LOCUS       gnlProkkaPDNOPKAN_1    12151 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PDNOPKAN_1.
ACCESSION   gnlProkkaPDNOPKAN_1
VERSION     gnlProkkaPDNOPKAN_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 06:34:52
            Original ID  :: gnl|Prokka|PDNOPKAN_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 1917286
            Orig. end    :: 1929437
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12151
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:7151]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7151
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..12151
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12151
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(205..408)
                     /locus_tag="ctg1_1812"
                     /transl_table=11
                     /translation="MDEIISFEFSNGSKILDSNIYEYKVGKESVTKIDLPDSNGFVAVH
                     KDNNKTEYIKAPYMKFCTDSHV"
     CDS             complement(546..1232)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1813"
                     /sec_met_domain="Abi (E-value: 2.9e-14, bitscore: 50.7,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLQKNLRFIGNLLIVSVLSVIIVNISSLPVYIYLITANWFTLLVS
                     FSLYAVIIVFLYNIYKTTAELRQFDFRPWRTRLNKRALLLMVIGAVIIVAFAFGHAKLT
                     AVWHITESGNERALDLLLRKNPLAMTLDAVIFGPIAEELSFRGFFFSYVLSDQYLGREY
                     QAATIVINGLLFGYLHSGNSLVPLAYYTLFGMVLGTIYLLSKHDIRVNSVTHMLANLGI
                     LWLVPS"
     CDS             complement(1326..2006)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1814"
                     /sec_met_domain="Abi (E-value: 4.1e-10, bitscore: 37.4,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVHQNVKFIGRLLLASLLAAIVMGLSTAPIDILTLNYNWITVAIF
                     LVVYLFAIYLFYRIYLESVTNNHFKITKITAKPSARQLVVTVLAMVVMLILAAVQVKFV
                     SDAVYPIAENVADLQALSQRSPILMALALGVFAPIFEELIIRGNFFSYALAGRFDQPRY
                     QLVTVIVNGVLFGLLRGGFSWVQLSYYTVMGLVLAATYILSGRDIRVNSVVHVTANLGL
                     MLMA"
     CDS             complement(2093..2761)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1815"
                     /sec_met_domain="Abi (E-value: 1.1e-17, bitscore: 61.7,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVARLLRVFGYVLAGLGLFIFIQLPVLADGYWNWWGERSQQINGG
                     YHWVALVVLTVGVAVVLVRCYHHYFEMPVLVGPFSWSMMGLTALVAVVVVVIQMGISGL
                     LVSPTETQNDEIMALIHSPLGLLTLVCTNIVSPVLEELLFRGIVQNTLRRYLPVLGAIM
                     LTNAVFALGHGYQLASTVGIFITGCGFSWLVLKTKQLSTAMGCHILVNWLVTIINMMWG
                     "
     CDS             complement(2829..3518)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1816"
                     /sec_met_domain="Abi (E-value: 6.9e-16, bitscore: 55.9,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAHSNKQFIINLVIASLISLALVSFSMAPAYLFLIKNNWFMITIG
                     FVIYALEAWGLYWLYRHTARVRHYQVATLKSRVNIAQLGTVIIAMLTMVVLIIVDLKLS
                     AMLNIPETSNSRSLAWMLGEAPLPMIVSVVIFSPICEELIFRGIFFSYALTNQYNHRNY
                     QMIAVVINSLIFASVHVDANWEPWIYYTLMGGILGTTYLLAKRDIRMNILVHMGTNLAV
                     FALAAMS"
     CDS             complement(3608..4984)
                     /locus_tag="ctg1_1817"
                     /transl_table=11
                     /translation="MRKDLLESGEFYGIRFQNFSTLLIIPVTLLLIGTILFSLVAKREI
                     VINGTGTVQPTGTVPVIQATVNSAIKKNYLVEGVRVKKGQKLLVYTNVFNRNKLREDNV
                     SKRQLQRQVIALDHFKDGINTDSDVFPTTDEFGYRELLQSYLKQRQIYLTENQMLAAKS
                     SAASTKKATLTKTAQQVVSNTKTNLDAYQALYNAVANGSKYANSAKYGSVFNEYVAKSK
                     EANNANDKKEVKSATLADIQQQIDTLQDSLSSAKVQLEELQGFDDTKYSVETNNTKLAM
                     LKNDQLSEVAEKRMKAEQDLRTVKADIDSLTTQSKSYTIKATKTGVLHVADNYRGAKYV
                     SSGAEIAKILPIIKQQRRVNVKLYISTADISSVKVKQAIRFKVTRNVPKPIILDGVVTK
                     IGVSPVEESKATFYEVTAAVPITADQAQLLRYGMIGQTAIITGKVTWFDYYKDKVLDNN
                     "
     CDS             complement(5001..7151)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 328.6; E-value:
                     1.2e-99)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1818"
                     /sec_met_domain="Peptidase_C39 (E-value: 6.2e-47, bitscore:
                     156.2, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1096.4,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHWRNYVAQVDEMDCGVAALAMILKNYGSTTSLAYLRNIAKTSLE
                     GTTALGLVKTAEKLGFETKAIQADMSLFDVQDLPLPFIVHVTKNGDLQHFYVVVKTSKT
                     HVVIADPDPTVAVISMSKERFESEWSGVALFFAPKSEYKPVKQDKGSLWGFIPSLLKQR
                     RLVINIVLAAVLITIISICGSYFLQAVIDTYIPNNMHSTLAVVAIGLIVFYTFQAIFTY
                     AQNFLLAVLGQRLSIEIILGYIRHVFELPMSFFATRRTGEIVSRFTDASKIIDALASTI
                     VSLFLDVSIVIIMGAILVIQNMTLFWITLLSLPIYAVVILAFNKSFERLNQKEMESNAI
                     LSSAIIEDLHGIETVKALNGETERYQKIDSEFVDYLRKSLAYLKADTLQQALKLFIQLV
                     LEVVVLWVGANLVIHNQLSVGELMTYNALLAYFVNPLQNIINLQTKLQSAKVANNRLNE
                     VYLVASEFEASRPIHNESQLNGDIKLQGVSYRYGYGENVLDDVNLTIRQHDKVAIVGMS
                     GSGKSTLVKLLIDFYQPNSGDVMLNGFNVKNIDKHTLRTHINYIPQEPYIFSATIEENL
                     RLGNRSGITEKDIAKACQLALIDTDINKMAMQYQTKLDENGNTLSGGQRQRLTIARALL
                     SPAQVLIFDESTSGLDAITEKQLIDNLVAMTDKTIIFIAHRLSIAKRTNHIIVLHDGRV
                     AEEGTHAALLNEHGYYYDLINS"
     CDS             7417..7587
                     /locus_tag="ctg1_1819"
                     /transl_table=11
                     /translation="MLQFEKLQYSRLPQKKLAKISGGFNRGGYNFGKSVRHVVDAIGSV
                     AGIRGILKSIR"
     CDS             7612..7770
                     /locus_tag="ctg1_1820"
                     /transl_table=11
                     /translation="MKKFLVLRDRELNAISGGVFHAYSARGVRNNYKSAVGPADWVISA
                     VRGFIHG"
     CDS             7869..8642
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1821"
                     /sec_met_domain="Abi (E-value: 1.2e-13, bitscore: 48.8,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLIKVIITAIYYLIVLFLMNPLTDIMGIKDGPFQFILTESIILI
                     AVIILNRRYVKQPIHWLPVNIMSILRKNSLPLSLAIIFLLIFFRNHMYQFLISLLLSLI
                     VAITEEYAFRGMIFRTLLALNLKKFATLQATIASMMTASLIFAAMHLVNLLSQPVWSVL
                     CQVLYVIGLGILLAAIYLKTGSLLAAISVHWLIDFSSFYSQGIDPTQSPINGPMEALLK
                     GLFLNILFIGIATFILSSKHWKLLSILNIEDKIDE"
     CDS             complement(8936..9679)
                     /locus_tag="ctg1_1822"
                     /transl_table=11
                     /translation="MFPIYLYEDNAEQRDNYRKTINNTIMINEFAMALRAATDDQKIIL
                     ADLNQQQDGLFFLDMEIGEDKQAGLELASRIRAAIPLAKIVFITTHDELSFVTLERRIA
                     PLDYILKDQSADLITQRIIKDINVVQNELKKTNSQRKDVFNYKLGTRYFSLALDDVILL
                     STSKLRPGSVQLHAINKVAEFPGNLNALEEKYPQFFRCDKSSLVNLNHLRSFDYKEKEL
                     LLDGEIRCKASFRKSRELNKLLRDN"
     CDS             complement(9680..11020)
                     /locus_tag="ctg1_1823"
                     /transl_table=11
                     /translation="MLDFGVVDTFYQGFTSVLVVLLWYYFLSGLFNWKSVLKILVLTFF
                     WGVLSVFVADFILLIMVLINFASQFIQKKSLNYDKSGILLLVVIIQVLIGNIAMFLGRM
                     SVRGLYNVSNLMGVQYYTHEVLIIYVIFVIIINYAILFFYRRYCHKIVSVNRKIKELNL
                     SKSLFELILIFYVAIESIMLISLNENITATIQLTLITSFIVMLLMMLWQMFFFIRSYMK
                     KQEASYQAKQNTQLNEYLKSVEQQYLELRRFKHDYKNVMLALQDSISSGSSSEQLPYFK
                     ELIAQSAIDTSLDSGKIAKIQHVGNETLRGLIVQKFFDAQTKGIELSLELDQSEFIIQH
                     NLVDVVRIVGNLLDNAIDAAKSTPDKQVTCAFNSLHETKEISVRNSTNKKLDVNKMFEL
                     GASTKGSQRGFGLSNVQQLVDKQKNFFLDVDSKNDRVIITLTILEEE"
     CDS             complement(11038..11205)
                     /locus_tag="ctg1_1824"
                     /transl_table=11
                     /translation="MNKNSMSFDKVVGKSLDVEQLQKVSGGKFQSVSLMYGNNVSRKTL
                     TKFFKSLIKR"
ORIGIN
        1 cgtcacgagc gatgcaccac ttgacattgc tcagcatcgg tgatgtctcc ccactaattg
       61 cccaattgga cccgacatta tttacgattg aacatcaggt acgagtataa ctgaaattaa
      121 aaaacgactg gaagtagccc agcggtatta cgctagctac ttccagtcgt ttttcgttat
      181 cacgaaacta atgctgggcc atttttaaac atggctatct gtgcaaaatt tcatatatgg
      241 agccttaata tactctgttt tattattatc tttatgaaca gccacaaatc cattgctatc
      301 cggcaagtct attttggtaa cgctttcttt gcctacttta tattcataga tattactatc
      361 taaaattttc gaaccattag agaattcaaa agatataatt tcatccatac ttaccaaact
      421 ccttctaata tcacatatcc atcaattaca gttttcagaa ccaactttgt atttttatca
      481 ccgtattcac aatattctta ctacctgtta ccttgttcac tttagcataa gccaaagtaa
      541 ctattttagc taggaaccaa ccagagtatc cccagatttg ctaacatatg tgtcacgcta
      601 ttcacacgaa tatcatgctt agataatagg tagatggtcc ccagcaccat gccgaacagc
      661 gtgtaatatg ctaatggcac caagctattt ccgctatgca gataaccgaa aagaagccca
      721 ttgataacaa tggtagccgc ttggtactcc cggccaagat attggtctga caagacgtaa
      781 ctaaagaaaa agcccctgaa actcagctcc tcagcgattg gtccaaaaat gacggcatcg
      841 agtgtcatcg ctaacggatt tttccgcaac agtaaatcta atgcacgttc attacccgat
      901 tcagtgatgt gccataccgc cgtcagctta gcatggccaa aagcaaacgc cacgataatg
      961 actgcgccga tcaccatgag tagcaaggcc cgtttattta gccgcgttcg ccacggtcga
     1021 aaatcaaatt gccgcaattc cgcggtcgtc ttatagatgt tgtacaagaa aacgataatc
     1081 acggcatata aactgaagct aactaacagt gtaaaccaat tggccgtaat caagtaaata
     1141 tacacgggta aggaactgat attgacaata atgacactca acacactcac aattagtaaa
     1201 ttaccaataa accgtaaatt cttctgtaac atttcatcca ctccatccaa acaaccgtaa
     1261 ctagaatgtt cactaacggg cttttagatc aacccactca agttacttgc caaatccatc
     1321 tggcctcatg ccattagcat gaggcccaga ttagctgtga cgtgcacgac actgttgact
     1381 cgaatatccc ggccagataa tatgtaggtt gccgcgagta cgagacccat aaccgtatag
     1441 tatgacaatt gcacccaact aaaaccgcca cgcagtagac caaacaacac gccgttaaca
     1501 ataacggtaa ctagttggta tcgtggctga tcgaaacgtc ccgccagcgc ataactgaag
     1561 aaattgccgc gaataattaa ttcctcgaaa atcggtgcaa aaacacccag ggccaatgcc
     1621 atcaatatcg gtgagcgctg agacaatgct tgtaagtcag caacattctc cgcgattgga
     1681 tagacagcgt cactaacaaa tttaacttgc accgctgcca agatcagcat gaccaccatt
     1741 gccagtaccg taaccactaa ctgacgcgcg ctcggcttag cagttatttt cgtaatctta
     1801 aaatgattat tagtaactga ttccagataa attcgataga ataaataaat tgcaaacagg
     1861 tagacgacca agaagatcgc caccgttatc cagttataat tgagtgttaa aatatcgatg
     1921 ggcgccgtac taagacccat cacgattgct gccaataaac tggcaagtag taatctacca
     1981 ataaatttga cgttttgatg taccatgctc cttcacatcc atttcttgat aattatcccc
     2041 aatggtacct aatccacaac ttgcggtttg accggatatc actaactgaa acttatcccc
     2101 acatcatgtt aataattgtg accagccagt tcaccagtat atgacatccc attgcggtac
     2161 tcagttgttt tgttttgagt actaaccatg aaaaaccgca ccctgtaatg aagatgccca
     2221 ccgtactggc taactgataa ccatggccga gcgcgaatac tgcgtttgtc agcataatcg
     2281 cgcccaatac tggcaagtat cgtcgcagcg tattttgaac aattccacgg aaaagtaatt
     2341 cttcgagtac ggggctaacg atgtttgtgc acactaatgt taataacccc aatggactgt
     2401 ggatcagtgc catgatttca tcattttgtg tttcggttgg actgactagc agaccactta
     2461 tccccatttg aatcaccacg accaccactg ccactaaagc agtcagcccc atcattgacc
     2521 aagaaaaagg ccctaccagg actggcatct caaaataatg gtgatagcaa cgtactagta
     2581 cgaccgcaac accaacggtt aaaacgacta atgctaccca atgataaccg ccgttgattt
     2641 gttgcgagcg ttcaccccac caattccaat agccatccgc taacaccggt aattgaatga
     2701 atataaatag ccctaaaccc gctaacacat aaccaaatac cctgagcaat cgagcaacca
     2761 taccaagcct cccaagttat cccctgtgga taaactaatt cttatgtttt aattttttat
     2821 ccacaacatt aactcatagc cgccaacgcg aaaactgcca aattagtccc catgtgcacc
     2881 agaatattca ttctaatatc gcgcttagcc aacaaataag ttgtccccaa gatgcccccc
     2941 attaacgtat aataaatcca cggctcccaa tttgcatcaa catggacact tgcaaatatt
     3001 aagctattaa taacaaccgc gatcatctga taattacggt gattatactg attcgttaac
     3061 gcgtagctga aaaagatacc gcgaaaaatc aattcctcac agatggggga aaatatcacg
     3121 accgaaacaa tcatgggaag cggtgcttca ccgagcatcc atgccaacga cctggaattg
     3181 ctggtctcgg gaatatttag catcgcgctc aatttaagat caacaataat gagcacgacc
     3241 attgtcagca tcgcaataat cacagttcct aattgtgcaa tgttcacccg ggacttcaac
     3301 gtcgcgactt ggtaatgcct aactcgtgct gtatgccgat aaagccaata tagcccccaa
     3361 gcttccaagg catagattac aaaaccaatc gtgatcatga accaattatt cttaattagg
     3421 aaaagatacg ccggtgccat actaaagctc accaatgcta agctgattag actggcaatg
     3481 actaggttaa tgatgaattg tttatttgag tgtgccatta cttacctctt tcgtatgata
     3541 tatgtgcttc tagataactt tactttacca cagtgatatt tagtcagtta gtactgatgg
     3601 accaccatca attattatcc agcaccttat ctttataata atcaaaccaa gtcaccttgc
     3661 ccgtaataat cgccgtttgc ccaatcatcc cgtagcgcag taactgtgcc tgatcggctg
     3721 taatcggaac ggccgctgtc acttcataaa aagtcgcttt actctcctcg actggtgaga
     3781 ccccaatctt tgtgaccaca ccgtccaaaa taattggctt cggtacgttc cgcgtgactt
     3841 tgaatctaat ggcttgcttg actttaacgg aagaaatatc cgccgtcgaa atatatagct
     3901 taacgttcac tcgccgttgt tgcttgatta tcggtaaaat tttagcgatt tcagctcctg
     3961 aactaacgta ctttgcacca cggtaattgt ctgcaacgtg taggacgccg gttttggttg
     4021 ccttgatcgt gtaagatttt gattgtgtcg ttaagctatc aatatctgct ttcacggtcc
     4081 gtaaatcttg ctcagctttc attcgtttct cagcgacttc gcttaactga tcattcttta
     4141 acatggctaa tttggtattg ttagtctcaa cactgtactt cgtatcatca aagccttgta
     4201 attcttctaa ctgcacttta gctgaggaca acgaatcctg aagcgtatct atctgctgtt
     4261 gaatgtctgc taacgttgca gatttaactt cttttttatc gtttgcgttg ttggcctcct
     4321 ttgacttagc gacatactca ttaaaaacag acccatactt ggcactattg gcatacttgc
     4381 taccattagc caccgcattg tataaggctt gataagcatc cagattggtc ttagtatttg
     4441 ataccacttg ttgcgcggtc ttcgttagcg tggctttctt agtactagca gcgctcgatt
     4501 ttgctgccaa catttgattc tccgttaaat agatttgacg ctgttttaaa taactttgca
     4561 atagttctcg gtacccaaat tcatcggtcg ttggaaaaac atcactgtca gtattgatgc
     4621 catctttaaa atgatccaag gctattactt ggcgttgcaa ttgccgtttg ctgacattat
     4681 cttcgcgtaa tttattgcga ttaaaaacgt tagtataaac taatagcttt tgacccttct
     4741 tcactcgcac accttcaact aaataattct ttttgatggc actattgaca gtcgcttgaa
     4801 tcaccggaac cgttccggtc ggttgaacag ttccagtacc attaataaca atctcgcgct
     4861 tagctacgag tgaaaacaga atcgtaccaa ttaacaatag cgtcactgga ataattagta
     4921 atgttgaaaa attttgaaac cgaatcccgt aaaactcgcc actttctagc aggtcttttc
     4981 tcattattca gtttcccccc tcagctattg atcaagtcgt aatagtaacc atgttcattc
     5041 aacaatgccg catgggtccc ctcttcagcg acccgaccat catgcagaac gatgatatga
     5101 ttcgtccgct ttgcaatcga cagccggtgg gcaataaaaa taatcgtctt gtcagtcatt
     5161 gccactaaat tatcgattaa ttgtttctca gtaattgcat ccagtccact cgtcgactca
     5221 tcaaatatca agacttgagc gggagataat aacgctctcg caatcgttaa tcgttgtcgc
     5281 tgaccacctg atagtgtatt accattctca tctagcttag tttggtattg catggccatt
     5341 ttattaatat ctgtatcaat taacgccaat tggcaagcct tcgcaatatc tttctcagta
     5401 ataccgctgc gattacctaa tcttaaattt tcttcaatgg tcgctgaaaa gatgtatggt
     5461 tcctgcggga tgtagttaat atgggtccgc aatgtatgct tatcgatgtt cttaacgttg
     5521 aagccgttca gcatgacatc accactattc ggctgataaa aatcaataag caatttaact
     5581 aacgtggact tgccagagcc actcatcccc acaattgcaa ccttatcatg ttgtcgaatc
     5641 gtcaaattaa catcatctaa gacattttca ccgtaaccat aacgatagct gaccccttgt
     5701 aacttaatat caccatttaa ttgactttca ttatgaattg gccgtgacgc ctcaaattca
     5761 ctagcgacca aatacacttc atttaaccgg ttgttagcga ccttagcgct ttgaagctta
     5821 gtctgcaaat taataatatt ctgtagtgga ttaacaaaat aggctaataa agcattatat
     5881 gtcatgagct ccccaactga taactgatta tgaatgacga gattggcgcc cacccataga
     5941 acaacaactt ctaagactaa ctgtataaac agttttaatg cctgttgcaa agtatccgct
     6001 ttaagatagg ctaaactctt acgtagataa tcaacaaatt ctgaatcaat tttctgataa
     6061 cgttccgtct caccattcag cgccttaaca gtttcaatcc catgaagatc ctcaataatg
     6121 gctgaactca aaatagcatt gctttccatt tccttttgat tcaatcgttc aaaggattta
     6181 ttaaaggcta agatgacaac cgcgtagatt ggcaacgaga gtaacgtaat ccaaaaaagt
     6241 gtcatattct ggattaccaa gattgccccc ataataataa cgatgctgac atctaaaaac
     6301 agcgaaacaa ttgtgctagc taacgcatca ataatcttac tggcatccgt aaaccttgaa
     6361 acaatttccc ccgtccgccg agtggcaaaa aaactcattg gcaattcaaa gacgtgccga
     6421 atatagccta aaataatttc aatcgaaagt cgttgaccta aaaccgccaa taaaaaattc
     6481 tgggcataag taaagatagc ctgaaaggta taaaaaacga ttagaccaat tgccaccact
     6541 gccaatgtac tgtgcatatt attaggaata taagtatcaa tcaccgcttg taagaaataa
     6601 gacccacaga tactaataat cgtgattaaa actgcagcaa gcacaatatt aataaccagt
     6661 cggcgctgct ttaataagct tggaataaat ccccatagtg agcccttatc ttgcttaact
     6721 ggcttatatt ccgacttcgg tgcaaagaaa agggcaactc cggaccattc gctttcaaac
     6781 cgttcctttg acatactgat aaccgcaact gttgggtccg gatcagcaat cacgacatgc
     6841 gttttcgagg tttttacaac aacataaaaa tgctgtagat ccccattttt ggtaacatgc
     6901 acaatgaatg gcaatggtaa atcttggaca tcgaaaagac tcatatctgc ttgaattgct
     6961 ttggtttcaa aacctaactt ttcggccgtt tttactaatc ctaatgccgt agtcccttct
     7021 aaactcgttt tagcaatatt tcttagatag gccaatgatg ttgtcgaacc ataatttttc
     7081 aaaatcattg ctaaagctgc gaccccacag tccatctcgt caacttgcgc aacatagttt
     7141 ctccaatgca tacttgtact cccctcacca attattaagt atcagtatta gtttattatg
     7201 ggctaacaaa tgttatcgta tgccaactat ctattaacgt acataatctt acgatgaatg
     7261 tcctcatcag gcttaacggt taaacatcaa ctagctagca ttggtatttg acgttaagag
     7321 aacgtttttt tacttttata attttttcaa caatctggta aaaaaataaa ttaaactaaa
     7381 tttgtttcaa ataacatcat acaaggggga ttatttatgc tacagtttga gaaattacaa
     7441 tattccaggt tgccgcaaaa aaagcttgcc aaaatatctg gtggttttaa tcggggcggt
     7501 tataactttg gtaaaagtgt tcgacatgtt gttgatgcaa ttggttcagt tgcaggcatt
     7561 cgtggtattt tgaaaagtat tcgttaattt tcttggggga gatcaacaat tatgaaaaaa
     7621 tttctagttt tgcgtgaccg tgaattaaat gctatttcag gtggcgtttt ccatgcctat
     7681 agcgcgcgtg gcgttcggaa caattataaa agtgctgttg ggcctgccga ttgggtcatt
     7741 agcgctgtcc gaggattcat ccacggatag ttcaagccat caagtttaag cactataaga
     7801 aagcactcga tttatgactg ggcctgcagt gctcagcctt tttagtttat atggggggaa
     7861 ttttaactat gccattaata aaagtaataa tcacagccat ttactaccta atagtgctct
     7921 ttttaatgaa tcctttgact gatattatgg gaataaaaga cggacccttt caattcatat
     7981 taactgaatc tattatatta atcgcggtaa tcattctgaa taggcgatat gttaaacaac
     8041 ctatccactg gctacccgtt aatatcatgt caatattaag gaagaatagt ctgcctttga
     8101 gcctagcaat aatatttcta cttattttct ttcgaaacca catgtatcaa tttttaatct
     8161 cattattact ttcgttgatt gtagcgataa ctgaagaata cgcttttcgt ggcatgatat
     8221 tcagaacgct tttagcacta aaccttaaaa aatttgccac attgcaggcc accatcgctt
     8281 cgatgatgac tgcttcgctt atttttgcgg ctatgcattt ggtcaacctt ttatcacagc
     8341 ccgtatggtc agtattgtgt caagttctct atgttattgg gttaggtatt ttacttgcag
     8401 caatctattt aaaaaccgga agcttactag ctgccattag tgtccattgg ttgatagatt
     8461 tttccagttt ttattctcaa ggtattgatc caactcaatc acccattaac gggccaatgg
     8521 aagctcttct aaaggggctc tttctaaata ttttattcat tggcattgct acgtttatcc
     8581 tatcctctaa gcattggaag ttattgagta tcctaaatat tgaagataaa atagacgagt
     8641 aatcatccat tctgaattcc tataaattat tgtttgcagc actacaattt caattatctc
     8701 tgaagttttg gattacgcta agagctagtc atatcgctaa ctaaatttca cgtcttaacg
     8761 ctatgctaat atactttacg atcgagtact gtgcttactt tttagtcatt ttaatactca
     8821 taagatcaca actccaacta tcttcagcac ctatattata taatcagttt tcatattcat
     8881 aacaaaagag ccctgtcaaa taacactgac agaagctcta aataatatta aaaaactagt
     8941 tatctctcaa caacttattc aattcccgcg actttctaaa cgaagcctta cacctaattt
     9001 caccgtcgag caacaactct ttttctttat agtcaaaact tcgcaaatga tttaaattta
     9061 ccaacgagct cttatcgcat cggaaaaatt gcggatactt ttcttcgagc gcatttaaat
     9121 ttcctgggaa ctcagcaacc ttattaatag catggagctg tacgctgccc ggtcgcagtt
     9181 tagatgtact caacaaaatc acatcatcta atgcgagtga aaagtatcgc gttcctaact
     9241 tatagttaaa aacatctttg cgctggctat tagtcttttt taattcgttc tgtactacat
     9301 tgatgtcctt aataatcctt tgcgtaatta ggtcagcaga ctgatctttt aaaatataat
     9361 ccaacggtgc aatccgccgt tccagagtaa caaatgatag ctcatcgtgt gttgtaatga
     9421 aaactatctt ggccaaaggt atcgctgctc gaattcgact agctaattcc agtccagcct
     9481 gtttgtcctc accgatttcc atatctaaaa agaaaagacc atcttgctgt tgattcaagt
     9541 ctgctagaat tattttttgg tcatccgttg ccgctctaag cgccattgca aactcattaa
     9601 tcataattgt attattgatg gtcttacgat aattatctct ttgctcagca ttatcctcgt
     9661 ataaataaat tggaaacaat cattcttcct ccaaaattgt caaagttata ataactcggt
     9721 catttttgct gtcaacatcc aggaaaaaat tcttttgttt gtctaccaat tgttgcacat
     9781 ttgataggcc aaagccacgc tgactcccct tggtggacgc gcctaattcg aacatcttat
     9841 tcacatcaag tttcttatta gttgaatttc tcactgaaat ttctttcgtt tcatgtagcg
     9901 agttaaatgc acaagttacc tgcttatctg gagtagactt ggccgcatca atcgcattat
     9961 ccaataaatt accaacaatt cgaacaacat ctaccaaatt atgctgaatt atgaattcgc
    10021 tctgatcaag ttcgagactc agctcaatcc ctttagtttg ggcatcgaaa aatttctgta
    10081 caattaatcc ccgtaatgtt tcattaccaa cgtgctgaat tttggctatt tttccactat
    10141 ctaacgacgt gtcgatagcg ctctgcgcaa ttaattcttt aaagtatggt agttgttctg
    10201 aagaactccc gctagatatg gaatcttgca atgccaacat aacattcttg taatcatgct
    10261 tgaaccttct taactcaaga tattgttgtt caacactctt caaatattca tttaattgtg
    10321 tattttgttt cgcctgatag ctagcctctt gctttttcat gtacgaccga ataaaaaaaa
    10381 acatctgcca cagcatcata agtaacatta caataaatga agttattaaa gttaattgaa
    10441 tggttgccgt aatattttcg tttaagctta ttaacataat actttcaata gcaacataaa
    10501 atattagaat caactcaaat aacgatttac ttaaatttaa ttcctttatc ttccgattaa
    10561 cactcactat tttatgacag taccgtctat agaaaaataa aatagcataa ttaataataa
    10621 taacaaatat tacatatatt attaacacct catgtgtgta atactgtaca cccatcaggt
    10681 tagagacatt atacaatcct ctaacactca ttcttcctag aaacattgca atattaccga
    10741 tcaaaacttg gataatcaca actagtagca aaattccact cttatcataa ttcaaacttt
    10801 ttttttgaat aaattgacta gcaaaattaa tcaataccat gattagcaga ataaaatctg
    10861 caacaaaaac actcaatact ccccaaaaaa atgttaaaac cagtattttc aaaacacttt
    10921 tccaattaaa taaaccagat aaaaaatagt accataacaa aactactaga acagaggtaa
    10981 atccctggta aaaggtatca acaacgccaa aatccagcat gtggaacacc acctaattta
    11041 tctttttatt aaagatttaa aaaattttgt cagtgttttg cgagaaacat tatttccata
    11101 cattaatgaa acgctctgga acttcccacc acttaccttt tgtagttgct caacatctaa
    11161 acttttacct actactttat caaaagacat actattttta ttcataataa taacccctcc
    11221 ttatctgtaa acttaacatg attatcaata tttttgcaaa atcaagtatt aacgttaaat
    11281 tatatagttt taacgttaat gttcatttat attgtaatac atctaaatca tatccatcaa
    11341 ttaaacacta ttattaaaag taagtaaaac acatacatac tgcgattgta tatatacgga
    11401 taagcaagta ctacaaccat gaaggacaca atccaaaaac cattatgaat gcttaatgtt
    11461 atttacccgt ttttaatcat tgataaaatg attttcctaa tggctccaat cgtcggatac
    11521 tcactttaaa agctacgtta agtcaggtga atagtacgct aataaattta aaaatgcttt
    11581 ttttagaatt gtagcgtatc ttaataaatg tacttaaatt taggaacgca tatcatgtaa
    11641 attaaattaa ctatatttaa gtaaatttga gaaattaact gctgatccta aaaagaatat
    11701 ttctggtggc cgccagagtc gtaagaatgt cgttgaatac gtgtttgaat cggtcggtcg
    11761 cacgcactat aattgatgtc tcgggggatt ataatagatg atagaaattg atttcaaaag
    11821 aagatattac ccgctagtat tagtgctctt tgtggctggt tatatgggtg cgattttcct
    11881 taatatttat tttgattggt tagcaatgct tacagctgga ataattagtt tagtaatgct
    11941 atatggtttt tctaacttaa aactattctt tcaaccattg ccctcaccaa agtggcgtat
    12001 agtgatgaag tatgtgcttt tactgtttgt tctggaagtc actgcgattg tggttatagc
    12061 tattattaat tcgcatgctc tattgtcatt tcacaataca acattgacaa ctagttcaac
    12121 tgggcaagat tatcctttaa ttgaaagagt a
//
