Select genomic region:
Overview
2.1
38.1
68.1
115.1
119.1

### Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaGPGAIPCF_2 (original name was: gnl|Prokka|GPGAIPCF_2)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 2.1 | NRPS,cyclic-lactone-autoinducer | 24,119 | 70,691 | HTTPCA/prepiscibactin/piscibactin | NRP+Polyketide | 4%

gnlProkkaGPGAIPCF_45 (original name was: gnl|Prokka|GPGAIPCF_45)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 38.1 | lanthipeptide-class-ii | 64 | 23,030 | xantholipin | Polyketide | 6%

gnlProkkaGPGAIPCF_75 (original name was: gnl|Prokka|GPGAIPCF_75)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 68.1 | ranthipeptide | 14,685 | 26,245 |

gnlProkkaGPGAIPCF_122 (original name was: gnl|Prokka|GPGAIPCF_122)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 115.1 | RRE-containing | 1 | 10,463 |

gnlProkkaGPGAIPCF_126 (original name was: gnl|Prokka|GPGAIPCF_126)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 119.1 | cyclic-lactone-autoinducer | 1 | 8,836 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 2.1 | NRPS,cyclic-lactone-autoinducer | 24,119 | 70,691 | HTTPCA/prepiscibactin/piscibactin | NRP+Polyketide | 4%
Region 38.1 | lanthipeptide-class-ii | 64 | 23,030 | xantholipin | Polyketide | 6%
Region 68.1 | ranthipeptide | 14,685 | 26,245 |
Region 115.1 | RRE-containing | 1 | 10,463 |
Region 119.1 | cyclic-lactone-autoinducer | 1 | 8,836 |

No secondary metabolite regions were found in these records:
  gnlProkkaGPGAIPCF_1 (original name was: gnl|Prokka|GPGAIPCF_1)
  gnlProkkaGPGAIPCF_3 (original name was: gnl|Prokka|GPGAIPCF_3)
  gnlProkkaGPGAIPCF_4 (original name was: gnl|Prokka|GPGAIPCF_4)
  gnlProkkaGPGAIPCF_5 (original name was: gnl|Prokka|GPGAIPCF_5)
  gnlProkkaGPGAIPCF_6 (original name was: gnl|Prokka|GPGAIPCF_6)
  gnlProkkaGPGAIPCF_7 (original name was: gnl|Prokka|GPGAIPCF_7)
  gnlProkkaGPGAIPCF_8 (original name was: gnl|Prokka|GPGAIPCF_8)
  gnlProkkaGPGAIPCF_9 (original name was: gnl|Prokka|GPGAIPCF_9)
  gnlProkkaGPGAIPCF_10 (original name was: gnl|Prokka|GPGAIPCF_10)
  gnlProkkaGPGAIPCF_11 (original name was: gnl|Prokka|GPGAIPCF_11)
  gnlProkkaGPGAIPCF_12 (original name was: gnl|Prokka|GPGAIPCF_12)
  gnlProkkaGPGAIPCF_13 (original name was: gnl|Prokka|GPGAIPCF_13)
  gnlProkkaGPGAIPCF_14 (original name was: gnl|Prokka|GPGAIPCF_14)
  gnlProkkaGPGAIPCF_15 (original name was: gnl|Prokka|GPGAIPCF_15)
  gnlProkkaGPGAIPCF_16 (original name was: gnl|Prokka|GPGAIPCF_16)
  gnlProkkaGPGAIPCF_17 (original name was: gnl|Prokka|GPGAIPCF_17)
  gnlProkkaGPGAIPCF_18 (original name was: gnl|Prokka|GPGAIPCF_18)
  gnlProkkaGPGAIPCF_19 (original name was: gnl|Prokka|GPGAIPCF_19)
  gnlProkkaGPGAIPCF_20 (original name was: gnl|Prokka|GPGAIPCF_20)
  gnlProkkaGPGAIPCF_21 (original name was: gnl|Prokka|GPGAIPCF_21)
  gnlProkkaGPGAIPCF_22 (original name was: gnl|Prokka|GPGAIPCF_22)
  gnlProkkaGPGAIPCF_23 (original name was: gnl|Prokka|GPGAIPCF_23)
  gnlProkkaGPGAIPCF_24 (original name was: gnl|Prokka|GPGAIPCF_24)
  gnlProkkaGPGAIPCF_25 (original name was: gnl|Prokka|GPGAIPCF_25)
  gnlProkkaGPGAIPCF_26 (original name was: gnl|Prokka|GPGAIPCF_26)
  gnlProkkaGPGAIPCF_27 (original name was: gnl|Prokka|GPGAIPCF_27)
  gnlProkkaGPGAIPCF_28 (original name was: gnl|Prokka|GPGAIPCF_28)
  gnlProkkaGPGAIPCF_29 (original name was: gnl|Prokka|GPGAIPCF_29)
  gnlProkkaGPGAIPCF_30 (original name was: gnl|Prokka|GPGAIPCF_30)
  gnlProkkaGPGAIPCF_31 (original name was: gnl|Prokka|GPGAIPCF_31)
  gnlProkkaGPGAIPCF_35 (original name was: gnl|Prokka|GPGAIPCF_35)
  gnlProkkaGPGAIPCF_40 (original name was: gnl|Prokka|GPGAIPCF_40)
  gnlProkkaGPGAIPCF_41 (original name was: gnl|Prokka|GPGAIPCF_41)
  gnlProkkaGPGAIPCF_42 (original name was: gnl|Prokka|GPGAIPCF_42)
  gnlProkkaGPGAIPCF_43 (original name was: gnl|Prokka|GPGAIPCF_43)
  gnlProkkaGPGAIPCF_44 (original name was: gnl|Prokka|GPGAIPCF_44)
  gnlProkkaGPGAIPCF_46 (original name was: gnl|Prokka|GPGAIPCF_46)
  gnlProkkaGPGAIPCF_47 (original name was: gnl|Prokka|GPGAIPCF_47)
  gnlProkkaGPGAIPCF_48 (original name was: gnl|Prokka|GPGAIPCF_48)
  gnlProkkaGPGAIPCF_49 (original name was: gnl|Prokka|GPGAIPCF_49)
  gnlProkkaGPGAIPCF_50 (original name was: gnl|Prokka|GPGAIPCF_50)
  gnlProkkaGPGAIPCF_51 (original name was: gnl|Prokka|GPGAIPCF_51)
  gnlProkkaGPGAIPCF_52 (original name was: gnl|Prokka|GPGAIPCF_52)
  gnlProkkaGPGAIPCF_53 (original name was: gnl|Prokka|GPGAIPCF_53)
  gnlProkkaGPGAIPCF_54 (original name was: gnl|Prokka|GPGAIPCF_54)
  gnlProkkaGPGAIPCF_55 (original name was: gnl|Prokka|GPGAIPCF_55)
  gnlProkkaGPGAIPCF_56 (original name was: gnl|Prokka|GPGAIPCF_56)
  gnlProkkaGPGAIPCF_57 (original name was: gnl|Prokka|GPGAIPCF_57)
  gnlProkkaGPGAIPCF_58 (original name was: gnl|Prokka|GPGAIPCF_58)
  gnlProkkaGPGAIPCF_59 (original name was: gnl|Prokka|GPGAIPCF_59)
  gnlProkkaGPGAIPCF_60 (original name was: gnl|Prokka|GPGAIPCF_60)
  gnlProkkaGPGAIPCF_61 (original name was: gnl|Prokka|GPGAIPCF_61)
  gnlProkkaGPGAIPCF_62 (original name was: gnl|Prokka|GPGAIPCF_62)
  gnlProkkaGPGAIPCF_63 (original name was: gnl|Prokka|GPGAIPCF_63)
  gnlProkkaGPGAIPCF_64 (original name was: gnl|Prokka|GPGAIPCF_64)
  gnlProkkaGPGAIPCF_65 (original name was: gnl|Prokka|GPGAIPCF_65)
  gnlProkkaGPGAIPCF_66 (original name was: gnl|Prokka|GPGAIPCF_66)
  gnlProkkaGPGAIPCF_67 (original name was: gnl|Prokka|GPGAIPCF_67)
  gnlProkkaGPGAIPCF_68 (original name was: gnl|Prokka|GPGAIPCF_68)
  gnlProkkaGPGAIPCF_69 (original name was: gnl|Prokka|GPGAIPCF_69)
  gnlProkkaGPGAIPCF_70 (original name was: gnl|Prokka|GPGAIPCF_70)
  gnlProkkaGPGAIPCF_71 (original name was: gnl|Prokka|GPGAIPCF_71)
  gnlProkkaGPGAIPCF_72 (original name was: gnl|Prokka|GPGAIPCF_72)
  gnlProkkaGPGAIPCF_73 (original name was: gnl|Prokka|GPGAIPCF_73)
  gnlProkkaGPGAIPCF_74 (original name was: gnl|Prokka|GPGAIPCF_74)
  gnlProkkaGPGAIPCF_76 (original name was: gnl|Prokka|GPGAIPCF_76)
  gnlProkkaGPGAIPCF_77 (original name was: gnl|Prokka|GPGAIPCF_77)
  gnlProkkaGPGAIPCF_78 (original name was: gnl|Prokka|GPGAIPCF_78)
  gnlProkkaGPGAIPCF_79 (original name was: gnl|Prokka|GPGAIPCF_79)
  gnlProkkaGPGAIPCF_80 (original name was: gnl|Prokka|GPGAIPCF_80)
  gnlProkkaGPGAIPCF_81 (original name was: gnl|Prokka|GPGAIPCF_81)
  gnlProkkaGPGAIPCF_82 (original name was: gnl|Prokka|GPGAIPCF_82)
  gnlProkkaGPGAIPCF_83 (original name was: gnl|Prokka|GPGAIPCF_83)
  gnlProkkaGPGAIPCF_84 (original name was: gnl|Prokka|GPGAIPCF_84)
  gnlProkkaGPGAIPCF_85 (original name was: gnl|Prokka|GPGAIPCF_85)
  gnlProkkaGPGAIPCF_86 (original name was: gnl|Prokka|GPGAIPCF_86)
  gnlProkkaGPGAIPCF_87 (original name was: gnl|Prokka|GPGAIPCF_87)
  gnlProkkaGPGAIPCF_88 (original name was: gnl|Prokka|GPGAIPCF_88)
  gnlProkkaGPGAIPCF_89 (original name was: gnl|Prokka|GPGAIPCF_89)
  gnlProkkaGPGAIPCF_90 (original name was: gnl|Prokka|GPGAIPCF_90)
  gnlProkkaGPGAIPCF_91 (original name was: gnl|Prokka|GPGAIPCF_91)
  gnlProkkaGPGAIPCF_92 (original name was: gnl|Prokka|GPGAIPCF_92)
  gnlProkkaGPGAIPCF_93 (original name was: gnl|Prokka|GPGAIPCF_93)
  gnlProkkaGPGAIPCF_94 (original name was: gnl|Prokka|GPGAIPCF_94)
  gnlProkkaGPGAIPCF_95 (original name was: gnl|Prokka|GPGAIPCF_95)
  gnlProkkaGPGAIPCF_96 (original name was: gnl|Prokka|GPGAIPCF_96)
  gnlProkkaGPGAIPCF_97 (original name was: gnl|Prokka|GPGAIPCF_97)
  gnlProkkaGPGAIPCF_98 (original name was: gnl|Prokka|GPGAIPCF_98)
  gnlProkkaGPGAIPCF_99 (original name was: gnl|Prokka|GPGAIPCF_99)
  gnlProkkaGPGAIPCF_100 (original name was: gnl|Prokka|GPGAIPCF_100)
  gnlProkkaGPGAIPCF_101 (original name was: gnl|Prokka|GPGAIPCF_101)
  gnlProkkaGPGAIPCF_102 (original name was: gnl|Prokka|GPGAIPCF_102)
  gnlProkkaGPGAIPCF_103 (original name was: gnl|Prokka|GPGAIPCF_103)
  gnlProkkaGPGAIPCF_104 (original name was: gnl|Prokka|GPGAIPCF_104)
  gnlProkkaGPGAIPCF_105 (original name was: gnl|Prokka|GPGAIPCF_105)
  gnlProkkaGPGAIPCF_106 (original name was: gnl|Prokka|GPGAIPCF_106)
  gnlProkkaGPGAIPCF_107 (original name was: gnl|Prokka|GPGAIPCF_107)
  gnlProkkaGPGAIPCF_108 (original name was: gnl|Prokka|GPGAIPCF_108)
  gnlProkkaGPGAIPCF_109 (original name was: gnl|Prokka|GPGAIPCF_109)
  gnlProkkaGPGAIPCF_110 (original name was: gnl|Prokka|GPGAIPCF_110)
  gnlProkkaGPGAIPCF_111 (original name was: gnl|Prokka|GPGAIPCF_111)
  gnlProkkaGPGAIPCF_112 (original name was: gnl|Prokka|GPGAIPCF_112)
  gnlProkkaGPGAIPCF_113 (original name was: gnl|Prokka|GPGAIPCF_113)
  gnlProkkaGPGAIPCF_114 (original name was: gnl|Prokka|GPGAIPCF_114)
  gnlProkkaGPGAIPCF_115 (original name was: gnl|Prokka|GPGAIPCF_115)
  gnlProkkaGPGAIPCF_116 (original name was: gnl|Prokka|GPGAIPCF_116)
  gnlProkkaGPGAIPCF_117 (original name was: gnl|Prokka|GPGAIPCF_117)
  gnlProkkaGPGAIPCF_118 (original name was: gnl|Prokka|GPGAIPCF_118)
  gnlProkkaGPGAIPCF_119 (original name was: gnl|Prokka|GPGAIPCF_119)
  gnlProkkaGPGAIPCF_120 (original name was: gnl|Prokka|GPGAIPCF_120)
  gnlProkkaGPGAIPCF_121 (original name was: gnl|Prokka|GPGAIPCF_121)
  gnlProkkaGPGAIPCF_123 (original name was: gnl|Prokka|GPGAIPCF_123)
  gnlProkkaGPGAIPCF_124 (original name was: gnl|Prokka|GPGAIPCF_124)
  gnlProkkaGPGAIPCF_125 (original name was: gnl|Prokka|GPGAIPCF_125)
  gnlProkkaGPGAIPCF_127 (original name was: gnl|Prokka|GPGAIPCF_127)
  gnlProkkaGPGAIPCF_128 (original name was: gnl|Prokka|GPGAIPCF_128)
  gnlProkkaGPGAIPCF_129 (original name was: gnl|Prokka|GPGAIPCF_129)
  gnlProkkaGPGAIPCF_130 (original name was: gnl|Prokka|GPGAIPCF_130)
  gnlProkkaGPGAIPCF_131 (original name was: gnl|Prokka|GPGAIPCF_131)
  gnlProkkaGPGAIPCF_132 (original name was: gnl|Prokka|GPGAIPCF_132)
  gnlProkkaGPGAIPCF_133 (original name was: gnl|Prokka|GPGAIPCF_133)

Compact view
gnlProkkaGPGAIPCF_2 - Region 1 - NRPS,cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 24,119 - 70,691 nt. (total: 46,573 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
KnownClusterBlast
NRPS/PKS modules
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate cluster in NRPS and PKS regions.
Genes are shown in predicted order, and are only present when containing at least one complete module.
A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
NRPS/PKS products
NRPS/PKS substrates
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 24118 - 70691:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (Cys)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS substrate predictions
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg2_53: Cys
  Search NORINE for peptide: strict or relaxed
  AMP-binding (553..948): Cys
  nrpys: Cys
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      Polar, uncharged (aliphatic with -SH) (Cys)
    Small clusters prediction:
      Polar, uncharged (aliphatic with -SH) (Cys)
    Single AA prediction:
      Polar, uncharged (aliphatic with -SH) (Cys)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DLYNMSMIWK
    Nearest Stachelhaus code(s):
      Cys DLYNMSMIWK (94% 8Å match)
    Stachelhaus code match:
      100% (strong)
ctg2_54: diOH-Bz
  Search NORINE for peptide: strict or relaxed
  AMP-binding (25..431): diOH-Bz
  nrpys: diOH-Bz
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
    Large clusters prediction:
      Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
    Small clusters prediction:
      Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
    Single AA prediction:
      dhb (diOH-Bz)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      PLPAQGVLSK
    Nearest Stachelhaus code(s):
      diOH-Bz PLPAQGVLCK (79% 8Å match)
      Sal PLPAQGVLNK (74% 8Å match)
    Stachelhaus code match:
      90% (moderate)

gnlProkkaGPGAIPCF_45 - Region 1 - lanthipeptide-class-ii
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 64 - 23,030 nt. (total: 22,967 nt) Show pHMM detection rules used
Region on contig edge.
lanthipeptide-class-ii: cds(LANC_like and DUF4135)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Lanthipeptides
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.

#### Lanthipeptide(s) for ctg38_13

ctg38_10
Leader:
MKTCSERNEQRINSLQLSESLEDEIKELDGKNVEAGDVIFT
Core:
TDTSSFLTIVCC
Core with dehydrations:
DhbDDhbDhaDhaFLDhbIVCysCys

#### antiSMASH-DB 4.0 matches for ctg38_10

100.0% NZ_CP102267.1 and 2 others:
NZ_JADMOE010000006.1 Lanthipeptides: I2G55_RS05425_lanthipeptide NZ_LT635469.1 Lanthipeptides: BQ7352_RS14540_lanthipeptide
Lanthipeptides: NQ550_RS10225_lanthipeptide
1
TDTSSFLTIVCC
12
TDTSSFLTIVCC
1
TDTSSFLTIVCC
12
50.0% NZ_CP113781.1: Lanthipeptides: GGADHKLB_RS14125_lanthipeptide
2
DTSSFLTIVCC
12
+ + FLTI+CC
2
NCTHFLTILCC
12
40.0% NZ_AP025566.1: Lanthipeptides: MWL92_RS00840_lanthipeptide
4
SSFLTIVCC
12
+SF TI+CC
7
TSFCTIICC
15
with 10 more sequence matches
33.3% NZ_CP036524.1: Lanthipeptides: LAJLEIBI_RS18025_lanthipeptide
4
SSFLTIVCC
12
++F TI+CC
7
TTFFTIICC
15
31.6% NZ_CP036170.1: Lanthipeptides: HDCHBGLK_RS18795_lanthipeptide
4
SSFLTIVCC
12
+FLTI CC
11
GTFLTIYCC
19
29.2% NZ_CP048626.1: Lanthipeptides: GXM18_RS04600_lanthipeptide
2
DTSSFLTIVCC
12
D +SF TI CC
14
DNASFFTIFCC
24
26.9% NZ_CP070036.1 and 3 others:
NZ_JADMPO010000043.1 Lanthipeptides: I2I27_RS16805_lanthipeptide NZ_JADNGF010000061.1 Lanthipeptides: I2E06_RS15650_lanthipeptide NZ_JAQMLK010000037.1 Lanthipeptides: PNW18_RS16660_lanthipeptide
Lanthipeptides: I6K72_RS03970_lanthipeptide
4
SSFLTIVCC
12
S+FLTI CC
18
SAFLTIYCC
26
20.6% NZ_JADPCB010000035.1: Lanthipeptides: I4W51_RS14990_lanthipeptide
3
TSSFLTIVCC
12
T +FLTI+CC
25
TGAFLTILCC
34
17.9% NZ_CP094681.1: Lanthipeptides: K5I26_RS05295_lanthipeptide
1
TDTSSFLTIVCC
12
+D + FLTI CC
28
SDCALFLTIFCC
39
17.9% NZ_JAOQJV010000004.1: Lanthipeptides: OCV65_RS05205_lanthipeptide
4
SSFLTIVCC
12
S FLTI+CC
31
SGFLTIICC
39
17.6% NZ_MCGI01000004.1 and 1 other:
NZ_MPDJ01000004.1 Lanthipeptides: BLA28_RS33805_lanthipeptide
Lanthipeptides: BEH84_RS33640_lanthipeptide
1
TDTSSFLTIVCC
12
T+++ FL+I CC
23
TESTPFLSIFCC
34
15.8% NZ_LT969517.1 and 1 other:
NZ_QVLV01000012.1 Lanthipeptides: DXC51_RS29565_lanthipeptide
Lanthipeptides: C1733_RS32195_lanthipeptide
1
TDTSSFLTIVCC
12
T ++ FL+I CC
27
TASTGFLSIFCC
38
15.4% NZ_JADNBM010000025.1 and 2 others:
NZ_JAQDZW010000013.1 Lanthipeptides: PGT55_RS13345_lanthipeptide NZ_QVMC01000003.1 Lanthipeptides: DWV46_RS15805_lanthipeptide
Lanthipeptides: I2A62_RS14145_lanthipeptide
4
SSFLTIVCC
12
++FLTI CC
31
TAFLTIFCC
39

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Lanthipeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

ctg38_10 - Class II
  Cleavage pHMM score: -4.00
  RODEO score: 0
  Monoisotopic mass: 1198.6 Da
  Molecular weight: 1199.4 Da
  Number of bridges: 2
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    1217.4 Da N = 1
    1235.4 Da N = 2
    1253.4 Da N = 3

gnlProkkaGPGAIPCF_75 - Region 1 - ranthipeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 14,685 - 26,245 nt. (total: 11,561 nt) Show pHMM detection rules used
Region on contig edge.
ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or (YcaO or TIGR03604))))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

gnlProkkaGPGAIPCF_122 - Region 1 - RRE-containing
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1 - 10,463 nt. (total: 10,463 nt) Show pHMM detection rules used
Region on contig edge.
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

gnlProkkaGPGAIPCF_126 - Region 1 - cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1 - 8,836 nt. (total: 8,836 nt) Show pHMM detection rules used
Region on contig edge.
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.