LOCUS       gnlProkkaGPGAIPCF_75   11561 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GPGAIPCF_75.
ACCESSION   gnlProkkaGPGAIPCF_75
VERSION     gnlProkkaGPGAIPCF_75
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 02:01:06
            Original ID  :: gnl|Prokka|GPGAIPCF_75
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 14684
            Orig. end    :: 26245
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11561
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11365]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11365
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..11561
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11561
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             complement(154..471)
                     /locus_tag="ctg68_11"
                     /transl_table=11
                     /translation="MGKNIPKERKEGMYKAILELKSLEECFDFFEDICAMTELRSMEQR
                     FEVASMLKKEKVYTEIMSETNASSATISRVNRMLNYGTGCLGEVIDRLNQKEGSEEAKE
                     S"
     CDS             737..1156
                     /locus_tag="ctg68_12"
                     /transl_table=11
                     /translation="MTACGFLLYPLLLLCLLTKKNFAMLISFIAIPALCFLAVTIFRKV
                     VNKKRPYEKLPIQSLIKKDKKGQSFPSRHVFSIFLIATLWFCFWKPVGIFLFIAGVFLA
                     IVRVIGGVHFVTDVCAGALLGVLAGLISNYVFLIN"
     CDS             complement(1539..3425)
                     /locus_tag="ctg68_13"
                     /transl_table=11
                     /translation="MMKINIAKSAGFCFGVKRAVDTVYKESSKKNVYTFGPIIHNDEVV
                     ADLERQGVHVINDSEDFKSLSEGTIIIRSHGVSKAIYDEILNAGLDLVDATCPFVRKIH
                     KIVERESGDGRVIIIIGNNHHPEVEGIMGWCHTHPIVIENREQAEGIELDADTKISIVS
                     QTTFNYNKFQDLVEIISEKGYDINVFNTICNATEERQTEARELAKKSDAMIVIGGKHSS
                     NTQKLFEISKKECSNTFYIQTKNDLNMEDFSNIGMLGITAGASTPNNIIKEVHESMAEM
                     SFDQMLEESFKTIRNGEVVQGTIIDVKEDEIILNIGYKADGIISRNEYSNDQNLDLTTV
                     AKVGDEMEAKVLKVNDGEGQVLLTYKRLKAEKGNKRLEEAFNNHEVLKAPVAKVLDGGL
                     SVVVEETRVFIPASLVSDTYEKNLKKYDGQEIEFVITEFNPRKRRIIGDRKQLLVAEKK
                     AKQEALFAKIEAGMTVEGTVKNVTDFGAFIDLGGADGLLHISEMSWGRVENPKKVFTVG
                     EKLNVLIKDIQGEKIALSLKFPETNPWLHADEKYAVGNEVTGKVARMTDFGAFVELEPG
                     VDALLHVSQIAKEHIEKPSDVLKVGQEVTAKVVDFKKDDRKISLSIKALDNE"
     CDS             complement(3440..4111)
                     /locus_tag="ctg68_14"
                     /transl_table=11
                     /translation="MSMYSIAIDGPAGAGKSTIAKAIAEDIGFIYVDTGAMYRAIALYF
                     LRKGIDGHDRKLVAAECPNIHVTLEYDEEGKQQVILNGENVTGYIRKEEVGKMASVTSA
                     VPEVRAALLDLQRDMAKTSDILMDGRDIGTNVLPDASLKIYLTASADVRAKRRYDELKE
                     KGADCDIEQIKTDIIARDKQDMEREIAPLCQAEDAILVDSSDMSIPQVIDTIISEFKKI
                     K"
     CDS             complement(4241..5482)
                     /locus_tag="ctg68_15"
                     /transl_table=11
                     /translation="MNKVIIVGGGAAGMMAAISASKEGKKACILEKNEKLGKKLFITGK
                     GRCNITNACPADEFLTHVVTNPRFLYSTFSQFNNEDMMDYLEEIGLPIKTERGQRVFPQ
                     SDRSSDVIDALKKQCKKGGVQIYYHTEVKELLFDEEKENCVGVLLSDGKKMIGDSVILA
                     CGGFSYASTGSNGAGYTLAKQAGHKIKSIEPSLVPFEMKETWCKDLMGLTLKNIGVRIK
                     AKKKTVYEGFGEFLFTHFGVSGPLVLTASTCLGKYQKELEAGELKLILDLKASLTPEQL
                     DKRFLREFDTYRNKNISNVMERLLPKKMIPVFLEEAQIPEDKKIRDISKKERRHMIELM
                     KNFEMHITGVRGFNEAIVTRGGVNVKEINPSTMESKKVKHLFFAGEMMDLDAVTGGYNL
                     QIAWTTGYVAGKNA"
     CDS             complement(5482..6402)
                     /locus_tag="ctg68_16"
                     /transl_table=11
                     /translation="MEYYEIYLILQNRWKNRVEHLNLLQRIEKKSSEFSKGQRRLAQYI
                     TENYDIAAYLTASKLGKEAGVSESTVVRFAYQLDYEGYPELQKAIQVIVKTNSNSIQRM
                     SLSSKRYQEKGVLKSILYTDSERLRDTIQSGVDEEEFNRSVMLINDARRLYILGARSAA
                     YLAGLMGYYFKMMFDNVIIVDANSTSETLEQIYDISDKDVMMGITFPRYSKRTICALQY
                     AKNHGAKTIALTDNMQSPIVEYADCKLIAKSDVMTIVDSLVCPLSVVNAMVTAIALLRK
                     DDVEKRLMALEELWNEYDVYNRSLL"
     CDS             complement(6549..7106)
                     /locus_tag="ctg68_17"
                     /transl_table=11
                     /translation="MPDLGAERVDKVKKLEDYVINIPDFPKPGIIFRDITSILRDPEGL
                     KLSVHELMHCLEGTEFDVVVGAESRGFLFGMPLAYNKSKGFVPVRKKGKLPRETVSKEY
                     ALEYGTAEIEIHKEDIRPGQRIVFVDDLLATGGTAKAAIDLIEELGGVVVKVLFVMELE
                     GLHGRDVLKGYDVESVITYPGK"
     CDS             complement(7209..8054)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1179:hydrolase (Score: 175.4; E-value: 2.8e-53)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg68_18"
                     /transl_table=11
                     /translation="MEQEKKQPDVRLIGLDLDGTTLTSDKVLTPHTKEVLEKCLAEGIQ
                     VLPATGRVKSGIPEYLTQIEGMRYVILSNGASVLDLKEDKVLYQNCIPWERALELFDVL
                     EIYDTFYDIYALGAGWCEARFYDNVENYGIEKHIEKLVRTSRNRIDDLREWMKENKAPV
                     EKINMFFAKEEDRQRAFRELGKIEDLAVTCSLGNNLEINGATCNKGDAMLNLGKILDIP
                     IESIMACGDGNNDFEMVKMAGVGVAMKNGEESLKEVADFVTKTNDEEGVAYAIEHFCNV
                     "
     CDS             complement(8225..10000)
                     /locus_tag="ctg68_19"
                     /transl_table=11
                     /translation="MEKWFIASKRADFNKIGEIFHISPVTARLMRNRSLTTVREMQRYL
                     YGSLSDLYDSHLLKDADKGAEIIKEKIETGKKIRIISDYDVDGVSSNYILYQGLKRCGA
                     DVDYKIPDRVEDGYGINEHLIEKAAEDGIDTIITCDNGIAAAEQIAYGNSLGLTLIVTD
                     HHDIPFQRQEDGSISYNLPSAAAVINPKQKDCPYPFENICGAVVVYKFIQVLYDLFGID
                     RRESEAFLEIAAMATVCDVMPLCDENRIIVKEGLRRIQHTNITGLQALIEANHLEEKKI
                     SSYHFGFILGPCINASGRLTSAKDALELLLCEDKELCRQKAEALTQLNAERKEMTANGV
                     KAAKEYLESTGHANDKVLVVYLPNCHESIAGIIAGRMKEHYHKPVFVITRTKEGLKGSG
                     RSIEAYHMYKEMNKIKECFDKFGGHPMAAGFSMQEDRLEEFREKLNANATLTEDDFAEK
                     VHIDVALPISYLSESLINEFELLEPFGNENTKPLFAQKDLYIKGMRVLGTTGRCLKLFL
                     SDANGTSIDAMYFGESDGFLEELISFCGKEEAQRIQKGLSHHIWMDVTYYPQVNEWRGQ
                     KNIQIVIQNYRFKNL"
     CDS             complement(10001..11365)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_20"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 2.3e-33,
                     bitscore: 104.9, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 5.3e-16, bitscore: 49.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 4.5e-14, bitscore: 43.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.4e-20, bitscore:
                     63.3, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHQYKNNGYNIVMDVCSGAIHVVDDVTYDVIALYEEKSLEEIEN
                     ELSYSKEDIEEAYKEVTSLKEEGLLFTEDIYEDYIKEVKSRKTVVKALCLHIAHDCNLA
                     CRYCFAEEGEYKGHRELMSAKVGKAALDFLVANSGNRHNLEVDFFGGEPTMNFGVVKEV
                     VEYGRSLEEKHNKHFRFTLTTNGVLLNDEIMEFANKEMDNVVLSVDGRKEIHDYMRPTR
                     NGKPSYDLIMPKFIRFAESRHQQKYYVRGTFTNRNLDFSKDVLHLADLGFEQISMEPVV
                     GQPEEPYAIQEKDLPQIFDEYDRLAKEMIKREKAGKGFNFFHFMIDLTGGPCVAKRLSG
                     CGSGTEYLAVTPWGDLYPCHQFVGEEKFLLGNVFDGIKRTDICDEFRSCNVYTKKKCKD
                     CFARFYCSGGCPANSYNFHGTIDDSYDLSCDMERKRVECAIMIKAALADTEGEEE"
     CDS             complement(11453..11560)
                     /locus_tag="ctg68_21"
                     /transl_table=11
                     /translation="MNLPRLGSPTSTGGGGCHCKLKILYTGMFCIIYLF"
ORIGIN
        1 atataagcct cttgccaatg ccttattacc taacattaat tgtttcatgg taaaatatcc
       61 tttctattgt ttattgttcc tttttataga aagatacgac cgtcctgtac agtcgcatct
      121 aagtatatct gacgttgtaa cacatttaaa aaactaagat tctttagcct cttcgcttcc
      181 ctctttttgg ttcagtctgt caattacctc tccaagacag cctgttccat aattaagcat
      241 acgatttaca cgactaattg tagcagaact tgcgtttgtc tcactcataa tctccgtata
      301 aactttttcc ttcttcaaca tacttgcaac ttcaaagcgc tgctccatag accgaagttc
      361 agtcattgca caaatgtctt caaaaaaatc aaaacattct tctaaacttt ttaactccag
      421 aatagcctta tacatgcctt ctttacgttc ttttggaata ttttttccca taagatgttc
      481 cttcctttac gaaatataat cttatgatac catctttttt tgatttcgta aataaaaagt
      541 ttaatgtgtt aaagagattt tcctttaaac aacaaaaaca ctataataat tcccttgact
      601 cgctttttat gctatactta atctatcttt ttgataatga ggtttattta tgaatttaga
      661 acagtataca aaaatcaata attttttcat cagacactcc actgcttttt cattattact
      721 cacggcaaat cgattattga ctgcctgtgg ttttctcctt tatccattat tattactatg
      781 tcttttaaca aaaaagaact ttgctatgct tattagtttt atcgctatcc cagcactctg
      841 tttcctggca gtaaccattt ttagaaaagt agtgaataaa aagcgtccat atgaaaaact
      901 tccaattcaa tccctaatta aaaaagataa aaaaggccag tcttttccaa gccgccatgt
      961 gttttctatc tttttaatcg ctacattatg gttttgcttt tggaaacctg ttggaatctt
     1021 tctttttatt gctggtgtct ttcttgcgat tgtcagagta attggcgggg tacatttcgt
     1081 aactgatgta tgcgccgggg cactcctcgg ggtgctggca ggattgattt ccaactatgt
     1141 ctttttgata aattaaagtg agaattgcag aaatctaatt cctgcttttt taaatgtgga
     1201 cttaaaaatg ctttctatat aaattttcac ataatatata ttatacttat aagaagtttt
     1261 atttatagca aaattatata aaatgccagt gaaacattaa ctataacgaa gaaaattttc
     1321 cacccactcc catcctcttc tggagaatcc tcaaatcctc cacagcggaa tttgcgccaa
     1381 agtcagaaaa tgaaaaagac ttataatagc agatgtgacc tcggagcaag tgttggatgc
     1441 gagcccttaa gcgaacattc aacacgccgc gactaaagtc acaggtgcta ttataagtct
     1501 tttttatttt cgtctaccta gccaaattcc gctaaatatt attcgttatc taaagctttg
     1561 atgcttaagc tgatcttacg atcatctttc ttgaaatcta caactttagc tgtaacttcc
     1621 tgacctactt ttaatacatc agatggtttc tcgatgtgct ctttagcaat ctgagaaacg
     1681 tgaagtaatg catctacgcc tggctctaat tcaacgaatg caccgaagtc tgtcatacga
     1741 gcaactttac cagttacttc gttacctact gcgtattttt cgtcagcgtg aagccatggg
     1801 tttgtttcag ggaattttaa ggataatgca atcttttctc cctggatatc tttgataaga
     1861 acgtttaatt tttcacctac tgtgaaaact ttcttaggat tctcaacacg tccccagctc
     1921 atttcggaga tgtgaagaag tccgtctgct ccacctaaat cgatgaatgc accgaaatct
     1981 gttacgttct ttacagttcc ttctacagtc ataccagctt cgatttttgc aaacagtgct
     2041 tcctgttttg ctttcttctc tgctactaaa agctgcttac ggtcaccgat gattcttctc
     2101 ttgcgagggt tgaactctgt aataacgaac tcgatttcct gtccgtcata tttctttaag
     2161 ttcttctcgt aagtatcgga tacaaggctt gcagggatga atactcttgt ttcttccact
     2221 acaacactta aaccaccatc aagaacttta gctacaggag cttttaatac ttcgtggttg
     2281 ttaaatgctt cctctaatct cttattacct ttttctgctt taagtctctt atatgttaag
     2341 agaacctgtc cttcgccatc attcacttta agaactttag cttccatctc gtcaccaact
     2401 ttagcaactg ttgttaagtc taaattctgg tcgttggaat attcgtttct tgaaatgata
     2461 ccgtcggctt tatatccaat atttaagatg atttcatcct cttttacatc gataatagta
     2521 ccctgaacta cctctccatt tctgattgtc ttaaaacttt cttccagcat ctggtcaaaa
     2581 ctcatttctg ccatgctttc atgaacctcc ttgataatat tatttggggt tgaagcccct
     2641 gcagtaatac cgagcatccc gatattagaa aaatcctcca tattcaaatc attttttgtt
     2701 tgtatataaa aagtattact acattctttt ttacttatct caaaaagctt ttgagtattc
     2761 gaactgtgtt tgccaccgat tactatcatc gcatcggact tcttcgccag ttccctggct
     2821 tccgtctgac gctcctcagt cgcattacaa atcgtgttaa aaacatttat atcataaccc
     2881 ttttctgaga taatttcaac taaatcttga aacttattgt agttaaatgt cgtctgggac
     2941 acgatagata tcttcgtatc agcatctaac tcaattcctt ctgcctgctc tcgattctca
     3001 attacaatcg gatgcgtatg gcaccaaccc ataatccctt ctacttcagg atgatggtta
     3061 ttgcctataa taatgattac tctgccatcc ccactctccc gctcgacgat tttatgaatc
     3121 tttctcacaa aagggcaggt cgcatccact aaatcaagac ccgcattaag gatctcatca
     3181 taaattgctt ttgacacgcc gtgagaacga ataataatcg ttccctctga aagagacttg
     3241 aaatcttcac tgtcattgat gacatgaacc ccttgtcttt ccagatctgc gacaacttca
     3301 tcattgtgaa tgatcggccc gaatgtataa acattcttct tagaagattc tttatacacg
     3361 gtatctacag ctctctttac tccaaaacaa aagccagcag attttgctat gttaattttc
     3421 atcatttact ccggcaatat tattttattt ttttaaattc ggagataatc gtatcaatca
     3481 cctgcggaat tgacatatca gaagaatcta ccagtatggc atcttctgcc tggcataatg
     3541 gagcgatctc tctctccata tcctgcttat ctcttgctat aatatcggtc ttaatctgct
     3601 cgatatcaca gtctgcacct ttctctttca attcgtcata acgtctcttc gctcttacat
     3661 cagcagaggc cgtcagataa atcttaagag atgcatctgg caggacattc gttccaatgt
     3721 ctcttccatc catgaggata tccgaagtct tcgccatatc gcgctgcaga tcaagcagtg
     3781 cagctcttac ttctggaaca gcggatgtca ctgatgccat cttaccgact tcttccttac
     3841 ggatatatcc ggtaacattc tcaccattta agataacctg ctgtttccct tcctcgtcat
     3901 attctaaagt tacatgaatg ttaggacatt ctgccgcaac gagcttcctg tcatgtccat
     3961 caataccttt acgcaaaaaa tataaagcga ttgcccggta cattgctccg gtatctacat
     4021 atataaaacc tatatcttct gcgattgcct ttgcaatcgt gctctttcca gctcctgctg
     4081 gcccatcaat tgctatactg tacatggaca tttcctccca ttcttttgaa acctgactgc
     4141 gtatacagtg atttcacttt tacctacact tgattagtgt aacatatttt tccgaaaaaa
     4201 aaaactattt ttttataatt ttttaaattt tacgttttct ttacgcattt ttgcctgcta
     4261 cgtagcctgt tgtccatgca atctgcaggt tatagccgcc tgtgacagca tctaaatcca
     4321 tcatttctcc ggcaaaaaat aaatgtttta cttttttaga ctccattgta gacggattaa
     4381 tttcttttac atttactcct cctctcgtga cgattgcctc attaaagcca cggactcctg
     4441 tgatatgcat ctcgaaattc ttcatcagct caatcatatg ccttctttct tttttgctga
     4501 tgtctcttat ctttttatct tccggaatct gtgcttcttc taagaaaaca ggaatcattt
     4561 tctttggaag aagacgttcc atcacattag aaatattttt attacgataa gtgtcaaatt
     4621 ctcttaaaaa acgtttgtct aactgttccg gggtaagaga ggcttttaaa tcaagaatca
     4681 gttttaattc gcctgcctct aactctttct gatatttgcc aagacaggta cttgccgtaa
     4741 gaacaagcgg accactcact ccaaaatgcg taaagagaaa ttctccaaat ccttcataaa
     4801 ctgtcttttt ctttgctttg atacgcaccc ctatattctt taaagtaagt cccatcaaat
     4861 ctttgcacca cgtttctttc atctcaaatg gaactaaaga tggctctata gacttaatct
     4921 tatgtcctgc ctgctttgca agtgtatatc ctgctccatt ggaaccagta gaagcgtagg
     4981 aaaagccgcc gcaggcaagg ataacagaat ctcctatcat tttctttccg tcagacaaaa
     5041 gtacaccgac acagttttct ttttcttcat caaaaagcag ttcttttact tctgtgtgat
     5101 agtaaatctg taccccgcct tttttacact gtttctttaa tgcatcaatt acatccgaag
     5161 accggtcgga ctgtggaaat actctctgtc ctctctctgt ctttatcgga agaccgattt
     5221 cttctaaata gtccatcata tcctcattat taaactgcga aaatgtactg tataaaaatc
     5281 ttggatttgt taccacatgg gtaagaaatt cgtctgccgg gcaggcattt gtaatattgc
     5341 atctgccttt ccccgtaata aaaagcttct tgccaagttt ttcgttcttt tcaagaatgc
     5401 aggccttttt cccctcttta gacgcagaaa tggcagccat cataccggct gcccctccgc
     5461 ctacaataat tactttgttc attatagtaa actcctgtta taaacatcat actcgttcca
     5521 gagttcttca agtgccataa gacgcttctc tacatcatcc ttacgaagca atgcaatcgc
     5581 tgtaaccatc gcattcacca cacttaacgg acatactaaa gaatccacga ttgtcattac
     5641 atcactcttt gcaattaatt tacaatctgc atactctaca attggagact gcatattgtc
     5701 ggtaagtgcg attgtcttcg ctccatgatt cttcgcatac tgaagcgcac agatggttct
     5761 ctttgaatat cttggaaaag taattcccat cataacatcc ttatcactga tatcgtaaat
     5821 ctgctctaat gtctcggacg tgctgttggc atctacgata attacattgt caaacatcat
     5881 cttaaaataa tatcccatca gaccggcaag ataggctgca cttctcgcac ctaaaatata
     5941 taatcttctt gcatcattga taagcataac ggatctgtta aattcttcct catctacacc
     6001 gctctgaatc gtatcgcgaa gcctctctga atctgtatac aaaatactct ttaatacacc
     6061 tttttcctga tatctttttg aggaaaggga cattctctga atggagtttg aatttgtctt
     6121 tacaataacc tgaattgcct tctgcagctc tggatatccc tcgtaatcaa gttgataagc
     6181 aaaacgaacc actgtagact cactgactcc tgcttccttt ccaagctttg aagcggtaag
     6241 atacgccgca atatcatagt tctctgtaat atactgagcc agtcttctct gtcctttact
     6301 gaactcggaa gacttcttct ctattctctg taataaattt aaatgttcca ctctattctt
     6361 ccacctattc tgtaaaatta agtatatttc ataatactcc attttcttct ttttgtaaag
     6421 caaaatgcag gatttaaaga aagaaattgc aaatagaaat tcaactttat aactacagaa
     6481 caatttttac acaaagagaa actgtgcttc caaaaaattc catccgcaca gtttcttttc
     6541 cttcaaaatt actttccagg ataagtaata acagactcta catcatagcc ttttaataca
     6601 tcacggccat gcaatccctc aagttccata acaaacagaa cctttacgac aacgccacca
     6661 agttcttcaa tcagatcaat cgcagccttt gctgttccac cagttgctaa aaggtcatcc
     6721 acaaatacga ttctttgtcc tggacgaatg tcctctttat ggatttcaat ctctgctgtt
     6781 ccatactcta aagcatattc tttgcttaca gtctctcttg gcagctttcc tttcttacgg
     6841 acaggaacaa atcccttgct tttattgtaa gcaagaggca taccaaataa aaatccacgg
     6901 gattccgctc caacaactac gtcaaactct gttccctcta agcaatgcat caattcatgt
     6961 acgctaagtt tcagtccctc cggatcacgt aaaatagagg taatatctct gaaaataatt
     7021 cccggctttg ggaaatctgg aatattaatg acataatctt caagtttttt cactttgtcc
     7081 accctttctg cccccaaatc aggcataaaa ctattaagca cagactttta tcttcgcgct
     7141 ttttcttctt atgattaatt ataacagatt ttttatgtaa aaaacaacag aaaaacgttt
     7201 atttctactt acacattaca aaaatgctcg atagcgtatg ctacgccctc ctcatcattt
     7261 gtctttgtca caaaatctgc aacctctttc aaagactctt ctccgttttt catagcaaca
     7321 ccgacaccag ccatcttaac catctcaaaa tcgttattgc catcgccaca cgccataata
     7381 ctttctatcg gaatatcaag aatttttcca agattgagca tcgcatctcc tttattacaa
     7441 gttgccccat taatctcaag attattacca agagaacagg taaccgccaa atcttctatc
     7501 tttccaagtt cacggaaagc tctctgtctg tcttcttcct ttgcaaagaa catatttatc
     7561 ttctccactg gagctttatt ttctttcatc cactctctta aatcatcaat acgattgcgt
     7621 gatgtacgaa ccagcttctc gatatgtttc tcaattccat agttttctac attatcataa
     7681 aagcgagcct cacaccagcc agctcctaat gcataaatat cataaaatgt atcatatatt
     7741 tctaacacat cgaataactc caatgctctc tcccacggaa tacaattctg ataaagaact
     7801 ttatcctctt ttaaatctaa tacacttgca ccattggata aaataacata tctcatccct
     7861 tcaatctgtg ttaaatactc tggaataccc gattttactc ttcctgttgc cggtaaaacc
     7921 tgaatccctt ccgcaagaca tttctcaagt acttcctttg tatgtggagt taacacctta
     7981 tctgaagtga gcgttgttcc atctaaatct aatcctatca atctgacatc tggctgtttt
     8041 ttctcctgtt ccatattttc tccttatcta tctcttaatt catagcgatt ttgatgtatc
     8101 tctcttttca tcctcatatt attctattga ttctcgcctt atttgtcaaa ttaggatagt
     8161 tttttattaa ttgggaatct aaacagacga aaaaatatgc gaaagaagca ctaaaaaatt
     8221 tatctcataa atttttaaaa cgataattct ggatgacgat ttggatattc ttctgccctc
     8281 gccattcatt tacctgtgga taataagtca catccatcca tatatgatgt gacaggcctt
     8341 tttgaattct ctgtgcctct tcttttccac aaaaagagat gagttcttct aaaaatccat
     8401 cggattctcc aaaatacatg gcatctatgc ttgttccatt ggcatccgac aggaagagtt
     8461 ttaaacatct gcctgttgtt ccgagtaccc gcattccttt tatgtaaagg tctttttgtg
     8521 caaagagcgg ttttgtgttt tcatttccaa atggttctag taattcaaat tcattgatga
     8581 ggctttcgga taaataagat atcggcaagg ctacatcaat gtgaactttt tctgcgaaat
     8641 catcctcggt aagggttgcg ttggcattta atttttcccg gaattcttct aagcggtctt
     8701 cctgcataga aaatcctgct gccatcgggt gcccaccgaa tttatcgaaa cattccttga
     8761 ttttgttcat ttccttatac atatgatagg cttcgataga acggccagag ccttttaatc
     8821 cttcttttgt tcttgtgatg acaaatactg gcttatggta atgttctttc attcttccgg
     8881 caataattcc ggcgatactt tcgtgacagt ttggaagata tacaacaagt accttatcgt
     8941 ttgcatgtcc ggtgctttcg agatattctt ttgcagcttt taccccgtta gctgtcattt
     9001 cttttcgctc tgcatttagc tgtgtgagtg cttctgcttt ctgcctgcaa agttctttat
     9061 cttcgcatag aagaagttct aacgcatctt ttgcagaggt caaacgaccg gaagcattaa
     9121 tacacggacc gagaataaat ccaaagtgat aagaagatat ctttttttct tcaagatgat
     9181 ttgcctcaat taaagcttgc agcccggtaa tattcgtatg ctgtatccgt cgcaggcctt
     9241 cctttacgat aatacggttc tcatcacaca atggcataac atcacatact gttgccatcg
     9301 ccgcaatctc aagaaatgct tcactttctc tacggtcaat tccaaacaaa tcataaagca
     9361 cctgaataaa cttgtagaca acaaccgctc cgcatatatt ttcaaatgga tacggacaat
     9421 ctttttgctt cggattaata acggcagcgg ctgacggcaa attataagaa atgcttccat
     9481 cttcttgcct ttgaaacgga atatcatgat gatctgtcac aatcagggtg agtcctaaag
     9541 aatttccata agcaatctgt tctgctgccg caattccatt gtcacaggtg ataatcgtat
     9601 caattccatc ctctgctgcc ttttctatca gatgttcatt aattccataa ccgtcttcca
     9661 cacggtcagg aatcttataa tcaacatccg caccacagcg ttttaatccc tgatataaaa
     9721 tatagtttga tgaaacacca tctacatcat aatccgaaat aatccgaatc tttttgcctg
     9781 tttctatctt ctcttttatg atttccgctc ccttatcggc atctttcaaa agatgagaat
     9841 catataaatc agacagagag ccataaagat aacgctgcat ttccctaact gttgttaagc
     9901 tcctatttct catcagacgc gccgttaccg ggctgatatg aaatatctca ccaattttat
     9961 taaaatctgc tctttttgaa gcgataaacc acttttccat ctattcttct tcgccttctg
    10021 tatctgctaa tgcagcctta atcataattg cgcattctac tctcttacgc tccatatcgc
    10081 aacttaaatc ataagaatca tcaattgttc catggaaatt ataagaattt gcaggacagc
    10141 cgccgctaca gtagaatctc gcaaaacagt ctttacattt tttctttgtg tatacgttgc
    10201 aggaacggaa ttcgtcacaa atatcggtac gcttgattcc atcaaaaacg ttaccaagaa
    10261 ggaatttctc ttctcctaca aactggtggc aaggatataa atctccccat ggtgttactg
    10321 ctaaatattc tgttccgctt ccacagccgg aaagtctttt tgctacacat ggaccacctg
    10381 taaggtcaat cataaagtgg aagaaattaa agccttttcc tgctttttct ctcttaatca
    10441 tttcttttgc aagtctgtca tactcatcaa aaatctgtgg aaggtctttt tcctgaattg
    10501 cgtatggctc ttctggctgt ccaacaactg gttccatgga aatctgttca aatcctaagt
    10561 ctgcaagatg aagaacatct ttggagaaat caagatttct attggtaaat gttcctctta
    10621 catagtattt ctgctgatgt ctggactctg caaaacgaat aaacttcggc atgataaggt
    10681 catagcttgg cttaccattt cttgtaggac gcatgtaatc atggatttct ttacgtccat
    10741 cgacacttaa aacaacgttg tccatttctt tattggcaaa ttccataatc tcgtcattta
    10801 acagcacacc attggttgtc aaagtgaaac ggaaatgttt gttatgtttt tcttcaagag
    10861 aacgtccata ttctacaact tcctttacaa caccgaagtt cattgttggc tcaccgccaa
    10921 agaagtcaac ttcaagatta tgacggtttc cagaattggc tacaaggaaa tcaagggcag
    10981 cctttccaac ctttgcactc ataagttcac ggtgtccttt atactctcct tcttctgcaa
    11041 aacaatagcg gcaggcaaga ttacaatcat gcgcaatatg caggcaaagt gcctttacta
    11101 ctgtctttct gctctttacc tctttaatat aatcttcgta aatatcttct gtaaataaaa
    11161 gtccctcttc ttttaaagaa gttacctctt tatatgcttc ctcaatatct tccttgctgt
    11221 aagaaagttc attttctatt tcttccaagc ttttttcttc atataaagca atgacatcat
    11281 aagtcacatc atcaacaaca tgaatggcac cactgcacac atccatgaca atattatatc
    11341 cattattttt atactggtga atcacgttaa atatcccttt ctatttcttt tatagttttt
    11401 atacttaatt ttctaaaata tatttttaat ttgaagatat gtcctgctaa ctttaaaata
    11461 gatatataat acagaacatt cctgtataca atattttcaa cttacagtga catcctcccc
    11521 cacctgtaga ggtggggctt cccaacctcg gcaagtttgg t
//
