LOCUS       c00108_gnlPro..        13703 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OCDEBFIB_108.
ACCESSION   c00108_gnlPro..
VERSION     c00108_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 00:22:43
            Original ID  :: gnl|Prokka|OCDEBFIB_108
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13703
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..540)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg108_1"
                     /sec_met_domain="ECH_1 (E-value: 1.2e-53, bitscore: 174.1,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METKREWTTIKEYEEILFDFYNGIARITINRERYRNAFTPTTTTE
                     MSDAFYICRERPDINVVVLTGAGDTAFCAGGDMNVKGRGGYVGKDGVPRLNVLDVQKQI
                     RSLPKPVIAAVNGFAIGGGHVLHVVCDLTIASENAIFGQTGPRVGSFDAGFGSSYLARV
                     IGQKKAREIWFLCRKYN"
     protocluster    1..13703
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:3703]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1..3703
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..13703
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13703
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             complement(544..2232)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg108_2"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.9e-07, bitscore:
                     21.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYSDKKNILQLVALLIEHGVSNIVLCPGSRNSPIVHTLANHSFFN
                     CHSVTDERSAGFFAVGLALHGGKPAAVCCTSGTALLNIHPAVAEAFYQKVPLVVISADR
                     PAAWIGQMDGQTLPQPGVFGSLVKKSVQLPEIHTDQDEWYCNRLINEALLELNHHGKGP
                     VHINVPISEPLFQFTTPELPKVRVITRYQGLNVYDRKYDDLIERLNKYSKRMMIAGQMS
                     LIYLFEKKICKLLYKHFTWLSEHIGNRIVPGLPIKNFDAILYATPEEEKEKLVPELVIT
                     YGGHIVSKRLKEFLRKHPPKEHWHVSLDGEVADLFGSLTTVIEMDAFEFLEKIAYMLEN
                     RQIEYPKAWEYKSRNLPEPEFAYSEMAAIGGLIRSLPAESALHLGNSSTVRYAQLYTVP
                     ETVEVCCNRGTSGIEGSLSTAIGYASASQKLNFIVIGDLSFFYDMNALWNGNLHNNLRI
                     LLLNNGGGEIFQALPGFKMNERTHRYVTASHQTSAEGWATERGFSYSAVHNAEELAAAM
                     SAFTQTEQPSEHPLFMEVFTDKAEDVRLLKEYYHQLKNSSQAQNI"
     CDS             complement(2247..2825)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg108_3"
                     /sec_met_domain="Chorismate_bind (E-value: 3.2e-46,
                     bitscore: 150.0, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGGTPEILLSGEKGDWQTVALAGTQSLRDGKLPKSWDHKNWREQQ
                     LVASYIRRQLSTLGITPEEKGPYSARAGEVSHLKSDFFFSLPNPEKLGDVLQLLHPTPA
                     VCGLPKEEAYHFIIENEGYDRSYYSGFIGWLDPKGKTDLYVNLRCMNILPQTFTLYAGG
                     GLLAASQLEDEWQETEDKLDTMRRIVGNL"
     CDS             complement(3341..3703)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg108_4"
                     /sec_met_domain="HBT (E-value: 6.6e-18, bitscore: 57.1,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGNLGIQYTYASEDRVEATMPVDERTRQPFGILHGGATLALAETV
                     AGLGSMILAKPDEMVVGMQVSGSHMSSAHEGDTVRAVGTIIHKGRSSHVWNVDIFTSTD
                     KLVSSVRVINSILKKK"
     CDS             complement(3736..4587)
                     /locus_tag="ctg108_5"
                     /transl_table=11
                     /translation="MKYKLLVLDVDGTLLNDKKEITPRTHAALLKAQQMGVHVVLASGR
                     PTNGVQPLAEALELNHYGGFILSYNGGQIINAQTGELMFEKRIDPAMIPYLNRKAKENG
                     FAIFTYHKDYILTDSPENKHVQEEAELNKMRIIGVENFPEAVDFAPCKCILTSDDENNL
                     VGLENHWKKRLDGVLEAFRSEDYFLEVAPHFINKGNTLAVLMEMLNITTEEVVAIGDGV
                     ADVSMLQLAGTGVAMGNARDSVKACADFTTLSNNMDGVAVAMXXXXXRKRSLPRSNPRR
                     FR"
     CDS             complement(4846..5652)
                     /locus_tag="ctg108_6"
                     /transl_table=11
                     /translation="MNYKLLVLDLDGTLTNSKKEITPFTRETLLQAQEKGLHLVLASGR
                     PTYGIVPLAEELNIKQYGGFILSFNGGKVIDLMTDKVLFEQALPPDIVPVLYNRSKEAG
                     LAILSYNGKYILSEHPENKYVQYESFLTKMKIKATDDFLRDLHQPADKCLVVGEPEMLV
                     PLEEKLRQELGKRINVYRSEAFYLELVPKGIDKAASLSRLLERTRIKQEEVIAIGDGFN
                     DVSMIRFAGLGVAMANAQPPVKANADRITQYTNDEDGVARFIQELL"
     CDS             complement(5642..7564)
                     /locus_tag="ctg108_7"
                     /transl_table=11
                     /translation="MGISSPLVDLQHQYDLLQKEYEYEKETYRQQSERTGLRKRVAQGL
                     CWYPVTPGRSYYNSLNQLVIEIERTEDREIEHNFEYGRPVCFFTADISGKFKYLDFSAT
                     ISYVQEDRMVVVLPTPSALMDIQGKSNDLGVQLYFDETSYKTMFSALSDVMRAKNNQLS
                     HLRDVLLGQEKPGQRELFPIRFPWLNRSQEEAVNKVLGAKQVSIVHGPPGTGKTTTLVE
                     AIYETLHRENQVIVCAQSNTAVDCISEKLVDRGINVLRIGNPTRINDKMLSFTYERRFE
                     SHPDYPELWSIRKAIRDIQSNMRKKSREERDTIRNRLSRLKFRATELEVKIDTELFDEA
                     RVVACTLVGSANRVMMNRHFTTLFIDEAAQALEAACWIAIGKADRVILAGDHHQLPPTI
                     KCIEAEREGLGRTLMQKIAHTKPETVSLLKIQYRMHEDIMRFSSQWFYHNELESAPEVS
                     GRGILRLDTPIVWFDTSECDFTENTREETMSRVNRQEAELLVEQLRSYIQKISKERVLE
                     ENIDFGLISPYKAQVQYIRKLIKQDAFFKPLRRLITVHTVDGFQGQERDVILISLVRAN
                     EDGKIGFLNDLRRMNVAITRARMKLMILGDASTLTRHAFYKELYNYISQRGKIITINTK
                     QEHEL"
     CDS             7750..8121
                     /locus_tag="ctg108_8"
                     /transl_table=11
                     /translation="MNENDAFYNALIDVAAWDKENTLDRFMNSDSLFKKFLYKFITTDG
                     SYVKLRSSLVERDLENAKLYSHTLKGIAANLGLVNLFDVSNNILSLLREGNLEEALRYE
                     DALGKQYDALRDIVVEFCS"
     CDS             8166..9458
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SDH_alpha"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg108_9"
                     /sec_met_domain="SDH_alpha (E-value: 5.9e-60, bitscore:
                     195.2, seeds: 645, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTIIKTQIIDLIHREVIPAIGCTEPIAVALAAAKAAEVLGRKPE
                     KIEVYLSANILKNAMGVGIPGTGMVGLPIAIALGSIIGKSAYGLEVLKDLTPEGLKEGK
                     EMVCKKCIGIDLKENVDKLYIEIISSAGNDRSRVIICHEHTHIIYVEKNGEVLTDLRMA
                     NASGEEVCENKDLRLSFSMVYEFAMEMPLDEIRFILETAELNKKAAQASMKGNYGHTVS
                     KTVSGAFGRKFMGDSAYTHMLIMTSAACDARMDGAMIPVMSNSGSGNQGIAATLPVLSF
                     AEDIQCSEEQLIRALMLSHLMVIYIKQSLGRLSALCGCVVAATGASCAITYLMGGNKAR
                     ISYAIKNMIGNITGMICDGAKPSCAMKVSSGVSTAMLSALMAMEDKVVTSVEGIIDEDV
                     DKSIANLTAIGSKGMEATDRLVLDIMTGKSC"
     CDS             9468..10370
                     /locus_tag="ctg108_10"
                     /transl_table=11
                     /translation="MEEAPKARKKEIMRVTLLGSFANFVLLVFKFVAGIWGHSSAMIAD
                     AVHSLSDFVTDIIVLLFVNISSKPKDESHDYGHGKYETLATSIVGIVLLCVGFGLFWEG
                     ANKIYDFYFKGIPLESPGMIALVAALISIVIKELLYHITVWVGRKQNSQVVIANAWHHR
                     SDAFSSIGTALGIGGAILLGDNWRVLDPLAAVIVSLFIVKVALQLVIPAINDLLEKSLP
                     KEVEDEILAIISEIPEVKSPHNLRTRRIGNNFAIEAHIRVDGQITVTRAHDLTKEIEQN
                     LRDKFGQATHIALHVEPIK"
     CDS             10383..11723
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg108_11"
                     /sec_met_domain="Amidohydro_1 (E-value: 4.1e-69, bitscore:
                     225.6, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LTMMKNLYRGEVLYLIASPLDHVEAYRYFEDGGLAVVDGKIVEAG
                     PFEAMRSRYPDFPVTDYSGKLITPGFIDSHIHFSQSEIQGMYGKQLLDWLDEYTFPAEE
                     AFSSMEYAQDIARFFVKELVKNGTTTCAAYATVHPASVTALFSVATEYNMCILAGKVMM
                     NRNAPDYLMDTTHQGELDCRSLIEDWDGKGRNHYVITPRFAITSTPDQLKSAGRLHAEY
                     PSTYIQTHLSENLGEIESVLSLCPGHADYLEVYERAGLLTDRSIFGHCVHLTDREYKRL
                     GETGGIIAHCPTSNLFLGSGLFDMREANRYGVRTTLATDVGAGTSFSMWRTMGEAYKVQ
                     QLNGYPMTALEAIYKCTLGSARALSLDDRIGSFLPGREADFIVVDYAATSVQKLRMEYL
                     RSRDKWTIENKLFGLQTLGDDRNTVCTYIMGKQVYGSDSCDHQEASM"
     CDS             complement(11688..12656)
                     /locus_tag="ctg108_12"
                     /transl_table=11
                     /translation="MKTRRIVISTVLLVGGLLSIVQVMPKNPLLIGERLFPYGGWIQVI
                     LAMLYGGWLCYKMQDRQERPKWRKRAWLLFSIVFFGQLALGIFADPIFLMTGKLHLPIP
                     AVILAGPLYRFEGLFMPILFISTLLLSGPAWCSQLCYFGAFDAWSARGKLERKRFPYHK
                     QMRYSILFLVMLGAILLRIFGASGRIATAFGIAVGVIGLLVMLLFSRKRRKMVHCSSYC
                     PIGTLVSFLKYLSPFRVRLTTDCCHCMACTNACRYDALHKEEIEKGKIGYTCTYCGDCL
                     SACKHGAIEYHFPRLRPTTAERLWIVVTVVLHTCFLMIARI"
ORIGIN
        1 attgtacttg cggcatagga accagatctc acgggccttt ttttgtccga tcacacgggc
       61 gaggtaagaa gagccgaacc cggcgtcgaa gctacccaca cgagggcctg tctgtccgaa
      121 gatagcgttc tcggaagcga tcgtaaggtc acaaaccacg tgcaatacgt gtccgccgcc
      181 gatagcgaaa ccgttcacgg ctgcgatgac gggtttcggg agagagcgga tctgcttttg
      241 tacgtccaat acgttcaagc gaggtacgcc gtctttaccc acgtagccgc cacgtccttt
      301 cacgttcata tcgcctcccg cgcaaaacgc cgtatctccg gctcctgtca gaacgactac
      361 gttaatgtcc ggacgttccc ggcagatgta aaaggcgtcg ctcatctccg tggtcgtagt
      421 cggggtaaaa gcgttgcgat accgttcccg gtttatcgta atgcgggcga tgccgttgta
      481 gaaatcaaat aagatctcct cgtattcctt gatggttgtc cattctcttt tcgtttccat
      541 atattatatg ttttgtgctt gggatgaatt ttttagttga tgataatatt ccttgagcaa
      601 tcgtacgtct tccgctttgt ccgtgaaaac ctccatgaat aggggatgtt cgctcggttg
      661 ctccgtttgg gtaaaggcgc tcatcgcagc tgccaactcc tcggcgttat gaacggcgga
      721 gtaggagaat cccctttccg tggcccatcc ctccgctgag gtctggtggg aggcggtgac
      781 gtaacggtgc gtacgctcgt tcatcttgaa tcccggcaag gcttggaaga tctcgccacc
      841 tccgttgttc aagagcagga tgcgaaggtt attgtgcaag tttccgttcc acaatgcgtt
      901 catatcatag aagaaactaa gatcgcctat aacgataaag tttagttttt gcgaggccga
      961 ggcgtatccg atggccgtag acaaagagcc ttcgatcccg ctcgtacctc ggttacaaca
     1021 aacctcaacc gtctcgggta cggtgtacaa ttgcgcgtaa cgtacggtgg agctattccc
     1081 cagatgcaag gcagattcag ccggaagcga acgtatcaaa ccaccgatcg ccgccatttc
     1141 ggagtaagcg aactccggct ccggcagatt ccgggattta tattcccaag ccttcggata
     1201 ttcaatctgc ctattctcca gcatataagc gattttctcc agaaactcga aagcgtccat
     1261 ctcgatcacc gtggtcaggc taccgaataa atccgctacc tccccatcca atgagacatg
     1321 ccaatgctcc ttaggcgggt gtttccgcaa aaactctttc agccgcttgg agacaatatg
     1381 gccgccgtag gtgatcacga gctcgggaac cagcttctct ttttcctcct ctggggtagc
     1441 gtacaggatg gcgtcgaaat tcttgatcgg caatcccggt acgatacggt tgccgatgtg
     1501 ctcggagagc caagtgaaat gcttgtatag taacttgcat attttcttct cgaagagata
     1561 gatcaagctc atttgtcccg ctatcatcat tcgcttgcta tatttgttca aacgctcgat
     1621 cagatcgtca tatttccggt cgtacacgtt taggccttga taacgggtga ttacccgtac
     1681 cttcggcaat tcgggtgtcg tgaactgaaa taaaggctcg gagatcggga cgttgatatg
     1741 aaccggccct ttgccgtgat ggttcagttc caacaaagcc tcgttgatca atcgattaca
     1801 ataccattca tcttgatccg tatgtatttc cggtagctgt accgatttct tcaccagcga
     1861 gccgaacacc ccgggttgcg gcaaggtctg tccgtccatt tgcccgatcc atgcggcggg
     1921 gcggtcggcg gatatcacga caagcggaac tttctgatag aaagcctccg ctaccgccgg
     1981 atgtatattc agcaaggccg tgcccgaggt acagcaaaca gccgccggct tacctccgtg
     2041 caacgctagc cctacggcaa agaatcccgc gcttcgctca tccgtcacgg aatggcaatt
     2101 gaagaacgaa tggtttgcca atgtgtgcac aatcggagag ttccggctcc ccggacatag
     2161 cacgatatta cttacgccgt gctctatcag caaggctacc aattgaagga tgttcttttt
     2221 atcgctatac attatatgat ataaaattat aaattaccca ctattctccg catcgtatct
     2281 aatttatcct ctgtctcctg ccactcatcc tctagctgcg aggccgccaa cagaccgcct
     2341 ccggcataca gcgtaaaggt ttgggggagg atattcatgc aacggaggtt tacgtacaga
     2401 tctgttttgc ctttgggatc cagccaaccg atgaaaccgg agtaatagct acgatcgtac
     2461 ccctcattct cgatgatgaa atgataagcc tcctccttgg gaagaccgca aacggctgga
     2521 gtagggtgta atagttgaag gacatcaccc agcttctcgg gattcggcaa ggagaagaag
     2581 aaatcgcttt tcaaatggga aacctctccg gcccgggctg aataaggccc cttctcctcg
     2641 ggagtaatac ccaaggtgga cagctggcgg cgtatatagg aggcgactaa ttgctgttct
     2701 ctccaattct tatggtccca gcttttcggt aatttcccgt ctcgtaagga ttgggttccg
     2761 gccaaagcta ccgtttgcca gtcgcctttc tcgccggata acaagatttc cggtgtccca
     2821 cccatccaag ttccggtttc cggggtatgg caaaggtaga cataggagcg gatatatcgt
     2881 tctactgcgg cgaagaatgc cttgccgggt gagaaagagg gatctttccg gatcgttttg
     2941 ctacgggata ggactagttt atcttggctt ccttttagca aagggctggt aaacagggag
     3001 aaatggtaag cgtatcgttc cttctcctcg gattcggatg ggatttcgat ttcattcgaa
     3061 gggaattcgt ttttctctcg agagaaatcc caatcggatt cggaggggat ttcaaagcaa
     3121 tccggttgga ttaaaacgat aggtcgttcc gctgtcacct gaaacggagc gattacaaaa
     3181 ccgctccgtt catttaagtc ttttatgtcg tataataggc aaggagagcc ggcgctttgc
     3241 atcctgaaat ggagcctatc ctcaccggga atacgccaaa tagcgaaact ccggccttgc
     3301 ttgatcaacg tgtctattat ttcgtaagaa tctcttggaa tcatttcttc tttagtatgc
     3361 tattgattac ccgtaccgag gaaaccagtt tgtcggtaga ggtgaatatg tctacgttcc
     3421 acacatggga tgaacggcct ttgtggataa tcgtcccgac ggcacgtacc gtgtctccct
     3481 cgtgggcgga cgacatatgg ctgccgctaa cttgcatgcc gactaccatc tcgtccggtt
     3541 tcgccagaat catggaacct agtccggcca cggtctccgc caaagccagc gtagcgcctc
     3601 cgtgcaagat accgaaaggc tggcgggtcc gttcgtctac aggcatggtc gcttccacac
     3661 gatcctccga cgcataggta tattgaatgc ctagattacc cattaaggca tgtttggccc
     3721 gtgcgtttag ttgatctaac ggaacctccg tgggtttgat cgtggcaagg atcgctttct
     3781 cgnnnnnnnn nnnnncatcg ctaccgccac accatccata ttattagata aggtcgtgaa
     3841 atcggcgcaa gcctttacgg agtcgcgtgc gttacccatc gccacgccgg taccggctaa
     3901 ttgaagcatg gatacgtcgg ctacgccatc accaatagcg acaacctctt cggtcgtgat
     3961 attcagcatc tccatcaata ccgccaacgt atttccctta ttgatgaaat gaggagctac
     4021 ctccaagaaa tagtcctcgg agcggaaagc ttccaatacc ccgtccagac gtttcttcca
     4081 atgattttcg agacccacta gattgttctc gtcatcgctg gtaagaatac acttacaggg
     4141 tgcgaaatcc accgcttccg ggaaattctc cacaccgatg atgcgcatct tattgagttc
     4201 ggcctcctct tggacatgct tgttttccgg gctatcggtc aggatatagt ccttgtgata
     4261 cgtgaagata gcaaaaccgt tttccttcgc cttccggttc aaataaggaa tcatggccgg
     4321 atcgattcgt ttctcgaaca tcaattctcc ggtctgggca ttgatgatct gacctccgtt
     4381 ataagataat atgaaaccac cgtaatgatt caattcaaga gcctccgcca agggttgaac
     4441 cccgttggtg ggtcggccgg atgccaatac aacatgaact cccatctgct gagcctttaa
     4501 cagggcggca tgggtccggg gagttatctc tttcttgtcg ttaagcaacg tcccatctac
     4561 gtctaagact aataatttgt acttcatggc gtcttatttt atggtttaga atacaaatgt
     4621 acataaaata gttgatagtt agaagacatt tccatgaaag gaatttacgt atatcggcgc
     4681 aagctcacgc ctatatcggt gtagccttgc ggcgatatac gtacaggctt atgccgatat
     4741 aggcattggc ctgtgccgat actggtgtaa atgtctctga aaaaacacgt acgtgttctc
     4801 gcgaaaacat gtacgtgttt ctcggaaaat acgtacgtgt ttttttcaaa gcaattcttg
     4861 gatgaaacga gccactccat cctcatcgtt cgtgtattgg gtgatgcggt cggcattggc
     4921 cttgacaggg ggctgggcgt tggccatagc gactcccaat ccggcgaaac ggatcatgga
     4981 tacatcgttg aaaccgtcgc cgatagcgat cacttcctcc tgttttatcc gggttcgctc
     5041 tagtaagcgg gataacgagg cggctttgtc gatgcctttg gggacaagct ccagatagaa
     5101 tgcctcggaa cgatatacgt tgatacgttt ccctaattct tggcggagct tctcttccaa
     5161 cggtaccaac atctccggtt cgcctaccac caagcattta tcggctggct gatgcaaatc
     5221 ccgcaggaaa tcgtcggtag ccttgatctt cattttggtt aagaaagatt cgtattgtac
     5281 gtatttattt tccgggtgtt cgcttaagat atatttaccg ttgtaggaaa ggatagccag
     5341 tcccgcttct ttggagcggt tgtataaaac aggtacgata tcgggtggca aagcctgttc
     5401 gaaaagtact ttgtctgtca tcaagtcgat caccttaccg ccgttgaagg aaaggataaa
     5461 accaccatat tgctttatgt tcagttcctc ggctaaaggc acgataccgt aggtgggccg
     5521 gccggaggct aagaccagat gcaatccttt ttcctgcgct tgcagaaggg tttccctcgt
     5581 aaacggggtg atctcttttt tactgtttgt cagtgtaccg tctaaatcca gtaccaataa
     5641 tttatagttc atgctcttgt ttcgtgttga tcgtgattat tttacctctt tgggagatat
     5701 aattatagag ttctttataa aatgcgtgcc gggtaagggt ggaagcgtct cccaagatca
     5761 tcagtttcat acgggcacgg gtgatcgcta cgttcatgcg ccgtaagtcg ttcaagaagc
     5821 ctatctttcc atcctcgttg gccctcacca aactgatcaa gatgacatcg cgttcttgcc
     5881 cttggaaacc gtctacggta tgtacggtaa tcagtctgcg taaaggcttg aagaaagcgt
     5941 cctgtttgat taatttacgg atgtattgta cctgcgcctt ataaggggag atcaatccga
     6001 agtcgatatt ctcctccagc actctctcct tggatatttt ctgtatatag gagcgtaatt
     6061 gttccacgag caattccgcc tcttgcctgt tgacacggct catggtctcc tctctcgtat
     6121 tttccgtgaa atcgcactcg gacgtatcga accatacgat gggagtgtcc agtcgcaaga
     6181 ttcctcgccc acttacctcg ggagcggatt cgagttcgtt atgatagaac cattgggagg
     6241 agaagcgcat gatatcctcg tgcatacgat attggatctt caggagagag actgtttccg
     6301 gtttcgtgtg ggctatcttt tgcatcaagg tacgtcctaa gccttctcgt tccgcttcta
     6361 tacatttaat agtagggggc aattggtgat gatcgcccgc tagtatgacc cggtccgcct
     6421 tgccgatcgc tatccagcaa gcggcttcca aggcttgggc ggcctcgtcg ataaacaagg
     6481 tcgtgaagtg ccggttcatc atgacccggt ttgcggagcc aaccaaggtg caagcaacga
     6541 cacgagcctc gtcgaacagc tctgtatcga tcttgacttc cagttcggtc gcccggaatt
     6601 tcaaacggga gaggcggttt cggatcgtat cccgttcctc ccggcttttc tttcgcatat
     6661 tggattgtat atcccgtatc gctttccgga tgctccataa ttcgggataa tccggatgcg
     6721 actcgaaacg gcgttcatat gtgaaagaga gcatcttgtc attgatacga gtggggttcc
     6781 cgatgcgcag gacgttaatg cctctatcta ccagtttctc cgagatgcag tctacggcgg
     6841 tattactttg ggcgcaaacg atcacttgat tctcccggtg aagggtctcg taaatggctt
     6901 ccaccaaggt ggttgttttc ccagttccgg gagggccgtg tacgatagat acttgtttcg
     6961 ctcccaatac cttatttacg gcttcttcct gagaacggtt caaccaaggg aagcggatcg
     7021 ggaataattc ccgctgtccc ggtttttcct gtcccagcaa tacatccctt agatgagaga
     7081 gttggttgtt ttttgcccgc atcacgtccg agagagcgga aaacatcgtt ttatagctgg
     7141 tctcgtcgaa gtagagttgc acgccgagat cattgctttt tccttgtata tccatcaagg
     7201 cggaaggagt ggggagaact accaccatcc ggtcctcttg cacgtagctg atcgtggcgg
     7261 agaaatccag atacttaaat ttaccactga tatctgccgt aaagaagcaa accgggcgcc
     7321 cgtactcaaa attatgctcg atctcccggt cttctgtcct ttcgatctcg atcaccaatt
     7381 ggtttaagga gttataataa ctgcgtcccg gagtgaccgg ataccaacag aggccctgcg
     7441 ccactcgttt tcgcaaaccc gtacgctcgg attgctgtcg gtatgtttcc ttctcatatt
     7501 catattcttt ctgcaggaga tcatattgat gttgcaaatc tacaagcggc gatgaaattc
     7561 ccattccttt atcaattcaa ttaatcggat aaatacagcc cgggcgttct aggtcccgaa
     7621 gtaggcgaca aaagtactaa aattatcgtt ccgtacccaa gttgcggtaa gtaaagaaaa
     7681 agaataccgc taacgttggt agtgtctata aaattcctaa ttttgtacga aaactaatat
     7741 cataaaaaaa tgaatgagaa cgatgctttt tataacgcat taatagatgt agctgcttgg
     7801 gataaagaga ataccttaga tcgttttatg aatagtgata gcctcttcaa aaagtttcta
     7861 tataaattta ttactacaga cggttcgtat gtgaaattac ggagctcttt agtagagcgg
     7921 gatttggaga atgccaagct atattcgcat accttgaaag ggatagccgc taatttaggt
     7981 ctggtaaatc tattcgatgt atcgaataat atactatcgc tgttaagaga agggaatctg
     8041 gaagaagcgt tgcgttatga agatgcattg ggaaaacaat acgatgcctt gcgagatatc
     8101 gttgttgagt tttgttctta atctattgta tattaactat ctaattctaa ataaagacta
     8161 tcagtatgga tactatcata aaaactcaaa ttatagattt gattcacagg gaggtaatcc
     8221 ctgctatcgg atgtacggaa cctattgccg tggctttggc ggccgcaaaa gcggcggaag
     8281 tgctggggcg taagccagag aagatagagg tttatctgag cgccaatatc ctgaagaatg
     8341 ccatgggagt aggaatcccg gggactggca tggtggggtt gcctatcgct atcgccttgg
     8401 gatcgatcat cggtaagtcc gcttatgggc tagaggtgct gaaagacttg actccggagg
     8461 gattgaaaga aggtaaggaa atggtctgca agaaatgtat cggtatagac ctgaaagaga
     8521 atgtagataa actttatatc gaaattataa gttctgcagg gaacgatcgt tcaagggtga
     8581 tcatttgcca tgagcatacc catataatat atgtagagaa aaacggggag gtattgactg
     8641 atttacgtat ggcaaacgct tctggcgagg aagtatgtga gaataaggat ttacgtcttt
     8701 ccttctctat ggtctatgag tttgccatgg aaatgccatt ggatgagatt cgttttattt
     8761 tagaaacagc tgagttgaat aagaaagccg cccaagcttc catgaaaggc aattacggac
     8821 atactgtaag caagacggtc tcgggtgctt tcggccgtaa gttcatggga gattccgctt
     8881 atacgcatat gttgatcatg acttccgccg cttgcgacgc tcgcatggac ggcgctatga
     8941 tcccggtgat gagtaattcg ggaagcggta atcaaggaat cgccgctacg cttccggttc
     9001 tttctttcgc cgaggatatc caatgctcgg aagagcaact gatccgtgcg ttgatgttaa
     9061 gccatttgat ggtgatctat atcaagcaaa gtctgggacg cttgtccgcc ctttgcggtt
     9121 gtgtggttgc cgctacggga gcgagttgcg ctatcaccta tttgatggga ggaaataagg
     9181 cgcggatttc ttatgcgatc aagaatatga tcggtaatat taccggaatg atctgtgacg
     9241 gtgccaagcc gagttgcgcg atgaaagtat ctagtggcgt atctacggcg atgctttccg
     9301 ctttgatggc catggaggat aaggtggtga cttccgtgga aggtatcatc gatgaggatg
     9361 tggataaatc gatcgcgaac ttgaccgcta tcggttctaa aggaatggag gcgacggatc
     9421 gtctggtgct ggacatcatg accggtaaat cttgttaatg ggattctatg gaggaggcac
     9481 caaaggcgag gaaaaaagag attatgcgag tgacactttt agggtcattc gctaattttg
     9541 ttttattggt attcaagttc gtggcgggta tctgggggca tagtagcgct atgatcgccg
     9601 atgcggtaca ttcgttatct gatttcgtaa cggatataat cgtacttctt tttgtcaata
     9661 tatcttccaa gccaaaggac gagagccatg attacgggca tggtaaatac gagactttgg
     9721 cgacttcaat tgttggtatc gtcttgcttt gtgtaggttt tggccttttc tgggagggag
     9781 cgaacaagat ttatgacttt tatttcaagg ggattccgtt ggaaagtccg ggaatgatcg
     9841 ctttagttgc cgctcttatc tccattgtga tcaaggaatt actgtatcat attacggttt
     9901 gggtaggaag gaagcagaat agtcaagtcg ttatcgctaa cgcttggcat catcgctcgg
     9961 atgccttttc ctcgatcggt acggctttag gtatcggagg ggcgattttg ttgggggata
    10021 attggcgtgt gctggacccg ttggcggctg tgattgtcag tttatttatc gtaaaagtag
    10081 ccttacaact agtgatcccg gcgattaatg acttattgga gaaatctttg ccgaaggagg
    10141 tggaggatga gatcttggcg atcattagtg agattcccga ggtaaagagc ccgcataatc
    10201 tacgtacccg ccgcatcggt aataattttg ctatcgaggc gcatatacgg gtggacggac
    10261 agataaccgt gactcgtgcc catgacttga cgaaagagat cgaacagaat ctgcgtgata
    10321 agttcggtca ggctacgcac atcgctttgc acgtggaacc aattaaataa acgaattgtt
    10381 atttgaccat gatgaagaac ttatataggg gagaagtgct ctatttgatc gcttccccgc
    10441 tggatcatgt ggaggcttac cgctattttg aggatggggg actggctgtt gttgatggaa
    10501 agattgtaga ggcggggccg ttcgaggcga tgcgttcccg ttacccggat ttcccggtga
    10561 cagactattc cggtaaattg attacacccg gctttattga ttcccatatc catttctccc
    10621 agtcggagat acagggaatg tatggcaagc aacttctgga ttggctggac gaatatacgt
    10681 ttcccgccga ggaagctttc tcttccatgg aatatgcaca agatatcgct cgctttttcg
    10741 tgaaggaact ggtaaagaac ggaactacga cttgtgccgc ttatgccacg gttcatcctg
    10801 cttccgtaac cgcattattt tccgtggcta cggagtataa tatgtgtatc ttggctggaa
    10861 aggtgatgat gaaccggaac gctccggatt atctgatgga taccacgcat cagggtgagt
    10921 tggactgccg tagcttaatc gaggattggg acgggaaagg acggaatcac tatgtgatca
    10981 cgccccgttt cgccataacc agtacgccgg atcaattaaa gtctgccggt cgtttacatg
    11041 ccgaatatcc cagtacctat atacagacac atctttcgga gaatctggga gagattgaat
    11101 ctgtcttatc gctctgtccc ggtcatgcgg attatctgga ggtctatgag cgtgccggat
    11161 tgttgaccga tcgttcgata ttcgggcatt gtgtccatct aaccgatcgg gaatataagc
    11221 ggttgggaga aacgggaggc attatcgccc attgcccgac ctcgaacctt ttccttggaa
    11281 gcggattatt cgatatgagg gaagcgaacc gttacggcgt acgtactacc ttggcgacag
    11341 atgtcggtgc gggtacatct ttctctatgt ggcgtacgat gggagaggcc tataaggtac
    11401 aacagttgaa cggttatccg atgacagctt tggaggctat ctataaatgt acgctaggct
    11461 ctgcacgggc cttatcgttg gacgaccgaa tcggaagttt cctccctggc cgtgaagcgg
    11521 atttcatagt cgtggattat gccgctacct ctgtccagaa attgcgtatg gagtatcttc
    11581 gttcgagaga taaatggacg attgagaata agctgtttgg cctgcaaacc ctcggcgatg
    11641 accggaatac ggtatgtact tatataatgg gcaagcaagt atacggctca gattcgtgcg
    11701 atcatcaaga agcaagtatg taatacgacc gttacgacga tccataggcg ctcggcagta
    11761 gtcgggcgca atctcgggaa atgatattct atagccccgt gcttgcaagc ggagaggcaa
    11821 tctccgcaat aggtacaggt atagccgatc tttcccttct cgatctcttc tttatgtagg
    11881 gcatcataac ggcaagcgtt tgtgcaagcc atgcaatggc aacaatccgt ggtcagtcgt
    11941 acccggaaag gagagaggta tttgaggaaa gacactaaag tcccgatcgg acaataacta
    12001 ctgcaatgca ccatcttccg tctctttctg gaaaacaata gcatgacaag taggccgata
    12061 actccgaccg ctattccaaa agcggtggct atcctgccgc tcgccccgaa tattcggagt
    12121 aggatggccc ccaacataac cagaaataat atgctgtatc gcatttgctt gtgatagggg
    12181 aacctttttc gttccaattt tccccgggca ctccatgcgt caaatgcccc gaagtaacaa
    12241 agctggctac accaagcggg accggatagt aataaggtgc tgataaaaag tatgggcatg
    12301 aataatccct cgaagcgata aagcggtccg gccaagatta ccgcggggat cggtaaatgc
    12361 agttttccgg tcataaggaa aataggatcg gcaaaaatcc ctagagcaag ttgcccgaaa
    12421 aaaacgatcg agaataacaa ccacgctcgt tttctccatt tgggacgttc ttgccgatct
    12481 tgcatcttat agcagagcca accaccgtat agcatggcaa gtatcacttg tatccatcct
    12541 ccatacggaa ataacctttc gcctatcaat agtggatttt taggcatgac ttgaacgatc
    12601 gagagaagtc ccccgactaa taatacggta ctgataacaa tacgtctcgt tttcatgctc
    12661 aattatttta tgcgtaaaag tatgcctttt acgcgaataa ttatagcacg ggcattgtat
    12721 ttctgatact tgttacaccg attaaacgat cataccgtgc tcccatcggg caataataga
    12781 cgtaaatgct atattcgttc tccgtctgga agaaattacc ctcgataggg ccggtctgtc
    12841 ctacggtctg tccgttaggg acaaagaggt actgatagtt gtaactgcct tgtttcagta
    12901 agacggattt ctcgtattga tgcgtctccg gattatagcc catcttactt ttctcgtcca
    12961 atacattatt atataattcg ccgttcaaat acacgtttcc atcgggaatt aagtccatgg
    13021 cgagggtaaa gtgaacgatg taatagtccg cttccgtatc cgggtcgtta caattactgc
    13081 aacggatgaa aaaacggccg tcttggtctt gatcgtattg atacgataat tggtcacgcc
    13141 gatagtccgt catcaactct acatggtagt atggattatg gaacgagata ctttctacgt
    13201 gcatgccatt gtatttgttg ctcaaaaatt ccatacggcg atattcgttt cctgcgggaa
    13261 agatcaagtt ctgattgttc gtataagaga tctggttttc taaaatagtc ataggctgaa
    13321 gacctgttac ggcattatcc ctgcggttat tctgataaac ccagattttc aagtcggtct
    13381 gaggataggt gatggggaaa ttcttgttat tgatcgcaaa gctgacttgt tggtgtgact
    13441 gattggtatc gatatccgta tttccgctca ccgtagcggc gacactaacc atcggctcga
    13501 aaatagaaaa gcaagcggta aatacgatct gggagggatc atcctcgtta tatacttgca
    13561 aggcataatt ccccgagacc ttcggttgaa cgtcatcgtt tgggaaaagt aatcggtagt
    13621 tggtgtattg caccgtagta cccatcgcat tggcgaaatc ctcgatcgtg ctcccttgga
    13681 aaccattcat atactcaatc ggg
//
