LOCUS       c00005_gnlPro..        14078 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MCDFJOGG_5.
ACCESSION   c00005_gnlPro..
VERSION     c00005_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 23:28:39
            Original ID  :: gnl|Prokka|MCDFJOGG_5
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 9729
            Orig. end    :: 23807
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14078
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[19729:22788]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13059
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14078
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14078
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(650..880)
                     /locus_tag="ctg5_11"
                     /transl_table=11
                     /translation="MWEKKRNLYKQLKAVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX"
     CDS             complement(905..1048)
                     /locus_tag="ctg5_12"
                     /transl_table=11
                     /translation="MRTRNEIHINELASVLEIPVHQLSMLLFELEINGKVKALPGNLYK
                     LS"
     CDS             1067..1894
                     /locus_tag="ctg5_13"
                     /transl_table=11
                     /translation="LFRGECFRFGEKQLRLNGSSPSLDIPTKSGEQIVRRSDQAGFILS
                     DQIVASFGMAVTDTPWKAIDIPAIRECNIGSYQRASFFCRFNHDRTIRDSGDNPVPPEE
                     IWTVWFCTAGKIGQQTARFQHFDSRIPMAGRIDTIQAMRQHSNSRKSVVQSVPVSTDID
                     AVSQSTHDQQVRDHFCQVFYKGFGKLPTIFGRVASTHNTDDTGRIKVSISLKIEKYRGI
                     RTFSQAHRIICISQIITGNIVFLDKSQLFFRPLQDFRAFDFGSNIAADTRDPS"
     CDS             complement(2017..2424)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_14"
                     /sec_met_domain="HBT (E-value: 2e-08, bitscore: 25.6,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 2.9e-09, bitscore: 28.5,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYIFKLTDKVRDYECDLQGVVNNSNYQHYMEHTRHEFLESLGE
                     NFGKMHEKGVDGFVSRVEIQYKTSLKSGDSYISCLNAYKKGVKLVFEQDIYRASDNALA
                     TKGIVESVIVENGKLTRGEYFDEMLKRIEHT"
     CDS             complement(2424..3695)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_15"
                     /sec_met_domain="Peptidase_U32 (E-value: 3.3e-69, bitscore:
                     223.6, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYKNLNEKDFEIMAPVGSYESLMAAIQGGADSIYFGIEGLNMRSR
                     SSNNFTTDDLRKIVALCREHGIKSYLTVNTVIYGEDLPLMREIIDAAKEAEVSAIIAAD
                     VAAMNYANSIGQEVHLSTQLNISNAEALKFYARFADVVVLARELNLKQVHEIYRQIVDQ
                     QITGPKGELIRIEMFAHGALCMAVSGKCYLSLHEMNASANRGACMQICRRAYSVKDKDS
                     NIELDIENQYIMSPKDLKTIHFMNKMMDAGVRVFKIEGRARGPEYVRLVTECYKEAVRA
                     YCNGTFDEKKVAAWDERLRSVFNRGFWDGYYLGQRLGEWSSKYGSGATKKKVYVAKGIK
                     YFDKIGVAEFEMESGNLKVGDEILITGPTTGAVMQTIEEIRVDLKPVDETVKGERFSLK
                     VNEKIRPSDRLYKMEKVQLEKVFE"
     CDS             complement(3738..4934)
                     /locus_tag="ctg5_16"
                     /transl_table=11
                     /translation="MKKMLFGLMTAIATFTGCESKQPAGELPRIDLTATSFAFDQVEIA
                     DEIESIEYVPLELTDESLIADVLDLCVSDEYIFVYSTRQDGVLQFDRKGKYLRCIAKTG
                     NGPGETGQIISLTVDEENRLFCVSEYFSTSFYSFDGEFIKKIENPRPYSYQFSVGPNTM
                     AELGRMYVPMNTPGMFSLGVFNWGTDDTIAFRHTIGDMDLMPLEETSLKGWIFSGSKDG
                     ILCYSEGIDTVWDVNARNIAPAFLINTGYSVEEEKEMRSSKTGNEAVDGKYSVFSFFET
                     PRHYFVKCFEGSNQSKFYLYGLDKATGELKRETSPLNAQELFKNNWTLAGIGFRNTKDN
                     GLPIWPYLSYPGKKQMVQFNTAVEIEYLKEKYPDLKKHLVLQQITEDSNPLITIYHLR"
     CDS             complement(5001..6095)
                     /locus_tag="ctg5_17"
                     /transl_table=11
                     /translation="LETYQQAIKLAEKEKDSTVFSLAYLEMGKIYRYQSLKQKALQSEK
                     KALSYIKSPACDSLRLELYREIGDMYTLSGQADSAFHYYEMAGCRIKQAKILQQNGSNK
                     EAETLLKTELEQTIFPKEKAEVCLALADLQITLGKLDEAEKSLSQVPPSHPHLYAALSR
                     IAQSRGDSLQADFYHKSYLHHLSVLRQEKEQNQITQLLRTSEQKEWEKRLTDSQKAQKE
                     QIYVWVTLLVSCSTGIWGYSRYRQKRNVVSLSETDFFSSEIYLRFHRKEEWKPVPKDWE
                     ELLQAFNRTYPDFRERLKRKIPKLSEQEWRMCCLIKMEVPPSTAAMLLCCTNQAISMRR
                     VRLYQKITGEKGTPELCDSFIRDF"
     CDS             6108..6308
                     /locus_tag="ctg5_18"
                     /transl_table=11
                     /translation="LQSFPIESSLSKELSGGDNLFLFGRRTGGEKANEKEYLYIVYHLN
                     PSFEGVKIIIFLSVYPLEQVL"
     CDS             complement(6348..7394)
                     /locus_tag="ctg5_19"
                     /transl_table=11
                     /translation="VKKAVGSSLYTLANSFNHSKIKKRITMMLKKKSNNWARLKLALLV
                     PVGFAALSAFARPETSPPPAATMTDNIHLSINKSTVNQETMQQDHAVFLTYKESGSEDL
                     NSIVCKTLDRIRTRVAEGQFKNALEVTVNPAFDDIPASYLETVKDVLEERDIKCKIDMT
                     VPNTIMDDVAKPYRKYDDVVYLIQNKKIVAALSISKFSANQNDPRLDKISKSASLILQP
                     ENPKVSRQEMEKLKNLLDKKGLTSEINMNIFKIGDAAAPPPPPPAGQVIFSYRDGQPDQ
                     QFVLYDRHAKPGANLGQRIDKIYKDNITKVSIKINKSTPKDLLETVKQELKKKINYPVQ
                     YEILQFVD"
     CDS             complement(7484..8116)
                     /locus_tag="ctg5_20"
                     /transl_table=11
                     /translation="MDAFLLYILKSGICLTVFYVCFKALFSNDTFFRFNRWILLVGTGV
                     CMLLPLCRIQTARPFPLSRPVSQLEIVFYEEEMKAFPVPESKEEITIPTEQRNISVPWT
                     GIIGIAFLTGSGICLTTTILSFGKMYQLTRKNRKLKQGKYTLILTPDPVSPFSWGRYIF
                     LSENDYRNHPNEILMHEKMHLRYNHSVDLIYMKRFFFCNGLILPYGY"
     CDS             complement(8130..8540)
                     /locus_tag="ctg5_21"
                     /transl_table=11
                     /translation="VLLNNIVVFVHSSNKKRIMVRLTSKEEEILGYFWAKGPLFVRELL
                     DLQEESKPHYNTLSTIVRSLEEKGYIGYKVYGNTHQYYALVSEDEYRRNSLKQVISKYY
                     DNSYTRVVSTLIEEEVLTIDELQKLIQQIKNK"
     CDS             complement(8787..8918)
                     /locus_tag="ctg5_22"
                     /transl_table=11
                     /translation="MSGFANLRGFDHCRNITAIYLYGDRTFFIRHIQLLLCFIYTAD"
     CDS             complement(8915..9091)
                     /locus_tag="ctg5_23"
                     /transl_table=11
                     /translation="LSASQPKRVFTVTGMFTALTTSRVMSSISGILRSMPAPAPLPATR
                     LTGQPKLISRMSG"
     CDS             complement(9120..9371)
                     /locus_tag="ctg5_24"
                     /transl_table=11
                     /translation="MPHFSENPGAAYAAPANHNGIHAILFETLFADFGGSHIAIADDGN
                     LYTGIVFYFTDQCPVCLSCVHLCPGTSVDGKGCDTAIL"
     CDS             complement(9650..9808)
                     /locus_tag="ctg5_25"
                     /transl_table=11
                     /translation="MKKTHCKYKVYLLNTQEFVITFYCKFATFCFKIDTVCGFTLLLYQ
                     QSIDSDT"
     CDS             complement(9805..9990)
                     /locus_tag="ctg5_26"
                     /transl_table=11
                     /translation="MYVYGKARRQWQRAFFMFVQTHKKAALPIIKVDAAFLLLSSETVS
                     RFPLCKDFVNLRSKIL"
     CDS             complement(10001..10639)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 59.4; E-value: 9.9e-19)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_27"
                     /sec_met_domain="Fer2_3 (E-value: 5e-19, bitscore: 59.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 4.9e-12, bitscore: 37.3,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5.9e-06, bitscore: 17.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDILNERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATG
                     ATTCQLYMRRFNDGETITIEPWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPD
                     ANAIPISKADADLAMDAAACIGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARR
                     AKAMVAKMDELGFGNCTNTRACEMECPKNISVSNIARLNREFISAKLQD"
     CDS             complement(10784..12316)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 46.4; E-value:
                     9.8e-15)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_28"
                     /sec_met_domain="FAD_binding_2 (E-value: 4.9e-15, bitscore:
                     46.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 2.4e-38,
                     bitscore: 122.1, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LITGKIERFAAHAVVVATGGYVNTFFLSTNAMASNGSAAWQCYKK
                     GAYFANPCMVQIHPTCVPVKGDFQSKLTLMSXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXRIWVPKKL
                     EDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDVASRAAKERCDAGFGVNSTG
                     LAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDDPYETPMMIYPALHYSMGGLWVD
                     YELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYFVLPYTIQNYLSDQIQVPRF
                     STDLPEFVEAEKAINARIAKLMNVKGKETVDSIHRKLGHIMWEHVGMARDAEGLKEAIQ
                     MLKDLKKEFWSNVFIPGEANSLNVELDKALRLADFIEIGALMAHDALDRAESCGGHFRT
                     EHQTEEGEAMRHDDKFMYVSCWEYQGEDKDPVMLKEDLNYQFVVPQTRNYKK"
     CDS             complement(12313..13059)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_29"
                     /sec_met_domain="FAD_binding_2 (E-value: 8.2e-08, bitscore:
                     22.6, seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXYRAREANVYRLAEVSNSIIDQCVAQGVPFAR
                     EYGGLLDNRSFGGAQVSRTFYARGQTGQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVV
                     KVDGRARGIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXTDVLAVLLPVI"
     CDS             13106..13345
                     /locus_tag="ctg5_30"
                     /transl_table=11
                     /translation="VCTTGRVLNTEIQYIESHFSQRGSSRSTRQTSTYYNYVQTTFVCG
                     IHQFLVIFIICPLLSQRALRNFRIYLSHNVLFSN"
     CDS             13492..13953
                     /locus_tag="ctg5_31"
                     /transl_table=11
                     /translation="VNRRPETVSQVKPQSNEPDQIQHRIHNIALEVEIDKRCTILRMNV
                     TMNTCQFGKHHVVPELSKVQNHEQDNDHTQNKHVLRSPFNTFRTSVDGITVVTASLTIL
                     QSQDNSIHEVHDYTCSQHQCTEQSIPVRTQQTANHVIRFTRKYCRNVHT"
ORIGIN
        1 accgaaacgg caacgtgaca gccttcaaaa ttccaacttt aaaagaatgc ctggaatgga
       61 gcaaaggcaa aacaatcctg aatttggata tcaaggatgt acctttagaa gttatggctg
      121 attttataga aacagaaaag cctgttaacg tcatgtacac ggtacataac gccagtcaag
      181 cccgctatta tctcgaccgg aaaccggatg cgatgttttc ttgctggtgt aagaatcggg
      241 aagaattcga taattatgaa aaagccggca tcccctggaa acaggtaatg gcttatgtag
      301 gcccgaagat gaagcctgaa cagcaaccac tgtatgacgc tctgcaccgt aacggagtca
      361 tgtgcatgat ttccgttgct ccgacacatg atcgcgcgaa aacggaaaca gagaaaaccg
      421 ccggttaccg gtcagagatc agcactcgtc ccgacgtgat cgaaacggac tatccgtacc
      481 tgtttcaagg actcgattta acaaaataac gcagtttaaa ggactcttta tagccgatta
      541 aaatcttttt gctatttatg ctcatctgat taacaagtat tagcaacaaa atgcttgaca
      601 aacgctcttg acgagagtat ctttgcaatg tggttttttc ataatagtat tannnnnnnn
      661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnacag
      841 cctttaattg tttatagagg ttccgtttct tctcccacat acaaatcgta tacgaaaaag
      901 ccggtcagga cagcttatag agatttcccg gcaacgcttt taccttcccg tttatttcca
      961 gttcgaacaa tagcatagag agttgatgta ccggtatctc caacactgag gcaagctcgt
     1021 tgatatgaat ctcattccgc gttcgcataa tggctaaaac cggattttgt tccgaggtga
     1081 atgtttccgc ttcggcgaaa aacaactccg tttgaacggg agtagcccca gcttggatat
     1141 cccaacaaag agcggagagc agatcgtccg cagaagtgat caggccggct ttattttgtc
     1201 ggatcaaatt gttgcatcct ttggaatggc tgtcaccgac acgccctgga aagctataga
     1261 catcccggcc ataagagaat gcaatatcgg cagttaccaa agagcctcct ttttctgccg
     1321 attcaaccac gatcgtacaa tccgagattc cggcgacaat ccggttcctc cggaggaaat
     1381 ttggacggtc tggttctgta ccgctgggaa aatcggtcaa cagaccgccc gattccagca
     1441 tttcgacagc cgtattccga tggcaggaag gatagatacg atccaagcca tgcgccagca
     1501 cagcaacagt cggaagtcgg ttgtacaaag cgttccggtg agcacagata tcgatgccgt
     1561 aagccaatcc actcacgacc aacaagtccg ggatcacttt tgccaagtct tttataaggg
     1621 attcggtaag ctcccgacca tattcggtcg cgttgcgagt acccacaata ctgatgatac
     1681 gggtcgcatc aaggttagta tttcccttaa aatagaaaag tataggggca tccggacatt
     1741 ctctcaagcg caccggataa tctgtatcag tcagataata acaggaaata ttgtttttct
     1801 cgataaaagc caactctttt tccgcccgtt gcaagatttc cgggcgtttg atttcggcag
     1861 caatattgct gccgatacca gggatccttc ctaacaactg ttgcttttca gtaaacacag
     1921 cctctgcttc tcccaaagcc tgcaggagat gacgcgccag gatatctccc acgccgttta
     1981 tcatagtaag gccgatttgg taaatccgtt tgtcagtcat gtatgttcta ttctttttag
     2041 catttcgtcg aaatattcac cgcgtgtcaa ctttccgttc tcaacgataa ccgactcgac
     2101 gattcctttc gtcgccaatg cattgtcaga agccctatat atatcctgct cgaatacgag
     2161 cttgactcct tttttatagg cattgaggca agagatatag ctgtcgccgc tcttgagcga
     2221 ggtcttatac tggatttcta cccgcgatac aaatccgtca accccttttt cgtgcatctt
     2281 tccgaagttc tcgccaagcg actccaagaa ttcatgccga gtatgttcca tataatgctg
     2341 ataattggag ttgttgacca ctccttgcag gtcgcattcg tagtcacgga ccttgtctgt
     2401 cagtttaaaa atatactctt tcattattca aatacctttt caagttgaac cttttccatt
     2461 ttatacaatc ggtcagacgg ccgaatcttc tcgttcacct tgagagagaa ccgttcacct
     2521 ttaacggtct cgtccaccgg cttcaagtcc acacggattt cttctatcgt ctgcataacc
     2581 gcacccgttg tcggtccggt aatcaggatc tcatcaccca ctttcaggtt accggattcc
     2641 atttcgaact ccgccacgcc gatcttgtcg aaatatttga ttcctttggc aacatacact
     2701 ttcttcttag tcgcgccgga gccatatttg ctactccact cacccaaccg ttgccccaaa
     2761 taatagccat cccagaatcc tcggttgaac acactgcgca ggcgttcgtc ccaagcggca
     2821 actttctttt catcgaacgt gccattgcaa taggcacgca cagcttcctt atagcattcg
     2881 gtcaccaggc ggacatattc gggaccgcgg gcacgtcctt cgatcttgaa tacccgtaca
     2941 cctgcatcca tcatcttatt catgaaatga attgtcttaa ggtctttagg cgacataata
     3001 tactggtttt cgatatccag ttcgatattg ctgtctttat cttttaccga ataagcacgc
     3061 cgacaaatct gcatgcaagc tccccggttg gcggaagcgt tcatttcgtg caggctcagg
     3121 taacatttac cggaaacggc catacagaga gctccgtggg caaacatttc gatacggatc
     3181 agttctcctt tcggtcccgt aatctgctgg tcgacgatct gccgatagat ttcatgcacc
     3241 tgtttcaaat tcagctcacg cgccaagacg acaacatcag caaaacgggc atagaatttc
     3301 agtgcttccg cattggaaat gttgagctgt gtggaaagat gcacctcctg tccgatgctg
     3361 ttggcatagt tcatagctgc cacatcggcc gcaatgatcg ctgaaacttc cgcctccttc
     3421 gccgcatcga taatctcgcg catcagaggc aggtcttccc cataaataac cgtattgacg
     3481 gtcaaatagc tcttaatacc gtgctcacga caaagcgcaa cgatcttgcg caaatcgtct
     3541 gtcgtaaagt tattggaaga gcgcgaacgc atattcaatc cttcgatacc gaaatagata
     3601 gaatcggctc ccccttggat agccgccatc agtgattcgt acgaaccgac aggcgccatt
     3661 atttcaaaat ctttctcgtt caagttctta tacatttact ggttcgttcg caaaggtagg
     3721 aataatatcc gagaagatca gcgcaaatga taaatcgtga tgagcggatt tgaatcttcc
     3781 gttatctgtt gcaggaccag atgcttcttg agatcaggat atttctcttt gagatattcg
     3841 atttccacgg ctgtattaaa ctgtaccatt tgttttttgc cgggataaga caggtaaggc
     3901 cagataggaa gaccgttgtc tttcgtattt cggaagccta ttcctgccag cgtccagttg
     3961 tttttgaata attcctgggc attaagcgga gaagtttcac gtttcaactc accggtagcc
     4021 ttatccaagc cgtacaaata gaatttggat tggttggaac cttcgaaaca tttaacgaag
     4081 taatgccggg gtgtctcaaa gaagctgaag acgctatatt tcccgtctac cgcctcatta
     4141 ccggttttgg aagagcgcat ttctttttct tcctcgacag aatatcccgt gttgataaga
     4201 aaagccggag cgatatttct tgcatttaca tcccagaccg tgtctatccc ttccgaatag
     4261 catagtatgc cgtccttact gccgctgaat atccaacctt tcaggctcgt ttcttccaac
     4321 ggcatcagat ccatatcccc gatcgtatgc cggaatgcga tcgtatcgtc tgtgccccaa
     4381 ttaaagactc cgagactgaa catgcccggc gtgttcatgg gaacatacat cctccctaat
     4441 tccgccatcg tattcgggcc aacagagaat tggtacgagt aagggcgcgg attctctatc
     4501 tttttgataa attctccatc aaaggagtag aaagaggtgg agaagtattc gctgacacag
     4561 aagaggcggt tctcttcgtc tacggttagc gaaatgatct gtccggtttc tcccggcccg
     4621 tttcctgttt tagcgatgca gcgcaagtac ttccctttcc ggtcgaactg caagacaccg
     4681 tcctgacggg tagaatagac gaagatatat tcgtctgaaa cacacagatc caatacgtct
     4741 gcgatcaggg attcatccgt tagttccaac ggaacatatt cgatggattc gatttcgtct
     4801 gcaatctcta cttgatcgaa agcaaaactt gttgctgtca gatcgatccg ggggagttct
     4861 ccggcgggtt gtttggattc gcatccggta aaagtggcaa tggctgtcat aagcccgaac
     4921 aacatctttt tcatacgctt tttttagaca aaagtagaag atacggctat ttccccggtt
     4981 tcacatcagt tcacatctgc ttaaaaatca cgaataaagg aatcacacag ctcaggagtg
     5041 cccttttcac ctgtgatttt ctggtacagg cgtacgcggc gcatcgaaat cgcctggttc
     5101 gtgcagcaaa ggagcatggc ggcagtagaa gggggaactt ccattttgat caggcagcac
     5161 atgcgccatt cctgttcgct caactttggt attttccttt tcagccgttc ccggaaatcc
     5221 ggataggtcc ggttgaaagc ttgcaacaat tcttcccagt ctttgggaac cggtttccat
     5281 tcttcttttc ggtggaagcg caggtagatt tctgaagaaa agaaatctgt ttcggacagg
     5341 gaaacgacat ttcttttctg ccggtagcgg gaatatcccc agattccggt actgcaagag
     5401 acaagtagcg tgacccagac atatatttgt tctttttgtg ccttttggct atcggttaaa
     5461 cgtttttccc attctttctg ttccgaggta cgaaggagtt gggtaatttg attttgttct
     5521 ttttcctgtc gcaggacgga taagtgatgg aggtagcttt tgtggtagaa atcagcttgc
     5581 aggctgtctc cacggctttg ggcgatgcgg gacagggcag catacagatg cgggtgggaa
     5641 ggggggacct gacttaaact cttttcggct tcgtccaatt ttcccaaagt aatctgcaaa
     5701 tcagccaaag ccagacatac ttctgctttc tctttcggga aaatcgtttg ttccaactcc
     5761 gtttttaata aagtttcagc ctctttattg cttccattct gttgcaatat ctttgcctgt
     5821 tttatccgac atccagccat ttcataatag tgaaaggcac tgtctgcttg tccggacaag
     5881 gtatacatat cccctatttc ccggtaaagt tccagccgta gcgaatcgca ggcaggactt
     5941 ttgatatagc ttaatgcttt tttctcactt tgtagtgcct tttgttttaa agattgatac
     6001 cgatagattt ttcccatttc caggtaggca agggaaaaga cggtgctgtc tttctccttc
     6061 tccgccaatt tgattgcctg ttgataggtt tccaatgccg gaagaaattg caatctttcc
     6121 ccatagaaag cagcctgtcg aaggagctct ccggcggtga caatctcttt ttgttcggta
     6181 gaagaacagg cggtgaaaaa gcaaatgaaa aagagtatct ttacattgtg tatcatctga
     6241 atccttcttt tgaaggagta aagataataa tattcctctc cgtttacccc ctggagcagg
     6301 ttttgtaaac ggagaggatg ataaatagat aatccgtgtt tctgatttta atcgacgaat
     6361 tgcaggatct cgtattggac agggtaattg attttctttt tcagttcttg cttaaccgtt
     6421 tccaacaggt ctttgggagt acttttgtta atctttatac ttactttcgt aatattgtcc
     6481 ttgtaaatct tgtctatgcg ttgtccgaga ttggctcccg gtttggcatg gcgatcgtat
     6541 aaaacgaact gttggtccgg ctgcccgtcc cggtaactga aaataacctg tccggcagga
     6601 ggtgggggag gtggagccgc agcatctccg atcttgaaaa tattcatgtt gatttcgctt
     6661 gtcaatcctt ttttgtccaa caagtttttt aatttctcca tttcttgtct ggatactttc
     6721 ggattttcag gttggagaat taaggaagct gatttggata tcttatccag cctcggatca
     6781 ttctggtttg cactaaactt actgatgctt agtgctgcga caatcttttt attctgaatc
     6841 agataaacca catcgtcata tttgcggtaa ggtttggcaa catcatccat gatagtattc
     6901 ggaacagtca tgtcgatctt gcatttaata tctctttctt ccaaaacatc ttttactgtt
     6961 tccagataag aagccgggat atcgtcgaag gccggattaa cagtaacttc cagggcgttc
     7021 ttgaattgtc cctccgctac tcgtgttctg attctgtcca gagttttgca tacaatactg
     7081 ttcagatcct ccgaacccga ttctttgtag gtgaggaaaa ctgcatgatc ctgttgcatc
     7141 gtttcctgat ttaccgtact tttgttaatc gatagatgaa tgttgtcggt cattgtcgct
     7201 gccggcggcg gacttgtttc cggacgggcg aatgcactta aggccgcgaa gcctaccggg
     7261 accaggagcg caagcttcaa ccgggcccaa ttgtttgatt tcttttttaa catcatagta
     7321 atacgttttt taattttact gtgattgaag ctgttggcaa gagtgtagag gctggagccg
     7381 acagcttttt tcacgagtaa tagttgatat tttgttgcat cgatgccttg actgagtacg
     7441 cctttatccg cctggtattc gtgtatgccc cgtaattccc tttttaataa ccatacggca
     7501 ggattaaacc attgcagaag aagaatcgtt tcatatagat cagatcgacc gaatggttat
     7561 agcggaggtg cattttttcg tgcatgagga tttcgttcgg atggttccgg taatcgtttt
     7621 ccgaaaggaa tatataacgt ccccaactga aaggggatac gggatcggga gtcaggatta
     7681 acgtgtattt cccctgtttt agtttcctgt tttttcttgt tagttgatac atttttccga
     7741 atgacagaat cgttgtggtc aggcagatac cactgcctgt tagaaaagca atcccgataa
     7801 ttcccgtcca gggaacagat atatttctct gctctgtcgg aatcgtaatt tcttctttgc
     7861 tttccggaac aggaaacgct ttcatctctt cttcatagaa aactatctcc agttggctga
     7921 ctggccggct aagaggaaaa ggccgggctg tttggatccg gcaaagtggc agcaacatgc
     7981 aaactcctgt ccctaccagt aatatccagc ggttgaaccg gaaaaacgtg tcgttactga
     8041 ataatgcctt gaaacagaca taaaagactg tcaggcaaat accagatttt aatatgtata
     8101 gaagaaaagc gtccataagc gttggttttt tatttgtttt ttatctgctg gatcagcttc
     8161 tgtaactcgt cgatcgtgag cacctcttct tctatcagcg tcgaaacgac acgggtgtac
     8221 gagttgtcat aatatttgct gatcacctgt ttcaaggaat tacgccggta ttcgtcttcc
     8281 gataccagtg catagtattg gtgcgtatta ccgtatacct tgtatccgat atatcctttt
     8341 tcttccaatg agcggacaat cgtggacaag gtgttataat gcggcttaga ttcttcctgt
     8401 aagtcgagta gttcgcgaac gaacaggggg cctttcgccc aaaagtagcc caatatttct
     8461 tcttcttttg atgttaatct aaccataatc cgttttttgt tagaggaatg cacaaataca
     8521 actatattat ttagtaacac aactatatca tatagttatt ttactatatt ttttagtaga
     8581 tatcctttta tccctgtttt tagcaggaaa tcagtacctt tgtccccgtc attgataata
     8641 taaatatgaa aataggtaca atagatttag gcgaacgccc cgtcttctta gctccgatgg
     8701 aagacgttac agatatttct ttccggttga tgtgcaaacg ttttggtgcc gatatggttt
     8761 ataccgaatt cgtttcagca gacgccctaa tccgcagtgt aaataaaaca cagcaaaagc
     8821 tgaatgtggc ggatgaagaa cgtccggtcg ccatacaaat atatggccgt gatgttccga
     8881 caatggtcga agccgcgcaa atttgcgaag ccgctcatcc ggacattctc gatatcaatt
     8941 tcggttgccc tgtcaaacga gtggcaggca aaggagcagg cgccggcatg ctgcgcaata
     9001 ttccactgat gctggacatc acccgtgaag tcgtcaaagc ggtgaacatc cctgtcaccg
     9061 taaaaacccg cttgggctgg gatgccgaca accggatcat cgtagacttg gccgaacagc
     9121 tacaggattg cggtatcgca gccctttcca tccacggacg tacccgggca cagatgtaca
     9181 caggagaggc agactggaca ctgatcggtg aagtaaaaaa caatccccgt atacaaattc
     9241 ccatcatcgg caatggcgat gtgacttccg ccgaaatctg caaacaacgt ttcgaacaat
     9301 atggcgtgga tgccgttatg attggccggg gcagcatagg ccgcccctgg attttcagag
     9361 aagtgaggca ttatctggat acaggcgaga cattgcctgc cgaatctttt tcatggtatc
     9421 tggacatact gaaaaagcag gtggaacaaa gcgtggaacg tttggatgag cgccggggaa
     9481 ttctccacat tcgccgccat ttggctgcaa ctccgctgtt taaaggtatt gcagacttca
     9541 agcagacacg cgtcgccatg ctacgtgcgg aaacagtgga agcattattc gacattctgg
     9601 attccatccc cgacaaattt catacaggat acggatttca aagcgactct caagtgtcag
     9661 aatcgatcga ttgttgatat aataacagtg tgaatccgca cacagtgtca attttaaaac
     9721 aaaaagtagc aaatttgcaa taaaatgtaa ttacaaactc ttgcgtattc agtaaatata
     9781 ctttatattt gcagtgagtt tttttcatag tattttagat ctaaggttaa caaagtcttt
     9841 gcagagaggg aatcgagaga ctgtttcact ggaaagcaac aaaaaagccg catccacttt
     9901 tattataggg agtgcggctt ttttgtgggt ttgaacgaac ataaagaaag cccgttgcca
     9961 ttggcgacgg gcttttccat atacatacat atataatgta ttagtcttgt aacttagcag
    10021 agatgaactc gcggttcaag cgagcgatgt tgctaacgga gatgttcttc ggacattcca
    10081 tttcgcaagc gcgagtgttc gtacagttac caaagcccag ttcatccatc ttagcaacca
    10141 ttgcttttgc acgacgagca gcttccacct taccctgagg caaaagagcc agctggctaa
    10201 cctttgcaga gacgaacagc atagctgaac cgttcttaca agcagcagca caagcaccgc
    10261 agccgataca agcagcagca tccatagcca aatccgcatc agccttagaa ataggaattg
    10321 cattagcatc aggaacccca cctgtgttta cagaaacgaa accacctgcc tggataatct
    10381 tatcataagc ataacggtct accatcaagt cgcggattac cgggaaacca gcagaacgcc
    10441 acggctcgat cgtaatcgtc tcaccatcat tgaaacggcg catatagagc tgacaggttg
    10501 ttgcacctgt tgccggtccg tgcggatgtc cgtttacata caatgaacac ataccgcaga
    10561 taccttcacg gcagtcgtgg tcgaatacga taggttcttt gccttcgcta accaaacgtt
    10621 cattcaaaat gtctaacatt tccaagaaag aaacactctg attgattttg tcgatttggt
    10681 aagtctcaaa ctgtccttta tctttcggac ctttctgacg ccaaacttta agtgttacct
    10741 ttatatcttt atccatgatt ctaatttttg tgattgatga ttattacttc ttgtagttac
    10801 gtgtttgagg aacaacgaac tgatagttca aatcttcctt cagcataacc gggtctttgt
    10861 cttcaccctg gtattcccaa caagagacgt acatgaactt atcgtcatga cgcatagctt
    10921 cgccttcttc ggtctgatgt tccgtacgga agtgaccacc acaagattct gcacggtcta
    10981 acgcatcgtg tgccatcaac gcaccgattt cgataaagtc agccaaacgc aatgccttgt
    11041 ccaattccac gttcaagcta ttggcctcac ccggaatgaa tacattgctc cagaattcct
    11101 tcttcaggtc tttcaacatt tggatagctt ctttcaagcc ttccgcgtcg cgtgccatac
    11161 cgacgtgttc ccacatgata tgtcccagct tacggtggat agaatcgact gtttctttac
    11221 ccttcacgtt catcaacttc gcgatacggg cgttaatagc cttttctgct tccacaaatt
    11281 caggcaggtc agtgctaaag cgcggaacct ggatctggtc agacagatag ttctggatcg
    11341 tgtaaggcaa tacgaagtaa ccatcggcca atccctgcat caaagcagaa gcacccagac
    11401 ggttagcgcc gtggtcagag aagttggctt caccaattgc gaacagcccc ggaatagaag
    11461 tcatcaattc atagtctacc cacaaaccac ccattgagta gtgcaatgca ggataaatca
    11521 tcatcggagt ttcgtacgga tcatcgttcg tgatctcttc gtacatatcg aacaggttac
    11581 catatttctg tttaaccact tccttaccca gacggttgat agcatcggag aaatccagga
    11641 atacagccaa gcccgtgcta tttacaccga aaccggcatc acaacgttct ttagcggcac
    11701 gtgaagccac gtcacgagga accaagttac cgaatgccgg ataacgacgt tccagatagt
    11761 agtcgcgatc tgcttcagga atatcctttc ccttttttgt tccggcctgc aatgccttcg
    11821 catcttccag cttcttcgga acccagatac gnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11941 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12001 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12061 nnnnnnnnnn nnnnnnnnnn nnnnnnnnng acatcaaagt cagcttagac tggaagtcac
    12121 ctttcaccgg cacacaagtc gggtggatct gcaccataca aggattagca aagtaagccc
    12181 ctttcttgta gcactgccat gcagcagaac cgttagacgc catcgcgtta gtagacaaga
    12241 agaatgtatt tacataacca cctgtcgcaa caacgactgc gtgagcggca aaacgttcga
    12301 tcttaccggt aatcaaatta cgggcaataa taccgcgagc acgtccgtca nnnnnnnnnn
    12361 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12541 nnnaataccg cgagcacgtc cgtcaacctt cacaacatcc agcatttcat ggcgtgtgta
    12601 catcttcacc tttcccaaac caatctgacg actcaatgca gagtaagcac ccaacagcag
    12661 ctgctgtccg gtctgaccac gagcatagaa cgtacgggat acctgagcac ccccgaatga
    12721 gcggttatcc aacagaccac catattcgcg agcgaatggt acaccctgtg ctacgcactg
    12781 gtcgataata gagtttgaca cttcagccaa acgatagacg tttgcttcgc gggcacggta
    12841 gnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12901 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    13021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn naccatcatt ctgataattc tttgccgcat
    13081 tgataccgcc ctgtgcagcg atagagtgtg cacgacgggg agagtcctga atacagaaat
    13141 tcaatacatt gaatcccatt tcagccagag aggcagcagc agaagcaccc gccagaccag
    13201 tacctactac aattatgtcc aaacgacgtt tgtttgcggg attcaccaat ttctggtgat
    13261 ttttataatt tgtccacttc tcagccaacg ggccttgagg aattttagaa tctatttgag
    13321 tcataatgtt ttattttcaa attgaaaaaa taatatccga aattaagcac ctacaccgtt
    13381 caggtagaag ataactgtga taacagcgaa taagccacaa ataatagtgg caacccattt
    13441 agagatacat tcccaacggc ttaaccaaac ggtattgttc cagccaattg tgtgaatcgc
    13501 agaccagaaa ccgtgagtca ggtgaaacca cagagcaacg aaccagatca gatacaacac
    13561 cgtattcaca acattgccct ggaagtagaa attgataaac gctgcaccat cctgcggatg
    13621 aatgtcacca tgaatacctg ccagttcggc aaacatcatg ttgtaccaga actgagtaaa
    13681 gtgcagaacc atgaacagga taacgatcac acccaaaaca aacatgttct gagaagccca
    13741 ttcaacacct ttcggacgag cgttgatggc ataacggtcg ttaccgcgag ccttacgatt
    13801 ctgcagagtc aagataatag catacacgaa gtgcacgact acacctgcag ccaacaccaa
    13861 tgtaccgagc aaagcatacc agttagaacc cagcaaaccg caaatcacgt tatacgcttc
    13921 accagaaaat actgccgcaa tgttcataca taagtggaac accaagaaca gaatgagaaa
    13981 aagacctgat atactcatta tcagcttctt cccgatagaa gaattaagta accacataag
    14041 ataataattt aagttattta attgtattta gaaatttc
//
