LOCUS       c00026_gnlPro..        14089 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ILNKOMKB_26.
ACCESSION   c00026_gnlPro..
VERSION     c00026_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 20:53:41
            Original ID  :: gnl|Prokka|ILNKOMKB_26
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14089
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..303
                     /locus_tag="ctg26_1"
                     /transl_table=11
                     /translation="EKNRKALLDKYKTFEKFNEKFEIDDQLLNYLREAADKEKIEFNEE
                     QYNKALPLIKAQLKALIARDLWDMNEYFQVMNATNKSVERALEILNDKEYEKILK"
     protocluster    1..14089
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2683:6144]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2684..6144
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14089
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14089
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(387..1010)
                     /locus_tag="ctg26_2"
                     /transl_table=11
                     /translation="MKKFVLICFCVLSSVGGYAQNWDINTLHKINSLDSKFARNYSKAF
                     SKSAPYIAVGVPVAMAVYAGIDKDKELLKDAIYIGTSVAEAVVITYGMKYAFDRERPYD
                     RYPDRVDARSHESSPSFPSGHTAAAFSLATSLSIRYPKWYVIAPSAFWACSVGFSRMNE
                     GVHYPSDVAAGAVIGAGCAVANIYVNRWLNKWLFGEKKKVTISY"
     CDS             1126..2001
                     /locus_tag="ctg26_3"
                     /transl_table=11
                     /translation="MARETQCNRQTDCAQCPKATEGILVHRKFPKGQHFPPDKCTQNCI
                     LFILQGELLVNSEEYPGTTLREGQFILQSIGSKLELLALTDVNYVVYWFNEPPLICEQR
                     YHEILQQSEAPLTYTPLVMTQRITNFMKDICDYLDEQMPCGAFIDLKCQELIYLIICYY
                     PIPQLSKFFYPISSYTESFQYFVMQNYEKVKNVEEFAHLGGYTTTTFRRLFKNMYGVPV
                     YEWILSKKREGILEDLQHTKQRITEISNRYGFDSLSHFAHFCKASFGDSPRALRTRAAR
                     GEKITALKTE"
     CDS             2684..3376
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_4"
                     /sec_met_domain="SucD_FumR (E-value: 2.4e-121, bitscore:
                     392.4, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVAIISAEGYNLV
                     CEFLGANWYALVATLGLAALFVIHIIYAFWLTIQNRAARGSERYAVVDKPKTVEWASQN
                     MLVLGIIVILGLGLHLFNFWAKMQLPELVHNMGGVADTTYAADGVYHIMNTFSNPVYVV
                     LYLVWLGALWFHLTHGFWSSMQSLGWNNKIWINRWKCISNIYSTIVVVCFALVVVVFFV
                     KSLACGAC"
     CDS             3414..4481
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 127.5; E-value:
                     2.4e-39)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_5"
                     /sec_met_domain="FAD_binding_2 (E-value: 5e-40, bitscore:
                     127.5, seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKIDSKIPEGQLAEKWSNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFARDYGGTLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQVQKGTVKLYTRYEMLDLVVIEGRARGIIARNLVTGEIERFAAHA
                     VVIGTGGYGNAFFLSTNAMGSNGSVAIQCYKKGAYFANPCFAQIHPTCIPVHGDXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXALKSRPKFLMKTVTSIWNAVTRHSVTLFRVT
                     LLHVQPKNVVMPVSV"
     CDS             4478..5359
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_6"
                     /sec_met_domain="FAD_binding_2 (E-value: 4.9e-15, bitscore:
                     45.2, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 4.1e-39,
                     bitscore: 123.3, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VNNTGLAVFLDFKYAIDRLGEDVVRARYGNLFDMYEEITDENPYK
                     TPMMIFPAIHYTMGGIWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLADQIQVPRFSTDLPEFAAAEKEVKDKIQKIKAVNGKHSVDSIHKKLGHI
                     MWDFVGMARTKESLQKALTGIEEVKKDFWTNVRIPGDVNELNVELEKALRLIDFIEVGM
                     LMARDGLNREESCGGHFRTEYQTPEGEALRDDKNFSYVACWKYTGENSEPELIKEDLNY
                     QFVKVQTRNYKS"
     CDS             5389..6144
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_7"
                     /sec_met_domain="Fer4_7 (E-value: 1.2e-12, bitscore: 38.1,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 1.6e-26, bitscore: 82.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.7e-07, bitscore: 20.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQKGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQIINDGGEPIVFDHDCREGICGMCSLYINGHPHGPATGATTCQMYMRRFKDGDTITVE
                     PWRSAGFPVIRDLMVDRSAYDKIMQAGGYVSVNTGAPQDANAILISKDIADEAMDAAAC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKVEAARRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNISISNIARLNRDFIIAKLKD"
     CDS             complement(6225..7355)
                     /locus_tag="ctg26_8"
                     /transl_table=11
                     /translation="MNKTFRKACAKLHLWLGLLSGIVVFIVCITGCMYAFKDEITDATQ
                     PWRFVAPLEKEFLPPSRLLAIADSVMGGASATAITYGERSDAAWVDYYQPEAGMSTVFI
                     NPYSGQVLKSVVNHNGDFDFFRLVLSGHRTLWLPREIGSPIVGYSVLIFLITLITGVIL
                     WWPRSWTRKALVQRLTLKRPFTFSRLNFDLHNVAGFYAALVLAVLCFTGLIFSLNWFSR
                     GVYSITSGGEELKPYVLPVSDTLQVVNRVTNPLDRLYTQLRLEEPAAKTFYFALPGQAD
                     GVYRVSVVHKRGSYYRTDNLFFDRYTLVSLKGAGPYAGKYTEASPADKFRRMNLEIHDG
                     RIWGLPGKIIMFLASLTGASLPVTGFIIWYRKRCKR"
     CDS             complement(7362..8582)
                     /locus_tag="ctg26_9"
                     /transl_table=11
                     /translation="MITMYRIYMYLLAACLLLGVTACEEEGLGNEETPFAPYVLSLGIN
                     SNGTTTYYVVTAPELMSGTINAVAKGIEQNGYRDYEQAGQTVFSIGGLGLTSATGIVRD
                     ANGYLTERGDFVFNSSLNAFTQMDGQNMIGLELPANKESGDQMTLYTVNISDVSITSQV
                     KAPVFPLNQLEWPSITGMCYSEGNVYVTYFPMNPSTFETLYTDTTFVAVYSYPDMQFKT
                     LMKDTRTGPAGSWNAFNGIFKVESGDMYIMSNSAIANGFSQSTKNAAFLRIPKGETHFD
                     DYYFDFETVSGGLKPAHIKYIGNGLVFAEVSTISPQTSADRWGDKSLKCCIIDLNNKTV
                     RDIKEIPVHNGDGGRRFAALVDGGYVYRPVTTSEGTYIYQVDPQAATAVRGAKVSTTFV
                     GGFFRLD"
     CDS             complement(8592..11009)
                     /locus_tag="ctg26_10"
                     /transl_table=11
                     /translation="MNHKVLYRVALFCLFSMLSAVLMHAGEQQQQSKGIVTGRIVDQQK
                     QPYYPVAVAIEGVYIGGYTNENGVYHINDVPAGSQTIVVSGIGVKTKKVPIHVTAGKVN
                     RIPDIEIDTQAEELEEVQVIGKSEARRQQEQAYAISVLDIKKAYNSAAPLNKLLNNVSS
                     VRIREEGGMGSNYNFSLNGFSGNQVKFFLDGIPMDNFGSSFNLANISANMAERVEVYKG
                     VLPVNLGADALGGAVNIVSRRDANYLDATYSFGSFNTHKVSVNGAYTHLKTGFTVRANA
                     FYNYSDNDYKVFVPIIDLATNKKIDERWVKRFNDAYRSGGIRLETGITNKPYADYLLAG
                     IILSKNDKDVQTGATMDAVYGGVKMKSESVIPSIRYKKDDLFLDGLSLSLYGTYNSVNT
                     FNVDTIARRYNWLGESVPSTSAGEGYYTDSKIKNREWLGNGNISYVIDGHQSLILNHVV
                     SAMRRTMNDKVRPDDENNNVPQQLTKNITGLGWQIRYDRWNANVFGKMYKLYSSTYKRL
                     DEYTENARWEKVRDHKTNFGYGAAATYYILPSLQAKFSYEHAYRLPESIEMFGDGLIQQ
                     RNPDLKPESSRNLNLGLSFIQTFGAHQLSADGNFIYRYTTDFILKGVSLTSNPTTGYEN
                     LGKVLTKGVEAAVRYNYKDLFHTGAGFTYQDITDRQRYEKTKDSFVGEGITENITYKER
                     LPNIPYLFANADAGVRFHDLIWRNSVLTFDYNLNYIHSYYLSFPGLGAKSSKKVIPEQF
                     SHDLALGYSMDNGKYSVVVECTNLTNQKLYDNYRLQKPGRAFNVKLRYFFSK"
     CDS             complement(11142..11987)
                     /locus_tag="ctg26_11"
                     /transl_table=11
                     /translation="MPSSVCGDPMMCQNCKKSVPNAIFHVYHRRGFHYPAQKCEENFIL
                     FLIKGEMLVNSREYAGTMLKAGEFMLQPISSKIEMLAMTDVECIYYQFNQPELFCDIRY
                     NRIMKETDPPLIPSPLPIIPELQHFLESARTYLSEKKICRDLLSLKRKELAFILGYFYS
                     DYDLASLVHPLSKYASSFECFVYQNYKKVKTVEEFAKLGGYSQTTFRRIFDNVFHEPVY
                     EWMLSRRKEEIIYELQNTEATISEICYKFGFESLPHFSNFCKKSFGTSPRSIRLKRSSE
                     "
     CDS             complement(12210..13223)
                     /locus_tag="ctg26_12"
                     /transl_table=11
                     /translation="MKKILFAAVAAMAITGCSQNEEIEKAVQPVEISFNTAVSKTTRAT
                     TLVNSAFTKFTAYAYSTTGAFADATEVNALISGTEFELKESTWGSGSSVFYWPATDQVS
                     FFAFSPNTTEQFSWGAAAAKTAPTLTYTVKDAVXXXXXXXXXXXXXXXXXXXXXXXXAV
                     ALNFKHALTKVGFKIKGEGSGVTYTLNKIVINAKKKGVYTYGATSTTSETTLGTWTIPS
                     DVTANTAYTVEPTKALSITGADNGGTANETLVGADYTAMLIPQDLTGVTFEIYYKAEAG
                     GAILCDKTTTPEEITFADGTWTAGQSVAYVLTLKGVEKMSITGSVADSWDFTDTPK"
     CDS             complement(13279..14088)
                     /locus_tag="ctg26_13"
                     /transl_table=11
                     /translation="RIIFYPKDEKGRKIDTYLSVTGGEVKVPSGHYAVVIYNYDTETVL
                     IRGEESYETIQAYTNFCKLGIAGTEKMVWGPDPLYVVNIDDLDIQNSEETLILKLKPKL
                     VIRTYSFSIKVQGLSNVSNVIGSIGGMADHYFLGKAYAMCDDYPINIDLNVKAGKIEGV
                     FTTFGLPEAIITRLEIKLPVMMNLMIIKVDNSVQEVKINITEAVQEPTGGGEGGEGEET
                     KPPALVEVEIEDEIKVDDVETPPSGGGGIGGDVGDWDDETNVELPVG"
ORIGIN
        1 gaaaagaacc gaaaggcttt attggataaa tataagacat tcgagaaatt caatgaaaag
       61 tttgaaatcg acgaccagct attgaactac ctgagagaag ctgccgataa agaaaagatt
      121 gaattcaacg aagagcagta caacaaagcc ctgccactga ttaaagctca gctgaaagct
      181 ttgatagccc gtgacttatg ggatatgaat gaatatttcc aagtaatgaa tgccaccaat
      241 aagagtgtgg agcgggcact ggaaatctta aatgacaaag agtacgaaaa gatattgaaa
      301 taacgtttct ataacggaaa acgatatacg gtgaatgacg aacagaccat gcttcctgca
      361 gcctgttcgt cattcaccgt atgtcgtcaa taacttattg taaccttctt cttctcaccg
      421 aacaaccact tgttaagcca gcgattcaca taaatattgg ctaccgcaca accagctcct
      481 atcacagctc ctgctgctac atccgacggg taatgtaccc cttcattcat tcttgagaat
      541 cccacagaac atgcccagaa agcagatgga gctatcacat accatttagg ataacggata
      601 ctcaaagaag tagccagtga aaaggctgct gccgtatgac cggaaggaaa cgaaggactc
      661 gattcatgac tacgtgcatc tacccgatcc ggataacggt cgtagggacg ctcacggtca
      721 aaagcatatt tcataccata cgtaatcacg actgcctcgg ccacactcgt accgatgtaa
      781 atggcatctt tcagcagctc tttatcttta tcgatacctg catatacagc catcgccacc
      841 ggtacaccta ccgcaatata aggtgccgat ttagaaaagg ctttgctata attcctcgca
      901 aacttactat caagactgtt tattttatgt aacgtattga tatcccagtt ctgagcatat
      961 ccccctaccg aagaaagcac acaaaaacaa ataagcacaa atttcttcat ttttctacta
     1021 atttactatt ttgcagcaaa gatagattaa aaagacagag ttttcgcaaa aaaaacctat
     1081 ctttgttccc taagtattat ttaccctgac acctaacttt aattcatggc cagagaaact
     1141 caatgtaata gacagacaga ttgtgcgcaa tgtcccaaag ctacagaagg catacttgtt
     1201 caccggaagt ttcccaaagg acaacatttt ccgcccgaca aatgcacaca aaattgtatc
     1261 ctgtttatac tacaaggaga attactggtc aacagtgaag agtatcccgg caccacatta
     1321 cgtgaaggac aatttattct ccagtcgatc ggctccaaat tagaattact ggcactgaca
     1381 gacgtaaatt atgtagtgta ctggttcaac gaaccacccc tgatctgtga acagcgctat
     1441 catgagatcc tgcaacaatc agaagctccg ctaacttata caccattggt tatgacacaa
     1501 cgcataacca acttcatgaa agatatttgt gattacctcg atgaacagat gccttgcggc
     1561 gcattcatcg atctgaaatg tcaggaactg atatatctga tcatctgtta ttacccgata
     1621 ccccagttga gcaagttttt ctatcccatc agcagctata cggaaagttt ccaatatttc
     1681 gtcatgcaga attacgaaaa ggtgaaaaac gtagaggaat ttgcacacct gggaggctat
     1741 accactacca cttttcgccg tttattcaag aacatgtatg gcgtacctgt atacgaatgg
     1801 attctgagca agaaaagaga aggcatcctg gaagacctcc agcataccaa acaacggatc
     1861 accgagatca gtaatcgtta cggattcgac tctttatcac attttgcaca tttctgcaaa
     1921 gcttcctttg gagactctcc acgtgccctt cgtacacgtg cagccagagg tgaaaaaatt
     1981 actgctttaa aaacagaata gaaaccgctc tttttacccg ataacggaca aagcttcatc
     2041 cgaatcccct tctcattctt cggatcagtc ggatacttct cccacgtaaa tggatttcaa
     2101 tcttccatct tccaccctcc ggacaagagc tggaatacaa tacatcatgc tgatatccaa
     2161 atgtatataa ctatatttct atctatatca cttagagtat tttatttttc ttgctatctt
     2221 tagtgaaaat agtcttttct ttatctcgtc ctgtatatct gtgcccatga gcccagatag
     2281 caaggctcac ataaacatat cagaaggtac ggtaatactc ttatttacaa agtattataa
     2341 atgatgtcca tttgacttgt tttcttctta attcatgcac agaaaagaga attagagaaa
     2401 acctcggaaa acgaccaatt aaatataagc atgataacga ctccaaaagc taacttctta
     2461 aagacaaaga ttttactatt ctaacagatt cacgacaaat cctttatacc cccaaccgat
     2521 cgtcccgttt accccatcct ctccggacat tcaggattaa agaattattt ctttaattct
     2581 ttggttaatc aatgtatttc gtgtactttt gcacaatgag aaagaaggct cgtaaaacag
     2641 aaattatagt tctaacaatt aaataattta aaatcaatca tttatgtggt taagtaattc
     2701 atctgtagga aggaaagtgg tgatgagcgt taccggtatc gcccttgtcc tgtttctaac
     2761 gtttcacatg gcgatgaacc ttgttgcgat catctcggct gagggttaca acttggtttg
     2821 tgagttcctg ggagcaaact ggtatgcgtt ggtagctacg ctgggcctgg ctgccctctt
     2881 cgtgattcac attatctacg ctttctggct gacaatacag aatcgcgcag cacgtggtag
     2941 cgaacgttac gccgtagttg acaaacctaa aaccgtggaa tgggcatcac aaaacatgtt
     3001 ggtgctgggt atcatcgtta tcttaggttt gggccttcac ctctttaact tctgggctaa
     3061 aatgcagtta cctgaattgg tgcacaacat gggaggagta gcagacacaa cttatgctgc
     3121 tgatggtgtt tatcacatca tgaacacttt ctctaaccct gtatatgtag tgctgtacct
     3181 cgtttggctg ggcgcccttt ggttccacct gactcatggt ttctggagct ctatgcaatc
     3241 tttgggctgg aacaacaaga tttggatcaa ccgctggaaa tgcatctcca acatctattc
     3301 aaccatcgtt gttgtatgct ttgctctggt agtagtcgta ttcttcgtta aatcgttggc
     3361 atgcggtgct tgctaaattg taaattgtaa atgattaaat tgtaaatagc attatgacta
     3421 agatagattc aaaaattcct gaaggccagc tcgccgaaaa atggagtaac tataaggctc
     3481 atcaaaaact tgttaaccct gccaacaaac gtcgccttga cattatcgtt gtaggtaccg
     3541 gacttgccgg agcatctgct gccgcttctc taggcgaaat gggtttcaga gtattcaatt
     3601 tctgtattca ggattcaccc cgccgtgctc actctattgc agcacagggt ggtatcaacg
     3661 cagctaaaaa ctatcaaaat gatggtgact cggtttaccg tcttttctac gatacaatca
     3721 aaggcggtga ctaccgtgca cgcgaagcca acgtttaccg tctggctgag gtatcaaacg
     3781 ctatcatcga ccaatgcgta gcacagggtg tacctttcgc acgcgattac ggtggcacac
     3841 ttgacaaccg ttcattcggt ggtgcacagg tatcccgtac gttctatgcc cgcggccaga
     3901 ccggacagca gctgttgctg ggcgcttatt cagcattgag ccgtcaggta caaaaaggta
     3961 ctgttaaact ttacactcgt tacgaaatgc tcgacctcgt tgtaattgaa ggacgtgcgc
     4021 gcggtatcat tgcccgtaac ctcgtaaccg gtgaaatcga acgtttcgct gctcacgctg
     4081 tagttatcgg tacaggtggt tacggaaacg cattcttcct ttctaccaac gctatgggtt
     4141 ccaacggttc agttgccatc cagtgctata agaaaggtgc ttattttgcc aatccttgtt
     4201 tcgctcagat tcacccgact tgtatccccg tacacggtga caannnnnnn nnnnnnnnnn
     4261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4321 nnnnnnnnnn nnnnnnnnng gcactaaaaa gccgaccgaa attcctgatg aagaccgtga
     4381 cttctatctg gaacgccgtt acccggcatt cggtaacctt gttccgcgtg acgttgcttc
     4441 acgtgcagcc aaagaacgtt gtgatgccgg tttcggtgtg aacaataccg gtttggccgt
     4501 cttcctcgat ttcaaatatg ctatcgatcg tctgggtgag gacgtggttc gtgcccgtta
     4561 tggtaacctc ttcgacatgt acgaagaaat cactgacgag aacccgtaca agactccgat
     4621 gatgatattc cccgctatcc actacaccat gggtggtatc tgggttgatt atgaattgat
     4681 gacttctatc ccgggtctgt tcgctatcgg tgaagccaac ttctccgacc acggtgctaa
     4741 ccgcttgggt gcatctgcat tgatgcaggg tctggctgac ggatacttcg tattgcctta
     4801 cactatccag aactacctgg ccgatcagat tcaggttccg cgcttctcta ccgacctgcc
     4861 ggaatttgct gcagccgaaa aggaagtgaa agataagatc cagaagatca aagccgtaaa
     4921 cggaaaacac tctgttgact ctatccacaa gaaactgggt cacatcatgt gggacttcgt
     4981 aggtatggcc cgtacaaaag aatctctgca gaaagccctg acaggcattg aagaggtgaa
     5041 gaaagatttc tggaccaacg ttcgcatccc gggtgatgta aacgaactga acgtagaact
     5101 ggaaaaagca cttcgtctga tcgacttcat tgaagtaggt atgctgatgg ctcgcgacgg
     5161 tttgaaccgt gaagaatctt gcggtggaca cttccgtacc gaataccaga ccccggaagg
     5221 tgaagcgtta cgtgacgata agaacttctc atacgtagct tgctggaaat acaccggtga
     5281 aaattcagaa ccggagttga tcaaagaaga tttgaactac cagttcgtaa aagttcagac
     5341 tcgtaactac aagtcataat tcggctaatc aattaaagga aaacaaaaat ggataaaaat
     5401 atatcattca cactgaaggt atggcgccag aaaggcccga aagcaaaagg tgcttttgaa
     5461 acatatcaaa tgaaagatat cccgggcgat acgtcgttcc tcgaaatgct ggatatcctg
     5521 aacgaacaga ttattaatga cggtggcgaa cctatcgtat tcgaccatga ctgccgcgaa
     5581 ggtatctgcg gtatgtgttc tctttacatc aacggacacc cgcacggacc tgcgacaggt
     5641 gctactacct gccagatgta tatgcgtcgc ttcaaagatg gagacaccat cacagttgaa
     5701 ccttggcgtt ctgccggttt cccggtaatc cgtgacttga tggttgaccg ttcggcttat
     5761 gacaagatca tgcaggccgg tggttacgta agcgtaaaca caggtgctcc tcaggatgcc
     5821 aacgctatcc ttatctctaa ggatatcgcc gacgaggcta tggatgccgc tgcatgtatc
     5881 ggttgcggtg cttgtgtagc tgcttgtaag aatggttctg ccatgttgtt cgtatcagct
     5941 aaggtcagcc agctgaacct ccttccacaa ggaaaagtag aagcagcacg ccgtgcaaaa
     6001 gctatgcttt ctaagatgga cgaactggga ttcggtaact gtacaaacac acgtgcttgt
     6061 gaagcagagt gtccgaagaa catttcaatc agcaacatcg ctcgtttgaa ccgcgatttc
     6121 atcatcgcaa aactgaaaga ctaagcacaa cttagcattt gattaataag taggaaaatt
     6181 ccccaccggt atcggtgggg aatttttgta tatggagagc agtgttatct cttacagcgc
     6241 ttacgatacc aaatgataaa gccggtcaca ggaagtgaag cacccgtcag gctcgcaagg
     6301 aacattataa ttttaccagg aagcccccag atgcgcccgt catgaatctc cagattcata
     6361 cgacggaact tatcggcggg agaggcctcg gtatatttac cggcataagg accggctcct
     6421 ttcaaagaaa ccagtgtata ccggtcaaaa aacaaattat cggtacggta gtaagaccct
     6481 cttttatgta caacactgac ccggtaaaca ccatcggctt gtccgggtaa agcaaaataa
     6541 aaggtcttgg cagcaggttc ttcaagccgt agctgagtat aaagtctgtc caaagggttt
     6601 gtcacacgat tgacaacctg caatgtatcg gataccggta aaacgtaggg cttcaactct
     6661 tcaccacccg aagtgatgct gtacacgcct ctgctaaacc aattcaggct aaatatcaat
     6721 ccggtaaaac ataatacagc cagcaccaat gcagcataaa aacccgcaac attatgcagg
     6781 tcgaagttaa gccttgaaaa ggtaaagggg cgtttcagag tcaaccgttg cacaagtgcc
     6841 ttgcgtgtcc agcttctggg ccaccaaagt atcactcccg ttatcagggt gatgaggaaa
     6901 atcaatacac tgtaaccaac aatcggactc ccgatctccc tggggagcca taaagtgcga
     6961 tgcccgctaa gcaccaaccg gaagaaatcg aaatcaccgt tatgattcac taccgacttc
     7021 aatacctgtc cgctatacgg attgataaaa acagtactca tccctgcttc cggctgatag
     7081 tagtccaccc aggccgcatc cgatctttca ccgtaagtga tggctgtggc cgaagctcct
     7141 cccatgacag aatccgctat cgcaagtaag cgggaaggcg gcaaaaactc tttctccaat
     7201 ggagctacaa agcgccaagg ttgtgtggca tcggtaattt cgtctttaaa tgcatacatg
     7261 cagccggtga tgcaaactat gaataccaca atacccgaaa gcaatccaag ccataaatga
     7321 agtttcgcac aagccttccg aaaagtctta ttcatctctt atcaatccag acggaagaaa
     7381 ccgccgacaa acgtggttga aactttagct cccctgaccg cagtagccgc ctgaggatct
     7441 acctgataaa tgtaagtacc ctctgaagta gtgaccggac gataaacata acctccgtct
     7501 accagagcgg caaaacgccg tccgccatct ccgttatgca ccggaatctc tttaatgtca
     7561 cgtaccgttt tattattaag atcgataatg cagcatttca aactcttatc tccccaacgg
     7621 tcggcggatg tctgcggact gatggtgctg acctcggcaa ataccagacc attaccgata
     7681 tatttgatat gggcaggttt caatcctccc gaaaccgtct caaagtcaaa atagtaatca
     7741 tcaaaatgcg tctcaccttt agggatacga aggaaagcag cattcttggt actttgtgag
     7801 aatccgttgg caatggcaga attagacatg atgtacatat cgccggactc taccttaaaa
     7861 ataccgttaa atgcattcca cgaaccggca ggaccggtac gcgtatcttt catcaatgtc
     7921 ttaaactgca tatccggata agagtatacc gcaacaaaag tagtatcggt atataaagtc
     7981 tcaaaagtgg aagggttcat cggaaaataa gtaacgtaca cattaccttc actataacac
     8041 atacccgtga tactcggcca ttcgagttga ttcagcggaa ataccggagc tttgacctga
     8101 gaagtgatag aaacatcact gatatttacg gtatataagg tcatttggtc cccactctcc
     8161 ttattagccg gaagttcaag gccgatcatg ttctgcccgt ccatttgtgt aaacgcattc
     8221 agcgaactgt taaagacaaa gtctccacgc tccgtcagat agccgtttgc atcacgtaca
     8281 attccggttg cactggtcag tcccagtccg ccaatactga acaccgtttg tccggcctgt
     8341 tcataatcac gatatccgtt ttgctcgata cctttggcca ccgcattgat tgttccggac
     8401 atcaattcgg gtgcagtaac cacataataa gtggtagtcc cattggaatt gatacccagg
     8461 ctgagtacat agggagcaaa aggggtttcc tcatttccca atccttcttc ttcacatgcc
     8521 gtgacaccca ataaaaggca ggcagcaagg agatacatat aaattcgata cattgtaatc
     8581 atcagacttt tttatttact aaagaaatat ctcagtttca cattaaaggc acgcccgggt
     8641 ttctgcaagc ggtagttatc atacagcttt tgattggtca gattggtaca ctccacaacc
     8701 acactatact ttccgttgtc cattgaatac cccaatgcca gatcgtgtga gaactgttcg
     8761 gggattactt ttttagagct ttttgcaccc aagcccggga acgaaagata atacgaatga
     8821 atataattaa gattatagtc aaacgtcagc acagagtttc tccaaatcaa atcgtgaaaa
     8881 cgaacccctg catcggcatt agcaaacaaa taagggatgt tcggcaaacg ctctttatag
     8941 gtaatattct ctgtgatacc ttcgccgaca aagctgtcct tcgtcttctc atatcgctgc
     9001 cggtcggtaa tgtcctgata agtaaaaccg gctcccgtat ggaacagatc tttatagtta
     9061 tatctgacag cagcctcaac accctttgtc aacaccttac ccagattctc gtaaccggta
     9121 gtcggattac tggtcaggct gacccctttc aggataaagt ctgtcgtata acgataaatg
     9181 aagtttccat cagccgaaag ttgatgggcc ccgaaagttt gaatgaagct caaccccaga
     9241 ttcaaattcc ggctgctttc cggttttaaa tccggattcc gctgctgaat caacccgtcc
     9301 ccaaacattt cgatactttc cggcaaacga taggcatgct cgtaagagaa cttagcctgc
     9361 aaagagggta agatataata agtagccgcc gcaccgtatc cgaaattggt tttatgatcc
     9421 cgcacttttt cccaacgggc attctctgta tattcatcca accgcttata ggtagaactg
     9481 tacaacttat acatctttcc gaatacattg gcattccaac gatcatagcg gatctgccat
     9541 cccaagcctg tgatattctt agtcagttgc tgaggtacat tgttgttttc atcatccggc
     9601 cgtactttat cattcatggt tctccgcata gcagaaacca cgtggttcag tatcaatgat
     9661 tggtgaccgt cgatcacgta actgatgttt ccgtttccta accattcgcg gttctttatc
     9721 ttggaatccg tataataccc ttctcctgca gaagtagacg gaacggattc tcccaaccag
     9781 ttgtaacggc gggcgatggt atccacattg aaagtattta cagaattata cgttccgtaa
     9841 agtgacagcg aaagtccgtc aagaaacaga tcgtctttct tataacgaat agaagggatc
     9901 acagattcac tcttcatttt tacgccaccg taaacggcat ccatcgtagc accagtctgt
     9961 acatctttat cattcttcga aagaataatg cctgcaagca gatagtcggc ataaggctta
    10021 ttggttattc ccgtctccag gcggatacct cctgaccggt aggcatcatt aaagcgcttt
    10081 acccaccgct cgtctatctt cttattggta gccagatcga tgatgggcac aaacacttta
    10141 taatcattgt cggaatagtt atagaaagca ttggcacgca ccgtgaaacc tgttttcaga
    10201 tgggtatagg ctccattcac cgagacttta tgagtattga aagagccaaa agaataggtc
    10261 gcatccagat aattggcatc tctacggctg acgatattca ccgctcctcc caaggcatcg
    10321 gcacccagat ttacaggtaa taccccttta tatacctcta cacgctcagc catgttagcc
    10381 gagatattag cgaggttaaa agacgatccg aaattatcca tcggtattcc gtccaaaaag
    10441 aatttcacct gattgcccga aaatccgttc aggctgaaat tatagttaga ccccatacca
    10501 ccttcctcac ggatacggac acttgacaca ttgttcaata atttgttgag aggtgcagcg
    10561 ctattatacg ctttcttgat gtcgagtacc gatatggcat acgcctgctc ctgctgccgg
    10621 cgagcttcag attttccaat cacctgtact tcttccagct cttccgcctg ggtatcgatc
    10681 tctatgtccg gaatccggtt cacttttccg gcagtcacat gtatcggcac ctttttagtt
    10741 ttcactccta tgcccgatac aactatcgtc tgactgcccg ccggcacatc attgatatga
    10801 taaactccat tctcgttggt atatccgcca atataaacac cttcaatggc aactgcaacc
    10861 ggatagtaag gttgcttctg ttggtcgacg attcgacctg tcactatacc tttactttgt
    10921 tgttgctgtt cgccggcatg cataagaacg gctgacagca tagaaaaaag acagaataaa
    10981 gctactctgt acaacacttt gtggttcatt aatcactctg tttaattagt ccgcaaaggt
    11041 acgtatatcg acaccggacg acaatcacca tatttaggta ttcaccgaaa ctccgatacc
    11101 taaatacaat gataaaaaaa tctctcttcc agaggcctgt ctcattcgga tgaacgcttc
    11161 aatcgaatgc tgcgtggcga ggtaccaaat gactttttac agaagtttga gaaatgcggt
    11221 aaagattcga acccgaattt ataacagatt tcagagatgg tagcctctgt attctgaagt
    11281 tcgtaaatga tctcctcttt gcggcggcta agcatccact catacaccgg ctcatgaaaa
    11341 acattatcga aaatcctcct gaatgtagtc tggctatatc ctccaagttt agcaaactct
    11401 tcaacagtct tcaccttctt atagttctga tatacaaagc actcaaacga agaagcatat
    11461 tttgagagag gatgtaccaa ggaagccagg tcataatccg aataaaaata accgagtatg
    11521 aaagcaagct ctttccgctt taatgataag agatcccgac aaatcttctt ttcgctcaga
    11581 taagtacgtg cagactcaag aaaatgttga agttcgggaa taatgggtaa gggtgaggga
    11641 attaacggag gatcagtctc cttcatgata cgattatacc ggatatcaca aaacaattca
    11701 ggttgattaa actgataata gatacattcc acatcggtca tggccagcat ttctattttc
    11761 gaactgatgg gctgaagcat aaattctccg gctttaagca ttgttccggc atactcccgg
    11821 ctattcacca gcatttctcc cttgataaga aacaaaatga aattctcctc acatttttgt
    11881 gcaggataat ggaaaccacg tctatggtaa acatggaaaa tggcattagg aactgacttt
    11941 ttacagttct gacacatcat gggatctcca caaacggagc tgggcatata tacgggtgtg
    12001 tttgtttgta tgtttacgac aaatgtaaga gaattattta gaaagacaat aaaagaagga
    12061 ataaaaaaat agccctactt gaacagggct atcaaatgca tcatttatta taatattatg
    12121 gatagcccca tatttgaaaa caggattcaa gttttatact tgaatcctga agttttctat
    12181 ttacacaaaa tgatggacag tatcgaatac tacttaggag tatcagtgaa atcccagcta
    12241 tcagcaactg aaccggtaat agacatcttc tcaacgcctt ttaacgtcaa tacgtaagca
    12301 acactttgtc cggcagtcca agttccatcg gcaaatgtaa tttcttccgg agtagttgtt
    12361 ttatcacaca atatcgcacc accagcctca gctttgtagt aaatttcgaa tgtaacgcca
    12421 gttaaatctt gaggaataag catggctgtg taatctgctc caaccaaagt ctcgttcgca
    12481 gtgccaccgt tatctgctcc tgtaatagaa agtgccttag taggttcgac agtatatgct
    12541 gtattagctg taacatcgct aggaatagtc catgtaccta atgttgtctc actagtagta
    12601 gaagtagccc cataagtata cacacctttt ttcttggcat taataactat tttatttaaa
    12661 gtgtaagtaa caccacttcc ttctcctttt attttaaaac caaccttcgt caacgcgtgt
    12721 ttaaaattta aagcaaccgc tnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nncacagcat ctttcacagt ataggtcagt
    12841 gtaggcgctg ttttagcagc agctgctccc caagaaaact gttctgtagt gttaggtgaa
    12901 aaagcaaaga aacttacttg atctgttgcc ggccaataga atacagagct accactgccc
    12961 catgtgcttt cttttaattc aaattcagtt ccagatatca gcgcattaac ttctgtagca
    13021 tcagcaaatg ccccagtagt agaataggca tacgccgtaa actttgtaaa agctgagttc
    13081 actaaagtcg tagctcttgt tgtcttactt actgccgtat tgaaactaat ttccaccggc
    13141 tgtacagcct tttcaatctc ttcattctgt gagcaacccg taattgccat tgcagcgact
    13201 gctgcgaata aaatcttctt cataatagta tgttttttta agttattaat atttttattt
    13261 gtatgtattt cttttttctt atccaacagg caactctaca ttcgtttcgt cgtcccaatc
    13321 tcctacatca ccaccaatgc caccacctcc acttggagga gtttccacat catctacttt
    13381 tatttcatct tctatttcaa cttcaaccaa tgccggcggt tttgtttcct ctccttctcc
    13441 tccttcacca ccgccggtag gttcttgtac agcttccgtt atattaatct taacctcctg
    13501 taccgaattg tccaccttaa taatcatcag gttcatcatc accggaagtt ttatttctaa
    13561 acgggtaata atagcttccg gtaatccaaa agtggtaaat accccttcta tcttcccggc
    13621 tttcacattc aggtcaatat taatcggata gtcatcgcac atagcataag cttttcctaa
    13681 aaaataatga tctgccatcc caccaatact ccctatcacg tttgaaacat tacttaatcc
    13741 ctgcactttg atactaaagg agtaagttct tatcaccaat tttggtttca gcttcagaat
    13801 caatgtctct tcactattct gtatatccaa atcatctata tttaccacat aaagcggatc
    13861 cggtccccaa accatctttt ctgtacctgc aatacccaat ttacaaaaat tggtataagc
    13921 ctgaatggtt tcataagatt cctctccacg aattaagacc gtttcagtat cgtaattgta
    13981 aataacaaca gcgtagtgtc ccgaaggaac ttttacttcc ccacctgtta ccgacaaata
    14041 cgtatctatc tttctacctt tttcgtcttt cggatagaaa ataatccga
//
