LOCUS       c00038_gnlPro..        16592 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JJDPJPAG_38.
ACCESSION   c00038_gnlPro..
VERSION     c00038_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 20:36:54
            Original ID  :: gnl|Prokka|JJDPJPAG_38
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16592
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16592
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3121:6592]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3122..6592
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..16592
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16592
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(222..1454)
                     /locus_tag="ctg38_1"
                     /transl_table=11
                     /translation="MKILLVTRGSQGDVLPYLAIAAELERRGHEVTINLPQIFEETVKP
                     YGFKYVLQQFDDIGGMIDSAAQNSHKFRPFLKWMRNVIDKQFDQLIPLLKEHDILVSTN
                     SEFAVASIAEYCKKPLIRTAYAPFLPGKKIPPAVLPFPKPNPIITPAILWKLMNRMTNF
                     MVKDTINKNRAKYGLAPIRNFGYHAGERSYNYLLFSQHLGNVDPDWTFEWSIGGYCFND
                     TFQYDEKAYEEMISFVDSAQSPIIFFTLGSCSSKDGNRFSKALVDICKKHDYRLIIGSG
                     WAKTGITLQADKHLFLMKQPVPHNLIFPHCDGVIHHGGCGTTHSVGRAGKPQLITPLII
                     DQPYWSYRIHQLGLGPEGVKIAKASEQEIERKVCDLVTNPLYKKNAAHIGEMIQKEGGI
                     KNICDSIERFQ"
     CDS             complement(1488..2699)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_2"
                     /sec_met_domain="Radical_SAM (E-value: 7.6e-16, bitscore:
                     50.9, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKRTTSSFRAMSTERKLESIFLFVTGRCNAKCAMCFYAQEMDK
                     KQPDLTFDEIKKISETVGQFNRLWISGGEPTLREDLPEILELFYKNNHIKDVNIPTNGL
                     KPDRIVEWVKRFRQNCPDCNINVSLSLDGFGTTHDTQRGVQGNFYKALETLRKIQENFG
                     DDGKVLKNIATVITKYNIDQVEDFMTWVYGRFRTSTHTIEAARGMTRDDGVKILTESTL
                     RKIQDDISPIYSAYADRMVADTTGLRRPITRFFYLGLIRTLYNVRASNIDHPTPWGMDC
                     TAGETTLVIDYDGRFRACELREPLGNIKEYGCDISKVMNSEAMKLEIAAIGHGYKANCW
                     CTHGCWITSSVIFNPRKMIRSVYKGYRETKRLNHPLAINEQKLQTMEAKYHLDIERLRQ
                     LNIR"
     CDS             complement(3122..3877)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_3"
                     /sec_met_domain="Fer2_3 (E-value: 6.7e-26, bitscore: 82.5,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 1.3e-11, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.4e-05, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDISVTLKVWRQRGPKEKGQFETYKIEKINQSVSFLEMLDILN
                     EQLVNEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFHDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFTSVNTGGVPDANAIPIPKKDADLAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFICAKLQD"
     CDS             complement(3908..5851)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.5; E-value:
                     1.1e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_4"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.1e-59, bitscore:
                     194.5, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 5e-38, bitscore:
                     122.0, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEINSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDVIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERYAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDFQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDNPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFVEAEKAIKDRIQKLMNVKGKETVDTIHRKLGHI
                     MWEHIGMARDAKGLQEAIQMLKDLKKEFWSNVFIPGNADNLNTELEKALRVADFIEIGT
                     LMAHDALDRAESCGGHFRTEHQTEEGEALRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     EFVVPQTRNYKK"
     CDS             complement(5900..6592)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_5"
                     /sec_met_domain="SucD_FumR (E-value: 6.1e-74, bitscore:
                     239.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLVLFLLFHLSMNVTAVFSGEAYNMV
                     CSLLGSNWYAVAATLVLAAGVVIHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGLIVILFMLLHFSQFWYKMMFAELIGHHEVALGSAMVSPQDGAAFINYYFQGNAV
                     ITVLYLIWYVALWFHLTHGFWSAIQTIGWNNTIWMNRWECISKIVATVICGLFAIITII
                     FFLNGVGA"
     CDS             6715..8193
                     /locus_tag="ctg38_6"
                     /transl_table=11
                     /translation="MGEVRACVPTHGIMRKEKAFLMNNLYTFAYMRKDLNGPRHFSIGI
                     KFTILLFTIVILVLVLFSYRSDKHGNLFWQVEKLIPHHPDSALVLLEKVRDINGLSLRE
                     KARYCLLWTESRDEAGLRHTSDSIISIATDYYRTTRGCYWPPKAWFYRGKVYEDMDQPS
                     LALECYLRALEYEGGNWDYEFWGRLYNQIGRLYAEQELYGKAMSFLRKASAQYQLLNDT
                     AGQGRILEEVKKYEALRDSIGSLSARESIYQITSRYDVRPVREDLYRKELMLSQRGQER
                     YLYAFIIGIILFICFLLYRRWRNTQENALRREEALRRSIASQQQRMREEKEGNERQIAL
                     LEKRITKIKEEKDQELMLVSLQLEKQRLEICNESIHNKESKHLLSVAILRKSEVYEKFH
                     DRDAGKIISEDWELLEVLLNKAYDDFTLRLKKLYPAISDTELKVCMLTKIGVPANQITR
                     VLKYNSSVLRPRLFRKIFKKEGSTETFVEFISSF"
     CDS             8297..9526
                     /locus_tag="ctg38_7"
                     /transl_table=11
                     /translation="MVMKSVKLASILFYLNSVFVVSCFASCGSSPTEASSLLTADIRGG
                     MDKPGLLGLGDEIKGVTFVPLEVTTDDASLIDGVYDYAVTDRYIYVLPVKEPRIVLFDR
                     QGRFIRTLVKEGQGPGEFRGILPCIQVDERNDRLFLFSNNRVWEYTLEGEFIGQSTHEY
                     SVIYMRHIGKDRFAAISFPFQPFNGGGFGLGLFSRKGDTIAIKNDFYSFLLPHEKSGFT
                     TSIAPAYSDAQNSVLFKTGSNDTVFCISADRISAACVLDLKNSDAEVIRSLDVTDMSNL
                     RIEKKDPKDIFVQDMIEFPGHYYFRLLYNQGYYIASVDKKTGKTLVEKCVMPGSIYELA
                     DANLQHGMQGTRSYRNFPVWGRVIKDELVQVVTPYELNLYKSLRSITIPQELDLKGEEG
                     NPVFVFYSLI"
     CDS             9937..10428
                     /locus_tag="ctg38_8"
                     /transl_table=11
                     /translation="MKKAIMNTMIILFALAMCVGCGQSSEQKEESVPTDVTKAEKQEQV
                     QVEAEDEDTLENGEQVFRVVEVMPKFPGGDAELLKFIAKNVKYPQESQDKGEQGRVICS
                     FVVTKDGTLTNYKVLRGISPALDQEAVRVLQMMPRWTPGTQRGEPVAVKYTVPITFKLQ
                     "
     CDS             10544..10906
                     /locus_tag="ctg38_9"
                     /transl_table=11
                     /translation="MEKLTMQEEEAMRWIWRIGPCFVKDVLAKYEDPKPPYTTLASVIK
                     NLERKKYVKAKRYGNTYEYRPLIEETEYKRTFLGGVVTNYFANSYKEMVSFFAKDQKIS
                     TDDLKDIIDLIEKGKE"
     CDS             10924..12747
                     /locus_tag="ctg38_10"
                     /transl_table=11
                     /translation="MTPEFAYLLKVNVAFVLFYAFYRLFFYKDTFFKLRRAILLAFFGL
                     ALFYPLLNIQDWVRQQEPIADVIYMYSAMLPEATAKADAAASVDWYGWLLGSLGFIYWG
                     IVAFLCGRFLVQLSSILWLVHTSERVVIHETPVYALRKAAGPFSFFRMVFLHPESHSDK
                     ETDEILTHECTHVSQWHSIDVILSEMMCMACWFNPFVWLLKREVRHNLEYLADNTVIQS
                     GYDSKSYQYHLLGLAHHQSVTTLYNSFNVLHLKNRIMMMNKKRSPGIVRTKYLIFIPLV
                     GILMLLSNIEAVARLTVRLANEATVSNAVVTATGILVDETGQPLIGASVVVKGGKEGTI
                     TDRKGAFSLEVPANAILRCSYQGRESQEVLAADMTNNTHLSLSSKSREMNEQVFTVVEK
                     MPSFPGGDAELLKYIATNIKYPKESQDNGEQGRVICSFIVGRDGSVNNPEVLRGVTPLL
                     NEEAVRVINTMPRWNPGMQRGKAVAVKYTVPITFRLKSPVEEMKEETLTVVDVMPQYPG
                     GDRELLKFIAQSIKYPTDAQEAGVQGRVICSFVVDKKGNIVEPKIIRGIDPSLDAEALR
                     VIGMMPRWTPGRQDGKAVRVLYTVPITFRLQ"
     CDS             12804..14666
                     /locus_tag="ctg38_11"
                     /transl_table=11
                     /translation="MNAKCNLVTVLLLCCLIFPGNAQEFNWQDLVNRKQYAAVIAHADS
                     LTLADSSNYEIMNAIGQAYEGMLRYQKAYDYYRLCFSMDTTNLDILNILARTATNLGRA
                     EDAERYFHQVLSADSSNFYANYQLARLYFQLGEYEKAVDAYEKLQAQNEDNTVLYRAIG
                     DCYTRMEQYPSATTAYFQAYNLNRENAGLAVALVNSLYRMGASSPDYISEGIAICDTAL
                     FYNPGNRQLLRSKGLGLYIVKQFVQADSVYSSLLADGDSTYLTLKYGGASKYYAGLYMP
                     SVDILDMAYEQDTTSVEVCLLLGSALGKTYDRKRAYDLFDRAEKGLEPNRFLVNQLLAF
                     RAETYQKDGRYKEASRLYYEAWKKNPERLDFLAAISHMYSEIDVSKFQSEEDRQRGLFI
                     LVLYMNESLKKKADERTMVFSRALLQSFYEDMFFRNVAEETMIDPDGKKSKISIVDLRN
                     LINQLPEESEMVMEIRAMSARSSGKIEEAARLLYRAWEVKGTRVELLREIANLYSHPDI
                     SGFKNAEELQRGVFAQVTYAKELLKNESDLSNLTFTRPFLESLNSDMSKRGITEQTMLA
                     PDNRKSQLSINELQSLIQQLPETSDEVKEMIRMMNKEKALKSKK"
     CDS             14699..15856
                     /locus_tag="ctg38_12"
                     /transl_table=11
                     /translation="MRKLTTNAVAMLLALVGCMGCGNRSASSVDNLIRVDVMADYPEKE
                     LILQDLMDVEYIALETTDDFITKGAVKAIGKDIMLVTNRGSDGDILVFDRNGKGLRKIN
                     RLGQSGEEYTQLTGLVLDEGNDEIFVKDNPARKIGVYDLLGNYKRSFKFTDTSYYNYIF
                     NYDRDHLICYKSYPSEKGKRECHLIISKQDGRIIHEIQIPSKGTETPVVTEGEFIITPE
                     FYLTFPDRDKWILVNTSSDTIFHYLPDGNLSPFIVRSPSISSMDTKVFLFPTVITDRYC
                     FMRTMRKEVDFTTFKGFLGEYLVYDKQENALFSYILYNDDFINKEEVSLTSEPRNPEIA
                     ICQTLDAPDLVEAYEKGQLKGKLKEIAANLDEESNPVVMLLKKKK"
ORIGIN
        1 cccaggttta tcgggtgagc cgggctttgc gggaagcaga ccttataaaa caattaaagc
       61 ctgtctcacg acaagcccta accaaacttt gttaacctta aatctaatac tattatgaaa
      121 aaaccactat gcaaatatac ggagttaccg ctatttgtca atagtttaag tgctaaattg
      181 tgttttgtaa catgtaataa aatctaatag gaacttatgc ctcattgaaa tctttcgata
      241 gagtcgcata tattctttat acctccctct ttttggatca tctcgcctat atgagcggca
      301 tttttcttat aaagcggatt ggtgaccaga tcacaaacct tgcgttcgat ctcctgctcg
      361 ctcgctttcg ctatcttaac cccttccggc cctaacccta attggtggat tcgataggac
      421 caatagggtt gatcgataat caacggagtg attaattggg gctttcccgc ccttcctacg
      481 ctatgggtcg tgccgcaacc tccatgatgg ataacgccgt cgcagtgcgg aaatatcaaa
      541 ttatgcggaa ccggctgctt cattaagaat aaatgtttat ccgcttgtaa ggtgattcct
      601 gtctttgccc aaccggaacc gatgatgagc cgataatcat gtttcttgca aatatcgacc
      661 aaggctttgc tgaaacggtt accatccttg gaactacaac tcccgagggt aaaaaagata
      721 atagggcttt gagcgctgtc gacgaatgat atcatttcct cgtaagcctt ctcatcatat
      781 tgaaaagtgt cattgaagca atagcctccg atcgaccatt cgaacgtcca gtccggatct
      841 acgtttccta ggtgctggct gaaaagcaag taattatatg aacgctctcc cgcgtgatag
      901 ccaaaattgc ggatcggagc gagtccgtat ttagcccggt tcttattgat cgtgtctttg
      961 accatgaaat tggtcatccg gttcatcaac ttccatagga tagcgggagt gatgatcggg
     1021 ttgggtttgg gaaatggcaa tacggccggg ggaatcttct tacccggcaa gaacggggcg
     1081 taggcggtac gtatcaaggg tttcttgcaa tactcggcga tacttgcgac agcaaattcc
     1141 gagttggtcg atactaaaat atcatgctct tttagtaggg gaatcaattg atcgaactgt
     1201 ttatcgatca cgttccgcat ccatttaagg aatggccgga atttatgtga gttttgcgct
     1261 gcgctatcga tcatgccgcc gatatcgtca aactgttgca atacgtattt aaatccgtag
     1321 ggtttaacgg tctcctcgaa tatttgaggg agattgatgg tcacctcatg accgcgtctt
     1381 tccaattcgg ccgctatggc caaataagga aggacgtcgc cttgtgagcc tctggttact
     1441 aatagtattt tcatgctacg tttatttatg ggctatgagg gtcttgttta ccggatattc
     1501 agttgacgca aacgctcgat gtccagatgg tatttggctt ccatcgtttg tagtttctgc
     1561 tcattgatgg ctaagggatg attcaatcgt ttcgtttccc ggtatccttt atatacggag
     1621 cgaatcatct tacgtggatt gaaaatgacg gatgaggtga tccagcagcc gtgcgtacac
     1681 caacagttgg ctttataccc atgtccgata gcggctattt ccagtttcat cgcttcgcta
     1741 ttcatcactt tacttatatc gcaaccatac tcttttatat ttccgagcgg ttcccgtaac
     1801 tcgcaggcac gaaaacgtcc gtcgtagtcg attaccaagg tagtctctcc ggccgtacaa
     1861 tccatccccc aaggggtcgg gtgatctatg ttgctggcac gcacattata taaggtacgt
     1921 ataaggccga gatagaagaa gcgtgtgatc ggtctcctta agccggtggt atccgctacc
     1981 atccgatccg cataagctga atagataggg gatatgtcat cttgtatttt gcgtagcgtt
     2041 gactcggtta ggattttcac gccatcgtca cgggtcatgc ctctggcggc ctcaatcgta
     2101 tgtgtggagg tacggaaacg tccgtatacc caagtcatga agtcttctac ctggtctata
     2161 ttgtatttcg tgataacggt tgctatattt ttcaggacct tgccgtcgtc tccgaaattc
     2221 tcctgtatct tacgcagggt ttccagtgcc ttatagaagt ttccctgtac gcctctctgt
     2281 gtatcgtggg tcgtaccgaa accatccaag gaaaggctta cgttaatatt acaatccggg
     2341 cagttctggc ggaaccgttt tacccattcg acgatccggt ctggttttaa gccgttcgta
     2401 gggatgttca catctttgat atggttgttt ttgtagaata actccaatat ttccggtaga
     2461 tcctcacgca gggtaggctc acccccggat atccataatc ggttgaattg cccaacggtt
     2521 tctgatattt tcttgatttc atcgaaagtg aggtcgggtt gcttcttatc catttcttgg
     2581 gcatagaagc acatcgcgca tttggcgttg catcggcctg ttacgaaaag gaagatcgac
     2641 tcgagttttc tttccgtgct cattgccctg aaagaactgg tggttcgttt tttgtccatt
     2701 ttatttttgt tttaccattt gtcttatctg gcgcatgatt ttttccttgt gtttgatcaa
     2761 cacccggaga aaataacata agaagccaaa taaaatactt attagcatat actatatgat
     2821 ctttaaaggc aaagatcgac gataaaatga cgctaaacaa tctctatttg cagtattttg
     2881 tggtccatgt ttaaaaggta ggtctataaa caattaaagc ctgtctcacg acaagcccta
     2941 accaaacttt gttaacctta aatctaatac tattatgaaa aaaccacgat gcaaatatac
     3001 ggacttttca attcctgtca agatctgtag tgctaaatta tgtttttcaa catataacaa
     3061 aaataaaaag gcgcctttct tttagagaaa gacgcctttt ccatgatata ctaatcaaat
     3121 attagtcttg tagcttagcg caaatgaact cacggttcaa acgagcgatg ttactaacgg
     3181 agatgttctt cggacactcc atctcgcaag cgcgtgtgtt cgtacagtta ccgaagccaa
     3241 gttcatccat tttagcgacc attgctttcg cacggcgggc agcctctacc ttaccttgag
     3301 gtaataaagc caactggcta actttagcgg atacgaacaa catagctgaa ccgttcttac
     3361 aagcggcggc acaagcgcca caaccgatac aagcggcagc gtccatggct aagtctgcgt
     3421 ccttctttgg gataggtatc gcattagcgt cgggtacacc acctgtgttg acagatgtga
     3481 aaccacccgc ttggatgatt ttgtcgtaag cgtagcggtc taccatcaag tcgcggataa
     3541 cagggaaacc tgcggaacgc cacggttcga tcgtgatcgt ctctccatcg tggaaacgac
     3601 gcatatataa ctggcaagtc gtagctccag ttgccggtcc gtgcgggtgt ccgtttacat
     3661 acaatgaaca catgccacag ataccctcgc ggcagtcgtg atcgaatacg atcggttcct
     3721 taccctcgtt gaccaactgc tcgttcaaga tatccaacat ttccaagaaa gagacactct
     3781 gattgatctt ctcaattttg tatgtctcga actgtccttt ctccttcgga cctctctgac
     3841 gccaaacctt aagtgttaca cttatatctt tatccatgat tctaattttt tctgagattg
     3901 atgattatta cttcttgtag ttacgtgttt gaggaacaac gaactcatag ttcaaatcct
     3961 ctttcaacat gacaggatct ttgtcctcgc cttggtactc ccagcaagat acgtacatga
     4021 acttatcgtc atgacgcaag gcctcacctt cttctgtctg gtgctccgta cggaagtgac
     4081 caccacaaga ctcagcgcgg tccaaagcat cgtgtgccat caatgtaccg atctcgataa
     4141 agtcggctac acgtaatgct ttctctaact cggtattcaa gttgtctgcg ttgcctggga
     4201 tgaatacgtt gctccagaac tctttcttca agtctttcag catctggata gcttcttgca
     4261 aaccttttgc gtcgcgtgcc ataccgatat gttcccacat gatatgacct agtttgcggt
     4321 ggatagtgtc tacggtttct ttacccttga cgttcatcaa tttttggata cgatccttga
     4381 tggccttttc tgcctcgacg aactccggca gatccgtgct gaagcgagga acttggattt
     4441 ggtcggacaa atagttctgg atcgtgtatg gtaatacgaa ataaccatcg gccaatccct
     4501 gcatcaaagc ggaagcacct aaacggttcg ctccgtgatc ggagaagttt gcctcaccga
     4561 tagcgaacag acccggaatg gaggtcatca actcatagtc aacccacaat ccacccattg
     4621 agtagtgcaa tgccgggtag atcatcatcg gagtctcgta tggattatcg ttcgtgatct
     4681 cttcgtacat atcgaacaag ttaccgtatt tctgcttaac gacctcttta cccaagcgat
     4741 tgatcgcgtc ggagaaatcc aagaatacgg ccaagcccgt gctgttcacg ccgaaacctg
     4801 cgtcgcaacg ctctttagcg gcacgagaag ccacgtcgcg aggaaccaag tttccgaatg
     4861 ccggataacg acgctccaaa taataatcac ggtctgcctc gggaatatct ttacctttct
     4921 tcgttccggc ctgtagagct ttagcgtctt ccagtttctt cggaacccag atacggccgt
     4981 cgttacgcaa ggattcggac atcaaagtca atttagattg gaagtctcct ttcaccggta
     5041 cgcaagtcgg gtggatctga accatacaag gattagcgaa gtaagcgcct ttcttgtagc
     5101 attgccatgc ggcggaaccg ttagatgcca tagcgttggt tgacaagaag aacgtattaa
     5161 cgtaaccacc cgtagctaca actacagcgt gagcggcgta acgctcgatc ttacctgtaa
     5221 tcaagttgcg ggcgatgata ccacgagcac gaccgtctac cttaactaca tccaacatct
     5281 catgacgagt gtacatctta accttaccca aaccgatctg acggctcaac gctgaataag
     5341 cgcctaacaa aagctgctga cccgtctggc cacgggcgta gaacgtacgt gatacctgag
     5401 cgccaccgaa tgaacggtta tccaacaaac caccatattc gcgagcgaaa ggaacgcctt
     5461 gagccacgca ctggtcgatg attgagttag aaacctcagc caaacgataa acgttagcct
     5521 cacgagcacg gtagtcacca cctttgatcg tatcgtagaa caaacggtaa acagagtcac
     5581 catcattctg gtagttctta gcggcgttga taccaccttg agcggcgata gagtgcgcac
     5641 ggcggggaga atcttggata cagaagttca atacgttgaa tcccatctct gccaaagatg
     5701 cggcagcgga agctccggcc aaacctgtac cgactacgat aacatccaaa cgacgcttgt
     5761 tagcggggtt caccaatttc tggtgatttt tataattagt ccacttctca gccaacgggc
     5821 cttgaggtat tttagaattt atttcagaca taatgattta atttcaaaag ttcttaatta
     5881 taaaacctgt agcttgcaat taagcaccta ctccgtttag gaagaagatg atagtaatga
     5941 tcgcgaaaag tccgcaaata accgtagcta cgatcttaga gatacattcc caacggttca
     6001 tccagatcgt attattccaa ccaattgttt ggatagcgct ccagaacccg tgagtcaagt
     6061 ggaaccacaa agccacgtac cagatcaaat aaagaacagt gatcacggca ttaccttgga
     6121 agtaatagtt gataaaagcg gctccgtctt gtggagatac catagctgac cccaatgcaa
     6181 cttcgtgatg accgatcaat tcggcgaaca tcatcttata ccagaactgg ctgaagtgca
     6241 acagcatgaa caggataacg atcaaaccca aaacgaacat gttctgagat gcccattcca
     6301 cgcctttcgg acgagcgttg atagcgtaac ggtcgttacc acgtgcctta cggttttgca
     6361 aggtaagaat gatagcgtac acgaagtgga tcacaacgcc tgcggccaat acgagagtag
     6421 ctgccacagc gtaccaatta gagcccaaca gcgaacaaac catgttataa gcctctccgg
     6481 agaaaacggc cgtcacgttc atcgacaggt ggaacaataa gaacagaaca agaaagaggc
     6541 ctgatatact cattatcagc ttcttcccga tagaagaatt aagtaaccac ataagataat
     6601 aatttaagtt atttaattgt atttagaaat ttctacttaa actatgtaat tatcacgcaa
     6661 aggtatgcta aatccatata ttgcgcaaac gattaaagaa atatttctgc attaatggga
     6721 gaggtcaggg catgtgtccc gacacatgga ataatgcgga aggaaaaggc tttccttatg
     6781 aataatttat atacatttgc ctatatgcgt aaggatttga atgggccacg gcatttttcc
     6841 atagggatca agtttacgat cttattattt acgatcgtga tcttggttct tgtgcttttt
     6901 tcatatagga gtgacaagca tggcaacctg ttctggcagg tagagaaatt gattccgcat
     6961 catccggaca gtgctttggt gttattagag aaagtgaggg atatcaatgg attatcgctt
     7021 cgagagaaag cccgttattg tctgttatgg accgaatcac gggatgaggc gggattgagg
     7081 catacatcgg attccataat ctctatcgct acggattatt ataggacgac acgaggctgt
     7141 tactggccac ccaaagcttg gttttaccgg gggaaggtct atgaggatat ggatcaaccg
     7201 tccctagctt tggaatgcta tttacgtgcg ttggaatatg agggagggaa ttgggattac
     7261 gaattttggg gacggttata taaccagata gggaggctgt acgccgagca ggaattatat
     7321 ggcaaggcta tgtctttttt gagaaaagcg agtgcccaat atcagctctt gaatgatacg
     7381 gccggacaag gccggatact ggaggaagtc aagaaatacg aggcgttacg ggattctatc
     7441 ggatcgctgt cagcgagaga atcgatttat cagatcactt cccggtatga tgtaaggccg
     7501 gttcgtgagg acttatatag gaaagaattg atgctatcgc aaaggggaca ggagcgttat
     7561 ctgtacgcat ttattatcgg cataatccta tttatttgct tcctccttta tcggcgatgg
     7621 agaaatacgc aggaaaacgc tcttcgaagg gaagaagcct tgcgacgctc gattgctagc
     7681 cagcaacaac gtatgcgaga agaaaaagaa gggaatgaac ggcaaatcgc ccttttggaa
     7741 aagagaatta cgaaaataaa ggaagaaaag gatcaagagt tgatgttggt ttccttacaa
     7801 ttggaaaaac aacggctgga gatttgtaac gagtcgattc ataataagga gagtaagcat
     7861 ttattatctg tcgcgatctt gcggaaatcg gaggtctatg agaagtttca cgatcgggat
     7921 gccggcaaga ttatctctga ggattgggag cttttggagg ttttgttgaa taaggcttat
     7981 gatgacttta ccttacggct gaaaaaacta tatcctgcta tttccgatac ggagttgaag
     8041 gtctgtatgc ttacgaagat cggcgttccc gccaaccaga tcacacgggt attgaaatat
     8101 aatagttcgg tacttcgtcc tcgtctattc cggaagattt ttaagaaaga aggttctacg
     8161 gagacatttg tggagtttat ctcaagtttt tgattattat gtatttatag ctgttttggc
     8221 aggtttgttc tcatttttgt tctcatttat catgtgattt gtgagatatg cgggatattt
     8281 ttggaggcaa aaaagcatgg ttatgaaaag tgtaaagtta gcctctatct tgttttattt
     8341 aaatagtgtt tttgtcgttt cttgtttcgc gtcatgcggt tcttcgccaa cggaagcgtc
     8401 ctctctttta accgcagata taagaggggg gatggataaa ccggggctat tgggattagg
     8461 cgatgagatc aagggggtta cttttgtccc tttagaggtg accacggatg atgcctcgtt
     8521 gatagacgga gtttatgatt atgccgtgac agatcgatat atctatgtgc ttcccgtaaa
     8581 agagccccgt atcgtcctgt tcgatcggca agggcgtttt atccggacgt tggtaaaaga
     8641 agggcagggg ccgggtgaat ttagaggtat tctgccatgt atccaagtgg acgaacgtaa
     8701 tgatcgcctt tttttattta gtaataatcg agtttgggaa tatacgttgg aaggtgaatt
     8761 tatcggacaa tccacccatg agtattcggt aatctatatg cgtcatatcg gaaaggatcg
     8821 tttcgccgcc atatcattcc cttttcagcc tttcaacgga ggaggattcg gattaggcct
     8881 attttcgagg aaaggggata cgatagcgat caagaatgat ttttattcct ttttattacc
     8941 ccatgagaag agcgggttca cgacaagtat cgcccccgct tattctgatg cgcaaaactc
     9001 tgtgttgttt aagaccggta gtaatgatac ggtcttctgt atctcggcgg atcgaataag
     9061 tgcggcttgt gtccttgatc tgaaaaactc ggatgcggaa gtgattcgtt cgttggatgt
     9121 tacggacatg agtaatttgc gaattgaaaa aaaggacccc aaggatatct ttgtgcaaga
     9181 tatgattgag tttccgggac attattattt ccgtttattg tataaccaag gctattatat
     9241 agcctctgta gataaaaaga cgggaaagac acttgtggaa aaatgtgtga tgccgggttc
     9301 tatctatgaa ctggcggatg cgaaccttca acatggcatg cagggtacga gaagttatcg
     9361 gaatttcccg gtctggggga gggtcataaa agatgagctg gtacaagtag tgaccccgta
     9421 tgagctaaac ttatataaat cgcttcgctc gatcacgatt ccgcaggagt tggacttaaa
     9481 aggagaggag ggcaatccgg tttttgtgtt ttattcgctt atctgacttc gatatgtatc
     9541 gctcggttgt acttcttgta ataatctagc gatagaagct atagtattca tggttactat
     9601 ctatagaaaa tctgatttac tattgatagt aatctgattt attatagata gtaattggat
     9661 cggtaatagg cgtgtatgta taactgctta gatatcagcc atatactaat atttacgtgc
     9721 aaagtgggca tattgtgtat tttaactgtt cggtaaataa tcgtgttctt ttatcttttc
     9781 tatgcctttg atggctatta gtgttaatta atgtattgtt tatatttata ttacgagcat
     9841 ttcgtatatt tgcgaaacca acgtaatatc cggatatgct tagaggttgg taagtatgtg
     9901 taataacggt ataaataaca ttaaaacgga ttgaaaatga aaaaggcgat tatgaacaca
     9961 atgatcatcc tgttcgcttt ggcgatgtgc gtaggatgcg gacagtcttc ggaacaaaaa
    10021 gaagaaagtg ttccgacaga tgtaacaaag gcagaaaaac aagagcaagt acaggtggaa
    10081 gcggaggacg aagatacgct ggaaaatgga gagcaggtat ttagggtagt agaggtgatg
    10141 ccgaagtttc ccggcggtga tgcggagctt ttgaaattta tagccaagaa tgtaaagtat
    10201 ccacaagaga gccaagacaa aggagagcaa gggcgtgtga tttgttcgtt tgtggtaacg
    10261 aaggatggaa cgcttacgaa ttacaaggtc cttagaggaa tctccccggc attagaccaa
    10321 gaggcggttc gagttttgca aatgatgcct cgttggacac cgggcacgca aagaggcgag
    10381 ccggtagccg tgaaatatac ggtgccgatc acgtttaagt tgcaataatt cacgattgca
    10441 ggtcttgtga ttcttattta atgttaatta acgtgccttc cgcatgccgt ttacgactat
    10501 ttcgtagctt tgtggatata cattaaataa aaggataaga tttatggaga agctaacgat
    10561 gcaggaagaa gaggcgatgc gctggatttg gcggatcggt ccttgttttg tgaaagatgt
    10621 gctggccaaa tacgaggacc cgaaacctcc ttatacgacg ctcgcttccg tgatcaagaa
    10681 tctggagcga aagaagtacg tgaaggcgaa acgttatgga aatacgtatg aataccgtcc
    10741 tttgatagag gaaacggaat ataaacgtac gttccttggg ggcgtggtaa cgaattattt
    10801 cgctaactcg tataaagaaa tggtttcttt ctttgcgaaa gatcagaaaa tctctacgga
    10861 tgatttaaag gatatcatcg atttgattga gaaaggaaaa gaataaccta aatcccacat
    10921 accatgacac cggaatttgc ctacttattg aaggtaaatg tagcctttgt actcttttac
    10981 gccttctacc ggttgttctt ctataaggac acgttcttca agctacgtcg tgcgatcttg
    11041 ctggcgttct ttggcttggc tctgttttat cctttgctga acatccaaga ttgggtaagg
    11101 caacaagagc ctatagcgga cgtgatttat atgtattccg ctatgttgcc tgaggcgacg
    11161 gcgaaagcgg atgccgcggc gtccgtggat tggtatggat ggttgttggg atctttgggg
    11221 tttatttatt gggggatcgt agcgttctta tgcggacgtt ttctcgtgca attaagcagt
    11281 atcttatggt tggttcatac cagtgagcgt gttgttattc atgaaactcc ggtttatgcg
    11341 ttgcggaagg ccgccgggcc attctccttt ttccgtatgg tcttcttgca tccggagagt
    11401 cattcggata aggaaacgga tgagatattg acacatgaat gtacgcacgt atcccaatgg
    11461 cactcgattg acgtgatctt gagcgagatg atgtgtatgg cttgctggtt taatcctttt
    11521 gtatggttat tgaagcgtga ggttaggcat aatctggagt atctggcgga taacacggtg
    11581 atccagtctg gttacgatag taagagctat caataccatt tattgggatt ggctcatcat
    11641 cagtccgtta ctactttgta taatagtttc aatgtgctgc atctgaagaa ccggattatg
    11701 atgatgaaca agaagcggag cccgggtatc gtacgtacga aatatctgat atttattcca
    11761 ttggtaggga tcttgatgct gttaagtaat atcgaggcgg tagcccgttt gactgtccgt
    11821 ctggcgaatg aggctacggt ctcgaacgct gtggtgacgg ctacgggcat tctggttgat
    11881 gagactgggc agcctttgat cggggcatca gttgtggtga agggcggtaa agaggggact
    11941 atcacggata ggaaaggggc tttctctttg gaggtccctg cgaatgcgat tttgcgatgc
    12001 agctatcaag gaagggagtc ccaagaggtc ttggctgctg atatgacaaa taatacccat
    12061 ttgtccttat cttccaaatc ccgtgagatg aacgagcaag tatttaccgt ggtagagaag
    12121 atgcctagtt ttccgggtgg ggatgcggag ttgttgaaat acatagccac gaatataaag
    12181 tatccgaaag agagccagga taacggggag caagggcgtg taatctgctc gtttatcgtc
    12241 gggcgtgatg gttctgtcaa taatccggag gtgcttcggg gagtgactcc tttattgaat
    12301 gaggaggccg taagggtaat aaacactatg cctcgctgga atccgggaat gcaacgtgga
    12361 aaggcggtcg ccgtgaaata tacggtcccg attacgttcc gtttgaaaag tccggtagaa
    12421 gaaatgaagg aagagacttt gacggtagtg gacgtgatgc cgcaatatcc cggaggggat
    12481 cgtgaattat taaagtttat cgctcaaagc ataaagtatc cgacggatgc gcaggaagcg
    12541 ggagtgcaag gtcgtgtgat ctgttcgttt gtggtagata agaaaggaaa tatcgtggaa
    12601 cctaaaatca tacggggaat agatccctcc ttggatgcgg aagctttgcg agtcatcgga
    12661 atgatgcccc ggtggactcc cggtcgtcag gacggaaagg cggtccgcgt cttatatacg
    12721 gtgcctatta ctttccggtt acagtgaaat aagaatagag gctatgttgg tcgcttaatc
    12781 agtaatctta aaaatataca gatatgaatg cgaaatgtaa tttagttaca gttctgttac
    12841 tttgttgcct tatttttccc ggaaatgctc aagagtttaa ttggcaagac ttggtgaacc
    12901 gtaagcaata tgcggctgtg atcgctcatg ctgatagcct tacactagct gattcttcga
    12961 attatgagat tatgaacgct atcgggcagg cttatgaggg tatgcttcgg tatcagaagg
    13021 cttatgacta ttaccgtctt tgcttttcta tggatacgac gaacttggat atcttaaaca
    13081 tcttggctcg gacggcgacg aacttaggcc gtgcggagga tgccgagcga tattttcatc
    13141 aggtattatc cgccgatagc tcgaacttct acgctaatta tcagttggca cgtctgtatt
    13201 tccaattggg ggagtatgag aaagcagttg atgcctatga gaaattgcaa gctcagaatg
    13261 aggataatac tgtcttatac cgtgcgattg gcgattgcta tactcgaatg gaacaatatc
    13321 cttctgctac gaccgcttat tttcaggcgt ataacttgaa tcgtgagaat gcggggttgg
    13381 cggttgcgtt agtgaattca ttgtatcgga tgggggctag tagcccggat tatatatcgg
    13441 aaggaatagc gatttgcgat accgccttgt tttataatcc cgggaatcgt caattattgc
    13501 gtagtaaagg attggggcta tatatcgtga aacaatttgt tcaggcggat tctgtctatt
    13561 ccagtttgtt ggctgatggt gattccacct accttacctt gaaatatggg ggagcctcga
    13621 agtattatgc cggtctgtat atgccctcgg tagatatctt ggatatggca tatgagcagg
    13681 atacgacctc tgtcgaggta tgcctcttat tgggttccgc cttgggtaag acgtatgacc
    13741 ggaagcgggc ttacgactta tttgaccggg cggaaaaggg attggaaccc aatcgtttct
    13801 tggtaaatca attattggcc ttccgtgcgg agacttacca aaaagacggg agatacaagg
    13861 aagcgtcccg tctctactat gaggcatgga agaagaatcc ggaacgactg gatttcctag
    13921 cggcgatctc gcatatgtat agtgagattg acgtgtctaa attccagagt gaagaggatc
    13981 gtcagcgagg tctttttatc ttggtacttt atatgaatga gagcttaaag aaaaaagcgg
    14041 acgagaggac gatggtgttt agccgggcgc ttctgcaatc cttctatgag gatatgtttt
    14101 tccgtaatgt ggcggaggag actatgatag acccggatgg gaaaaagagc aagatatcta
    14161 tcgtggattt gcgtaacctg atcaatcaat tgccggagga atcggagatg gtcatggaga
    14221 ttcgtgccat gagcgccaga agctcgggta agatagagga ggcggctcgt ctgctttatc
    14281 gggcgtggga ggtgaagggt actcgtgtag aattgcttcg tgagattgcg aacctatata
    14341 gccatccgga tatctccgga ttcaagaatg cggaggagct acagagaggt gtattcgctc
    14401 aagtgactta cgcgaaggaa ctgttgaaaa acgagtcgga tctgagtaac ttgactttta
    14461 cccggccttt cttggagtca ttaaattcgg atatgtccaa acggggtatc acggagcaaa
    14521 ccatgctggc tccagataac cggaaaagcc agctttctat aaatgaactc caatctctga
    14581 tccaacaact gccggagaca tccgatgagg taaaagagat gatacggatg atgaacaaag
    14641 agaaagcgct aaagagcaag aaatgacatc gaacgaaaga ctttaaacat cataaaaaat
    14701 gagaaaatta actacgaacg cagtggctat gctactcgct ttagtcggat gtatgggatg
    14761 tggcaatcgg tccgcttcct ctgtcgataa ccttataagg gttgatgtca tggccgatta
    14821 tccggaaaag gaactgatac ttcaagacct catggacgtg gaatacatcg cgttggaaac
    14881 cacggatgat tttataacta aaggtgccgt gaaagcgatc ggaaaggata tcatgctggt
    14941 gacgaatcgg ggcagtgatg gggatattct tgttttcgat agaaacggaa agggactaag
    15001 gaagataaac cgtttagggc aaagcggtga ggaatacacg cagcttacag ggcttgtctt
    15061 ggatgagggt aacgatgaga tattcgtcaa ggataatcca gcgagaaaaa taggtgtcta
    15121 tgacttatta ggaaactata aaaggagttt taagttcacg gataccagtt attataatta
    15181 tatatttaat tatgatcgtg atcatttgat ttgctataag agttatccat cggaaaaagg
    15241 caagcgggag tgtcatttga ttatttccaa acaagatggc cgtatcattc atgagatcca
    15301 aattccctct aaggggactg agactccggt tgtaacagaa ggggagttta tcattacgcc
    15361 ggaattttat cttacgtttc cggatcggga taaatggata cttgtcaata catcgtctga
    15421 taccatattc cattacttgc cggatggtaa tctgagtcct tttatcgtaa gaagcccttc
    15481 catatcctcc atggatacta aagtatttct ttttccaacc gtcatcaccg atcgctactg
    15541 tttcatgaga accatgagaa aagaggttga ctttacgacg tttaaaggtt tccttggtga
    15601 atatctggtg tatgataaac aagaaaatgc cttattcagc tatattctat acaatgatga
    15661 tttcatcaat aaggaagaag tctctctaac atcagagcca agaaaccccg aaatagctat
    15721 ctgccaaact ctagatgccc cggacttagt tgaggcttac gagaaaggcc agctaaaagg
    15781 aaagttgaag gagatcgccg caaacttgga tgaagagtcg aatcctgtgg tcatgctgct
    15841 gaaaaagaaa aagtaatata ttgctccggc tgctaccttg ctggaaaaaa gtaagttgat
    15901 ggctatatta ttttttgata aacacgtaca tacctgattc ataatacgta aatcgatttt
    15961 agagagaaat gcctattaat tctagggaga ctgtatcaaa tactatctat tgcccactta
    16021 tgttccggaa ataaaatgtt cctctcctgt tgaaatagtt ctccgataac ctatacattc
    16081 catagcgaat aagtatttat tcttaaatca gcgccgtgaa ctgtataaac cacgccgtgg
    16141 aatgtgcaga ccacgccttg gtttatacag ttcacggcat ggtttataga atagatgaga
    16201 tagcgataaa ctttatatat aggtaaacat acgttttatt ctagatgaat ccgtttgcgt
    16261 tttcgagtaa accagctaca tttgccggaa agaatatcta gatgaggaag ttccttttat
    16321 tgtggttggt tgggttgatg ttggtgcctt ctgtgatggc tgagcggaaa aaggttggct
    16381 tggtgctggg aggcggtggg gcgaaaggtg tcgctcatat cggggtgttg aaggtattgg
    16441 aggaggccgg tatcccgatt gattatattg ccggaaccag tatgggagct atcgttggtg
    16501 gcttgtattc cgttggctat actgccgctg agatcgatag catggtacgt tggcaggatt
    16561 ggagcatgtt gctaagtgac cgtgtgaaac gt
//
