LOCUS       c00330_gnlPro..         5900 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IGIJEBNG_330.
ACCESSION   c00330_gnlPro..
VERSION     c00330_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 20:32:03
            Original ID  :: gnl|Prokka|IGIJEBNG_330
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5900
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5900
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[205:5900]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      206..5900
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..5900
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..5900
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             206..2041
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg330_1"
                     /sec_met_domain="ILVD_EDD (E-value: 8.4e-219, bitscore:
                     715.7, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKNPLRSSYSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSF
                     TQFVPGHVHLHEIGQQVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIAD
                     SVEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTIFVSGGPMEAGNLDGRALDLI
                     DAMIEAADDSISDEQVEKVERSACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTVVAT
                     HANRTRLFKKAAKMIVDNAFKYYRDGDDSVLPRSIATRQAFLNAMSLDIAMGGSTNTVL
                     HLLAVAHEAEVDFTMKDIDMLSRKTPVICKVAPSCSYHVEDVNRAGGIIGIMNELVKAG
                     LVDGSVKRADGLTLNEAIDQYCITSVNVTEEAINIYKSAPAYRFNLVLGSQESYYKELD
                     TDRATGCIRDVEHAYVKDGGLAVLYGNIAQDGCVVKTAGVDESIFRFAGPAKVFDSQDA
                     ACEGILKDKVVSGDVVVITYEGPKGGPGMQEMLYPTSYIKSKHLGKECALITDGRFSGG
                     TSGLSIGHISPEAAAGGAIGLVKDGDIIEINIPERTIHVKVTDEELAKRREAEEARGTK
                     AFTPPFRQRTVSKALKAYAKMVASADKGGVRIVED"
     CDS             2068..3768
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg330_2"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.7e-51, bitscore:
                     162.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LKHILVRHEQGATHAAQGYARVSGKVGVTVVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRRPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVDYEYQKVDYVRSYQPEPDIREERIEAAASLINNAKKPFCLVGQGVILGG
                     AEEELKEFLLKNDIPAGSTVLGLSALPSDFPLNKGMLGMHGNVGPNRKTNKCDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFEPDEKEEYNKVIEKELYPTEGQLKMGEVVRKVSEATDNDAILVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAIGAKLGAPDRTVCFFTGDGGIQMTIQELG
                     TIMQENLNVKIIVLNNNFLGMVRQWQELFFNERYSNTIMKNPDFVAIAKAFGIASRAVD
                     KREDLDEAIAEMLNHDGAYMLVANVETCGMVYPMVPAGGSVTNMILGDK"
     CDS             3781..4335
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg330_3"
                     /sec_met_domain="ALS_ss_C (E-value: 5.6e-19, bitscore:
                     56.7, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKQLYTVIIFSENTVGLLNQITVIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDTIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEDLIRKYNARILEMNEDCVVLEKSGHYDETQALFKELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLSAMEKKLQEKHV"
     CDS             4372..5103
                     /locus_tag="ctg330_4"
                     /transl_table=11
                     /translation="MEKNKVGEFHFVTESYLMDFRGRITIPMIGTYLLHAASCHAADRG
                     FGYNDMTERHTAWVLSRLAIEMTSYPAMSESVTLYTWVDEVGKLFTSRCFELVNGEGKT
                     FGFARSIWAAIDMETRRPTLLDVEGLSAYITDRPCPIEKPGKIAPVENNTSGEPYRVKY
                     SDLDVNGHLNSIKYMEHLLDLFDISLFREKEISRFEIAYQSEGKYGMELTLHNQEVSPG
                     KYNMAICNDGKAISRAAVTWI"
     CDS             5145..5900
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg330_5"
                     /sec_met_domain="IlvN (E-value: 2.5e-49, bitscore: 155.5,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.6e-19, bitscore: 59.1,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVMNFGGVDENVVTREEFPLEKAREVLKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRKGGKTWEKAVADGWVPGETLFDIEEACEKATIIQYLLSDAAQI
                     EVWPRIKKYLTPGKALYFSHGFGITYKERTNIIPPADVDVILVAPKGSGTSLRRMFLQG
                     RGLNSSYAIFQDATGKAWDRVIALGIGVGSGYLFETTFKKEVYSDLTGERGTLMGAIQG
                     LLLAQYETLRENGHEPSEAFNETVEELTQS"
ORIGIN
        1 ttctacattt gcagcgtcaa acaaacaaag acaataagaa aagatgatga acaacgtatt
       61 gcatattatt ctcgtggtgg tccttctagt cattagtagg taaggagaaa ggtgtgtaag
      121 aagttgtgaa gtcgtaaaag atatttctta agcctttctc catatagaga agggcttttt
      181 tattgactaa aagataaaaa cagatatgat gaagaatccg ttaagaagct cctatagcac
      241 agaaggcaga cgtatggccg gagcccgtgc attatggcgt gccaacggca tgaaagaaga
      301 acagttcggt aaaccgatca ttgccattgt gaattcattt acccagtttg taccgggcca
      361 tgtgcatcta cacgagatcg gacagcaggt aaaagcggaa atcgaaaagc tcggttgctt
      421 tgccgcagaa tttaatacga tcgctattga tgacggtatt gctatgggac acgacggaat
      481 gctttattct ctgccttccc gcgacatcat tgctgacagt gtggaatata tggtgaatgc
      541 gcataaggct gatgcaatgg tttgtatcag taactgcgac aagattactc cgggtatgct
      601 gatggccagt atgcgtctga atattccgac aatctttgta tccggcggtc cgatggaagc
      661 cggtaatctg gacggacgtg cactcgattt gatcgacgcc atgattgaag cggctgacga
      721 ttctatcagc gatgaacaag tagaaaaggt ggaacgttcc gcttgcccga cctgcggttg
      781 ctgttctggt atgttcacgg ctaactctat gaactgtctg aacgaagcga ttggattggc
      841 tcttcccggc aacggaacag ttgttgcaac acatgccaac cgtacccgcc tgttcaaaaa
      901 agcggcgaag atgattgttg ataatgcctt taaatattat cgtgacggcg atgattccgt
      961 attgcctcgc agtattgcca cccggcaggc ctttctgaat gctatgtcgc tggatattgc
     1021 catgggggga tcgacgaata cagtccttca cctgttggcc gtggctcatg aagcggaagt
     1081 cgattttaca atgaaagaca tcgatatgct ttcacgcaaa acaccggtta tctgtaaagt
     1141 ggctccgagt tgttcttatc acgtggaaga tgtgaaccgt gccggaggta tcatcggtat
     1201 tatgaatgag ctggtaaaag ccggtctggt ggacggctcc gtgaaacgtg cggatggtct
     1261 gactttgaat gaggctatcg accaatactg cattacctct gtaaatgtaa cggaagaagc
     1321 aatcaatatt tataaaagtg ctccggccta ccgtttcaac ctggtgctcg gatcgcagga
     1381 aagttattat aaagaactgg ataccgaccg tgcaaccgga tgtatccgcg atgtggaaca
     1441 tgcttatgtg aaagacggcg gtctggctgt tctgtatgga aatattgcac aggacggttg
     1501 tgtggttaaa acagccgggg tagatgaaag tatcttccgt tttgccggcc ctgccaaagt
     1561 attcgattcg caggatgccg cttgcgaagg tatcctgaaa gataaagtcg tctccggcga
     1621 tgtcgtcgtt atcacctatg aaggtcctaa gggtggtccg ggtatgcagg aaatgttgta
     1681 tcctacttct tatataaaga gtaaacacct gggtaaagaa tgtgcgctaa tcacagacgg
     1741 acgcttcagc ggtggaacat cgggtttgtc aatcggacat atttctcccg aagcggctgc
     1801 aggcggagcg attggcttag tgaaagacgg cgatattatc gaaattaata ttcccgaaag
     1861 aaccatacat gtaaaggtga cagacgaaga actggccaaa cgccgtgaag cggaagaagc
     1921 tcgcggaaca aaagccttta cacctccttt ccgccaacgt acggtatcga aagcactgaa
     1981 agcatatgca aagatggttg cttcggccga taagggcggt gtacgaatag tagaagatta
     2041 ataaacacca aatactatat tttagagatg gacaaacaaa agataaccgg ttcggaagct
     2101 ttgctgaaag cgctgatcgc tgaaggagta gatactatct tcggttatcc gggtgggcag
     2161 gcgataccaa tttacgatag tttatacgat tacagagatc agttaaaaca tattctggtg
     2221 cgccacgaac aaggtgcaac acatgctgca cagggatatg cccgtgtttc cggaaaagtg
     2281 ggagtaacgg tggttacttc gggtcccggg gcaaccaata ccatcactgg tattgccgat
     2341 gcgctgatgg acagtacacc gatggtggtg attgccggcc aggttccgtc tccgctgctt
     2401 ggaacagatg ctttccagga agttgatgta attggtatca cacaaccgat taccaaatgg
     2461 gcttaccaga tacgccgccc ggaagaaatt gcttgggccg tttcccgtgc tttctatatc
     2521 gcatcgaccg gtcgcccggg acctgtggta ctggatttgg cgaaagatgc acaggtgggt
     2581 ttggtagatt atgagtatca gaaagtggat tatgttcgta gttaccagcc tgaaccggat
     2641 atcagggagg aacgtatcga ggcggctgct tcattgataa ataatgccaa aaagccattc
     2701 tgtctggtag ggcagggggt tatcctggga ggagctgaag aagaactgaa agaattcttg
     2761 ttgaaaaacg atataccagc cggttctacc gtattgggct tgtctgcatt accttcggac
     2821 ttcccattaa ataaaggtat gttggggatg catggaaatg tcggaccgaa ccgcaagaca
     2881 aacaaatgtg acgtgctgat tgctatcggt atgcgtttcg atgaccgtgt aaccggcgac
     2941 ctgaagactt atgccaagca ggcaaagatt atccacctgg atatcgacaa ttcggagatc
     3001 ggaaagaatg tgccggtcga cgtgaaagtg ctgggaaatg ccaagcatac gattccgatg
     3061 attacggctt tactggaaga acggaagcgt ccggaatgga atgctgaatt cgaaccggat
     3121 gaaaaagagg aatataataa ggtaatagaa aaagaactct atcctaccga aggccaacta
     3181 aaaatgggcg aagtagtccg taaggtttcc gaagcaaccg ataatgatgc gattctggtt
     3241 acggatgtag gtcagaacca gatgatgggt gttcgctatt tcaaatataa acaaacacgc
     3301 agcgtagtta cttcaggagg tttgggaacg atgggctttg gccttcccgc cgccattgga
     3361 gcgaagctgg gagcgcctga ccgtacggtc tgtttcttta ccggcgacgg tggtatccag
     3421 atgactatcc aggagttggg aactatcatg caggaaaatc tgaatgtaaa gatcatcgtt
     3481 cttaacaaca atttcctggg aatggtacgc cagtggcagg agctgttctt caacgaacgg
     3541 tattcgaata ccatcatgaa gaatccggat tttgtagcga tagccaaggc ttttggtatt
     3601 gcttcccgtg cggtagataa acgggaagac ttggatgagg cgattgctga aatgttgaat
     3661 cacgatggtg cctatatgtt ggttgccaat gtggaaactt gtggtatggt atatccgatg
     3721 gttccggccg gaggaagcgt gacaaacatg attttgggtg ataagtaagg aggagaaact
     3781 atgaatacaa aacaattata taccgttatt atcttttcgg aaaacactgt tggtcttctg
     3841 aatcagataa ctgttatctt tacgcgccgg caactgaaca ttgagacgct ttctgtttct
     3901 ccctctgcta taaagggaat acataagttt acaattacta cctttgccga cgaggatacg
     3961 atcgacaagg tcgtaaaaca gatcgacaag cgtgtggata tcctgaaagc ctattataat
     4021 acggatgaag acctggttta ccaggaaatt gctctttata aactgagtac cgaactcttt
     4081 atcaagatgg ggacggttga ggatctgatc cgtaagtaca atgcccgtat ccttgaaatg
     4141 aatgaggatt gtgtggtgtt ggaaaagagt ggtcattatg atgagacaca ggctttgttt
     4201 aaagaattga gtgagacgat cggtgtcctg caatttatcc gttccggacg cgttgctata
     4261 acgaagagta aggtagaacg tctgagcgac atgttatctg caatggaaaa gaagttgcag
     4321 gaaaaacatg tctgagaaca acaaggaaac attttgtaaa taaagtaaat tatggagaag
     4381 aacaaagtag gagaatttca tttcgtaaca gagtcttatc tgatggactt ccggggacgt
     4441 attacaatcc ctatgatcgg aacttatttg ttgcatgctg cttcttgcca tgccgccgac
     4501 cgtggattcg gatataacga tatgaccgaa aggcataccg cctgggttct ttcccgtctg
     4561 gctatcgaga tgacttctta tcctgccatg tctgaatccg taactttata tacctgggtg
     4621 gatgaggtcg gtaagttgtt taccagccgt tgctttgaac tggtgaacgg tgaaggcaag
     4681 acctttggct ttgcccgctc tatctgggcg gctatcgata tggaaacccg ccgcccgacc
     4741 ttgctcgatg tggagggcct gagtgcttat atcaccgacc gtccctgtcc gattgaaaaa
     4801 ccgggtaaaa ttgctccggt ggaaaacaac acttccggcg aaccttaccg tgtgaagtac
     4861 agtgacctgg acgtaaacgg ccacctgaac agtatcaaat acatggaaca cctgctcgac
     4921 ttgttcgata tcagcctgtt ccgagaaaaa gagataagcc gtttcgaaat agcttatcag
     4981 tccgaaggaa agtatgggat ggagctgact ctccataacc aggaagtatc ccccggtaaa
     5041 tataatatgg caatctgtaa cgacggcaaa gccatcagcc gcgctgccgt tacctggatc
     5101 tgaaaaacaa attattttat atacatttta atagtaaaaa gaaaatggca gtaatgaatt
     5161 ttggcggcgt tgacgaaaac gtagtaaccc gcgaagaatt tccgttggaa aaggcaagag
     5221 aagtattgaa agacgaaaca atcgctgtaa taggttacgg cgtacaaggt cctggccaga
     5281 gcctgaacct gcgcgacaat ggttttaacg taattgtagg acaacgtaaa ggtggtaaga
     5341 cctgggaaaa ggccgttgct gacggttggg taccgggcga aacactgttc gatatcgaag
     5401 aagcatgcga aaaagcaact atcatccagt atctgctttc agatgctgct cagattgaag
     5461 tttggccgcg catcaaaaaa tacctgactc cgggtaaggc tttgtatttc tctcacggat
     5521 tcggtatcac ttacaaagaa cgtacaaaca tcatccctcc tgctgatgta gacgtaatcc
     5581 tggttgctcc gaaaggttca ggtacttcac tgcgccgtat gttcttgcag ggtcgtggtc
     5641 tgaactcaag ctacgcaatc ttccaggatg caacaggcaa agcatgggat cgcgtgattg
     5701 cactgggtat cggtgttggt tctggttact tgtttgaaac aacattcaag aaagaagttt
     5761 attctgacct gaccggcgaa cgtggtactt tgatgggagc tatccaggga ttactgttgg
     5821 ctcagtacga aactttgcgt gaaaacggtc acgaaccttc tgaagcattc aatgaaacag
     5881 tagaagaact gactcagtca
//
