LOCUS       c00102_gnlPro..         4389 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ILNKOMKB_102.
ACCESSION   c00102_gnlPro..
VERSION     c00102_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 20:53:41
            Original ID  :: gnl|Prokka|ILNKOMKB_102
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4389
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..612
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_1"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.1e-49, bitscore:
                     155.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="ELHPMGDTLSMGEVVRAVSDATNHEAILVTDVGQNQMMSARYFKY
                     SKDRSMITSGGLGTMGFGLPAAIGATFGRPDRTVCVFMGDGGLQMNIQELGTIMEQKAP
                     VKIIVLNNNFLGNVRQWQAMFFNRKYSFTPMLNPDYIKIASAYDIPAKRVFTREELADA
                     IDEMIATDGPFLLEACVIEEGNVLPMTPPGGSVNQMLLEC"
     protocluster    1..4389
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:3658]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1..3658
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..4389
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4389
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             626..1186
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_2"
                     /sec_met_domain="ALS_ss_C (E-value: 2e-19, bitscore: 58.4,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKTLYTLIVHSENFAGLLNQVTAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTDKDTIEKVVKQIEKKIDVLQAHYFTEDEIYFHEIALYKVSMPEFQSQPE
                     ASKVIRRYNARIVEVNPVFAIVEKNGISEEITSLYEELSALNCVLQFVRSGRVAITTSC
                     FERVNEFLADRETKYNLSKKEEK"
     CDS             1187..1930
                     /locus_tag="ctg102_3"
                     /transl_table=11
                     /translation="MSDNKKIGSYKFIAEPFHVDFNGRLTMGVLGNHLLNCAGFHASER
                     GFGIATLNEDNYTWVLSRLAIDLEEMPYQYEEFTVQTWVENVYRLFTDRNFAIIDKDGK
                     KIGYARSVWAMINLNTRKPADLLTLHGGSIVDYVCDEPCPIEKPSRIKVATDQPCAKLT
                     AKYSDIDINGHVNSIRYIEHILDLFPIDLYKSKRIQRFEMAYVAESYYGDELSFFEEEV
                     SENEYHVEIKKNGSEVVCRAKVKFV"
     CDS             1948..2532
                     /locus_tag="ctg102_4"
                     /transl_table=11
                     /translation="MKKIVFLLLLCVACCMNAQEFHLIPKVGLNLANTTGEVDSKVRPG
                     LNIGLGGDVMLTERFGIETGVYYSMQGSKYKGGGVSYTDKLDYINVPVYAKEFIYKGLY
                     VFGGPQFSFNVNSENKSSSDYGTTVIGMNVIRKFDCGVGLGAGYQFERGLLISLNYNIG
                     LINVNKSWASDSNPKANNSVVQLNVGWRFAL"
     CDS             2615..3658
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_5"
                     /sec_met_domain="IlvN (E-value: 4.8e-46, bitscore: 145.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 4.9e-41, bitscore: 129.1,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGVTENVVTREEFPLEKAREVLKNETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRPGKTYEKAVADGWVPGETLFGIEEACEKGTIIMCLLSDAAVMS
                     VWPTIKPYLTAGKALYFSHGFAITWSDRTGVVPQKDIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAIYQDATGRAMERTIALGIGVGSGYLFETTFVREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     PFHDAIKPVVQKLYNSVKTGNEAQISIDSNSKPDYREKLEAELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             3860..4387
                     /locus_tag="ctg102_6"
                     /transl_table=11
                     /translation="MKNRIYTMKGMLATLLGAFLLGYAVTGCIDEKDHYKPDDKTSGVP
                     NSFDFATTQDVQLDLKYDVPVKDYQVLFELYFENPLTTDAEGQVVKRTDITPKVVRMTD
                     GTGKYRAKETVPAYGEEVYIYTSYIGVPMLYKTKVAGNTITADINWDTAAEESVQTRAE
                     GEYQTVPQGFYTL"
ORIGIN
        1 gaattgcatc cgatgggaga tacactttcg atgggggaag tggtgcgtgc ggtaagcgat
       61 gcgaccaatc atgaagcgat attggtaacc gatgtcggtc aaaaccagat gatgtctgcc
      121 cgatacttta aatattcaaa agaccggagt atgattactt ccggaggact tggtaccatg
      181 ggattcgggt tgccggctgc tatcggtgca acctttggcc gaccggaccg tacggtttgt
      241 gtatttatgg gtgacggtgg tctgcaaatg aacattcagg agttgggaac cattatggaa
      301 cagaaggcac cggttaaaat tatcgtatta aacaataatt tcctgggcaa tgtacgccaa
      361 tggcaggcaa tgttcttcaa ccgtaaatac tcgttcacac ccatgctgaa tcccgattat
      421 attaagattg cttctgctta tgatataccg gccaaaagag tctttacccg tgaagaactg
      481 gctgatgcga ttgacgaaat gattgcgaca gacggtccgt tcctgttgga agcttgtgtg
      541 attgaagagg gaaatgtgtt gccgatgacc cctccgggag gttcagttaa ccagatgttg
      601 ttggaatgct aataagttag gaattatgga taagacatta tatacattaa ttgttcattc
      661 agagaacttt gccggattgt tgaatcaggt tacggcagta tttacccgtc ggcagattaa
      721 tatagaaagc ctgaatgttt cggcttcatc tatcaagggg gtgcataaat atactattac
      781 ggcttggacc gataaagata cgatagagaa ggttgtcaaa cagattgaga agaagatcga
      841 tgtgcttcag gcacattatt tcactgaaga tgaaatctat tttcatgaaa tagctcttta
      901 taaggtgtct atgcccgaat ttcagtcaca gccggaagct tcgaaggtga ttcgtcgcta
      961 taatgcacgg attgtggaag tgaatccggt atttgccatc gtcgagaaaa atggaatcag
     1021 tgaagaaatt acttctctct acgaagagtt gagtgcattg aattgtgtgt tgcaatttgt
     1081 gcgttcggga cgtgtggcaa tcactaccag ttgctttgaa cgtgtgaacg agtttctggc
     1141 agatcgtgag accaaatata acttaagcaa gaaagaggaa aagtgaatga gtgacaataa
     1201 gaagataggg agttataagt ttattgcgga gccttttcat gtagacttca acggacgttt
     1261 gacaatgggg gtgcttggca accatctgtt gaactgtgcc ggctttcatg ccagtgaacg
     1321 cggctttgga atcgctacat tgaatgagga caattataca tgggtattgt ctcgtctggc
     1381 catcgatctg gaagagatgc cttatcaata tgaggagttt actgtacaga catgggtgga
     1441 gaatgtatat cgtcttttta ctgatcgtaa ttttgccatt atagacaagg atggcaagaa
     1501 gatcggatat gcccgttcgg tatgggccat gattaattta aatacccgca agccggctga
     1561 tttgctgacg ttgcatggcg gtagtattgt ggactatgta tgtgacgaac cttgtccgat
     1621 cgaaaagcct tcgcgtatca aagtggctac tgaccaacct tgtgctaagt tgacagctaa
     1681 atacagcgat atcgacatca atggtcatgt gaacagcatt cgttatatag aacatatcct
     1741 cgatttgttt ccgatcgatt tgtataaatc gaaacggatt cagcgatttg aaatggccta
     1801 tgtggcagaa agttattatg gcgacgagct ttcttttttt gaagaggaag taagtgagaa
     1861 tgaatatcac gtcgagatta agaaaaacgg cagtgaagtt gtatgccggg caaaagtgaa
     1921 gtttgtgtag tttaaaatgt gattaaaatg aagaagattg tttttctttt gctgctctgt
     1981 gttgcttgct gcatgaatgc acaggagttt catctgattc cgaaggtcgg tttgaatctg
     2041 gcaaatacta ccggggaggt ggattctaaa gtgcgtcccg gactcaatat cggtctggga
     2101 ggtgatgtca tgctgaccga acggtttgga atagaaacag gagtgtatta ctccatgcag
     2161 ggaagcaaat ataaaggggg cggagtctct tatacggata aactggatta tatcaatgtt
     2221 ccggtatatg cgaaagaatt tatatataag gggctgtatg tgtttggagg gccgcagttc
     2281 agtttcaatg tgaactcaga gaacaaatca tcctccgact atggtaccac agtcataggc
     2341 atgaatgtga ttcgcaagtt tgattgtgga gtggggcttg gagccggtta tcagtttgaa
     2401 cgtggtctgc tgatctctct aaactataac atcggactga ttaacgtaaa caaatcttgg
     2461 gcaagcgact ctaatcctaa agcaaacaat agtgtggtcc agctaaatgt cggttggcgt
     2521 tttgcactgt aagataaaga atataagttt aattattaat aatcggtttt gttttcgtcc
     2581 gaacggaaca agacttttaa aacaaaaaag aaaaatggca caattgaatt ttggcggtgt
     2641 tacggaaaat gtagtaaccc gtgaagaatt tcctttggaa aaagctcgtg aggtattgaa
     2701 gaatgaaaca atcgctgtta tcggttacgg tgtgcaggga ccgggtcaat cactgaacct
     2761 gcgcgataat ggcttcaatg taatcgttgg tcagcgtccg ggaaaaacat atgaaaaagc
     2821 agtggcagac ggctgggttc cgggtgaaac actgttcggc atcgaagagg catgcgagaa
     2881 aggtactatt attatgtgtc tgttgtcaga tgcagccgta atgtctgtat ggcctactat
     2941 caaaccttac ctgactgccg ggaaagcact ctatttctct cacggtttcg caattacatg
     3001 gagcgatcgc accggtgttg ttccacagaa agatatcgat gtcattatgg tcgctccgaa
     3061 gggttcgggt acttcactcc gtacgatgtt ccttgaaggt cgcggactga actcttcgta
     3121 tgccatctat caggatgcta ccggcagagc tatggagaga accatcgcat tgggtatcgg
     3181 cgtaggttcc ggatatctgt ttgaaacgac ttttgtccgt gaagctactt ccgacctgac
     3241 aggtgaacgt ggttcgctga tgggagctat acaaggtttg ctgttggctc agtatgaggt
     3301 tttgcgtgag aacggtcata ctccatctga ggcatttaac gaaacggttg aggagttaac
     3361 tcagtcattg atgccgctgt ttgctaagaa tggtatggac tggatgtatg ccaactgctc
     3421 gactacggct cagcgtggtg ctcttgactg gatgggcccg ttccacgatg ctattaaacc
     3481 cgttgttcag aaattatata atagtgtaaa gaccggtaac gaggcacaga tctctatcga
     3541 ctctaattca aaaccggatt atcgcgagaa actggaggcc gaactgaagg cattgcgtga
     3601 aagcgaaatg tggcagacag ctgtaaccgt tcgtaaactt cgtccggaga ataattgatc
     3661 tgaatagatt atacaactta tgataaaagg aggaaactgc tgtttcctcc ttttattttg
     3721 cttgtaatta gtgttttgtg tctgagttgt tagaatggta tgttgtagaa tatgaaaaat
     3781 agatagatcg tttggataga taaatcaagt taaatatata tctttgtgcc ctgatcaaac
     3841 aacaaacaat attatcaata tgaaaaatcg tatttataca atgaaaggga tgctggctac
     3901 attactgggt gcttttttac tagggtatgc agtaacaggt tgtattgatg aaaaagatca
     3961 ttataaaccg gacgataaaa catcaggagt gcctaactct tttgattttg cgactactca
     4021 ggatgtccaa ttggatctaa agtatgatgt tcctgtgaaa gattatcagg ttttgtttga
     4081 actctatttt gaaaatccgt tgacgacaga tgccgaaggg caggtggtga aacgtactga
     4141 tatcactccc aaggttgtga gaatgactga tggaaccgga aaatatcgtg ccaaggagac
     4201 ggtaccggcc tatggggagg aggtttatat ctatacttct tatatcggag tgccgatgtt
     4261 gtataagact aaagtagcag ggaatacgat tacagccgat ataaattggg atacggcggc
     4321 agaggagtct gttcagacac gtgccgaagg cgagtatcag acagtgcctc agggatttta
     4381 tactttagg
//
