LOCUS       gnlProkkaGPGAIPCF_45   22967 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GPGAIPCF_45.
ACCESSION   gnlProkkaGPGAIPCF_45
VERSION     gnlProkkaGPGAIPCF_45
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 02:01:06
            Original ID  :: gnl|Prokka|GPGAIPCF_45
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 63
            Orig. end    :: 23030
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22967
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:12967]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12967
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..22967
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22967
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             45..374
                     /locus_tag="ctg38_1"
                     /transl_table=11
                     /translation="MKYVFPEYKENVVLGNGKLQLNPMSYQVIYEGKEIDLTPREFEVL
                     YLLALKPNWVMPKTTIYHSVWGIHYHDDQIPYRTVEYVIWKIRKKMGYDIIETLVNVGY
                     RLKKL"
     CDS             503..1000
                     /locus_tag="ctg38_2"
                     /transl_table=11
                     /translation="MNKNKKSAKQYHQSIITALEKKVNDMKDSAYSGLYSEIAFIIGIA
                     VIMIDTFFPSEKTEANCVLKIILIAISVFCMFYFARKVKTVNEVEEEKKFWPNFFIQWA
                     TGLGYINMPVAVIAILVTFDKVKAWTLFMMGVAVILTGLTLIDALVKTSKILKKENVGK
                     RK"
     CDS             complement(1502..2155)
                     /NRPS_PKS="Domain: ACPS (104-162). E-value: 6.4e-08. Score:
                     24.3. Matches aSDomain: nrpspksdomains_ctg38_3_ACPS.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012:4'-phosphopantetheinyl transferase (Score: 110.9;
                     E-value: 8.9e-34)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_3"
                     /transl_table=11
                     /translation="MLVLYLSTISLEWKNIDSDLMQFVSKERRKKINQYFHVLDKKLSL
                     YSALITRIGLSVISGLNHTELCFYYSSNHKPLLLSNPKYDFSISHSNGSIISCISANSP
                     VGADVEKISYPPFDIMNLIFNQQEIQYINNASDMERIFRFYKMWTQKESYYKMLGIGLT
                     GAMIQCNSLTPDLSKLFYTWQEDNYMYCICGKNVSERTLIKLSETEVQNYFIPI"
     aSDomain        complement(1670..1843)
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg38_3_ACPS.1"
                     /evalue="6.40E-08"
                     /label="ctg38_3_ACPS.1"
                     /locus_tag="ctg38_3"
                     /protein_end="162"
                     /protein_start="104"
                     /score="24.3"
                     /tool="antismash"
                     /translation="VGADVEKISYPPFDIMNLIFNQQEIQYINNASDMERIFRFYKMWT
                     QKESYYKMLGIGL"
     CDS             2411..2827
                     /locus_tag="ctg38_4"
                     /transl_table=11
                     /translation="MKIEDIVQLLENVYKYNISELSIKSENEKVIIKNDTDDKVVDTVR
                     VVTEKTEGESKNKSDEENIIKSPLVGRFYAAPSVGSDNYVKVGDKVEEGQTLAIIEAMK
                     LMNEIKSEYSGTVKSILVENEELVEYGQPLFVLV"
     CDS             2839..4179
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090:acetyl-CoA carboxylase biotin carboxylase (Score:
                     606; E-value: 1.7e-183)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_5"
                     /sec_met_domain="ATP-grasp (E-value: 6.6e-09, bitscore:
                     27.6, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 2.8e-12,
                     bitscore: 38.6, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFEKILIANRGEIAVRIIKACKEMGIKSVAIYSEADKDALHTKMA
                     DEAICIGPAPSGDSYLNMENIISAAVGTGSQAIHPGFGFLSENSLFAEKCKVCNITFIG
                     PTSEVICKMGNKVEARNMMRNAGVPIISGSWTPVFGVCEAKKVALELGFPIMIKAAAGG
                     GGKGMRISNTEDDFNENFVTAQMEANSSFRDGTMYLERYIEAPNHIEFQILADKYGNVI
                     QLGERDCSIQRHHQKIIEEAPSPKISAKLRKEMGNIAIKVAKTVNYEGAGTVEFLLDKF
                     GKYYFIEMNTRIQVEHGVTEMISNVDIVKEQIKIAAGYSLEFKQEDILLQGHAIECRLN
                     AENPKKGFVPCPGKINNVYFPSGNGVRIDTALFNGCSVSPFYDSMLAKIIVYDSERKTA
                     IRKMKSVLKKIKIDGIITNLEFQNAILNHCDFEEGNFTTDFIVDKFS"
     CDS             4203..5858
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059:acetyl-CoA carboxylase, carboxyl transferase,
                     (Score: 442.1; E-value: 5.1e-134)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_6"
                     /transl_table=11
                     /translation="MNEKDNRTDRNKENIPAVPPGMWIKCTKCGKLIYRKELEKNKFIC
                     MKCGKYFRMPSENRILDIIDEGSFVELFTDVLDKNPIDFPGYSEKKEIIKKETNLEEAV
                     ITGKASIGHIEVMLGVCDTRYLMGSMGYIVGEKITKLFENATKAQLPVIMINCSGGARM
                     QEGIISLMQMAKTVDSVKQHSDAGLLYISVLTDPTTGGVAASFAMLGDVILAEPNSLIG
                     FAGPRVIEQTTKQKLPVGFQTSEFLYEHGFLDMIVIRRELKERIYEILKAHQKPKVIER
                     KRKTISACTFCDYKDSWKKVQLSRKIDRPTTVDYITHVFERFIEFHGDGETGEDQAIIG
                     GIAFLDNIPVTVIGHQKGKTTEERIIRNFGMAHPEGYRKAIRLMKEAEKFRRPIITFID
                     TPGAACGVEAEKRGEASAIAKCIYEMFNLKVPILSILIGEGGSGGALGLAVANEVWAME
                     NSTYSILSPEGFASILWKNEKRAKEAANLMKMTAKDLLDLGVIEKILPEGNEASEFKVI
                     TDFLQVQILDFIYNMSLKNEDEIVASRETRFRSF"
     CDS             complement(5906..6253)
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 62.4; E-value: 1.1e-18)"
                     /gene_kind="other"
                     /locus_tag="ctg38_7"
                     /transl_table=11
                     /translation="MKDNNFVNLGKRIREKRLSRNLTQEALAEKADVGTTHISHIETGC
                     TKLSLTTFISIANALDVSADELLCDCINQASNVYETEISLLLKNCSTKEICFIHDLVKN
                     TLISLHNRNLK"
     CDS             6380..7228
                     /locus_tag="ctg38_8"
                     /transl_table=11
                     /translation="MEYILFNRIALIRYVNYLVESLKSCSQKEKKAEVINMPRIAIVDD
                     QEEYLEEICNLIEKFYFKNGIPYVVNTFSNAQLLLYEMEEKLYFDIYLLDIEMPGINGL
                     SLAEKIRSMDDAGYIVFITSHLKFLINGYDYFAYQFIPKNNLKKKLISTLESLQKRLDI
                     EEEKFYQICTNHRYEKILYKDIYYVYKDEKYAIFVTQNGNIPIRETLKNIYKDLEQKEF
                     IFIDRGYIVNVVHIMSLYKNTIYLRNSKNLKISRTYTEEVKKRIHTYWKEHTTNGRDIH
                     T"
     CDS             7206..8507
                     /locus_tag="ctg38_9"
                     /transl_table=11
                     /translation="MEEIYILNVLQYLLGYFEIYMCFEILRKVYKKENTKIKQCFEILI
                     CISLAVIEAINRSFRLYSILLIAVVIIVISITFSLIYKIKLRYTLLHTSLYCLSLELLD
                     LFIIFTMGIVLHKEDLGIVIGRQNSISRILALFLGRALMFLISLAIVRYKELIDKNRIG
                     SLVLILLSEIIGVIYFQSVYAGDSIPDLAKGYYMYFVIIILAIMFFAIYSIYRSALEES
                     KIIKLRNRMLERNYEDLKVYYNDSRTLFHDYRAHITLLQKYLEENQIDKACLYLNSINK
                     PLAELEKKIYTGNAVIDLVMNYKLSELKEKNIKIEYDIMPIDFGNYHFEESDIFVILYN
                     LFDNAIEACENIYTREKWIYLSLRLINNMFMLCIQNSYEIEPKYENGELLTIKTDKHFH
                     GIGMKSVKKIVEKYEGQLEYDNKQNIFEVSITLF"
     CDS             8592..8753
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_10"
                     /transl_table=11
                     /translation="MKTCSERNEQRINSLQLSESLEDEIKELDGKNVEAGDVIFTTDTS
                     SFLTIVCC"
     CDS_motif       8592..8714
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MKTCSERNEQRINSLQLSESLEDEIKELDGKNVEAGDVIFT"
                     /locus_tag="ctg38_10_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       8715..8753
                     /prepeptide="core"
                     /locus_tag="ctg38_10_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.00"
                     /molecular_weight="1199.4"
                     /monoisotopic_mass="1198.6"
                     /core_sequence="TDTSSFLTIVCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKTCSERNEQRINSLQLSESLEDEIKELDGKNVEAGDVIFT
                     "
                     /leader_location="[8591:8714](+)"
                     /alternative_weights="1217.4"
                     /alternative_weights="1235.4"
                     /alternative_weights="1253.4"
     CDS             8785..9111
                     /locus_tag="ctg38_11"
                     /transl_table=11
                     /translation="MENEFTGFNCFMEESSEVGKAYIDMILQQEKASALDNKTRELAYI
                     AVLAATGIMGGLLYHVQSAKKLGASRDEVKSAILVGLPAVGLTIIDPLEAALKVFDGKS
                     DQIL"
     CDS             complement(9342..9866)
                     /locus_tag="ctg38_12"
                     /transl_table=11
                     /translation="MATIDLIVLGMLKTSALSAYDIQKLVEYRNISKWVKISTPSIYKK
                     VLQLEEKGLIKGTTIKEGKMPEKAIYTLTDTGEKEFEKLMLDISSKPIHIFLDFNAVIV
                     NINNLSPDKQKKCLSDIKNNIEILKAYLEDNINSKEQKPEIPTAGMAVLQQQLILVQAI
                     ENWIATLPNVF"
     CDS             10001..12967
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     613.7; E-value: 9.9e-186)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_13"
                     /sec_met_domain="DUF4135 (E-value: 3.8e-81, bitscore:
                     265.1, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 6.4e-45, bitscore:
                     145.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRERYLFERKYIRKDNELKIPSKWEKLIGEDTVKILCKEYKEISS
                     FFSENTQYYEQEAPSNVEYMEILEMYLAGSYKSEIIIENTMKDKLFFTFYIPFFKLARY
                     YSRRKYGDILEKYFSKGIYEELYSALACVATRVLVNEIQFLENKLVGKNANEKYSAYVE
                     MYLSNDEYIEELFQFYPLLLRCILEKICSVVEFYHQLISRWEKNVIEIKKCINIDNTEI
                     TKIKKVGDNHRNGKHTVKIFLKNGNAVFYKPRNLRISKIYYECLNILYEYVGLSCFKYR
                     IADFGEYGWEEEIKYQKCKNKDEVKNYYVRMGCHIALSYILDIQDFHYENLISHGEYPV
                     FIDIEVLCGHIKKNYIPLTANEKAKLFVENSVLGSGILPRGNKEMDIFCALSGKGGIKT
                     GRKRLILINSKTSDMKFVYKDAKTKKGYNSPQINHKEYRYNGFVDEICLGFRKSYEYIW
                     KNNKIFEGRFQNFSSRMLYNHTQNYSKLIQLSYHPMFMTDGGERQLILSKNFFFHIRIN
                     PKNGKDLFESELYAMLKGDIPYFSFLSNKKELYMDNHQMIKEYFTITPEQYIRMRIKSL
                     SSQDLYIQQYLLNNAIKGSTVHLENRMDYMHDTNFSVIKICKQIADYLMKIGIKNSLKT
                     DINWIISLTGTIHISDMFLYEGIAGMIVFFAALNQVAPTRAYLEVQNILLNKLLEYTMN
                     NSSSKAYSGAFCGEASIIYTYLVLYKISNEEKYIKYAKIHENKLFASLEIDRMGDLLYG
                     NAGAVIIYLNMYELTMDKKYILRAEIAANYILKNLKEKYSIFNNIEGNKISRLDRGIAH
                     GGSGYSICFTRLFGKTKKRKYLNIALELLKYDIKRNKKENQRSRKIYWCHGAAGIVLAQ
                     QEILKYIEDGSYQHIFEDYQTKISMIENNFNIELDSLCLCHGILGNIMIIEQLTGKIPC
                     VPWTSTLSKLNYFIKKNLWTNLENGNPGFMMGLAGIGYAVLYLDENTKKFPNILKLEL"
     CDS             13070..14467
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 334.6; E-value: 1.3e-101)"
                     /gene_kind="transport"
                     /locus_tag="ctg38_14"
                     /transl_table=11
                     /translation="MKGHNKKMELLGSAPIPKALLAMGIPTMIGMMISAIYNLVDAYFV
                     GSLGTSQMGAISVTYPLSQVIVGLGLLFGNGAGSYISRLLGRGNNDDAKKVASTALYSG
                     LLLGIIFIIGTLAFLEPILKFLGTTESIMPYAIKYARIFIAASIFNIFNVMMNNIITSE
                     GAAKISMFAMLSGALLNMILDPIFINVLNMGVTGAAIASAIGQALSTVVFLSYILMKKS
                     IFTFKIKDCCYSKENMKEILKIGVPTLVFQLLTSLSIILINNQANALSVTHTKEYVDSV
                     IAGMGAVTRIVSMGSLMVFGFIKGFQPIAGYSYGAKNFKRLNESIKTSILWSTVFCALF
                     GLILILFPATIISKFTAGDMELVRIGQASLRANGFSIMLFGFYTVYSSLFLALGKGLEG
                     FILGACRQGICFVPIILLLPSLVGISGILYAQPIADLISAIITVFMAINLHKSLEKERL
                     SYIKNVE"
     CDS             14910..16268
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062:glycosyltransferase, MGT family (Score: 205.4;
                     E-value: 2.9e-62)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_15"
                     /sec_met_domain="MGT (E-value: 1e-36, bitscore: 119.1,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFYRHNKFFHEKDNILQIRTFLPIYKKIVIFFSGHIVLFKENYSE
                     KYMGRGKKMSKVLFLNIPSHGHINPTLGLVEGLVKQGDEVLYFTTEEFRKKVESMGATF
                     ISYGSKSDFFVPKNKKPGKSILDDLLNRIDEVLNRADIIEYILKQIQGMKFDYIIYGSM
                     FPYGNVISQILNIPAISSFAVFAKPKVFMEKGNEEFIKNHKATDTYQKLYMKLETLYGV
                     QMPPMLDLFFNKGELNIAYTSELFVSNIKEEYDDSFLFIGPPVYDRKEKIEFPFKKING
                     RKVIYISLGTVFNSIDTKLYETFFKAFSDYDGIVVMSAFKMDISKFHIPENFIVQNYVP
                     QSEMLKYVEGAITHGGMNSTSDLIYNNVPFVTIPIGADQRYIASRVSELGATICLNKDN
                     ISPQLLSDSMKRVITERKYKEAVEKISISFKDAGGYKKALMEIRKFKILHSIE"
     CDS             16288..17241
                     /locus_tag="ctg38_16"
                     /transl_table=11
                     /translation="MQKYSEDLTLAHEYYREQDYKNCLKVYDILFHKGEQLSIGNLKEY
                     AISLQKNMRYFESIEIARKILDKKRVDIDIFLNMCICLGKIGKYSDALEYYNKILKINK
                     NYNIQIGYYAYLLGQVGKNEMADFYYKIAIDIEPDNAWYISHYAFFLQRIKEYSRSEYY
                     YKVALNKDKNNSWVSKRYAYFLKELKGKEKAYSYYEQLFVENPYNYNYYINAAELAFIS
                     NDMEKSLRYLEKANSINKPKVMEIILRFYWAIYYILSDDLKDFEKEALALKSLRRQYTE
                     FIHRDLTDLSFYISNNLSEIKKQKYEYISSILYKGE"
     CDS             17246..18067
                     /locus_tag="ctg38_17"
                     /transl_table=11
                     /translation="MKIIDLSFNVEPNLSEPMSIKIKTRPHSGGSKFGRKIIFMGKRSL
                     KDKAMAVIHYMSGKERITKKSFPDQEFINEQRISLSVHTGTHLDAPSHFGTRCEGKKPK
                     TIDEIPLEWCYGNGVVLNFCNKGPCEEISVEDVKKELERIEYYIQENDIVLIRTDTDKK
                     WGKPNYFYEAPGMSREATKFLVESGVKIIGIDCYSLDRPFMAMVKQYYRTNDKKCLWPA
                     HFYGREKEYCHIERLTNLDKIPMNYGFKFCCFPIKLKEMGAAWVRAVAIIE"
     CDS             18119..18355
                     /NRPS_PKS="Domain: PP-binding (2-66). E-value: 2.7e-13.
                     Score: 42.2. Matches aSDomain:
                     nrpspksdomains_ctg38_18_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_18"
                     /sec_met_domain="PP-binding (E-value: 3.1e-13, bitscore:
                     42.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQKIYEILKERFGIEDTINSDTDLVNQLGFESISLVELASVLSK
                     ETGVKVTHSQAIKWTTVKSILSTLAANSKDNNA"
     aSDomain        18125..18316
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg38_18_PP-binding.1"
                     /evalue="2.70E-13"
                     /label="ctg38_18_PP-binding.1"
                     /locus_tag="ctg38_18"
                     /protein_end="66"
                     /protein_start="2"
                     /score="42.2"
                     /tool="antismash"
                     /translation="QKIYEILKERFGIEDTINSDTDLVNQLGFESISLVELASVLSKET
                     GVKVTHSQAIKWTTVKSIL"
     CDS             18367..18843
                     /NRPS_PKS="Domain: Polyketide_cyc2 (5-148). E-value:
                     2.5e-08. Score: 26.3. Matches aSDomain:
                     nrpspksdomains_ctg38_19_Polyketide_cyc2.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128:cyclase/dehydrase (Score: 73.7; E-value:
                     2.7e-22)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_19"
                     /transl_table=11
                     /translation="MGYTVNSIIIKKEMNELFEIINDVRNWPELHNYQDVKILEKEELL
                     DGRRKIVFQVTGNKEEEPVEIWTSQRIIDVTNMCARGVRLEPMYPFRHWILDVVLSVEK
                     EGTKMTWIQDFSMDKNSGFTEEAVEEMINKGSKKELQIFKEKIESGIVSSKTEL"
     aSDomain        18382..18810
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg38_19_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="2.50E-08"
                     /label="ctg38_19_Polyketide_cyc2.1"
                     /locus_tag="ctg38_19"
                     /protein_end="148"
                     /protein_start="5"
                     /score="26.3"
                     /tool="antismash"
                     /translation="NSIIIKKEMNELFEIINDVRNWPELHNYQDVKILEKEELLDGRRK
                     IVFQVTGNKEEEPVEIWTSQRIIDVTNMCARGVRLEPMYPFRHWILDVVLSVEKEGTKM
                     TWIQDFSMDKNSGFTEEAVEEMINKGSKKELQIFKEKIE"
     CDS             18959..20215
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (4-416). E-value:
                     2.7e-53. Score: 173.2. Matches aSDomain:
                     nrpspksdomains_ctg38_20_PKS_KS.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) t2ks"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 404.7; E-value:
                     7.9e-123)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_20"
                     /sec_met_domain="t2ks (E-value: 1.6e-147, bitscore: 483.9,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRVVVTGIGLITPIGIGKEEFWKNNKEGKSGICDMPELEKFGFE
                     SKAYGYVKNFKPEQLGLTLREIRRMDRITQFGVLCTDQAVKDSKIDLSKIDKNRVGVNI
                     ANAVAGTKFMDEEFSVLTNNGKEVVNPEDISPYAYARSMPNTTSNEVSYRYGFNGTCCT
                     MATGCTTGIDSIGFAYDQIRCGELDVMICGAAEAPITPITIAAFEAIGTLSTNNNPPEK
                     ASRPFDDTRNGFVLAEAAGILVLEELGHALNRGAHIYGEIAGYGSVNNAMHMTGLKPDG
                     EDLSRAIKIAIEEANVTPFEIDYINAHGSGTKQNDINETGAYKKVFGELAYKIPMSSTK
                     SMTGHPLGAASAVEAIVCCLALENNFMPPTINYNKKDALCDLDYIPNCGREKNLNVVLT
                     NASGFGGLHAAMILKKYID"
     aSDomain        18971..20206
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg38_20_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.70E-53"
                     /label="ctg38_20_PKS_KS.1"
                     /locus_tag="ctg38_20"
                     /protein_end="416"
                     /protein_start="4"
                     /score="173.2"
                     /tool="antismash"
                     /translation="VVTGIGLITPIGIGKEEFWKNNKEGKSGICDMPELEKFGFESKAY
                     GYVKNFKPEQLGLTLREIRRMDRITQFGVLCTDQAVKDSKIDLSKIDKNRVGVNIANAV
                     AGTKFMDEEFSVLTNNGKEVVNPEDISPYAYARSMPNTTSNEVSYRYGFNGTCCTMATG
                     CTTGIDSIGFAYDQIRCGELDVMICGAAEAPITPITIAAFEAIGTLSTNNNPPEKASRP
                     FDDTRNGFVLAEAAGILVLEELGHALNRGAHIYGEIAGYGSVNNAMHMTGLKPDGEDLS
                     RAIKIAIEEANVTPFEIDYINAHGSGTKQNDINETGAYKKVFGELAYKIPMSSTKSMTG
                     HPLGAASAVEAIVCCLALENNFMPPTINYNKKDALCDLDYIPNCGREKNLNVVLTNASG
                     FGGLHAAMILKKY"
     CDS             20254..21492
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (5-403). E-value:
                     4.4e-45. Score: 146.2. Matches aSDomain:
                     nrpspksdomains_ctg38_21_PKS_KS.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) t2fas"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 359.2; E-value:
                     3.9e-109)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_21"
                     /sec_met_domain="t2fas (E-value: 5.5e-101, bitscore: 330.3,
                     seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRRRVVITGLGVISPSGNDVETFWESLKQGKSSIGPITKFDTSD
                     FDVKIAGEVKNFDIKKYGFPFMLTRQLDEFTHYAMAATKMALDDSMINLEMVDRTRMGV
                     FAGNCLGGVGFGEKELYNLYREGWQCVSPYQSISWFYTAPQGQISIFYKLKGYSKTFVA
                     DRISSDVALGYAYQSIMLNRLDTCLVCGTEAGVFPYGMSLFSSSDVLSKKRDACYCPYD
                     LKRNGMILGEGAGTLVIEELEHALKRNAPIYGEILSFSNNCDGVHHKEKNKNGKKYKEV
                     IESCIRKANISYDEIDYINLDGAALWEDDVIETNVLKEIWGKEIGTVFLSCPKSMFGNT
                     FGAAGALDAIINCLAIKNNTVPPTINYEDQDSNCDLNYTPNKALHRNINTVLQIARGRG
                     GINSAMLLREFKE"
     aSDomain        20269..21462
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg38_21_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="4.40E-45"
                     /label="ctg38_21_PKS_KS.1"
                     /locus_tag="ctg38_21"
                     /protein_end="403"
                     /protein_start="5"
                     /score="146.2"
                     /tool="antismash"
                     /translation="VVITGLGVISPSGNDVETFWESLKQGKSSIGPITKFDTSDFDVKI
                     AGEVKNFDIKKYGFPFMLTRQLDEFTHYAMAATKMALDDSMINLEMVDRTRMGVFAGNC
                     LGGVGFGEKELYNLYREGWQCVSPYQSISWFYTAPQGQISIFYKLKGYSKTFVADRISS
                     DVALGYAYQSIMLNRLDTCLVCGTEAGVFPYGMSLFSSSDVLSKKRDACYCPYDLKRNG
                     MILGEGAGTLVIEELEHALKRNAPIYGEILSFSNNCDGVHHKEKNKNGKKYKEVIESCI
                     RKANISYDEIDYINLDGAALWEDDVIETNVLKEIWGKEIGTVFLSCPKSMFGNTFGAAG
                     ALDAIINCLAIKNNTVPPTINYEDQDSNCDLNYTPNKALHRNINTVLQIARGRGGINS"
     CDS             21532..21975
                     /locus_tag="ctg38_22"
                     /transl_table=11
                     /translation="MPVIKKEIILKGTTKEIFKRMSEYSFIQEMNSSANVCTKIIFKKP
                     RIIRYGIEVKNVGYWESERVFIPEKNVIITQRKEPMGPFKYLVVIYVLEKDNQGTKFTY
                     IEEFDVCDNYQNEVEKIYSDISKKVNPILQKITDYFNSEHILQ"
ORIGIN
        1 ggaatgagaa aagttgaatt tacaaatcaa gaggagacat acacatgaag tatgtttttc
       61 cagaatataa agagaatgta gtgttgggca acgggaaatt acagttaaat ccaatgtcct
      121 atcaggttat ctacgaagga aaggagatag acctgacacc cagggaattt gaagttttat
      181 atctactggc tttaaagcca aactgggtaa tgccaaagac aactatttat cattctgtat
      241 ggggtattca ttatcatgat gatcagatac catacagaac agtagaatat gtgatatgga
      301 agataagaaa aaagatggga tatgatatta ttgaaacgtt ggtcaatgtg gggtatagac
      361 tgaagaagtt ataagtatat atatatcatg catacaatnn nnnnnnnntg gtcaatgtgg
      421 ggtatagact gaagaagtta taattttctg gagatataat tgatatgaaa cggtatgtta
      481 ttacgaatgg aggacatatt acatgaataa aaataagaaa agtgcgaaac agtatcacca
      541 atctataatt actgctttag agaaaaaagt aaatgatatg aaagactccg cttattcagg
      601 attgtatagc gaaatagcgt ttatcattgg aatagcagtt atcatgatag atactttttt
      661 tccgtcggag aaaacggaag ctaattgtgt cttgaaaata atactgatag ctatatctgt
      721 attctgtatg ttctatttcg ccagaaaagt gaaaacagtg aatgaagtgg aagaagagaa
      781 aaagttttgg ccgaactttt ttattcaatg ggcaacaggg ttagggtata taaacatgcc
      841 tgtagctgtg atcgctattt tggtaacatt tgataaggtc aaagcatgga cattatttat
      901 gatgggagtt gctgtaattt tgaccggttt gactttaata gacgcccttg taaaaacttc
      961 taaaatttta aaaaaagaaa atgttggtaa gcggaaataa gattgactaa aaaaaatgag
     1021 gtaaaaggtg tattggatat gattcacacc ttttaccttt taaattgcgt aattattttt
     1081 ttagtgataa acattacatc atgattattc cgaaagaagg cggttttgcg aagcatctac
     1141 aggagattgg cgactgatta aaagcagcaa cagtttccgc agcaggagtg caaggtattc
     1201 ttcattttta tttgaaaacc ggggttgaaa gcccaaggat gtttaaccag gcgttttaac
     1261 agaaatatgg gggaacacct agcaaatatc ggagaatatg ttttgaaaac ggaatatgga
     1321 aaattagata aaactatggg aactataact tatggataga gaaaaataga gcagatatga
     1381 aagggacata tctactttta ctatagggat taattaaagg tatagatttt taaaaagttc
     1441 ataataaagg ttagacagat ttgcaggaaa tagaattttt acatatcctg ttaatctatt
     1501 tttatatggg tataaaataa ttttggactt ctgtttcaga caattttatt aaggtgcgtt
     1561 cagatacatt ttttccacaa atacaataca tataattatc ttcttgccaa gtgtaaaata
     1621 atttggataa atcaggggtt agagaattgc attggatcat agcaccagta agcccgattc
     1681 cgagcatttt ataataggat tctttttgtg tccacatttt gtaaaatcta aaaattcgtt
     1741 ccatatctga ggcattgtta atgtattgaa tttcctgttg attgaaaatg agattcataa
     1801 tatcaaatgg tggataagat attttttcca catcagctcc aactggagaa ttagctgata
     1861 tacaactgat tatagaacca ttcgaatgag aaatgctaaa gtcatattta ggattagata
     1921 ataatagtgg cttatgattt gaagaatagt aaaaacataa ttcggtatga ttcaaaccag
     1981 atataacgct taatccgata cgagtaataa gagcggaata aagagaaagc tttttgtcaa
     2041 gtacatgaaa atattgattt attttttttc ttcgttcttt ggaaacaaat tgcattaaat
     2101 cagaatctat atttttccat tcgagagaaa tagttgataa atataacact agcatgagta
     2161 aatcctccta agtataataa tgagaagttt accataggaa cataaaaatt tcaaatgtaa
     2221 aatgggcatt ttgtaaggag atttttgtgt aataaagaca aaaatatgca agtaaatcca
     2281 aaatcgtcta taagaatata aaatatgcta tgttaaaaaa acagtataaa agatagggta
     2341 agaaaaggga atattctatc taaatctaat aatcttattc ttataatatt atgcgatatg
     2401 gaggcaagga atgaaaatcg aagacattgt acagttatta gaaaatgtat acaaatataa
     2461 tatatcagaa cttagtataa aaagtgaaaa tgagaaggtt atcatcaaaa atgacactga
     2521 tgataaggta gttgatactg tgagagttgt aactgaaaaa acagagggtg aaagtaaaaa
     2581 taaaagtgat gaagaaaata ttataaaatc acccttagtg gggcgttttt atgcggctcc
     2641 ttctgttgga agtgataatt atgttaaggt gggagacaaa gtagaagagg gacaaacact
     2701 tgctatcatc gaagcaatga aattaatgaa tgaaattaag agtgaatata gcggaactgt
     2761 taaaagcata ttagtagaaa atgaagaact ggtggagtat ggacagccct tatttgtttt
     2821 agtttgaaag gagtttttat gtttgaaaaa atactgattg ctaatagagg agaaatagct
     2881 gtacgaatta taaaagcatg taaagagatg ggaattaagt ctgtagctat atattcagag
     2941 gcagataaag acgctttaca tacaaaaatg gcagatgagg cgatatgtat aggacctgca
     3001 ccgtcaggag atagttatct caatatggaa aatattatta gtgcagctgt aggaacagga
     3061 tcccaggcaa ttcacccagg ttttggattt ttatcagaaa atagtctttt tgcggaaaag
     3121 tgcaaagtat gtaatattac attcattggt ccaacatcag aagtgatttg taaaatggga
     3181 aataaagttg aagcacgtaa tatgatgaga aatgcgggag ttccgattat atcaggaagc
     3241 tggactcccg tttttggtgt gtgtgaagca aaaaaagtgg cattagagct tggatttcca
     3301 attatgataa aggctgcagc aggtggtggt ggaaaaggta tgagaatatc caatacagaa
     3361 gatgatttta atgaaaactt tgtaacagcc cagatggaag ctaatagttc gtttagagat
     3421 ggaacaatgt atttagagag gtatatagaa gcaccaaatc atatagaatt tcaaatactt
     3481 gcagataaat atggaaatgt tatacagttg ggagaaagag attgctctat tcaaaggcat
     3541 catcagaaaa ttattgaaga agctcctagc cccaaaatat cggcaaaatt aagaaaagaa
     3601 atgggaaata tagcgattaa agtggcaaaa actgtaaact acgaaggtgc aggtacagta
     3661 gaatttttgc ttgataaatt cggaaaatat tattttattg agatgaatac acgtattcaa
     3721 gtagaacatg gagttacaga gatgatatct aatgttgaca ttgttaagga acagataaaa
     3781 attgctgcgg gatattcgct tgagtttaag caagaagata tcttactgca gggtcatgct
     3841 atcgaatgta gacttaatgc ggaaaatccg aagaaggggt ttgtcccatg tcctgggaaa
     3901 attaataatg tttattttcc aagcggtaat ggtgttcgaa ttgatactgc attatttaat
     3961 ggttgtagtg tttcaccttt ttatgattct atgcttgcaa aaattatagt gtatgattca
     4021 gaacgaaaaa cggctattag aaaaatgaaa agtgttttaa aaaaaataaa aatagacgga
     4081 attataacta atttagaatt tcaaaatgcc attctaaatc attgtgattt tgaagaaggt
     4141 aattttacaa cggactttat tgtagataag tttagttgat aagaaataag aggaatgaaa
     4201 ttatgaacga gaaagataat cgaacagata gaaataaaga aaatatacca gcagtaccac
     4261 ctggaatgtg gattaagtgt acgaaatgtg gaaaattgat ttatagaaaa gagttagaaa
     4321 aaaataaatt tatttgtatg aaatgtggaa aatattttag aatgccttcg gaaaatagaa
     4381 ttttggatat tatagatgaa ggatcatttg ttgaactgtt tacagatgta ttggataaaa
     4441 atccaattga ttttccagga tatagtgaaa aaaaagagat aattaaaaag gaaactaatc
     4501 tagaggaagc tgttattaca ggaaaagcgt caatagggca tatagaggtt atgcttggtg
     4561 tatgtgatac aagatatctg atgggaagta tggggtatat tgtaggcgag aaaataacaa
     4621 aattattcga aaatgcaacc aaagcccagc taccagttat tatgattaat tgttcaggag
     4681 gcgcacgtat gcaagaaggc atcatatcct tgatgcaaat ggcaaagaca gtagattcgg
     4741 taaaacaaca ttcagatgcg gggttattgt atatatcagt tttgacagat ccgacaaccg
     4801 gtggggtggc agctagtttt gctatgttag gtgatgtgat attggctgaa ccaaattcat
     4861 taattgggtt tgcgggtcca cgagtaattg aacaaactac aaaacagaag ttgcctgtag
     4921 gatttcaaac ctcagaattt ttatatgaac atggattcct tgatatgatt gttataagaa
     4981 gagaattaaa ggaacgtatc tatgaaattc ttaaagctca ccaaaagcca aaggttatag
     5041 aaagaaaacg taaaacaatt tctgcgtgta ctttttgtga ttataaggac agttggaaaa
     5101 aagtacaatt atcaagaaaa atagatagac cgacgacagt agactatatc acccatgtat
     5161 ttgaaagatt tatagaattt catggagacg gtgaaaccgg agaggatcaa gcaataattg
     5221 gaggtatagc ctttttagat aatattccag ttacagttat aggacatcaa aagggaaaaa
     5281 cgacagaaga aagaattatt agaaatttcg gaatggcaca ccctgaagga tatagaaaag
     5341 caattcgtct tatgaaagaa gcggagaaat ttagaagacc aattataaca ttcatagata
     5401 cacctggtgc agcatgtgga gttgaggctg aaaaaagagg agaagcatct gcaatagcaa
     5461 aatgtatata tgaaatgttc aatttaaaag taccgatttt gagtatactt ataggcgaag
     5521 gtgggagtgg aggagcttta ggtttagctg ttgcaaatga ggtttgggct atggaaaatt
     5581 ctacatattc aatactttct ccagaaggtt tcgcttctat tttatggaaa aatgaaaaac
     5641 gtgcaaaaga ggcagcaaac cttatgaaaa tgacggcaaa agatttatta gatttaggag
     5701 tgattgagaa aatattacca gaagggaatg aagcatcaga gttcaaagta attacagatt
     5761 ttctacaagt tcaaattctt gattttatat ataatatgtc ccttaaaaat gaagatgaaa
     5821 tagtggcttc aagagaaaca agatttagaa gtttttagat agaattgata aagactgaag
     5881 cgaaaaaaac ttcagtcttt attgattatt ttaagttgcg attatgtaaa gagataagtg
     5941 tattttttac taggtcatgt ataaagcata tttctttagt tgaacagttt tttaaaagta
     6001 gagaaatttc tgtttcatat acatttgatg cttgattaat gcagtcacat aataattcat
     6061 cggcagatac atcaagagca tttgcaatag aaataaaggt tgttaaactt agtttggtac
     6121 agcctgtttc aatatgcgaa atgtgtgttg ttccaacatc tgctttttct gccaaagctt
     6181 cttgggtaag attccgggat aggcgttttt cacgaatacg tttacctagg tttacaaaat
     6241 tgttatcttt cataattgca cctccatgat tatatgtgta ttgtatgtgc aatcaaaata
     6301 tttcttaata acctatatgt gcatatagac taaataatga tagttttaag atgtttagag
     6361 agtgtatgaa ataaagcaca tggaatatat attatttaat cggattgcac taataagata
     6421 tgtaaactat ttggtagaat cgctaaaatc atgttcacag aaagaaaaaa aggcagaggt
     6481 gataaatatg ccaagaatag caattgtaga tgatcaggaa gagtatttag aagaaatttg
     6541 taatttaata gagaagtttt attttaaaaa tggaattcca tacgttgtga atactttttc
     6601 aaatgcacag ttgttactat acgaaatgga agaaaaattg tattttgata tttatctatt
     6661 agatattgaa atgcctggga taaacggact atctttagct gaaaaaatac gttctatgga
     6721 tgatgcagga tatattgtgt ttatcacgtc acatttaaaa tttttaataa atggatatga
     6781 ttattttgca tatcagttta tccctaaaaa taatttgaaa aagaagttga tatcgacatt
     6841 agaatcatta caaaaaaggc tggatattga agaagaaaag ttttatcaaa tatgtactaa
     6901 tcatagatat gagaaaattt tatataagga tatctattat gtgtataaag atgaaaaata
     6961 tgcgattttt gttacccaaa acggaaatat acctatacga gaaaccttga agaacattta
     7021 taaagattta gaacaaaaag aatttatttt tatagataga ggatacattg ttaacgtcgt
     7081 acatattatg agtttatata aaaatactat ttacttgcgt aatagtaaaa atcttaaaat
     7141 tagtagaaca tatactgaag aggtaaaaaa gagaattcac acttattgga aggaacacac
     7201 aacaaatgga agagatatac atacttaatg tactccaata tttactagga tattttgaga
     7261 tttatatgtg ttttgagata ctccgaaaag tttataaaaa ggaaaataca aagataaaac
     7321 aatgttttga aatattgatt tgtataagtt tggcagtaat agaagctatt aatcgtagct
     7381 ttcgattata ttctatttta ttaattgctg ttgttataat cgtaataagt ataacgttct
     7441 cattgattta taaaatcaaa ttacgatata cattgcttca tacctcattg tattgtttga
     7501 gtttagaatt attagatcta tttatcatat ttacaatggg aatagtgtta cataaagagg
     7561 atttggggat tgttatagga agacaaaaca gtatatccag aatattggca ttgtttttgg
     7621 gaagagcttt aatgtttcta atttccttag ccatagtgag gtataaagaa cttatagata
     7681 aaaaccgcat aggatcactc gtgttgattt tgttatcgga aattatcgga gttatatatt
     7741 ttcaatcagt gtatgcaggc gattctattc ctgatttagc aaaaggatat tatatgtatt
     7801 tcgttatcat tattttagcg ataatgtttt ttgctatata ttcgatttat cgaagcgcgt
     7861 tggaagaaag taaaattatt aaattgagaa atcgaatgtt ggaacgtaat tatgaagatc
     7921 ttaaagtata ttataatgat tctcgaactt tatttcatga ttatagagcc catattactt
     7981 tgttgcaaaa atatttggaa gaaaatcaaa tagataaagc ctgtttatat ctcaatagta
     8041 ttaataaacc acttgcagaa ttggaaaaga aaatttatac aggaaatgca gttattgatc
     8101 tggtaatgaa ttataaatta tcagaactaa aagaaaagaa tattaaaata gaatatgata
     8161 ttatgccaat cgattttggc aactaccatt ttgaagaaag tgatatattt gttattttat
     8221 acaacttgtt cgataatgct atagaagctt gtgaaaatat ctacacaaga gaaaaatgga
     8281 tttatttatc attaaggctt attaataata tgtttatgct ttgtatacaa aacagctacg
     8341 aaatcgagcc taaatacgaa aatggagaac ttctaactat aaaaacagat aagcattttc
     8401 atggaattgg tatgaagagt gtgaagaaaa ttgttgaaaa atatgaagga cagttagaat
     8461 atgataataa gcaaaatata tttgaagtta gcataaccct tttctgaagg tcaaaaaatt
     8521 gtaagttaag atataatact gacaaaatct aaaaatatgg tattatttta ataatcaaag
     8581 gaggagaaaa aatgaaaaca tgttcagaaa gaaatgagca gcggataaat agtttacaat
     8641 tatcagaaag tttggaagac gaaataaagg aacttgatgg aaagaatgta gaagcaggag
     8701 atgttatttt tactacagat acatcttcat ttcttacaat agtttgctgc taaaatattt
     8761 ttaaataaaa ggagagatat taatatggaa aatgaattta ccggttttaa ttgttttatg
     8821 gaagaaagta gcgaagtagg taaggcatat attgacatga ttttgcagca ggaaaaggca
     8881 agtgcattgg ataataaaac acgtgaatta gcgtatattg ccgtgcttgc agctacagga
     8941 attatgggtg gtttgcttta tcatgtacaa tctgctaaaa agttaggcgc aagtcgtgat
     9001 gaggtaaaga gtgcaatact ggtgggatta ccggctgtcg gattgaccat tattgatccg
     9061 ttggaagccg ctcttaaagt ctttgacgga aaatcagacc aaatcctttg attaaaaaga
     9121 agaagagcct atcacatagt gatagctctt cttcttttgt ttctatagaa ttttaaaagt
     9181 tttaagatat acgaaaaatt gcccatcttg tttctgtgaa ggttattcaa taaaatggat
     9241 ccgggacagt aagaacatat ggtaaggttg aggattattc ttagaattaa gtaagtgaca
     9301 aatgggagaa ggtttgtggt ttcttcctgg aatatttgtt tttaaaagac gtttggtaaa
     9361 gtggcaatcc aattttcaat tgcttggact aatataagtt gctgttgtag aacggccata
     9421 cctgcagttg gaatttcagg tttttgctct ttggaattaa tattatcttc taaatatgct
     9481 ttcagtattt caatgttatt ttttatatca gaaaggcatt ttttttgctt atcaggagaa
     9541 agattattta tatttactat tactgcatta aaatccagaa agatgtgaat tggtttagaa
     9601 gaaatatcaa gcattaactt ctcaaattct ttctcccctg tatctgttaa agtataaata
     9661 gccttttctg gcatttttcc ttctttaatc gtagttcctt ttataaggcc tttttcctct
     9721 aattgaagaa cttttttata tatagaaggg gtactaattt ttacccattt ggatatatta
     9781 cgatattcta caagtttttg aatatcataa gcgcttaaag ctgatgtctt taacatacct
     9841 aatacaatta aatcaatggt tgccatgctg acctcctatc cttgacatat actatatatt
     9901 atagtagtat agttattggt ttggttataa attatactac tataatttta cggtgtcaat
     9961 acaaatagaa aataacaaat gatttattgg gtgaatataa atgagagaac gctatttatt
    10021 tgaaagaaaa tatataagaa aagataatga gttgaaaatt ccttctaaat gggaaaaatt
    10081 aataggagaa gatacagtta agatactttg caaagagtat aaagagattt cttctttttt
    10141 ttctgaaaat actcaatatt atgaacagga agctccctca aatgttgagt atatggaaat
    10201 tttagaaatg tatttagcag ggagttataa aagcgaaatc attatagaaa atacaatgaa
    10261 agataaattg ttttttacat tttatatacc attttttaaa ctagctcgat attattcaag
    10321 aagaaaatat ggagatattt tagaaaaata tttttctaaa ggaatttatg aggagttata
    10381 ttcggcctta gcttgcgtgg caaccagggt tttagttaat gaaatacagt ttcttgaaaa
    10441 taaattggta ggaaagaacg caaatgaaaa atattctgca tatgttgaaa tgtatttaag
    10501 taatgatgaa tatatagagg agctttttca gttttaccct ctgttattaa gatgtatttt
    10561 agagaaaatt tgtagtgtcg tagagtttta tcatcaattg atcagtagat gggaaaaaaa
    10621 tgtaatagaa ataaaaaaat gtataaatat agataatacc gagattacaa aaattaagaa
    10681 agtaggggat aatcacagaa atggaaagca tacggtgaaa atttttttga aaaacggaaa
    10741 tgctgtattt tataaaccaa gaaatttgag gatatcaaaa atttattatg aatgcttaaa
    10801 tatattatat gaatatgtag gattgtcatg ttttaaatat agaatagcag attttggaga
    10861 gtacggttgg gaagaagaaa taaaatatca aaaatgtaaa aataaagatg aagtaaaaaa
    10921 ttattatgtt agaatggggt gtcatattgc actgagttac atattagata ttcaggattt
    10981 ccattatgaa aacttgattt ctcatgggga atatcctgta tttatagata ttgaagtgct
    11041 ctgtggacat atcaaaaaaa attatattcc gttgaccgct aacgagaaag caaaattatt
    11101 tgtagaaaat tcagtattag gaagtgggat tttaccaagg ggaaataagg agatggatat
    11161 attttgtgct ttaagcggaa aaggcggaat aaaaactggg agaaaaagat tgatcctgat
    11221 aaattccaaa acttcagata tgaaatttgt atacaaagat gcaaaaacga agaaaggata
    11281 taatagtcca cagataaatc ataaagaata tagatataat ggatttgtag atgagatttg
    11341 tctgggattt aggaaaagct atgaatatat ctggaaaaat aataagattt ttgagggacg
    11401 atttcaaaac tttagttcca gaatgttgta taatcatact caaaactatt ctaaacttat
    11461 tcaattatca tatcacccta tgtttatgac agatggagga gaaagacagc taatcctttc
    11521 aaaaaatttc ttcttccata tacgaattaa tccaaaaaat ggaaaagatt tatttgaatc
    11581 agagctatat gctatgctta aaggagatat tccttacttt agttttttat cgaataaaaa
    11641 agaattgtat atggataatc atcaaatgat caaagaatat tttaccatta caccagagca
    11701 gtatattaga atgcggatta aatcattatc tagtcaggat ttatatattc aacaatattt
    11761 attaaataac gctataaaag gatcaacagt tcatttggaa aatcgaatgg attatatgca
    11821 tgatacaaat ttttctgtta ttaaaatatg caaacagatt gctgattatc ttatgaaaat
    11881 agggataaag aatagtttaa aaacagatat taattggatt atttccttaa ctggtaccat
    11941 acatatatca gatatgtttt tatatgaagg aattgctggc atgatagttt tttttgcagc
    12001 attaaatcaa gtagcaccaa caagagcata tttagaagta cagaatattt tattgaataa
    12061 gctgctagaa tatacaatga ataattcttc ttcaaaggcg tattcaggtg cattttgtgg
    12121 tgaggcatct attatttata catatttggt attatataag ataagcaacg aagaaaaata
    12181 tataaaatat gcaaaaatac atgaaaataa gttgtttgct agtttggaaa tagataggat
    12241 gggagatttg ctatatggta atgccggtgc tgtcataata tatttaaata tgtatgaatt
    12301 aacaatggat aaaaaatata ttttgcgtgc tgaaattgcg gcgaattata ttttgaaaaa
    12361 tttgaaagaa aagtatagca tatttaataa tattgaaggt aataaaattt ctcggctgga
    12421 tagggggatt gcacatggag gtagcggata tagtatttgt tttacaagat tatttggaaa
    12481 aacaaagaag aggaaatatc taaacattgc attggagcta ttaaagtatg atattaaaag
    12541 aaataaaaaa gagaatcaaa gaagtagaaa gatatattgg tgtcatgggg cagcaggaat
    12601 agtattggcg cagcaagaaa tattaaaata tattgaagat ggttcatatc agcatatttt
    12661 tgaagattat cagacaaaaa ttagcatgat agaaaataat tttaatatag aactggatag
    12721 tttatgctta tgtcatggga ttttaggaaa tattatgatt atagaacaat taacaggaaa
    12781 aattccgtgt gtaccttgga caagcactct gagtaaatta aattatttta taaaaaaaaa
    12841 tctgtggaca aatttagaaa atggtaatcc aggattcatg atgggattgg caggaattgg
    12901 atatgcagtg ctgtatttag atgaaaatac aaaaaaattt cctaatattt taaaactaga
    12961 actctaaaaa actcttcaag aaacaagaaa atttcttgac tactactata aattatagta
    13021 ttataataaa tgtcactata atttatagta ttagaaaagg agtggaaaaa tgaaaggaca
    13081 taacaaaaaa atggaattat tagggagtgc accgattcca aaagcgttat tggcaatggg
    13141 aattccaact atgataggaa tgatgatcag cgcaatttac aatttggtag atgcctattt
    13201 tgttggaagc ttgggaacga gccaaatggg tgcgatttca gtaacgtatc ctttaagtca
    13261 ggtgattgtt gggttaggac tattgtttgg taatggcgca ggctcatata tttctaggct
    13321 gctaggacgt gggaataatg atgatgctaa aaaagttgcg agtacagcct tatacagtgg
    13381 tcttttactt ggaattattt tcataattgg cacgttagct tttcttgagc caattctgaa
    13441 gtttcttggt acaacagaaa gtatcatgcc atatgcgatt aaatatgcaa gaatttttat
    13501 tgctgcatct atttttaata ttttcaatgt gatgatgaat aatattataa caagtgaagg
    13561 tgcggctaaa atatctatgt ttgcaatgtt gtcaggcgca ttattaaata tgattttaga
    13621 tcctattttt ataaacgtat taaatatggg cgttacagga gctgctattg cttcagctat
    13681 tggacaggct ctttcaacag ttgtttttct ttcatatatt cttatgaaaa aaagtatttt
    13741 tacatttaag attaaagatt gttgttattc taaggaaaat atgaaggaaa ttttgaagat
    13801 aggagtacca acattagtat tccagttatt gacaagttta tcaataattt taattaataa
    13861 tcaggccaat gctttgagtg taacacatac aaaagaatat gtagattcag taattgccgg
    13921 aatgggagct gtaacaagaa tagtttctat gggaagttta atggtatttg gatttattaa
    13981 aggttttcaa ccgattgcag gatacagtta tggagcgaaa aattttaaac gtctaaatga
    14041 atcaattaaa acatctattt tgtggtcaac agtgttttgt gcgctttttg gattgatatt
    14101 aattttattc cctgcaacaa ttatttctaa atttacagca ggagatatgg aacttgttag
    14161 aatagggcag gcttcactca gagcaaatgg attttctatt atgctttttg gattttatac
    14221 ggtgtattct tctctatttc ttgccttagg taaaggttta gaaggattta ttttgggagc
    14281 ttgtagacaa gggatttgtt ttgtaccaat tatcttgtta ttgccgagtt tggtaggaat
    14341 aagtggtatc ttatatgcac agccaattgc agatcttatt tctgcaatta tcacagtgtt
    14401 tatggccata aatttacaca aaagtttgga aaaggaaaga ctttcatata ttaaaaatgt
    14461 agaataatga tagactatgc cttattatta aaaaattgag aattaataaa aattagcagg
    14521 atataatttc ccatagttat atcctgctaa ttttttgtac aaataataaa tataccatat
    14581 acaaaataga gtaaaatact ttctctttaa aaaatttcat taatttttgc tacgagaata
    14641 aatgagtatc ctgaatgatt tttcaacacc agtctggtga tataaaaatc atgtttgagg
    14701 atcatttttt gcgttctaaa tttttatgaa gaaatggctc aaggttgcta tatagtgcag
    14761 atatgataag acatggatat tcatctcata taaatgtatt aatgattaag tacaaaaagg
    14821 cgatttttga gtattagaat tttgattata aatttccgga tctatgattt cgagttatca
    14881 aatattcaat aaaagggtga caatgtaaag tgttttatag acacaataag ttttttcatg
    14941 aaaaggacaa tatattgcag attaggacat ttttacctat atataaaaaa atagtgatat
    15001 tttttagtgg acatatagta ttgttcaaag aaaactattc agagaaatat atgggaagag
    15061 gtaaaaaaat gtctaaagta ttatttttga atattccttc acatgggcat ataaacccaa
    15121 cattaggttt ggtggaagga ttagtgaaac agggagacga ggttttatat tttacgacag
    15181 aagagttcag aaagaaagta gaaagtatgg gtgcaacatt tataagctat ggctcgaaat
    15241 ctgatttttt tgttcctaaa aataagaaac caggaaaatc aattcttgat gatttgctga
    15301 atagaataga tgaggtcctg aatagagctg atattatcga atatatttta aaacaaatac
    15361 aaggaatgaa atttgactat attatctatg gctcaatgtt tccatatgga aatgtaatat
    15421 ctcagatatt aaacatcccg gctatctctt cttttgccgt atttgcgaaa ccaaaagttt
    15481 ttatggaaaa aggaaatgaa gagtttataa aaaatcataa agctacggac acatatcaga
    15541 aactctatat gaaattagaa actttatatg gggtacagat gccccccatg ttagatctgt
    15601 tttttaataa aggggaatta aatattgcat atacatctga attatttgtt tctaacataa
    15661 aagaagaata tgatgatagt tttcttttta ttggtccacc ggtttatgat agaaaagaaa
    15721 aaattgaatt tccatttaaa aaaataaacg gtagaaaagt aatatatatt tctttaggaa
    15781 cagtatttaa tagtattgac accaaactgt atgaaacgtt ttttaaagca ttttctgact
    15841 atgatgggat agtcgtaatg agtgcattta aaatggatat atcaaaattt catataccag
    15901 agaactttat tgtacaaaat tatgtaccac aatcagaaat gcttaaatat gtggaaggag
    15961 caataactca tggaggaatg aatagtacaa gtgacttaat atataataat gtaccatttg
    16021 tgacaattcc tataggtgct gatcaaagat atattgctag tagagtttca gagctaggag
    16081 ctactatttg tttaaataaa gataatatat ctccccaatt attatcggac tccatgaaaa
    16141 gagtaattac ggaaagaaaa tataaagaag cggtagaaaa aatttctatt tcttttaaag
    16201 atgcaggagg atataaaaag gctttaatgg agataagaaa atttaaaatt ctacatagta
    16261 tagaataaat aaggtaaggt gttacgtatg caaaaatatt cagaagatct tacactagcg
    16321 catgaatact acagagaaca ggattataaa aattgtttaa aagtatatga tatattgttt
    16381 cataaaggag agcagctttc aataggaaat ctaaaagaat acgcaatttc tctgcaaaag
    16441 aatatgagat attttgaaag cattgaaata gcaaggaaaa ttttggataa aaaaagagta
    16501 gatatagata tatttttaaa catgtgcatt tgtttgggaa aaatcggaaa atattctgat
    16561 gcgcttgagt attataataa aatcttaaaa ataaataaaa attataatat tcagattggc
    16621 tattatgcat atttgttagg acaagtggga aaaaatgaaa tggcagattt ttattataaa
    16681 attgctattg atatagagcc cgataatgca tggtatataa gtcattacgc tttttttctt
    16741 caaagaataa aagagtatag tcggtcagaa tattattata aagtagcctt aaacaaagat
    16801 aaaaataaca gttgggtatc aaaacgttac gcatattttc ttaaagaatt aaaaggaaaa
    16861 gaaaaagcat attcctatta tgagcagttg tttgtcgaga atccttataa ttataactat
    16921 tatataaatg cagcagaatt agcatttata tcaaatgata tggaaaaatc tttaaggtat
    16981 ttggaaaaag caaactctat taataaacct aaagttatgg aaattatact tcgattttat
    17041 tgggcaatat attatatttt gtccgatgat ttgaaagact tcgagaaaga agcattagca
    17101 ctaaaatctt tgcgcagaca atatacagag tttattcata gagatttgac agatctcagt
    17161 ttttatattt caaacaattt aagtgagatt aaaaaacaaa aatatgaata tatttctagt
    17221 attttgtata agggggaata gcagtatgaa aataatagat cttagtttta atgttgaacc
    17281 aaatctttct gagcctatgt caatcaaaat aaaaacaaga ccacattcag ggggctctaa
    17341 atttggaaga aaaataatat ttatgggaaa acgtagtttg aaagataagg caatggcagt
    17401 gattcattat atgtcaggga aagaacgtat aactaaaaaa agctttcctg atcaagagtt
    17461 tatcaacgaa caaaggattt cattgtctgt tcatacagga acacatttag atgctccttc
    17521 acattttgga acaagatgtg aaggaaaaaa acctaaaaca atagatgaaa taccattgga
    17581 atggtgttat ggaaatggag ttgtattgaa tttttgcaat aaaggtccat gtgaagagat
    17641 tagtgttgaa gatgtaaaaa aggagttaga aagaattgaa tattacattc aagaaaacga
    17701 tattgttctg ataagaacag atacggataa aaagtggggt aagccaaatt atttttatga
    17761 agctcctggc atgtcaagag aagcaacaaa atttttagtt gaaagtggtg tgaaaataat
    17821 aggtatagat tgctattcat tagatagacc attcatggct atggtaaagc agtattatag
    17881 aacgaatgac aaaaaatgct tatggccggc tcatttttat gggcgagaaa aagaatattg
    17941 ccatattgaa aggcttacaa acttagataa gatcccaatg aattatgggt ttaagttttg
    18001 ctgcttccct attaaattaa aagaaatggg agctgcatgg gttagagcgg tagctattat
    18061 tgaatagtga gatttaactg attattcagt taaaatatat aaaaatggag gtataaaaat
    18121 ggaacaaaaa atttacgaaa ttttaaaaga gaggtttggt attgaagaca caattaactc
    18181 agatacagat ttagttaatc aattgggatt tgagtccatt tcattagtag agttagcaag
    18241 tgtcttatca aaggaaactg gcgttaaagt tactcatagt caagcaataa aatggacgac
    18301 agttaaatct attctgtcaa cacttgctgc aaatagtaaa gataacaatg cataaggagg
    18361 ttttttatgg gatatacagt taattctatc ataataaaaa aagagatgaa cgaactgttc
    18421 gagattatta atgatgttag aaattggccg gaattacata actatcaaga tgtaaaaata
    18481 cttgaaaaag aggaattgct agatggaagg agaaagattg tttttcaagt tacggggaat
    18541 aaagaagagg aaccggttga aatttggaca tctcagagaa ttatagatgt tactaatatg
    18601 tgtgcacgag gggtaagact agagcctatg tacccattta gacattggat acttgatgtt
    18661 gttttatcag tagaaaaaga aggaacaaaa atgacttgga tacaggactt tagtatggat
    18721 aaaaattcag gatttactga agaggctgtt gaagaaatga ttaataaagg tagtaagaaa
    18781 gaacttcaaa tttttaagga aaaaattgag agtggcatag ttagcagcaa gacagaatta
    18841 taataaaata tcaataaaat ggcaaggaaa gatttgtgaa ttgtgcttgg aattttttga
    18901 aaatctttta tgccatttta ttattctgta aataaagata tattataagg agattcagat
    18961 gagaagagtt gtcgtaacgg ggataggact aattacgcct ataggcatag gaaaagaaga
    19021 attctggaaa aataataagg aaggaaaaag tggtatatgc gatatgccag aactggaaaa
    19081 attcggtttt gaatctaagg cttacggtta tgtgaaaaat tttaagccag agcaattagg
    19141 attaacatta cgtgaaatta gaagaatgga taggattact caatttggag ttttatgtac
    19201 agatcaagct gttaaagatt caaaaataga tttatctaaa atagacaaaa atagagtagg
    19261 cgttaatatt gcaaatgcag tagcaggcac aaaattcatg gatgaagaat tttcagtttt
    19321 aaccaataat ggaaaagagg tggtaaatcc ggaagatata tcaccttatg catatgcacg
    19381 ctctatgcct aatacaactt caaatgaagt atcatatcgt tatggtttta atggaacctg
    19441 ttgtacaatg gcaacaggat gtacaacagg aattgattct ataggatttg cgtatgatca
    19501 aatacggtgt ggggaattgg acgtaatgat atgcggagcg gctgaggctc caataacgcc
    19561 tataactatt gctgcctttg aagcaatagg aacactttct acaaataata atccgccaga
    19621 aaaggcctcc agaccttttg atgatacaag aaatggattt gttttagcgg aagcagcagg
    19681 gatattagtt ttagaagaac ttggacatgc tttaaataga ggtgcacata tctacggaga
    19741 aattgcggga tatggttcag taaataatgc catgcatatg acaggtttaa agccagatgg
    19801 tgaggattta tcaagagcaa taaaaattgc aatagaggaa gctaatgtca caccatttga
    19861 gattgattat atcaatgctc atggtagtgg aaccaaacaa aatgatataa atgaaacagg
    19921 cgcctataaa aaagtatttg gtgagctggc ctataaaata ccgatgagta gtacaaaatc
    19981 aatgacaggt caccctcttg gtgcggctag tgcagtagaa gcaattgttt gttgtctggc
    20041 attggaaaat aattttatgc cacctacaat taattataac aagaaagatg cactatgtga
    20101 tttggattat atacccaatt gtggaagaga aaaaaattta aatgttgttt taacaaatgc
    20161 cagtggattc ggtggacttc atgcagccat gattttaaag aaatatatag actaattgat
    20221 aataattgtt attgaataaa aaggagtata cagatgaata gacgaagagt tgtcataaca
    20281 ggattgggag tgatttcacc atcaggaaat gatgtggaaa cattttggga atcgttaaaa
    20341 caaggtaaat caagtatagg cccaattacg aaatttgata caagcgattt tgatgtaaaa
    20401 attgctgggg aagtaaaaaa ttttgacatt aagaaatacg gatttccatt tatgcttact
    20461 aggcaattag atgaatttac acattatgct atggctgcaa caaagatggc tttagacgat
    20521 tctatgataa atcttgaaat ggttgataga accagaatgg gggtttttgc aggcaattgt
    20581 cttggaggag ttgggtttgg tgagaaagaa ttgtataatt tatatagaga aggttggcag
    20641 tgtgtaagtc cctatcagtc tatttcatgg ttctatactg caccacaagg acaaatctca
    20701 attttttaca aattaaaagg ttatagtaaa acttttgtag cagatagaat aagttctgat
    20761 gttgcactgg ggtatgcata tcaatcgatt atgttgaatc gtttagatac ttgtttggtt
    20821 tgcggcacag aggctggagt atttccatac ggaatgtcac tgttttcaag tagtgatgtt
    20881 ttatcaaaaa aacgagatgc ttgttattgt ccatatgatt taaaaagaaa tggaatgatt
    20941 cttggggagg gggcaggtac cttagtaatt gaggaattag aacacgcatt aaagcgcaat
    21001 gcgccaatat acggtgaaat tctttccttt agtaataatt gtgatggggt tcatcataaa
    21061 gaaaaaaata aaaatggaaa aaaatataaa gaggtaatag aatcttgcat tagaaaagca
    21121 aatatatcgt atgatgaaat tgattatatt aatttagatg gtgctgctct atgggaagat
    21181 gatgtcattg aaacaaatgt attaaaggaa atttggggaa aagaaattgg tacagtattt
    21241 ttaagctgtc ctaaatcaat gtttggaaac acttttgggg ctgctggggc attagatgca
    21301 attattaatt gtttggcaat caaaaataac acagtacctc ccacaataaa ttatgaggat
    21361 caggattcaa attgtgattt gaattataca cctaataaag ctttgcatag aaatatcaat
    21421 acagtattac aaattgcaag ggggagaggg ggaattaata gtgctatgct ccttcgtgaa
    21481 tttaaagaat agtatagaaa ttggcatgtt atagaaaaga ggttatggag agtgcctgta
    21541 ataaaaaagg agataatttt aaaaggtaca acaaaagaga tatttaaaag aatgtctgag
    21601 tatagcttta ttcaagaaat gaattcgtct gcaaatgtat gtacaaaaat tatttttaaa
    21661 aaaccaagaa tcatcagata tggtatagaa gtaaagaatg ttgggtattg ggaatctgaa
    21721 agggtattta taccagaaaa aaatgtaatt attacacagc gtaaagaacc aatgggacca
    21781 tttaaatatt tagttgttat ctatgtttta gaaaaagata atcagggaac aaaatttaca
    21841 tatattgaag aatttgacgt atgtgataat tatcaaaatg aagtagaaaa aatttattcc
    21901 gacatttcaa aaaaagtaaa tcccatttta caaaagatca cagattattt taattcggaa
    21961 catattttgc aataagtact attgataaga gggattggta aatatggaat aataaaaact
    22021 cttgtattgt agatgaagca atacgagagt ttttatacat aagagtatag gaggttcgtt
    22081 atggcaaaaa atattgcatt tgtttttccg ggacaaggtg cacaatattc tggtatggga
    22141 aaagattttt ataatcaata tgaaaaagca aaacaaattt atgattatgc atctgaaatt
    22201 tgtaatatag atgtaaaaaa aatctgtttt gatagttctg acagtagaat tcatgaaaca
    22261 aaatatacac aaattgcaat ttttactacg tcattagcaa ttttagaatg tgtatatgga
    22321 atgggtgtca cttcaaatgt taatgctggg ttaagcttag gtgagtatac tgcattggca
    22381 gcatcaaatg tgattgatat aaaagactta tttttattag tcaaaaaaag aggaaaatat
    22441 atgcaagagg ctttcccgac aggcggtgca atggctgcgg ttattggcct ttctgaaaga
    22501 gaggtggtgg caatttgtaa tcagatgaat ggtaatatat acattgctaa ttataattgt
    22561 cccggacaga tagtcgtaac aggggaaaag gctgtagtgg aagcatcgta tgaaatattt
    22621 caaaaaaaag gagcaaagat ggttttaccg ttaaatgtta gtggaccatt tcattcgcca
    22681 ttattagaaa cggctaaaaa gaaacttgaa attagtttga aagatgtaca aattaataat
    22741 tttatcattc cctatgtatc aaatgttaat gcaaaatata ttaattatag ttgtgatatt
    22801 aaatcgttac tttctgagca aattgtttct tctgtgaaat ggcaacagag tataaaagaa
    22861 atgataagac aaggggtaaa tttgtttatt gaagtaggtc cgggatcaac attgacaaat
    22921 ttgattagaa aaattgaccc tggcgtagaa gtgctaaata ttcaagc
//
