LOCUS       c00056_gnlPro..        17683 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PPMECFNC_56.
ACCESSION   c00056_gnlPro..
VERSION     c00056_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 20:42:14
            Original ID  :: gnl|Prokka|PPMECFNC_56
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17683
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17683
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4707:7683]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4708..7683
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..17683
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17683
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(17..247)
                     /locus_tag="ctg56_1"
                     /transl_table=11
                     /translation="MKKKSEGKTRKCLTLLGGRTSLLLCLSLGEFYQFNLSSCIRQQNS
                     LTAQFVSFSLANLANIFYPPPIFTIINLCLL"
     CDS             complement(450..4490)
                     /locus_tag="ctg56_2"
                     /transl_table=11
                     /translation="MRNILFTVLFIGILSLIASPISLASKSLHKANMINLSNNAIICMH
                     QDPDGYLWIGTYDGLNLYNGKDTYVYRFELNNKNSLCSNIIHKISDAEPGFLWISTSLG
                     INKFSLKERKVTESFPGYMECDLLASDSSGITLAICKENRISCYTPSSDGFRDLPREGV
                     GPQTVRTLFAGTDGHFYLLLASGILKKLTPDFSDTTFNLLSEERQFHNKPILSAFYENN
                     HIFIVDTDNKLYRQHVDGKGKEFLFDLPEMTKQYGNIIKICTFQSNVYIVFRNGNILDL
                     SQPENTINMGIGIFCLMNDKRQEILWLGTDGQGIRMFYDKPDLFGSILLKDLPINIQNP
                     IRSLYTDDDQSLWLGTKGDGIVRIQAYDTYHNKKMIPQSAITHFTTADGLSSNRVYCFQ
                     KSEYHPCIWIGTEGPGLTYYSYKEKRIKTIPQREDTTPLRYVHSICEVDDSTLWLATTG
                     NGLQKVTLHIDKAVPTIGKVQTFPLKNGKNICKEIQSMVYDNDSTLFLGSRGGYGVIRF
                     NIFNQGYEFLQTNNLRNPAIGDVLSVCQTEDSTFYAGASSGLTRIKFRGGKMRLRQFDK
                     SDGIVNDMIHGIHEGNDSCIWLSTNKGLTKYNPRNNFFHNYHQPYFSVTEFSDDAYWKC
                     PYSERLFFGGINGLVWVNKQTEPEHTYQPELSFFELQMDKQILPLYKDISRNGVTVPAD
                     VQSLTIAFVAPDYINGENYEYSYQLVNYNSSWEKLQKTNKVTFRNLPYGEYLLKVRYRN
                     DVIDSSAKEYTLPIKVLPPIYLSSLAIFTYLFIGTVLLIIATYRIHHQILKKQKQIADK
                     IKEEQKEKLYESKLNFFTHITHELCTPLTLINGVENYIQAYAATSKDKTLEKYTSVLRE
                     NVEELNGLIQEILDFRKAEDAGFSHTHIRRVSVSSLLRTQFEWFYPLSEQHQIQFKIDA
                     PKELYWNTDSVYFKKILANLISNAFKYTEDGGTVRISLHEEENFLVLKVYNTGKGIEEA
                     DMQNIFDRYRILGTMDNDDNRQNTARNGLGLFICHSLVQSLGGKIDIESEVGQYAEFTV
                     TLPFGIVEESSDDTIDEDIPVSLPSPNTDIQKPQISHTAQKETENKPMILVIDDHKDIV
                     WLITETLSSEYQVQEAYNAEEALEFLKQYTPSLIITDIMMPNIDGLELISLIKENRYTR
                     HIPLIIVSAKISDQEQAAGLNIGADAYLTKPFSPTVLLSVVNRLMTNQRELKEYFYSPE
                     SAYQYTEGQLLHQEDKEFLDAVTAIIKENVSKEGLGPELVADALNINTRILYRRFKKIS
                     TMTPSDFIKDYRLNYAAQLLVNTNMSVQEIIYNVGISNKSYFYREFARKYNMTPKEYRT
                     KEA"
     CDS             4708..6948
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_3"
                     /sec_met_domain="Gly_radical (E-value: 4.8e-45, bitscore:
                     145.5, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 3.8e-281, bitscore:
                     926.7, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFENECWDHFKGETWKREINVRDFIQSNYTPYEGDDSFLVASSE
                     KTRKVWNKLTEMFKVEREKGVYDAETKLPQGIDVYGPGYIDKENEVIVGLQTDAPLKRG
                     IFPKGGIRMVENSLEAYGYHLDPMTKEIFTKYRKTHNEGVFSAYTEEMIAARRSAIITG
                     LPDAYGRGRIIGDYRRVALYGTAILIEEKKRFLNRLDIQEITEEIIQSREEISEQIKAL
                     KAFEKMCASYGFDVTRPAQNAREAVQFVYLAYLAAVKDQDGAAMSIGRTSTFLDIYIEK
                     DIREGKLTEEEAQELVDQLIIKLRIVRFLRTPEYNDLFSGDPVWVTESLGGQGVDGRSL
                     VTRTSYRYLHTLYNLGPAPEPNLTVLWFKNAPENWKRFCAKVSIDTSAIQYENDDLMRP
                     DYGDDYGIACCVSPMKIGKQMQFFGARANLAKCLLYAINGGRDERSGVQVAPMFEPVRG
                     EYLEYDEVMAKYEQMMRWLAKVYVNALKIIHYMHDKYAYEAFEMSLHDGDVERIRATGI
                     AGLSIVADSLAAIRDTKVRVIRDERGLAVDFEREGEYVPFGNNDDRTDSIAVEITEKFM
                     EYLRQHETYRHAKPTQSILTITSNVVYGKKTGTTPDGRIGGTPFAPGANPMNGRDTKGA
                     IAALASVAKLPFQHAHDGISYTFAVSPATLGKEREVQINNLVSLLDGYFTPDGGQHLNV
                     NVFDKDLLIDAMEHPEKYPQLTIRVSGYAVNFVKLTREQQLDVISRTINHSL"
     CDS             6949..7683
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 67.6;
                     E-value: 4.7e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_4"
                     /sec_met_domain="Radical_SAM (E-value: 1.6e-32, bitscore:
                     106.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VIKGKIHSLESFGTVDGPGIRFVVFMQGCPLRCLYCHNPDTWNPK
                     GKVKYQMTPGELLTEVLRYKSFIARGGVTVTGGEPLLQPEFLKEFFRLCQEQGLHTALD
                     TSGFVCTSKAWEVLDYADLVLLDIKTLNPDLHPLLAGVKQDNTLLFLDELERRGIDTWI
                     RHVIVPGYTDNDEWLEALARYVSSYKVVRKVELLPYHTMGTYKYEQLGLDYPLKGVEPL
                     SKERLDNAKAIFSRYKPENNKA"
     CDS             7810..8460
                     /locus_tag="ctg56_5"
                     /transl_table=11
                     /translation="LLYATNIYFCKEIKNDIDQKMMNSMKTPQEIAEMISKRFYPLPDA
                     DLDSLASIIESSKAAKGELLLDNGQISKYLYYVESGLLRQFYYKNKRDITEHFSCEGNI
                     VICIASTFQREPTRLLIEALEPTVYHRISFSEFSDLLKTSLAINRLYQKILEWALMLSQ
                     EKADSWRFESARKRYLRFQQEYPEAAKRASVNHIASYLLMTPESLSRVRAGVL"
     CDS             8568..9848
                     /locus_tag="ctg56_6"
                     /transl_table=11
                     /translation="MKIEKITGREILDSRGNPTVEVDILLESGVMGRASVPSGASTGEN
                     EALELRDGDKKRYGGKGVLKAVENINTIIAPALKGMSALDQIGIDHAMLALDGTKTKSK
                     LGANAILGVSLAVAKAAANYLDIPLYRYIGGTNTYVMPVPMMNIINGGSHSDAPIAFQE
                     FMIRPVGAASFKEGLRMGAEVFHALKKVLHDRGLSTAVGDEGGFAPNLEGTEDALNSII
                     AAIKAAGYEPGKDVMIGMDCASSEFYKDGIYDYTKFEGEKGVKRTSDEQVDYLEKLINE
                     YPIDSIEDGMSENDWAGWKKLTDRIGNHCQLVGDDLFVTNVEFLSRGIKEGCGNSILIK
                     VNQIGSLTETLNAIEMAHRHGYTTVTSHRSGETEDATIADIAVATNSGQIKTGSLSRSD
                     RMAKYNQLLRIEEELGDRAVYGYKRIN"
     CDS             10069..10635
                     /locus_tag="ctg56_7"
                     /transl_table=11
                     /translation="MEPIINSQLPEFKVQAFQNGNFKTVTNEDVLGKWAIFFFYPADFT
                     FVCPTELVDMAEKYEQFKSMGVEIYSVSTDSHFVHKAWHDASETIRKIQYPMLADPTGA
                     LSRAFGVMIEEEGMAYRGTFLVNPEGKIKVAEIHDNNIGRDASELLRKVEAAQFVASHD
                     GEVCPAKWKKGEATLKPSIDLVGKI"
     CDS             10655..12208
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg56_8"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.5e-47, bitscore:
                     155.2, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLESTLKEQLKGIFAGLNANYTFDISISPAHESRQELLDLLGDVA
                     SCSDKISMRVSDGDGLEFILLKDGAKTGIKFRGVPNGHEFTSLLLAILNSDGKGKNFPD
                     ESICNRVKALNGPIHLTTYVSLTCTNCPDVVQALNAMTTLNPQIHHEMVDGAINQAEVD
                     ALKIQGVPSVFADGKLIHVGRGEFGELLSKLEAQYGINESLTEKTVKRYDVVVVGGGPA
                     GASAAIYSARKGLSVAVVAERIGGQVKETVGIENLISVPETTGTQLADNLRLHMRQYPI
                     DLLEHRRIEKVTIEGNEKVLSTAGGEIFKAPAVIVATGASWRKLNVPGEAEYIGRGVAF
                     CPHCDGPFYKGKHVAVVGGGNSGIEAAIDLAGICSKVTVLEFMDELKADQVLQEKAKSL
                     PNVEIFVSSQTTEVVGNGDKVTGIRTKDRKTGEERVIHLDGIFVQIGLAANSGVFKEIV
                     ETNRPGEIVIDAHCRTNVPGIYAAGDVSTVPFKQIIISMGEGAKAALSAFEDRVRGVLG
                     "
     CDS             12293..12643
                     /locus_tag="ctg56_9"
                     /transl_table=11
                     /translation="MDRLRKYLRILLPALFIAYLGCIIAFTHVHIVNGVTIVHSHPYHK
                     TDDGRPDHEHGYAEFQLLHQLSVLQITGAAFVAILLAAFYSFIRNLSFAPVYPDYIVPF
                     RGRRTLRAPPIF"
     CDS             12690..14999
                     /locus_tag="ctg56_10"
                     /transl_table=11
                     /translation="MNKFFIFILCLCCALTVAQATGEDRLNDSDANVFGHVLDKKTGEH
                     LPFINVLLKGTTIGTTTDNSGHYFLKNLPEGKFTLEYKALGYKTVSKEVSLKKGKTLEI
                     NVELEEDQIALDGVVVSANRAETSRRLAPTLVNVLDAKVFTTTNAVNLAQGLNFQPGVR
                     VETNCQNCGFQQVRINGLDGPYTQILIDSRPIFSALSGVYGLEQIPANMIERVEVMRGG
                     GSALFGSSAIAGTINIITKEPLRNSGELSHTLTSIGGTSAFDNNTTLNASLVSENGKAG
                     LYLFGQNRHRSGFDQDGDGFTELPKLKNQTVGFRSYLKTSTYSKLTFEYHHMNEYRRGG
                     NLLDRPPHEADIAEQLEHSIDGGGLKFDLFSKDYKHKWSVFTSAQNTDRDSYYGTNQDP
                     NAYGKTTDLTVMAGTQYAYSFDKFLFMPSDLTAGLEYSFDHLKDEMIGYNRFTNQKVHI
                     ESAFLQNEWKNKRWSFLIGGRLDKHNMMDHVIFSPRANIRFNPTEDINIRASYSSGFRA
                     PQAFDEDMHISAVGGEVAMIQRAKDLSEEKSQSLSASVDFYHRFKNGIQLNFLVEGFYS
                     SLSDVFVLEDIGKDEQGNLIKERRNGSGAKVMGLTLEGKSVLTSWLSLQAGATFQRSRY
                     KEAEKWSDDENVPAETKMFRTPDIYGYFTATLTPFKRFTASLSGTYTGSMLVQHLAGYI
                     PLDKAVETPDFFDMNIKLAYEFPLYKELKLEVNGGVQNLFNAYQSDFDQGKNRDSSYIY
                     GPASPRSYFAGVKMSF"
     CDS             complement(15173..16165)
                     /locus_tag="ctg56_11"
                     /transl_table=11
                     /translation="MTDRRTFLRNISLLTLGGIASQKVMASNPTRSIPATDAISSATAG
                     KKMGLQTYSLGQELLQDMPNGLNRLAKAGYTDLEIFGYREDTGKFGDYNPKNTTFIASK
                     DYKKMVDDAGLRISSSHLTPSLREYTKENMPKFDEFWKKATDIHAELGVSCMVQPSLPR
                     IENEDDAKVVSEIFNRAGEITKKAGILWGYHNHSNEFKRVLKAGEKPEQNPNPWAPPKG
                     TYIEELFLKNTDPDKVMFELDVYWAVMGQQDPVEWMENYPNRFKLLHIKDRWIIGDSGM
                     MNFPNIFKKAYEIGILGYYVELEGDKKGRTQFEGVEKSAAYLQAAPFVK"
ORIGIN
        1 cctgcacatc caatttttac aacaaacaca agttaattat tgtaaaaatc gggggggggt
       61 agaaaatatt cgctaaattt gcaagactaa agctcacaaa ttgggcagtt aaagagttct
      121 gctgtctgat acaagaggat aaattgaatt gatagaactc acctaaagat aaacaaagta
      181 acaaagaggt tcgtccacct aataaagtca ggcatttcct cgtcttacct tcactctttt
      241 ttttcataaa aacattaaat taaaagttaa taatgtgctt cccgaaggaa gaatacacac
      301 aagcggtttg ctttgttatt cgacagcaat attaataggt cttaacgaat tgaagagtgc
      361 tttgaaatac cgaagaagtg tcatgaaatg catatggcag attatgatac tcttttggtt
      421 gattatgaca ctatttagga atcaatgatt tatgcctctt ttgtgcggta ttctttagga
      481 gtcatgttat atttacgggc aaactcccta tagaagtatg atttgttaga aatccctaca
      541 ttataaataa tttcctgaac gctcatgttg gtatttacga gtaattgcgc tgcatagttt
      601 aacctataat cctttataaa atcactaggc gtcatggtag atattttctt gaaacggcga
      661 tataagatgc gggtgtttat attcagtgcg tccgctacca gctcgggacc gagtccttcc
      721 ttgctgacat tttctttgat gatagcggtt acggcgtcaa ggaattcctt gtcttcttga
      781 tgtaataatt gcccttccgt atattgataa gcactttccg gagaatagaa atactctttt
      841 aattctcttt gatttgtcat caatcggttc acgacggata ggagaactgt tggcgagaaa
      901 ggcttggtta gataggcatc cgctcctata ttaagtcctg ccgcttgctc ttggtctgat
      961 attttggcag atacgataat aagcgggata tgacgggtat atctattttc cttgataaga
     1021 gagatcaatt ccaatccgtc gatattaggc atcatgatat cggtgatgat aagggaggga
     1081 gtgtattgct tgaggaattc cagagcctcc tccgcattat aagcttcctg aacctgatat
     1141 tcggaagaga gggtttccgt gattagccag acgatgtctt tatgatcgtc gataacgagt
     1201 atcatcggtt tattttccgt ctctttttgt gccgtatgtg agatttgcgg cttttgtata
     1261 tccgtgtttg gggaaggaag cgatacggga atatcttcgt ctatcgtgtc gtctgagctc
     1321 tcctctacga tgccaaaagg taaggtaact gtaaattcag catattggcc gacctcactc
     1381 tctatgtcga ttttaccacc taaggattgt acgaggctgt ggcagataaa taagccgagg
     1441 ccattccgtg ccgtattttg cctgttatcg tcgttatcca tcgtgccaag gatacgatat
     1501 cggtcgaaaa tattttgcat gtctgcctcc tcgattcctt tgccggtgtt gtaaacttta
     1561 aggacgagga agttctcctc ctcatgtaag gagatacgaa ccgtgccccc gtcttccgta
     1621 tacttaaatg cgttggaaat cagatttgct aggatcttct tgaaatagac ggaatccgta
     1681 ttccaataaa gctctttggg agcatcgatc ttgaattgga tttggtgttg ctcggatagt
     1741 gggtaaaacc attcgaattg agttcgcaaa agagaggata cggatactct tcggatgtgc
     1801 gtatgactga atccagcgtc ttccgctttc cggaaatcaa ggatttcttg gataagcccg
     1861 ttcagttcct ctacattttc ccggaggact gaagtgtatt tttctaatgt cttgtctttt
     1921 gaggtggcgg cataggcttg gatataattc tccacgccat tgatcaaggt aagcggggtg
     1981 catagctcat gcgtaatgtg ggtaaagaaa ttcagcttgg actcgtatag cttctctttt
     2041 tgctcctcct tgatcttgtc tgcgatctgc ttctgtttct ttagtatttg gtgatggata
     2101 cgataggtgg cgatgatgag caaaaccgta ccgataaaaa gatacgtgaa aatggctaac
     2161 gagcttagat aaataggagg taataccttg ataggtagag tgtattcttt tgctgacgaa
     2221 tcaatgacat cgttgcgata acggactttc agcaaatatt ccccgtacgg taggttcctg
     2281 aaagttacct tgtttgtctt ttgcaatttt tcccaagagg aattatagtt gaccaactga
     2341 tacgaatact cgtaattctc cccgttgatg taatccggag cgacgaacgc aatcgttaac
     2401 gattgcacat cagccggaac cgttacaccg ttccggctga tgtccttata taatggaagg
     2461 atttgtttat ccatttgcaa ctcgaagaaa cttaattcgg gttgataggt atgctccggc
     2521 tccgtttgtt tatttaccca gactaatccg ttgatgcctc caaagaataa acgctcggag
     2581 tatgggcatt tccaataagc gtcatcagag aattccgtga cgctaaagta aggctgatga
     2641 taattatgga aaaagttgtt ccggggatta tatttggtga gacctttatt ggtactaagc
     2701 cagatacagc tatcgttccc ctcatggata ccatggatca tgtcgtttac gatcccgtcg
     2761 cttttatcga attggcgtaa acgcatcttt ccccctctga atttaatccg ggtgagaccg
     2821 gagctggcgc ctgcataaaa cgtggaatct tcggtctggc atacggaaag cacatctcca
     2881 atggccgggt ttcttaaatt gttggtttgc aggaattcat atccttgatt gaaaatattg
     2941 aaacgaatga ctccgtaacc gccacggctc ccgaggaaca gggtagagtc gttgtcatat
     3001 accatcgatt ggatttcttt acagatgttc tttccgtttt ttaacgggaa ggtttgtacc
     3061 ttcccgattg taggtacggc tttatctata tgtaaggtaa ccttttgcaa tccgttaccc
     3121 gttgtcgcta gccataatgt ggaatcatct acctcgcaaa tagagtggac atagcgtaga
     3181 ggggtggtgt cttctcgttg cggtatcgtt tttattcgtt tctctttata cgaataatag
     3241 gtcagtcccg ggccttccgt gccaatccag atacatggat ggtactcgct tttttggaag
     3301 caatacacac ggttgctgga taggccgtcg gcggtggtaa aatgcgtgat agcgctttgt
     3361 gggatcatct ttttgttatg gtaagtgtca tacgcttgta tccggacaat accgtctcct
     3421 tttgtcccga gccaaaggga ttgatcatcg tctgtatata aagaacgtat ggggttctgt
     3481 atattaatcg gtaaatcctt gagtaagata gagccgaaaa gatcgggttt gtcataaaac
     3541 atccgtatac cttgcccgtc tgttcccaac cagagaatct cctgcctttt atcgttcatt
     3601 aggcaaaaga taccgatgcc catatttatc gtgttttccg gttggcttag gtctagaata
     3661 ttgccgttac ggaaaacgat atacacattg gattggaagg tgcatatctt gatgatgtta
     3721 ccatattgtt ttgtcatttc aggcagatcg aacaggaatt ctttcccctt tccgtctaca
     3781 tgctgtcgat ataatttatt gtcggtatct actatgaaaa tatgattatt ctcgtaaaat
     3841 gcggataaga tcggtttatt atggaattgg cgttcttccg atagcaaatt aaaagtagta
     3901 tcggagaaat ccggagtcaa ctttttcagt atgcccgagg ctaataataa ataaaaatgt
     3961 ccgtccgtcc cggcgaataa ggtacgtacg gtttgagggc ctactccttc tctcggcagg
     4021 tcccggaacc catcgctaga tggggtgtag caagagattc tgttttcctt acaaatagcg
     4081 agcgtgatgc cggatgaatc ggaggccaat agatcgcatt ccatgtatcc ggggaaagac
     4141 tcggtgactt tccgttcttt tagtgagaat ttattgatac ctaaagaggt tgatatccat
     4201 aaaaagccgg gttctgcgtc ggatattttg tgaatgatat tactacaaag agagtttttg
     4261 ttatttaatt cgaaacgata tacatacgta tcttttccgt tgtataagtt aagtccgtcg
     4321 taagtcccga tccacaaata gccatccgga tcttgatgca tgcaaataat ggcattgttc
     4381 gacaaattaa tcatatttgc cttatgcaaa gatttagacg cgagtgagat aggagatgcg
     4441 attaaagata gtattcctat aaataaaacg gtaaacagga tatttctcat gtgtttgatc
     4501 cagattaact tttacgttct gtaggcaaag atagtgaata aaatggagac ttcgtgcaaa
     4561 gcatcgcatt actatcccgt ttcttcttgt atatttttaa tacctattta tagggatttt
     4621 agaggggtgt cgcaaatgtt acaggaacat gaggataaaa gttttacctt tgcggcggta
     4681 aaaatgtggt attagataag attgtttatg aaatttgaga atgagtgctg ggatcacttt
     4741 aagggtgaga cctggaaaag agagatcaat gtaagagatt ttatccagag taactatacg
     4801 ccttatgaag gggatgattc ctttttagtc gcttcttccg agaagacccg taaggtctgg
     4861 aacaagctga ccgagatgtt taaggtcgag agggaaaagg gagtttatga cgccgagaca
     4921 aaattacctc aagggatcga tgtatatggc ccgggctata ttgataagga gaatgaggtt
     4981 atcgttgggt tacaaaccga tgctccgctg aaacgtggta tcttcccgaa gggcggtatc
     5041 cgtatggtcg agaatagctt ggaagcttat ggttatcatt tggacccgat gacgaaagag
     5101 atcttcacga agtaccgtaa aactcataac gagggcgttt tctccgcata tacggaagag
     5161 atgattgccg cacgtcgttc ggctattatc accggtctgc ccgatgcgta tggcagagga
     5221 cgtattatcg gtgactatcg tcgtgtcgct ctgtatggta cggcaatctt gatcgaggag
     5281 aaaaagcgtt tcttgaatcg tttggatatc caagagatca cggaagagat catccagagc
     5341 cgtgaggaga tttctgaaca gatcaaggct ttgaaagcgt tcgagaaaat gtgcgctagc
     5401 tatggctttg atgtgactcg tccggcacaa aacgctcgtg aggcagttca gtttgtgtac
     5461 ttagcttatc tggcggcggt aaaagaccaa gatggcgcgg cgatgtctat cggacgtact
     5521 tctacgtttt tggatattta tatcgagaaa gacatccgtg agggtaagtt gaccgaagag
     5581 gaggcgcaag aattggtaga ccagctgatc atcaagttgc gtatcgttcg tttcttacgt
     5641 acgccggaat acaatgattt gttctccggt gatccggttt gggtaacaga gtccttgggc
     5701 ggccaaggag tggatggccg ttctttggta acaagaactt cctatcgtta tctccataca
     5761 ttatataatc taggtccggc accagaaccc aatttgacag ttctgtggtt taagaacgct
     5821 cccgagaact ggaaacgctt ctgtgccaag gtctctatcg atacatcggc tatccaatat
     5881 gagaacgacg atttgatgcg tccggattat ggagatgatt atggtatcgc ttgttgcgtt
     5941 tctcctatga agatcggtaa gcagatgcag ttcttcggag cccgtgcgaa tttggcgaaa
     6001 tgtttattat atgcgatcaa cggaggacgg gatgagcgca gcggcgtaca ggtagccccg
     6061 atgttcgagc cggttcgcgg cgagtatctg gaatacgatg aggtgatggc taagtatgag
     6121 caaatgatgc gctggttggc gaaagtgtat gtgaacgcct tgaagataat ccattatatg
     6181 catgataaat acgcatatga ggcattcgag atgtcgcttc acgatggaga tgtagagcgt
     6241 atccgtgcga caggtatcgc cggtctttct atcgttgccg attcgttggc tgctatccgt
     6301 gatacgaaag tacgtgtgat ccgtgacgag cgtggcttgg cggttgattt cgaacgtgag
     6361 ggagaatatg ttcctttcgg taataacgac gatcgtacgg atagtatcgc tgtagagatc
     6421 accgagaagt tcatggaata tttgcgtcag cacgagacct atcgccatgc gaaacctacg
     6481 cagtccatcc ttacgatcac ctctaatgtg gtatatggta agaagactgg tacgacaccg
     6541 gatggccgta tcggtggaac tcctttcgct ccgggcgcga accctatgaa cggtcgtgat
     6601 acgaaaggtg ctatcgctgc gctagcttcg gtagcgaagc ttccattcca gcatgcgcac
     6661 gacggtatct cttatacttt cgctgtttct ccggctacgt tgggaaagga gcgtgaagtg
     6721 cagatcaata atctggttag cttattggat ggctatttta ctccggatgg aggtcagcat
     6781 ctgaatgtta acgtatttga taaggatttg ttgatcgacg ctatggaaca tcctgagaaa
     6841 tatccgcaac ttacgatccg tgtatccgga tatgcggtaa acttcgtgaa actgactcgt
     6901 gaacaacagt tggatgttat ttcaagaacc attaaccatt cactgtaagt gataaaaggt
     6961 aagatacatt cattagagag tttcgggacc gtagatggtc ccggaattcg ctttgtcgtt
     7021 tttatgcagg gctgcccgtt gcgttgcctg tattgccata acccggatac ttggaacccg
     7081 aaagggaagg tgaaatatca gatgactccc ggcgagctat tgacggaagt cttacggtat
     7141 aagagtttta tcgcccgtgg gggggtgact gttaccggtg gggaaccttt attgcaacct
     7201 gagtttctga aagagttttt ccgtttgtgc caagagcaag gtcttcacac agctttggac
     7261 acatctggtt tcgtatgtac ctcaaaagct tgggaagtct tggattatgc ggacttagtg
     7321 ttattggaca tcaaaacctt aaacccggat ttacatccgt tactggcggg tgtcaagcag
     7381 gataatacgc ttctgttctt ggatgaattg gagagacgtg gcatagatac ttggattcgc
     7441 catgttattg tccccggata tacggataat gacgagtggc tggaggcgtt agctcggtat
     7501 gtcagttcat ataaagtggt tcgcaaagtg gaattattgc cttatcatac gatgggaacc
     7561 tataaatatg agcaattagg tctcgattat ccgttaaagg gggtggaacc cttatcaaaa
     7621 gaacgtttag ataatgcgaa agcgatattc tctcgctaca aaccagaaaa taacaaggcc
     7681 tgatctctcg atcaagcctt gcgattatgc aacagctaat cagggaaaac aatctaatcc
     7741 gattagcttt taaacgatag taataatttt ttgcctagac taaccttgac tatttaatat
     7801 gtgtttgttt tgttatatgc aacaaatatc tatttttgta aggagataaa aaatgatata
     7861 gatcagaaaa tgatgaatag tatgaagaca ccacaagaaa tagccgaaat gatatccaaa
     7921 cgtttttatc cattacccga tgcggatttg gattctctgg cctcgatcat agaatcaagt
     7981 aaggctgcga aaggagaatt attgttggat aacggacaaa tatctaaata tttatattat
     8041 gtggaatcgg gattattacg ccagttttac tataagaata aacgtgatat taccgagcat
     8101 ttctcctgtg agggaaatat cgttatttgt atagccagca cattccaaag agaaccgacg
     8161 cgtttattaa tcgaggcatt ggaaccgacg gtttatcacc ggatctcttt ttcggaattt
     8221 agcgatttat tgaaaacatc tttagctatt aatagattgt accagaaaat actggagtgg
     8281 gctttgatgc tttcgcaaga gaaagcggac tcttggcgtt ttgagtcggc aagaaaacgt
     8341 tatctgcgtt ttcaacagga atatccggaa gcagcgaaac gtgcttctgt caatcatatc
     8401 gcctcgtatt tattgatgac acccgaatct ttgagccggg tgcgggcggg agtgttgtag
     8461 tctctaccta cattcaggta ttattgaggt gaaaatagca atttgtggtg atttcacggt
     8521 tcaagtaatc catctatatt tgcgtcagtt taaaaaacgt agaagcaatg aaaatagaaa
     8581 agattacagg acgtgagatc ctagattcaa gaggtaaccc gacagtagag gttgatattt
     8641 tactagagtc cggcgttatg ggccgtgcgt ctgtgccttc cggtgcgtcc accggcgaga
     8701 acgaggcttt ggagttgcgt gatggcgata agaagcgtta tggtggtaaa ggcgtattga
     8761 aagcggttga gaatatcaat acgattatcg ctccggcatt gaaggggatg tctgccttgg
     8821 atcagatagg tatcgatcat gcgatgttgg ctttggacgg tacgaaaact aaatcgaaac
     8881 taggtgcgaa cgctatcctt ggcgtttctt tagctgtagc gaaagctgcc gcaaattatt
     8941 tggatattcc tttatataga tatattggtg gaacgaatac ctacgtgatg cctgttccga
     9001 tgatgaatat aatcaatggc ggttcgcata gcgacgctcc gatcgctttc caagagttta
     9061 tgattcgtcc ggtaggtgcc gcttctttca aggaaggctt acgtatgggc gctgaggtat
     9121 tccatgcgtt gaaaaaggta ttgcacgatc gtgggttaag taccgctgtt ggtgatgagg
     9181 gtggtttcgc cccgaatttg gaaggtacgg aagatgcctt gaactcaatt atcgctgcta
     9241 tcaaggcggc tggttatgaa ccgggcaagg atgtgatgat cggtatggat tgcgcttctt
     9301 ctgagtttta taaggatgga atctacgatt acacgaagtt tgaaggagaa aaaggagtga
     9361 aacgtacttc cgacgaacaa gtggattatc tggaaaagct gatcaacgaa tacccgatcg
     9421 attccattga ggatggtatg agtgagaatg attgggctgg ttggaagaaa ctgacagatc
     9481 gtattggtaa ccattgccaa ttagtcggag atgatttgtt cgtgacaaat gtagagttcc
     9541 tttcaagggg tattaaagaa ggttgcggta actcaatctt gatcaaggta aatcagatcg
     9601 gttccttgac ggagacactg aacgctatcg agatggctca ccgtcatgga tacacgaccg
     9661 ttacttcaca ccgttccggt gagacggaag acgctacgat cgccgatatc gctgtcgcta
     9721 ccaatagcgg acagatcaag acgggatcat taagtcgttc ggaccgtatg gctaaatata
     9781 accagctgct tcgtatcgag gaggaattgg gagaccgtgc cgtatacgga tacaaaagaa
     9841 tcaattaagt atataaagta aattataatc gctaattatg tagtaatcca aaacccaaga
     9901 tattgaaggg cttatccgtg aggataggcc ctttttattg attgataaag tgttatctat
     9961 aacctcataa aatatatcga ttagaaaaat tgttttaatg aagaaatatg ttatattttt
    10021 gtatcggaaa taaaaacaaa tagtattcat ttaaaaatag gaacaagtat ggaaccgatt
    10081 attaattctc aacttccgga gtttaaagta caagcttttc aaaatggtaa tttcaagact
    10141 gtaaccaacg aggacgtttt gggtaagtgg gctatctttt tcttctaccc ggccgatttt
    10201 acatttgttt gtccaacaga gttggtcgat atggctgaga agtatgagca gtttaaatca
    10261 atgggagtag aaatttactc tgtaagtaca gactctcatt ttgtacataa agcttggcat
    10321 gacgcttccg agactatccg taagatccaa tatccgatgt tggcggatcc cactggagca
    10381 ctgagtcgtg cgtttggtgt gatgattgag gaagagggta tggcataccg tggcactttc
    10441 ttggtaaatc cggaaggaaa gatcaaagtg gccgagattc atgataacaa tatcggtcgt
    10501 gacgcttccg agttacttcg taaagttgaa gccgctcagt ttgtcgcttc acatgatggt
    10561 gaggtttgtc ccgctaaatg gaagaaaggg gaggctacct tgaaacctag cattgacttg
    10621 gtagggaaaa tctaaataat taagagtata gatcgtgtta gaatcaacat taaaagaaca
    10681 attaaaaggt atattcgcag ggttaaatgc gaattatacc tttgatatat cgatctctcc
    10741 tgcgcatgaa agtagacaag agttgttgga tttattaggt gatgttgcct cttgttcgga
    10801 taaaatatct atgcgagtat ctgatgggga tggattggaa ttcattttat taaaggatgg
    10861 agcgaaaacg gggattaagt ttcgtggagt acctaatgga cacgagttta cttccttgct
    10921 gttggcgatc ttgaattcag atgggaaagg caagaatttt ccggacgaga gcatttgtaa
    10981 tcgtgttaaa gccttgaatg gcccgataca tctgacgacc tatgtctctt tgacttgtac
    11041 gaattgcccg gatgtggtac aggcattaaa cgctatgacg actttaaatc ctcagatcca
    11101 tcatgagatg gtagatgggg ctatcaatca ggcggaagtt gatgccttga agatacaagg
    11161 cgtcccctct gtctttgcgg atggaaaact gatccatgta ggacgtgggg aattcggtga
    11221 attgttatcg aagctggaag ctcagtatgg aatcaatgag agcctgacgg agaagacggt
    11281 aaaacgatat gacgtggttg tggtcggtgg gggtccggct ggtgcttctg ccgctattta
    11341 ttccgcacga aaggggctga gtgtcgctgt cgtggcggag cgtatcggcg ggcaggtgaa
    11401 ggagacggta ggaattgaga atctgatttc agttccggag acaacaggta cccagttggc
    11461 tgacaatctg cgcttgcata tgcggcaata tccgattgac ctgctggagc atcgtcgtat
    11521 agagaaggta acgatagaag gaaacgagaa ggttttatct acggctggag gtgagatatt
    11581 caaggctccg gcggttattg tcgctacggg cgctagctgg cgtaaattga atgtaccggg
    11641 tgaggcagag tatatagggc gtggagtggc tttttgtcct cattgcgacg gtccgtttta
    11701 taagggaaaa catgttgccg tggttggcgg tggaaattcc ggtatcgagg cggctattga
    11761 tttggcgggg atctgttcga aagtaaccgt tttggagttt atggatgagt taaaagcgga
    11821 tcaagtcttg caagagaaag cgaagagttt gccgaatgtc gagatctttg ttagttcaca
    11881 aacaaccgag gtggttggaa atggcgacaa ggtaaccggt atccgtacaa aggatcgtaa
    11941 gacaggggaa gagcgtgtta ttcatttaga cggtattttt gttcaaatcg gcttagccgc
    12001 taatagtggt gtctttaagg agattgtcga aacaaatcgt cccggtgaga tcgtgattga
    12061 cgcacattgc cggacgaatg tcccgggtat ttatgcagcg ggcgacgttt ccaccgtacc
    12121 ctttaagcaa atcattattt ctatgggaga aggcgccaaa gcggcccttt cggcctttga
    12181 agatcgggta cgtggtgtac tcggttgatg aaatacctac aaataggtaa tttttgaaca
    12241 gcgtatctct tttatcggtt atattactat atttgcgatc gagagaaaag agatggatag
    12301 attaagaaaa tatctgagga tattactccc tgcgctgttc atagcctatt tgggatgtat
    12361 tattgcgttt acccacgttc atattgtcaa cggggtaaca atcgtccatt ctcacccgta
    12421 tcataaaacg gacgatggtc gtccggacca tgaacatggc tacgccgagt ttcagttgct
    12481 tcatcagtta tctgtcttgc agataacagg tgcggctttc gtcgctattc tgctggcggc
    12541 tttttattcc tttatccgta acttatcttt cgctccggtc tatccggact atatcgttcc
    12601 cttccgggga agacgtacgc ttcgggctcc tcccatattc tgatattgtg agattaataa
    12661 cattgtatta cttatcagaa taaattaaaa tgaataaatt tttcatcttt atactatgcc
    12721 tgtgctgtgc cctaacggta gctcaggcca cgggagagga ccgtctaaac gactcagacg
    12781 caaatgtttt cggacatgtc ttggataaga aaacagggga acatcttccc tttatcaacg
    12841 tattgttaaa aggtaccacg atcggtacga ccaccgataa ctcgggacat tatttcctga
    12901 agaatctgcc ggaaggtaaa tttacgctgg aatataaagc gctcgggtat aagactgtct
    12961 ctaaagaagt gagcctaaag aaaggaaaaa ccttagagat taatgtagaa ctggaagaag
    13021 accagatcgc cttggatggc gtggtggtat ctgcgaatcg tgcggaaact tcccgccggt
    13081 tggctcccac attagtgaat gtattggatg cgaaggtttt tactacgacc aatgcggtga
    13141 atttggcaca gggactaaat ttccaaccgg gtgtacgggt ggagacgaat tgccagaatt
    13201 gcggtttcca gcaagtccgg atcaatggat tagacggacc ttatacccaa atactgattg
    13261 attcacgtcc catattcagt gctttatccg gcgtatatgg gcttgagcaa ataccggcga
    13321 atatgatcga gcgggtagag gtgatgcgag gagggggatc ggcactgttc ggctcgtccg
    13381 ctatcgccgg gacaattaat atcatcacga aggagccctt gagaaattcc ggggaattgt
    13441 cgcatacgtt aacctcgatt ggcgggacat ctgctttcga taataatacg accctaaatg
    13501 cctctttggt atcggaaaat gggaaagcgg gcttatatct ttttggccag aaccgtcatc
    13561 gttccggttt tgatcaggat ggagatggtt ttacggagtt gcctaaattg aagaatcaaa
    13621 cggttggttt ccgttcgtac ctgaaaacga gtacttatag taaattgaca ttcgagtatc
    13681 atcatatgaa tgaataccgc aggggaggaa atctgttgga tcgtccgcct catgaagcgg
    13741 atatcgccga acagttggag cattcgattg atggaggagg tctgaaattc gatcttttct
    13801 ccaaggatta caaacataaa tggagtgttt tcacttctgc ccagaataca gaccgggata
    13861 gttattacgg gacgaaccaa gatccgaacg cttacggcaa gactacggac ctgacggtta
    13921 tggccggtac gcaatatgct tatagttttg ataaattctt gtttatgcca tcggatttga
    13981 ctgccggttt ggagtatagt ttcgatcatt tgaaagacga gatgatcggg tataatcgct
    14041 ttacgaatca gaaggtgcat atcgagagtg cgtttttgca gaatgagtgg aaaaataagc
    14101 gatggagctt cttgattggc ggtcgtttgg ataaacataa tatgatggat catgtaatat
    14161 tcagccctcg tgcgaatatc cgttttaacc cgacggaaga tatcaatatc cgggctagtt
    14221 attccagtgg tttccgtgcc ccgcaagcgt tcgatgagga tatgcatatc tcggcggtcg
    14281 gcggagaggt cgctatgatc cagcgtgcga aagatttatc cgaggagaaa tcgcagagct
    14341 tgagtgcttc ggtcgatttt taccatcgtt ttaagaatgg tatccagttg aacttcttgg
    14401 tggaaggttt ttactccagc ttaagtgatg tgtttgtctt ggaagatatt gggaaagatg
    14461 agcaaggcaa tctgattaag gaacgtcgta acggttccgg ggcgaaagtg atgggattaa
    14521 ccttggaagg aaagtcggtg ttaacttcat ggctatcttt gcaagcgggc gctactttcc
    14581 agcgaagccg ttataaagag gccgagaaat ggagcgatga cgagaatgtg ccagccgaga
    14641 caaagatgtt ccgtacgccg gatatctatg gttattttac ggctaccctt acgcctttca
    14701 aacgtttcac ggcttccctg tcgggaacct atacgggaag tatgttggtg cagcatttgg
    14761 cgggatatat acctttggat aaggcggtgg agactccgga tttctttgat atgaatatca
    14821 agcttgcgta tgagttcccg ctttacaaag agctgaaact agaagtaaat ggaggcgtgc
    14881 agaatctgtt taacgcttac caatccgact ttgaccaagg taagaaccgg gattcctcct
    14941 atatctatgg cccggctagt ccgagaagtt attttgccgg tgtaaagatg agtttttaat
    15001 catgtaatgc cctttgaaaa aacatgtacg tgtttcgtga aaaacatgta cgtgtttccg
    15061 aaaaaagacg tacgtgtttt tttgaaggca aaataaacaa aaagacagtg ttcccaagca
    15121 tatgatcgct ctacggaaac actgtctttt ttatgggata aatcgggatg ttttatttaa
    15181 cgaacggagc ggcttgcaaa taggcggcgc tcttctctac gccctcgaac tgggtacggc
    15241 cttttttgtc accttccagt tccacgtagt agccgaggat accgatctcg tacgcttttt
    15301 tgaatatatt cgggaaattc atcataccgg aatcaccgat gatccaacga tccttgatgt
    15361 gcaataactt aaaacgattc ggataattct ccatccattc cacgggatct tgctgcccca
    15421 taacggccca atatacatcc aactcgaaca taaccttatc cggatcggta ttttttagga
    15481 ataactcctc gatataagta cctttaggag gtgcccacgg attcgggttc tgttccggtt
    15541 tctcgccggc tttcaatacc cgtttgaact cattgctatg attatggtaa ccccatagga
    15601 ttccggcttt cttcgtgatc tctccggcac ggttgaagat ctccgatact actttggcgt
    15661 catcctcgtt ttcgatacgg ggtaaactcg gttgtaccat acaactaaca cctagctcgg
    15721 catggatatc ggttgccttt ttccagaact cgtcgaattt gggcatattc tctttcgtgt
    15781 actcacgaag agaaggggtc aggtgtgagc tactgattct caaaccggca tcatccacca
    15841 ttttcttata atccttggag gcgatgaatg tcgtattttt aggattataa tcaccgaatt
    15901 taccagtgtc ttccctatat ccgaaaatct ccagatcggt atatcccgct tttgccaatc
    15961 ggttcaatcc gttaggcata tcttgcagta actcctgtcc gagcgaatag gtttgcaatc
    16021 ccatcttttt cccggcggtt gccgaggata tcgcatccgt ggcgggtatg gatctggtgg
    16081 gatttgaagc cattactttt tggctggcta tgccccctaa agtaagtaat gaaatgtttc
    16141 tcaaaaatgt tcttctgtct gtcatggtga taaagaatta aaattaaaca tctgtttctc
    16201 gcaaatatag ttaacctttt tgaagtttat taagaaaatg tctctcaaaa acttgcgatt
    16261 gggtttaaat agatttaaaa tttgacataa ctcaatttta cgaacttact ccatacatcc
    16321 aattacctga ataaggggat tgtttggtat acctccgtgg atttttaatg tgattttacc
    16381 cattcttagg tattgtggga cggtagtctc tgatcgtaac tttgcagcgt tttaaataac
    16441 ataattgatt aaatgatgat gaagaaaatc agagggcttt tcctctcctt tttactgttg
    16501 cttatttcca tctcggcttt ttctcaacat aaaacaatga tatcgggtaa agtcctgtcc
    16561 acggaaaaaa caaccgtgga tttcgctacc gtttatctaa aaggtacgaa ttacggcggg
    16621 actacgaatg aggaaggtat ctatcatctt caagctcccg cgggagaata tacattagta
    16681 gtatcggcta tcggatataa gacggtagag aaacccgtga aactgatgcg tggggaacgg
    16741 acgaagatga atgtggtaat cagccctcaa gctacggagt tggatgaggt ggttgtcgtt
    16801 tctaatggcg tgacccggct caagcgttct gcgttcaatg ccgtggccct cgatacgaaa
    16861 gccttgcaaa attcaaccca gaacttgagt gaagccttgg ctcaagcgcc cggaatgaag
    16921 atccgggagt ctggcggtgt cggctcggat atgcaactga tgatggatgg atttaccggc
    16981 aagcatatca agatctttat cgatggggtt ccgcaagaag gtgtcggcag ttctttcgga
    17041 ctgaataaca ttccggtgaa ttatgccgag cgtatagagg tctataaggg tgtggtaccg
    17101 gtgggtttcg gaacagacgc tatcggaggt gttatcaata tcatcaccaa gaagaaccgg
    17161 aacaaatggt ttttggatgc ttcttattca tacgggtctt tcaatacgca taaatcttat
    17221 gtgaacttcg gacagacttt ccggagcgga ctcacgtatg agatcaacgt tttccagaat
    17281 tattcggata ataattacta tgtggatact ccggtgaagg actttacgac cggagcgatc
    17341 aataagaaaa agatcgagca tgtgaagcgt tttcatgata cgtatcataa cgaggccgtt
    17401 atcgggaaaa tcggtttcgt ggataagaaa tgggcggatc gtttgatgtt cgggtttacc
    17461 tattcacata tgtataaaga tatacagacg ggcgtacgcc aagaagtggt gtttggcggc
    17521 aaatatcgga agggatactc gatcatgccg tcgttggact atcgcaagcg tgatttcttc
    17581 gttaggggct tggatgtggt attgacggcg aattataata agaacatgac gaacaatgta
    17641 gatacctctt cctatgaata taattggcgt ggcgagatgc gtc
//
