LOCUS       c00189_gnlPro..        13977 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MGJJDJCH_231.
ACCESSION   c00189_gnlPro..
VERSION     c00189_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 23:55:41
            Original ID  :: gnl|Prokka|MGJJDJCH_231
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 5623
            Orig. end    :: 19600
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13977
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[15623:18581]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12958
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13977
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13977
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             239..481
                     /locus_tag="ctg189_7"
                     /transl_table=11
                     /translation="MYIVTENFESYAPTGGGDYVDRYGNKMRALAGMARWTPTIDGKQV
                     RKGGVGTYHMEYDYPGDIEYKYLREAIRIMNPAVK"
     CDS             499..1332
                     /locus_tag="ctg189_8"
                     /transl_table=11
                     /translation="MKRITIKQYLLACFVLPMILAGCNDADYQVIDNAIYLNEASENGS
                     AKVTVDPENVTTTTLTVRVGQPVTENVTAVLTVDPSILKEYNEANETSYEVLPEQYFTY
                     DKEIKIAAGDVSAIPSEFRVKPYSNENGELYAIPVSLTEIQGPVSTIGLSSKFIILLDK
                     PLIQSVPFMNTTNAVKPAKDELWGVTTNEWSLEAWVQMDGFDINNQAIFNSGSSDHEVY
                     IRFGDAMIPYNSLQVKTLGSQVNTVTLFEKNKWYHLASFIILPGYCRFISTECST"
     CDS             1299..1634
                     /locus_tag="ctg189_9"
                     /transl_table=11
                     /translation="LSIYINGVLDVTLQTKGGPVRFDKMNMVSSGSYFRNNCQMAQVRL
                     WKSAISQTQIQSNMYFAVKPADPNLIGYWKMDEGKGNAFVDCTGHGYDLVAGGTLVWKE
                     HVRFDKQ"
     CDS             1657..2670
                     /locus_tag="ctg189_10"
                     /transl_table=11
                     /translation="MNRHLNFVTLICLITGFVSLASCSNDDDEMDKYQKIYIRTGVAPG
                     AEMGAAVVVDCVSNSSTADRSDFEIQLCAVQPVTRDVTAALGVDTLKVDTYNSANKTKC
                     KLLPQDNYTIETSEVVLKTGQTVADSSFQVVLKNIEKLTNPDGYVLPVALKGVMGMDEQ
                     AVSTSMKTVYIRIYTSVLYTSYTKPGNWSAVDRSAWSVSCSNVYADDDAKYGAHLAIDG
                     EINTTWFTWGVANAGECWWNTVLDRPVTLTGFSVTKQSAYGSGYNLRSAEIKVRKEGET
                     EWVTYPRVLTFRNFKGADPQYAAIEPPIPNVKEFRINCLTPDNYTGFAEINLYVKQ"
     CDS             2920..4188
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg189_11"
                     /sec_met_domain="MFS_1 (E-value: 1.3e-11, bitscore: 34.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKPISPVCWVPTVYFAMGLPFVALSMVSVLMFSDMEVSNAQIA
                     FWTSLIMLPWTLKPLWSPFLEMFKTKKYFVVATEIITGLAFALVALSLPLPDFFRYAIA
                     LMGIIALSGATHDIAGDGVYLTELTATQQAKYIGWQGAFYNLAKILANGGLVWLAGMLK
                     DEFGVVHAWMIVMLMCAGIMILIGLYHIRILPSGGGASGEVNTMSDALNMLWEVIRSFF
                     QKKHIAFYIVFIILYRFAEGYAIKIVPLFLKASVADGGLGLSTQDIGLVYGTFGAGAFI
                     LGSLLAGYYISAFGLRKTLFSLCCAFNIPFLVYFLLALYQPSDLWIIGMAIVSEYLGYG
                     FGFVGLMLFMMQQVAPGKHQMAHYAFATGIMNLGVMLPGMMSGYLSDWLGYRDFFIWVL
                     IATIPAFIVTWLVPFTYPDGKKK"
     CDS             4243..5028
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_130"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg189_12"
                     /sec_met_domain="Glyco_hydro_130 (E-value: 9.3e-45,
                     bitscore: 143.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKIAGAALPAMPWEERPAGCKDVVWRCSANPIIPRDLLPTSN
                     SIFNSAVVPFKDGYAGVFRCDDTNRRMRLHVGFSKDAVHWDINEEPLKFQCDDAEVGTW
                     VYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTYDFVTFHQLENAFIPFNRNGVLFPRK
                     INGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAPFEDSAWQCTKIGAGP
                     IPIETSEGWLLIYHGVLASCNGFVYSFGSALLDIDQPGK"
     CDS             complement(5322..5795)
                     /locus_tag="ctg189_13"
                     /transl_table=11
                     /translation="MKTLNYTHLEEKGANTIVLSLQQLLADFQIHYANLRGFHWNIKGH
                     GFFVLHSKFEDLYNGAAEKVDEIAERILMLGGTPANKYSDYLKMAQIKEVDGVNKADDA
                     LNHILETYGHLIAEERKILSLASSHNDEVTVAMMSDYLKEQEKMVWMLTAYNG"
     CDS             5865..6674
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     57.5; E-value: 3.3e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg189_14"
                     /sec_met_domain="LysR_substrate (E-value: 7.1e-31,
                     bitscore: 97.6, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.1e-18, bitscore: 57.5,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVKLKISIFALIDSISLINQRTMTIQQLEYILAVDQFRHFAKA
                     AEYCRVTQPTLSAMIQKLEDELGVKLFDRSMTPVCPTAIGKKVLEQARKILSEVICVKE
                     IISEEQHSLSGTFRLAVLPTIAPYLLPRFFPQLMEKYPDLDIRVMELKTPDIRKALLTG
                     EVDAAIIASMLDDAALTEETLFYEQFLGYVSKKEPLFKHDVIRTSDVTGERLWLLDEGH
                     CFRDQLVRFCQMEAVKISQMAYRLGSMEPLCIWWRVVRGLRLFPNWQ"
     CDS             6620..6862
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg189_15"
                     /sec_met_domain="LysR_substrate (E-value: 3.3e-12,
                     bitscore: 36.6, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHMVESGKGITFIPELAVMQLSEEQKELVRPFAIPRPTRQIVLVT
                     RKDFIRTSLLQVLKEEIQAAVPKEMLTLQAVQCLV"
     CDS             complement(6967..7719)
                     /locus_tag="ctg189_16"
                     /transl_table=11
                     /translation="MKKFNLITFAVILMLLPILQSCLDDANNDEWVTCPPGGILAIGTM
                     KIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFVGYLQMGEEKPGYENG
                     KIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIEYQYLGSMNENKKHML
                     NLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDSIAEQLATAKGIKLRV
                     NTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             7907..8455
                     /locus_tag="ctg189_17"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LVHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTALQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEAIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             8510..9769
                     /locus_tag="ctg189_18"
                     /transl_table=11
                     /translation="MKEDEKWIKAFKDKLEDYSEPMPASGWERLERELMPVTEKRIYPY
                     RRWAVAAAAVVLVVTTAVSLYFLNSPVADEIRYATAPSLAVNPDVLPEPALPDVQVAVS
                     EPVKPVGTTSINPVSGYLAKNTDPVIVPEVSSLAEKRPEAVTEEKRTEPQQEATAAIEK
                     KESATAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGKWSMGVGIGNGGGLPTNGSENFA
                     PRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVMDYEHHQPVSFGLSVRK
                     SLPKGFSVETGLTYTLLSSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYFTLYVSA
                     GGMVEKCVYGKLADDKVNVKPLQFSVAGAVGAQFNATDHVGLYVEPGVSYFFDDGSKVQ
                     TIRKERPCNFNLQAGLRFTY"
     CDS             complement(10001..10726)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.3;
                     E-value: 1.6e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg189_19"
                     /sec_met_domain="Radical_SAM (E-value: 1e-30, bitscore:
                     97.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKEAGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTAAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQMIQRVEILPYHTLGVHKYEAMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFRTVQVN"
     CDS             complement(10731..11783)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg189_20"
                     /sec_met_domain="Gly_radical (E-value: 2.1e-47, bitscore:
                     150.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 2.6e-122, bitscore:
                     399.5, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREVRQSDDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGG
                     RCENTGTVMVKDIPVLTGETLKFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEK
                     AQMAFVDTDPRINLAYGVAGLSIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFG
                     NDDDRVDHLGVDLVYFFSEELKKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKG
                     IAFAPGANPMHGRDKNGAIASLSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNL
                     VTMMDGYFTKGAHHLNVNVLNREMLQDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLE
                     VISRSFHERM"
     CDS             complement(11783..12958)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg189_21"
                     /sec_met_domain="PFL_acetate1 (E-value: 3.9e-212, bitscore:
                     696.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRDFVSNNITPYEGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYTTVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEASKHSVHKYLSTLLPYNTKTTT"
ORIGIN
        1 tgctcacttt cgtgaaagca ctgggagaaa gaatcggacc taaatcgggt acgggacggt
       61 tacttgtgat tgatggcgag ctcaaagtat tcatccggaa accgggcctt actttgacta
      121 tttcattgtg caggcatact ctaaccttgc gggtaattcc gatgctaatc ttgacagacg
      181 tctggctggt acgattgcca actttaaagg aatacttcct ccggagaaag tggctaatat
      241 gtacatcgtt acggagaatt tcgaatctta tgctccgaca ggaggaggtg attatgtaga
      301 tcgttacgga aacaaaatga gagcacttgc cggcatggca cgctggactc cgactattga
      361 cggaaaacag gtacggaagg gtggagtagg cacctatcac atggaatatg actatccggg
      421 cgacatcgaa tataagtacc tgcgtgaagc aatcagaata atgaatcctg ctgtaaaatg
      481 actttaaaga atttgattat gaaaagaata acaataaaac aatatttgct tgcctgtttc
      541 gttctgccga tgatcttggc aggatgcaac gatgccgatt accaggttat cgacaatgcg
      601 atttatttga atgaagcatc cgagaatggt tcggcaaagg ttaccgttga tcctgaaaat
      661 gtaacaacaa ctactctgac cgtacgtgtg ggacagcctg taaccgaaaa tgtgactgct
      721 gtcctgacgg tagatccttc tattcttaaa gagtacaatg aagctaatga aacttcgtac
      781 gaagtccttc ccgagcagta ttttacttat gacaaagaga taaagatagc ggcaggcgat
      841 gttagcgcaa tccccagtga gtttagagtg aaaccttatt caaacgaaaa cggagaattg
      901 tatgctattc cggtatctct cacagaaatt cagggaccgg tgtccacaat cgggctttcg
      961 tcgaagttta tcattttgct ggataagccg ctgatacagt ctgtaccgtt tatgaatacg
     1021 accaatgccg tgaagcccgc caaggacgaa ttgtggggag tgacaaccaa tgaatggtca
     1081 ctcgaggctt gggtacagat ggacggattc gatattaata atcaggctat atttaattcg
     1141 ggcagcagcg accacgaggt ttatatccgt ttcggtgacg ctatgatccc ttataattca
     1201 ttacaggtga agacacttgg aagtcaggtc aatacggtga ctttgtttga gaagaataag
     1261 tggtatcatc tggcctcgtt tataattctt ccgggttatt gtcgatttat atcaacggag
     1321 tgctcgacgt gactctgcag acaaagggtg gcccggttag attcgacaag atgaacatgg
     1381 tttcgagcgg tagctacttc cgcaacaatt gtcagatggc ccaggtgcgt ctttggaaga
     1441 gcgcaatcag ccagacgcaa attcagtcca acatgtattt tgccgtgaag cccgccgatc
     1501 cgaacctgat aggctattgg aaaatggatg aaggtaaggg aaatgccttt gtcgactgta
     1561 ccggacacgg atacgatttg gtggcaggag gaactcttgt ctggaaagag catgttcgtt
     1621 ttgataagca ataactatgt aaaaagaaga taagatatga atagacattt gaattttgtg
     1681 accttaatct gcctgataac aggctttgta tcgttggctt cgtgcagcaa cgatgatgat
     1741 gaaatggaca aatatcaaaa gatatatatc agaacgggag ttgcaccggg ggccgaaatg
     1801 ggtgctgcgg tagtggtgga ttgtgtgagc aattcctcta ctgccgaccg ttctgatttt
     1861 gaaatacaat tgtgtgccgt acagccggtt acgcgggatg tcactgccgc tttgggagta
     1921 gatacgctga aagtggatac ttacaattct gccaataaga cgaaatgtaa gttgttgccc
     1981 caagataatt ataccattga aacaagtgaa gttgtcttaa aaacgggaca gacagtggcc
     2041 gattcatctt ttcaggtcgt tttgaagaat atagaaaagt tgactaatcc tgacggatat
     2101 gtgcttcccg tggcgcttaa aggagttatg ggcatggacg aacaggctgt cagtacatct
     2161 atgaagacgg tttatatccg gatttatacc agcgtgcttt ataccagtta tacgaaaccc
     2221 gggaattggt ccgctgtaga tcgaagtgcg tggagtgtaa gttgcagcaa tgtttatgcc
     2281 gatgatgatg ccaaatatgg tgcacatctg gctattgacg gtgagataaa tactacttgg
     2341 tttacatggg gagtggctaa tgccggagag tgttggtgga atacggtact ggaccggcct
     2401 gttaccttaa ccggattttc ggtcactaaa cagagtgcct acggatcggg ttataatctg
     2461 agaagtgctg agattaaggt tcggaaagag ggtgaaaccg agtgggttac ttacccgaga
     2521 gtcttgactt tcagaaattt taaaggggct gatccgcaat atgcggccat cgaaccacct
     2581 atcccgaatg taaaggaatt cagaataaac tgtctgactc cggataatta taccgggttt
     2641 gctgagataa atttatatgt gaagcaatag aggtgtttag attgtagata agggggcgag
     2701 aggcatcggg gatgaaagtc ttcggtgctt ctttgcgtgt gtcgtattga taaagtttaa
     2761 taaaaaaagg gtgatagagg ttagtagttt tcccgggtga gttgtattat taaataatga
     2821 aagcaacttc ttgtcgtaat cttgggttat gtttttaata tcccctatct ttgcttactg
     2881 gaattgttaa ccgatggaat tattataaaa aactaactga tgaataaaaa gccgataagc
     2941 cctgtatgtt gggtgcctac tgtttacttt gctatgggat tgccgtttgt ggccctttcg
     3001 atggtttctg tccttatgtt ttccgatatg gaagtgtcga atgcacagat tgctttctgg
     3061 acttctctca ttatgcttcc ctggacattg aagcctttat ggagtccgtt tctggaaatg
     3121 tttaaaacga aaaagtactt tgttgtcgct acggaaatta ttaccggact ggcatttgca
     3181 ttggtagcac tttcgctgcc gctgcccgac ttttttcgtt atgccatcgc tctgatgggg
     3241 atcattgctc tcagtggtgc gactcatgac attgcggggg acggagtata cctgactgaa
     3301 ctgactgcta cccagcaagc caagtatatc ggttggcagg gagcttttta taatctggcc
     3361 aagatacttg ccaacggagg cttggtttgg ttggcaggta tgctgaagga tgaatttgga
     3421 gtggtacatg cctggatgat tgtcatgttg atgtgtgcgg gtattatgat tctgatcggt
     3481 ctttaccaca tccggatttt gccttcggga ggaggcgctt ccggtgaagt gaatacgatg
     3541 agtgacgcat tgaatatgct ttgggaagtc atccgctctt ttttccaaaa aaaacatatt
     3601 gctttctaca ttgtctttat cattttgtac cggtttgccg aaggatatgc catcaagatt
     3661 gtaccgttgt tcctgaaagc gtcggttgcg gatggtggat tgggactcag cactcaggat
     3721 atcggactgg tatatggtac gttcggagcg ggagctttta ttctcggttc gcttttggcc
     3781 ggttattaca tttcggcttt cggacttcgg aagactttgt tttctttatg ttgcgctttt
     3841 aatattccgt tcttggtata tttcctgtta gccctttacc agccttccga tctatggatt
     3901 attggtatgg ccattgtgtc tgaatacttg ggttacgggt ttggttttgt cggattgatg
     3961 ctctttatga tgcagcaagt ggctcccggc aaacatcaga tggcacatta tgcttttgct
     4021 accggtatta tgaatctggg cgtgatgctt cccggaatga tgagcggata cctgagcgat
     4081 tggctgggtt atcgcgattt ctttatctgg gtacttatcg ctaccatacc ggcttttatc
     4141 gtgacttggc tggtaccttt cacatatccg gacggaaaga agaaataaaa agagattttc
     4201 aatataaaca agatatatac ataatattaa tttaatcgaa tcatggaaga aattaaaatt
     4261 gcaggtgctg ctttgccggc tatgccttgg gaagaacgtc cggcaggatg taaagatgta
     4321 gtgtggcgtt gttcggccaa tccgattatt ccgcgcgact tgctccctac ttcaaacagt
     4381 atattcaaca gtgccgtagt tccgtttaag gatggctatg caggggtgtt ccgttgtgat
     4441 gatactaatc gtcgcatgcg tttgcatgtg ggattcagca aggatgctgt tcattgggat
     4501 atcaacgaag aaccgttaaa gtttcaatgt gatgatgctg aggttggaac ctgggtctat
     4561 ggatatgacc cacgggtttg ctttatcgaa gaccgctact atgtgacctg gtgtaatggc
     4621 tatcatggtc ctactatcgg tgtggcctac acctatgatt ttgttacttt tcaccagttg
     4681 gagaatgcct ttattccttt caatcggaat ggagtcttgt tccctcgtaa gataaacggt
     4741 cgttttgcga tgttgagccg cccgagtgat aatgggcata ctccttttgg agatattttc
     4801 tatagcgagt ctcccgatat ggagttctgg ggacgtcatc gtcatgttat gtcgccggct
     4861 ccgttcgaag acagtgcctg gcagtgtacc aagatcggtg cagggcctat cccgattgaa
     4921 acctcggaag gctggttact gatctatcat ggtgtattgg cttcctgcaa cggttttgtg
     4981 tatagttttg gttcggcact gcttgacatc gatcagcctg gaaagtaaaa ttccgttcgg
     5041 ggccttatct gatttcacct cagaaggatt acgaatgtat gggtgatgtg cctaatgtct
     5101 gtttcccatg cgcagcgctt catgattcgg agaccggacg gattgccatc tattatgggt
     5161 gtgcggatac agtgaccggg ctcgcattcg gatacattcc ggaaattatt gaatttacca
     5221 aacgtacaag tatcatctga atcgaataaa acagaaaggg tgtagctatc ccgccgggat
     5281 ggctacaccc ttttgcttgt atggctacac cctttcggct gttatccgtt gtatgcagtc
     5341 agcatccaaa ccatcttttc ctgttctttc aggtagtcgc tcatcatggc cactgttact
     5401 tcgtcgttgt gtgaagaggc gagagacagg attttacgtt cttccgcaat cagatgcccg
     5461 taagtttcga gaatatgatt cagagcgtcg tcggccttat tcactccgtc cacttccttg
     5521 atctgcgcca tcttcagata gtcactgtat ttattggcgg gagttcctcc cagcatcagt
     5581 atacgttcgg ctatttcgtc caccttttcg gcggctccat tatataaatc ttcaaacttg
     5641 ctgtgcagta cgaagaaacc gtgtcctttg atgttccagt gaaatcctct caggtttgca
     5701 taatgaatct gaaaatcggc aagcagttgc tgtaatgaca gtacgatggt gttagctcct
     5761 ttttcttcca aatgtgtata atttaaagtc ttcataatga tattgttttt tttgagttaa
     5821 tactatattt cttcttttta tctggaacaa agatacggca caaaatgatt cgtgtcaaac
     5881 tgaaaatttc tatctttgca ttgatagatt ctatatcttt aataaatcag agaacgatga
     5941 ctatacaaca attggaatat attctggctg tggaccagtt ccggcatttt gctaaagctg
     6001 ccgagtattg ccgggtgacg caacctactt tgagtgcaat gatccaaaag ctggaagacg
     6061 aattgggggt gaaactgttc gaccgtagca tgacaccggt ttgccctact gccattggta
     6121 agaaagtgct ggaacaggcc cgtaagattc tttcggaagt tatctgtgtc aaggagatca
     6181 tcagcgaaga acagcactcc ctgtcgggta cattccgatt ggcagtgtta ccgacgattg
     6241 caccttatct tctgccccgt ttctttccgc aactgatgga gaaatacccg gatcttgata
     6301 tacgggtgat ggagctgaag acgcccgaca ttcgcaaggc tctgctgacc ggtgaagtgg
     6361 atgctgctat cattgccagc atgctggatg atgccgcatt aacggaagag accttattct
     6421 acgagcaatt cctgggctat gtctcaaaga aggaaccgtt gttcaagcac gatgtgattc
     6481 gtacgtccga tgtgacaggg gaacggcttt ggcttcttga cgaagggcat tgcttccgcg
     6541 atcagttggt tcgtttttgt cagatggaag cggttaagat cagccaaatg gcgtatcggc
     6601 tgggtagtat ggaaccttta tgcatatggt ggagagtggt aaggggatta cgtttattcc
     6661 cgaactggca gtgatgcaat tgagcgaaga gcagaaagaa ctggtccgtc cgtttgctat
     6721 cccgcggcct acccgtcaga ttgtcctggt gacccggaaa gacttcatcc gcaccagtct
     6781 gctgcaggtt ttgaaagagg agattcaggc ggcggttccc aaggagatgc ttaccctgca
     6841 ggccgttcag tgtctggtat aatataaaaa cgacggcgat attttcacaa acatcgccgc
     6901 cttatttctt ttatgtatca gaattattac tcgttttgcc tgattgtgta ggtgtttctt
     6961 gttgttttat tgagaatgaa atgattttat ttttaagttt ttgtcttcgt tgatatctat
     7021 tgtgacatac tgtatattgt cataaatggt gttcacacgg agttttattc ctttggctgt
     7081 cgccaattgc tcggctatac tatccagctt gaaagaaaca aggctcgaac ccaattgatt
     7141 gggggagtca ttaaaggcat tatgccggaa ctccagatag atatatccgt catcttttat
     7201 gggacctgtt atttcgtttt gtaccaagtt cagcatgtgt tttttatttt cattcatgct
     7261 gcccagatat tgatattcga tggtcagata atctttcgta agtgcatgcg ctgtgacgtt
     7321 gatacggtcg tctccaatgc tgtctgctgt agcttccgtc agtggaatga tctctttcgt
     7381 caatatatct tctatcgtga atattttacc gttctcatat ccgggtttct cttctcccat
     7441 ctgcagatag ccaacgaaga ctctttgacc ttctgcaaca gtgtatttcc tgttgcgtat
     7501 atcggccgta tctgccggaa gtacattgtc tccattgtcc aatgcaatga aaaagtccct
     7561 tggagtgtcc gcattgggaa tcttcattgt gccgatggcc aatattccac ccggaggaca
     7621 agtgacccac tcgtcgttgt tggcatcgtc cagacatgac tgtaaaatgg gcaataacat
     7681 caggatgacg gcaaaagtta ttaaattaaa tttcttcata agtttcttgt tggttttatc
     7741 ctatttatcc attgagattt attctttatt gtattgagaa aatgcaggaa gtgatgaaat
     7801 attgcatcct aaaatgttaa agaaacaaaa gtgataaaag agttgttctc tctgtgcagt
     7861 atttctatct ttgctgcatt tataaggtaa acacgtgttt aggagaatga atgaattaga
     7921 gctgtcggaa cgttgcaggc agggagataa tcgtgcccgc aaagaacttt atgagcagta
     7981 cgcagggcgc atgcttggtg tctgtcttcg ttatgccgga gacagggata tggcacaaga
     8041 cttggtacac gacggtttcc tgaagatttt cgactccttc gacaagttta cctggcgggg
     8101 tgaaggctct ctgagagcat ggatggagcg tgtaatggtg aatacggctt tacagttctt
     8161 aagaaagaac gacgtgatga accagaccac ggcactggat gaagttcccg aaacgtatga
     8221 agaaccggat gcttcggctg ttgaagcaat accacagaaa gtgctgatgc aatttattaa
     8281 tgaactcccc gccggatatc gtaccgtatt caatttatac acctttgaag ataagtcgca
     8341 caaggaaatc gcacagatgt tggggattaa tgaaaaatct tctgcctcac agctttttcg
     8401 cgcaaaaagt gtattggcaa agaaagtgaa agaatggttg gtgaccaatg gttgacatgt
     8461 atttacagat actgaggtga accttggatt tcaaaaatga aatagaatga tgaaagaaga
     8521 cgaaaaatgg attaaagcat tcaaggataa gctcgaagat tattcggagc cgatgcctgc
     8581 ttccggttgg gaacgactgg aaagggaact gatgcctgta accgaaaaac gaatatatcc
     8641 gtatcgccgg tgggcggttg ctgcggcagc tgtggtattg gtggtaacga ctgctgtcag
     8701 tttgtatttt ctgaatagtc cggtagctga tgaaatccgt tatgcaacgg ctccttcact
     8761 ggctgtcaac ccggatgtat tgccggaacc tgccttgccg gatgtacagg tagctgtatc
     8821 cgaacccgtt aagccggtag gaacgacgag tatcaaccct gtttcgggct atttggcaaa
     8881 gaatactgat ccggtgattg ttccggaggt atcctccttg gcagagaagc gaccggaggc
     8941 agtgacggag gaaaagagaa ctgagccgca acaggaagca actgctgcaa tcgagaaaaa
     9001 agaaagtgcg acggcgcagc ctccaaagag gaaagaagcg cggcgaccgt ccggtaaaga
     9061 caagtatcag ttgcctatcg gagactcttc tgctaaacgt ggtggtaaat ggtcgatggg
     9121 agtgggtatc ggtaatggag gtggacttcc gacaaatggt tccgaaaatt ttgcgccccg
     9181 tccgatgact aacagggtcg acttgatgac gatcatgaat ggagctgtga gtattcctgc
     9241 cgatcaggaa gttatatttg aagaaggggt tccctatctg aagtccaata caactgccgt
     9301 gatggattat gaacatcatc agccggttag cttcggactg tctgtacgta agtctcttcc
     9361 caaaggtttc tctgtagaga cgggattgac ttatacgttg ttgtcttctg acatcaaacg
     9421 gcagggggat accaagatgc agagtcagaa attgcattat ataggtattc ctgtacgtgg
     9481 aaactggaat tttctggaaa agaaatattt tacactctat gtatctgccg gaggaatggt
     9541 tgaaaagtgt gtttatggaa agttggcgga tgataaggtg aatgtgaagc ctttgcaatt
     9601 ttctgtagcc ggtgccgtgg gagcgcaatt caatgcgaca gatcatgtcg gcctatatgt
     9661 ggaaccggga gtttcgtatt tctttgatga tggctccaaa gtacaaacca tccgaaaaga
     9721 aaggccttgt aactttaact tgcaggcagg attgcgattc acttattaaa gtaggatggc
     9781 aaaaaatata ccggttacat tatctccctg ttcttgcctt gtattgtaat gaattaaggc
     9841 aagaacaggg agatttttat gtcgtgactt acaaaattat aaataagcgc aatcgtcata
     9901 atttaccgca gagtgaactt aatctattga ttgccaatga tctttatctg tgtaaattcg
     9961 tgtaatctgt ggcgaatacg aatttcgaca cttatataag tcaattcact tgtacggtcc
    10021 ggaaatattg cctgaatagt ttctcagcct tttctatctg ctccggagta ttctctttca
    10081 ctcctttcag catatattct ttgttcattg cttcatattt gtgaacaccc aaggtgtggt
    10141 aaggcaatat ttctacacgc tgaatcatct ggtacgttcc aagatgctct cccagctgcc
    10201 ggatatcgtc ttcgaagtca ctgtagccgg gcactaatac gtatcgcaac cagaatggtt
    10261 tatgattggt ttcaagccag gctgcggttt tcagggtctg ctcgttgctt cttccggtta
    10321 aagactgatg atgttccgga ttaaattctt tgatatctaa taaaaccaga tcagtcaatt
    10381 ccaatagttc ctctacatca ttgttccata gcccgccatt ggtatcaagg caaatatgga
    10441 ttcctgcttc ctttagtctt ttaaaaagtg ggataagcga ttttgcttga aaagtaggct
    10501 ctccgccgga aaaggtgata cctccctttt taccgaagaa agctttctga ctgacggcca
    10561 tgcgaactat ttcctcaggg tcggttgctg tccctccttt ggcttcaatt gtgtccggat
    10621 tggcacaata gaggcaacgg aagttacacc cttgaaggaa aacgacgagc cggagacccg
    10681 gcccgtcgaa tgttcccatt gactcgtatg agtgtacgtt tatcattcaa ttacattctt
    10741 tcgtggaaac tgcggctgat tacttccaac tgatgttcgc ggctcaattt cacgaaatta
    10801 acggcatatc ctgagacacg gatagtcagt tgcggatact tttcgggatg ttccatcgca
    10861 tcctgcaaca tttcccggtt cagcacgttt acgttcaggt ggtgtgcgcc ttttgtaaaa
    10921 tatccgtcca tcatggtcac cagattgtcg atacggtctt cttgtgttgc tcccaatgat
    10981 ttgggaacga tcgagaacgt attgctgata ccatcctgtg agtcgcgata acgcaacttg
    11041 gctacagaac tcagtgaggc gattgcacca tttttatcac gtccgtgcat ggggttggca
    11101 ccgggagcaa aggcaatgcc tttggcgcgt ccgtcaggag tggcaccggt cttcttgcca
    11161 tacattacgt tcgaagtgat agtcagcagc gaaagggtag gacgggcatt cttatatacg
    11221 gggagtttct ttaattcttc gctaaagaaa tataccaggt ccacacccag gtggtctaca
    11281 cggtcatcgt cattaccgaa acaagggaaa gcaccttcga tatcgaatcc ctccgtcagt
    11341 ccgatgtcgt tgcgacgggc tttcacatgt gcatatttga tggcggacag tgaatcgatg
    11401 gcgattgaaa gtccggctac accataagcg aggttaatgc ggggatcagt atccacgaaa
    11461 gccatctgcg ccttttcgta gtaatactta tcgtgcatgt aatgtatgat attcattgct
    11521 tcgttgtata cacgtgcaat ttgtatcaat actttcttat agttggccat tacttcttcg
    11581 aacttcagtg tttcaccggt caatacaggg atgtctttta ccataactgt acctgtattt
    11641 tcgcaacgtc ctccgttgat agccagtagc agggctttgg caaggttggc acgtgcgccg
    11701 aagaactgaa tctgctttcc gatttcctga tatgaaacac aacaagcgat tccgtagtca
    11761 tccgattgac ggacttcacg catcaggtcg tcgttttcgt attgtacgga agaagtgtcg
    11821 atagatactt gtgcacagaa tgctttgaag cctcgggtaa ctcagggctc catagtacag
    11881 tcatgttagg ttccggtgac gggcctaagt tataaagtgt ctgcaagaag cggaaagaag
    11941 ttttagtaac tttggtacgt ccgtcattga aacgtccacc gatagattcg gtcacccatg
    12001 tgggatcacc cgcaaaaata tcgttgtacg actgcatacg caagtggcgt accatacgga
    12061 gtttgataac gaattggtcg atcagttcct gagcgaatgt ttcggttatc gtaccctggc
    12121 ttaattcata ttcaagatag atgtcgagga atgaagatac attacccagt gacatggcag
    12181 caccatcctg ctcttttacg gcagccagat aagccatata cacccattgt acagcttcct
    12241 gtgcggtata tgccggtcgg ctcagatcca aaccataata ttcgcccaat actttaatct
    12301 ctttcagggc cttgatttgc tcggctactt cttcacgaag acgaatgcgg gcttcagtca
    12361 taggacctgt cagattatgc agatcttctt ttttagcttc tatcagacgg tcaagaccat
    12421 agagagccag gcggcgataa tcaccgatga tacgtccgcg tgcatagttg tcgggaagtc
    12481 cggtaaggaa tcccaatgaa cggaacgaac gaatttcttc ggtatacaca tcgaataccc
    12541 catcattgtg agtcttgcga tagtgagtga agatatcctt aactctgtca tctacttcca
    12601 ctccgttttc acggcaagct ttcataacca cattgattcc gccaaacggt ttgatggcac
    12661 gttttaacac ctgatcggtc tgtagtccga cgatcagttc gttttcttta tcgatgtagc
    12721 cggcagggtg agaggttata gtagatacag ttgtgtagtc gagtgcacga ataccattat
    12781 tgtttctctc ttcttcgaga gctttgagac agtgattcca gacagctttg gtgcgttcgg
    12841 taggtccttg caggaaagaa gcatcccctt cataaggagt gatgttgtta ctaacgaaat
    12901 cccttacatt gatttctttg ctccaaagtc catctttaaa ggtcttattc agttccataa
    12961 aattaatcag ttagtggtta gttatccttt agcgcgcgca aatttacaac cttttttcgg
    13021 tttaggtata taaaagggtc ctattttatg ttgaatagca taaaaatacc tatttatggg
    13081 gagaagccag atagcagtta ttacttccaa atatactttt ctaatatttt tttgcggaat
    13141 aatttgcaag ttaaaaaatg attcgtacct ttgcagcgct ttaagagaaa agcactactt
    13201 aaccgtagtt ctggagaggt ggcagagtgg tcgattgcgg cggtcttgaa aaccgttgta
    13261 ctgcgaggta cccggggttc gaatccctgt ctctccgctg aaaacaaaaa aacaaagtta
    13321 taagtctgaa tttcaataat tcaaggactt tcttttttta gtatataaca tatcagtctg
    13381 cataataaag aacgaggagc aacgtagatc aatgataacc cttgaggacc taccttgtat
    13441 gtagaatagt gggaaaatcg attttatttg ttccgctact tgagcagatg tcattaccac
    13501 accgccggtg tctagttgta aatgcaatag ttgaggcctt ttatatagac cgttggcttg
    13561 aacgttactt tttaaggagc aacacacatt atcaaagttt atcaatcaaa gcaaggttct
    13621 attttttgta ttccttttgt aagatatata gtcgggctat tcctttattt cagcgttttg
    13681 ctatcctcta attcattata ctacattctt ttttactttt ttctatatat cagtaattga
    13741 cctgaggtcg acattattta aaagattttc agttgccgtc atttgtgaaa tttacaccaa
    13801 tgactgttgt tttttaaaga gacaataaac ggtaatggct gatagcgtgt tggctatgaa
    13861 atgaatacta actttatctt cggtgattat agtggtaagt tgttaaatct tatgattaaa
    13921 tattctaact taaatgattt tattgctgta ttcctatttt tttaagataa cagattg
//
