LOCUS       c00137_gnlPro..        16446 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MODHNEPK_137.
ACCESSION   c00137_gnlPro..
VERSION     c00137_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 00:02:06
            Original ID  :: gnl|Prokka|MODHNEPK_137
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16446
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16446
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3761:6446]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3762..6446
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..16446
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16446
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(2..88)
                     /locus_tag="ctg137_1"
                     /transl_table=11
                     /translation="MKPAKFALFKTLTVFFQNIEFRKTQSRVN"
     CDS             complement(396..764)
                     /locus_tag="ctg137_2"
                     /transl_table=11
                     /translation="MATIYRKSDLLLIVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXPIYY"
     CDS             complement(828..1607)
                     /locus_tag="ctg137_3"
                     /transl_table=11
                     /translation="LEGEFIGQSTHEYSVIYMRHIGKDRFAAISFPFQPFNGGGFGLGL
                     FSRKGDTIAIKNDFYSFLLPHEKSGFTTSIAPAYSDAQNSVLFKTGSNYTVFSISADRI
                     SAACVLDLKNSDAEVIRSLDVTDMSNLRIEKKAPKDIFVQDMIEFPEHYYFRLLYNQGY
                     YIASVDKKTGKTLVEKCEMPGSIYELADANLQHGMQGTRSYRNFPVWGRVIKDELVQVV
                     TPYELNLYKSLRSITIPQELDLKGEEGNPVFVFYSLI"
     CDS             complement(2161..3576)
                     /locus_tag="ctg137_4"
                     /transl_table=11
                     /translation="MNNLYTFAYMRKDLNGPRHFSIGIKFTILLFTIAILVLVLFSYRS
                     DKHGNLFWQVEKLIPHHPDSALVLLEKVTDINGLSLREKARYCLLWTESRDEAGLRHTS
                     DSIISIATDYYRTTRGCYWPPKAWFYRGKVYEDMDQPSLALECYLRALEYEGGNWDYEF
                     WGRLYNQIGRLYAEQELYGKAMSFLRKASAQYQLLNDTAGQGRILEEVKKYEALRDSIG
                     SLSARESIYQITSRYDVRPVREDLYRKELMLSQRGQERYLYAFIIGIILFICFLLYRRW
                     RNTQENALRREEALRRSIASQQQRMREEKEENERQIALLEKRITKIKEEKDQELMLVSL
                     QLEKQRLEICNESIHNKESKHLLSVAILRKSEVYEKFHDRDAGKIVFEDWELLEVLLNK
                     AYDDFTLRLKKLYPAISDTELKVCMLTKIGVPANQITRVLKYNSSVLRPRLFRKIFKKE
                     GSTETFVEFISSF"
     CDS             3762..4454
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg137_5"
                     /sec_met_domain="SucD_FumR (E-value: 6.3e-74, bitscore:
                     238.5, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLVLFLLFHLSMNVAAVFSGEAYNMV
                     CSLLGSNWYAVAATLVLAAGVVIHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGLIVILFMLLHFSQFWYKMMFAELIGHHEVALGSAMVSPQDGAAFINYYFQGNAM
                     ITVLYLIWYVALWFHLTHGFWSAIQTIGWNNTIWMNRWECISKIVATVICGLFAIITII
                     FFLNGVGA"
     CDS             4578..6446
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 197.3; E-value:
                     1.5e-60)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg137_6"
                     /sec_met_domain="FAD_binding_2 (E-value: 6.2e-61, bitscore:
                     197.3, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.7e-38,
                     bitscore: 122.3, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LVNPANKRRLDVIVVGTGLAGASAAASLAEMGFNVLNFCIQDSPR
                     RAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKGGDYRAREANVYRLAEVSNSIIDQCV
                     AQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQTGQQLLLGAYSALSRQIGLGKVKMYT
                     RHEMLDVVKVDGRARGIIARNLITGKIERYAAHAVVVATGGYVNTFFLSTNAMASNGSA
                     AWQCYKKGAYFANPCMVQIHPTCVPVHGDYQSKLTLMSESLRNDGRIWVPKKLEDAKAL
                     QAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDVASRAAKERCDAGFGVNNTGLAVFLD
                     FSDAINRLGKEVVKQKYGNLFDMYEEITNDDPYETPMMIYPALHYSMGGLWVDYELMTS
                     IPGLFAIGEANFSDHGANRLGASALMQGLADGYFVLPYTIQNYLSDQIQVPRFSTDLPE
                     FNEAEKNIQARINKLMSIKGKESVDSIHKRLGHIMWEHIGMARNAESLKEAIQMLKDLK
                     KEFWSNVFIPGNADDLNVELEKALRLADFIEIGTLMAHDALDRAESCGGHFREEHQTEE
                     GEALRHDDKFMYVSCWEYQGEDKDPVMLKEDLNYEFVVPQTRNYKK"
     CDS             6744..7226
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg137_7"
                     /sec_met_domain="Fer4 (E-value: 2.1e-07, bitscore: 21.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 2.1e-12, bitscore: 38.1,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.1e-06, bitscore: 18.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRFNDGETITIEPWRSAGFPVIRDLMVDRYAYDKIIQAGGFTSV
                     NTGGVPDANAIPIPKPDAEMAMDAAACIGCGACAAACKNGSAMLFVSAKVSQLALLPQG
                     KVEAARRAKAMVAKMDELGFGNCTNTRACEMECPKNISVSNIARLNREFICAKLQD"
     CDS             7288..7797
                     /locus_tag="ctg137_8"
                     /transl_table=11
                     /translation="LLYVEKHNLALQILTGIEKSVYLHRGFXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQALI
                     VYRPTF"
     CDS             7989..9200
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg137_9"
                     /sec_met_domain="Radical_SAM (E-value: 2.3e-16, bitscore:
                     51.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKRTTSSFRAMSTERKLESIFLFVTGRCNAKCAMCFYAQEMDK
                     KQPDLTFDEIKKISETAGQFNRLWISGGEPTLREDLPEILELFYKNNHIKDVNIPTNGL
                     KPDRIVEWVKRFRQNCPDCNINVSLSLDGFGTTHDTQRGVPGNFYKALETLRKIQENFG
                     DDGKVLKNIATVITKYNIDQVEDFMTWVYGRFRTSTHTIEAARGMTRDDGVKILTESTL
                     RKIQDDISPIYSAYADRMVADTTGLRKPITHFFYLGLIRTLYNVRASNIDHPTPWGMDC
                     TAGETTLVIDYDGRFRACELREPLGNIKEYGCDISKVMNSEAMKQEIAAIGHGYKANCW
                     CTHGCWITSSVIFNPRKMIRSVYKGYRETKRLNHPLAINEQKLQTMEAKYHLDIERLRQ
                     LNIR"
     CDS             9234..10466
                     /locus_tag="ctg137_10"
                     /transl_table=11
                     /translation="MKILLVTRGSQGDVLPYLAIAAELERRGHEVTINLPQIFEETVKP
                     YGFKYVLQQFDDIGGMIDSAAQNSHKFRPFLKWMRNVIDKQFDQLIPLLKEHDILVSTN
                     SEFAVASIAEYCKKPLIRTAYAPFLPGKKIPPAVLPFPKPNPIITPAILWKLMNRMTNF
                     MVKDTINKNRAKYGLAPIRNFGYHAGERSYNYLLFSQHLGNVDPDWTFEWSIGGYCFND
                     TFQYDEKAYEEMISFVDSAQSPIIFFTLGSCSSKDGNRFSKALVDICKKHDYRLIIGSG
                     WAKTGITLQADKHLFLMKQPVPHNLIFPHCDGVIHHGGCGTTHSVGRAGKPQLITPLII
                     DQPYWSYRIHQLGLGPEGVKIAKASEQEIERKVCDLVTNPLYKKNAAHIGEMIQKEGGI
                     KNICDSIERFQ"
     CDS             complement(10949..14086)
                     /locus_tag="ctg137_11"
                     /transl_table=11
                     /translation="MIRNIISLKVIILYFGLILCLIAGMPTPAYGSSSYPVKEESYVLV
                     INSYMDSERWSGNLLNMISKFATPEEYTLRIDHMNVILVDTPEKLKEKQKLFFETYKEK
                     PGGIIYLGVNGWAFMRDKIREEWGDIPSLVCSETGEMAEDECYFNQRHSSDRVIPLQEA
                     VKGYNATGLVIPYYVKGSIDLVKELIPGLRRLIFISDRRYVSTWLRDEMEKHMETSFPE
                     GKVDFYTEGSCSMDSLMAVLSEKDPHRATAVMYYSWITEKPFLNHSLLYSTLYQGINGI
                     SRHPVFSLYDMGVEEGYTIGGYYNSTKTIETALIPLLQQVYNGEDMGKIPVSTVDDPHK
                     YLNYVSLMSAMSNEDNFPHDAIYLNAPPSFLEKYWMPLLGFLIFFLVVVFLAWHYVYRS
                     KQKMKEVELRLLSRYRDLFNNMPLPYIRQRLIREGTQIDVQVLDVNHAFEEKIAPKDFV
                     VNKHGKEIANLIGGSYPLLLSAVPTVLESGKSFTCEYYFEPTGLYYTVIIMPTSEENVV
                     DAFFIDITDIHNFQTHLKAMNHKLAMALEAADLLPWRYNLAEGKIIYESKVHPGDNIET
                     AEVHTHEVSLEEYFSKIHPSFRACVEKAFGDLCSGKIKKVRKEYCLEQLTPGEDRHEWE
                     EIQVMAEYDASGKPKALIGSTISITERKQLEHDLRMARDKAEESNKLKSAFLANMSHEI
                     RTPLNAIVGFSNILASTDDLEDKKEFADIIENNNSLLLQLINDILDLSKIEAGTLEFTY
                     DYVDINAVLRDLEQSVHLKNKNPDVQISFQDYLEPCVIYTDRNRLSQLMINLLNNAMKF
                     TKTGSISFGYKLRDDNTLWFYVEDTGCGIPENKRKDIFGRFVKLNTFAQGTGLGLSICE
                     MIVTQMKGTIGVDSVEGKGSKFWFTLPFQPKKELLPAGEPKPVTLDKIARNELTILIAE
                     DNSSNYRLFESILKPEYKLIHAWNGKEAVELFHQHKPQLILMDIKMPVMDGYEATAEIR
                     KVSSSVPIIAVTAYAFAQDEQRIIKSGFDAYTAKPINGKILKDKISTLLTYRIILM"
     CDS             14316..15092
                     /locus_tag="ctg137_12"
                     /transl_table=11
                     /translation="MELMDMKDYDIDFKEKRTNGYLIATLFIIVGILFLLRNLGMIDPS
                     LFDLLVSWPMLLVVSGIFTIFHRNPVGGMLLVGVGVYFLFPQLNWITNDFLRIYWPLGL
                     ILLGLVIMLKRKDSIRTKKHKRPFNHPPFGHRKPNDEINYETDNGFVSVDTTFNSVRHI
                     VLDPVFKGADIDVSFGNVILDLKKTTLEADETIINIDSSFSGVVIYVPKGWLVRLKVDS
                     FLAGCQDMRDLTETTDMTHTLYICGDLSFSGLELRD"
     CDS             15100..15894
                     /locus_tag="ctg137_13"
                     /transl_table=11
                     /translation="MQEHPITTSILHKGLGSLLLLLAIAIQCALLTLYGDLLLSITLVD
                     SLLSIALFAVAGYYLWYVQCTLHIMQARVAFAVLVQIACIAGCSILLQIFGLEDWEEFS
                     ITIPFRFLFGLMAWIILSQWYASRERKSEAEPIVRQMEEKTAPPPTTVPEEILDRISVK
                     DGTRIHIIPIKEIFYLQACGDYVTLFTTSGQHVKEQTMKYFERSLPSPEFVRIHRSYIV
                     NTEQILRVELFGKETYQVRLKDGTYLRASSAGYKLLKERLSL"
ORIGIN
        1 aattcaccct actttgggtt ttacggaatt cgatattctg gaaaaatacc gtaagagttt
       61 taaagagagc gaacttggca ggcttcattc cgtgtttcca ttcaacagta cagcgaaaga
      121 ggccggcctg tctcagcacc gtcttggccg caggaactgt ttcattcctt cagcaaagat
      181 agcccttatg gaactgaagg cctatactgg attttccgag cggcggctgg tggaacatct
      241 taaaaagata aaagaacacg attatttacc gaacagttaa aatacacaat atgcccactt
      301 tgcacgtaaa tattggcata tagctgatat ctacacagtt atgcatatac acctattacc
      361 gatccaatta ctatctataa taaatcagat tactatcaat agtaaatcgg atnnnnnnnn
      421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      541 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      601 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      721 attactatca atagtaaatc ggattttcta tagatagtag ccatgaatac tatagcttct
      781 atcgctagat tattacaaga agtacaaccg agtgatacac attgaagtca gataagcgaa
      841 tagaacacaa aaaccggatt gccctcctct ccttttaagt ccaactcctg cggaatcgtg
      901 attgagcgaa gcgatttata taagtttagc tcatatgggg tcactacttg taccagctca
      961 tcttttatga ccctccccca gaccgggaaa ttccgataac ttctcgtacc ctgcatgcca
     1021 tgttgaaggt tcgcatccgc cagttcatag atagaacccg gcatctcaca tttttccaca
     1081 agtgtctttc ccgtcttttt atctacagag gctatataat agccttggtt atacaataaa
     1141 cggaaataat aatgttccgg aaactcaatc atatcttgca caaagatatc cttgggggcc
     1201 tttttttcaa ttcgcaaatt actcatgtcc gtaacatcca acgaacgaat cacttccgca
     1261 tccgagtttt tcagatcaag gacacaagcc gcacttattc gatccgccga gatactgaag
     1321 accgtataat tgctaccggt cttaaacaac acggagtttt gcgcatcaga ataagcgggg
     1381 gcgatacttg tcgtgaaccc gctcttctca tgaggtaata aaaaggaata aaaatcattc
     1441 ttgatcgcta tcgtatcccc tttcctcgaa aataggccca atccgaatcc ccctccgttg
     1501 aaaggctgaa aagggaatga tatggcggcg aaacgatcct ttccgatatg acgcatatag
     1561 attacagaat actcatgggt ggattgtccg ataaattcac cttccaacgt atattcccaa
     1621 actcgattat tactaaataa aaaaaggcgg tcattacgtt cgtccacttg gatacatggc
     1681 agaataccgc taaattcacc cggcccctgc ccttctttta ccaacgtccg gataaaacgc
     1741 ccttgccgat cgaacaggac gatacggggc tcttttacgg gaagcacata gatatatcga
     1801 tctgtcacgg cataatcata aactccgtct atcaacgagg catcatccgt ggtcacctct
     1861 aaagggacaa aagtaacccc cttgatctca tcgcctaacc ccaatagacc cggtttatcc
     1921 atccctcctc ttatatccgc agttaaaaga aaggacgctt ccgttggcga agaaccgcat
     1981 gacacgaaac aagaaacgac aaaaacacta tttaaataaa acaagataga ggctaacttt
     2041 acacttttca taaccatgct tttttgcctc caaaaatatc ccgcatatct cacaaatcac
     2101 atgataaatg agaacaaaaa tgagaacaaa cctgccaata ccgctataaa tacataataa
     2161 tcaaaaactt gagataaact ccacaaatgt ctccgtagaa ccttctttct taaaaatctt
     2221 ccggaataga cgaggacgaa gtaccgaact attatatttc aatacccgtg tgatctggtt
     2281 ggcgggaacg ccgatcttcg taagcataca gaccttcaac tccgtatcgg aaatagcagg
     2341 atatagtttt ttcagccgta aggtaaagtc atcataagcc ttattcaaca gcacctccaa
     2401 aagctcccaa tcctcaaaga caatcttgcc ggcatcccga tcgtgaaact tctcatagac
     2461 ctccgatttc cgcaagatcg caacagataa taaatgctta ctctccttat tatgaatcga
     2521 ctcgttacaa atctccagtc gttgtttctc caattgtaag gaaaccaaca tcaactcttg
     2581 atccttttct tcctttattt tcgtaattct cttttccaaa agggcgattt gccgttcatt
     2641 ctcttctttt tcttctcgca tacgttgttg ctggctagca atcgagcgtc gcaaggcttc
     2701 ttcccttcga agagcgtttt cctgcgtatt tctccatcgc cgataaagga ggaagcaaat
     2761 aaatagaatt atgccgataa taaacgcgta cagataacgc tcctgtcccc tttgcgatag
     2821 catcaattct ttcctataca agtcctcacg aaccggcctt acatcatacc gggaagtgat
     2881 ctgataaatc gattctctcg ctgacagcga tccgatagaa tcccgtaacg cctcgtattt
     2941 cttgacttcc tccagtatcc ggccttgtcc ggccgtatca ttcaagagct gatattgggc
     3001 actcgctttt ctcaaaaaag acatggcctt gccatataat tcctgctcgg cgtacagcct
     3061 ccctatctgg ttatataacc gtccccaaaa ttcgtaatcc caattccctc cctcatattc
     3121 caacgcacgt aaatagcatt ccaaagctag ggacggttga tccatatcct catagacttt
     3181 cccccggtaa aaccacgctt tgggaggcca gtaacagcct cgtgtcgtcc tataataatc
     3241 cgtagcgata gagattatgg aatccgatgt atgcctcaat cccgcctcat cccgtgattc
     3301 ggtccataac agacaataac gggctttctc tcgaagcgat aatccattga tatccgtcac
     3361 tttctctaat aacaccaaag cgctgtccgg atgatgcgga atcaatttct ctacctgcca
     3421 gaacaggttg ccatgcttgt cgctcctata cgaaaaaagc acaagaacca agatcgcaat
     3481 cgtaaacaat aagatcgtga acttaatccc tatggaaaaa tgccgtggcc cattcaaatc
     3541 cttacgcata taggcaaatg tatataaatt attcataagg aaaacctttt ccttccgcat
     3601 tatttcatgt gtcggggcac atgtcctgac ctctcctatt aatgcagaaa tatttcttta
     3661 atcgtttgcg cgatatatgg atttagcata cctttgcgtg ataattacat agtttaagta
     3721 gaaatttcta aatacaatta aataacttaa attattatct tatgtggtta cttaattctt
     3781 ctatcgggaa gaagctgata atgagtatat caggcctctt tcttgttctg ttcttattgt
     3841 tccacctgtc gatgaacgtg gcggccgttt tctccggaga ggcttataac atggtttgtt
     3901 cgctgttggg ctctaattgg tacgctgtgg cagctactct cgtattggcc gcaggcgttg
     3961 tgatccactt cgtgtacgct atcattctta ccttgcaaaa ccgtaaggca cgtggtaacg
     4021 accgttacgc tatcaacgct cgtccgaaag gcgtggaatg ggcatctcag aacatgttcg
     4081 ttttgggttt gatcgttatc ctgttcatgc tgttgcactt cagccagttc tggtataaga
     4141 tgatgttcgc cgaattgatc ggtcatcacg aagtagcatt ggggtcagct atggtatctc
     4201 cacaagacgg agccgctttt atcaactatt acttccaagg taatgccatg atcaccgttc
     4261 tttatttgat ctggtacgtg gctttgtggt tccacttgac tcacggtttc tggagcgcta
     4321 tccaaacaat cggttggaat aacacgatct ggatgaaccg ttgggaatgt atctctaaga
     4381 tcgtagctac ggttatttgc ggacttttcg cgatcattac tatcatcttc ttcctaaacg
     4441 gagtaggtgc ttaattgcaa gctacaggtt ttataattaa gaacttttga aattaaatca
     4501 ttatgtctga aataaattct aaaatacctc aaggcccgtt ggctgagaag tggactaatt
     4561 ataaaaatca ccagaaattg gtgaaccccg ctaacaagcg tcgtttggat gttatcgtag
     4621 tcggtacagg tttggccggt gcttccgctg ccgcatcttt ggcagagatg ggattcaacg
     4681 tattgaactt ctgtatccaa gattctcccc gccgtgcgca ctctatcgcc gctcaaggtg
     4741 gtatcaacgc cgctaagaac taccagaatg atggtgactc tgtttaccgt ttgttctacg
     4801 atacgatcaa aggtggtgac taccgtgctc gtgaggctaa cgtttatcgt ttggctgagg
     4861 tttctaactc aatcatcgac cagtgcgtgg ctcaaggcgt tcctttcgct cgcgaatatg
     4921 gtggtttgtt ggataaccgt tcattcggtg gcgctcaggt atcgcgtacg ttctacgccc
     4981 gtggccagac gggtcagcag cttttgttag gcgcttattc agcgttgagc cgtcagatcg
     5041 gtttgggtaa ggttaagatg tacactcgtc atgagatgtt ggatgtagtt aaggtagacg
     5101 gtcgtgctcg tggtatcatc gcccgcaact tgattacagg taagatcgag cgttacgccg
     5161 ctcacgctgt agttgtagct acgggtggtt acgttaatac gttcttcttg tcaaccaacg
     5221 ctatggcatc taacggttcc gccgcatggc aatgctacaa gaaaggcgct tacttcgcta
     5281 atccttgtat ggttcagatc cacccgactt gcgttccggt acacggtgat tatcagtcta
     5341 aattgacttt gatgtccgag tctttgcgta atgatggtcg tatctgggtt ccgaagaaac
     5401 tggaagacgc taaggcttta caggcaggaa caaagaaagg taaagatata cctgaggcag
     5461 atcgcgatta ttatttggag cgtcgttatc cggcattcgg aaacttggtt cctcgcgacg
     5521 tggcttctcg tgccgctaaa gagcgttgcg acgctggctt cggtgttaat aacacaggtt
     5581 tggctgtatt cttggacttc tccgacgcta tcaaccgtct gggtaaagag gttgtaaaac
     5641 agaaatatgg taacttgttc gatatgtacg aagaaatcac caacgacgat ccatacgaaa
     5701 ctccgatgat gatctacccg gcattgcact attcaatggg tggtctgtgg gttgattatg
     5761 aattgatgac ttctatcccg ggtctgttcg ctatcggtga ggcaaacttc tccgatcacg
     5821 gcgcaaaccg tttgggtgct tccgcattga tgcaaggttt ggccgatggt tacttcgtat
     5881 taccttatac aatccagaac tacttgtcag accagattca ggttccgcgt ttcagtaccg
     5941 atctgcctga gttcaacgag gcagagaaga atatccaagc ccgtatcaat aaattgatga
     6001 gcatcaaggg taaagagtct gttgattcta tccacaaacg tttaggacac atcatgtggg
     6061 aacacatcgg tatggctcgt aacgcagaga gcttgaaaga ggctatccag atgttgaaag
     6121 acttgaagaa ggaattctgg agcaacgtat tcattccggg taacgcagat gacttgaacg
     6181 tagagttgga gaaagcgtta cgtttggcag actttatcga gatcggtacc ttgatggcac
     6241 atgacgcttt agaccgtgct gaatcttgtg gtggtcactt ccgtgaggag caccagactg
     6301 aggaaggcga ggcattacgt cacgatgaca aattcatgta tgtctcttgc tgggaatatc
     6361 agggtgagga taaagaccct gttatgctga aggaagattt gaactatgaa ttcgtagttc
     6421 ctcagacacg taactataag aagtaatcaa tcattgcaaa aattagaatc atggataaag
     6481 atataaatat cacactcaaa gtttggcgtc agaaaggtcc gaatgtaaaa ggacaattcg
     6541 aaacttacca acttaaaaac atcaaccaag gcacttcttt cttggaaatg ttggatatcc
     6601 tgaacgagca attaatcagc gaaggtaaag aacctgttgt ttttgaccat gactgtcgtg
     6661 aaggaatctg cggtatgtgt tcattgtatg taaacggaca tccgcacgga ccggcaactg
     6721 gagctacgac ttgccagtta tacatgcgcc gtttcaacga tggtgagacc atcacgatcg
     6781 aaccgtggcg ttccgccggt ttcccggtaa tccgcgactt gatggtagac cgttacgctt
     6841 acgataaaat cattcaggcg ggtggtttca catccgtaaa taccggtggt gtacccgacg
     6901 caaacgcaat tcctattcct aagccagacg cagagatggc aatggatgcc gctgcttgta
     6961 tcggttgtgg cgcttgtgcc gccgcttgta agaacggttc agctatgttg ttcgtatccg
     7021 ctaaggttag ccagttggct ttattacctc aaggtaaggt agaggctgcc cgccgtgcga
     7081 aagcaatggt cgctaaaatg gatgaacttg gcttcggtaa ctgtacgaac acacgtgctt
     7141 gcgagatgga atgtccgaag aatatctccg ttagcaacat cgctcgtttg aaccgtgagt
     7201 tcatttgcgc taaattacaa gactaatatt tgattagtat atcatggaaa aggcgtcttt
     7261 ctctaaaaga aaggtgcctt tttatttttg ttatatgttg aaaaacataa tttagcacta
     7321 cagatcttga caggaattga aaagtccgta tatttgcatc gtggttttnn nnnnnnnnnn
     7381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7441 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7741 nnnnnnnnnn nnnnnnnnnn nnnncaggct ttaattgttt atagacctac cttttaaaca
     7801 tggaccacaa aatactgcaa atagagattg tttagcgtca ttttatcgtc gatctttgcc
     7861 tttaaagatc atataatata tgctaataag tattttattt ggcttcttat gttattttct
     7921 ccgggtgttg atcaaacaca aggaaaaaat catgcgccag ataagacaaa tggtaaaaca
     7981 aaaataaaat ggacaaaaaa cgaaccacca gttctttcag ggcaatgagc acggaaagaa
     8041 aactcgagtc gatcttcctt ttcgtaacag gccgatgcaa cgccaaatgc gcgatgtgct
     8101 tctatgccca agaaatggat aagaagcaac ccgacctcac tttcgatgaa atcaagaaaa
     8161 tatcagaaac cgctgggcaa ttcaaccgat tatggatatc cgggggtgag cctaccctgc
     8221 gtgaggatct accggaaata ttggagttat tctacaaaaa caaccatatc aaagatgtga
     8281 acatccctac gaacggctta aaaccagacc ggatcgtcga atgggtaaaa cggttccgcc
     8341 agaactgccc ggattgtaat attaacgtaa gcctttcctt ggatggtttc ggtacgaccc
     8401 acgatacaca gagaggcgta ccgggaaact tctataaggc actggaaacc ctgcgtaaga
     8461 tacaggagaa tttcggagat gacggcaagg tcctgaaaaa tatagcaacc gttatcacga
     8521 aatacaatat agaccaggta gaagacttca tgacttgggt atacggacgc ttccgtacct
     8581 ccacacatac gattgaggcc gccagaggca tgacccgtga cgatggcgtg aaaatcctaa
     8641 ccgagtcaac gctacgcaaa atacaagacg acatatcccc tatctattca gcttatgcgg
     8701 atcggatggt agcggatacc accggcttaa ggaaaccgat cacgcacttc ttctatctcg
     8761 gccttatacg taccttatat aatgtacgtg ccagcaacat agatcaccca accccttggg
     8821 ggatggattg tacggccggg gagactacct tggtaatcga ctacgacgga cgttttcgtg
     8881 cctgtgagtt acgggaaccg ctcggaaata taaaagagta tggttgcgat ataagtaaag
     8941 tgatgaatag cgaagcgatg aaacaggaaa tagccgctat cggacatggg tataaagcca
     9001 actgttggtg tacgcacggc tgctggatca cctcatccgt cattttcaat ccacgtaaga
     9061 tgattcgctc cgtatataaa ggataccggg aaacgaaacg attgaatcat cccttagcca
     9121 tcaatgagca gaaactacaa acgatggaag ccaaatacca tctggacatc gagcgtttgc
     9181 gtcaactgaa tatccggtaa acaagaccct catagcccat aaataaacgt agcatgaaaa
     9241 tactattagt aaccagaggc tcacaaggcg acgtccttcc ttatttggcc atagcggccg
     9301 aattggaaag acgcggtcat gaggtgacca tcaatctccc tcaaatattc gaggagaccg
     9361 ttaaacccta cggatttaaa tacgtattgc aacagtttga cgatatcggc ggcatgatcg
     9421 atagcgcagc gcaaaactca cataaattcc ggccattcct taaatggatg cggaacgtga
     9481 tcgataaaca gttcgatcaa ttgattcccc tactaaaaga gcatgatatt ttagtatcga
     9541 ccaactcgga atttgctgtc gcaagtatcg ccgagtattg caagaaaccc ttgatacgta
     9601 ccgcctacgc cccgttcttg ccgggtaaga agattccccc ggccgtattg ccatttccca
     9661 aacccaaccc gatcatcact cccgctatcc tatggaagtt gatgaaccgg atgaccaatt
     9721 tcatggtcaa agacacgatc aataagaacc gggctaaata cggactcgcg ccgattcgca
     9781 attttggcta tcacgcggga gagcgttcat ataattactt gcttttcagc cagcacctag
     9841 gaaacgtaga tccggactgg acgttcgaat ggtcgatcgg aggctattgc ttcaatgaca
     9901 cttttcaata tgatgagaag gcttacgagg aaatgatatc attcgtcgac agcgctcaaa
     9961 gccctattat cttttttacc ctcgggagtt gtagttccaa ggatggtaac cgtttcagca
    10021 aagccttggt cgatatttgc aagaaacatg attatcggct catcatcggt tccggttggg
    10081 caaagacagg aatcacctta caagcggata aacatttatt cttaatgaag cagccggttc
    10141 cgcataattt gatattcccg cactgcgacg gcgttatcca tcatggaggt tgcggcacga
    10201 cccatagcgt aggaagggcg ggaaagcccc aattaatcac tccgttgatt atcgatcaac
    10261 cctattggtc ctatcgaatc caccaattag ggttagggcc ggaaggagtt aagatagcga
    10321 aagcgagcga gcaggagatc gaacgcaagg tttgtgatct ggtcaccaat ccgctttata
    10381 agaaaaatgc cgctcatata ggcgagatga tccaaaaaga gggaggtata aagaatatat
    10441 gcgactctat cgaaagattt caatgaggca taagttccta ttagatttta ttacatgtta
    10501 caaaacacaa tttagcactt aaactgttga caaataacag taactccgta tatttgcatc
    10561 gtggttttnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnntcgtgag acaggcttta attgttttat
    10921 gaggtctgct tcccgcaaag cccttcgatt acatcagaat aatccgatac gtcaataaag
    10981 tcgatatctt gtcttttaag atcttcccat taatcggttt cgccgtatag gcatcaaatc
    11041 cacttttaat aatccgctgc tcatcttggg cgaaagcgta agccgtcacc gcgataatag
    11101 gtacgctgga agaaacctta cgaatctctg cggtagcctc atatccatcc atgaccggca
    11161 tctttatatc catcaagatc aattgcggtt tgtgctggtg aaatagctcc acagcctcct
    11221 ttccattcca tgcatggatc aatttatatt caggtttcaa tatagactca aacaggcggt
    11281 aattactgga attatcctca gcgatcaaga tcgtaagctc attacgggcg atcttgtcca
    11341 aagtaacagg cttcggctct ccagcgggta ataattcttt cttcggctga aaaggcaatg
    11401 taaaccagaa cttagagcct ttcccttcca cggaatcaac cccgatcgtt cctttcatct
    11461 gggtaacaat catctcacag atacttaaac ccaatcctgt tccttgagcg aaagtattca
    11521 gtttcacaaa acgtccgaag atatctttcc gtttattctc agggattccg cagcccgtat
    11581 cctctacata gaaccacaac gtattatcat cccgcagttt atagccaaat gagatcgatc
    11641 ctgtcttcgt aaatttcatg gcattgttca acagattgat catcagttga gacaaacgat
    11701 ttcgatccgt ataaatcacg caaggctcca gataatcctg aaatgagatc tgtacgtccg
    11761 gattcttatt cttcaaatga accgattgct ccaaatccct caaaacagcg ttaatatcca
    11821 cataatcata agtaaactcc aaggtacccg cctcaatctt tgataaatcc aagatatcgt
    11881 ttatcaactg cagcaatagg gaattattat tctcgataat atcagcgaat tccttcttat
    11941 cctcaaggtc atcggtcgag gcgaggatat tagagaaacc tacgatcgca tttaacggcg
    12001 tacgtatctc atggctcata tttgctaaaa acgctgattt caatttattc gactcctccg
    12061 ccttatccct agccattcga aggtcatgtt ccaattgctt acgctcggta atagatatcg
    12121 tagacccgat caacgctttc ggtttaccgg aagcatcata ttcagccatt acctgtatct
    12181 cctcccactc atggcgatcc tctcccggag tcaattgctc cagacaatat tcttttcgta
    12241 ccttctttat tttcccacta cacaaatccc cgaaagcctt ttccacgcaa gccctgaaag
    12301 acgggtgtat cttgctgaaa tattcctcca acgaaacctc atgggtatgc acctctgctg
    12361 tctctatatt atctcccgga tgtactttcg actcatagat aatcttccct tcagccagat
    12421 tatatcgcca cggtaaaaga tctgccgcct ctaacgccat agccagctta tgattcatgg
    12481 ctttcaaatg cgtctggaaa ttatggatat ccgtaatatc aataaaaaac gcgtcaacta
    12541 cattctcttc cgaggtaggc atgatgataa cagtatagta aagccctgtc ggctcaaaat
    12601 aatactcaca agtaaaggat ttcccactct ccagaaccgt aggcacagcc gatagaagca
    12661 aaggataact tcccccaatc aaattagcga tctcttttcc atgcttattt accacgaaat
    12721 ctttaggagc gattttctcc tcgaaagcat ggtttacatc caaaacctgc acatcgattt
    12781 gcgtaccttc ccgaatcagc cgctgccgta tataaggcaa tggcatatta ttaaataaat
    12841 cgcggtaacg ggataacagc ctcaactcca cttccttcat cttttgctta gaacgataca
    12901 cgtaatgcca cgctaaaaac acgactacca gaaagaaaat cagaaagcct aacagcggca
    12961 tccaatattt ttctaaaaaa gagggaggcg cattcaaata gatcgcatca tgtgggaaat
    13021 tatcttcatt agacatcgcg ctcatcaacg aaacataatt caagtattta tgaggatcat
    13081 ccaccgttga aaccgggatc ttgcccatat cttcaccgtt atagacttgc tgtagcaagg
    13141 gaattagagc agtctcaatc gttttagtac tattataata tccaccaatc gtatatcctt
    13201 cttccacgcc catatcatat aaagaaaaaa caggatgcct agaaataccg tttatacctt
    13261 gatacaaagt actatataat aacgagtgat tcaagaaagg tttctcggta atccacgagt
    13321 aatacatcac tgccgtcgct cgatgtggat ctttctccga cagaaccgcc attaaactat
    13381 ccatggagca agaaccctcc gtataaaaat ccactttccc ctcagggaaa gaagtttcca
    13441 tatgtttctc catctcatcc cgaagccatg tggagacata acgtctgtcg gatatgaaaa
    13501 tcagacgtct caaacccggg attaattcct tcaccaagtc gatcgaacct ttaacataat
    13561 aaggaataac caaccccgta gcgttatacc ccttaaccgc ctcttgtaaa ggaatcaccc
    13621 tatcagagga gtgcctctga ttaaaatagc attcatcttc tgccatttca cccgtttccg
    13681 aacagaccag agagggaata tccccccatt cctcccggat cttatcccgc ataaaagccc
    13741 atccatttac gcctaagtag ataattccac ccggcttttc cttatacgtt tcaaagaaaa
    13801 gcttttgttt ttcttttaac ttctctggcg tatcaaccaa tattacgttc atatggtcta
    13861 ttcgaagagt atactcctcc ggagtagcga acttcgagat catgtttaat aaatttccag
    13921 accaacgttc gctatccata tatgaattta tcaccaatac atacgattcc tccttgaccg
    13981 gatatgagga actcccataa gccggagtcg gcataccggc tatcaagcat aaaatcaatc
    14041 caaaataaag tattattacc tttaaactta taatatttcg tatcattccc tacattcgtc
    14101 tattgcagtt gtaaagacaa agatattcct taattatcaa ctaatcttat caaactcgtt
    14161 tttttatcaa gttttggtgt caaattcacg tttcttacaa actaaaggct tttttaatcg
    14221 ggattattcg gttatttacc gatactcgta tagaaatcag cggtatttac ttgtgtatag
    14281 aatgacgaac ccgtacattt gataaaaaac aaaaaatgga acttatggat atgaaagatt
    14341 atgacatcga ttttaaagag aagaggacaa acgggtatct gatcgctacc ttatttatca
    14401 ttgtcggtat attattttta ctacggaatc taggaatgat agatccatcc ttgttcgact
    14461 tgcttgtatc ttggccgatg ctgcttgtcg tgtcgggcat ctttacgatt ttccaccgta
    14521 atccggtagg aggtatgctc ctcgtgggcg tgggagtcta tttccttttc ccgcagttaa
    14581 attggatcac gaacgatttc ttacgtatat attggccgtt aggattaatc ctgttaggat
    14641 tggtcatcat gctgaagcgg aaagattcta tccgcacgaa aaagcataaa cgtcctttta
    14701 accatccccc tttcgggcac agaaagccta acgatgagat caactacgag acagataacg
    14761 gtttcgtatc ggttgacacc actttcaact cggtaaggca catcgtactg gaccccgtat
    14821 tcaagggagc ggacatagac gtatctttcg gcaacgtgat cctcgatctt aaaaaaacaa
    14881 cattagaggc tgatgaaacc atcataaaca tagatagctc cttcagcggc gtagtaatat
    14941 acgttcctaa aggatggctg gttcgtctaa aggttgattc cttcttggct ggatgccaag
    15001 atatgaggga cctgacagaa acaaccgaca tgacgcacac gttatatata tgtggagact
    15061 tgtcgttcag cggccttgaa ctaagagact aaactcatca tgcaagaaca tcctattaca
    15121 acatccatat tacataaagg gctgggaagc ctattattac ttttagccat agcgatccaa
    15181 tgcgcattat taactcttta tggcgatctt ctgttgagca tcactttggt cgatagctta
    15241 ctttccatcg cattgttcgc cgtagcggga tattatcttt ggtatgtaca atgtacgtta
    15301 catatcatgc aagcacgagt ggctttcgcc gtactcgtac aaatcgcttg catagccgga
    15361 tgctcgatct tgctacaaat attcggattg gaagattggg aggaattctc gatcacgatt
    15421 ccttttcgat tcctgttcgg cctaatggca tggatcattc tatcccaatg gtatgccagc
    15481 cgggaaagaa agagtgaggc ggaacctatc gtgagacaaa tggaggaaaa gacggcacct
    15541 cccccgacta ccgttccgga ggagattcta gatcgtatat ccgtaaaaga cgggacacgt
    15601 attcatatca tcccgataaa agagatattc tatttgcaag catgtggcga ctatgtgacc
    15661 ttattcacca cttccggtca gcacgtaaag gagcaaacca tgaagtattt cgagcgaagc
    15721 cttccttctc cggagttcgt tcgtatacat cgctcttata tcgttaatac ggaacagata
    15781 ttgcgagtag aactattcgg aaaagaaacc tatcaagtac gattaaagga tggaacctat
    15841 cttcgtgcca gtagcgctgg ctataagcta ctcaaagaac gtctttccct ttagcagtcc
    15901 tataaaaggg acctaaccat cgttaaaatt agaagatttt gattgtaata tatagagttt
    15961 tgtgttgtgt aacacttttt ggcaagcatc gatatgttac ttaacatata ttagttgcaa
    16021 aagacttgac aaatggtctt gacgaacgta tctttgcatc gtggtttttt nnnnnnnnnn
    16081 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16141 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16441 nnnnnn
//
