggtcatgcca atcttctgtt caccaactgg ctgaactatt atgtctatca
    18181 ggaaaccccg tttcgtatcg aggatatcag caagttgggt aatttgtaat caagaaataa
    18241 gaaataatag catgcaaaca aaatcccgtc ctatagaact tctctctccg gctaaagacc
    18301 tcaattgcgg gattgaagcg attaatcacg gtgccgatgc cgtctatatc ggtgcgccca
    18361 agttcggtgc gcgttccgct gccggcaact ctttggaaga tatacgcgag ctttgcgagt
    18421 atgcccacct gtatggagcc cgtatctacg ttacgctcaa cacgatcctg aaagaagatg
    18481 agttggaaga agccgaacgg atgatctggg atctctggcg tgtcgggacg gatgccctga
    18541 tcattcagga tatggggatt acccggctga acctgcctcc tattccgctt cacgccagca
    18601 cgcagacgga caatcgtaca ccggaaaagg tccgtttcct cgaagccgca ggctttacac
    18661 aggtggttct ggcacgtgaa ttgtcgctga acgagattcg ccggatatcg gaagcgacta
    18721 ccgttccgct ggaagtattc gtgcacggcg ccctctgtgt cagctatagc gggcaatgtt
    18781 atctgagcgc cgctttgagt ggacgtagtg ctaaccgcgg agaatgcgcc caatattgcc
    18841 gcctgcccta tacgatggtt gatgcgacag ggacggagat cgtcacccat aaacacttgc
    18901 tttcgctcaa ggacatgaac cgctccgacc agctggaagc cctgttggat gcaggtgttt
    18961 cttccctcaa gatcgaaggg cggttgaaag atgccggcta tgtcaagaat atcacggctt
    19021 attatcggaa gaagttagat gcagtcctgt cccgccgtcc ggaatatcgt cgtgcttctg
    19081 ctggtcgaag cacttatacg ttcgagccgg tagctgaaaa gagttttaac cgtgggttca
    19141 ccccgttcct tttggaggga cggacggcgg atattaccgc ttttaataca cctaagtcgt
    19201 tgggcgaacc tgtcgggacg gtcaaagaga tcaaaggcaa ttcttttact gtggccggct
    19261 tgaagcagtt gaacaacgga gacgggcttg ttttcttcaa taggaaaggc gaattggaag
    19321 gttttcgtgt aaaccgggtg gaggcaaacc gggtgtttcc gctggatatg ccgcagcttg
    19381 cccccaagac tcctctttac cgcaatttcg accaggcgtt tgataaactg ctagccaagc
    19441 cttcagccga acgcaagctg tccctggaga tcgagttctt ggacaatccc ttcggtttta
    19501 cgctttgtat ggaggatgag acgggagcac ggatcatgct gaccgagccg tttgcaaaag
    19561 agctggcgcg tcgtgaacag caggataata tccggacaca gctatccaag ttggggaata
    19621 cgcctttcga ggcatcggaa gttgtggtcg gtttgtctga aaactggttc gttccctctt
    19681 ctctgcttgc cgatatgcgc cgtagaggag tggagaagtt gctggaagca cgccgtgccc
    19741 gctatcctcg tgagacagtg aaacgtgtgc agccgtccgt gtcgatacct ttccccgaac
    19801 gccaacttac ttatttgggg aatgttgcca acgggaaagc ccgttcgttc taccaggatc
    19861 acggggtgga acagatcgac ccggcatttg aactgtctcc ccggaaagat gttccgttga
    19921 tgtttaccaa acactgcctg cgctacagca tggggtggtg tcctacttat caaaaagaca
    19981 agtctcccta caaggaaccg tattatctgc tttataaaga tacgcgcctc cggttgcagt
    20041 tcgactgcaa gcattgtcag atgttggtat ttgaaagttg aaaattatga gaacgctatt
    20101 gtcaggacgg ataagaatga ctgtccggtg aaagaagcca tgatccgttt gacaaaagta
    20161 ttccagcaat aaaggagccg ataggtatgt gataacagtt tcatagggat ggaacgacag
    20221 tttcatgggg atgaaaaaga agtttcatcc ctatgaaaat aaagtttccc ttgcatgaaa
    20281 ataaagtttt ctttaagggg aacgggaagg tagtgcaagg ttatatagcc tttcctaata
    20341 actccatata ttttgccacc cctttcgtgt cttctggagc cggactccag ggagcgaaat
    20401 tttccggagc gagcggagcg aacggccctt ccttgatttc atatatgaca gagccggatt
    20461 ctagaactaa cagcccgtgc catgttcccg cctttatttc ggcgccgtag acaccttctt
    20521 tcggatcgag tatctgtgtt tgggtgattt cccctttgtt gtcaaagagg aatacagcaa
    20581 tgcgaccgcg cagcaggagg aatatttcat cttttttagg gttcagatgg cggtgtgggc
    20641 ggaggtaggt tcccggttcc agggcattga gcaaacggtt gacgggatcg tccaaatgct
    20701 catgaaaatt gtagttcatg cgtagccgag gcgactgttt ggcacgcccg gtcgtttcat
    20761 ccaataaagc ttcgtttatg atcttcatgc gaataattga ttactggagg acgaatgtac
    20821 aaaataaata ttggctggta tgccatttct ccgtacattt gcagaaacct gtaaataaaa
    20881 cagaatgaaa cctgctctaa cttattacgc tctgctggtc ttacttctgg catcctgctt
    20941 ttcctgcaaa acagattcgg agaagaaaaa gtttgttatc ggcgtctcgc agtgtacgct
    21001 tgaaggttct tggcgtaaat cgatgttgct ggatatgaag gtgcaggcct ccgaatatcc
    21061 gggcgtctcc ctgttagtcg aggatgcagc ggacagtagt ttgttgcagg tggagcagat
    21121 acgtagcctg ataaaacgta aggtcgatct attgattatc tccgccaatg aatcggaacc
    21181 tgtcactcct attgcgattg aggcctaccg tgccggcatt ccgactatcc tggtagaccg
    21241 gaagatcagt tcggacgaat atacgactta tatcggtggt aacaattacg agatcggtcg
    21301 ccaggccggc tttttcgtga accgacaggt gaaagagaaa tatcctaccg tattggaagt
    21361 atggggcttg tccggttctt ctccggcgca ggatcgccat cgcggtttta tggaggtttt
    21421 gaactcccgc atcaaggtga aggaaatatt cgggaaatgg aagccggaaa cggtggagaa
    21481 ggagatagcg gaaatggatt cgctggagga ggtggatgtt gtgtttgccc ataatgatgt
    21541 gatggcaatg gctgcccgca gggcaatcga aaggatgcat cccggattgg cggacaggat
    21601 tagctttgtg gggatcgatg ccgtttcggg acggggatcg gggctggaag ccgtcatgca
    21661 cggagagttg gccgcttcgg tcttgtatcc gacgggtggg agccttgcta tccgtgtagc
    21721 catgcagata ttgaacggag aagatgtgtc ccggcaatat ttgctatctt ctgccttgat
    21781 cgataagaac aatgccggaa cgctgtttat ccagtccgaa caggtggtcg actatcagca
    21841 ccagatcgag ttgcaacggg agaatttgga gagtatgctt tccaaataca cgttcctcca
    21901 aaactccgtc ggcattatcc ttttgctgat ggggatgttg cttttgtccg ccttgtacgt
    21961 ggtccatgtg aaccgggcgg tgaagcggaa gaaccgcgag ctgaaacgta cgaacttgca
    22021 ggtgcaacag caaaaagaag aattggctga ggcaaaccgt tatattgaga agtcgacggc
    22081 tcagaaactg caattcttta ccaatatcac acacgagatc aagacgccgt tgacgttgat
    22141 cctcggtccg ctcggcaagc tgtcgaaaga ggctccggaa ggttcttcat tggcagacga
    22201 tatccgtatc attcggaaaa atgcggaaag gttgaagaga gtcgtggacc agttacttga
    22261 ttttcgaaag gtagagagca ataagatgaa tatgcgggtc ggagaggtag atttagttgc
    22321 ttttgtggca gaagtgaaat cttatttcga tacgatggct gccaccaaac agatacattt
    22381 cacgtttgag catgactgcc cttctgttaa tatatgggta gacagagata agatggagaa
    22441 gattctggcc aatcttttgt ccaatgcatt caagttcacg ctggacggag gtacggtcac
    22501 gatccgcctg aaggataaag gagatcaggt cgagctttct gtcgaagata atggcaaagg
    22561 cattccgtcg gaaaatattg cttccgtctt tgaccgtttc tttaccggtg accagaacta
    22621 tgtgacgggg acggggatcg gtctgcactt gacgcgtgag ttcgtccaca tgcacaaagg
    22681 cacgatccgg gtggagagtg ttccgcataa gagtactgtc tttacggtca tcctcttgaa
    22741 aggtaaatct cattttgacg aatcttgtat attcgatctt tccgtaaccg agctttccag
    22801 tggtgtcgcc gacttgaaca cggatgaatt gcaggaggtt ttgaaccgta cctacaatta
    22861 tactgttctg gtcgtagaag atgatcttga tatacagagt tacttgcagg cggaattaaa
    22921 acagaacttc cgtgtgttgg ttgccgataa cggcgtgaag gctttggagg tactgatgaa
    22981 cgaagagatc tcgatggtta tcagcgatgt gatgatgccg gaaatgaacg gtttcgatct
    23041 ttgtcgtaag atcaagtcgg atattgtcct gagtcatctt ccggttatgc tgttgactgc
    23101 tttgtccgac gacaagcaac agatgtacgg ggctgccagt ggtgcggacg cgtatatcca
    23161 gaaacctttt aacatagaag tcgtgaaact gcgtatcatc aagctgctgg aggatcgtgt
    23221 ccggttgcgt gaggcttatg ctcgcgatgc ttcttcgcct gctgtttccg tgaaggagga
    23281 aaaagcggga agcatggacg atctttttat gaatcgtttc ttgaaactga tcgaagagtc
    23341 ctatgccgat ccggatttca gtattgagaa aggtagtgaa aaattgggct tgtcgcgtgt
    23401 gcatctttac cggaaggtga aggagcttgc cggagtgaca ccgaccgatt tcctgcgtaa
    23461 ctatcgtttg aagaaagctg ctgctctact ccgacggaaa gccgggaatg tgaatgaggt
    23521 ggcttatgcg acgggtttcg gttcgcctgc ttatttctcg aaatgtttta aagccgttta
    23581 caatattact ccgacggagt atctggaaaa ggaataatat tcttctcttt gataacgctc
    23641 gttacatttg tgtaacattt gtgcatgtaa ctcgaaaata agagtataat gtaacaagtg
    23701 ttatcaatct tgtagcatta gttatcgtcg catctgctac ctgtctctat ctttgcatcg
    23761 tagataataa attatccttg tcaaataaac tataatgaaa caatgcaaag caacaataag
    23821 aaaccggtcg tagtaggcat aggagaactc ctgtgggaca tgttgccaac aggaaagaaa
    23881 gcaggtggtg ctcctatcaa ttttgtctac catgcgtcgc ggttgggggc ggaaggatat
    23941 gctatcagcg ccgtgggaga cgatgggctg gggcgcgaaa tcctcgaaga actggataat
    24001 aattcgatcc ggtatctgat cgagaaagtc ccttatccga ccggaacggt acaggttact
    24061 ctgcaggatg gtatccctga ctatattatt aatgaacgtg tagcttggga tcatctttct
    24121 ccgacgtcaa atgcgattga tttggccgaa cgggcgggtg ccatttgctt cggtacgtta
    24181 ggacagcgtt ccgcacagtc gagagagacg atacaagcga ttctttcttt tgccccggac
    24241 gatgcttatc gttgttttga catcaatttg cgtcagcatt attatacgaa agagttgatc
    24301 gaagagtcgc tttatctagc aaatatgttg aaggtgaatg acggggagtt ggtcgtcctg
    24361 cgggatatgt ttcatttgga aggaacggac aaggaggtgg ctcattggtt tatagaacac
    24421 tataatctcc gcttggtggt tctgacggcc ggaggagctt atagtacgat atataccgct
    24481 aatgaagaat cgactttgca aaccccggaa gtgcaggtgg cggatacggt tggagcaggt
    24541 gatgctttct ccggagcact ggtcatttcg ttgctgaaag gggcttcgct aagggaagcg
    24601 catgaatttg ccgtccgcac agctgcttat gtctgtac
//
