Select genomic region:
Overview
1.1
1.2
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1.4
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1.6
1.7
1.8
1.9
1.10
1.11
1.12

### Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaPNOABPKD_1 (original name was: gnl|Prokka|PNOABPKD_1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1 | CDPS | 132,022 | 152,768 | pulcherriminic acid | Other | 100%
Region 2 | sactipeptide | 378,376 | 399,987 | subtilosin A | RiPP:Thiopeptide | 100%
Region 3 | other | 406,767 | 448,185 | bacilysin | Other | 100%
Region 4 | epipeptide | 659,445 | 681,143 | thailanstatin A | NRP+Polyketide | 10%
Region 5 | NRPS | 1,104,159 | 1,169,550 | surfactin | NRP:Lipopeptide | 82%
Region 6 | terpene | 1,908,843 | 1,929,646 |
Region 7 | transAT-PKS,PKS-like,T3PKS,NRPS | 2,521,361 | 2,636,113 | bacillaene | Polyketide+NRP | 100%
Region 8 | NRPS,betalactone | 2,711,427 | 2,789,190 | fengycin | NRP | 100%
Region 9 | terpene | 2,846,035 | 2,867,933 |
Region 10 | lanthipeptide-class-ii | 2,889,491 | 2,912,376 | bacillomycin D | Polyketide+NRP:Lipopeptide | 20%
Region 11 | T3PKS | 3,053,847 | 3,094,944 | 1-carbapen-2-em-3-carboxylic acid | Other | 16%
Region 12 | NRP-metallophore,NRPS | 4,036,045 | 4,087,822 | bacillibactin | NRP | 100%

gnlProkkaPNOABPKD_1 - Region 1 - CDPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 132,022 - 152,768 nt. (total: 20,747 nt) Show pHMM detection rules used
CDPS: (CDPS or cycdipepsynth)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
NRPS/PKS substrates
NRPS/PKS substrate predictions
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

gnlProkkaPNOABPKD_1 - Region 2 - sactipeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 378,376 - 399,987 nt. (total: 21,612 nt) Show pHMM detection rules used
sactipeptide: (subtilosin or thuricin or TIGR04404 or Subtilosin_A or skfc)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Sactipeptides
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Sactipeptide predictions
Lists the possible core peptides for each biosynthetic enzyme. Each core peptide shows the leader and core peptide sequences.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.

#### Sactipeptide(s) for ctg1_375

ctg1_375
Leader:
MKKAVIVENK
Core:
GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

#### antiSMASH-DB 4.0 matches for ctg1_375

100.0% NC_000964.3 and 235 others:
NC_014479.1 Sactipeptides: BSUW23_RS18740_sactipeptide NC_014639.1 Sactipeptides: BATR1942_RS15950_sactipeptide NC_014976.1 Sactipeptides: BSN5_RS09700_sactipeptide NC_016047.1 Sactipeptides: GYO_RS41165_sactipeptide NC_017195.1 Sactipeptides: I33_RS18040_sactipeptide NC_017743.1 Sactipeptides: MY9_RS18920_sactipeptide NC_019896.1 Sactipeptides: A7A1_RS01935_sactipeptide NC_020244.1 Sactipeptides: C663_RS18295_sactipeptide NZ_BDDH01000003.1 Sactipeptides: A7P71_RS10610_sactipeptide NZ_CABIVP010000002.1 Sactipeptides: FY199_RS09010_sactipeptide NZ_CP007409.1 Sactipeptides: Q433_RS18950_sactipeptide NZ_CP009796.1 Sactipeptides: OB04_RS19085_sactipeptide NZ_CP011101.1 Sactipeptides: bslm_RS18365_sactipeptide NZ_CP011534.1 Sactipeptides: ABA10_RS18725_sactipeptide NZ_CP011802.1 Sactipeptides: D068_RS17505_sactipeptide NZ_CP016767.1 Sactipeptides: BCV50_RS14935_sactipeptide NZ_CP017072.1 Sactipeptides: BGM23_RS02945_sactipeptide NZ_CP017112.1 Sactipeptides: BS16045_RS19810_sactipeptide NZ_CP017313.1 Sactipeptides: BH660_RS14630_sactipeptide NZ_CP017314.1 Sactipeptides: BSBS38_RS19215_sactipeptide NZ_CP017676.1 Sactipeptides: BKN48_RS08085_sactipeptide NZ_CP018173.1 Sactipeptides: BAX60_RS03615_sactipeptide NZ_CP020367.1 Sactipeptides: BSK2_RS19060_sactipeptide NZ_CP020722.1 Sactipeptides: B7470_RS09560_sactipeptide NZ_CP020915.1 Sactipeptides: B9L64_RS11255_sactipeptide NZ_CP021169.1 Sactipeptides: B9N48_RS18685_sactipeptide NZ_CP021498.1 Sactipeptides: S101444_RS19170_sactipeptide NZ_CP021892.1 Sactipeptides: S100333_RS19720_sactipeptide NZ_CP021903.1 Sactipeptides: CD007_RS18975_sactipeptide NZ_CP021911.1 Sactipeptides: CDO84_RS18225_sactipeptide NZ_CP021921.1 Sactipeptides: S101392_RS19440_sactipeptide NZ_CP022391.1 Sactipeptides: CFK25_RS18875_sactipeptide NZ_CP022890.1 Sactipeptides: CJZ70_RS01210_sactipeptide NZ_CP023257.1 Sactipeptides: CLD04_RS19470_sactipeptide NZ_CP023409.1 Sactipeptides: Bateq7PJ16_RS20450_sactipeptide NZ_CP025941.1 Sactipeptides: C0W65_RS07300_sactipeptide NZ_CP026010.1 Sactipeptides: BS11774_RS03710_sactipeptide NZ_CP026030.1 Sactipeptides: C2H91_RS12110_sactipeptide NZ_CP026035.1 Sactipeptides: C2H96_RS13375_sactipeptide NZ_CP026036.1 Sactipeptides: C2H93_RS16885_sactipeptide NZ_CP026521.1 Sactipeptides: C1T29_RS22385_sactipeptide NZ_CP028201.1 Sactipeptides: C7M16_RS17535_sactipeptide NZ_CP028202.1 Sactipeptides: C7M17_RS17600_sactipeptide NZ_CP028217.1 Sactipeptides: C7M29_RS06900_sactipeptide NZ_CP028218.1 Sactipeptides: C7M30_RS12605_sactipeptide NZ_CP028812.1 Sactipeptides: DAE22_RS20770_sactipeptide NZ_CP029364.1 Sactipeptides: DIC78_RS12275_sactipeptide NZ_CP029461.1 Sactipeptides: DJ572_RS18795_sactipeptide NZ_CP029465.1 Sactipeptides: DKG76_RS19825_sactipeptide NZ_CP029609.1 Sactipeptides: DL538_RS20030_sactipeptide NZ_CP031675.1 Sactipeptides: DYS67_RS19275_sactipeptide NZ_CP031783.1 Sactipeptides: D0808_RS00710_sactipeptide NZ_CP031784.1 Sactipeptides: D0819_RS14700_sactipeptide NZ_CP032853.1 Sactipeptides: D9C10_RS17955_sactipeptide NZ_CP032855.1 Sactipeptides: D9C11_RS09165_sactipeptide NZ_CP035161.1 Sactipeptides: EQH88_RS19675_sactipeptide NZ_CP035167.1 Sactipeptides: EQJ08_RS19095_sactipeptide NZ_CP035226.1 Sactipeptides: EQW70_RS20085_sactipeptide NZ_CP035231.1 Sactipeptides: EQZ01_RS19685_sactipeptide NZ_CP035391.1 Sactipeptides: ES965_RS19370_sactipeptide NZ_CP035395.1 Sactipeptides: ES968_RS19740_sactipeptide NZ_CP035401.1 Sactipeptides: ETA19_RS19595_sactipeptide NZ_CP035402.1 Sactipeptides: ES969_RS19660_sactipeptide NZ_CP035403.1 Sactipeptides: ETA15_RS19805_sactipeptide NZ_CP035406.1 Sactipeptides: ETK61_RS20735_sactipeptide NZ_CP035413.1 Sactipeptides: ETL58_RS19505_sactipeptide NZ_CP039935.1 Sactipeptides: FCJ76_RS19255_sactipeptide NZ_CP045006.1 Sactipeptides: F9B13_RS01950_sactipeptide NZ_CP045425.1 Sactipeptides: GCU76_RS20710_sactipeptide NZ_CP045816.1 Sactipeptides: GII86_RS19920_sactipeptide NZ_CP045824.1 Sactipeptides: GII78_RS20125_sactipeptide NZ_CP046591.1 Sactipeptides: GO004_RS15965_sactipeptide NZ_CP046860.1 Sactipeptides: GPJ55_RS11605_sactipeptide NZ_CP047645.1 Sactipeptides: GSN02_RS19265_sactipeptide NZ_CP049924.1 Sactipeptides: G4G26_RS18960_sactipeptide NZ_CP050705.1 Sactipeptides: HCU65_RS18920_sactipeptide NZ_CP051462.1 Sactipeptides: HC662_RS19240_sactipeptide NZ_CP051464.1 Sactipeptides: HC660_RS18970_sactipeptide NZ_CP054050.1 Sactipeptides: HNV25_RS02005_sactipeptide NZ_CP054177.1 Sactipeptides: HR084_RS18935_sactipeptide NZ_CP054584.1 Sactipeptides: HT135_RS19775_sactipeptide NZ_CP060193.1 Sactipeptides: H7F27_RS02180_sactipeptide NZ_CP060417.1 Sactipeptides: H8S71_RS18495_sactipeptide NZ_CP061284.1 Sactipeptides: ICJ61_RS19715_sactipeptide NZ_CP061870.1 Sactipeptides: IE382_RS22305_sactipeptide NZ_CP062497.1 Sactipeptides: IHV08_RS19770_sactipeptide NZ_CP063276.1 Sactipeptides: IM743_RS18070_sactipeptide NZ_CP065858.1 Sactipeptides: I7X10_RS03370_sactipeptide NZ_CP069789.1 Sactipeptides: JR441_RS19085_sactipeptide NZ_CP070483.1 Sactipeptides: JQX68_RS19175_sactipeptide NZ_CP070976.1 Sactipeptides: JYG31_RS19675_sactipeptide NZ_CP071043.1 Sactipeptides: JS609_RS19245_sactipeptide NZ_CP073265.1 Sactipeptides: KCX77_RS18900_sactipeptide NZ_CP075344.1 Sactipeptides: KIL00_RS20100_sactipeptide NZ_CP076083.1 Sactipeptides: KFF76_RS18635_sactipeptide NZ_CP079759.1 Sactipeptides: KXZ66_RS19695_sactipeptide NZ_CP080508.1 Sactipeptides: K0V03_RS08595_sactipeptide NZ_CP089148.1 Sactipeptides: LRO88_RS20980_sactipeptide NZ_CP090125.1 Sactipeptides: LXE94_RS19505_sactipeptide NZ_CP093289.1 Sactipeptides: MNG38_RS19730_sactipeptide NZ_CP093546.1 Sactipeptides: MOW04_RS19180_sactipeptide NZ_CP095736.1 Sactipeptides: MX663_RS20090_sactipeptide NZ_CP096590.1 Sactipeptides: M0696_RS18995_sactipeptide NZ_CP096889.1 Sactipeptides: EFK13_RS19225_sactipeptide NZ_CP098738.1 Sactipeptides: NDR85_RS18965_sactipeptide NZ_CP100651.1 Sactipeptides: NLW79_RS19990_sactipeptide NZ_CP100752.1 Sactipeptides: NLV76_RS19060_sactipeptide NZ_CP101718.1 Sactipeptides: NPA28_RS19075_sactipeptide NZ_CP101936.1 Sactipeptides: NP434_RS18980_sactipeptide NZ_CP103352.1 Sactipeptides: NX823_RS19780_sactipeptide NZ_CP104878.1 Sactipeptides: N8A75_RS20105_sactipeptide NZ_CP107539.1 Sactipeptides: OEG95_RS19105_sactipeptide NZ_CP110264.1 Sactipeptides: OMK57_RS18975_sactipeptide NZ_CP114899.1 Sactipeptides: O6U12_RS19480_sactipeptide NZ_CP116773.1 Sactipeptides: PNF29_RS01990_sactipeptide NZ_FTMW01000001.1 Sactipeptides: BW968_RS02045_sactipeptide NZ_JAAUXF010000005.1 Sactipeptides: HC742_RS19325_sactipeptide NZ_JABRUZ010000003.1 Sactipeptides: HRF55_RS03085_sactipeptide NZ_JABRVH010000018.1 Sactipeptides: HRF53_RS09100_sactipeptide NZ_JABUKD010000002.1 Sactipeptides: HRW04_RS09345_sactipeptide NZ_JAEACL010000001.1 Sactipeptides: I5F14_RS00800_sactipeptide NZ_JAHVOC010000002.1 Sactipeptides: KXD37_RS07830_sactipeptide NZ_JAJFDG010000003.1 Sactipeptides: LJF29_RS11575_sactipeptide NZ_JAJHUI010000011.1 Sactipeptides: LK399_RS16325_sactipeptide NZ_JALAJC010000012.1 Sactipeptides: MOB18_RS16080_sactipeptide NZ_JALAKW010000005.1 Sactipeptides: MOB93_RS12665_sactipeptide NZ_JALAKZ010000001.1 Sactipeptides: MOB76_RS02240_sactipeptide NZ_JALALA010000011.1 Sactipeptides: MOB82_RS15020_sactipeptide NZ_JALALE010000020.1 Sactipeptides: MOB33_RS20855_sactipeptide NZ_JALALO010000006.1 Sactipeptides: MOB75_RS09230_sactipeptide NZ_JALAMD010000002.1 Sactipeptides: MOB22_RS02315_sactipeptide NZ_JALAME010000005.1 Sactipeptides: MOC02_RS13805_sactipeptide NZ_JALAMJ010000012.1 Sactipeptides: MOB80_RS16635_sactipeptide NZ_JALAMO010000007.1 Sactipeptides: MOB98_RS08535_sactipeptide NZ_JALAMR010000019.1 Sactipeptides: MOC09_RS17975_sactipeptide NZ_JALAMZ010000002.1 Sactipeptides: MOC43_RS01370_sactipeptide NZ_JALANN010000012.1 Sactipeptides: MOC49_RS18290_sactipeptide NZ_JALANX010000001.1 Sactipeptides: MOC25_RS03365_sactipeptide NZ_JALAPT010000001.1 Sactipeptides: MOC95_RS01580_sactipeptide NZ_JALAPV010000005.1 Sactipeptides: MOC91_RS13515_sactipeptide NZ_JALAPW010000003.1 Sactipeptides: MOD18_RS06235_sactipeptide NZ_JALAPX010000003.1 Sactipeptides: MOC97_RS06805_sactipeptide NZ_JALAPZ010000002.1 Sactipeptides: MOC81_RS03830_sactipeptide NZ_JALAQA010000008.1 Sactipeptides: MOD07_RS14955_sactipeptide NZ_JALAQC010000001.1 Sactipeptides: MOD00_RS01290_sactipeptide NZ_JALAQD010000002.1 Sactipeptides: MOD08_RS05770_sactipeptide NZ_JALAQE010000002.1 Sactipeptides: MOD19_RS04725_sactipeptide NZ_JALASB010000002.1 Sactipeptides: MOD42_RS03685_sactipeptide NZ_JALASC010000024.1 Sactipeptides: MOD69_RS20580_sactipeptide NZ_JALASM010000006.1 Sactipeptides: MOD51_RS10970_sactipeptide NZ_JALASR010000006.1 Sactipeptides: MOD87_RS10780_sactipeptide NZ_JALAST010000011.1 Sactipeptides: MOE17_RS14670_sactipeptide NZ_JALASW010000005.1 Sactipeptides: MOE15_RS06925_sactipeptide NZ_JALATC010000001.1 Sactipeptides: MOD56_RS03380_sactipeptide NZ_JALATD010000001.1 Sactipeptides: MOE02_RS03350_sactipeptide NZ_JALATE010000006.1 Sactipeptides: MOD98_RS11440_sactipeptide NZ_JALATF010000003.1 Sactipeptides: MOD44_RS09960_sactipeptide NZ_JALATG010000002.1 Sactipeptides: MOE16_RS03490_sactipeptide NZ_JALATJ010000007.1 Sactipeptides: MOD90_RS15770_sactipeptide NZ_JALATU010000001.1 Sactipeptides: MOE27_RS01985_sactipeptide NZ_JALATV010000005.1 Sactipeptides: MOD97_RS07020_sactipeptide NZ_JALAUA010000008.1 Sactipeptides: MOD32_RS16030_sactipeptide NZ_JALAUD010000001.1 Sactipeptides: MOE28_RS03345_sactipeptide NZ_JALAUJ010000006.1 Sactipeptides: MOE37_RS12685_sactipeptide NZ_JALAUK010000012.1 Sactipeptides: MOE38_RS11825_sactipeptide NZ_JALAUV010000003.1 Sactipeptides: MOE71_RS06545_sactipeptide NZ_JALAUW010000015.1 Sactipeptides: MOE83_RS13210_sactipeptide NZ_JALAVA010000002.1 Sactipeptides: MOE81_RS02625_sactipeptide NZ_JALAVE010000001.1 Sactipeptides: MOE67_RS03645_sactipeptide NZ_JALAVI010000011.1 Sactipeptides: MOE80_RS14660_sactipeptide NZ_JALAVK010000006.1 Sactipeptides: MOE96_RS10120_sactipeptide NZ_JALAVL010000002.1 Sactipeptides: MOE60_RS03290_sactipeptide NZ_JALAVM010000009.1 Sactipeptides: MOE49_RS16195_sactipeptide NZ_JALAVO010000008.1 Sactipeptides: MOE63_RS14665_sactipeptide NZ_JALAVQ010000003.1 Sactipeptides: MOE59_RS02420_sactipeptide NZ_JALAVS010000002.1 Sactipeptides: MOE46_RS02250_sactipeptide NZ_JALAVT010000005.1 Sactipeptides: MOF25_RS08325_sactipeptide NZ_JALAVU010000004.1 Sactipeptides: MOE78_RS09660_sactipeptide NZ_JALAVV010000004.1 Sactipeptides: MOE66_RS02855_sactipeptide NZ_JALAVW010000001.1 Sactipeptides: MOE86_RS01005_sactipeptide NZ_JALAVX010000009.1 Sactipeptides: MOE40_RS07525_sactipeptide NZ_JALAVZ010000002.1 Sactipeptides: MOF00_RS02525_sactipeptide NZ_JALAWB010000008.1 Sactipeptides: MOE87_RS15020_sactipeptide NZ_JALAWK010000002.1 Sactipeptides: MOF06_RS12140_sactipeptide NZ_JALAWW010000010.1 Sactipeptides: MOF23_RS17300_sactipeptide NZ_JALAXQ010000012.1 Sactipeptides: MOF24_RS14120_sactipeptide NZ_JALAXV010000001.1 Sactipeptides: MOF15_RS00375_sactipeptide NZ_JALAYA010000016.1 Sactipeptides: MOF34_RS08915_sactipeptide NZ_JALAYD010000019.1 Sactipeptides: MOF39_RS20725_sactipeptide NZ_JALNTO010000006.1 Sactipeptides: MTN95_RS11045_sactipeptide NZ_JAMDFN010000008.1 Sactipeptides: M3M31_RS18245_sactipeptide NZ_JAMYDW010000003.1 Sactipeptides: NHM07_RS10830_sactipeptide NZ_JANBMP010000002.1 Sactipeptides: NL430_RS07940_sactipeptide NZ_JANDGG010000001.1 Sactipeptides: NKU38_RS03365_sactipeptide NZ_JANFAP010000001.1 Sactipeptides: NEC81_RS02065_sactipeptide NZ_JAQFFE010000015.1 Sactipeptides: PG051_RS13540_sactipeptide NZ_JAQOXM010000001.1 Sactipeptides: PO770_RS01950_sactipeptide NZ_JH600279.1 Sactipeptides: GYU_RS0104160_sactipeptide NZ_JXHL01000020.1 Sactipeptides: B4069_RS07025_sactipeptide NZ_JXHP01000031.1 Sactipeptides: B4073_RS09425_sactipeptide NZ_JXHR01000010.1 Sactipeptides: B4146_RS06925_sactipeptide NZ_KZ848487.1 Sactipeptides: DSL71_RS14015_sactipeptide NZ_LPVE01000021.1 Sactipeptides: AU385_RS06600_sactipeptide NZ_LSBB01000001.1 Sactipeptides: AXI57_RS01770_sactipeptide NZ_LUUT01000004.1 Sactipeptides: A6751_RS18460_sactipeptide NZ_MOEO01000004.1 Sactipeptides: BLL41_RS09830_sactipeptide NZ_MUXL01000002.1 Sactipeptides: B0W20_RS08845_sactipeptide NZ_MZZI01000001.1 Sactipeptides: B2G85_RS18515_sactipeptide NZ_NBBO01000003.1 Sactipeptides: B6K89_RS01830_sactipeptide NZ_NERK01000024.1 Sactipeptides: B9T64_RS18540_sactipeptide NZ_NJRD01000003.1 Sactipeptides: CE053_RS09115_sactipeptide NZ_NJRE01000002.1 Sactipeptides: CE047_RS07205_sactipeptide NZ_NKAK01000003.1 Sactipeptides: CE489_RS10400_sactipeptide NZ_NMOM01000004.1 Sactipeptides: CFI07_RS07245_sactipeptide NZ_PHIE01000002.1 Sactipeptides: CVV77_RS10760_sactipeptide NZ_PJCT01000002.1 Sactipeptides: CW370_RS11825_sactipeptide NZ_PVQM01000002.1 Sactipeptides: C6W22_RS11490_sactipeptide NZ_PVQN01000002.1 Sactipeptides: C6W23_RS05885_sactipeptide NZ_PVRK01000001.1 Sactipeptides: C6350_RS02025_sactipeptide NZ_PVWC01000004.1 Sactipeptides: C6372_RS11675_sactipeptide NZ_QRFZ01000012.1 Sactipeptides: DXT72_RS19010_sactipeptide NZ_SDKE01000003.1 Sactipeptides: EUA35_RS12130_sactipeptide NZ_SHOB01000002.1 Sactipeptides: ES060_RS14270_sactipeptide NZ_SIRN01000006.1 Sactipeptides: EYH65_RS15720_sactipeptide NZ_SNWK01000001.1 Sactipeptides: DFO69_RS02055_sactipeptide NZ_SOBO01000012.1 Sactipeptides: DFO78_RS18210_sactipeptide NZ_SORJ01000001.1 Sactipeptides: BJ795_RS03350_sactipeptide NZ_VBRP01000025.1 Sactipeptides: FE220_RS07065_sactipeptide NZ_VFNF01000001.1 Sactipeptides: FB592_RS03405_sactipeptide NZ_VIOH01000001.1 Sactipeptides: FLN47_RS01935_sactipeptide NZ_VLJK01000012.1 Sactipeptides: L605_RS10195_sactipeptide NZ_VLJL01000006.1 Sactipeptides: L604_RS05585_sactipeptide NZ_VLJX01000001.1 Sactipeptides: L609_RS01950_sactipeptide NZ_VTEK01000003.1 Sactipeptides: FZC71_RS10310_sactipeptide NZ_WTKJ01000004.1 Sactipeptides: NWT17_RS06185_sactipeptide
Sactipeptides: BSU_37350_sactipeptide
1
GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG
33
GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG
1
GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG
33
97.0% NZ_CP092751.1: Sactipeptides: MKF32_RS18515_sactipeptide
1
GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG
33
GCATCSIGA CLVDGPIPDFEIAGATGLFGLWG
1
GCATCSIGAVCLVDGPIPDFEIAGATGLFGLWG
33
93.9% NZ_CP048852.1: Sactipeptides: G4P54_RS19300_sactipeptide
1
GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG
33
GCATCSIGA CLVDGPIPDFE+AGATGLFGLWG
1
GCATCSIGAVCLVDGPIPDFEVAGATGLFGLWG
33
with 15 more sequence matches
90.9% NZ_JALAKO010000018.1 and 1 other:
NZ_JALAOG010000035.1 Sactipeptides: MOC96_RS18415_sactipeptide
Sactipeptides: MOB26_RS11095_sactipeptide
1
GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG
33
GCATCSIGA CLVDGPIPDFEI G TGLFGLWG
1
GCATCSIGAVCLVDGPIPDFEIGGVTGLFGLWG
33
87.9% NZ_CP026362.1 and 3 others:
NZ_CP033052.1 Sactipeptides: D9779_RS19215_sactipeptide NZ_JALAPG010000031.1 Sactipeptides: MOC70_RS13155_sactipeptide NZ_JALAQI010000016.1 Sactipeptides: MOD13_RS11485_sactipeptide
Sactipeptides: BV11031_RS20865_sactipeptide
1
GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG
33
GCATCSIGA CLVDG IPDFEI G TGLFGLWG
1
GCATCSIGAVCLVDGFIPDFEIGGVTGLFGLWG
33
78.8% NZ_NXEM01000021.1: Sactipeptides: CPT06_RS05595_sactipeptide
1
GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG
33
GC TCSIGA CLV+GPIPDF+ G TGLFGLWG
1
GCTTCSIGAVCLVNGPIPDFKTGGVTGLFGLWG
33
72.7% NC_014925.1 and 17 others:
NZ_ANOI01000001.1 Sactipeptides: F779_RS13290_sactipeptide NZ_CP031604.1 Sactipeptides: DNJ55_RS07055_sactipeptide NZ_CP031605.1 Sactipeptides: DRC71_RS00165_sactipeptide NZ_CP035741.1 Sactipeptides: EW136_RS01865_sactipeptide NZ_CP039747.1 Sactipeptides: EFT29_RS00935_sactipeptide NZ_CP054206.2 Sactipeptides: HP560_RS11995_sactipeptide NZ_CP060700.1 Sactipeptides: H9Q12_RS10940_sactipeptide NZ_CP065920.1 Sactipeptides: JC281_RS11580_sactipeptide NZ_CP076465.1 Sactipeptides: KDE16_RS00560_sactipeptide NZ_JANPRJ010000013.1 Sactipeptides: NVR03_RS10250_sactipeptide NZ_JANPRN010000039.1 Sactipeptides: NVR04_RS07875_sactipeptide NZ_JTKO01000012.1 Sactipeptides: NO87_RS10650_sactipeptide NZ_LR134267.1 Sactipeptides: EL085_RS11430_sactipeptide NZ_MQMO01000006.1 Sactipeptides: BSR38_RS07375_sactipeptide NZ_MQNF01000024.1 Sactipeptides: BSR36_RS12515_sactipeptide NZ_QQPJ01000025.1 Sactipeptides: DV949_RS11300_sactipeptide NZ_SEZW01000001.1 Sactipeptides: EWV33_RS08610_sactipeptide
Sactipeptides: SPSINT_RS00615_sactipeptide
1
GCATCSIGAACLVDGPIPDFEIAGATGLFGL
31
GC+TCSIGAACL+DGP+PDFE+ G TG+FGL
1
GCSTCSIGAACLIDGPLPDFEVMGITGIFGL
31
69.7% NZ_CP027770.1: Sactipeptides: C7J90_RS04260_sactipeptide
1
GCATCSIGAACLVDGPIPDFEIAGATGLFGL
31
GC+ CSIGAACL+DGP PDFE+ G TG FGL
1
GCSACSIGAACLIDGPFPDFEVMGITGTFGL
31
69.7% NZ_CP066885.1: Sactipeptides: JGZ27_RS11325_sactipeptide
1
GCATCSIGAACLVDGPIPDFEIAGATGLFGL
31
GC+TCSIG ACL+DGP+PDFE+ G TG+FGL
1
GCSTCSIGVACLIDGPLPDFEVMGITGIFGL
31
69.7% NZ_CP094808.1 and 3 others:
NZ_CP094809.1 Sactipeptides: MUA95_RS01320_sactipeptide NZ_CP094813.1 Sactipeptides: MUA84_RS01300_sactipeptide NZ_VKCY01000004.1 Sactipeptides: FNK43_RS05155_sactipeptide
Sactipeptides: MUA11_RS01375_sactipeptide
1
GCATCSIGAACLVDGPIPDFEIAGATGLFGL
31
GC+ C+IGAACL DGPIPDFE+AG TG FG+
1
GCSACAIGAACLADGPIPDFEVAGITGTFGI
31
66.7% NZ_ATDF02000020.1 and 1 other:
NZ_KV827785.1 Sactipeptides: HMPREF2580_RS10900_sactipeptide
Sactipeptides: M462_RS08950_sactipeptide
1
GCATCSIGAACLVDGPIPDFEIAGATGLFGL
31
GC+ C++GAACL DGPIPDFE+AG TG FG+
1
GCSACAVGAACLADGPIPDFEVAGITGTFGM
31
63.6% NC_022584.1 and 2 others:
NZ_CP047883.1 Sactipeptides: M594_RS05585_sactipeptide NZ_KV802690.1 Sactipeptides: HMPREF2764_RS03300_sactipeptide
Sactipeptides: N596_RS03165_sactipeptide
1
GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG
33
GC+ C+IGA CL DGPIPDFEIAG + +F +G
1
GCSVCAIGAVCLADGPIPDFEIAGVSAVFTAFG
33
63.6% NZ_CP063367.1 and 1 other:
NZ_LR134263.1 Sactipeptides: EL101_RS12790_sactipeptide
Sactipeptides: IPU22_RS12430_sactipeptide
1
GCATCSIGAACLVDGPIPDFEIAGATGLFGL
31
GC+ C++GA CL DGPIPDFE+AG TG FG+
1
GCSACAVGAVCLADGPIPDFEVAGITGTFGI
31
60.6% NZ_LGRV01000006.1: Sactipeptides: AEA09_RS16245_sactipeptide
1
GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG
33
GC+ CSIGA CL+ GP+PDFE+A +G+F +WG
1
GCSACSIGAICLITGPVPDFEVASISGIFSVWG
33
54.5% NZ_CP066713.1: Sactipeptides: JGZ50_RS11620_sactipeptide
2
CATCSIGAACLVDGPIPDFEIAGATGLF
29
C+TCSIGAACL+DGP+PDF G F
1
CSTCSIGAACLIDGPLPDFRSHGNYWNF
28
42.4% NZ_PIZD01000012.1: Sactipeptides: allorf_25390_25524_sactipeptide
2
CATCSIGAACLVDGPIPDFEIAGATGLFGLW
32
C+ C++GA CL DGP PD E+ G + G +
3
CSFCAVGAGCLADGPFPDAEVVGVALIAGAF
33
18.2% NZ_CP016898.1: Lassopeptides: BEN76_RS17395_lassopeptide
14
DGPIPDFEIAGATGLF
29
GP+P++ + G G F
3
KGPLPEYFLMGGGGNF
18
17.1% NC_017030.1: Lanthipeptides: allorf_07530736_07530897_lanthipeptide
1
GCATCSIGAACLVDGPI
17
G +I C VDGP+
11
GVLRPAIARPCFVDGPV
27
Sactipeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists its RODEO score and predicted core sequence.

ctg1_375
  Putative sactipeptide
  RODEO score: 33.0
  Core sequence, approximate: GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG

gnlProkkaPNOABPKD_1 - Region 3 - other
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 406,767 - 448,185 nt. (total: 41,419 nt) Show pHMM detection rules used
other: (LmbU or Neocarzinostat or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin or orf2_PTase)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
gnlProkkaPNOABPKD_1 - Region 4 - epipeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 659,445 - 681,143 nt. (total: 21,699 nt) Show pHMM detection rules used
epipeptide: (TIGR04078 and yydH)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
gnlProkkaPNOABPKD_1 - Region 5 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,104,159 - 1,169,550 nt. (total: 65,392 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
KnownClusterBlast
NRPS/PKS modules
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate cluster in NRPS and PKS regions.
Genes are shown in predicted order, and are only present when containing at least one complete module.
A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
NRPS/PKS products
NRPS/PKS substrates
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 5, location 1104158 - 1169550:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (Glu - Leu - D-Leu) + (Val - Asp - D-Leu) + (Leu)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS substrate predictions
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_1103: Glu - Leu - Leu
  Search NORINE for peptide: strict or relaxed
  AMP-binding (466..867): Glu
  nrpys: Glu
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
    Large clusters prediction:
      Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
    Small clusters prediction:
      glu,gln (Glu, Gln)
    Single AA prediction:
      gln (Gln)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAKDLGVVDK
    Nearest Stachelhaus code(s):
      Glu DAKDLGVVDK (100% 8Å match)
    Stachelhaus code match:
      100% (strong)
  AMP-binding (1510..1908): Leu
  nrpys: Leu
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
    Small clusters prediction:
      Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
    Single AA prediction:
      leu (Leu)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAFMMGMVFK
    Nearest Stachelhaus code(s):
      Leu DAFMMGMVFK (100% 8Å match)
    Stachelhaus code match:
      100% (strong)
  AMP-binding (2550..2938): Leu
  nrpys: Leu
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
    Small clusters prediction:
      Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
    Single AA prediction:
      leu (Leu)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAWFLGNVVK
    Nearest Stachelhaus code(s):
      Leu DAWFLGNVVK (97% 8Å match)
    Stachelhaus code match:
      100% (strong)
ctg1_1104: Val - Asp - Leu
  Search NORINE for peptide: strict or relaxed
  AMP-binding (470..864): Val
  nrpys: Val
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
    Small clusters prediction:
      Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
    Single AA prediction:
      val (Val)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAFWIGGTFK
    Nearest Stachelhaus code(s):
      Val DAFWIGGTFK (100% 8Å match)
    Stachelhaus code match:
      100% (strong)
  AMP-binding (1501..1904): Asp
  nrpys: Asp
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
    Large clusters prediction:
      Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
    Small clusters prediction:
      asp,asn (Asp, Asn)
    Single AA prediction:
      asp (Asp)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DLTKVGHIGK
    Nearest Stachelhaus code(s):
      Asp DLTKVGHIGK (100% 8Å match)
    Stachelhaus code match:
      100% (strong)
  AMP-binding (2546..2934): Leu
  nrpys: Leu
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
    Small clusters prediction:
      Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
    Single AA prediction:
      leu (Leu)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAWFLGNVVK
    Nearest Stachelhaus code(s):
      Leu DAWFLGNVVK (97% 8Å match)
    Stachelhaus code match:
      100% (strong)
ctg1_1105: Leu
  Search NORINE for peptide: strict or relaxed
  AMP-binding (469..867): Leu
  nrpys: Leu
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
    Small clusters prediction:
      Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
    Single AA prediction:
      leu (Leu)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAFFLGCVFK
    Nearest Stachelhaus code(s):
      Leu DAFFLGCVFK (100% 8Å match)
    Stachelhaus code match:
      100% (strong)

gnlProkkaPNOABPKD_1 - Region 6 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,908,843 - 1,929,646 nt. (total: 20,804 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

gnlProkkaPNOABPKD_1 - Region 7 - NRPS,PKS-like,T3PKS,transAT-PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,521,361 - 2,636,113 nt. (total: 114,753 nt) Show pHMM detection rules used
transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))
PKS-like: (t2pks2 or ksIII)
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
KnownClusterBlast
NRPS/PKS modules
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate cluster in NRPS and PKS regions.
Genes are shown in predicted order, and are only present when containing at least one complete module.
A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
NRPS/PKS products
NRPS/PKS substrates
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 7, location 2521360 - 2636113:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (Gly - ccmal - ohmal - mal) + (ccmal - mal - ohmal - mal) + (Me-ccmal - ohmal - mal) + (Ala - ccmal - ccmal - Me-ccmal) + (mal - mal)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS substrate predictions
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_2524: mal
  PKS_AT (4..284): mal
  ATSignature: Malonyl-CoA
  Top 3 matches:
    Malonyl-CoA: 87.5%
    inactive: 62.5%
  minowa: Malonyl-CoA
  Prediction, score:
    Malonyl-CoA: 98.2
    Methoxymalonyl-CoA: 54.0
    inactive: 36.8
    Methylmalonyl-CoA: 35.6
    Propionyl-CoA: 22.9
    Ethylmalonyl-CoA: 10.8
    2-Methylbutyryl-CoA: 9.4
    Isobutyryl-CoA: 9.1
    trans-1,2-CPDA: 0.0
    fatty_acid: 0.0
    CHC-CoA: 0.0
    Benzoyl-CoA: 0.0
    Acetyl-CoA: 0.0
    3-Methylbutyryl-CoA: 0.0
ctg1_2526: pk
  PKS_AT (7..293): pk
  ATSignature: (unknown)
  No matches above 50%
  minowa: inactive
  Prediction, score:
    inactive: 30.1
    Malonyl-CoA: 24.5
    Benzoyl-CoA: 8.7
    Isobutyryl-CoA: 8.6
    trans-1,2-CPDA: 0.0
    fatty_acid: 0.0
    Propionyl-CoA: 0.0
    Methylmalonyl-CoA: 0.0
    Methoxymalonyl-CoA: 0.0
    Ethylmalonyl-CoA: 0.0
    CHC-CoA: 0.0
    Acetyl-CoA: 0.0
    3-Methylbutyryl-CoA: 0.0
    2-Methylbutyryl-CoA: 0.0
ctg1_2527: mal
  PKS_AT (4..288): mal
  ATSignature: Malonyl-CoA
  Top 3 matches:
    Malonyl-CoA: 87.5%
    inactive: 66.7%
  minowa: Malonyl-CoA
  Prediction, score:
    Malonyl-CoA: 95.0
    inactive: 41.2
    Methoxymalonyl-CoA: 29.1
    Methylmalonyl-CoA: 22.1
    Propionyl-CoA: 16.3
    trans-1,2-CPDA: 0.0
    fatty_acid: 0.0
    Isobutyryl-CoA: 0.0
    Ethylmalonyl-CoA: 0.0
    CHC-CoA: 0.0
    Benzoyl-CoA: 0.0
    Acetyl-CoA: 0.0
    3-Methylbutyryl-CoA: 0.0
    2-Methylbutyryl-CoA: 0.0
ctg1_2533: pk - Gly
  Search NORINE for peptide: strict or relaxed
  CAL_domain (60..471): pk
  minowa: fatty_acid
  Prediction, score:
    fatty_acid: 15.0
    NH2: 10.3
    shikimic_acid: 0.0
    Acetyl-CoA: 0.0
    AHBA: 0.0
  AMP-binding (1159..1554): Gly
  nrpys: Gly
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
    Small clusters prediction:
      Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
    Single AA prediction:
      gly (Gly)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DILQLGMIWK
    Nearest Stachelhaus code(s):
      Gly DILQLGMIWK (100% 8Å match)
    Stachelhaus code match:
      100% (strong)
ctg1_2536: Ala
  Search NORINE for peptide: strict or relaxed
  AMP-binding (497..905): Ala
  nrpys: Ala
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      N/A
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVSNMAIIYK
    Nearest Stachelhaus code(s):
      Ala DVSNMAIIYK (91% 8Å match)
    Stachelhaus code match:
      100% (strong)

gnlProkkaPNOABPKD_1 - Region 8 - NRPS,betalactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,711,427 - 2,789,190 nt. (total: 77,764 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))
betalactone: (HMGL-like and AMP-binding)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
KnownClusterBlast
NRPS/PKS modules
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate cluster in NRPS and PKS regions.
Genes are shown in predicted order, and are only present when containing at least one complete module.
A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
NRPS/PKS products
NRPS/PKS substrates
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 8, location 2711426 - 2789190:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (Glu - D-Orn) + (Tyr - D-Thr) + (Glu - D-Val) + (Pro - Glu - D-Tyr) + (Ile)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS substrate predictions
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_2653: X
  AMP-binding (13..445): X
  nrpys: Asp, Asn, Glu, Gln, Aad
  SVM prediction details:
    Predicted physicochemical class:
      N/A
    Large clusters prediction:
      Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      -GLHIAAPVK
    Nearest Stachelhaus code(s):
      Z-ahmohOrn FGLHIASTCK (56% 8Å match)
      Ile DGLFIGIPVK (32% 8Å match)
    Stachelhaus code match:
      60% (weak)
ctg1_2658: Ile
  Search NORINE for peptide: strict or relaxed
  AMP-binding (474..867): Ile
  nrpys: Ile
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
    Small clusters prediction:
      Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
    Single AA prediction:
      ile (Ile)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAFFYGITFK
    Nearest Stachelhaus code(s):
      Ile DAFFYGITFK (100% 8Å match)
    Stachelhaus code match:
      100% (strong)
ctg1_2659: Pro - Glu - Tyr
  Search NORINE for peptide: strict or relaxed
  AMP-binding (469..866): Pro
  nrpys: Pro
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      Cyclic aliphatic chain (polar NH2 group) (Pro, Hpr)
    Small clusters prediction:
      pro (Pro)
    Single AA prediction:
      pro (Pro)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVQFIAHVVK
    Nearest Stachelhaus code(s):
      Pro DVQFIAHVVK (100% 8Å match)
    Stachelhaus code match:
      100% (strong)
  AMP-binding (1500..1901): Glu
  nrpys: Glu
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
    Large clusters prediction:
      Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
    Small clusters prediction:
      glu,gln (Glu, Gln)
    Single AA prediction:
      glu (Glu)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAWHFGSVEK
    Nearest Stachelhaus code(s):
      Glu DAWHFGSVEK (100% 8Å match)
      Gln DAWHFGSVEK (94% 8Å match)
    Stachelhaus code match:
      100% (strong)
  AMP-binding (2539..2933): Tyr
  nrpys: Tyr
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
    Large clusters prediction:
      Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
    Small clusters prediction:
      Polar aromatic ring (Tyr, bOH-Tyr)
    Single AA prediction:
      tyr (Tyr)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DGTITAEVAK
    Nearest Stachelhaus code(s):
      Tyr DGTITAEVAK (97% 8Å match)
    Stachelhaus code match:
      100% (strong)
ctg1_2660: Glu - Val
  Search NORINE for peptide: strict or relaxed
  AMP-binding (469..870): Glu
  nrpys: Glu
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
    Large clusters prediction:
      Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
    Small clusters prediction:
      glu,gln (Glu, Gln)
    Single AA prediction:
      glu (Glu)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAWHFGGVDK
    Nearest Stachelhaus code(s):
      Glu DAWHFGGVDK (100% 8Å match)
    Stachelhaus code match:
      100% (strong)
  AMP-binding (1510..1903): Val
  nrpys: Val
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
    Small clusters prediction:
      Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
    Single AA prediction:
      val (Val)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVFWIGGTFK
    Nearest Stachelhaus code(s):
      Val DVFWIGGTFK (100% 8Å match)
      Ala or Val DVFWIGGTFK (91% 8Å match)
    Stachelhaus code match:
      100% (strong)
ctg1_2661: Tyr - Thr
  Search NORINE for peptide: strict or relaxed
  AMP-binding (474..865): Tyr
  nrpys: Tyr
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
    Large clusters prediction:
      Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
    Small clusters prediction:
      Polar aromatic ring (Tyr, bOH-Tyr)
    Single AA prediction:
      tyr (Tyr)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DGTITAEVAK
    Nearest Stachelhaus code(s):
      Tyr DGTITAEVAK (100% 8Å match)
    Stachelhaus code match:
      100% (strong)
  AMP-binding (1505..1903): Thr
  nrpys: Thr
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      Aliphatic chain or phenyl group with -OH (Ser, Thr, Dhpg, Hpg)
    Small clusters prediction:
      thr (Thr)
    Single AA prediction:
      thr (Thr)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DFWNIGMVHK
    Nearest Stachelhaus code(s):
      Thr DFWNIGMVHK (100% 8Å match)
    Stachelhaus code match:
      100% (strong)
ctg1_2662: Glu - Orn
  Search NORINE for peptide: strict or relaxed
  AMP-binding (463..864): Glu
  nrpys: Glu
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
    Large clusters prediction:
      Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
    Small clusters prediction:
      glu,gln (Glu, Gln)
    Single AA prediction:
      glu (Glu)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAWHFGGVDK
    Nearest Stachelhaus code(s):
      Glu DAWHFGGVDK (100% 8Å match)
    Stachelhaus code match:
      100% (strong)
  AMP-binding (1503..1908): Orn
  nrpys: Orn
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
    Large clusters prediction:
      Long positively charged side chain (Orn, Lys, Arg)
    Small clusters prediction:
      Orn and hydroxy-Orn specific (Orn, OH-Orn)
    Single AA prediction:
      orn (Orn)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVGEIGSIDK
    Nearest Stachelhaus code(s):
      Orn DVGEIGSIDK (100% 8Å match)
    Stachelhaus code match:
      100% (strong)

gnlProkkaPNOABPKD_1 - Region 9 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,846,035 - 2,867,933 nt. (total: 21,899 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

gnlProkkaPNOABPKD_1 - Region 10 - lanthipeptide-class-ii
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,889,491 - 2,912,376 nt. (total: 22,886 nt) Show pHMM detection rules used
lanthipeptide-class-ii: cds(LANC_like and DUF4135)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Lanthipeptides
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.

#### Lanthipeptide(s) for ctg1_2797

ctg1_2788
Leader:
MIAKMMEALDGERFDIIMEKTLKGM
Core:
TRVMIWGCLPYFLYVLIRMFTN
Core with dehydrations:
DhbRVMIWGCysLPYFLYVLIRMFDhbN

#### antiSMASH-DB 4.0 matches for ctg1_2788

100.0% NZ_CP026035.1: Lanthipeptides: C2H96_RS00360_lanthipeptide
1
TRVMIWGCLPYFLYVLIRMFTN
22
TRVMIWGCLPYFLYVLIRMFTN
1
TRVMIWGCLPYFLYVLIRMFTN
22
15.6% NZ_JANYMP010000042.1: Lanthipeptides: allorf_39377_39523_lanthipeptide
3
VMIWGCLPYFLYVLIRMFTN
22
+WGC P+ R ++
5
AGMWGCYPHAHDGRGREDSD
24
ctg1_2798
Leader:
MTKETIIGISMKSLSREEMNNLFGG
Core:
NGADADVRSTPICSAGISFIATYLGSAATNCGKDNKK
Core with dehydrations:
NGADADVRDhaDhbPICysDhaAGIDhaFIADhbYLGDhaAADhbNCysGKDNKK

#### antiSMASH-DB 4.0 matches for ctg1_2798

100.0% NZ_CP026035.1: Lanthipeptides: C2H96_RS00310_lanthipeptide
1
NGADADVRSTPICSAGISFIATYLGSAATNCGKDNKK
37
NGADADVRSTPICSAGISFIATYLGSAATNCGKDNKK
1
NGADADVRSTPICSAGISFIATYLGSAATNCGKDNKK
37
70.3% NC_003028.3 and 45 others:
NC_003098.1 Lanthipeptides: SPR_RS08865_lanthipeptide NC_011900.1 Lanthipeptides: SPN23F_RS10050_lanthipeptide NC_012466.1 Lanthipeptides: SPJ_RS09635_lanthipeptide NZ_CFDV01000030.1 Lanthipeptides: AQB43_RS08320_lanthipeptide NZ_CFVJ01000005.1 Lanthipeptides: AP598_RS03265_lanthipeptide NZ_CGGJ01000006.1 Lanthipeptides: AP607_RS03205_lanthipeptide NZ_CHVQ01000007.1 Lanthipeptides: AQF85_RS04285_lanthipeptide NZ_CJZM01000008.1 Lanthipeptides: AEE29_RS04155_lanthipeptide NZ_CLHL01000007.1 Lanthipeptides: AE723_RS05750_lanthipeptide NZ_CMIW01000004.1 Lanthipeptides: AD046_RS04075_lanthipeptide NZ_CMKL01000017.1 Lanthipeptides: AD734_RS09110_lanthipeptide NZ_CP035244.1 Lanthipeptides: EQH36_RS09105_lanthipeptide NZ_CP035253.1 Lanthipeptides: EQH27_RS09740_lanthipeptide NZ_CP082820.1 Lanthipeptides: K8B76_RS08865_lanthipeptide NZ_CPPE01000023.1 Lanthipeptides: AD654_RS06875_lanthipeptide NZ_CPRX01000013.1 Lanthipeptides: AEE77_RS05820_lanthipeptide NZ_CPTT01000011.1 Lanthipeptides: AEH42_RS06000_lanthipeptide NZ_CRAW01000006.1 Lanthipeptides: AK725_RS04395_lanthipeptide NZ_CRXO01000010.1 Lanthipeptides: AKU38_RS05260_lanthipeptide NZ_FCRW01000008.1 Lanthipeptides: A1N73_RS07425_lanthipeptide NZ_FDDE01000015.1 Lanthipeptides: A1A23_RS09705_lanthipeptide NZ_FDFR01000008.1 Lanthipeptides: A1O50_RS09320_lanthipeptide NZ_FDGF01000009.1 Lanthipeptides: A0899_RS06595_lanthipeptide NZ_FDQP01000009.1 Lanthipeptides: A1S42_RS08050_lanthipeptide NZ_FECM01000008.1 Lanthipeptides: A1930_RS06475_lanthipeptide NZ_FEEQ01000001.1 Lanthipeptides: A1T31_RS01145_lanthipeptide NZ_FEOS01000003.1 Lanthipeptides: A1178_RS03085_lanthipeptide NZ_FFTU01000009.1 Lanthipeptides: A1K37_RS06335_lanthipeptide NZ_FHJP02000011.1 Lanthipeptides: A1O79_RS07375_lanthipeptide NZ_FHRS02000028.1 Lanthipeptides: A1898_RS09820_lanthipeptide NZ_FIXQ01000010.1 Lanthipeptides: AZ721_RS04790_lanthipeptide NZ_FZDX01000018.1 Lanthipeptides: CFW91_RS09480_lanthipeptide NZ_FZEI01000008.1 Lanthipeptides: CFW58_RS06410_lanthipeptide NZ_JACVHZ010000010.1 Lanthipeptides: ICJ99_RS03880_lanthipeptide NZ_JAGFAE010000038.1 Lanthipeptides: J5E60_RS09005_lanthipeptide NZ_JALDUX010000010.1 Lanthipeptides: M1F92_RS09535_lanthipeptide NZ_JAMYJM010000002.1 Lanthipeptides: NKE69_RS04885_lanthipeptide NZ_LR216014.1 Lanthipeptides: E0F05_RS09385_lanthipeptide NZ_LR216016.1 Lanthipeptides: E0F10_RS10160_lanthipeptide NZ_LR216019.1 Lanthipeptides: E0E94_RS09635_lanthipeptide NZ_LR216027.1 Lanthipeptides: E0E81_RS09205_lanthipeptide NZ_LR216049.1 Lanthipeptides: E0E96_RS09540_lanthipeptide NZ_LR216064.1 Lanthipeptides: E0F31_RS09525_lanthipeptide NZ_LR536843.1 Lanthipeptides: E0F34_RS09600_lanthipeptide NZ_NANQ01000003.1 Lanthipeptides: B5K28_RS01935_lanthipeptide
Lanthipeptides: SP_RS09795_lanthipeptide
5
ADVRSTPICSAGISFIATYLGSAATNCGKDNKK
37
AD RST ICSA +SFIA+YLGSA T CGKDNKK
4
ADPRSTIICSATLSFIASYLGSAQTRCGKDNKK
36
70.3% NZ_NAOJ01000022.1: Lanthipeptides: B5K31_RS08015_lanthipeptide
5
ADVRSTPICSAGISFIATYLGSAATNCGKDNKK
37
AD RST ICSA +SFIA+YLGSA T CGKDNKK
4
ADPRSTTICSATLSFIASYLGSAQTRCGKDNKK
36
with 24 more sequence matches
67.6% NZ_MRXY01000010.1: Lanthipeptides: BTU63_RS06305_lanthipeptide
5
ADVRSTPICSAGISFIATYLGSAATNCGKDNKK
37
AD RS+ ICSA +SFIA+YLGSA T CGKDNKK
4
ADPRSSIICSATLSFIASYLGSAQTRCGKDNKK
36
64.9% NZ_LN884299.1: Lanthipeptides: BN2762_RS08665_lanthipeptide
2
GADADVRSTPICSAGISFIATYLGSAATNCGKDNK
36
G DA+VRST +C GISF+A+YL SAA CGKDNK
2
GMDAEVRSTLLCGMGISFVASYLASAAFKCGKDNK
36
63.2% NZ_LWAG01000079.1: Lanthipeptides: A4R27_RS25235_lanthipeptide
1
NGADADVRSTPICSAGISFIATYLGSAATNCGKDNK
36
+G DA+ RST IC AGIS I +YL SAA CGKDNK
1
SGMDAEARSTLICGAGISLIGSYLASAAFKCGKDNK
36
62.2% NZ_CP094446.1: Lanthipeptides: L3476_RS23820_lanthipeptide
1
NGADADVRSTPICSAGISFIATYLGSAATNCGKDNKK
37
+G D +VRST IC G SFI +YL SAA CGK NKK
1
DGMDVEVRSTLICGVGASFIGSYLASAAFKCGKKNKK
37
59.5% NZ_CP041405.1: Lanthipeptides: FLT43_RS14405_lanthipeptide
1
NGADADVRSTPICSAGISFIATYLGSAATNCGKDNK
36
NG D +VRS+ +C AGIS++A+YL SAA CGK NK
1
NGMDVEVRSSLVCGAGISYVASYLASAAFKCGKKNK
36
56.8% NZ_JACSNF010000005.1 and 1 other:
NZ_LMPR01000013.1 Lanthipeptides: ASF99_RS16385_lanthipeptide
Lanthipeptides: KNQ12_RS14670_lanthipeptide
4
DADVRSTPICSAGISFIATYLGSAATNCGKDNKK
37
D DVRS+ +CSA +SF+ +YL SA CGKDNKK
3
DVDVRSSLVCSALLSFVGSYLASAGLKCGKDNKK
36
52.6% NZ_CP084237.1: Lanthipeptides: RES5_RS11640_lanthipeptide
3
ADADVRSTPICSAGI-SFIAT----YLGSAATNCGKDNKK
37
++ ++R TP + GI SF+AT Y SAA CGKDNKK
1
SEVELRGTP--TIGIASFVATIPTGYTASAAFKCGKDNKK
38
43.2% NZ_JACSPZ010000014.1: Lanthipeptides: H9635_RS18395_lanthipeptide
2
GADADVRSTPICSAGISFIATYLGSAATNCGKDNK
36
G++ +STP+CS F+A+Y+ SA CG DNK
2
GSEIQPQSTPLCS----FLASYIISAQFKCGGDNK
32
40.5% NZ_FNYB01000021.1: Lanthipeptides: BMZ34_RS24355_lanthipeptide
1
NGADADVRSTPICSAGISFIATYLGSAATNCGKDNK
36
+G D +P+ + SF+A+Y+ SA CGKDNK
1
SGVDPRTTPSPLLA---SFVASYIASAEFRCGKDNK
33
40.5% NZ_FNYB01000021.1: Lanthipeptides: BMZ34_RS24360_lanthipeptide
1
NGADADVRSTPICSAGISFIATYLGSAATNCGKDNK
36
+G D +P+ + SF+A+Y+ SA CGKDNK
1
SGVDPRTTPSPLLA---SFVASYIASAQYRCGKDNK
33
40.5% NZ_KB976303.1: Lanthipeptides: IGY_RS26050_lanthipeptide
1
NGADADVRSTPICSAGISFIATYLGSAATNCGKDNK
36
+G D +P+ + SF+A+Y+ SA CGKDNK
1
SGVDPRTTPSPLLA---SFVASYIASAQFRCGKDNK
33
40.5% NZ_KN125582.1: Lanthipeptides: DJ91_RS27545_lanthipeptide
8
RSTPICSAGISFIATYLGSAATNCGKDNK
36
R+TP + SF+A+Y+ SA CGKDNK
6
RTTPATTLLASFVASYIASAEFRCGKDNK
34
40.5% NZ_NVMQ01000017.1: Lanthipeptides: CON32_RS17790_lanthipeptide
1
NGADADVRSTPICSAGISFIATYLGSAATNCGKDNK
36
+G D +P+ + SF+A+Y+ SA CGKDNK
1
SGVDPRTTPSPLLA---SFVASYIASAEFKCGKDNK
33
32.4% NZ_JQBU01000033.1 and 1 other:
NZ_JQBV01000009.1 Lanthipeptides: IV76_RS12120_lanthipeptide
Lanthipeptides: IV75_RS14620_lanthipeptide
4
DADVRSTPICSAGISFIATYLGSAATNCGK
33
D STPIC AG + + + +G T GK
2
DVMPESTPIC-AGFATLMSSIGLVKTIKGK
30
27.0% NZ_CP086395.1 and 1 other:
NZ_JAKTAW010000012.1 Lanthipeptides: MKK30_RS11185_lanthipeptide
Lanthipeptides: LMK00_RS10670_lanthipeptide
4
DADVRSTPIC--SAGIS
18
D +VRSTPIC +AG++
2
DVEVRSTPICTFTAGVT
18
27.0% NZ_JAQDYA010000001.1: Lanthipeptides: PGT72_RS00020_lanthipeptide
4
DADVRSTPICSA------GISFIATYLG
25
D STP+C+A GI+ + T G
2
DITPESTPVCAAFATLASGIALVKTIKG
29
25.0% NZ_MIFM01000001.1 and 1 other:
NZ_NINI01000009.1 Lanthipeptides: CEV12_RS07280_lanthipeptide
Lanthipeptides: BHL22_RS00425_lanthipeptide
4
DADVRSTPICSAGISFIATYLGSAATNCG
32
D +TP+C+ +AT SAA CG
2
DVQAETTPVCAVS---VATMTSSAA--CG
25
22.2% NZ_CP026035.1: Lanthipeptides: C2H96_RS00305_lanthipeptide
3
ADADVRSTPICSAGISFI
20
ADAD R TP SA +S +
1
ADADPRWTPAVSAVLSAV
18
21.1% NZ_CP010976.1: Lanthipeptides: UB51_RS20980_lanthipeptide
9
STPICSAGISFIATYLGSAATNCGK
33
+TP S +S I +++G+A + K
13
ATPALSKAVSAIVSFVGTAIVSIAK
37
18.2% NZ_GG730336.1: Lanthipeptides: SAUG_RS08760_lanthipeptide
12
ICSAGISFIATYLGSAATNC
31
+ +AG SF+ +++ SA +NC
24
VSAAGASFVTSFVASATSNC
43
16.2% NZ_JAEKEJ010000007.1: Lanthipeptides: JFU02_RS02775_lanthipeptide
4
DADVRSTPICSAG
16
D +TPIC+ G
2
DVQPETTPICAFG
14
14.9% NZ_LMFT01000038.1: Lanthipeptides: allorf_010542_010721_lanthipeptide
13
CSAGISFIATYLGSAA
28
CS F +Y GSA+
1
CSRATQFPYSYSGSAS
16
13.2% NC_014098.1: Lanthipeptides: BTUS_RS14195_lanthipeptide
4
DADVRSTPICSAGISFI
20
D STP+C+ G+ F+
23
DVQAESTPLCAFGVGFL
39
11.4% NZ_KB946334.1: Lanthipeptides: UC7_RS10240_lanthipeptide
3
ADADVRSTPIC
13
D V +TP+C
1
GDVQVETTPVC
11
ctg1_2799
Leader:
MENKSIVEKSCGKSMKSLSLEEMSTIYGA
Core:
ADADPRWTPAVSAVLSAVGRSTRLCISGIGSAISGIVSHNKDCLG
Core with dehydrations:
ADADPRWDhbPAVDhaAVLDhaAVGRDhaDhbRLCysIDhaGIGDhaAIDhaGIVDhaHNKDCysLG

#### MIBiG 3.1 matches for ctg1_2799

13.3% BGC0000582 (ADR72962.1): Linaridin: cypemycin
8
TPAVSAVLSAVGRSTRLCI
26
TPA V V + + +C+
2
TPATPTVAQFVIQGSTICL
20

#### antiSMASH-DB 4.0 matches for ctg1_2799

100.0% NZ_CP026035.1: Lanthipeptides: C2H96_RS00305_lanthipeptide
1
ADADPRWTPAVSAVLSAVGRSTRLCISGIGSAISGIVSHNKDCLG
45
ADADPRWTPAVSAVLSAVGRSTRLCISGIGSAISGIVSHNKDCLG
1
ADADPRWTPAVSAVLSAVGRSTRLCISGIGSAISGIVSHNKDCLG
45
66.7% NZ_CP094446.1: Lanthipeptides: L3476_RS23825_lanthipeptide
1
ADADPRWTPAVSAVLSAVGRSTRLCISGIGSAISGIVSHNKDCLG
45
+D +PR TPA ++SAV RS++ CIS IGSAISGI+SHNKDCLG
1
SDVEPRGTPAT--IVSAVTRSSKPCISAIGSAISGIISHNKDCLG
43
62.2% NZ_JACSNF010000005.1 and 1 other:
NZ_LMPR01000013.1 Lanthipeptides: ASF99_RS16390_lanthipeptide
Lanthipeptides: KNQ12_RS14665_lanthipeptide
1
ADADPRWTPAVSAVLSAVGRSTRLCISGIGSAISGIVSHNKDCLG
45
+D DPRWTP +S V ++ +ST+ CI SAISGIVSHNKDCLG
1
SDVDPRWTPVISLVARSIVKSTKACIGAGASAISGIVSHNKDCLG
45
with 28 more sequence matches
57.8% NZ_LWAG01000079.1: Lanthipeptides: A4R27_RS25230_lanthipeptide
1
ADADPRWTPAVSAVLSAVGRSTRLCISGIGSAISGIVSHNKDCLG
45
+D DPRWTP SA +++ RS+++CIS +GSAI GIVS+NK+C G
1
SDVDPRWTPIASAAINSAARSSKICISAVGSAIGGIVSYNKNCAG
45
56.5% NZ_LN884299.1: Lanthipeptides: BN2762_RS08660_lanthipeptide
1
ADADPRWTPA-VSAVLSAVGRSTRLCISGIGSAISGIVSHNKDCLG
45
+D DPR TP V++++ +V +S+++CIS +GSAISGIVS+NK+CLG
1
SDVDPRATPTIVASIIRSVAQSSKVCISAVGSAISGIVSNNKNCLG
46
52.2% NZ_CP041405.1: Lanthipeptides: FLT43_RS14400_lanthipeptide
1
ADADPRWTPA-VSAVLSAVGRSTRLCISGIGSAISGIVSHNKDCLG
45
+D +PR TP V A+ +AV S+++C+S + SAI GI SHN DCLG
1
SDVEPRATPTIVPAISAAVRTSSKVCLSLVASAIGGIASHNNDCLG
46
51.1% NZ_KN125582.1: Lanthipeptides: DJ91_RS27550_lanthipeptide
4
DPRWTPAVSAVLSAVGRSTRLCISGIGSAISGIVSHNKDCLG
45
D R P V V+S + S+ C S I SAISG+VS+NKDCLG
4
DTRTHPTV-IVVSRI--SSAKCASTI-SAISGLVSYNKDCLG
41
48.9% NZ_JACSPZ010000014.1: Lanthipeptides: H9635_RS18390_lanthipeptide
4
DPRWTPAVSAVLSAVGRSTRLCISGIGSAISGIVSHNKDCLG
45
+P TP +LSA +S++ C+ I SAISG+VS+NKDCLG
5
EPHTTP----ILSAATKSSKKCLGAI-SAISGLVSYNKDCLG
41
48.9% NZ_JAMYJM010000002.1: Lanthipeptides: NKE69_RS04880_lanthipeptide
3
ADPRWTPAVSAVLSAVGRSTRLCISGIGSAISGIVSHNKDCLG
45
A+PRWTP +L + S+++CIS + S I GIVS+N DCLG
4
AEPRWTP-TPFILKSATASSKVCISAVVSGIGGIVSYNNDCLG
45
48.9% NZ_MRXY01000010.1: Lanthipeptides: BTU63_RS06300_lanthipeptide
3
ADPRWTPAVSAVLSAVGRSTRLCISGIGSAISGIVSHNKDCLG
45
A+P WTP +L + RS+++CIS I S I GI S+N DCLG
4
AEPLWTP-TPTILKSAARSSKVCISAIISGIGGIFSYNNDCLG
45
46.7% NC_003028.3 and 39 others:
NC_003098.1 Lanthipeptides: SPR_RS08860_lanthipeptide NC_011900.1 Lanthipeptides: SPN23F_RS10045_lanthipeptide NC_012466.1 Lanthipeptides: SPJ_RS09630_lanthipeptide NZ_CFDV01000030.1 Lanthipeptides: AQB43_RS08315_lanthipeptide NZ_CFVJ01000005.1 Lanthipeptides: AP598_RS03270_lanthipeptide NZ_CGGJ01000006.1 Lanthipeptides: AP607_RS03210_lanthipeptide NZ_CHVQ01000007.1 Lanthipeptides: AQF85_RS04280_lanthipeptide NZ_CJZM01000008.1 Lanthipeptides: AEE29_RS04150_lanthipeptide NZ_CLHL01000007.1 Lanthipeptides: AE723_RS05755_lanthipeptide NZ_CMIW01000004.1 Lanthipeptides: AD046_RS04070_lanthipeptide NZ_CP035253.1 Lanthipeptides: EQH27_RS09735_lanthipeptide NZ_CP082820.1 Lanthipeptides: K8B76_RS08860_lanthipeptide NZ_CPRX01000013.1 Lanthipeptides: AEE77_RS05815_lanthipeptide NZ_CPTT01000011.1 Lanthipeptides: AEH42_RS06005_lanthipeptide NZ_CRAW01000006.1 Lanthipeptides: AK725_RS04390_lanthipeptide NZ_CRXO01000010.1 Lanthipeptides: AKU38_RS05255_lanthipeptide NZ_FCRW01000008.1 Lanthipeptides: A1N73_RS07430_lanthipeptide NZ_FDDE01000015.1 Lanthipeptides: A1A23_RS09710_lanthipeptide NZ_FDFR01000008.1 Lanthipeptides: A1O50_RS09315_lanthipeptide NZ_FDGF01000009.1 Lanthipeptides: A0899_RS06590_lanthipeptide NZ_FDQP01000009.1 Lanthipeptides: A1S42_RS08045_lanthipeptide NZ_FECM01000008.1 Lanthipeptides: A1930_RS06470_lanthipeptide NZ_FEEQ01000001.1 Lanthipeptides: A1T31_RS01150_lanthipeptide NZ_FEOS01000003.1 Lanthipeptides: A1178_RS03090_lanthipeptide NZ_FFTU01000009.1 Lanthipeptides: A1K37_RS06340_lanthipeptide NZ_FHRS02000028.1 Lanthipeptides: A1898_RS09825_lanthipeptide NZ_FIXQ01000010.1 Lanthipeptides: AZ721_RS04795_lanthipeptide NZ_FZDX01000018.1 Lanthipeptides: CFW91_RS09485_lanthipeptide NZ_FZEI01000008.1 Lanthipeptides: CFW58_RS06405_lanthipeptide NZ_JACVHZ010000010.1 Lanthipeptides: ICJ99_RS03885_lanthipeptide NZ_JAGFAE010000038.1 Lanthipeptides: J5E60_RS09010_lanthipeptide NZ_LR216014.1 Lanthipeptides: E0F05_RS09380_lanthipeptide NZ_LR216019.1 Lanthipeptides: E0E94_RS09630_lanthipeptide NZ_LR216027.1 Lanthipeptides: E0E81_RS09200_lanthipeptide NZ_LR216049.1 Lanthipeptides: E0E96_RS09535_lanthipeptide NZ_LR216064.1 Lanthipeptides: E0F31_RS09520_lanthipeptide NZ_LR536843.1 Lanthipeptides: E0F34_RS09595_lanthipeptide NZ_NANQ01000003.1 Lanthipeptides: B5K28_RS01930_lanthipeptide NZ_NAOJ01000022.1 Lanthipeptides: B5K31_RS08010_lanthipeptide
Lanthipeptides: SP_RS09790_lanthipeptide
3
ADPRWTPAVSAVLSAVGRSTRLCISGIGSAISGIVSHNKDCLG
45
A+PRWTP +L + S+++CIS S I G+VS+N DCLG
4
AEPRWTP-TPIILKSAAASSKVCISAAVSGIGGLVSYNNDCLG
45
46.7% NZ_CP035244.1 and 3 others:
NZ_CPPE01000023.1 Lanthipeptides: AD654_RS06870_lanthipeptide NZ_FHJP02000011.1 Lanthipeptides: A1O79_RS07380_lanthipeptide NZ_LR216016.1 Lanthipeptides: E0F10_RS10155_lanthipeptide
Lanthipeptides: EQH36_RS09100_lanthipeptide
3
ADPRWTPAVSAVLSAVGRSTRLCISGIGSAISGIVSHNKDCLG
45
A+PRWTP +L + S+++CIS S I G+VS+N DCLG
4
AEPRWTP-TPIILKSAAASSKICISAAVSGIGGLVSYNNDCLG
45
46.7% NZ_JALDUX010000010.1: Lanthipeptides: M1F92_RS09530_lanthipeptide
3
ADPRWTPAVSAVLSAVGRSTRLCISGIGSAISGIVSHNKDCLG
45
A+PRWTP +L + S+++CIS + S I G+VS+N DCLG
4
AEPRWTP-TPLILKSAAASSKVCISALVSGIGGLVSYNNDCLG
45
46.7% NZ_KB976303.1 and 1 other:
NZ_KB976303.1 Lanthipeptides: IGY_RS26035_lanthipeptide
Lanthipeptides: IGY_RS26045_lanthipeptide
4
DPRWTPAVSAVLSAVGRSTRLCISGIGSAISGIVSHNKDCLG
45
D R P V V A S++ C+SG+ SAISG++S+NKDC+G
4
DTRTHPTVIVVSRA---SSKACMSGV-SAISGLLSYNKDCIG
41
33.3% NZ_CMKL01000017.1: Lanthipeptides: AD734_RS09115_lanthipeptide
3
ADPRWTPAVSAVLSAVGRSTRLCISGIGSAISGI
36
A+PRWTP +L + S+++CIS +A+SGI
4
AEPRWTP-TPIILKSAAASSKVCIS---AAVSGI
33
33.3% NZ_JAQDYA010000001.1: Lanthipeptides: PGT72_RS00025_lanthipeptide
2
DADPRWTPAVSAVLSAVGRSTRLCISGIGSAISGIVSHNKDC
43
D P TP +A ++ S+ C +G SA+SGIV C
2
DITPETTPVCAATVA----SSAYC-AGAASAVSGIVLSVFKC
38
31.1% NZ_GG730336.1: Lanthipeptides: SAUG_RS08755_lanthipeptide
4
DPRWTPAVSAVLSAVGRSTRLCISGIGSAISGIVSHNKDCL
44
+P+ TP +++ + + + I SA+SG+VS+ KDCL
5
EPQATPTIASPFTP--YAIEISIGATVSAVSGLVSYTKDCL
43
28.9% NZ_KB976303.1: Lanthipeptides: IGY_RS26040_lanthipeptide
3
ADPRWTPAVSAVLSAVGRSTRLCISGIGSAISGIVSHNKD
42
D R P V V A S++ C++ +GS ++S+N D
3
VDTRTHPTVVVVSRA---SSKFCVTVVGSV---LLSYNMD
36
24.4% NZ_CP013862.1 and 1 other:
NZ_CP013862.1 Lanthipeptides: AOX59_RS09365_lanthipeptide
Lanthipeptides: AOX59_RS09365_lanthipeptide
2
DADPRWTP-------AVSAVLSAVGRSTRLC
25
D DP+ TP AVSA+ + T C
2
DVDPQTTPSSVACGIAVSALFCPTTKCTSQC
32
22.2% NZ_CP015405.2 and 1 other:
NZ_CP053228.1 Lanthipeptides: HL650_RS06245_lanthipeptide
Lanthipeptides: A4V09_RS08280_lanthipeptide
21
STRLCISGIGSAISGIVSHNKD
42
S LC SG +A G S KD
3
SISLCTSGCKTAFFGTCSFTKD
24
22.2% NZ_CP026035.1: Lanthipeptides: C2H96_RS00310_lanthipeptide
1
ADADPRWTPAVSAVLSAV
18
ADAD R TP SA +S +
3
ADADVRSTPICSAGISFI
20
22.2% NZ_CP101913.1 and 1 other:
NZ_CP101913.1 Lanthipeptides: NP440_RS09140_lanthipeptide
Lanthipeptides: NP440_RS09140_lanthipeptide
3
ADPRWTPAVSAVLSAVGRSTRLCIS
27
A+P+ TP V+ +SA T C S
2
AEPQGTPTVTIPISAAICPTTQCAS
26
22.2% NZ_JAMDLZ010000027.1: Lanthipeptides: M5W82_RS15520_lanthipeptide
1
ADADPRWTP-AVSAVLSAVGRSTRLCIS
27
++ P+WTP V+ +S G T C S
1
SEIQPKWTPLTVTIPISLAGCPTTKCAS
28
21.6% NZ_CP040414.1: Lanthipeptides: FE331_RS05905_lanthipeptide
13
AVLSAVGRSTRLCISGIGSAISGIVSHNKDC
43
AV V S + C I SA++ +S N+ C
13
AVTPVVSASLKFCAPAI-SAVTTFLSCNRSC
42
21.3% NZ_JAKVIH010000006.1 and 1 other:
NZ_JAQEOM010000007.1 Lanthipeptides: PGW12_RS04385_lanthipeptide
Lanthipeptides: MK858_RS03865_lanthipeptide
2
DADPRWTPAVSAVLSAVGRSTRLCISGIGSAISGIVSHNKDC
43
+ PR TP V+ + IS + ++S V+ + C
3
EVQPRSTPTVTV---PIATPELTAISALTVSVSNFVTKYRSC
41
20.0% NZ_MSTN01000008.1: Lanthipeptides: BVF97_RS19710_lanthipeptide
2
DADPRWTPAVSAVLSAVGRSTRLC
25
D P TP + +LSAV + C
2
DVTPYSTPGCAMLLSAVWATITKC
25
15.6% NZ_CP016020.1 and 34 others:
NZ_CP067069.1 Lanthipeptides: JCR32_RS24625_lanthipeptide NZ_CP085413.1 Lanthipeptides: LIS80_RS25380_lanthipeptide NZ_CP085413.1 Lanthipeptides: LIS80_RS25375_lanthipeptide NZ_CP085413.1 Lanthipeptides: LIS80_RS25370_lanthipeptide NZ_CP085413.1 Lanthipeptides: LIS80_RS25365_lanthipeptide NZ_CP085413.1 Lanthipeptides: LIS80_RS25360_lanthipeptide NZ_CP085413.1 Lanthipeptides: LIS80_RS25355_lanthipeptide NZ_JH792105.1 Lanthipeptides: II5_RS26955_lanthipeptide NZ_LDKE01000067.1 Lanthipeptides: ABB04_RS19955_lanthipeptide NZ_LDKE01000067.1 Lanthipeptides: ABB04_RS19940_lanthipeptide NZ_LDKE01000067.1 Lanthipeptides: ABB04_RS19935_lanthipeptide NZ_MOOT01000061.1 Lanthipeptides: BK765_RS23995_lanthipeptide NZ_MOOT01000061.1 Lanthipeptides: BK765_RS23990_lanthipeptide NZ_NVEA01000001.1 Lanthipeptides: COL15_RS00005_lanthipeptide NZ_PIYQ01000022.1 Lanthipeptides: CW365_RS08185_lanthipeptide NZ_PIYQ01000022.1 Lanthipeptides: CW365_RS08180_lanthipeptide NZ_PIYQ01000022.1 Lanthipeptides: CW365_RS08175_lanthipeptide NZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20670_lanthipeptide NZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20665_lanthipeptide NZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20660_lanthipeptide NZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20655_lanthipeptide NZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20650_lanthipeptide NZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20645_lanthipeptide NZ_WBPC01000027.1 Lanthipeptides: F8159_RS19555_lanthipeptide NZ_WBPC01000027.1 Lanthipeptides: F8159_RS19550_lanthipeptide NZ_WBPC01000027.1 Lanthipeptides: F8159_RS19545_lanthipeptide NZ_WBPC01000027.1 Lanthipeptides: F8159_RS19540_lanthipeptide NZ_WBPC01000027.1 Lanthipeptides: F8159_RS19535_lanthipeptide NZ_WBPC01000027.1 Lanthipeptides: F8159_RS19530_lanthipeptide NZ_WBPE01000025.1 Lanthipeptides: F8161_RS14445_lanthipeptide NZ_WBPE01000025.1 Lanthipeptides: F8161_RS14440_lanthipeptide NZ_WBPK01000016.1 Lanthipeptides: F8167_RS15680_lanthipeptide NZ_WBPK01000016.1 Lanthipeptides: F8167_RS15675_lanthipeptide NZ_WBPK01000016.1 Lanthipeptides: F8167_RS15670_lanthipeptide
Lanthipeptides: A9C19_RS17970_lanthipeptide
1
ADADPRWTPAVSAVLSAVGRSTRLC
25
+D P TP V+ + S ++C
1
SDVQPETTPLCVGVIIGLTTSIKIC
25
15.6% NZ_CP067069.1 and 13 others:
NZ_CP085413.1 Lanthipeptides: LIS80_RS25350_lanthipeptide NZ_JH792105.1 Lanthipeptides: II5_RS26960_lanthipeptide NZ_JH792240.1 Lanthipeptides: IIK_RS26240_lanthipeptide NZ_MOOT01000061.1 Lanthipeptides: BK765_RS23985_lanthipeptide NZ_NTUF01000024.1 Lanthipeptides: CN379_RS26680_lanthipeptide NZ_NVCZ01000001.1 Lanthipeptides: COK75_RS01180_lanthipeptide NZ_NVDK01000008.1 Lanthipeptides: COK95_RS05665_lanthipeptide NZ_NVEA01000001.1 Lanthipeptides: COL15_RS00010_lanthipeptide NZ_PIYQ01000022.1 Lanthipeptides: CW365_RS08190_lanthipeptide NZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20675_lanthipeptide NZ_WBPC01000027.1 Lanthipeptides: F8159_RS19560_lanthipeptide NZ_WBPE01000025.1 Lanthipeptides: F8161_RS14435_lanthipeptide NZ_WBPK01000016.1 Lanthipeptides: F8167_RS15685_lanthipeptide
Lanthipeptides: JCR32_RS24620_lanthipeptide
1
ADADPRWTPAVSAVLSAVGRSTRLC
25
+D P TP V+ + S ++C
1
SDVQPETTPLCVGVIIGITASIKIC
25
15.6% NZ_CP084237.1: Lanthipeptides: RES5_RS11635_lanthipeptide
35
GIVSHNKDCLG
45
GIV++ K+CLG
6
GIVTYTKNCLG
16
15.6% NZ_LDKE01000067.1: Lanthipeptides: ABB04_RS19960_lanthipeptide
1
ADADPRWTPAVSAVLSAVGRSTRLC
25
+D P TP V+ + S ++C
1
SDVKPETTPLCVGVIIGITASIKIC
25
14.6% NZ_NVMQ01000017.1: Lanthipeptides: CON32_RS17795_lanthipeptide
37
VSHNKDCLG
45
VS+NK+CLG
40
VSYNKNCLG
48
allorf_2910520_2910690
Leader:
MGLGPHKMPYIVIRKDENSMYG
Core:
YSGYGYGFGCGTNTFVLIVVLFILLIIVGAAFIC
Core with dehydrations:
YDhaGYGYGFGCysGDhbNDhbFVLIVVLFILLIIVGAAFICys

#### MIBiG 3.1 matches for allorf_2910520_2910690

20.6% BGC0002110 (QKV49893.1): Lanthipeptide: birimositide
10
CGTNTFVLIVVL
21
C TNTF L L
1
CTTNTFSLSNAL
12

#### antiSMASH-DB 4.0 matches for allorf_2910520_2910690

23.5% NZ_CP047419.1 and 3 others:
NZ_CP047419.1 Lanthipeptides: GTU71_RS12805_lanthipeptide NZ_PSTO01000045.1 Lanthipeptides: C5C10_RS15590_lanthipeptide NZ_PSTO01000045.1 Lanthipeptides: C5C10_RS15590_lanthipeptide
Lanthipeptides: GTU71_RS12805_lanthipeptide
10
CGTNTFVLIVVL
21
C TNTF L VL
1
CTTNTFTLSNVL
12
20.6% NZ_CP080519.1: Lanthipeptides: K1T34_RS20225_lanthipeptide
3
GYGYGFGCGTNTFVLIVVLFILLIIV
28
G+G+G G +N +L L ++
1
GHGHGHGAPSNLSLLASCAHSTLSLL
26
16.7% NZ_CP110813.1: Lanthipeptides: allorf_3259340_3259546_lanthipeptide
5
GYGFGCGTNTFVLIVVL
21
GYGFGCG V L
15
GYGFGCGYRDHADSVSL
31
with 1 more sequence matches
12.2% NZ_CP011522.1: Lanthipeptides: allorf_5854327_5854506_lanthipeptide
10
CGTNTFVLI
18
CG+N FV++
24
CGSNPFVIV
32

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Lanthipeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

ctg1_2788 - Class II
  Cleavage pHMM score: -6.30
  RODEO score: 0
  Monoisotopic mass: 2699.4 Da
  Molecular weight: 2701.3 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2719.3 Da N = 1
ctg1_2798 - Class II
  Cleavage pHMM score: 1.50
  RODEO score: 0
  Monoisotopic mass: 3589.8 Da
  Molecular weight: 3592.0 Da
  Number of bridges: 2
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3610.0 Da N = 1
    3628.0 Da N = 2
    3646.0 Da N = 3
    3664.0 Da N = 4
    3682.1 Da N = 5
ctg1_2799 - Class II
  Cleavage pHMM score: 3.30
  RODEO score: 0
  Monoisotopic mass: 4345.3 Da
  Molecular weight: 4347.9 Da
  Number of bridges: 2
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    4365.9 Da N = 1
    4383.9 Da N = 2
    4402.0 Da N = 3
    4420.0 Da N = 4
    4438.0 Da N = 5
    4456.0 Da N = 6
    4474.0 Da N = 7
allorf_2910520_2910690 - Class II
  Cleavage pHMM score: -3.30
  RODEO score: 0
  Monoisotopic mass: 3548.9 Da
  Molecular weight: 3551.2 Da
  Number of bridges: 2
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3569.3 Da N = 1

gnlProkkaPNOABPKD_1 - Region 11 - T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,053,847 - 3,094,944 nt. (total: 41,098 nt) Show pHMM detection rules used
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
NRPS/PKS substrates
NRPS/PKS substrate predictions
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

gnlProkkaPNOABPKD_1 - Region 12 - NRP-metallophore,NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 4,036,045 - 4,087,822 nt. (total: 51,778 nt) Show pHMM detection rules used
NRP-metallophore: (VibH_like or Cy_tandem or (cds(Condensation and AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
KnownClusterBlast
NRPS/PKS modules
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate cluster in NRPS and PKS regions.
Genes are shown in predicted order, and are only present when containing at least one complete module.
A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
NRPS/PKS products
NRPS/PKS substrates
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 12, location 4036044 - 4087822:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (Gly - Thr)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS substrate predictions
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_4054: Gly - Thr
  Search NORINE for peptide: strict or relaxed
  AMP-binding (463..861): Gly
  nrpys: Gly
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
    Small clusters prediction:
      Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
    Single AA prediction:
      gly (Gly)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DILQLGLIWK
    Nearest Stachelhaus code(s):
      Gly DILQLGLIWK (100% 8Å match)
    Stachelhaus code match:
      100% (strong)
  AMP-binding (1519..1935): Thr
  nrpys: Thr
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      Aliphatic chain or phenyl group with -OH (Ser, Thr, Dhpg, Hpg)
    Small clusters prediction:
      thr (Thr)
    Single AA prediction:
      thr (Thr)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DFWNIGMVHK
    Nearest Stachelhaus code(s):
      Thr DFWNIGMVHK (100% 8Å match)
    Stachelhaus code match:
      100% (strong)
ctg1_4056: diOH-Bz
  Search NORINE for peptide: strict or relaxed
  AMP-binding (31..435): diOH-Bz
  nrpys: diOH-Bz
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
    Large clusters prediction:
      Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
    Small clusters prediction:
      Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
    Single AA prediction:
      dhb (diOH-Bz)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      PLPAQGVVNK
    Nearest Stachelhaus code(s):
      diOH-Bz PLPAQGVVNK (100% 8Å match)
      diOH-Bz or Sal PLPAQGVVNK (94% 8Å match)
    Stachelhaus code match:
      100% (strong)