LOCUS       gnlProkkaMGJJDJCH_5     9500 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MGJJDJCH_5.
ACCESSION   gnlProkkaMGJJDJCH_5
VERSION     gnlProkkaMGJJDJCH_5
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-30 21:28:45
            Original ID  :: gnl|Prokka|MGJJDJCH_5
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9500
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9500
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[227:4500]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      228..4500
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..9500
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9500
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(3..215)
                     /locus_tag="ctg5_1"
                     /transl_table=11
                     /translation="MLKKRLDYSQLKVIQLNILKDVDAFCRENNITYYLTYGTLLGAVR
                     HQGYIPWDDDIDIAMPRKDYEKFLSI"
     CDS             complement(228..1337)
                     /NRPS_PKS="Domain: Aminotran_5 (30-293). E-value: 2.7e-33.
                     Score: 107.2. Matches aSDomain:
                     nrpspksdomains_ctg5_2_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 79.2; E-value:
                     4.8e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_2"
                     /sec_met_domain="Aminotran_5 (E-value: 4e-31, bitscore:
                     98.1, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIERKILLNPGPATTTDTVKLAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGDLSKHTAVLFCGSGTINIDICLNSLLPADKKVLVVNNGAYSTRAVEVCEYY
                     GLPHIDLKFSVYELPDLSVIEKTLSDNPDIALVYTTHHETGTGILNPIREIGKIAHSHD
                     AVFVVDTTSSLGMIPFDIGKDNVDFCMASAQKGLQAMTGLSFIVGDESLIRASRDYPKR
                     SYYCNLYLQYDYFEKTGEMHFTPPVQTVYAARQALDEYFAVGEEAKFARHKRVFEAIHK
                     GLQELGLQYAIKREWQSGLVVSVLYPDDPLWDFDKVHDYCYERGFTIYPGKISTTNTFR
                     LCALGEIDVEDIERFFEVMKSVNTVLVNK"
     aSDomain        complement(459..1247)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg5_2_Aminotran_5.1"
                     /evalue="2.70E-33"
                     /label="ctg5_2_Aminotran_5.1"
                     /locus_tag="ctg5_2"
                     /protein_end="293"
                     /protein_start="30"
                     /score="107.2"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGDLSKHTAVLFCGSGTINIDICL
                     NSLLPADKKVLVVNNGAYSTRAVEVCEYYGLPHIDLKFSVYELPDLSVIEKTLSDNPDI
                     ALVYTTHHETGTGILNPIREIGKIAHSHDAVFVVDTTSSLGMIPFDIGKDNVDFCMASA
                     QKGLQAMTGLSFIVGDESLIRASRDYPKRSYYCNLYLQYDYFEKTGEMHFTPPVQTVYA
                     ARQALDEYFAVGEEAKFARHKRVFEAIHKGLQELGLQYAIK"
     CDS             complement(1334..2470)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 70.6;
                     E-value: 1.9e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_3"
                     /sec_met_domain="TPP_enzyme_N (E-value: 2.1e-22, bitscore:
                     69.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 7e-21, bitscore:
                     64.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSVEKIYDTFLHHGVDFFTGVPDSLLKNICAYITDHAPRGKHII
                     AANEGSAVGIACGYYMASGNVPLVYMQNSGLGNTVNPLLSLADEKVYSLPLLLLVGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMKIPFIILDTDEDEALAQIHDAVVSAKSRSIPHAIV
                     IRKDTFGKYKLRQEALNDYPLSREEALMQVVDHLGDNDIVVSTTGKLSRELFEYRESKG
                     QGHARDFLTVGSMGHSSSIALGIALEKPDRRVYCLDGDGAFIMHMGAVSNIGDLSPKNY
                     RHVLFNNGAHESVGGQPTLGFRLDIASIAKGCGYAHVLTASDKEGLSCALEKLSGLSGP
                     VLLEIKVRIDSRDDLGRPTTTPVENKEHFMAFLKDTHS"
     CDS             complement(2482..3312)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208.6;
                     E-value: 1.9e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_4"
                     /sec_met_domain="phosphonates (E-value: 4.2e-115, bitscore:
                     373.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 3.3e-64, bitscore:
                     206.5, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVRILEAHDGLCGLIIENLEVQKGDKREVFDGMWSSSLTDSTSKG
                     KPDIEAVDLTTRLQDLNNILECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAVIIED
                     KVGLKKNSLFGTDAIQTQDSIEGFCDKIRAGKNAQVTGDFMIIARIESLIAGKPMSDAL
                     ERAYAYVQAGADGIMIHSKDKSGEDIREFCRTFRKEYAHVPIVVVPTTYDHVHESELHE
                     WGANVVIYANHLLRAAYPAMMNVARTILENERAEEVRPLCMPIKEILELIPGTK"
     CDS             complement(3327..3782)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_5"
                     /sec_met_domain="CTP_transf_like (E-value: 3.1e-14,
                     bitscore: 43.3, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKIYVGMTADIMHPGLIHIIHEATKYGDVIVGLLTDKAIAEHK
                     RLPYLTYDQRKEVVENIKGVCEVVPQEDWSYVPNLEKLKPDYIIHGDDWKTGPLREVRE
                     QVFEVMNAQGGKVIEIPYTRGINSSSLDKDIKRSGLPLTYVLSPSAA"
     CDS             complement(3802..4500)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_6"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.5e-14, bitscore:
                     44.5, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAGLGTRFGHYTELVPKGFVEVGGKPMIIRSIETLLSCGIERII
                     LGTGYKKEAYEALQADFPQIETCFSPRYADTNSMYTLYNTRDVIGDDSFLLLESDLVFE
                     RKAILSLLDDEFPDVMLVSSLTKFQDQYYVEYDCNHILTSCSVDKDALEAKGELVGIHK
                     LSNTFYRRMCADYATILESQPKLGYEYELLRMSRSVSPVRVLRVEGLKWYEIDDEADLS
                     YAEEHIIRYC"
     CDS             complement(4514..5569)
                     /locus_tag="ctg5_7"
                     /transl_table=11
                     /translation="MKAGHRIYYIIGLLTFSEVALLGFALLPVPLKVCSIFLSGLPLGM
                     IWGVIFSYIEGRRISEILNVGLSVALIVSSGLVKTLGQFVMDNLHVSEYWMPFTTGLLV
                     YPVMLLCSWLLNQIPAPNEQDIIQRTKRAPMDGKDRRKFLRQFFWGICMLVVFYGALTV
                     FRELRDSFAADIWKELHIEGAMIFTQTEVPIAVFVLVLMFLIVFVRNNRLALNIIYCIA
                     VTGGSLMVFSTLLYVYGFLSPIWWMILSGLGLYMGYIPFTYLIERLIASLRVVSTAVFI
                     IYLADSFGYLGTTGVFMVKNFVSADISWTVMLMRTALFSGFVSVLSIFAIYCYFKQQLN
                     SLILIPSEIHD"
     CDS             complement(5566..5796)
                     /locus_tag="ctg5_8"
                     /transl_table=11
                     /translation="MIRSFLSRSPLYVLALYASVLIFLVYTCAYAYRKPFTAAIYEGEI
                     LWGFDVKILYVLSEIIATPFPSSSVFVFCLR"
     CDS             complement(5793..6278)
                     /locus_tag="ctg5_9"
                     /transl_table=11
                     /translation="MNTLTSQIEQLQSLAHELLYLGVDGAPIYTDHFRQLNKEVLEQSD
                     ALYPQRGATPEEEANICLALLMGYNATIYNQGDKEEKKQVVLNRCWDVLDQLPATLLKC
                     QLLTYCYGEVFEEELAKEAHTIIESWSNRELLKAEKEIAESLNNLEANPYPYSELHE"
     CDS             complement(6282..6806)
                     /locus_tag="ctg5_10"
                     /transl_table=11
                     /translation="MSEQQKYWFAARTRDKQEFAIRDSLEKLKTELDLNYYLPTQFVIR
                     QLKYRRKRVEVPVIKNLIFIQATKQDACDISNKYNIQLFYMKDLLTRAMLIVPDKQMQD
                     FIFVMDLDPNGVSFDNDHLSVGSRVQVVKGDFCGVEGELASEANKTYVVIRIAGVLSAS
                     VKVPKSYLRVI"
     CDS             7327..7665
                     /locus_tag="ctg5_11"
                     /transl_table=11
                     /translation="MNDNLVTIEVNGKVIFAGKADLQFSLNQKVREPLRITKGKGKLME
                     ALTESFIKGGINSMENRPIEELQETIKEYLTFEYQRKGIATEPNKRSFLSELKKYARAF
                     RKKRDESE"
     CDS             7806..8153
                     /locus_tag="ctg5_12"
                     /transl_table=11
                     /translation="MKKNRKAVSKNEMMKGKWKRQIMLEKDYTEQCSEWMAERLEALIE
                     YMQYGHAAVAYMKQDGTFKLVKGTLVGYEKDFGKQYDPMEIKNTVVYRDVEQQRWMTFK
                     IENFMEWRAIV"
     CDS             8203..9006
                     /locus_tag="ctg5_13"
                     /transl_table=11
                     /translation="MATTYDGINYFPIAVNFMEENAMEVIEAKYGMKGLAIVLKLLCKI
                     YKEGYYIPWGEEQCLIFANKTGKEADAEEVQGIIEIMIEKGMIDRGSYAEHKVLTSKAI
                     QKVWIEATKRRKRNWTAMPYLLIKPKETCNEEKTVCTQNVEQDAGSDAKNACNTEQSKV
                     KQSREFPPSAPPRGKEEEVNATPVSMPGYAFNTMTHNYVGLMGNLERFGITDEKEIEAI
                     LRLSDYGRKGTPVWKLICSTNWSNIGAKGKYMIAALNRAKKRSGT"
ORIGIN
        1 ataattgata aaaacttttc ataatctttc ctcggcatag caatatcaat atcgtcatcc
       61 caaggaatat atccttgatg tcttacagcc cccaacaaag tcccataagt taaataataa
      121 gttatattat tttcacgaca aaaagcatct acatctttta atatattcaa ctgtataacc
      181 tttaattggg aatagtccaa cctttttttc aacatgaatg agctaaatta tttattaact
      241 aataccgtat ttacgctttt catcacctca aagaacctct caatatcctc cacatcaatc
      301 tctcccaacg cacaaagccg gaatgtattc gttgtggaaa tcttacccgg gtagatcgta
      361 aagccacgtt catagcagta atcatgaacc ttatcaaaat cccagagggg atcatcagga
      421 tacaatacag aaacaacaag acccgactgc cattcacgtt tgatcgcata ctgaagacca
      481 agctcttgca aacctttatg gatggcttca aagaccctct tgtgacgggc gaatttagcc
      541 tcttcaccta ctgcaaaata ttcatcaaga gcctgacggg cagcgtaaac ggtttgaaca
      601 ggaggagtaa aatgcatctc acccgtcttc tcaaagtaat cgtattgtaa atagaggtta
      661 caatagtagg aacgtttcgg ataatccctt gaagcacgta tcagggattc atcacctacg
      721 ataaaggaaa gacccgtcat ggcttgaagg cctttctgag ccgaagccat acaaaagtca
      781 acattatcct tcccgatatc aaaaggaatc atacccaggg aagaagtggt gtcgacaaca
      841 aaaacggcat cgtgcgaatg ggctattttt ccgatctcac ggatggggtt caagataccc
      901 gtacccgttt catggtgcgt ggtatagacc aaagcgatgt ccggattgtc ggaaagcgtc
      961 ttttcgatta ccgacaggtc gggaagttcg taaacggaaa acttcaaatc gatatgggga
     1021 agaccgtaat attcgcagac ttccaccgca cgggtgctgt aggcaccgtt attgacaacc
     1081 agaactttct tatccgcagg aagaagagag ttcaggcaga tatcgatatt gatcgtaccc
     1141 gagccgcaaa acaggacggc cgtatgtttg gagaggtctc catgcgcaac gcggaccagg
     1201 tcgtcacgta actgtttcat catacccgca aactctttct cacgcggaca gatatcggga
     1261 acaacctgcg ccagcttcac cgtatccgtc gtggtggcgg gacccggatt caaaaggatc
     1321 tttctttcga tattcatgaa tgcgtatctt ttaaaaatgc cataaaatgc tctttattct
     1381 ctaccggagt agtcgtaggg cgacccagat catcacgtga atcgatccgg accttaattt
     1441 caagaagaac cggaccggac aggccggaca gcttctcaag cgcacacgaa agcccttcct
     1501 tgtcggaggc agtcagtaca tgcgcataac cgcaaccttt cgctatcgag gcgatatcca
     1561 gacggaaacc gagcgtgggt tgaccgccga cagattcatg ggcaccgttg ttgaaaagga
     1621 cgtgcctgta attcttggga gaaagatcgc cgatattgct gacagcaccc atgtgcatga
     1681 taaaggcacc gtcaccgtca agacagtaga cacggcggtc aggcttctca agggcaatcc
     1741 ccagggcaat ggaagaactg tgccccatgg aacccacagt taggaaatcc cttgcgtgcc
     1801 cctgcccttt cgattcgcgg tactcgaaaa gctcacggga gagcttgccc gtggtggaaa
     1861 ccacaatgtc attgtccccg aggtggtcga caacctgcat tagcgcctcc tcgcgggaca
     1921 gaggatagtc attcaaggct tcctgacgca atttatattt tccaaacgta tctttacgga
     1981 tgacaatcgc atggggaatc gaccggctct tcgccgagac aaccgcgtca tggatctgcg
     2041 ccagggcctc gtcttcatcc gtatccagaa ttataaaagg aattttcatg gctttcagaa
     2101 gatcaagggt aacctcgccc tgcttcttat gctggggttc gtctttcgtg ccgggctcac
     2161 cgcgccagcc gaccagcaaa agaagaggaa ggctgtacac tttctcgtcc gcaagggaca
     2221 agaggggatt caccgtattt cccagaccgg agttctgcat ataaaccaaa ggaacgttgc
     2281 cagaagccat ataataaccg caggcaatgc ccaccgcgga accttcattg gcggcgatga
     2341 tatgcttacc acgcggagca tgatccgtga tataggcgca aatattcttc aaaagggaat
     2401 cgggaacacc cgtaaagaag tcaacaccgt gatgaaggaa cgtatcgtat atcttttcta
     2461 cacttaccat aaccgtctga tttatttagt gcccggaatc aattccagaa tttccttgat
     2521 aggcatacaa agcggacgga cctcctcggc gcgctcgttt tcaaggatgg tcctggccac
     2581 gttcatcatg gccgggtaag cggcacggag aaggtggttg gcgtaaatga ctacgttggc
     2641 accccattcg tgaagttcgg attcgtgcac atggtcataa gtcgtcggaa caacgacaat
     2701 gggaacatgg gcgtattctt tgcggaaagt ccggcagaac tcacggatat cctcacccga
     2761 cttatccttg ctgtggatca tgatgccgtc cgcacccgcc tgtacatagg cataagcacg
     2821 ttcgagggcg tcactcatgg gtttgccggc aataaggctt tcgatacgcg caatgatcat
     2881 aaagtcaccg gtgacctggg cattcttccc tgctctgatc ttatcgcaga aaccctcgat
     2941 actatcctga gtctggatag cgtcagtacc aaaaagggaa ttcttcttca gaccaacttt
     3001 atcttcaatg attaccgcag aaatgccgtg acgttccaaa gtgcgcacag taaagacaaa
     3061 gtgttcgatc ttgccacccg tgtctccatc aaaaataata ggcttggtgg tgcattcaag
     3121 gatattgttc aggtcctgta aacgggtggt aaggtcgacc gcttcaatat ccggtttacc
     3181 cttactcgtg gagtcggtca ggctgctgga ccacatgccg tcaaagacct cgcgcttatc
     3241 acccttctgg acttcaagat tctcaataat cagaccgcaa agaccgtcgt gagcctccag
     3301 gatacggacc acaggcttgg cctggatcag gcggcggagg gacttaagac gtacgtcagg
     3361 ggtagtcccg atcgcttgat atccttgtcg agcgaggagg agttgatgcc ccgggtataa
     3421 gggatctcga ttaccttgcc cccctgggcg ttcatcacct caaaaacctg ttcgcgcacc
     3481 tcgcgcaacg ggcccgtttt ccagtcgtca ccgtggatga tatagtcagg cttgagtttt
     3541 tccagattcg gaacatagct ccaatcctcc tggggaacaa cttcgcaaac ccctttgata
     3601 ttctcaacaa cctccttacg ctgatcatag gtaaggtaag ggaggcgttt gtgttcggcg
     3661 atggccttgt ccgtcagcag accgacgatg acatcaccgt atttagtagc ttcatgaata
     3721 atatggatca gccccggatg catgatatcc gcggtcatac cgacatagat tttcttgttc
     3781 atatatggaa aagatttgtt tttaacaata gcggatgatg tgctcctcag catacgaaag
     3841 gtcggcttca tcatcgattt cataccattt aagcccctcc accctgagca cacggacagg
     3901 ggaaacggaa cgggacatgc ggagcagttc gtattcgtaa cccagtttag gctgggactc
     3961 caggatggtc gcataatcgg cgcacatccg gcggtagaaa gtattggaaa gtttgtggat
     4021 gccgaccagc tcgccttttg cctcaagggc gtccttgtct accgaacagg aagtaaggat
     4081 gtgattgcag tcatattcca cataatactg atcctggaac ttggtcagag aggagacaag
     4141 catcacatcc gggaattcgt catccagcag cgagaggatg gccttgcgtt caaaaacaag
     4201 gtccgattca agcagcagga aactgtcatc gcctatcacg tcacgcgtat tgtacagagt
     4261 gtacatactg ttagtatcgg catagcgggg actgaaacag gtctctatct gggggaaatc
     4321 cgcctgaagg gcttcataag cctctttttt ataacccgta ccgaggatga tacgttcgat
     4381 accgcaggaa agaagggttt cgatagagcg gataatcata ggttttccac caacctccac
     4441 aaaacctttg ggcacaagct cggtataatg cccgaagcgg gtaccaagac cggcagccat
     4501 gatcattgct gttttaatca tgaatttcag agggaattaa tataagtgaa ttcaattgtt
     4561 gcttgaaata acagtaaatc gcaaaaatcg acaggacaga aacaaatcct gaaaaaaggg
     4621 cagtacgcat cagcatgaca gtccaggaaa tgtcagcaga aacgaagttc ttgaccataa
     4681 acacacccgt agtgcccaga tagccgaaag aatcggccaa ataaataata aaaacagctg
     4741 tactaaccac cctaagggaa gcaatcagac gttctatcag gtaagtgaaa ggaatatacc
     4801 ccatatacag accaagaccg gaaagaatca tccaccaaat aggagaaaga aaaccgtaca
     4861 cataaagcaa tgtggaaaaa accattaagg aaccgcctgt gacggcgatg caataaatga
     4921 tattaagagc caaacggtta ttacggacaa acacaatcag gaacatcagt acaaggacaa
     4981 aaacggcaat gggaacctct gtctgagtaa agatcattgc accctcaata tggagctcct
     5041 tccaaatatc ggcagcgaaa gagtcacgaa gctcacggaa cacggtcagg gcaccgtaaa
     5101 aaacaaccag catgcagatt ccccaaaaga attgcctcaa aaacttacgc ctgtctttac
     5161 catccatcgg agcacgtttg gtacgctgta tgatatcttg ctcattggga gccggaatct
     5221 gattgagaag ccagctgcaa agcaacataa cagggtatac caacaaaccg gtggtaaaag
     5281 gcatccaata ttccgacaca tgcaaattat ccatcacgaa ttgtcccaag gttttcacca
     5341 aaccggaaga gactatcaaa gcaacgctca gcccgacatt caatatttca ctgatacgac
     5401 gcccttcgat atagctaaaa atgacacccc agatcatacc caggggaaga ccgctcagaa
     5461 aaatagaaca caccttcaaa ggaaccggaa gaagtgcaaa acccaacaaa gcaacttcgg
     5521 aaaaagtaag cagccctatt atataataga tgcggtgacc cgctttcatc gaaggcaaaa
     5581 tacgaacacc gatgaacttg gaaagggcgt agcgataatc tcagaaagga catacaggat
     5641 tttgacatcg aatccccaaa gaatctcacc ttcataaatg gctgcagtaa atggcttacg
     5701 gtaggcatag gcacaagtat aaaccagaaa aatcaaaacg ctggcataga gagccaaaac
     5761 gtaaagggga gaacgggaaa gaaaggaacg aatcattcgt gtagttcgct gtacggatat
     5821 ggattagctt ccaaattatt caaactttca gctatttctt tttcagcttt taaaagttct
     5881 cgattgctcc aactttctat gatagtatgc gcctctttcg ccaactcctc ttcaaacacc
     5941 tcaccataac aataagtcaa caactggcat ttcaataaag tagcaggaag ttggtcaagc
     6001 acgtcccaac aacgattgag aacaacttgc tttttctcct ccttgtcacc ctgattatag
     6061 atggttgcat tgtaacccat caataatgcc agacagatgt ttgcttcctc ttcgggagta
     6121 gcaccacgct gaggatacaa cgcatcggat tgttctaaaa cttctttgtt caactgacgg
     6181 aaatgatcgg tataaatagg agcaccatcc acacctaaat agagtaactc gtgcgcgaga
     6241 ctctgtaatt gttcaatttg agaagtgagt gtattcataa cttaaatgac acgtaaataa
     6301 cttttaggaa ctttgacgct ggcgctcaat acaccggcaa tacgaataac aacataagtt
     6361 ttgttggcct cgctggcaag ttcgccctcg acaccacaga aatcaccttt aactacctga
     6421 accctgctac cgacagataa atggtcatta tcgaaactga cgccattcgg atctaaatcc
     6481 atgacaaata tgaagtcctg catctgttta tcaggaacta tcagcatagc cctggtaagc
     6541 aggtctttca tataaaaaag ctggatattg tatttattag aaatatcaca agcatcttgc
     6601 ttggtagctt ggatgaagat aagattctta ataacaggga cttccacccg ttttcgacga
     6661 tatttcaact gccggatgac aaactgagtg ggaagatagt aattgagatc aagttcagtc
     6721 ttcaattttt caagagagtc acgaatagca aactcttgtt tatctcgtgt acgggcggca
     6781 aaccaatact tctgttgttc agacatttac gatttatact tggggaaatt ttcctttgtt
     6841 tcgggtgcgc ttcgcggttt gaacgagaca tcttttctct ttcaaaccgt caaattttac
     6901 gaaacatttt tagaagttga gaacgaacga atgtgtttca aaaaacgttc gtttgattta
     6961 acaaaggtaa ggagtctgtt ttatgtacaa aatatttagt ggataaaatt ttatcaaaga
     7021 ttttatattg ttgattttca aacacatata gagcaaaaaa agttctctgc tcagcaactt
     7081 tacaatattc attttttcat cgaaaaaaac tcaaaaaatg ctgtttcaaa agacgaacgt
     7141 tttttgaaac aacacctata tcttaagata aataactaat aacaagatcc ttacagttca
     7201 agattctccc tttaagctaa aaaaactccg gtattctttt atatttatat tttttattac
     7261 aaactttgtc ctttcataaa ttcatttaat aactaacatt atggaagaaa aaaagtagtt
     7321 atctcattga atgataactt agtaaccatc gaagtaaatg gaaaagtaat ctttgcgggt
     7381 aaagccgact tgcaattcag cctcaatcaa aaggttagag aaccactacg catcacaaaa
     7441 ggcaaaggaa agctaatgga ggcacttacc gaaagcttta tcaaaggcgg aatcaacagc
     7501 atggaaaaca gacccattga agaactacaa gaaacaataa aagaatatct cacctttgaa
     7561 tatcagcgca aaggcattgc tacagagccc aataaacgtt cttttctatc agagctgaaa
     7621 aaatatgcca gagcattccg gaaaaagcga gatgaaagcg aataaccgat tgttaaaatc
     7681 ctgtaaaagc ccctttctaa agtactttta caggattagt ctattcaaaa cttattaccg
     7741 tactttgcca tgggtaaaaa taaaagcccg acaataactc attaataaac ttaaaaaaat
     7801 caattatgaa aaagaacagg aaagcagtat cgaaaaacga aatgatgaaa ggaaaatgga
     7861 aaagacaaat catgctcgaa aaggactaca cagaacagtg ctccgaatgg atggcagaac
     7921 gactggaagc cctcatagaa tatatgcaat atggacatgc agccgtagct tatatgaaac
     7981 aggacggaac attcaaactg gtgaaaggaa cattggtggg atacgaaaaa gatttcggaa
     8041 agcagtatga tccgatggaa ataaaaaaca cagtggtcta ccgggatgtg gaacaacaaa
     8101 ggtggatgac cttcaaaata gagaatttca tggaatggag agcgatcgta taggagaatc
     8161 tttcagtgac caattaatca gcaacataac aacttaacaa ttatggcaac aacatacgat
     8221 ggaataaatt actttccgat agctgtaaat tttatggaag agaacgcaat ggaggtaata
     8281 gaagcaaaat atggcatgaa aggactcgcg attgtactga aactcctatg caagatatat
     8341 aaagaaggat attatattcc gtggggtgag gaacaatgcc ttattttcgc caacaagacg
     8401 ggaaaagagg cagacgcaga agaggtgcag gggattatcg agataatgat cgagaaagga
     8461 atgatagaca ggggaagcta tgcggaacat aaagtactga cctctaaagc aatacaaaaa
     8521 gtatggatag aggcaaccaa gcgaagaaag aggaactgga cagccatgcc ttatctactg
     8581 ataaaaccga aagagacatg taatgaagaa aagactgtct gcacgcaaaa tgtagagcag
     8641 gatgcaggct ctgatgcaaa aaatgcatgc aataccgaac aaagtaaagt aaagcaaagt
     8701 agagaatttc ccccctcagc tcccccaagg gggaaggaag aggaagtcaa tgctacgccg
     8761 gtcagtatgc ccggatacgc atttaataca atgacacaca actacgtggg attaatggga
     8821 aacctggaac gattcggaat aacagacgaa aaagagatcg aagcaatcct gcgactgtcg
     8881 gattacggga gaaaaggaac ccctgtatgg aaactgattt gcagcacgaa ctggagcaac
     8941 atcggagcaa aaggaaaata catgatcgca gcgttgaacc gggcaaagaa aagaagcgga
     9001 acctaaaaag aacttttctg acaaacagta catttttata ttctggaaaa tgctgtttgc
     9061 ttgcagtcaa ttaaagaacg cagctgtttt cctccggaaa cgagcactga ttctcaaggg
     9121 gttgaaaagc gattcaaaaa gcactaatac gaagttaaaa tcgtgacttc aggaagttaa
     9181 cttcccgaag atacgatttt aacttcgtaa aattatgata ttaacttcgt aaacaacaag
     9241 atgttaactt cgtaaacggc atcatccgga catcaaagca atcaaaaaag attgtcagac
     9301 tatagtattt caggcagttg ccagacttgt atgtgacgaa tcccttcttt ggagggcaat
     9361 gtggtatcgt ccatagaaac gacccacttt tcataattgt cttgtatcat ctccagcgtg
     9421 ttgtacattt gctccacttg aaaatcatca ttgagcagag gtgcacattg caaatacaca
     9481 atgcggtctt tcttcctgcc
//
