LOCUS       c00033_gnlPro..        14820 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FAFLPBEM_33.
ACCESSION   c00033_gnlPro..
VERSION     c00033_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 23:17:30
            Original ID  :: gnl|Prokka|FAFLPBEM_33
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14820
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14820
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2093:4820]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2094..4820
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14820
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14820
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(168..704)
                     /locus_tag="ctg33_1"
                     /transl_table=11
                     /translation="VVYPDSPAEKVAMNERLEINIGTTSLPGYYIDYHTTIRLASPSPI
                     TMEAYRYGGICIRTREDWNDQTAEMLTSEGLSRDEADGSRARWCYYQGKAGNEKACILI
                     VASPSNLNYPEPLRVWDKTVNKPAGDVMWNFSPTKQKAFTLEPGKELSLSYRIYVLDKN
                     INATTAEVLSDFERD"
     CDS             741..1016
                     /locus_tag="ctg33_2"
                     /transl_table=11
                     /translation="VFEVAEANCSLFFVEIPEIDLVSFERGFRPGIPQTEMMVMVGGRT
                     IGHHFASQCLQRMDETAAFIDRVNARGWVNRGIVVREQQFISYLIV"
     CDS             complement(1147..1356)
                     /locus_tag="ctg33_3"
                     /transl_table=11
                     /translation="LYLEISSNLWLLSCKGMLNPHITQTIKEIFHQLERCLLAGFICIR
                     YHKRIVRNEKISFFCSRYRQGLAG"
     CDS             complement(1465..1926)
                     /locus_tag="ctg33_4"
                     /transl_table=11
                     /translation="VNRRPETVSQVKPQSNEPDQIQHRIHNIALEVEIDKRCTILRMNV
                     TMNTCQFGKHHVVPELSKVQNHEQDNDHTQNKHVLRSPFNTFRTSVDGITVVTASLTIL
                     QSQDNSIHEVHDYTCSQHQCTEQSIPVRTQQTANHVIRFTRKYCRNVHT"
     CDS             2094..4037
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.4; E-value:
                     1.1e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_5"
                     /sec_met_domain="FAD_binding_2 (E-value: 7e-60, bitscore:
                     194.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 4.5e-38,
                     bitscore: 121.5, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERFAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDFQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFVEAEKAINARIAKLMNVKGKETVDSIHRKLGHI
                     MWEHVGMARDAEGLKEAIQMLKDLKKEFWSNVFIPGEANSLNVELDKALRLADFIEIGA
                     LMAHDALDRAESCGGHFRTEHQTEEGEAMRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     QFVVPQTRNYKK"
     CDS             4065..4820
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_6"
                     /sec_met_domain="Fer2_3 (E-value: 2.9e-26, bitscore: 83.0,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 8.5e-12, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 9e-06, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKGPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANAIPISKADADLAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFISAKLQD"
     CDS             4831..5016
                     /locus_tag="ctg33_7"
                     /transl_table=11
                     /translation="MYVYGKARRQWQRAFFMFVQTHKKAALPIIKVDAAFLLLSSETVS
                     RFPLCKDFVNLRSKIL"
     CDS             5013..5171
                     /locus_tag="ctg33_8"
                     /transl_table=11
                     /translation="MKKTHCKYKVYLLNTQEFVITFYCKFATFCFKIDTVCGFTLLLYQ
                     QSIDSDT"
     CDS             complement(5144..6175)
                     /locus_tag="ctg33_9"
                     /transl_table=11
                     /translation="MKIGTIDLGERPVFLAPMEDVTDISFRLMCKRFGADMVYTEFVSA
                     DALIRSVNKTQQKLNVADEERPVAIQIYGRDVPTMVEAAQICEAAHPDILDINFGCPVK
                     RVAGKGAGAGMLRNIPLMLDITREVVKAVNIPVTVKTRLGWDADNRIIVDLAEQLQDCG
                     IAALSIHGRTRAQMYTGEADWTLIGEVKNNPRIQIPIIGNGDVTSAEICKQRFEQYGVD
                     AVMIGRGSIGRPWIFREVRHYLDTGETLPAESFSWYLDILKKQVEQSVERLDERRGILH
                     IRRHLAATPLFKGIADFKQTRVAMLRAETVEALFDILDSIPDKFHTGYGFQSDSQVSES
                     IDC"
     CDS             6281..6691
                     /locus_tag="ctg33_10"
                     /transl_table=11
                     /translation="VLLNNIVVFVHSSNKKRIMVRLTSKEEEILGYFWAKGPLFVRELL
                     DLQEESKPHYNTLSTIVRSLEEKGYIGYKVYGNTHQYYALVSEDEYRRNSLKQVISKYY
                     DNSYTRVVSTLIEEEVLTIDELQKLIQQIKNK"
     CDS             6705..7337
                     /locus_tag="ctg33_11"
                     /transl_table=11
                     /translation="MDAFLLYILKSGICLTVFYVCFKALFSNDTFFRFNRWILLVGTGV
                     CMLLPLCRIQTARPFPLSRPVSQLEIVFYEEEMKAFPVPESKEEITIPTEQRNISVPWT
                     GIIGIAFLTGSGICLTTTILSFGKMYQLTRKNRKLKQGKYTLILTPDPVSPFSWGRYIF
                     LSENDYRNHPNEILMHEKMHLRYNHSVDLIYMKRFFFCNGLILPYGY"
     CDS             7427..8473
                     /locus_tag="ctg33_12"
                     /transl_table=11
                     /translation="VKKAVGSSLYTLANSFNHSKIKKRITMMLKKKSNNWARLKLALLV
                     PVGFAALSAFARPETSPPPAATMTDNIHLSINKSTVNQETMQQDHAVFLTYKESGSEDL
                     NSIVCKTLDRIRTRVAEGQFKNALEVTVNPAFDDIPASYLETVKDVLEERDIKCKIDMT
                     VPNTIMDDVAKPYRKYDDVVYLIQNKKIVAALSISKFSANQNDPRLDKISKSASLILQP
                     ENPKVSRQEMEKLKNLLDKKGLTSEINMNIFKIGDAAAPPPPPPAGQVIFSYRDGQPDQ
                     QFVLYDRHAKPGANLGQRIDKIYKDNITKVSIKINKSTPKDLLETVKQELKKKINYPVQ
                     YEILQFVD"
     CDS             8585..9820
                     /locus_tag="ctg33_13"
                     /transl_table=11
                     /translation="MIHNVKILFFICFFTACSSTEQKEIVTAGELLRQAAFYGERLQFL
                     PALETYQQAIKLAEKEKDSTVFSLAYLEMGKIYRYQSLKQKALQSEKKALSYIKSPACD
                     SLRLELYREIGDMYTLSGQADSAFHYYEMAGCRIKQAKILQQNGSNKEAETLLKTELEQ
                     TIFPKEKAEVCLALADLQITLGKLDEAEKSLSQVPPSHPHLYAALSRIAQSRGDSLQAD
                     FYHKSYLHHLSVLRQEKEQNQITQLLRTSEQKEWEKRLTDSQKAQKEQIYVWVTLLVSC
                     STGIWGYSRYRQKRNVVSLSETDFFSSEIYLRFHRKEEWKPVPKDWEELLQAFNRTYPD
                     FRERLKRKIPKLSEQEWRMCCLIKMEVPPSTAAMLLCCTNQAISMRRVRLYQKITGEKG
                     TPELCDSFIRDF"
     CDS             9887..11083
                     /locus_tag="ctg33_14"
                     /transl_table=11
                     /translation="MKKMLFGLMTAIATFTGCESKQPAGELPRIDLTATSFAFDQVEIA
                     DEIESIEYVPLELTDESLIADVLDLCVSDEYIFVYSTRQDGVLQFDRKGKYLRCIAKTG
                     NGPGETGQIISLTVDEENRLFCVSEYFSTSFYSFDGEFIKKIENPRPYSYQFSVGPNTM
                     AELGRMYVPMNTPGMFSLGVFNWGTDDTIAFRHTIGDMDLMPLEETSLKGWIFSGSKDG
                     ILCYSEGIDTVWDVNARNIAPAFLINTGYSVEEEKEMRSSKTGNEAVDGKYSVFSFFET
                     PRHYFVKCFEGSNQSKFYLYGLDKATGELKRETSPLNAQELFKNNWTLAGIGFRNTKDN
                     GLPIWPYLSYPGKKQMVQFNTAVEIEYLKEKYPDLKKHLVLQQITEDSNPLITIYHLR"
     CDS             11138..12397
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_15"
                     /sec_met_domain="Peptidase_U32 (E-value: 3.9e-69, bitscore:
                     223.6, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNEKDFEIMAPVGSYESLMAAIQGGADSIYFGIEGLNMRSRSSNN
                     FTTDDLRKIVALCREHGIKSYLTVNTVIYGEDLPLMREIIDAAKEAEVSAIIAADVAAM
                     NYANSIGQEVHLSTQLNISNAEALKFYARFADVVVLARELNLKQVHEIYRQIVDQQITG
                     PKGELIRIEMFAHGALCMAVSGKCYLSLHEMNASANRGACMQICRRAYSVKDKDSNIEL
                     DIENQYIMSPKDLKTIHFMNKMMDAGVRVFKIEGRARGPEYVRLVTECYKEAVRAYCNG
                     TFDEKKVAAWDERLRSVFNRGFWDGYYLGQRLGEWSSKYGSGATKKKVYVAKGIKYFDK
                     IGVAEFEMESGNLKVGDEILITGPTTGAVMQTIEEIRVDLKPVDETVKGERFSLKVNEK
                     IRPSDRLYKMEKVQLEKVFE"
     CDS             12397..12804
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_16"
                     /sec_met_domain="HBT (E-value: 2.4e-08, bitscore: 25.6,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 3.6e-09, bitscore: 28.5,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYIFKLTDKVRDYECDLQGVVNNSNYQHYMEHTRHEFLESLGE
                     NFGKMHEKGVDGFVSRVEIQYKTSLKSGDSYISCLNAYKKGVKLVFEQDIYRASDNALA
                     TKGIVESVIVENGKLTRGEYFDEMLKRIEHT"
     CDS             12849..13916
                     /locus_tag="ctg33_17"
                     /transl_table=11
                     /translation="VGDILARHLLQALGEAEAVFTEKQQLLGRIPGIGSNIAAEIKRPE
                     ILQRAEKELAFIEKNNISCYYLTDTDYPVRLRECPDAPILFYFKGNTNLDATRIISIVG
                     TRNATEYGRELTESLIKDLAKVIPDLLVVSGLAYGIDICAHRNALYNRLPTVAVLAHGL
                     DRIYPSCHRNTAVEMLESGGLLTDFPSGTEPDRPNFLRRNRIVAGISDCTIVVESAEKG
                     GSLVTADIAFSYGRDVYSFPGRVGDSHSKGCNNLIRQNKAGLITSADDLLSALCWDIQA
                     GATPVQTELFFAEAETFTSEQNPVLAIMRTRNEIHINELASVLEIPVHQLSMLLFELEI
                     NGKVKALPGNLYKLS"
ORIGIN
        1 ggggcggata catgggggtg ttgggtaagt tttattacgt gtttttcatt gatttgtagc
       61 tgtatttaca taaaagagcc ttgtctttga tgatatagga gaacaagccc tttttccttt
      121 tcttgtttac cttgccctgc aaattgtcag tttgttttag tagaaattca atcacgttcg
      181 aaatcggaca gcacttctgc cgtagtagcg ttgatgttct tgtccaatac ataaatgcgg
      241 taagacaggc tcagttcttt accgggttcc aatgtgaatg ccttctgctt ggtcggtgag
      301 aaattccaca tgacgtcacc ggcaggcttg ttgacagttt tgtcccatac gcgtaagggc
      361 tcaggatagt ttaggttgga aggggaggca acgattagga tacaggcctt ttcgtttccg
      421 gctttccctt ggtagtagca ccaacgggct ctcgaaccgt cagcttcgtc gcgggaaagg
      481 ccttccgagg tgagcatttc ggctgtctga tcgttccagt cttcgcgcgt acggatgcat
      541 atgccgccat aacggtaagc ttccatggtg atcgggctgg ggctggcgag gcggatagtg
      601 gtatgatagt cgatgtaata acctggtaag gatgttgtcc cgatgttgat ctccaggcgt
      661 tcgttcattg ctactttttc tgcgggagaa tcggggtaga ccacatggtc cagtgtcgca
      721 acaaaaccgt tgtcggatac gtgttcgaag ttgcggaagc gaactgttcc ttgttttttg
      781 tggagattcc agaaatcgat ctcgtttcct tcgaacgtgg ttttcgtcca ggcataccac
      841 aaaccgaaat gatggtaatg gtcggcggga gaacaattgg tcatcacttc gcctcccaat
      901 gtcttcaaag gatggatgaa accgctgcgt ttatagaccg agtcaacgcc aggggctggg
      961 taaaccgtgg tatagttgta agagaacaac agtttatctc ctatcttata gtctaaggtt
     1021 ttccccgtgt cgacgacgga acaggatgtt tcggaaggct gacaagagcc taagaacaga
     1081 gaaatcaaaa aaacaccaat agaaaaaata gcagttttca taatatgaca attaaataat
     1141 aatcagttat ccggcaagac cttgcctgta tcggctacaa aaaaacgaaa ttttttcgtt
     1201 tcgcacaatc cgtttgtgat atctgatgca aataaaacca gccagcaagc agcgttctaa
     1261 ttgatgaaat atttctttaa tcgtttgcgt gatatgggga tttagcatac ctttgcacga
     1321 taataaccat agattggagg aaatttctaa atacaattaa ataacttaaa ttattatctt
     1381 atgtggttac ttaattcttc tatcgggaag aagctgataa tgagtatatc aggtcttttt
     1441 ctcattctgt tcttggtgtt ccacttatgt atgaacattg cggcagtatt ttctggtgaa
     1501 gcgtataacg tgatttgcgg tttgctgggt tctaactggt atgctttgct cggtacattg
     1561 gtgttggctg caggtgtagt cgtgcacttc gtgtatgcta ttatcttgac tctgcagaat
     1621 cgtaaggctc gcggtaacga ccgttatgcc atcaacgctc gtccgaaagg tgttgaatgg
     1681 gcttctcaga acatgtttgt tttgggtgtg atcgttatcc tgttcatggt tctgcacttt
     1741 actcagttct ggtacaacat gatgtttgcc gaactggcag gtattcatgg tgacattcat
     1801 ccgcaggatg gtgcagcgtt tatcaatttc tacttccagg gcaatgttgt gaatacggtg
     1861 ttgtatctga tctggttcgt tgctctgtgg tttcacctga ctcacggttt ctggtctgcg
     1921 attcacacaa ttggctggaa caataccgtt tggttaagcc gttgggaatg tatctctaaa
     1981 tgggttgcca ctattatttg tggcttattc gctgttatca cagttatctt ctacctgaac
     2041 ggtgtaggtg cttaatttcg gatattattt tttcaatttg aaaataaaac attatgactc
     2101 aaatagattc taaaattcct caaggcccgt tggctgagaa gtggacaaat tataaaaatc
     2161 accagaaatt ggtgaatccc gcaaacaaac gtcgtttgga cataattgta gtaggtactg
     2221 gtctggcggg tgcttctgct gctgcctctc tggctgaaat gggattcaat gtattgaatt
     2281 tctgtattca ggactctccc cgtcgtgcac actctatcgc tgcacagggc ggtatcaatg
     2341 cggcaaagaa ttatcagaat gatggtgact cggtttatcg tctgttctac gatacaatca
     2401 aaggtggtga ctaccgtgcc cgcgaagcaa acgtctatcg tttggctgaa gtgtcaaact
     2461 ctattatcga ccagtgcgta gcacagggtg taccattcgc tcgcgaatat ggtggtctgt
     2521 tggataaccg ctcattcggg ggtgctcagg tatcccgtac gttctatgct cgtggtcaga
     2581 ccggacagca gctgctgttg ggtgcttact ctgcattgag tcgtcagatt ggtttgggaa
     2641 aggtgaagat gtacacacgc catgaaatgc tggatgttgt gaaggttgac ggacgtgctc
     2701 gcggtattat tgcccgtaat ttgattaccg gtaagatcga acgttttgcc gctcacgcag
     2761 tcgttgttgc gacaggtggt tatgtaaata cattcttctt gtctactaac gcgatggcgt
     2821 ctaacggttc tgctgcatgg cagtgctaca agaaaggggc ttactttgct aatccttgta
     2881 tggtgcagat ccacccgact tgtgtgccgg tgaaaggtga cttccagtct aagctgactt
     2941 tgatgtcaga atcactgcgt aacgacggcc gtatctgggt tccgaagaag ctggaagatg
     3001 cgaaggcatt gcaggccgga acaaaaaagg gaaaggatat tcctgaagca gatcgcgact
     3061 actatctgga acgtcgttat ccggcattcg gtaacttggt tcctcgtgac gtggcttcac
     3121 gtgccgctaa agaacgttgt gatgccggtt tcggtgtaaa tagcacgggc ttggctgtat
     3181 tcctggattt ctccgatgct atcaaccgtc tgggtaagga agtggttaaa cagaaatatg
     3241 gtaacctgtt cgatatgtac gaagagatca cgaacgatga tccgtacgaa actccgatga
     3301 tgatttatcc tgcattgcac tactcaatgg gtggtttgtg ggtagactat gaattgatga
     3361 cttctattcc ggggctgttc gcaattggtg aagccaactt ctctgaccac ggcgctaacc
     3421 gtctgggtgc ttctgctttg atgcagggat tggccgatgg ttacttcgta ttgccttaca
     3481 cgatccagaa ctatctgtct gaccagatcc aggttccgcg ctttagcact gacctgcctg
     3541 aatttgtgga agcagaaaag gctattaacg cccgtatcgc gaagttgatg aacgtgaagg
     3601 gtaaagaaac agtcgattct atccaccgta agctgggaca tatcatgtgg gaacacgtcg
     3661 gtatggcacg cgacgcggaa ggcttgaaag aagctatcca aatgttgaaa gacctgaaga
     3721 aggaattctg gagcaatgta ttcattccgg gtgaggccaa tagcttgaac gtggaattgg
     3781 acaaggcatt gcgtttggct gactttatcg aaatcggtgc gttgatggca cacgatgcgt
     3841 tagaccgtgc agaatcttgt ggtggtcact tccgtacgga acatcagacc gaagaaggcg
     3901 aagctatgcg tcatgacgat aagttcatgt acgtctcttg ttgggaatac cagggtgaag
     3961 acaaagaccc ggttatgctg aaggaagatt tgaactatca gttcgttgtt cctcaaacac
     4021 gtaactacaa gaagtaataa tcatcaatca caaaaattag aatcatggat aaagatataa
     4081 aggtaacact taaagtttgg cgtcagaaag gtccgaaaga taaaggacag tttgagactt
     4141 accaaatcga caaaatcaat cagagtgttt ctttcttgga aatgttagac attttgaatg
     4201 aacgtttggt tagcgaaggc aaagaaccta tcgtattcga ccacgactgt cgtgaaggta
     4261 tctgcggtat gtgttcattg tatgtaaacg gacatccgca cggaccggca acaggtgcaa
     4321 caacctgtca gctctatatg cgccgtttca atgatggtga gacgattacg atcgagccgt
     4381 ggcgttctgc tggtttcccg gtaatccgcg acttgatggt agaccgttat gcttatgata
     4441 agattatcca ggcaggtggt ttcgtttctg taaacacagg tggggttcct gatgctaatg
     4501 caattcctat ttctaaggct gatgcggatt tggctatgga tgctgctgct tgtatcggct
     4561 gcggtgcttg tgctgctgct tgtaagaacg gttcagctat gctgttcgtc tctgcaaagg
     4621 ttagccagct ggctcttttg cctcagggta aggtggaagc tgctcgtcgt gcaaaagcaa
     4681 tggttgctaa gatggatgaa ctgggctttg gtaactgtac gaacactcgc gcttgcgaaa
     4741 tggaatgtcc gaagaacatc tccgttagca acatcgctcg cttgaaccgc gagttcatct
     4801 ctgctaagtt acaagactaa tacattatat atgtatgtat atggaaaagc ccgtcgccaa
     4861 tggcaacggg ctttctttat gttcgttcaa acccacaaaa aagccgcact ccctataata
     4921 aaagtggatg cggctttttt gttgctttcc agtgaaacag tctctcgatt ccctctctgc
     4981 aaagactttg ttaaccttag atctaaaata ctatgaaaaa aactcactgc aaatataaag
     5041 tatatttact gaatacgcaa gagtttgtaa ttacatttta ttgcaaattt gctacttttt
     5101 gttttaaaat tgacactgtg tgcggattca cactgttatt atatcaacaa tcgatcgatt
     5161 ctgacacttg agagtcgctt tgaaatccgt atcctgtatg aaatttgtcg gggatggaat
     5221 ccagaatgtc gaataatgct tccactgttt ccgcacgtag catggcgacg cgtgtctgct
     5281 tgaagtctgc aataccttta aacagcggag ttgcagccaa atggcggcga atgtggagaa
     5341 ttccccggcg ctcatccaaa cgttccacgc tttgttccac ctgctttttc agtatgtcca
     5401 gataccatga aaaagattcg gcaggcaatg tctcgcctgt atccagataa tgcctcactt
     5461 ctctgaaaat ccaggggcgg cctatgctgc cccggccaat cataacggca tccacgccat
     5521 attgttcgaa acgttgtttg cagatttcgg cggaagtcac atcgccattg ccgatgatgg
     5581 gaatttgtat acggggattg ttttttactt caccgatcag tgtccagtct gcctctcctg
     5641 tgtacatctg tgcccgggta cgtccgtgga tggaaagggc tgcgataccg caatcctgta
     5701 gctgttcggc caagtctacg atgatccggt tgtcggcatc ccagcccaag cgggttttta
     5761 cggtgacagg gatgttcacc gctttgacga cttcacgggt gatgtccagc atcagtggaa
     5821 tattgcgcag catgccggcg cctgctcctt tgcctgccac tcgtttgaca gggcaaccga
     5881 aattgatatc gagaatgtcc ggatgagcgg cttcgcaaat ttgcgcggct tcgaccattg
     5941 tcggaacatc acggccatat atttgtatgg cgaccggacg ttcttcatcc gccacattca
     6001 gcttttgctg tgttttattt acactgcgga ttagggcgtc tgctgaaacg aattcggtat
     6061 aaaccatatc ggcaccaaaa cgtttgcaca tcaaccggaa agaaatatct gtaacgtctt
     6121 ccatcggagc taagaagacg gggcgttcgc ctaaatctat tgtacctatt ttcatattta
     6181 tattatcaat gacggggaca aaggtactga tttcctgcta aaaacaggga taaaaggata
     6241 tctactaaaa aatatagtaa aataactata tgatatagtt gtgttactaa ataatatagt
     6301 tgtatttgtg cattcctcta acaaaaaacg gattatggtt agattaacat caaaagaaga
     6361 agaaatattg ggctactttt gggcgaaagg ccccctgttc gttcgcgaac tactcgactt
     6421 acaggaagaa tctaagccgc attataacac cttgtccacg attgtccgct cattggaaga
     6481 aaaaggatat atcggataca aggtatacgg taatacgcac caatactatg cactggtatc
     6541 ggaagacgaa taccggcgta attccttgaa acaggtgatc agcaaatatt atgacaactc
     6601 gtacacccgt gtcgtttcga cgctgataga agaagaggtg ctcacgatcg acgagttaca
     6661 gaagctgatc cagcagataa aaaacaaata aaaaaccaac gcttatggac gcttttcttc
     6721 tatacatatt aaaatctggt atttgcctga cagtctttta tgtctgtttc aaggcattat
     6781 tcagtaacga cacgtttttc cggttcaacc gctggatatt actggtaggg acaggagttt
     6841 gcatgttgct gccactttgc cggatccaaa cagcccggcc ttttcctctt agccggccag
     6901 tcagccaact ggagatagtt ttctatgaag aagagatgaa agcgtttcct gttccggaaa
     6961 gcaaagaaga aattacgatt ccgacagagc agagaaatat atctgttccc tggacgggaa
     7021 ttatcgggat tgcttttcta acaggcagtg gtatctgcct gaccacaacg attctgtcat
     7081 tcggaaaaat gtatcaacta acaagaaaaa acaggaaact aaaacagggg aaatacacgt
     7141 taatcctgac tcccgatccc gtatcccctt tcagttgggg acgttatata ttcctttcgg
     7201 aaaacgatta ccggaaccat ccgaacgaaa tcctcatgca cgaaaaaatg cacctccgct
     7261 ataaccattc ggtcgatctg atctatatga aacgattctt cttctgcaat ggtttaatcc
     7321 tgccgtatgg ttattaaaaa gggaattacg gggcatacac gaataccagg cggataaagg
     7381 cgtactcagt caaggcatcg atgcaacaaa atatcaacta ttactcgtga aaaaagctgt
     7441 cggctccagc ctctacactc ttgccaacag cttcaatcac agtaaaatta aaaaacgtat
     7501 tactatgatg ttaaaaaaga aatcaaacaa ttgggcccgg ttgaagcttg cgctcctggt
     7561 cccggtaggc ttcgcggcct taagtgcatt cgcccgtccg gaaacaagtc cgccgccggc
     7621 agcgacaatg accgacaaca ttcatctatc gattaacaaa agtacggtaa atcaggaaac
     7681 gatgcaacag gatcatgcag ttttcctcac ctacaaagaa tcgggttcgg aggatctgaa
     7741 cagtattgta tgcaaaactc tggacagaat cagaacacga gtagcggagg gacaattcaa
     7801 gaacgccctg gaagttactg ttaatccggc cttcgacgat atcccggctt cttatctgga
     7861 aacagtaaaa gatgttttgg aagaaagaga tattaaatgc aagatcgaca tgactgttcc
     7921 gaatactatc atggatgatg ttgccaaacc ttaccgcaaa tatgacgatg tggtttatct
     7981 gattcagaat aaaaagattg tcgcagcact aagcatcagt aagtttagtg caaaccagaa
     8041 tgatccgagg ctggataaga tatccaaatc agcttcctta attctccaac ctgaaaatcc
     8101 gaaagtatcc agacaagaaa tggagaaatt aaaaaacttg ttggacaaaa aaggattgac
     8161 aagcgaaatc aacatgaata ttttcaagat cggagatgct gcggctccac ctcccccacc
     8221 tcctgccgga caggttattt tcagttaccg ggacgggcag ccggaccaac agttcgtttt
     8281 atacgatcgc catgccaaac cgggagccaa tctcggacaa cgcatagaca agatttacaa
     8341 ggacaatatt acgaaagtaa gtataaagat taacaaaagt actcccaaag acctgttgga
     8401 aacggttaag caagaactga aaaagaaaat caattaccct gtccaatacg agatcctgca
     8461 attcgtcgat taaaatcaga aacacggatt atctatttat catcctctcc gtttacaaaa
     8521 cctgctccag ggggtaaacg gagaggaata ttattatctt tactccttca aaagaaggat
     8581 tcagatgata cacaatgtaa agatactctt tttcatttgc tttttcaccg cctgttcttc
     8641 taccgaacaa aaagagattg tcaccgccgg agagctcctt cgacaggctg ctttctatgg
     8701 ggaaagattg caatttcttc cggcattgga aacctatcaa caggcaatca aattggcgga
     8761 gaaggagaaa gacagcaccg tcttttccct tgcctacctg gaaatgggaa aaatctatcg
     8821 gtatcaatct ttaaaacaaa aggcactaca aagtgagaaa aaagcattaa gctatatcaa
     8881 aagtcctgcc tgcgattcgc tacggctgga actttaccgg gaaatagggg atatgtatac
     8941 cttgtccgga caagcagaca gtgcctttca ctattatgaa atggctggat gtcggataaa
     9001 acaggcaaag atattgcaac agaatggaag caataaagag gctgaaactt tattaaaaac
     9061 ggagttggaa caaacgattt tcccgaaaga gaaagcagaa gtatgtctgg ctttggctga
     9121 tttgcagatt actttgggaa aattggacga agccgaaaag agtttaagtc aggtcccccc
     9181 ttcccacccg catctgtatg ctgccctgtc ccgcatcgcc caaagccgtg gagacagcct
     9241 gcaagctgat ttctaccaca aaagctacct ccatcactta tccgtcctgc gacaggaaaa
     9301 agaacaaaat caaattaccc aactccttcg tacctcggaa cagaaagaat gggaaaaacg
     9361 tttaaccgat agccaaaagg cacaaaaaga acaaatatat gtctgggtca cgctacttgt
     9421 ctcttgcagt accggaatct ggggatattc ccgctaccgg cagaaaagaa atgtcgtttc
     9481 cctgtccgaa acagatttct tttcttcaga aatctacctg cgcttccacc gaaaagaaga
     9541 atggaaaccg gttcccaaag actgggaaga attgttgcaa gctttcaacc ggacctatcc
     9601 ggatttccgg gaacggctga aaaggaaaat accaaagttg agcgaacagg aatggcgcat
     9661 gtgctgcctg atcaaaatgg aagttccccc ttctactgcc gccatgctcc tttgctgcac
     9721 gaaccaggcg atttcgatgc gccgcgtacg cctgtaccag aaaatcacag gtgaaaaggg
     9781 cactcctgag ctgtgtgatt cctttattcg tgatttttaa gcagatgtga actgatgtga
     9841 aaccggggaa atagccgtat cttctacttt tgtctaaaaa aagcgtatga aaaagatgtt
     9901 gttcgggctt atgacagcca ttgccacttt taccggatgc gaatccaaac aacccgccgg
     9961 agaactcccc cggatcgatc tgacagcaac aagttttgct ttcgatcaag tagagattgc
    10021 agacgaaatc gaatccatcg aatatgttcc gttggaacta acggatgaat ccctgatcgc
    10081 agacgtattg gatctgtgtg tttcagacga atatatcttc gtctattcta cccgtcagga
    10141 cggtgtcttg cagttcgacc ggaaagggaa gtacttgcgc tgcatcgcta aaacaggaaa
    10201 cgggccggga gaaaccggac agatcatttc gctaaccgta gacgaagaga accgcctctt
    10261 ctgtgtcagc gaatacttct ccacctcttt ctactccttt gatggagaat ttatcaaaaa
    10321 gatagagaat ccgcgccctt actcgtacca attctctgtt ggcccgaata cgatggcgga
    10381 attagggagg atgtatgttc ccatgaacac gccgggcatg ttcagtctcg gagtctttaa
    10441 ttggggcaca gacgatacga tcgcattccg gcatacgatc ggggatatgg atctgatgcc
    10501 gttggaagaa acgagcctga aaggttggat attcagcggc agtaaggacg gcatactatg
    10561 ctattcggaa gggatagaca cggtctggga tgtaaatgca agaaatatcg ctccggcttt
    10621 tcttatcaac acgggatatt ctgtcgagga agaaaaagaa atgcgctctt ccaaaaccgg
    10681 taatgaggcg gtagacggga aatatagcgt cttcagcttc tttgagacac cccggcatta
    10741 cttcgttaaa tgtttcgaag gttccaacca atccaaattc tatttgtacg gcttggataa
    10801 ggctaccggt gagttgaaac gtgaaacttc tccgcttaat gcccaggaat tattcaaaaa
    10861 caactggacg ctggcaggaa taggcttccg aaatacgaaa gacaacggtc ttcctatctg
    10921 gccttacctg tcttatcccg gcaaaaaaca aatggtacag tttaatacag ccgtggaaat
    10981 cgaatatctc aaagagaaat atcctgatct caagaagcat ctggtcctgc aacagataac
    11041 ggaagattca aatccgctca tcacgattta tcatttgcgc tgatcttctc ggatattatt
    11101 cctacctttg cgaacgaacc agtaaatgta taagaacttg aacgagaaag attttgaaat
    11161 aatggcgcct gtcggttcgt acgaatcact gatggcggct atccaagggg gagccgattc
    11221 tatctatttc ggtatcgaag gattgaatat gcgttcgcgc tcttccaata actttacgac
    11281 agacgatttg cgcaagatcg ttgcgctttg tcgtgagcac ggtattaaga gctatttgac
    11341 cgtcaatacg gttatttatg gggaagacct gcctctgatg cgcgagatta tcgatgcggc
    11401 gaaggaggcg gaagtttcag cgatcattgc ggccgatgtg gcagctatga actatgccaa
    11461 cagcatcgga caggaggtgc atctttccac acagctcaac atttccaatg cggaagcact
    11521 gaaattctat gcccgttttg ctgatgttgt cgtcttggcg cgtgagctga atttgaaaca
    11581 ggtgcatgaa atctatcggc agatcgtcga ccagcagatt acgggaccga aaggagaact
    11641 gatccgtatc gaaatgtttg cccacggagc tctctgtatg gccgtttccg gtaaatgtta
    11701 cctgagcctg cacgaaatga acgcttccgc caaccgggga gcttgcatgc agatttgtcg
    11761 gcgtgcttat tcggtaaaag ataaagacag caatatcgaa ctggatatcg aaaaccagta
    11821 tattatgtcg cctaaagacc ttaagacaat tcatttcatg aataagatga tggatgcagg
    11881 tgtacgggta ttcaagatcg aaggacgtgc ccgcggtccc gaatatgtcc gcctggtgac
    11941 cgaatgctat aaggaagctg tgcgtgccta ttgcaatggc acgttcgatg aaaagaaagt
    12001 tgccgcttgg gacgaacgcc tgcgcagtgt gttcaaccga ggattctggg atggctatta
    12061 tttggggcaa cggttgggtg agtggagtag caaatatggc tccggcgcga ctaagaagaa
    12121 agtgtatgtt gccaaaggaa tcaaatattt cgacaagatc ggcgtggcgg agttcgaaat
    12181 ggaatccggt aacctgaaag tgggtgatga gatcctgatt accggaccga caacgggtgc
    12241 ggttatgcag acgatagaag aaatccgtgt ggacttgaag ccggtggacg agaccgttaa
    12301 aggtgaacgg ttctctctca aggtgaacga gaagattcgg ccgtctgacc gattgtataa
    12361 aatggaaaag gttcaacttg aaaaggtatt tgaataatga aagagtatat ttttaaactg
    12421 acagacaagg tccgtgacta cgaatgcgac ctgcaaggag tggtcaacaa ctccaattat
    12481 cagcattata tggaacatac tcggcatgaa ttcttggagt cgcttggcga gaacttcgga
    12541 aagatgcacg aaaaaggggt tgacggattt gtatcgcggg tagaaatcca gtataagacc
    12601 tcgctcaaga gcggcgacag ctatatctct tgcctcaatg cctataaaaa aggagtcaag
    12661 ctcgtattcg agcaggatat atatagggct tctgacaatg cattggcgac gaaaggaatc
    12721 gtcgagtcgg ttatcgttga gaacggaaag ttgacacgcg gtgaatattt cgacgaaatg
    12781 ctaaaaagaa tagaacatac atgactgaca aacggattta ccaaatcggc cttactatga
    12841 taaacggcgt gggagatatc ctggcgcgtc atctcctgca ggctttggga gaagcagagg
    12901 ctgtgtttac tgaaaagcaa cagttgttag gaaggatccc tggtatcggc agcaatattg
    12961 ctgccgaaat caaacgcccg gaaatcttgc aacgggcgga aaaagagttg gcttttatcg
    13021 agaaaaacaa tatttcctgt tattatctga ctgatacaga ttatccggtg cgcttgagag
    13081 aatgtccgga tgcccctata cttttctatt ttaagggaaa tactaacctt gatgcgaccc
    13141 gtatcatcag tattgtgggt actcgcaacg cgaccgaata tggtcgggag cttaccgaat
    13201 cccttataaa agacttggca aaagtgatcc cggacttgtt ggtcgtgagt ggattggctt
    13261 acggcatcga tatctgtgct caccggaacg ctttgtacaa ccgacttccg actgttgctg
    13321 tgctggcgca tggcttggat cgtatctatc cttcctgcca tcggaatacg gctgtcgaaa
    13381 tgctggaatc gggcggtctg ttgaccgatt ttcccagcgg tacagaacca gaccgtccaa
    13441 atttcctccg gaggaaccgg attgtcgccg gaatctcgga ttgtacgatc gtggttgaat
    13501 cggcagaaaa aggaggctct ttggtaactg ccgatattgc attctcttat ggccgggatg
    13561 tctatagctt tccagggcgt gtcggtgaca gccattccaa aggatgcaac aatttgatcc
    13621 gacaaaataa agccggcctg atcacttctg cggacgatct gctctccgct ctttgttggg
    13681 atatccaagc tggggctact cccgttcaaa cggagttgtt tttcgccgaa gcggaaacat
    13741 tcacctcgga acaaaatccg gttttagcca ttatgcgaac gcggaatgag attcatatca
    13801 acgagcttgc ctcagtgttg gagataccgg tacatcaact ctctatgcta ttgttcgaac
    13861 tggaaataaa cgggaaggta aaagcgttgc cgggaaatct ctataagctg tcctgaccgg
    13921 ctttttcgta tacgatttgt atgtgggaga agaaacggaa cctctataaa caattaaagg
    13981 ctgtctcacg acaaccccta accaactttg ttaaccttaa atctaatact attatgaaaa
    14041 aaccacattg caaagatact ctcgtcaaga gcgtttgtca agcattttgt tgctaatact
    14101 tgttaatcag atgagcataa atagcaaaaa gattttaatc ggctataaag agtcctttaa
    14161 actgcgttat tttgttaaat cgagtccttg aaacaggtac ggatagtccg tttcgatcac
    14221 gtcgggacga gtgctgatct ctgaccggta accggcggtt ttctctgttt ccgttttcgc
    14281 gcgatcatgt gtcggagcaa cggaaatcat gcacatgact ccgttacggt gcagagcgtc
    14341 atacagtggt tgctgttcag gcttcatctt cgggcctaca taagccatta cctgtttcca
    14401 ggggatgccg gctttttcat aattatcgaa ttcttcccga ttcttacacc agcaagaaaa
    14461 catcgcatcc ggtttccggt cgagataata gcgggcttga ctggcgttat gtaccgtgta
    14521 catgacgtta acaggctttt ctgtttctat aaaatcagcc ataacttcta aaggtacatc
    14581 cttgatatcc aaattcagga ttgttttgcc tttgctccat tccaggcatt cttttaaagt
    14641 tggaattttg aaggctgtca cgttgccgtt tcggtccacc agattgaatt gttgcagttc
    14701 tgcataagtg taatctgaaa cctttccttt cccggtagtt gtccggtcga tggtttcgtc
    14761 gtgcatcaat acgattatcc cgtcttttgt caaacgcgga tctatctcga aaaacgattc
//
