LOCUS gnlProkkaMJFNDNHD_36 37591 bp DNA linear UNK 01-JAN-1980 DEFINITION gnl|Prokka|MJFNDNHD_36. ACCESSION gnlProkkaMJFNDNHD_36 VERSION gnlProkkaMJFNDNHD_36 KEYWORDS . SOURCE ORGANISM . COMMENT ##antiSMASH-Data-START## Version :: 7.1.0 Run date :: 2025-04-28 06:43:24 Original ID :: gnl|Prokka|MJFNDNHD_36 NOTE: This is a single region extracted from a larger record! Orig. start :: 0 Orig. end :: 37591 ##antiSMASH-Data-END## FEATURES Location/Qualifiers protocluster 1..37591 /aStool="rule-based-clusters" /category="NRPS" /contig_edge="True" /core_location="[2:17591]" /cutoff="20000" /detection_rule="cds(Condensation and (AMP-binding or A-OX))" /neighbourhood="20000" /product="NRPS" /protocluster_number="1" /tool="antismash" proto_core 3..17591 /aStool="rule-based-clusters" /tool="antismash" /cutoff="20000" /detection_rule="cds(Condensation and (AMP-binding or A-OX))" /neighbourhood="20000" /product="NRPS" /protocluster_number="1" cand_cluster 1..37591 /SMILES="NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CC(=O)O)C(=O)NC(CC (C)C)C(=O)NC(CC(C)C)C(=O)O" /candidate_cluster_number="1" /contig_edge="True" /detection_rules="cds(Condensation and (AMP-binding or A-OX))" /kind="single" /product="NRPS" /protoclusters="1" /tool="antismash" region 1..37591 /candidate_cluster_numbers="1" /contig_edge="True" /product="NRPS" /region_number="1" /rules="cds(Condensation and (AMP-binding or A-OX))" /tool="antismash" CDS 3..2966 /NRPS_PKS="Domain: AMP-binding (1-338). E-value: 3.6e-86. Score: 281.1. Matches aSDomain: nrpspksdomains_ctg23_1_AMP-binding.1" /NRPS_PKS="Domain: PCP (443-511). E-value: 5.9e-28. Score: 88.8. Matches aSDomain: nrpspksdomains_ctg23_1_PCP.1" /NRPS_PKS="Domain: Epimerization (521-824). E-value: 8.9e-178. Score: 584.4. Matches aSDomain: nrpspksdomains_ctg23_1_Epimerization.1" /NRPS_PKS="Domain: TIGR01720 (829-983). E-value: 1.3e-55. Score: 179.3. Matches aSDomain: nrpspksdomains_ctg23_1_TIGR01720.1" /gene_functions="biosynthetic (rule-based-clusters) NRPS: Condensation" /gene_functions="biosynthetic (rule-based-clusters) NRPS: AMP-binding" /gene_functions="biosynthetic-additional (rule-based-clusters) PP-binding" /gene_functions="biosynthetic-additional (smcogs) SMCOG1002:AMP-dependent synthetase and ligase (Score: 283.6; E-value: 4.1e-86)" /gene_kind="biosynthetic" /locus_tag="ctg23_1" /sec_met_domain="AMP-binding (E-value: 3.1e-99, bitscore: 326.2, seeds: 400, tool: rule-based-clusters)" /sec_met_domain="PP-binding (E-value: 2.4e-17, bitscore: 57.1, seeds: 164, tool: rule-based-clusters)" /sec_met_domain="Condensation (E-value: 1.3e-95, bitscore: 313.8, seeds: 42, tool: rule-based-clusters)" /transl_table=11 /translation="MTKPSLEMSAAVLGVLKAGAAFVPIDPDYPDQRIEYILQDSGAKL LLKQEGISVPDSFTGDVILLDGSRTILSLPLDENDEGNPETAVTAENLAYMIYTSGTTG QPKGVMVEHHALVNLCFWHHDAFSMTAEDRSAKYAGFGFDASIWEMFPTWTIGAELHVI DEAIRLDIVRLNDYFETNGVTITFLPTQLAEQFMELENTSLRVLLTGGDKLKRAVKKPY TLVNNYGPTENTVVATSAEIHPEEGSLSIGRAIANTRVYILGEGNQVQPEGVAGELCVA GRGLARGYLNREDETAKRFVADPFVPGERMYRTGDLVKWVNGGIEYIGRIDQQVKVRGY RIELSEIEVQLAQLSEVQDAAVTAVKDKGGNTAIAAYVTPETADIEALKSALKETLPDY MIPAFWVTLSELPVTANGKVDRKALPEPDIEAGSGEYKAPTTDMEELLAGIWQDVLGMS EVGVTDNFFSLGGDSIKGIQMASRLNQHGWKLEMKDLFQHPTIEELTQYVERAEGKQAD QGPVEGEVILTPIQRWFFEKNFTNKHHWNQSVMLHAAKGFDPERVEKTLQALIEHHDAL RMVYREGQEDVIQYNRGLEAASAQLEVIQIEGQAADYEDRIEREAERLQSSIDLQEGGL LKAGLFQAEDGDHLLLAIHHLVVDGVSWRILLEDFAAVYTQLEQGNEPVFPQKTHSFAE YAERLQDFANSKAFLKEKEYWRQLEEQAVAAKLPKDRESGDQRMKHTKTIEFSLTAEET EQLTTKVHEAYHTEMNDILLTAFGLAMKEWTGQDRVNVHLEGHGREEIIEDLTISRTVG WFTSMYPMVLDMKHADDLGYQLKQMKEDIRHVPNKGVGYGILRYLTAPEHKEDVAFSIQ PDVSFNYLGQFDEMSDAGLFTRSELPSGQSLSPETEKPNALDVVGYIENGKLTMSLAYH SLEFHEKTVQTFSDSFKAHLLRIIEHCLSQDGTELTPSDLGDDDLTLDELDKLMEIF" aSDomain 6..1016 /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg23_1_AMP-binding.1" /evalue="3.60E-86" /label="ctg23_1_AMP-binding.1" /locus_tag="ctg23_1" /protein_end="338" /protein_start="1" /score="281.1" /specificity="substrate consensus: Leu" /tool="antismash" /translation="TKPSLEMSAAVLGVLKAGAAFVPIDPDYPDQRIEYILQDSGAKLL LKQEGISVPDSFTGDVILLDGSRTILSLPLDENDEGNPETAVTAENLAYMIYTSGTTGQ PKGVMVEHHALVNLCFWHHDAFSMTAEDRSAKYAGFGFDASIWEMFPTWTIGAELHVID EAIRLDIVRLNDYFETNGVTITFLPTQLAEQFMELENTSLRVLLTGGDKLKRAVKKPYT LVNNYGPTENTVVATSAEIHPEEGSLSIGRAIANTRVYILGEGNQVQPEGVAGELCVAG RGLARGYLNREDETAKRFVADPFVPGERMYRTGDLVKWVNGGIEYIGRIDQQVKVR" aSModule 6..2951 /complete /domains="nrpspksdomains_ctg23_1_AMP-binding.1" /domains="nrpspksdomains_ctg23_1_PCP.1" /domains="nrpspksdomains_ctg23_1_Epimerization.1" /domains="nrpspksdomains_ctg23_1_TIGR01720.1" /locus_tags="ctg23_1" /monomer_pairings="Leu -> D-Leu" /starter_module /tool="antismash" /type="nrps" CDS_motif 39..80 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_1_0001" /evalue="9.40E-06" /label="NRPS-A_a2" /locus_tag="ctg23_1" /protein_end="26" /protein_start="12" /score="18.7" /tool="antismash" /translation="LGVLKAGAAFVPID" CDS_motif 282..341 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_1_0002" /evalue="7.20E-11" /label="NRPS-A_a3" /locus_tag="ctg23_1" /protein_end="113" /protein_start="93" /score="33.8" /tool="antismash" /translation="AYMIYTSGTTGQPKGVMVEH" CDS_motif 681..710 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_1_0003" /evalue="5.80E-03" /label="NRPS-A_a5" /locus_tag="ctg23_1" /protein_end="236" /protein_start="226" /score="9.4" /tool="antismash" /translation="NYGPTENTVV" CDS_motif 813..902 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_1_0004" /evalue="4.00E-16" /label="NRPS-A_a6" /locus_tag="ctg23_1" /protein_end="300" /protein_start="270" /score="51.1" /tool="antismash" /translation="PEGVAGELCVAGRGLARGYLNREDETAKRF" CDS_motif 981..1046 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_1_0005" /evalue="2.10E-11" /label="NRPS-A_a8" /locus_tag="ctg23_1" /protein_end="348" /protein_start="326" /score="35.8" /tool="antismash" /translation="YIGRIDQQVKVRGYRIELSEIE" aSDomain 1332..1535 /aSDomain="PCP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg23_1_PCP.1" /evalue="5.90E-28" /label="ctg23_1_PCP.1" /locus_tag="ctg23_1" /protein_end="511" /protein_start="443" /score="88.8" /tool="antismash" /translation="EELLAGIWQDVLGMSEVGVTDNFFSLGGDSIKGIQMASRLNQHGW KLEMKDLFQHPTIEELTQYVERA" aSDomain 1566..2474 /aSDomain="Epimerization" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg23_1_Epimerization.1" /evalue="8.90E-178" /label="ctg23_1_Epimerization.1" /locus_tag="ctg23_1" /protein_end="824" /protein_start="521" /score="584.4" /tool="antismash" /translation="EGEVILTPIQRWFFEKNFTNKHHWNQSVMLHAAKGFDPERVEKTL QALIEHHDALRMVYREGQEDVIQYNRGLEAASAQLEVIQIEGQAADYEDRIEREAERLQ SSIDLQEGGLLKAGLFQAEDGDHLLLAIHHLVVDGVSWRILLEDFAAVYTQLEQGNEPV FPQKTHSFAEYAERLQDFANSKAFLKEKEYWRQLEEQAVAAKLPKDRESGDQRMKHTKT IEFSLTAEETEQLTTKVHEAYHTEMNDILLTAFGLAMKEWTGQDRVNVHLEGHGREEII EDLTISRTVGWFTSMYPMVLDM" CDS_motif 1581..1610 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_1_0006" /evalue="6.70E-05" /label="NRPS-E1" /locus_tag="ctg23_1" /protein_end="536" /protein_start="526" /score="15.6" /tool="antismash" /translation="LTPIQRWFFE" CDS_motif 1671..1745 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_1_0007" /evalue="3.80E-06" /label="C2_LCL_024-062" /locus_tag="ctg23_1" /protein_end="581" /protein_start="556" /score="19.3" /tool="antismash" /translation="FDPERVEKTLQALIEHHDALRMVYR" CDS_motif 1947..2012 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_1_0008" /evalue="3.50E-12" /label="NRPS-E2" /locus_tag="ctg23_1" /protein_end="670" /protein_start="648" /score="38.4" /tool="antismash" /translation="LLLAIHHLVVDGVSWRILLEDF" CDS_motif 2421..2468 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_1_0009" /evalue="1.90E-08" /label="NRPS-E5" /locus_tag="ctg23_1" /protein_end="822" /protein_start="806" /score="26.3" /tool="antismash" /translation="ISRTVGWFTSMYPMVL" aSDomain 2490..2951 /aSDomain="TIGR01720" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg23_1_TIGR01720.1" /evalue="1.30E-55" /label="ctg23_1_TIGR01720.1" /locus_tag="ctg23_1" /protein_end="983" /protein_start="829" /score="179.3" /tool="antismash" /translation="LGYQLKQMKEDIRHVPNKGVGYGILRYLTAPEHKEDVAFSIQPDV SFNYLGQFDEMSDAGLFTRSELPSGQSLSPETEKPNALDVVGYIENGKLTMSLAYHSLE FHEKTVQTFSDSFKAHLLRIIEHCLSQDGTELTPSDLGDDDLTLDELDKL" CDS_motif 2514..2573 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_1_0010" /evalue="1.80E-09" /label="NRPS-E6" /locus_tag="ctg23_1" /protein_end="857" /protein_start="837" /score="29.7" /tool="antismash" /translation="KEDIRHVPNKGVGYGILRYL" aSDomain 2979..3065 /aSDomain="NRPS-COM_Nterm" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg23_2_NRPS-COM_Nterm.1" /evalue="5.10E-14" /label="ctg23_2_NRPS-COM_Nterm.1" /locus_tag="ctg23_2" /protein_end="29" /protein_start="0" /score="43.1" /tool="antismash" /translation="MSKKSIQKVYALTPMQEGMLYHAMLDPHS" CDS 2979..13727 /NRPS_PKS="Domain: NRPS-COM_Nterm (0-29). E-value: 5.1e-14. Score: 43.1. Matches aSDomain: nrpspksdomains_ctg23_2_NRPS-COM_Nterm.1" /NRPS_PKS="Domain: Condensation_DCL (6-305). E-value: 4.6e-114. Score: 372.4. Matches aSDomain: nrpspksdomains_ctg23_2_Condensation_DCL.1" /NRPS_PKS="Domain: AMP-binding (470-863). E-value: 4.3e-111. Score: 363.2. Matches aSDomain: nrpspksdomains_ctg23_2_AMP-binding.1" /NRPS_PKS="Domain: PCP (969-1037). E-value: 1.5e-21. Score: 68.3. Matches aSDomain: nrpspksdomains_ctg23_2_PCP.1" /NRPS_PKS="Domain: Condensation_LCL (1053-1337). E-value: 1.6e-102. Score: 334.4. Matches aSDomain: nrpspksdomains_ctg23_2_Condensation_LCL.1" /NRPS_PKS="Domain: AMP-binding (1500-1903). E-value: 2e-115. Score: 377.5. Matches aSDomain: nrpspksdomains_ctg23_2_AMP-binding.2" /NRPS_PKS="Domain: PCP (2009-2077). E-value: 3.1e-25. Score: 80.1. Matches aSDomain: nrpspksdomains_ctg23_2_PCP.2" /NRPS_PKS="Domain: Condensation_LCL (2094-2380). E-value: 3.1e-105. Score: 343.3. Matches aSDomain: nrpspksdomains_ctg23_2_Condensation_LCL.2" /NRPS_PKS="Domain: AMP-binding (2545-2933). E-value: 7.1e-105. Score: 342.7. Matches aSDomain: nrpspksdomains_ctg23_2_AMP-binding.3" /NRPS_PKS="Domain: PCP (3038-3106). E-value: 3.2e-27. Score: 86.4. Matches aSDomain: nrpspksdomains_ctg23_2_PCP.3" /NRPS_PKS="Domain: Epimerization (3116-3419). E-value: 2e-161. Score: 530.3. Matches aSDomain: nrpspksdomains_ctg23_2_Epimerization.1" /NRPS_PKS="Domain: TIGR01720 (3423-3572). E-value: 3.6e-53. Score: 171.4. Matches aSDomain: nrpspksdomains_ctg23_2_TIGR01720.1" /gene_functions="biosynthetic (rule-based-clusters) NRPS: Condensation" /gene_functions="biosynthetic (rule-based-clusters) NRPS: AMP-binding" /gene_functions="biosynthetic-additional (rule-based-clusters) PP-binding" /gene_functions="biosynthetic-additional (smcogs) SMCOG1002:AMP-dependent synthetase and ligase (Score: 343.7; E-value: 2.4e-104)" /gene_kind="biosynthetic" /locus_tag="ctg23_2" /sec_met_domain="AMP-binding (E-value: 4e-124, bitscore: 408.2, seeds: 400, tool: rule-based-clusters)" /sec_met_domain="Condensation (E-value: 5.8e-97, bitscore: 318.3, seeds: 42, tool: rule-based-clusters)" /sec_met_domain="PP-binding (E-value: 1e-16, bitscore: 55.2, seeds: 164, tool: rule-based-clusters)" /transl_table=11 /translation="MSKKSIQKVYALTPMQEGMLYHAMLDPHSSSYFTQLELGIHGAFD LEIFEKSVNELIRSYDILRTVFVHQQLQKPRQVVLAERKTKVHYEDISHADENRQKEHI ERYKQDVQRQGFNLAKDILFKVAVFRLDADQLYLVWSNHHIMMDGWSMGVLMKSLFQNY EALRAGRTPANGQGKPYSDYIKWLGKQDNEEAESYWSERLAGFEQPSVLPGRLPVKKDE YVNKEYSFTWDETLVARIQKTANLHQVTGPNLFQAVWGIVLSKYNFTDDVIFGTVVSGR PSEINGIETMAGLFINTIPVRVKVERDAAFADIFTAVQQHAVEAERYDYVPLYEIQKRS ALDGNLLNHLVAFENYPLDQELENGSMEDRLGFSIKVESAFEQTSFDFNLIVYPGKTWT VKIKYNGAAFDSAFIERTAEHLTRMMEAAVDQPAAFVREYGLVGDEEQRQIVEVFNSTK AELPEGMAVHQVFEEQAKRTPASTAVVYEGTELTYRELNAAANRLARKLVEQGLQKGET AAIMNDRSVETVVGMLAVLKAGAAYVPLDPALPGDRLRFMAEDSSVRMVLTGNSYTGQA HQLQVPVLTLDIGIEDGEADNLNLPSAPSDLAYIMYTSGSTGKPKGVMIEHKSILRLVK NAGYVPVTEEDRMAQTGAVSFDAGTFEVFGALLNGAALYPVKKETLLDAKQFAAFLREQ SITTMWLTSPLFNQLAAKDAGMFGTLRHLIIGGDALVPHIVSKVKQASPSLSLWNGYGP TENTTFSTSFLIDREYGGSIPIGKPIGNSTAYILDEQQCLQPIGAPGELCVGGIGVARG YVNLPELTEKQFLEDPFRPGERIYRTGDLARWLPDGNIEFLGRIDNQVKVRGFRIELGE IETKLNMAEHVTEAVVIIRKNKADENEICAYFTADREVAVSELRKTLSQSLPDYMVPAH LIQMDSLPLTPNGKINKKELPAPQSEAVQPEYAAPETESEKKLAEIWEGILGVRAGVTD NFFMIGGHSLKAMMMTAKIQEHFHKEVPIKVLFEKPTIQELALYLEENESKEEQTFEPI RQASYQQHYPVSPAQRRMYILNQLGQANTSYNVPAVLLLEGEVDKARLENAIQQLINRH EILRTSFDMIDGEVVQTVHKNISFQLEAAKGREEDAEEIIKAFVQPFELNRAPLVRSKL VQLEEKRHLLLIDMHHIITDGSSTGILIGDLAKIYQGADLELPQIHYKDYAVWHKEQTN YQKDEEYWLDVFKGELPILDLPADFERPAERSFAGERVMFGLDKQITAQIKSLMAETDT TMYMFLLAAFNVLLSKYASQDDIIVGSPTAGRTHPDLQGVPGMFVNTVALRTAPAGDKT FAQFLEEVKTASLQAFEHQSYPLEELIEKLPLTRDTSRSPLFSVMFNMQNMEIPSLRLG DLKISSYSMLHHVAKFDLSLEAVEREEDIGLSFDYATALFKDETIRRWSRHFVNIIKAA AANPNVRLSDVDLLSSAETAALLEERHMTQITEATFAALFEKQAQQTPDHPAVKAGGNL LTYRELDEQANQLAHHLRAQGAGNEDIVAIVMDRSAEVMVSILGVMKAGAAFLPIDPDT PEERIRYSLEDSGAKIAVVNERNMTAIGQYEGTIVSLDDGKWRNESKERPSSISGSRNL AYVIYTSGTTGKPKGVQIEHRNLTNYVSWFSEEASLTENDKTVLLSSYAFDLGYTSMFP VLLGGGELHIVQKETYTAPDEIAHYIKEHGITYIKLTPSLFHTIVNTASFAKDANFESL RLIVLGGEKIIPTDVLAFRKMYGHTEFINHYGPTEATIGAIAGRVDLSEPDAFAKRPTI GRPIANAGALVLNEALKLVPPGASGQLYITGQGLARGYLNRPQLTAERFVENPYSPGSL MYKTGDVVRRLSDGTLAFIGRADDQVKIRGYRIEPKEIETVMLSLSGIQEAVVLAVSEG GLQELCAYYTSDQDIEKAELRYQLSLTLPSHMIPAFFVQVDAIPLTANGKTDRNALPKP NAAQSGGKALAAPETALEESLCRIWQKTLGIEAIGIDDNFFDLGGHSLKGMMLIANIQA ELEKSVPLKALFEQPTVRQLAAYMEASAVSGGHQVLKPADKQAIYPLSSAQKRMYVLNQ LDRQTISYNMPSVLLMEGELDISRLRDSLNQLVNRHESLRTSFMEANGEPVQRIIEKAE VDLHLFEAKEDEADQKIKEFIRPFDLNDAPLIRAALLRIEAKKHLLLLDMHHIIADGVS RGIFVKELALLYKGEQLPEPALHYKDFAVWQNEAEQKERMKEHEAYWMSVLSGELPELD LPLDYARPPVQSFKGDTIRFRTGSETAKAVEKLLAETGTTLHMVLHAVFHVFLSKISGQ RDIVIGSVTAGRTNADVQDMPGMFVNTLALRMEAKEQQTFAELLEQAKQTNLSALEHQE YPFEDLVNQLDLPRDMSRNPLFNVMVTTENPDKEQLTLQNLSISPYEAHQGTSKFDLTL GGFTDENGIGLQLEYATDLFAKETVEKWSEYVLRLLKAVADNPNQPLSSLSLVTETEKQ ALLEAWKGKALPVPTDKTVHQLFEETVQRHKDRPAVTYNGQSWTYGELNAKANRLARIL MDCGISPDDRVGVLTKPSLEMSAAVLGVLKAGAAFVPIDPDYPDQRIEYILQDSGAKLL LKQEGISVPDSFSGDVILLDGSRTILSLPLDENDEGNPETAVTAENLAYMIYTSGTTGQ PKGVMVEHHALVNLCFWHHDAFSMTAEDRSAKYAGFGFDASIWEMFPTWTIGAELHVID EAIRLDIVRLNDYFETNGVTITFLPTQLAEQFMELENTSLRVLLTGGDKLKRAVKKPYT LVNNYGPTENTVVATSAEIHPEEGSLSIGRAIANTRVYILGEGNQVQPEGVAGELCVAG RGLARGYLNREDETAKRFVADPFVPGERMYRTGDLVKWTGGGIEYIGRIDQQVKVRGYR IELSEIEVQLAQLSEVQDAAVTAVKDKGGNTAIAAYVTPETADIEALKSALKETLPDYM IPAFWVKLNELPVTANGKVDRKALPEPDIEAGSGEYKAPTTDMEELLAGIWQDVLGMAE VGVTDNFFSLGGDSIKGIQMASRLNQHGWKLEMKDLFQHPTIEELTQYVERAEGKQADQ GPVEGEVILTPIQRWFFEKNFTNKHHWNQSVMLHAKKGFDPERVEKTLQALIEHHDALR MVFREENGDIVQAYQPIGESEVSFEIVDLYGSDEEMLRSQIKILANKLQSSLDLQNGPL LKAEQYRTEAGDHLLIAVHHLVVDGVSWRILLEDFASGYMQAEKEESLVFPQKTNSFKD WAEELAAFSQSAHLLQQAEYWSQIAAEKVSPLPKDCETEQRIVKDTSSVLCELTEEDTK HLLTDVHQPYGTEINDILLSALGLTMKEWTKGAKIGINLEGHGREDIIPNVNISRTVGW FTAQYPVVLDISDADASAVIKTVKENLRRIPDKGVGYGILRYFTETAETKGFTPEISFN YLGQFDSEVKTDFFEPSAFDMGRQVSGESEALYALSFSGMIRNGRFVLSCSYNEKEFER VTIEERMERFKENLLMLIRHCTEKEDKEFTPSDFSAEDLEMDEMGDIFDMLEENLK" aSDomain 2997..3893 /aSDomain="Condensation" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg23_2_Condensation_DCL.1" /domain_subtypes="Condensation_DCL" /evalue="4.60E-114" /label="ctg23_2_Condensation_DCL.1" /locus_tag="ctg23_2" /protein_end="305" /protein_start="6" /score="372.4" /tool="antismash" /translation="QKVYALTPMQEGMLYHAMLDPHSSSYFTQLELGIHGAFDLEIFEK SVNELIRSYDILRTVFVHQQLQKPRQVVLAERKTKVHYEDISHADENRQKEHIERYKQD VQRQGFNLAKDILFKVAVFRLDADQLYLVWSNHHIMMDGWSMGVLMKSLFQNYEALRAG RTPANGQGKPYSDYIKWLGKQDNEEAESYWSERLAGFEQPSVLPGRLPVKKDEYVNKEY SFTWDETLVARIQKTANLHQVTGPNLFQAVWGIVLSKYNFTDDVIFGTVVSGRPSEING IETMAGLFINTIPVRVKV" aSModule 2997..6089 /complete /domains="nrpspksdomains_ctg23_2_Condensation_DCL.1" /domains="nrpspksdomains_ctg23_2_AMP-binding.1" /domains="nrpspksdomains_ctg23_2_PCP.1" /locus_tags="ctg23_2" /monomer_pairings="Val -> Val" /tool="antismash" /type="nrps" CDS_motif 3006..3044 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0001" /evalue="9.80E-05" /label="C1_dual_004-017" /locus_tag="ctg23_2" /protein_end="22" /protein_start="9" /score="15.1" /tool="antismash" /translation="YALTPMQEGMLYH" CDS_motif 3069..3185 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0002" /evalue="1.10E-13" /label="C2_DCL_024-062" /locus_tag="ctg23_2" /protein_end="69" /protein_start="30" /score="43.4" /tool="antismash" /translation="SYFTQLELGIHGAFDLEIFEKSVNELIRSYDILRTVFVH" CDS_motif 3402..3467 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0003" /evalue="4.50E-11" /label="C3_DCL_135-156" /locus_tag="ctg23_2" /protein_end="163" /protein_start="141" /score="35.1" /tool="antismash" /translation="NHHIMMDGWSMGVLMKSLFQNY" CDS_motif 3513..3551 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0004" /evalue="5.50E-03" /label="C4_DCL_171-183" /locus_tag="ctg23_2" /protein_end="191" /protein_start="178" /score="9.6" /tool="antismash" /translation="PYSDYIKWLGKQD" CDS_motif 3789..3884 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0005" /evalue="9.20E-19" /label="C5_DCL_263-294" /locus_tag="ctg23_2" /protein_end="302" /protein_start="270" /score="59.9" /tool="antismash" /translation="DVIFGTVVSGRPSEINGIETMAGLFINTIPVR" CDS_motif 3933..4049 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0006" /evalue="6.70E-17" /label="C67_DCL_14fromHMM" /locus_tag="ctg23_2" /protein_end="357" /protein_start="318" /score="53.9" /tool="antismash" /translation="QQHAVEAERYDYVPLYEIQKRSALDGNLLNHLVAFENYP" aSDomain 4389..5567 /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg23_2_AMP-binding.1" /evalue="4.30E-111" /label="ctg23_2_AMP-binding.1" /locus_tag="ctg23_2" /protein_end="863" /protein_start="470" /score="363.2" /specificity="substrate consensus: Val" /tool="antismash" /translation="FEEQAKRTPASTAVVYEGTELTYRELNAAANRLARKLVEQGLQKG ETAAIMNDRSVETVVGMLAVLKAGAAYVPLDPALPGDRLRFMAEDSSVRMVLTGNSYTG QAHQLQVPVLTLDIGIEDGEADNLNLPSAPSDLAYIMYTSGSTGKPKGVMIEHKSILRL VKNAGYVPVTEEDRMAQTGAVSFDAGTFEVFGALLNGAALYPVKKETLLDAKQFAAFLR EQSITTMWLTSPLFNQLAAKDAGMFGTLRHLIIGGDALVPHIVSKVKQASPSLSLWNGY GPTENTTFSTSFLIDREYGGSIPIGKPIGNSTAYILDEQQCLQPIGAPGELCVGGIGVA RGYVNLPELTEKQFLEDPFRPGERIYRTGDLARWLPDGNIEFLGRIDNQVKVR" CDS_motif 4575..4616 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0007" /evalue="6.40E-06" /label="NRPS-A_a2" /locus_tag="ctg23_2" /protein_end="546" /protein_start="532" /score="19.2" /tool="antismash" /translation="LAVLKAGAAYVPLD" CDS_motif 4800..4859 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0008" /evalue="7.60E-11" /label="NRPS-A_a3" /locus_tag="ctg23_2" /protein_end="627" /protein_start="607" /score="33.8" /tool="antismash" /translation="AYIMYTSGSTGKPKGVMIEH" CDS_motif 5229..5252 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0009" /evalue="1.30E+00" /label="NRPS-A_a5" /locus_tag="ctg23_2" /protein_end="758" /protein_start="750" /score="2.8" /tool="antismash" /translation="YGPTENTT" CDS_motif 5361..5450 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0010" /evalue="1.10E-14" /label="NRPS-A_a6" /locus_tag="ctg23_2" /protein_end="824" /protein_start="794" /score="46.5" /tool="antismash" /translation="PIGAPGELCVGGIGVARGYVNLPELTEKQF" CDS_motif 5532..5597 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0011" /evalue="5.80E-12" /label="NRPS-A_a8" /locus_tag="ctg23_2" /protein_end="873" /protein_start="851" /score="37.5" /tool="antismash" /translation="FLGRIDNQVKVRGFRIELGEIE" aSDomain 5886..6089 /aSDomain="PCP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg23_2_PCP.1" /evalue="1.50E-21" /label="ctg23_2_PCP.1" /locus_tag="ctg23_2" /protein_end="1037" /protein_start="969" /score="68.3" /tool="antismash" /translation="EKKLAEIWEGILGVRAGVTDNFFMIGGHSLKAMMMTAKIQEHFHK EVPIKVLFEKPTIQELALYLEEN" aSDomain 6138..6989 /aSDomain="Condensation" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg23_2_Condensation_LCL.1" /domain_subtypes="Condensation_LCL" /evalue="1.60E-102" /label="ctg23_2_Condensation_LCL.1" /locus_tag="ctg23_2" /protein_end="1337" /protein_start="1053" /score="334.4" /tool="antismash" /translation="QQHYPVSPAQRRMYILNQLGQANTSYNVPAVLLLEGEVDKARLEN AIQQLINRHEILRTSFDMIDGEVVQTVHKNISFQLEAAKGREEDAEEIIKAFVQPFELN RAPLVRSKLVQLEEKRHLLLIDMHHIITDGSSTGILIGDLAKIYQGADLELPQIHYKDY AVWHKEQTNYQKDEEYWLDVFKGELPILDLPADFERPAERSFAGERVMFGLDKQITAQI KSLMAETDTTMYMFLLAAFNVLLSKYASQDDIIVGSPTAGRTHPDLQGVPGMFVNTVAL RTA" aSModule 6138..9209 /complete /domains="nrpspksdomains_ctg23_2_Condensation_LCL.1" /domains="nrpspksdomains_ctg23_2_AMP-binding.2" /domains="nrpspksdomains_ctg23_2_PCP.2" /locus_tags="ctg23_2" /monomer_pairings="Asp -> Asp" /tool="antismash" /type="nrps" CDS_motif 6207..6320 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0012" /evalue="6.90E-17" /label="C2_LCL_024-062" /locus_tag="ctg23_2" /protein_end="1114" /protein_start="1076" /score="53.8" /tool="antismash" /translation="TSYNVPAVLLLEGEVDKARLENAIQQLINRHEILRTSF" CDS_motif 6516..6581 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0013" /evalue="3.40E-08" /label="C3_LCL_132-143" /locus_tag="ctg23_2" /protein_end="1201" /protein_start="1179" /score="26.0" /tool="antismash" /translation="MHHIITDGSSTGILIGDLAKIY" CDS_motif 6612..6647 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0014" /evalue="4.90E-03" /label="C4_LCL_164-176" /locus_tag="ctg23_2" /protein_end="1223" /protein_start="1211" /score="9.7" /tool="antismash" /translation="HYKDYAVWHKEQ" CDS_motif 6894..6983 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0015" /evalue="3.70E-15" /label="C5_LCL_267-296" /locus_tag="ctg23_2" /protein_end="1335" /protein_start="1305" /score="48.2" /tool="antismash" /translation="DIIVGSPTAGRTHPDLQGVPGMFVNTVALR" CDS_motif 7038..7151 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0016" /evalue="9.80E-16" /label="C67_LCL_14fromHMM" /locus_tag="ctg23_2" /protein_end="1391" /protein_start="1353" /score="50.1" /tool="antismash" /translation="ASLQAFEHQSYPLEELIEKLPLTRDTSRSPLFSVMFNM" aSDomain 7479..8687 /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg23_2_AMP-binding.2" /evalue="2.00E-115" /label="ctg23_2_AMP-binding.2" /locus_tag="ctg23_2" /protein_end="1903" /protein_start="1500" /score="377.5" /specificity="substrate consensus: Asp" /tool="antismash" /translation="FEKQAQQTPDHPAVKAGGNLLTYRELDEQANQLAHHLRAQGAGNE DIVAIVMDRSAEVMVSILGVMKAGAAFLPIDPDTPEERIRYSLEDSGAKIAVVNERNMT AIGQYEGTIVSLDDGKWRNESKERPSSISGSRNLAYVIYTSGTTGKPKGVQIEHRNLTN YVSWFSEEASLTENDKTVLLSSYAFDLGYTSMFPVLLGGGELHIVQKETYTAPDEIAHY IKEHGITYIKLTPSLFHTIVNTASFAKDANFESLRLIVLGGEKIIPTDVLAFRKMYGHT EFINHYGPTEATIGAIAGRVDLSEPDAFAKRPTIGRPIANAGALVLNEALKLVPPGASG QLYITGQGLARGYLNRPQLTAERFVENPYSPGSLMYKTGDVVRRLSDGTLAFIGRADDQ VKIR" CDS_motif 7665..7706 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0017" /evalue="1.40E-04" /label="NRPS-A_a2" /locus_tag="ctg23_2" /protein_end="1576" /protein_start="1562" /score="15.2" /tool="antismash" /translation="LGVMKAGAAFLPID" CDS_motif 7893..7952 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0018" /evalue="4.00E-10" /label="NRPS-A_a3" /locus_tag="ctg23_2" /protein_end="1658" /protein_start="1638" /score="31.6" /tool="antismash" /translation="AYVIYTSGTTGKPKGVQIEH" CDS_motif 8337..8360 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0019" /evalue="1.30E-01" /label="NRPS-A_a5" /locus_tag="ctg23_2" /protein_end="1794" /protein_start="1786" /score="5.6" /tool="antismash" /translation="YGPTEATI" CDS_motif 8481..8570 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0020" /evalue="1.70E-15" /label="NRPS-A_a6" /locus_tag="ctg23_2" /protein_end="1864" /protein_start="1834" /score="49.0" /tool="antismash" /translation="PPGASGQLYITGQGLARGYLNRPQLTAERF" CDS_motif 8652..8717 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0021" /evalue="1.40E-11" /label="NRPS-A_a8" /locus_tag="ctg23_2" /protein_end="1913" /protein_start="1891" /score="36.3" /tool="antismash" /translation="FIGRADDQVKIRGYRIEPKEIE" aSDomain 9006..9209 /aSDomain="PCP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg23_2_PCP.2" /evalue="3.10E-25" /label="ctg23_2_PCP.2" /locus_tag="ctg23_2" /protein_end="2077" /protein_start="2009" /score="80.1" /tool="antismash" /translation="EESLCRIWQKTLGIEAIGIDDNFFDLGGHSLKGMMLIANIQAELE KSVPLKALFEQPTVRQLAAYMEA" aSDomain 9261..10118 /aSDomain="Condensation" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg23_2_Condensation_LCL.2" /domain_subtypes="Condensation_LCL" /evalue="3.10E-105" /label="ctg23_2_Condensation_LCL.2" /locus_tag="ctg23_2" /protein_end="2380" /protein_start="2094" /score="343.3" /tool="antismash" /translation="IYPLSSAQKRMYVLNQLDRQTISYNMPSVLLMEGELDISRLRDSL NQLVNRHESLRTSFMEANGEPVQRIIEKAEVDLHLFEAKEDEADQKIKEFIRPFDLNDA PLIRAALLRIEAKKHLLLLDMHHIIADGVSRGIFVKELALLYKGEQLPEPALHYKDFAV WQNEAEQKERMKEHEAYWMSVLSGELPELDLPLDYARPPVQSFKGDTIRFRTGSETAKA VEKLLAETGTTLHMVLHAVFHVFLSKISGQRDIVIGSVTAGRTNADVQDMPGMFVNTLA LRMEA" aSModule 9261..13694 /complete /domains="nrpspksdomains_ctg23_2_Condensation_LCL.2" /domains="nrpspksdomains_ctg23_2_AMP-binding.3" /domains="nrpspksdomains_ctg23_2_PCP.3" /domains="nrpspksdomains_ctg23_2_Epimerization.1" /domains="nrpspksdomains_ctg23_2_TIGR01720.1" /locus_tags="ctg23_2" /monomer_pairings="Leu -> D-Leu" /tool="antismash" /type="nrps" CDS_motif 9327..9437 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0022" /evalue="2.50E-16" /label="C2_LCL_024-062" /locus_tag="ctg23_2" /protein_end="2153" /protein_start="2116" /score="52.0" /tool="antismash" /translation="SYNMPSVLLMEGELDISRLRDSLNQLVNRHESLRTSF" CDS_motif 9633..9698 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0023" /evalue="7.10E-09" /label="C3_LCL_132-143" /locus_tag="ctg23_2" /protein_end="2240" /protein_start="2218" /score="28.2" /tool="antismash" /translation="MHHIIADGVSRGIFVKELALLY" CDS_motif 9729..9761 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0024" /evalue="4.90E-04" /label="C4_LCL_164-176" /locus_tag="ctg23_2" /protein_end="2261" /protein_start="2250" /score="12.8" /tool="antismash" /translation="HYKDFAVWQNE" CDS_motif 10020..10109 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0025" /evalue="4.30E-14" /label="C5_LCL_267-296" /locus_tag="ctg23_2" /protein_end="2377" /protein_start="2347" /score="44.8" /tool="antismash" /translation="DIVIGSVTAGRTNADVQDMPGMFVNTLALR" CDS_motif 10158..10271 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0026" /evalue="2.30E-17" /label="C67_LCL_14fromHMM" /locus_tag="ctg23_2" /protein_end="2431" /protein_start="2393" /score="55.3" /tool="antismash" /translation="KQTNLSALEHQEYPFEDLVNQLDLPRDMSRNPLFNVMV" aSDomain 10614..11777 /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg23_2_AMP-binding.3" /evalue="7.10E-105" /label="ctg23_2_AMP-binding.3" /locus_tag="ctg23_2" /protein_end="2933" /protein_start="2545" /score="342.7" /specificity="substrate consensus: Leu" /tool="antismash" /translation="FEETVQRHKDRPAVTYNGQSWTYGELNAKANRLARILMDCGISPD DRVGVLTKPSLEMSAAVLGVLKAGAAFVPIDPDYPDQRIEYILQDSGAKLLLKQEGISV PDSFSGDVILLDGSRTILSLPLDENDEGNPETAVTAENLAYMIYTSGTTGQPKGVMVEH HALVNLCFWHHDAFSMTAEDRSAKYAGFGFDASIWEMFPTWTIGAELHVIDEAIRLDIV RLNDYFETNGVTITFLPTQLAEQFMELENTSLRVLLTGGDKLKRAVKKPYTLVNNYGPT ENTVVATSAEIHPEEGSLSIGRAIANTRVYILGEGNQVQPEGVAGELCVAGRGLARGYL NREDETAKRFVADPFVPGERMYRTGDLVKWTGGGIEYIGRIDQQVKVR" CDS_motif 10800..10841 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0027" /evalue="4.10E-05" /label="NRPS-A_a2" /locus_tag="ctg23_2" /protein_end="2621" /protein_start="2607" /score="16.8" /tool="antismash" /translation="LGVLKAGAAFVPID" CDS_motif 11043..11102 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0028" /evalue="3.10E-10" /label="NRPS-A_a3" /locus_tag="ctg23_2" /protein_end="2708" /protein_start="2688" /score="31.9" /tool="antismash" /translation="AYMIYTSGTTGQPKGVMVEH" CDS_motif 11442..11471 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0029" /evalue="2.70E-02" /label="NRPS-A_a5" /locus_tag="ctg23_2" /protein_end="2831" /protein_start="2821" /score="7.5" /tool="antismash" /translation="NYGPTENTVV" CDS_motif 11574..11663 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0030" /evalue="1.70E-15" /label="NRPS-A_a6" /locus_tag="ctg23_2" /protein_end="2895" /protein_start="2865" /score="49.1" /tool="antismash" /translation="PEGVAGELCVAGRGLARGYLNREDETAKRF" CDS_motif 11742..11807 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0031" /evalue="8.60E-11" /label="NRPS-A_a8" /locus_tag="ctg23_2" /protein_end="2943" /protein_start="2921" /score="33.9" /tool="antismash" /translation="YIGRIDQQVKVRGYRIELSEIE" aSDomain 12093..12296 /aSDomain="PCP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg23_2_PCP.3" /evalue="3.20E-27" /label="ctg23_2_PCP.3" /locus_tag="ctg23_2" /protein_end="3106" /protein_start="3038" /score="86.4" /tool="antismash" /translation="EELLAGIWQDVLGMAEVGVTDNFFSLGGDSIKGIQMASRLNQHGW KLEMKDLFQHPTIEELTQYVERA" aSDomain 12327..13235 /aSDomain="Epimerization" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg23_2_Epimerization.1" /evalue="2.00E-161" /label="ctg23_2_Epimerization.1" /locus_tag="ctg23_2" /protein_end="3419" /protein_start="3116" /score="530.3" /tool="antismash" /translation="EGEVILTPIQRWFFEKNFTNKHHWNQSVMLHAKKGFDPERVEKTL QALIEHHDALRMVFREENGDIVQAYQPIGESEVSFEIVDLYGSDEEMLRSQIKILANKL QSSLDLQNGPLLKAEQYRTEAGDHLLIAVHHLVVDGVSWRILLEDFASGYMQAEKEESL VFPQKTNSFKDWAEELAAFSQSAHLLQQAEYWSQIAAEKVSPLPKDCETEQRIVKDTSS VLCELTEEDTKHLLTDVHQPYGTEINDILLSALGLTMKEWTKGAKIGINLEGHGREDII PNVNISRTVGWFTAQYPVVLDI" CDS_motif 12342..12371 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0032" /evalue="3.00E-04" /label="NRPS-E1" /locus_tag="ctg23_2" /protein_end="3131" /protein_start="3121" /score="13.7" /tool="antismash" /translation="LTPIQRWFFE" CDS_motif 12432..12506 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0033" /evalue="2.80E-06" /label="C2_LCL_024-062" /locus_tag="ctg23_2" /protein_end="3176" /protein_start="3151" /score="19.8" /tool="antismash" /translation="FDPERVEKTLQALIEHHDALRMVFR" CDS_motif 12711..12776 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0034" /evalue="2.90E-11" /label="NRPS-E2" /locus_tag="ctg23_2" /protein_end="3266" /protein_start="3244" /score="35.5" /tool="antismash" /translation="LLIAVHHLVVDGVSWRILLEDF" CDS_motif 13179..13229 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0035" /evalue="1.10E-07" /label="NRPS-E5" /locus_tag="ctg23_2" /protein_end="3417" /protein_start="3400" /score="23.9" /tool="antismash" /translation="NISRTVGWFTAQYPVVL" aSDomain 13248..13694 /aSDomain="TIGR01720" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg23_2_TIGR01720.1" /evalue="3.60E-53" /label="ctg23_2_TIGR01720.1" /locus_tag="ctg23_2" /protein_end="3572" /protein_start="3423" /score="171.4" /tool="antismash" /translation="ASAVIKTVKENLRRIPDKGVGYGILRYFTETAETKGFTPEISFNY LGQFDSEVKTDFFEPSAFDMGRQVSGESEALYALSFSGMIRNGRFVLSCSYNEKEFERV TIEERMERFKENLLMLIRHCTEKEDKEFTPSDFSAEDLEMDEMGD" CDS_motif 13269..13328 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_2_0036" /evalue="6.60E-11" /label="NRPS-E6" /locus_tag="ctg23_2" /protein_end="3450" /protein_start="3430" /score="34.3" /tool="antismash" /translation="VKENLRRIPDKGVGYGILRY" aSDomain 13764..13859 /aSDomain="NRPS-COM_Nterm" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg23_3_NRPS-COM_Nterm.1" /evalue="1.40E-16" /label="ctg23_3_NRPS-COM_Nterm.1" /locus_tag="ctg23_3" /protein_end="32" /protein_start="0" /score="51.3" /tool="antismash" /translation="MSQFSKDQVQDMYYLSPMQEGMLFHAILNPGQ" CDS 13764..17591 /NRPS_PKS="Domain: NRPS-COM_Nterm (0-32). E-value: 1.4e-16. Score: 51.3. Matches aSDomain: nrpspksdomains_ctg23_3_NRPS-COM_Nterm.1" /NRPS_PKS="Domain: Condensation_DCL (9-308). E-value: 5.8e-119. Score: 388.5. Matches aSDomain: nrpspksdomains_ctg23_3_Condensation_DCL.1" /NRPS_PKS="Domain: AMP-binding (469-867). E-value: 4.8e-110. Score: 359.8. Matches aSDomain: nrpspksdomains_ctg23_3_AMP-binding.1" /NRPS_PKS="Domain: PCP (973-1042). E-value: 1.5e-25. Score: 81.1. Matches aSDomain: nrpspksdomains_ctg23_3_PCP.1" /NRPS_PKS="Domain: Thioesterase (1059-1259). E-value: 5.4e-37. Score: 120.2. Matches aSDomain: nrpspksdomains_ctg23_3_Thioesterase.1" /gene_functions="biosynthetic (rule-based-clusters) NRPS: Condensation" /gene_functions="biosynthetic (rule-based-clusters) NRPS: AMP-binding" /gene_functions="biosynthetic-additional (rule-based-clusters) PP-binding" /gene_functions="biosynthetic-additional (smcogs) SMCOG1127:condensation domain-containing protein (Score: 333.6; E-value: 3.7e-101)" /gene_kind="biosynthetic" /locus_tag="ctg23_3" /sec_met_domain="Condensation (E-value: 2.1e-93, bitscore: 306.6, seeds: 42, tool: rule-based-clusters)" /sec_met_domain="AMP-binding (E-value: 2e-121, bitscore: 399.3, seeds: 400, tool: rule-based-clusters)" /sec_met_domain="PP-binding (E-value: 8.6e-18, bitscore: 58.6, seeds: 164, tool: rule-based-clusters)" /transl_table=11 /translation="MSQFSKDQVQDMYYLSPMQEGMLFHAILNPGQSFYLEQITMKVKG SLNIKCLEESMNVIMDRYDVFRTVFIHEKVKRPVQVVLKKRQFHIEEIDLTHLTGSEQT AKINEYKEQDKIRGFDLTRDIPMRAAIFKKAEESFEWVWSYHHIILDGWCFGIVVQDLF KVYNALREQKPYSLPPVKPYKDYIKWLEKQDKQASLRYWREYLEDFEGQTTFAEQRKKQ KDGYEPKELLFSLPEAETKAFTELAKSQHTTLSTALQAVWSVLISRYQQSGDLAFGTVV SGRPAEIKGVEHMVGLFINVVPRRVKLSEGITFNGLLKQLQEQSLQSEPHQYVPLYDIQ SQADQPKLIDHIIVFENYPLQDAKNEESSENGFDMVDVHVFEKSNYDLNLMASPGDEML IKLAYNENVFDEAFILRLKSQLLTAIQQLIQNPDQPVSTINIVDDREREFLLTGLNPPA QARETKPLTDWFKEAVNVNPDALALTYFGQTLSYRELDEEANRLARRLQKHGAGKGSVV ALYTKRSLELVIGILGVLKAGAAYLPVDPKLPEDRISYMLADSAAACLLTHQEMKEQAA ELPYTGTTLFIDDQTRFEEQASDPATAIDPNDPAYIMYTSGTTGKPKGNITTHANIQGL VKHVDYMAFSEKDTFLSVSNYAFDAFTFDFYASMLNAARLIIADEHTLLDTERLTDLIL QENVNVMFATTALFNLLTDAGEDWMKGLRCILFGGERASVPHVRKALRVMGPGKLINCY GPTEGTVFATAHVVHDIPDSISSLPIGKPISNASVYILNEQSQLQPFGAIGELCISGMG VSKGYVNRADLTKEKFIKNPFKPGETLYRTGDLARWLPDGTIEYAGRIDDQVKIRGHRI ELEEIEKQLQEYPGVKDAVVVADRHESGDASINAYLVNRTQLSAEDVKAHLKKQLPAYM VPQTFTFLDELPLTTNGKVNKRLLPKPDQDQLAEEWIGPRNEMEETIAQIWSEVLGRKQ IGIHDDFFALGGHSLKAMTAASRIKKELGIDLPVKLLFEAPTIAGISAYVKNGGPDGLQ DVTIMNQDQERIIFAFPPVLGYGLMYQNLSSRLPSYKLCAFDFIEEEDRLDRYADLIQK LQPEGPLTLFGYSAGCSLAFEAAKKLEEQGRIVQRIIMVDSYKKQGVSDLDGRTVESDV EALMNVNRDNEALNSEAVKQGLKQKTHAFYSYYVNLISTGQVKADIDLLTSGADFDMPE WLASWEEATTGAYRMKRGFGTHAEMLQGETLDRNAGILLEFLNTQTVTVS" aSDomain 13791..14687 /aSDomain="Condensation" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg23_3_Condensation_DCL.1" /domain_subtypes="Condensation_DCL" /evalue="5.80E-119" /label="ctg23_3_Condensation_DCL.1" /locus_tag="ctg23_3" /protein_end="308" /protein_start="9" /score="388.5" /tool="antismash" /translation="QDMYYLSPMQEGMLFHAILNPGQSFYLEQITMKVKGSLNIKCLEE SMNVIMDRYDVFRTVFIHEKVKRPVQVVLKKRQFHIEEIDLTHLTGSEQTAKINEYKEQ DKIRGFDLTRDIPMRAAIFKKAEESFEWVWSYHHIILDGWCFGIVVQDLFKVYNALREQ KPYSLPPVKPYKDYIKWLEKQDKQASLRYWREYLEDFEGQTTFAEQRKKQKDGYEPKEL LFSLPEAETKAFTELAKSQHTTLSTALQAVWSVLISRYQQSGDLAFGTVVSGRPAEIKG VEHMVGLFINVVPRRVKL" aSModule 13791..17540 /complete /domains="nrpspksdomains_ctg23_3_Condensation_DCL.1" /domains="nrpspksdomains_ctg23_3_AMP-binding.1" /domains="nrpspksdomains_ctg23_3_PCP.1" /domains="nrpspksdomains_ctg23_3_Thioesterase.1" /final_module /locus_tags="ctg23_3" /monomer_pairings="Leu -> Leu" /tool="antismash" /type="nrps" CDS_motif 13800..13841 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_3_0001" /evalue="3.00E-05" /label="C1_DCL_004-017" /locus_tag="ctg23_3" /protein_end="26" /protein_start="12" /score="15.8" /tool="antismash" /translation="YYLSPMQEGMLFHA" CDS_motif 13863..13979 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_3_0002" /evalue="2.50E-12" /label="C2_DCL_024-062" /locus_tag="ctg23_3" /protein_end="72" /protein_start="33" /score="39.1" /tool="antismash" /translation="FYLEQITMKVKGSLNIKCLEESMNVIMDRYDVFRTVFIH" CDS_motif 14196..14261 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_3_0003" /evalue="1.70E-11" /label="C3_DCL_135-156" /locus_tag="ctg23_3" /protein_end="166" /protein_start="144" /score="36.5" /tool="antismash" /translation="YHHIILDGWCFGIVVQDLFKVY" CDS_motif 14307..14345 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_3_0004" /evalue="5.50E-04" /label="C4_DCL_171-183" /locus_tag="ctg23_3" /protein_end="194" /protein_start="181" /score="12.4" /tool="antismash" /translation="PYKDYIKWLEKQD" CDS_motif 14583..14678 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_3_0005" /evalue="1.30E-18" /label="C5_DCL_263-294" /locus_tag="ctg23_3" /protein_end="305" /protein_start="273" /score="59.4" /tool="antismash" /translation="DLAFGTVVSGRPAEIKGVEHMVGLFINVVPRR" CDS_motif 14727..14840 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_3_0006" /evalue="1.00E-17" /label="C67_DCL_14fromHMM" /locus_tag="ctg23_3" /protein_end="359" /protein_start="321" /score="56.6" /tool="antismash" /translation="QEQSLQSEPHQYVPLYDIQSQADQPKLIDHIIVFENYP" aSDomain 15171..16364 /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg23_3_AMP-binding.1" /evalue="4.80E-110" /label="ctg23_3_AMP-binding.1" /locus_tag="ctg23_3" /protein_end="867" /protein_start="469" /score="359.8" /specificity="substrate consensus: Leu" /tool="antismash" /translation="FKEAVNVNPDALALTYFGQTLSYRELDEEANRLARRLQKHGAGKG SVVALYTKRSLELVIGILGVLKAGAAYLPVDPKLPEDRISYMLADSAAACLLTHQEMKE QAAELPYTGTTLFIDDQTRFEEQASDPATAIDPNDPAYIMYTSGTTGKPKGNITTHANI QGLVKHVDYMAFSEKDTFLSVSNYAFDAFTFDFYASMLNAARLIIADEHTLLDTERLTD LILQENVNVMFATTALFNLLTDAGEDWMKGLRCILFGGERASVPHVRKALRVMGPGKLI NCYGPTEGTVFATAHVVHDIPDSISSLPIGKPISNASVYILNEQSQLQPFGAIGELCIS GMGVSKGYVNRADLTKEKFIKNPFKPGETLYRTGDLARWLPDGTIEYAGRIDDQVKIR" CDS_motif 15357..15398 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_3_0007" /evalue="2.60E-05" /label="NRPS-A_a2" /locus_tag="ctg23_3" /protein_end="545" /protein_start="531" /score="17.4" /tool="antismash" /translation="LGVLKAGAAYLPVD" CDS_motif 15591..15650 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_3_0008" /evalue="9.20E-08" /label="NRPS-A_a3" /locus_tag="ctg23_3" /protein_end="629" /protein_start="609" /score="24.4" /tool="antismash" /translation="AYIMYTSGTTGKPKGNITTH" CDS_motif 16158..16247 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_3_0009" /evalue="5.50E-13" /label="NRPS-A_a6" /locus_tag="ctg23_3" /protein_end="828" /protein_start="798" /score="41.1" /tool="antismash" /translation="PFGAIGELCISGMGVSKGYVNRADLTKEKF" CDS_motif 16329..16394 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_3_0010" /evalue="9.60E-12" /label="NRPS-A_a8" /locus_tag="ctg23_3" /protein_end="877" /protein_start="855" /score="36.8" /tool="antismash" /translation="YAGRIDDQVKIRGHRIELEEIE" aSDomain 16683..16889 /aSDomain="PCP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg23_3_PCP.1" /evalue="1.50E-25" /label="ctg23_3_PCP.1" /locus_tag="ctg23_3" /protein_end="1042" /protein_start="973" /score="81.1" /tool="antismash" /translation="EETIAQIWSEVLGRKQIGIHDDFFALGGHSLKAMTAASRIKKELG IDLPVKLLFEAPTIAGISAYVKNG" aSDomain 16941..17540 /aSDomain="Thioesterase" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg23_3_Thioesterase.1" /evalue="5.40E-37" /label="ctg23_3_Thioesterase.1" /locus_tag="ctg23_3" /protein_end="1259" /protein_start="1059" /score="120.2" /tool="antismash" /translation="IIFAFPPVLGYGLMYQNLSSRLPSYKLCAFDFIEEEDRLDRYADL IQKLQPEGPLTLFGYSAGCSLAFEAAKKLEEQGRIVQRIIMVDSYKKQGVSDLDGRTVE SDVEALMNVNRDNEALNSEAVKQGLKQKTHAFYSYYVNLISTGQVKADIDLLTSGADFD MPEWLASWEEATTGAYRMKRGFGTHAEMLQGETLDRN" CDS_motif 17088..17162 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_3_0011" /evalue="6.30E-10" /label="NRPS-te1" /locus_tag="ctg23_3" /protein_end="1133" /protein_start="1108" /score="31.5" /tool="antismash" /translation="QPEGPLTLFGYSAGCSLAFEAAKKL" CDS 17620..18348 /NRPS_PKS="Domain: Thioesterase (14-231). E-value: 2.8e-55. Score: 180.1. Matches aSDomain: nrpspksdomains_ctg23_4_Thioesterase.1" /gene_functions="biosynthetic-additional (rule-based-clusters) Abhydrolase_6" /gene_functions="biosynthetic-additional (rule-based-clusters) PF00561" /gene_functions="biosynthetic-additional (smcogs) SMCOG1004:thioesterase (Score: 213.1; E-value: 5.1e-65)" /gene_kind="biosynthetic-additional" /locus_tag="ctg23_4" /sec_met_domain="Abhydrolase_6 (E-value: 5.4e-15, bitscore: 50.5, seeds: 455, tool: rule-based-clusters)" /sec_met_domain="PF00561 (E-value: 2.1e-06, bitscore: 21.4, seeds: 48, tool: rule-based-clusters)" /transl_table=11 /translation="MSQLFKSFDASEKTQLICFPFAGGYSASFRPLHAFLQGECEMLAA EPPGHGTNQTSAIEDLEELTDLYKQELNLRPDRPFVLFGHSMGGMITFRLAQKLEREGV FPQAVIISAIQPPHIQRKKVSHLPDDQFLDHIIQLGGMPAELVENKEVMSFFLPSFRSD YRALEQFELYDLAQIQSPVHVFNGLDDKKCIRDAEGWKKWAKDITFHQFDGGHMFLLSQ TEEVAERIFAILNQHPIIQP" aSDomain 17662..18312 /aSDomain="Thioesterase" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg23_4_Thioesterase.1" /evalue="2.80E-55" /label="ctg23_4_Thioesterase.1" /locus_tag="ctg23_4" /protein_end="231" /protein_start="14" /score="180.1" /tool="antismash" /translation="QLICFPFAGGYSASFRPLHAFLQGECEMLAAEPPGHGTNQTSAIE DLEELTDLYKQELNLRPDRPFVLFGHSMGGMITFRLAQKLEREGVFPQAVIISAIQPPH IQRKKVSHLPDDQFLDHIIQLGGMPAELVENKEVMSFFLPSFRSDYRALEQFELYDLAQ IQSPVHVFNGLDDKKCIRDAEGWKKWAKDITFHQFDGGHMFLLSQTEEVAERIF" CDS_motif 17845..17916 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg23_4_0001" /evalue="1.90E-08" /label="NRPS-te1" /locus_tag="ctg23_4" /protein_end="99" /protein_start="75" /score="26.7" /tool="antismash" /translation="PDRPFVLFGHSMGGMITFRLAQKL" CDS 18449..19675 /gene_functions="transport (smcogs) SMCOG1137:Major facilitator superfamily MFS 1 (Score: 335.7; E-value: 5.1e-102)" /gene_kind="transport" /locus_tag="ctg23_5" /transl_table=11 /translation="MRTSPRMKWFVLLFTFVFAIGMNSFRNSFQFFMLPMADAFHADRS LISVSVSIFMITTGIVQFFVGFFIDRFSVRKIMALGAVCISTSFLVLPYSPNVHVFSAI YGVLGGIGYSCAVGVTTQYFISRWFDIHKGLALAILTNANSAGLLLLSPIWAAAPYHAG WQSTYTILGIVMAAVLLPLLVFGMKHPPHAQAESVKKSYDWRGFWNVMKQSRLIHILYF GVFTCGFTMGIIDAHLVPILKDAHVSHVNGMMAAFGAFIIIGGLLAGWLSDLLGSRSVM LSILFFIRLLSLICLLIPILGIHHSDLWYFGFILLFGLSYTGVIPLTAASISESYQTGL IGSLLGINFFIHQVAGALSVYAGGLFFDMTHGYLLIVAVCIVFVGLSAVIELVPFLDKQ KAKETHHSI" CDS complement(19690..20247) /locus_tag="ctg23_6" /transl_table=11 /translation="MIQYASESINLPGEIAFKDVREIFFYQIAKISCFYFLLFCAIFTA VNFINGWPRIVYGSDALNLFMNSMLIIVMSVLFTLLLLLLLYVKFSRAYKKNERMKSKR TYTLNQEGIRICSKKYDLIFNWDEITAVFEYNNIFRVNTSSGQYIAIPKRFFHSKEEMN RFKEIILKNTGTKKLKFKKDQH" CDS complement(20301..21239) /gene_functions="transport (smcogs) SMCOG1166:transporter, EamA family (Score: 156.9; E-value: 1.2e-47)" /gene_kind="transport" /locus_tag="ctg23_7" /transl_table=11 /translation="MVKHQQAPAYIAATLYSFIIGLSFLFVKIALQTAEPFDILAHRFT IAFAAATVPILFGWVKLSIRVKDVIAILPLALLYPALFFSFQAFGLVYSSSSEAGIIQA AIPIFTMVFAAYVLKERPTWTQKGFTVLSVAGVMFIFVMKGVDVESASLKGSLLILLSA LSSAMYNTAARKMTQRFKLTELTYIMSAIGFVVFNAIALVRHGAAGTVGTYFLPFREPG FVLAIVYLGVLSSLVTSFLSNYTLSRIEAFKMSAFNHVSTIVTMIAGVVILNESLAWYH LAGAVCIMIGVVGSNINLEKKTKRPGMPAKK" CDS 21363..22697 /NRPS_PKS="Domain: Aminotran_1_2 (96-438). E-value: 1.4e-22. Score: 72.1. Matches aSDomain: nrpspksdomains_ctg23_8_Aminotran_1_2.1" /gene_functions="biosynthetic-additional (rule-based-clusters) Aminotran_1_2" /gene_functions="biosynthetic-additional (smcogs) SMCOG1019:aminotransferase (Score: 260.3; E-value: 4.8e-79)" /gene_kind="biosynthetic-additional" /locus_tag="ctg23_8" /sec_met_domain="Aminotran_1_2 (E-value: 6.2e-22, bitscore: 72.1, seeds: 48, tool: rule-based-clusters)" /transl_table=11 /translation="MEKYMSLVTRIEEMMQSTAYQEGDRLPSIRQLSARYQVSKSTVIR ALQELEKRHLIYSVPKSGYYIVKKTGKSKSGQLGPIDFATSAPDPDVFPYLDFQHCINK AIDTYKNDLFIYGTPKGLPSLIRVLRKLLATQQVFADERHIFITSGVQQALSLLCAMPF PNGKEKIAIEQPGYHLMVEQLETVGIPAIGVKRTEEGLDIAKVERLFQTESIKFFYTMP RFHNPLGCSLSERDKQELVRLAEAYDVYLVEDDYLGDLEENKKADPLYAYDLSSHVIYL KSFSKMMFPGLRVGAAVLPEALTDTFYAYKKLNDIDCSMISQAALEIYLKSGMYGRHKE KIRDSYKERSLRLHQAIRTHRQLGSGRFTFSSGQAPCMHTHLVLPQDLPASRVIHRLKK QGVLLEAIDRHYLSDYPKENLLKINISYVKTEDIERGVKLLMSHL" aSDomain 21651..22676 /aSDomain="Aminotran_1_2" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg23_8_Aminotran_1_2.1" /evalue="1.40E-22" /label="ctg23_8_Aminotran_1_2.1" /locus_tag="ctg23_8" /protein_end="438" /protein_start="96" /score="72.1" /tool="antismash" /translation="DFQHCINKAIDTYKNDLFIYGTPKGLPSLIRVLRKLLATQQVFAD ERHIFITSGVQQALSLLCAMPFPNGKEKIAIEQPGYHLMVEQLETVGIPAIGVKRTEEG LDIAKVERLFQTESIKFFYTMPRFHNPLGCSLSERDKQELVRLAEAYDVYLVEDDYLGD LEENKKADPLYAYDLSSHVIYLKSFSKMMFPGLRVGAAVLPEALTDTFYAYKKLNDIDC SMISQAALEIYLKSGMYGRHKEKIRDSYKERSLRLHQAIRTHRQLGSGRFTFSSGQAPC MHTHLVLPQDLPASRVIHRLKKQGVLLEAIDRHYLSDYPKENLLKINISYVKTEDIERG VK" CDS complement(22692..23366) /NRPS_PKS="Domain: ACPS (103-166). E-value: 6e-20. Score: 63.4. Matches aSDomain: nrpspksdomains_ctg23_9_ACPS.1" /gene_functions="biosynthetic-additional (smcogs) SMCOG1012:4'-phosphopantetheinyl transferase (Score: 189.2; E-value: 1.1e-57)" /gene_kind="biosynthetic-additional" /locus_tag="ctg23_9" /transl_table=11 /translation="MKIYGIYMDRPLSQEENERFMSFISPEKREKCRRFYHKEDAHRTL LGDVLVRSVISRQYQLDKSDIRFSTQEYGKPCIPDLPDAHFNISHSGRWVIGAFDSQPI GIDIEKTKPISLEIAKRFFSKTEYSDLLAKDKDEQTDYFYHLWSMKESFIKQEGKGLSL PLDSFSVRLHQDGQVSIELPDSHSPCYIKTYEVDPGYKMAVCAAHPDFPEDITMVSYEE LL" aSDomain complement(22869..23057) /aSDomain="ACPS" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg23_9_ACPS.1" /evalue="6.00E-20" /label="ctg23_9_ACPS.1" /locus_tag="ctg23_9" /protein_end="166" /protein_start="103" /score="63.4" /tool="antismash" /translation="IGIDIEKTKPISLEIAKRFFSKTEYSDLLAKDKDEQTDYFYHLWS MKESFIKQEGKGLSLPLD" CDS complement(23471..24118) /locus_tag="ctg23_10" /transl_table=11 /translation="MKQELVLRWTFYFAGLIILAFGVSLTIEGKALGISPWDAFHYSLF QHFGLTVGQWSIIIGALIVGFTSLFTRAWPKIGALLNMVLIGVFIDFFNFILPAPSTYT GSIIVFSLGVVLIGYGVGVYVSAGLGAGPRDSLMMLITEKTGWNVQWVRNGMEITILFA AWGMGGPIGFGTILTAILTGLILRFSLPQSIQLLNYAVARRTAAVKASPPVH" CDS complement(24439..25182) /gene_functions="transport (smcogs) SMCOG1000:ABC transporter ATP-binding protein (Score: 222.1; E-value: 1.3e-67)" /gene_kind="transport" /locus_tag="ctg23_11" /transl_table=11 /translation="MLTVKGLNKSFGENEILKKIDMKIEKGKVIAILGPSGSGKTTLLR CLNALEIPNRGELAFDDFSIDFSKKVKQADILKLRRKSGMVFQAYHLFPHRTALENVME GPIQVQKRNKEEVRKEAIQLLDKVGLKDKMDLYPFQLSGGQQQRVGIARALAIQPELML FDEPTSALDPELVGEVLKVIKDLANEGWTMVVVTHEIKFAQEVADEVIFIDGGVIVEQG PPEQIFSAPKEERTQRFLNRILNPL" CDS complement(25196..25900) /gene_functions="transport (smcogs) SMCOG1096:polar amino acid ABC transporter, inner membrane (Score: 244.4; E-value: 1.7e-74)" /gene_kind="transport" /locus_tag="ctg23_12" /transl_table=11 /translation="MFLNNLPALTLGTAIPWDLVQQSFWPILSGGIYYTIPLTILSFIF GMILALITALARMSKVRPLRWVFSVYVSAIRGTPLLVQLFIIFYLFPAFNVTLDPFPSA VIAFSLNVGAYASEIIRASILSVPKGQWEAGYTIGMTHQKTLFRVILPQAFRVSIPPLS NTFISLIKDTSLASQILVAELFRKAQEIGARNLDQILVIYIEAAFIYWIICFLLSLVQH VIERRLDRYVAK" CDS complement(25887..26693) /gene_functions="biosynthetic-additional (smcogs) SMCOG1091:glutamine-binding lipoprotein glnH (Score: 234.5; E-value: 1.7e-71)" /gene_kind="biosynthetic-additional" /locus_tag="ctg23_13" /transl_table=11 /translation="MKKALLALFMVVSIAALAACGAGNDNQSKDNAKDGDLWASIKKKG VLTVGTEGTYEPFTYHDKDTDKLTGYDVEVITEVAKRLGLKVDFKETQWDSMFAGLNSK RFDVVANQVGKTDREDKYDFSDKYTTSRAVVVTKKDNNDIKSEADVKGKTSAQSLTSNY NKLATNAGAKVEGVEGMAQALQMIQQGRVDMTYNDKLAVLNYLKTSGNKNVKIAFETGD PQSTYFTFRKGSGEVVDQVNKALKEMKEDGTLSKISKKWFGEDVSK" CDS complement(26809..27681) /gene_functions="regulatory (smcogs) SMCOG1014:LysR family transcriptional regulator (Score: 246.3; E-value: 6.3e-75)" /gene_kind="regulatory" /locus_tag="ctg23_14" /transl_table=11 /translation="MDIRQLRYFITIAQEQKITSAAKKLHMAQPPLSRQLKQLEDELGV VLFDRNKKKQMTLTYEGAVFLKRAKEILHRFEDAVIEVQELKEEVAGTLAVGSTIYCAA LMLEKVTQIKERYPHLTFNIWENEPATLLELLESRQIDAAVTTTLIKSDTVQFKQLDDI PCVLVLSDEAGYPCGDTIKMEDIPSFPLILLRPVNGKGVYNQVMNEFHRLNLEPRIVCE CHDSATLLSLVSSGFGASILPVTMIPVHMRNHVHTVHIENNPFIMTPAVMWRTDSYLPK PAQQFLDLF" CDS 27771..28385 /gene_functions="biosynthetic-additional (rule-based-clusters) Flavoprotein" /gene_kind="biosynthetic-additional" /locus_tag="ctg23_15" /sec_met_domain="Flavoprotein (E-value: 1.8e-32, bitscore: 105.9, seeds: 143, tool: rule-based-clusters)" /transl_table=11 /translation="MKAEFKRKGGGKVKLVVGMTGATGAIFGVRLLQWLKAAGVETHLV VSPWANVTIKHETGYTLQEVEQLATYTYSHKDQAAAISSGSFDTDGMIVAPCSMKSLAS IRTGMADNLLTRAADVMLKERKKLVLLTRETPLNQIHLENMLALTKMGTIILPPMPAFY NQPSSLEEMVDHIVFRTLDQFGIRLPEAKRWNGIEKQKGGA" CDS 28388..29809 /locus_tag="ctg23_16" /transl_table=11 /translation="MAYQDFREFLAALEKEGQLLTVNEEVKPEPDLGAAARAASNLGDK SPALLFNNIYGYHNARIAMNVIGSWPNHAMMLGMPKDTPVKEQFFEFAKRYDQFPMPVK REETAPFHENEITEDINLFDILPLFRINQGDGGYYLDKACVISRDLEDPDNFGKQNVGI YRMQVKGKDRLGIQPVPQHDIAIHLRQAEERGINLPVTIALGCEPVITTAASTPLLYDQ SEYEMAGAIQGEPYRIVKSKLSDLDVPWGAEVVLEGEIIAGEREYEGPFGEFTGHYSGG RSMPIIKIKRVYHRNNPIFEHLYLGMPWTECDYMIGINTCVPLYQQLKEAYPNEIVAVN AMYTHGLIAIVSTKTRYGGFAKAVGMRALTTPHGLGYCKMVIVVDEDVDPFNLPQVMWA LSTKMHPKHDAVIIPDLSVLPLDPGSNPSGITHKMILDATTPVAPETRGHYSQPLDSPL TTKEWEQKLMDLMNK" CDS 29826..30053 /locus_tag="ctg23_17" /transl_table=11 /translation="MHTCPRCDSKKGEVMSKSPVEGAWEVYQCQTCFFTWRSCEPESIT NPEKYNPAFKIDPKETETAIEVPAVPERKA" CDS 30050..30514 /locus_tag="ctg23_18" /transl_table=11 /translation="MIGVNSMSDRLFELLDGRCLNEKQHEAFVLQTVSEDGWPHAAMIS AGEIIALSRTDIRIALWKNTMTSANILRTGKAQFTAWWKGAAYYVKLECAPLPPLKDAE YDRDRFSCRIVSVKEDVAKYADLTSGVRIQLHSPEEVLGRWEKTLEDLKR" CDS 30580..31425 /gene_functions="biosynthetic-additional (rule-based-clusters) PF00561" /gene_functions="biosynthetic-additional (rule-based-clusters) Abhydrolase_6" /gene_functions="biosynthetic-additional (smcogs) SMCOG1036:alpha/beta hydrolase fold protein (Score: 65.1; E-value: 1.3e-19)" /gene_kind="biosynthetic-additional" /locus_tag="ctg23_19" /sec_met_domain="PF00561 (E-value: 1.4e-14, bitscore: 48.3, seeds: 48, tool: rule-based-clusters)" /sec_met_domain="Abhydrolase_6 (E-value: 3.3e-09, bitscore: 31.6, seeds: 455, tool: rule-based-clusters)" /transl_table=11 /translation="MERAGICHSDGFDLAYRIEGEGAPILVIGSAVYYPRLFSSDIKQK YQWVFVDHRGFAKPKRELRAEDSRLDAVLADIERMRTFLQLEDVTILGHSGHAFMALEY ARTYPKQVRKVALFNTAPDNSEERQRKSESFFMETASLERKKRFEKDIANLPQDIDKDP ERRFVHMCIRAEAKSFYQERPHAAALWDGVFTNMPIMDELWGNTFAQIDLIQRLADVRM PVYIGLGRYDYLVAPVALWDAVDGLYSHVDKVIFERSGHQPMLEEPEAFDQSFSKWLDQ " CDS complement(31466..32944) /gene_functions="transport (smcogs) SMCOG1202:major facilitator transporter (Score: 52.1; E-value: 6.3e-16)" /gene_kind="transport" /locus_tag="ctg23_20" /transl_table=11 /translation="MASIDNESIIKSVPQKGFFGHPRGLFTLFFTEFWERFSYYGMRAI LLYYLYTETVNGGLGFDKGTAVAIMSIYGSLVYMSTIIGGWLADRVFGTANTVFYGGIF IMFGHIALAYPGSAIAFYISMVLIIVGTGLLKPNVSSVVGDLYTKEDPRRDSGFSIFYM GINLGGLLAPLIVGTLGQKYNYHLGFGAAAVGMLLGLIVFALTRKKNLGLAGSNVPNPL SKKSAIGTGIGVIIVAIAVMISVQTGVLTINRFIDLVSILGILIPVIYFIIMFTSKKAD STEKSRLAAYIPLFIGAVMFWAIQEQGATILAVYADERIRLSLGGFELQSSWFQSLNPL FVVIFAPIFAWLWMKLGKRQPSTPVKFSIGIILAGLSFIIMVFPAMQGKEALVSPLWLV LSFLLVVLGELCLSPVGLSVTTKLAPAAFSAQTMSMWFLTNAAAQAINAQVAGLFDKIP ETMYFGTIGLISIVLGGILLLLSPVIKRAMKGVL" CDS 33224..34978 /locus_tag="ctg23_21" /transl_table=11 /translation="MAEFILNAADFGVPGDGKTDSTERINQCLSTAVSKGYHTVWFPKG TYLIDATLGGDLNQRFRNAGIIVPGNLEIMMDPECIMKVIPNSSWGYSAFYVGKQENIT ISGGQIIGERDEHTYASAGIRSTHEWGFGICIEGCSNVVIDDVKISDFTGDGIIVSPRG LKTNQDYRTSEQIIIRRCEVRRSRRNNISITGCDMVTVEACLIEDAGTGNGTAPKFGID IEGYGEGDVDYEEPINVSIRNNHFVGNVSSSVTNFNGYGILIEGNHSDNTISYGYGTQT VIKGNILRRPEDAAAAPRVGITGLGVSQGKETSDAVIAGNLITGFSTGIDVRGKSVLVT NNKISNFENTGILVYQSSDVKVDGNQIQNGLSETRRSIGLRAVLSDDTAFLNNCLIQVV DGVSVSGGNMIIKDNLLRKFSRGIWIAQGDAVIEGNTLNPGAFEAVPESYSVSVTNNAG AIIKNNTFKEFKNYPIYCSTSAKTSIIGNHLERSPLLVTIYISAGVHEIFDNTISVNRT AGNPIVIYLNGSAGSIIAGNTINNLSAGTATAIQTNTSTNSKIIGNRIFKGTINKHSSD AIDGNIIV" CDS complement(34993..35214) /locus_tag="ctg23_22" /transl_table=11 /translation="MKILGVTGVILICLLAISVLMDMLQGFSLTKAIYNNMSSFKMTTF AEWVVLLFFVLVLVREMYVIYKSKKKNP" CDS 35340..36974 /locus_tag="ctg23_23" /transl_table=11 /translation="MPLFSKRKNNTSSKDKRNTEEKNQEQKQEKERPVLISPSLAKNIA ETKKEVGSSSDVIIREIKIGEQDHVHLAVIYIAGLVDNNTIHESLIDPLVQDESIQNTH AIQQILEKTLPLGGVKAEKSWDKLFSELMLGNALIFADGYDEALICSTQGGEQRSIQEP STQVSFRGPRQGFTESLQTNISMIRRYIKNPNLWVEKMKKGSVTNTDIALMYIQGICDE KVLKEVKQRLEKIDIDSILESGYIEQLIEDETFTTFPTMYHTERPDVVAGNLLEGRFAI IVDGTPFVLIAPALFVQFFQSVEDYYSRFDIATSIRILRVLVFFISLVAPAVYVAATTF HQEMIPTQLLVVIAAQREIVPFPAVVEALTMEVAFEILREAGVRLPRVVGSAVSIVGAL VIGQAAVQAGIVSPAMVIIVALTAIASFATPAFAMAISARLIRFIFIIASAVMGFYGLI LGIIMMFVHLCSLRSFGVPYMSPLAPFSSQGVKDALFRVPWWADEKRPESVSKEDKVRQ GQDQRPEPAASRGMVNKDLEEGDQNGT" ORIGIN 1 ttctcacgaa gccgtcgctt gaaatgtccg ccgcggtgct cggcgtcttg aaagccggag 61 cggcgtttgt gccgattgat cctgactacc cggatcagcg gattgagtat attttacagg 121 acagcggcgc gaagcttctc ttgaaacagg aaggcatttc agtgccggac agctttacgg 181 gagatgtcat tcttctcgac ggaagccgca cgattctaag cctgccgctt gatgaaaacg 241 acgagggaaa tccagaaacc gctgtaaccg cggagaactt ggcgtacatg atttacacgt 301 ctggaacgac cggacagccg aagggtgtca tggtcgagca ccatgcgctt gtgaacctgt 361 gcttctggca ccacgacgcg ttcagcatga cagcggagga ccgcagtgcg aagtacgcgg 421 gcttcgggtt cgacgcttcc atttgggaga tgttcccgac ctggacgatc ggcgccgaac 481 ttcacgtcat tgatgaagcg atccgcctcg atatcgtccg cctgaacgat tattttgaaa 541 cgaacggcgt aacgatcacg ttcctgccga cacagcttgc ggaacagttc atggagcttg 601 agaacacatc acttcgcgtc ctcttgaccg gaggagacaa gctgaagcgc gcagtgaaaa 661 agccgtacac actcgtcaac aactacgggc cgacagaaaa tacggtcgtt gccacaagcg 721 cagaaatcca tccggaggaa ggctcgcttt ccatcggaag ggccattgcc aatacgagag 781 tatacattct cggagagggc aatcaggtgc agccggaagg cgtagccgga gagctttgtg 841 tggcgggacg cggattagcg cgaggctatc tgaatcgaga agacgaaacc gcgaagcggt 901 ttgtcgctga tccgtttgtg ccgggtgaac gcatgtaccg caccggcgac ttggtgaagt 961 gggtgaacgg cggcatcgaa tacatcggcc ggatcgacca gcaggtcaag gtccgcggct 1021 accggatcga gctctcagaa attgaagtcc agctcgccca gctttctgag gtgcaggatg 1081 cggcggtaac agctgtcaaa gataaaggcg gcaatacagc gatcgcggcg tatgtcaccc 1141 cggaaacagc tgatatagaa gcgctgaaat cagcactgaa ggaaaccctg ccggattata 1201 tgatcccggc gttctgggtg acactgagcg agcttccggt cacggcaaac ggcaaagtcg 1261 accgcaaagc cttgcctgag ccggacatcg aagcgggaag cggagaatac aaagcgccga 1321 cgaccgacat ggaagagctg cttgccggca tctggcagga cgtgcttgga atgtctgaag 1381 tcggtgtcac cgacaatttc ttctcgcttg gcggagattc catcaaagga attcaaatgg 1441 cgagccgctt gaatcagcac ggctggaagc tggaaatgaa agatctcttc cagcatccga 1501 cgatcgaaga gcttacccaa tatgtagagc gtgccgaagg caaacaggca gaccaaggcc 1561 cggtagaggg cgaagtcatc ctgacgccga tccagcgctg gttctttgaa aagaacttca 1621 cgaacaagca ccactggaac caatcggtga tgcttcacgc cgcgaagggc tttgaccctg 1681 aacgggtgga gaaaacattg caggcgctga tcgagcatca tgacgcgctc cgtatggtct 1741 atcgtgaggg acaggaagac gtcattcaat acaacagagg tcttgaagct gcttccgctc 1801 aattggaggt catccagatt gagggccaag ctgcagatta cgaagaccgt atagagagag 1861 aagcagagcg tttgcaaagc agcatcgact tgcaggaagg cggcttgtta aaagcaggct 1921 tgttccaagc ggaagacgga gaccacttgc ttctcgccat tcaccactta gtggttgacg 1981 gcgtctcgtg gcggattcta ctggaggatt tcgccgcagt atatacacag cttgagcaag 2041 gcaatgaacc ggttttcccg cagaaaacac attcatttgc agagtatgca gagagattgc 2101 aagacttcgc gaactccaaa gcctttttga aagaaaaaga gtattggaga cagcttgaag 2161 aacaagctgt cgcggcaaag cttccgaaag accgcgaatc tggtgatcag cgaatgaaac 2221 atacaaagac aattgaattc tcgctgactg ctgaagagac agaacagctc accacaaagg 2281 tgcatgaggc atatcacaca gaaatgaatg atattttgct gacggcattc ggattggcaa 2341 tgaaggagtg gacgggtcag gatcgagtaa atgttcattt agaggggcat ggacgtgaag 2401 aaatcataga agacctgacc atttcccgca cagtcggctg gtttacaagt atgtacccaa 2461 tggtgctcga tatgaagcat gcggatgatc tgggctacca gctgaagcaa atgaaagaag 2521 atatcagaca tgtgccgaat aagggagtcg gatacggcat tctgcgctat ctgacggcac 2581 cggaacataa agaagatgtg gcgttctcga ttcagccgga tgtcagcttc aactatttag 2641 gtcagtttga cgaaatgtcg gatgcaggtt tgtttacaag atcagagctg ccatcaggac 2701 agtcattaag ccctgaaaca gaaaaaccga atgcgctgga tgttgtcgga tatatcgaaa 2761 acggaaaact gacgatgtca ctggcctatc attctcttga atttcatgaa aaaacagtac 2821 aaacattcag tgacagcttt aaagcgcatc ttctcagaat cattgaacat tgcctatctc 2881 aagacggtac ggaactgacc ccgagtgatc ttggtgacga cgatttgacg ctggatgagc 2941 tggataaatt aatggaaatt ttctaataga ggtggcatat gagcaaaaaa tcgattcaaa 3001 aggtgtacgc actgacacca atgcaggagg gaatgctgta tcatgcgatg cttgatccgc 3061 attcttcctc gtacttcaca caattagagc ttgggattca cggcgctttt gatcttgaaa 3121 tctttgagaa aagcgtcaat gaactgattc ggtcatacga tattctccgt acggtatttg 3181 tgcatcagca gctgcaaaaa ccgcgtcagg tcgtgttagc ggaacgcaaa acaaaggtgc 3241 attatgagga tatcagtcat gcagacgaga accgccagaa agagcacatt gagcgttaca 3301 aacaagacgt tcagcgccaa ggctttaacc tggcaaaaga catattgttc aaggtagcgg 3361 ttttccgcct tgatgcagat cagctgtatc ttgtctggag caatcatcat attatgatgg 3421 acggctggag catgggcgtc ctcatgaaaa gcctgttcca aaactatgaa gcgctcagag 3481 caggaaggac acctgcaaac ggtcaaggca agccttactc cgactacatc aaatggcttg 3541 gaaaacagga caatgaagaa gcggagagct actggagcga gcgcttggcg ggttttgaac 3601 agccaagcgt gctcccgggc cgcctgcctg taaaaaaaga cgaatacgtc aataaagaat 3661 attcctttac atgggacgaa acactggttg cccgcattca gaaaaccgca aaccttcatc 3721 aagtgacagg gcctaaccta tttcaggccg tttgggggat tgttctcagc aaatacaact 3781 ttacggatga tgtgatcttc ggaacggtcg tctcgggacg accgtctgaa atcaacggaa 3841 tcgaaacgat ggcggggctg tttatcaaca ccattccagt gcgggtgaaa gttgaacgag 3901 atgctgcatt cgctgatatt ttcacagctg ttcagcagca tgcagtagag gcagagcgtt 3961 acgattacgt gccgctctat gagattcaaa aacgctcagc ccttgatggc aatctcttaa 4021 accatctggt cgcgtttgaa aattatccgc ttgatcaaga gcttgaaaac ggcagcatgg 4081 aagaccgcct cgggttttcg attaaggtag aaagcgcatt tgaacaaacg agcttcgatt 4141 tcaacctgat tgtgtatcca ggcaaaacat ggaccgtcaa aattaaatat aacggagccg 4201 cctttgattc cgcttttatc gaacggacag cggagcacct tacccgcatg atggaagcag 4261 ctgtcgatca gccggccgct tttgtgcgtg agtacgggct tgtgggagac gaagagcagc 4321 gtcaaattgt cgaggtgttt aacagcacga aagccgaact ccctgaagga atggctgttc 4381 accaagtgtt tgaagagcaa gcgaaacgga cgccggcgag cactgccgtc gtatatgaag 4441 gaaccgagct gacgtaccgt gagctgaatg cagcggctaa ccgtctggcg agaaagcttg 4501 tcgaacaagg ccttcaaaaa ggggaaacag cagcgattat gaacgaccgc tcagtagaaa 4561 ccgttgtcgg catgctggct gtgttaaaag caggcgctgc atatgtgccg cttgatccag 4621 cgcttccggg ggatcgtctt cgtttcatgg cagaggacag ctccgttcga atggttttga 4681 ccggaaattc ttatacaggg caggcacatc agctgcaggt gccagttctt acactggaca 4741 taggcattga agatggcgaa gctgacaatc tcaacctgcc atccgccccg tctgatttgg 4801 cgtacatcat gtacacatcc ggttcaacgg gcaaaccgaa aggcgtcatg atcgaacata 4861 aaagcattct gcgcctcgtc aaaaatgccg ggtacgttcc tgttactgaa gaggaccgca 4921 tggcgcaaac aggggcagtc agctttgatg ccggaacgtt tgaggtattc ggcgcactgc 4981 tgaatggcgc agcgctttat ccggtcaaaa aagagacact gcttgatgcg aaacaatttg 5041 ctgcattcct gcgtgagcaa agcatcacaa ccatgtggct gacatcacct ttattcaacc 5101 agcttgctgc aaaggatgcg ggtatgttcg gcacactgcg ccatttaatc atcggcggag 5161 acgcccttgt cccgcatatt gtcagcaaag taaaacaggc atcgccgtcg ctttcattgt 5221 ggaacggata cggcccgaca gaaaacacga cgttttcaac cagttttctg atcgaccgcg 5281 agtatggcgg ctctatccca atcgggaagc cgatcggtaa ttccactgcc tacatcctgg 5341 atgagcagca atgcctgcag ccaatcggcg cgcctggtga gctttgcgta ggcggaatcg 5401 gtgtagcgcg tgggtatgtc aatctccctg agctgacaga gaagcaattt ctcgaagatc 5461 cgttcagacc gggtgagaga atttatcgca ctggtgactt ggcaagatgg ctgccggacg 5521 gcaatatcga atttttaggc agaatcgaca accaagtgaa ggtgcgcggc ttccgaattg 5581 agcttggcga aattgaaaca aaactgaaca tggctgagca tgtgacagag gctgtggtga 5641 tcatccgcaa gaacaaagcg gatgaaaatg aaatttgcgc gtactttacg gcggaccgtg 5701 aagtggctgt gagcgagctg agaaaaacac tgtctcagtc tttgcctgac tatatggtcc 5761 ctgcccacct gattcaaatg gacagtctgc cgctcacgcc aaacgggaaa atcaacaaaa 5821 aagaactgcc tgcaccgcaa tcagaagccg tgcagccgga atacgcagca ccagaaacag 5881 agagtgaaaa gaaattagcg gagatctggg aaggaatact cggcgtcaga gcaggcgtta 5941 ccgataactt ctttatgatc ggcggccatt ctttgaaagc gatgatgatg acggcgaaaa 6001 ttcaagagca ttttcataag gaagttccga taaaagtgct ttttgaaaag ccgactattc 6061 aagaactggc actgtatttg gaagagaacg aaagcaagga ggagcagacg tttgaaccga 6121 tcaggcaagc atcttatcag cagcattatc ctgtatcccc ggcccagcgg agaatgtata 6181 tcctcaatca gcttggacaa gcaaacacaa gctacaacgt ccccgctgta cttctgctgg 6241 agggagaagt agataaagcc cggcttgaaa acgcgattca gcaattaatc aaccggcacg 6301 aaatcctccg tacatcgttt gacatgatcg acggagaggt tgtgcaaacc gttcataaaa 6361 acatatcgtt ccagctggag gctgccaagg gacgggaaga agacgcggaa gagataatca 6421 aagcatttgt tcagccgttt gaattaaacc gcgcgccgct cgtccgttcg aagcttgtcc 6481 agctggaaga aaaacgccac ctgctgctca ttgatatgca tcatattatt actgacggaa 6541 gttcaacagg cattctaatc ggtgatcttg ccaaaatata tcaaggcgca gatctggaac 6601 tgccacaaat tcactataaa gattacgcag tttggcacaa agaacaaact aattatcaaa 6661 aagatgagga atactggctc gatgtcttta aaggcgaact gccaatactg gatcttcccg 6721 cggatttcga gcggccagct gaacggagct ttgcgggaga gcgcgtgatg tttgggcttg 6781 ataagcaaat cacggctcaa atcaaatcgc tcatggcaga aacagatacg acaatgtaca 6841 tgtttttgct ggcggcgttc aatgtactcc tttccaagta cgcgtcacag gatgatatca 6901 ttgttggctc gccgacagct ggcagaacac atcctgatct gcaaggtgtg ccgggtatgt 6961 ttgtcaacac ggtggcactc agaacggcac cagcgggaga taaaaccttc gcgcaatttc 7021 ttgaagaggt caaaacagcc agccttcaag cattcgagca ccagagctat ccgcttgagg 7081 agttgattga aaagcttccg cttacaaggg atacaagcag aagtccgctg ttcagcgtga 7141 tgttcaacat gcagaatatg gagattcctt cattaagatt aggagatttg aagatttcct 7201 cgtattccat gcttcatcat gttgcgaaat ttgatctttc cttggaagcg gtcgagcgtg 7261 aagaggatat cggcctaagc tttgactatg cgactgcctt gtttaaggac gagacgatcc 7321 gccgctggag ccgccacttt gtcaatatca tcaaagcggc cgcggctaat ccgaacgttc 7381 ggctgtctga tgtagatctg ctttcatctg cagaaacggc tgctttgcta gaagaaagac 7441 atatgactca aattaccgaa gcaacctttg ccgctctttt tgaaaaacag gcccagcaaa 7501 cacctgacca tcctgcggtg aaggctggcg gaaatctgct gacctatcgc gagctcgatg 7561 aacaggcgaa ccagctggcg catcatcttc gtgcccaagg ggccggaaat gaagacattg 7621 tcgcgattgt tatggaccgg tcagctgaag tcatggtatc cattctcggt gtcatgaagg 7681 cgggggcagc tttccttccg attgatcctg atacacctga agaacgaatc cgttattcat 7741 tagaggacag cggagcaaaa attgcggtcg tgaatgaaag aaacatgacg gctattgggc 7801 aatatgaagg gacaatcgtc agccttgatg acggtaaatg gagaaatgaa agcaaggagc 7861 gcccatcatc catttccggg tctcgcaatc ttgcatacgt catttatacg tccggtacga 7921 ccggaaagcc aaagggcgtg cagattgagc atcgtaatct gacaaactat gtctcttggt 7981 ttagtgaaga ggcgagcctg acggaaaatg ataagactgt attgctttca tcttacgcat 8041 ttgaccttgg ctatacgagc atgttccctg tacttctggg cgggggcgag ctccatatcg 8101 tccagaagga aacctatacg gcgccggatg aaatagcgca ctatatcaag gagcatggga 8161 tcacatatat caagctgaca ccgtctctgt tccatacaat agtgaacacc gccagttttg 8221 caaaagatgc gaactttgaa tccttgcgct tgatcgtctt gggaggagaa aaaatcatcc 8281 cgactgatgt tctcgccttc cgtaagatgt atggacatac cgaatttatc aatcactacg 8341 gcccgacaga agcaacgatc ggcgccattg ccgggcgggt tgatctgtct gagccggatg 8401 catttgcgaa acgcccgaca atcggacgcc cgattgcgaa tgccggcgcg cttgtcttaa 8461 atgaagcatt gaagcttgtg ccgccgggag cgagcggaca gctctatatc acgggacagg 8521 ggcttgcgag agggtatctc aacaggcctc agctgacagc cgagagattt gtagaaaatc 8581 catattcgcc gggaagcctc atgtacaaaa ccggagatgt cgtacgaaga ctttctgacg 8641 gtacgcttgc atttatcggc cgggctgatg atcaggtgaa aatccgaggc taccgcattg 8701 agccgaaaga aattgaaacg gtcatgctca gcctcagtgg aattcaagaa gcggttgtac 8761 tagcggtttc cgagggcggt cttcaagagc tttgcgcgta ttatacgtcg gatcaagata 8821 ttgaaaaagc agagctccgg taccagcttt ccctaacact gccgtctcat atgatccctg 8881 ctttctttgt gcaggttgac gcgattccgc tgacggcaaa cggaaaaacc gacagaaacg 8941 ctctgccgaa gccgaacgcg gcacaatccg gaggcaaggc cttggccgca ccggagacag 9001 cgcttgaaga aagtttatgc cgcatttggc agaaaacact tggcatagaa gccatcggca 9061 ttgatgacaa ttttttcgat ttaggcggcc attcattaaa agggatgatg ctgattgcca 9121 acattcaggc ggaattggag aaaagcgtac cgcttaaagc actgttcgag cagccgactg 9181 ttcgccagct ggcggcttat atggaggcgt ctgccgtttc aggcggccat caagtcctca 9241 aaccggctga caagcaggct atatatccat tgtcatccgc acagaaacgg atgtacgtgc 9301 tcaatcagct tgaccgccag acgataagct acaacatgcc atctgttctt ctaatggaag 9361 gagagcttga tatttcgcgc ctgcgcgact cactcaatca gcttgtgaat cgtcacgaat 9421 cattgcggac gtcatttatg gaagctaatg gtgagcctgt tcagcgcatc attgagaagg 9481 cggaggttga tcttcatctg tttgaagcca aagaagacga agcggaccaa aagattaagg 9541 aatttatccg gccattcgac ttaaacgacg caccgctcat tcgcgcagct ttgcttcgaa 9601 tagaagcgaa aaaacatttg ctgcttttag atatgcatca tatcatcgca gacggcgtct 9661 caagaggcat ttttgtaaaa gaattggcgc tgctttacaa aggagagcag cttccggagc 9721 cggcgcttca ttataaagat ttcgccgttt ggcaaaatga agctgagcaa aaagaacgga 9781 tgaaggagca tgaggcgtac tggatgtcag ttctttctgg cgagctgcca gagcttgatc 9841 tcccgctcga ttatgcccgt ccgcctgtgc aaagctttaa aggagatacg atccgtttcc 9901 gtacgggaag tgagacggca aaggcggtag aaaaattgct tgcggaaacc ggaacgacct 9961 tgcacatggt gctccatgct gttttccacg tctttttaag caaaatttcc ggacagcggg 10021 atatcgtcat cggctccgtt actgccggcc ggacgaatgc tgatgttcag gacatgccgg 10081 gaatgttcgt caatacactt gccctgagaa tggaagcgaa agaacagcaa acatttgcgg 10141 agcttttgga gcaagcaaag cagacgaacc tgtcagcgct tgagcatcag gagtatccgt 10201 ttgaagatct ggttaatcag cttgatctcc ctcgggatat gagccgaaac ccattgttta 10261 atgtgatggt gacgacagaa aaccctgata aagaacagct tacattgcaa aatctgagca 10321 tttcacctta tgaggctcat cagggaactt ctaagtttga tctgacactg ggcggattta 10381 ctgatgaaaa tggcattggc ttgcagctcg aatatgcgac agatctgttc gcgaaagaaa 10441 cagttgaaaa atggagcgaa tacgttctgc ggctactaaa ggctgttgcg gataacccga 10501 accagccgct ttccagcctg tcactggtca ccgagacaga aaaacaagca cttcttgagg 10561 catggaaggg caaagcgctg cctgtgccga cagacaaaac ggttcatcag ctattcgaag 10621 agactgtcca gcgccacaaa gaccgcccgg ctgtcacata caacggccag tcttggacgt 10681 acggcgagct gaatgcgaag gcaaaccgtc ttgcacggat tttgatggac tgcggcatca 10741 gcccggatga ccgcgtcggc gttctcacga agccgtcgct tgaaatgtcc gccgcggtgc 10801 tcggcgtctt gaaagccgga gcggcgtttg tgccgattga tcctgactac ccggatcagc 10861 ggattgagta tattttacag gacagcggcg cgaagcttct cttgaagcaa gaaggcattt 10921 cagtgccgga tagcttctca ggagacgtca ttcttctcga cggaagccgc acgattctaa 10981 gcctgccgct tgatgaaaac gacgagggaa atccagagac ggctgtaacc gcggagaact 11041 tggcgtacat gatttacacg tctggaacga ccggacagcc gaagggtgtc atggtcgagc 11101 accatgcgct tgtgaacctg tgcttctggc accacgacgc gttcagcatg acagcggagg 11161 accgcagtgc gaagtacgcg ggcttcgggt tcgacgcttc catttgggag atgttcccga 11221 cctggacgat cggcgccgaa cttcacgtca ttgatgaagc gatccgcctc gatatcgtcc 11281 gcctgaacga ttattttgaa acgaacggcg taacgatcac gttcctgccg acacagcttg 11341 cggaacagtt catggagctt gagaacacat cacttcgcgt attgctcact ggaggagaca 11401 agctgaagcg ggcagtgaaa aagccgtaca cactcgtcaa caactacggg ccgacagaaa 11461 atacggtcgt tgccacaagc gcagaaatcc atccggagga aggctcgctt tccatcggaa 11521 gggccattgc caatacgaga gtatacattc tcggagaggg caatcaggtg cagccggaag 11581 gcgtagccgg agagctttgt gtggcgggac gcggattagc gcgaggctat ctgaatcgag 11641 aagacgaaac cgcgaagcgg tttgtcgctg atccgtttgt gcctggtgag cgcatgtacc 11701 gcaccggcga tttggtgaaa tggacgggcg gcggcatcga atacatcggc cggatcgacc 11761 agcaggtcaa ggtccgcggc taccggatcg agctctcaga aatcgaagtc cagctcgccc 11821 agctttctga ggtgcaggat gcggcggtaa cagctgtcaa agataaaggc ggcaatacag 11881 cgatcgcggc gtatgtcaca ccggaaacag ctgatataga agcgctgaaa tcagcactga 11941 aggaaaccct gccggattac atgatcccgg cgttctgggt gaagctgaac gagcttccgg 12001 ttacggcaaa cggcaaggtg gaccgcaaag ccttgcctga gccggacatc gaagcgggaa 12061 gcggagaata caaagcgccg acgaccgaca tggaagagct gcttgccggc atctggcagg 12121 acgtgcttgg aatggctgaa gtcggtgtca ccgacaattt cttctcgctt ggcggagatt 12181 ccatcaaagg aattcaaatg gcgagccgct tgaatcagca cggctggaag ctggaaatga 12241 aagatctctt ccagcatccg acgatcgaag agctcaccca gtacgtagag cgtgccgaag 12301 gcaaacaggc agaccaaggc ccggtggagg gcgaagtcat cctgacgccg atccagcgct 12361 ggttctttga aaagaacttc acgaacaagc accactggaa ccaatcggtg atgcttcacg 12421 ccaagaaggg ctttgatcct gaacgggtgg agaaaacatt gcaggcgctg atcgagcatc 12481 atgacgcgct ccgtatggtc tttcgtgagg aaaacgggga catcgttcag gcgtatcaac 12541 cgatcggtga gagcgaggtc agcttcgaaa tcgtggatct gtacggctcc gatgaagaga 12601 tgctgagaag ccagattaaa attctcgcga acaagctgca gagcagtctc gatctgcaaa 12661 acgggccgct tctaaaggcg gagcaatatc gcacagaagc tggggatcac ctgctcattg 12721 ctgtacacca tctggtggtc gacggtgtgt catggcggat tttgcttgaa gactttgctt 12781 caggctacat gcaggctgag aaagaagaga gccttgtctt cccgcaaaaa acaaactcct 12841 tcaaggactg ggcggaagaa ctggcggcat tcagccaatc agcgcatctt ttacagcagg 12901 ctgaatactg gtcgcaaatt gccgctgaaa aggtttctcc tttaccgaag gattgtgaaa 12961 cagagcagcg gatcgtcaag gatacatcat ctgtcctatg tgaattaacg gaagaagaca 13021 cgaagcatct tttaacagat gttcatcagc catatggaac tgaaatcaac gatattcttc 13081 tcagcgcgct cggtttgaca atgaaagaat ggacaaaggg ggccaaaatt ggcattaacc 13141 ttgagggaca cggccgggag gacattatcc cgaatgtgaa tatctccaga acggtcggct 13201 ggtttacggc acaataccct gttgtgctcg acatatctga cgcagatgcc tcggctgtga 13261 tcaaaacagt caaagaaaac ctgcgccgca ttccggacaa aggtgttggc tacggcattc 13321 ttcgttattt cacagaaaca gcggaaacaa agggcttcac accggagatc agcttcaact 13381 atttgggcca attcgacagt gaagtcaaaa ccgatttctt tgaaccgtcc gctttcgata 13441 tggggcgcca agtaagcgga gaatcagagg cgctgtacgc tttaagcttc agcggcatga 13501 tcagaaatgg ccggtttgtg ctttcctgct cctacaatga aaaggagttt gaaagagtca 13561 cgattgaaga gcgaatggaa cggtttaaag aaaacctcct gatgttaatc cgccattgca 13621 cggaaaaaga agacaaggaa ttcacaccaa gcgactttag cgccgaagac cttgaaatgg 13681 acgagatggg agatatcttt gacatgcttg aggagaattt aaaataaaac gcaagggaat 13741 tacagaaggc gggagcgaaa catatgagtc aatttagcaa ggatcaggtt caagatatgt 13801 attacctatc gccgatgcag gaagggatgc tttttcatgc catcctgaat cccggccaaa 13861 gcttttacct tgaacaaatc acgatgaaag taaaaggcag cttgaatatc aaatgtcttg 13921 aagaaagcat gaatgtgatc atggaccggt acgatgtatt tcgtaccgtg ttcattcacg 13981 aaaaagtaaa aagacctgtc caagtcgtat tgaaaaaacg gcagttccat atagaagaaa 14041 tcgatctgac acacttaacg ggcagcgagc aaacagccaa aatcaatgag tacaaagaac 14101 aggataagat caggggtttt gatttgacgc gggatattcc gatgcgggca gccattttca 14161 agaaagctga agaaagcttt gaatgggtgt ggagctacca ccacattatt ttggacggat 14221 ggtgcttcgg catcgtcgta caggatctat ttaaggtata caatgctctg cgcgaacaaa 14281 agccgtacag cctgccgccc gtcaaaccgt ataaagacta catcaagtgg cttgaaaagc 14341 aggataaaca agcatcgctc cgctactggc gcgagtactt ggaggacttt gaaggacaaa 14401 cgacgtttgc ggagcaaagg aagaaacaga aggacggcta tgagccgaaa gagctgctct 14461 tttcactgcc ggaggcggaa acaaaggcct ttaccgagct tgcaaaatcg cagcatacca 14521 ctttgagtac ggcgctgcag gcagtctgga gcgtattgat cagccgctat cagcagtctg 14581 gcgatttggc cttcggtaca gttgtttcag ggcgtcccgc ggaaatcaaa ggcgttgaac 14641 atatggtcgg gctgtttatc aacgttgtcc cgagacgtgt gaagctgtct gagggtatca 14701 catttaacgg cttgctcaag cagctgcagg agcaatcgct gcagtctgag ccgcatcaat 14761 atgtgccgct ttatgacatc caaagccagg ccgatcagcc gaaactgatt gaccacatca 14821 ttgtttttga gaactatccg cttcaggatg cgaaaaatga agaaagcagt gaaaacggct 14881 ttgatatggt ggatgttcat gtttttgaga agtcgaatta tgatctcaac ctgatggctt 14941 cccctggaga tgagatgctg attaagcttg cctataatga gaatgtgttt gatgaggcgt 15001 ttatcctgcg cttgaaatct cagcttctca cagcaattca gcagctcatc cagaatccgg 15061 atcagcctgt cagcacgatc aacatcgttg acgacaggga gagagaattt ttgctaaccg 15121 gcttaaaccc gccggctcaa gctcgtgaaa caaagcctct gacggattgg ttcaaggaag 15181 cagtgaacgt caatccggat gcactggcgc ttacgtattt cggccagacc ctgtcttatc 15241 gcgaattaga tgaggaagcg aaccgccttg cacgccggct gcaaaaacac ggtgcgggca 15301 aaggctctgt tgtagcgctg tacacgaagc gctcacttga actggtgatc ggcattctcg 15361 gtgtattaaa ggcgggagca gcctatctgc cggttgatcc gaagctgcca gaggaccgaa 15421 tctcgtatat gctggctgac agtgcggcag cctgtcttct gacgcatcag gagatgaaag 15481 aacaagcggc tgagctgccg tatacaggca caacgctctt cattgatgat caaacacggt 15541 ttgaagaaca ggcaagcgat cctgcaaccg cgattgatcc taatgatccg gcatatatca 15601 tgtacacgtc cggcacaacc ggaaagccaa agggcaatat caccactcat gccaatattc 15661 aaggattggt caagcatgta gactacatgg cattctctga gaaagataca ttcttgtctg 15721 tttcgaatta cgcctttgac gcatttactt ttgatttcta tgcttctatg ctgaatgcgg 15781 cacggctcat tatcgcagat gaacatacgc tgcttgatac agaacggctc acagatctga 15841 tcctgcaaga gaatgtcaat gtcatgtttg cgacaaccgc actatttaat cttctcacag 15901 atgcgggaga ggattggatg aagggactac gctgtatatt attcggcgga gagcgcgcct 15961 cagtgcctca tgtcagaaaa gcgctgcggg tcatggggcc gggcaagctg attaactgct 16021 acgggccgac tgagggaaca gtgtttgcga ctgctcacgt cgtgcatgat ataccggatt 16081 ccatctcctc attgccgatt ggaaagccga tcagcaatgc cagtgtttat attctgaatg 16141 agcaaagcca gctccagcca ttcggggcga tcggtgaact gtgcatcagc ggaatgggcg 16201 tgtcaaaagg atatgtaaat cgtgctgacc tcacgaagga aaagtttatc aagaacccgt 16261 tcaagccggg agaaacgctt taccgcacag gggatttagc acgctggctg ccggatggaa 16321 cgattgaata cgccggccgt attgacgacc aggtcaaaat acgcggacac cggattgagc 16381 ttgaagaaat cgaaaagcag ctgcaggaat acccaggtgt gaaagatgcg gtcgttgtgg 16441 cggaccgcca tgagtctggc gatgcatcaa tcaatgccta ccttgtgaac cgaacgcagc 16501 tttcagctga ggacgtgaag gcgcacctga aaaaacagct tcctgcttat atggtgccgc 16561 aaacctttac cttcttggat gagcttcctt taacgacgaa cgggaaagtc aataaacggc 16621 tgctcccaaa acctgatcag gatcagctgg cggaagaatg gattggaccg cggaacgaga 16681 tggaagaaac aatcgcacaa atctggtctg aggttctcgg cagaaagcaa attggcattc 16741 atgacgattt ctttgcgctc ggagggcatt ccttaaaggc catgaccgcc gcttcccgca 16801 tcaagaaaga gcttgggatt gatcttcctg taaagctttt atttgaagcg ccgacgatcg 16861 ccggcatttc agcgtatgtg aaaaacgggg gccctgatgg cttgcaggat gtaacgataa 16921 tgaatcagga tcaggagcgg atcattttcg cattcccgcc ggttctgggc tatggcctta 16981 tgtaccaaaa tctgtccagc cgcttgccgt catacaagct gtgcgccttt gattttattg 17041 aggaggaaga ccggcttgac cgctatgcgg atttgatcca gaagctgcag ccggaagggc 17101 ctttaacatt gtttggatat tcagcgggat gcagcctggc gtttgaagct gcgaaaaagc 17161 ttgaggaaca aggccgtatt gttcagcgga tcatcatggt cgattcctat aaaaaacaag 17221 gtgtcagtga tctggacgga cgcacggttg aaagtgatgt cgaagcgttg atgaatgtca 17281 atcgggacaa tgaagcgctc aacagcgaag ccgtcaaaca aggcctcaag caaaaaacac 17341 atgcctttta ctcatactac gtcaacctga tcagcacagg ccaggtgaaa gcagatattg 17401 atctgttgac ttccggcgct gattttgaca tgccggaatg gcttgcatca tgggaagaag 17461 ctacaacagg tgcttaccgt atgaaaagag gcttcggaac acacgcagaa atgctgcagg 17521 gcgaaacgct agataggaat gccgggattt tgctcgaatt tcttaataca caaaccgtaa 17581 cggtttcata aatgaagtga tgaaaggagg agacagccaa tgagccaact cttcaaatca 17641 tttgatgcgt cggaaaaaac gcagctcatc tgttttccgt ttgccggcgg ctactcggcg 17701 tcgtttcgcc ctctccatgc ttttttgcag ggggagtgcg agatgctcgc tgccgagccg 17761 ccgggacacg gcacgaatca aacgtcagct attgaggatc tcgaagagct gacggatttg 17821 tacaagcaag aactgaacct tcgccctgat cggccgtttg tgctgttcgg acacagtatg 17881 ggcggaatga tcaccttcag gctggcgcaa aagcttgagc gtgaaggcgt ctttccgcag 17941 gcggttatca tttctgcaat ccagccgcct catattcagc ggaagaaagt gtcccacctg 18001 cctgatgatc agtttctcga tcatattatc caattaggcg gaatgcccgc agagcttgtt 18061 gaaaataagg aggtcatgtc ctttttcctg ccttctttcc gatcagatta ccgggctctt 18121 gaacaatttg agctttacga tctggcccag attcagtcgc ctgttcatgt ctttaacggg 18181 cttgatgata aaaaatgcat acgagatgcg gaaggctgga agaagtgggc aaaagacatc 18241 acattccatc aatttgacgg cgggcacatg ttcctgctgt cacaaacgga agaagtcgca 18301 gaacggattt ttgcgatctt gaatcagcat ccgatcattc aaccgtgatc aaaagcggac 18361 agcttcggct gttccgcttt ttttgtgtag aatgccaact tttgcatggt ataatagtcg 18421 aaatactcaa acaaaggcag gtcgaaacat gcgcacgtct cccaggatga aatggtttgt 18481 attgctgttt acgtttgttt tcgccatcgg aatgaactca ttcagaaatt cctttcaatt 18541 ttttatgctg ccaatggcgg atgccttcca tgccgacagg tcgctgattt cggtttctgt 18601 cagcattttt atgatcacaa ccggcatcgt ccagtttttt gtcggttttt ttatcgaccg 18661 tttcagtgtc agaaaaatta tggcgcttgg agctgtctgc atcagcacaa gctttttggt 18721 gcttccttat tcaccgaatg ttcatgtgtt ttccgccatt tacggtgtgc ttggcggaat 18781 cggctattcc tgcgcggtcg gcgtgacgac ccagtatttc atcagccgtt ggtttgacat 18841 acacaaaggt ctggcgcttg ctattttgac caatgccaac tctgcgggcc tgctgcttct 18901 ctcgcccatt tgggctgcgg ctccgtatca tgcaggctgg cagagcacct atacgatttt 18961 gggaatcgtc atggcggctg ttctgctgcc gctcctcgtc tttgggatga agcacccgcc 19021 gcatgcgcaa gcggagtctg tgaaaaaatc ttatgattgg cgggggtttt ggaacgtgat 19081 gaagcaatcc cgcctcattc atatcctgta cttcggcgtg tttacttgcg gatttacaat 19141 gggaattatt gatgctcacc tcgtcccgat acttaaggat gcgcatgtct ctcatgtcaa 19201 cggaatgatg gccgcgttcg gggcgtttat catcattggc ggattattgg caggctggct 19261 gtccgatctc ctcgggagca gaagcgtcat gctatccatc ttatttttca ttcggctgct 19321 cagcctcatt tgcctgctca ttcccattct cggaattcat cacagcgacc tttggtactt 19381 cgggtttatc ctgttattcg ggctcagtta cacaggcgtg atcccgctga ccgcggcgtc 19441 aatttcggaa agctatcaaa caggattgat cggatcgctg ttaggcatca atttctttat 19501 ccatcaggtt gccggagctc tcagcgtgta tgcgggcggt ttgttttttg acatgactca 19561 tggttatttg ctgattgtcg ctgtgtgcat cgtgtttgtg ggtttatcgg ctgtaataga 19621 gctggtgccg tttttagata aacagaaggc aaaagaaacc caccattcaa tataaaagga 19681 tcagcactgt caatgctgat cctttttaaa tttgagtttt tttgttccgg tatttttaag 19741 gataatctcc ttgaatctgt tcatttcctc tttggaatga aaaaaacgtt ttgggatcgc 19801 aatatattgg ccacttgatg tattgaccct gaagatatta ttatattcga aaacagctgt 19861 gatttcatcc caattgaaaa tgaggtcata ttttttagaa catatacgaa ttccttcttg 19921 gttcagagta tatgttcttt tagatttcat ccgttcgttc ttcttgtatg ctctggaaaa 19981 cttcacatat agaagaagga ggagcagcag tgtaaacaga actgacatca cgataatcaa 20041 catactgttc ataaacaagt taagcgcgtc actgccataa acgatacggg gccatccgtt 20101 aatgaagtta actgcagtaa atatggcgca aaacaacaga aagtaaaagc atgatatttt 20161 tgcgatttga taaaaaaaga tttctcttac atccttaaaa gcgatttctc ctggaagatt 20221 gatactttca ctagcatatt gaatcatacg gtaaacctac acctctaacc atgtttttcc 20281 tttcagtcta gcataatttc tcattttttt gcaggcatac cagggcgctt tgtttttttc 20341 tccagattga tattgctccc caccacgcca atcataatac aaacagcccc ggcaagatga 20401 taccaggcca ggctttcgtt gagaatcaca actcctgcaa tcatcgtcac aatggtagat 20461 acatgattaa aagcgctcat tttaaacgcc tcaattcgcg acagcgtata gttagacaga 20521 aatgaagtga caagtgaaga cagcacgccc aaatacacaa tggcgagaac gaagccgggc 20581 tcccggaacg gcagaaaata agtgccgact gttcccgccg ctccgtgacg cacaagggcg 20641 atggcgttga agacgacaaa gccgatggct gacatgatgt aggtgagctc tgtcagcttg 20701 aaccgctgcg tcatttttct ggcagcagta ttgtacatcg ctgaagacaa agcggacaat 20761 aggatcagca aagacccttt taagctggct gattccacgt caacgccttt catcacaaaa 20821 ataaacatga cgccggcaac ggataaaacc gtgaacccct tttgcgtcca cgttgggcgt 20881 tcctttaaaa cataagcggc aaagaccatc gtgaaaatcg gaatggctgc ctgaataatt 20941 cccgcttcag aggaggacga gtacacaagg ccgaatgcct gaaagctgaa aaataacgcg 21001 ggatacagca gggcgagcgg caaaatggca atgacgtcct ttacgcggat tgatagcttt 21061 acccagccga ataaaatcgg tacagtggcc gcagcaaacg caatggtgaa ccgatgcgcc 21121 aaaatatcaa acggctctgc tgtttgcagt gcgattttta cgaatagaaa ggataaaccg 21181 ataatgaacg aatataaagt agccgctata taagcggggg cttgctgatg tttaaccata 21241 atgggaaggg ctcctttacc tgaattgcag cgccggtcgc tccctttatt gtatggccgc 21301 ggtcagaacg gtacaatgag aaaaacaatg aactgtaccg gtacaaaaca gggggagaag 21361 gcatggagaa atatatgagt ctagtaacga ggatagagga gatgatgcaa agcaccgcct 21421 atcaagaagg agacaggctt ccatctatcc gtcagctgtc cgcccgctac caagtcagca 21481 aaagcacagt gatccgcgcg ctgcaggagc tggaaaagcg ccaccttatc tattctgttc 21541 cgaaaagcgg ctattatatt gtgaaaaaga cagggaaatc aaaaagcggg cagcttggcc 21601 ccatcgactt tgccacatct gcgccggatc cagatgtgtt tccgtatctt gattttcagc 21661 actgtatcaa caaagcgatt gatacataca aaaacgattt gtttatttat gggacgccaa 21721 aggggcttcc atcactcatc cgcgtactcc gaaagctctt ggccactcaa caggtatttg 21781 cggatgaacg gcatattttc attacatcag gtgtccagca ggcgttatcc ttgctttgtg 21841 ccatgccgtt cccaaatggg aaagagaaga tcgccattga acagccgggc taccatttga 21901 tggtcgaaca gcttgagacg gtcgggattc ccgccatcgg ggtgaaacga acagaagaag 21961 ggcttgatat agccaaggtt gagcggttat ttcaaacaga atcgattaaa tttttttata 22021 cgatgccgcg cttccataac ccgcttgggt gctcattgtc agagcgtgat aaacaggagc 22081 ttgtgagact ggcagaagcg tatgatgtct atctcgttga ggatgattac ctcggtgatc 22141 tggaggaaaa taaaaaggca gatccgctgt acgcatatga tctgtcctca catgtcatct 22201 atttgaaaag cttctcgaaa atgatgttcc ccggcctccg cgtgggggcg gctgttttgc 22261 ccgaagcgct gactgacacg ttctatgcgt acaaaaaact gaacgacatc gactgttcga 22321 tgatttctca agcggcattg gagatttacc tgaaaagcgg tatgtatgga aggcataagg 22381 agaaaatcag agattcttat aaagagcggt cgctgaggct acatcaagcc attcgaactc 22441 acaggcagct gggaagcgga cgctttacgt tctccagcgg gcaggcaccc tgtatgcaca 22501 cccatctggt gcttcctcag gatctgcccg cctcaagagt gattcataga ctgaaaaaac 22561 aaggggttct ccttgaggcg atagaccgtc attatttatc agattatccg aaagaaaatc 22621 tattaaaaat caatatttcc tatgtgaaaa cggaagatat tgagcgcggt gtcaagctgt 22681 tgatgagcca tttataaaag ctcttcgtac gagaccattg tgatatcctc ggggaaatca 22741 gggtgtgcgg cgcatacagc cattttgtag ccgggatcga cctcatacgt tttgatatag 22801 catggggaat ggctgtccgg aagctcaatg gatacttgtc cgtcctggtg caggcgcact 22861 gaaaaggaat caagcggaag cgataagcct ttgccttcct gtttgataaa actttctttc 22921 attgaccata gatgataaaa atagtctgtc tgctcgtcct tgtcttttgc taaaaggtcg 22981 ctgtactctg tttttgaaaa gaagcgcttg gcgatctcaa ggctgatcgg tttcgttttt 23041 tcgatatcta tgccgatcgg ctgtgaatca aacgcaccaa tgacccagcg gccggagtga 23101 gaaatgttga aatgagcgtc gggaagatca gggatgcacg gcttcccgta ttcctgcgtg 23161 ctaaagcgga tatcggattt gtccaactga tactgcctgc ttatgactga gcgaacgagc 23221 acatctccca gcagggtgcg gtgagcatct tctttatgat aaaatctccg gcatttctcc 23281 cgtttttcag gtgatatgaa agacatgaac cgttcatttt cttcctgtga aagcgggcgg 23341 tccatataaa ttccgtaaat cttcattcta gatcctccgt ctgcaaaaga ttgtcaaaac 23401 catcctatca tacttccaca agactcatat agaggagaaa ataaaaaaac aaagccaagg 23461 cggctttgtt ttagtgtaca ggcggagatg ctttcacagc ggcggtccgc cttgccacag 23521 cataattcag caactggatt gactggggca atgaaaagcg caaaataagt cctgtgagga 23581 tggcggtcaa aatggtgcca aaaccgatcg gcccgcccat gccccatgct gcaaacaaaa 23641 tggttatttc catgccgttc cgcacccatt gcacattcca gccggttttt tctgtaatca 23701 gcatcatcag tgaatcacgc ggccccgcgc caaggcctgc tgatacataa acaccgacgc 23761 cgtaaccgat cagcaccacg cctagagaga agacgatgat cgagcctgtg taggtcgagg 23821 gggcaggcag aatgaaattg aaaaaatcta taaatacacc aatgagcacc atattcagga 23881 gggccccaat tttcggccaa gctctcgtaa acaatgacgt gaatccgacg atgagcgctc 23941 caataatgat ggaccactgg ccgacggtaa gcccgaagtg ctgaaacagg ctgtaatgaa 24001 atgcatccca cggactaatg ccgagtgctt ttccttctat cgtcagggat acaccaaaag 24061 ccaaaatgat caaaccggca aaataaaatg tccagcgcag aacaagttct tgcttcacgt 24121 gaggtccctt ctttcgtaaa aatcagtcga ttgtcattgt agcacatctg acagaagggc 24181 ggaataggcg aaaggggctc aacaaaaaaa cagggtcgcc gcaggcgccc tgtttcagcg 24241 tgttggcaaa cccttgcatt cgttgtcagg cctgtgcttc ggtgctcacg aatttaacat 24301 tcgctgtgct ccaatgctcg cccttcctag acttcaaagg ttttcaatca cgctgaaaat 24361 cacaaaatcc taaaacgaaa atcgttttag gattttgtca ataatctgaa acagggcgat 24421 ggcgccctgt ttttcttatt acagcgggtt caaaatccgg ttcaagaacc gctgtgtccg 24481 ttcttctttt ggtgcagaga aaatttgctc cggcggtcct tgctccacga taacgccgcc 24541 gtcgatgaag atgacttcat ccgcaacttc ctgcgcgaac ttgatttcgt gggtcacgac 24601 gaccatggtc cagccttcat tggccaagtc cttgataacc ttcagcacct ctccgacaag 24661 ctcgggatca agcgctgagg tcggttcgtc aaacagcatg agctcaggct gaatcgccag 24721 tgcgcgggcg atgccgacgc gctgctgctg gccgccggaa agctggaacg gatataaatc 24781 cattttgtcc ttcaatccga ctttatcaag aagctgaatc gcttcttttc tgacttcctc 24841 tttgttccgt ttttgcacct gaatagggcc ctccatcacg ttttcgaggg ctgtgcggtg 24901 cgggaacagg tgatacgcct gaaacaccat tccggatttt cggcgaagct ttaggatatc 24961 cgcctgtttc acctttttgg agaaatcgat ggagaaatca tcaaatgcaa gctctccgcg 25021 attcgggatc tccagagcgt tcaggcagcg aagcagcgtc gttttccctg aacctgaagg 25081 cccaagtatg gcgatgactt ttcctttttc aatcttcata tctatctttt ttaaaatttc 25141 attttcaccg aatgatttgt ttaatccttt aacggtaagc atactcggaa cctccttatt 25201 tggccacgta gcggtcaaga cgccgttcga tgacatgctg gacgagtgag agcaggaagc 25261 agataatcca ataaataaag gctgcttcaa tatagatcac taaaatttga tcaagattcc 25321 gcgcgccgat ttcctgggct tttctgaaca gctcagcgac cagaatttga gaggcgaggg 25381 atgtatcttt aatcaggctg ataaaggtat tggataatgg cgggatcgac acacgaaacg 25441 cctgcggcaa aatgacgcgg aacagcgttt tttgatgtgt catgccaatt gtgtagccgg 25501 cttcccattg ccctttcggc acggataaaa tagatgcccg aatgatttca gatgcatagg 25561 cgccgacgtt taaagaaaag gcgataactg cgcttggaaa tggatctaat gtgacgttaa 25621 aggccgggaa cagatagaaa atgatgaaca attgaacgag aagaggagtg ccgcgtattg 25681 cggatacgta tacgctgaac acccatctca aaggtctcac tttcgacatt ctggcaagcg 25741 ccgtaatcag cgccaggatc attccgaata taaaggaaag aatcgtaagg ggaatcgtat 25801 agtagattcc ccctgaaagt atcggccaga atgactgctg caccagatcc cacgggatcg 25861 ccgtgccaag cgtcaatgcc ggcagattat ttagaaacat cttcgccgaa ccatttttta 25921 gatattttag aaagagtccc gtcctctttc atttctttta atgctttgtt gacttgatca 25981 acaacctcgc cgcttccttt acggaacgtg aaatatgttg actgaggatc acctgtttca 26041 aacgcgattt tcacgttttt attgccagat gtttttaagt agttcaatac ggcaagctta 26101 tcgttgtatg tcatatcgac gcggccttgc tggatcattt gaagggcctg cgccatacct 26161 tcaacgcctt ctactttagc gccggcattt gtagctaatt tgttgtagtt gcttgtcagt 26221 gattgagctg acgtttttcc ttttacatct gcttcagact taatatcgtt gttgtctttt 26281 ttcgttacga caacggctct tgatgttgtg tatttatctg agaaatcata tttgtcttca 26341 cgatctgttt ttccgacttg gttggcaaca acgtcaaacc gtttggaatt caggccggca 26401 aacatactgt cccactgtgt ttccttaaag tcgactttaa gcccgaggcg ttttgcgact 26461 tctgtgataa cttcgacatc atagccagtc aatttatcag tgtctttgtc gtggtaagtg 26521 aacggctcat atgttccttc cgttccgact gtgagcacac cttttttctt aattgaagcc 26581 caaagatcgc catctttggc attatctttt gactgattgt catttcctgc tccgcaagct 26641 gcaagagctg caatacttac gaccatgaat aaagccaata atgctttttt catcttattc 26701 cccacttttc tggttgattt tattgaaata aaaaaatagc ttacaaatct aaaggataac 26761 ttttttttag tatgagtcaa gtaattggtt ttcataaggc aaaatctttt aaaataaatc 26821 caaaaattgc tgtgccggtt taggcaaata actgtccgtt ctccacatga cagccggtgt 26881 cataatgaag ggattatttt cgatatggac ggtgtgaacg tgatttctca tatgaacggg 26941 aatcattgtg acgggcaaaa tagacgcgcc gaatccggat gacacgaggc tgagcaaagt 27001 tgcagagtcg tggcattcac aaacaatgcg cggctccagg ttcaaacgat gaaattcatt 27061 catgacctga ttatagacgc cttttccgtt gacaggccgc agcaggatca gcggaaatga 27121 aggaatgtcc tccatcttaa tggtgtctcc gcacggatat ccggcttcat ctgaaagcac 27181 gagcacacat ggaatgtcat caagctgttt gaattgtact gtatcacttt tgatcagtgt 27241 tgtcgtgacc gccgcatcga tttgccggct ttccagcagc tccaacagtg tcgcgggttc 27301 attttcccaa atattaaagg tgagatgggg gtatctctct ttgatctgtg ttactttttc 27361 aagcatcaga gccgcgcaat aaatcgttga tcccacggca agtgtgccgg ctacttcctc 27421 cttcagctcc tgtacctcaa tgactgcatc ttcaaaccta tgcagaatct cttttgctct 27481 ttttagaaaa acagctcctt catatgtaag agtcatttgt tttttcttgt tacggtcaaa 27541 cagaacaaca ccaagttcgt cctccagctg tttgagctgc ctgcttaaag gcggctgcgc 27601 catgtgaagc tttttggctg cggacgtaat tttctgttct tgggcaatgg taatgaagta 27661 tcgaagctgg cgaatatcca aaagaaagcg cctccttatc atacctttta ggtattaaat 27721 atagatttaa tagatatttt tcatatggat atatcaggag tatgattgaa atgaaagcag 27781 aattcaagcg taaaggaggg ggcaaagtga aactcgttgt cggaatgaca ggggcaacag 27841 gggccatttt cggggtcagg ctgctacagt ggctgaaggc cgccggagtg gaaacccatc 27901 tcgttgtgtc tccttgggca aacgtcacga tcaaacacga aacaggctat accttacaag 27961 aagtagaaca actggccaca tacacttact cacataagga tcaggcggca gccatttcaa 28021 gcgggtcgtt tgataccgat ggaatgattg ttgcgccgtg cagcatgaaa tctctcgcga 28081 gcattcgcac cggcatggcg gataatctgc tgacacgtgc ggcggatgtc atgctcaagg 28141 agagaaaaaa actcgtcctc ttaacgagag agacgccttt gaaccaaatt catctcgaaa 28201 atatgctagc gcttacgaaa atgggcacaa tcattcttcc tccgatgccg gcattttata 28261 atcagccgag cagcttagag gaaatggttg accatattgt attcagaacg ttggaccaat 28321 tcggcattcg gcttcctgaa gcgaagcgct ggaatgggat tgaaaaacaa aaaggaggag 28381 cttgatcatg gcctatcaag atttcagaga atttctcgca gcccttgaaa aagaaggaca 28441 gctgcttaca gtgaatgaag aggtaaagcc ggaaccggat ttaggggccg ccgcacgggc 28501 agccagcaat cttggcgata aaagccccgc gctcttattt aacaacattt atggctatca 28561 taacgcgcga attgcgatga atgtcatcgg ctcttggcca aaccatgcaa tgatgctggg 28621 catgccgaaa gacacaccgg ttaaagaaca gttttttgaa tttgcgaagc gttatgacca 28681 gtttccgatg ccggtcaaac gtgaggaaac agcgccattt catgaaaatg aaatcacaga 28741 agatatcaat ttgttcgata tactgcctct tttcagaatt aaccaaggtg atggaggcta 28801 ctatttagac aaagcatgtg tcatttcccg tgatcttgaa gaccctgaca acttcggcaa 28861 acaaaatgtc ggcatttaca gaatgcaggt caaaggaaaa gaccgtctcg gcattcagcc 28921 tgttccgcag cacgatattg caatccatct gcgccaagct gaagaacgcg gcatcaacct 28981 tccggtcact attgcgctcg gctgtgagcc ggtcattaca acggcggcat cgactccgct 29041 tctctatgat caatcagaat acgaaatggc aggtgcgatt caaggcgaac catatcgcat 29101 cgtcaaatca aagctgtctg atctggatgt tccgtggggc gctgaagtgg tgcttgaagg 29161 tgagattatt gccggagagc gcgaatatga agggccgttc ggtgaattca caggccatta 29221 ttccggcgga cgcagcatgc cgattatcaa aattaaacgc gtctatcaca gaaacaatcc 29281 gatctttgaa catttatact taggcatgcc ttggacagaa tgcgattaca tgatcggcat 29341 taacacatgc gtgccgcttt atcagcagtt aaaagaagcg tacccgaacg aaattgtggc 29401 agtgaacgcc atgtacacac acggtttaat cgcgattgtt tccacaaaaa cccgctatgg 29461 cggatttgcg aaagcggtcg gcatgcgcgc actcacaacg ccgcacggac tcggctactg 29521 caaaatggtc attgtcgttg atgaggatgt cgatccattc aaccttccgc aggtcatgtg 29581 ggcgctttcg accaaaatgc atccgaaaca cgatgcggtc atcattccgg acttatctgt 29641 cctgccgctt gatccgggat ccaatccatc aggaatcact cacaaaatga ttcttgacgc 29701 cactacaccg gttgcgccgg aaacaagagg ccattattca cagccgcttg attctccgct 29761 aacaacgaaa gaatgggaac aaaaactaat ggacttaatg aataaataag gaaaggatgt 29821 tcgaaatgca tacatgtcct cgatgcgact caaaaaaggg agaagtcatg agcaaatcgc 29881 ctgtagaagg cgcatgggaa gtttatcagt gccaaacatg cttttttaca tggagatcct 29941 gtgaaccgga aagcattaca aatcccgaaa aatacaatcc agcgtttaaa attgatccaa 30001 aggaaacaga aacagcaatt gaagttccgg cggtgccgga acgaaaggct tgatcggcgt 30061 gaacagtatg tcagaccgtc tctttgagct gcttgacggg agatgcctga atgagaagca 30121 gcatgaggcc ttcgttctgc aaacagtatc agaggatggc tggccgcatg ccgctatgat 30181 cagtgcgggt gaaattatcg cgctgagccg aactgatatc cgaatcgctc tgtggaaaaa 30241 cacaatgact tcggccaaca tccttcgcac aggaaaagca cagttcacgg cgtggtggaa 30301 gggagcggcc tattatgtaa agcttgaatg cgcgccttta ccgcctttga aagatgccga 30361 atatgataga gaccgttttt cctgccgcat cgtttcagtg aaggaggacg ttgcgaaata 30421 cgctgatttg acttcaggtg tccgtataca gcttcacagc cctgaagagg tgctgggcag 30481 atgggaaaag accctggaag atttaaagcg gtaatatcga tagcctgacg ccatgcgtca 30541 ggcttttttt atataatgaa aacaaagggg gcgtgagaaa tggaacgtgc ggggatctgt 30601 cactcggacg gctttgattt agcttatcga attgagggcg agggcgcacc catccttgtg 30661 atcgggagtg cggtttacta tccgcgcctt ttttcctcag atatcaaaca gaaatatcaa 30721 tgggtctttg tcgaccatag gggatttgct aagcctaagc gggagcttcg tgcggaggat 30781 tcgaggcttg atgccgtctt ggctgatatc gaaaggatga gaacatttct tcagcttgag 30841 gatgttacta tcctgggaca ttccgggcac gcttttatgg ctttagagta tgccaggaca 30901 tatcccaaac aagttcggaa ggtggcgctc ttcaatactg cgcctgataa cagtgaagaa 30961 agacagcgaa aaagcgaatc atttttcatg gaaacagcca gccttgagag aaagaaacga 31021 tttgaaaaag acatcgcgaa tttgccgcag gacatcgaca aagatcctga aaggcgcttt 31081 gtgcacatgt gtattcgcgc tgaagcgaaa agcttttatc aagagcggcc gcatgctgct 31141 gccttatggg acggtgtatt cacgaatatg ccgatcatgg atgaattatg gggcaataca 31201 tttgcccaga ttgatcttat tcagcggtta gctgatgttc gtatgccggt gtatatcgga 31261 ttagggagat atgattattt ggttgcgccc gttgcgctat gggatgcagt tgacggttta 31321 tattcccatg tggataaggt tatttttgaa aggagcggcc atcagccgat gctggaagaa 31381 ccggaagcct ttgatcaaag cttcagcaaa tggctggatc aataaaaaaa cagcccgcag 31441 atcaaaatcc gcgggctgtt tctgattata agaccccttt catcgcacgt ttgataaccg 31501 gcgagagcag caggagaatg ccgccaagaa cgatagaaat caaaccgatg gtgccgaagt 31561 acattgtttc aggaatttta tcaaacaatc cggctacttg ggcattgatc gcttgggctg 31621 ctgcgttcgt cagaaaccac atactcattg tctgtgcaga gaaggcagct ggggccagtt 31681 tcgttgtcac ggataaaccg actggagaca ggcacagctc tccaagcacg acaagcagga 31741 agctgagaac gagccaaagc gggcttacga gtgcttcttt tccttgcata gcagggaata 31801 ccataatgat aaatgacaat ccggccaaaa taattccgat tgagaattta actggtgtag 31861 aaggctggcg tttgccaagc ttcatccaga gccatgcgaa tattggcgca aaaatgacaa 31921 caaacaatgg atttaatgat tggaaccaag atgactgaag ttcgaatccg cccaatgaaa 31981 gtcttatgcg ttcatcagcg tataccgcaa gaatggtcgc tccctgttcc tgaatggccc 32041 agaacatgac agcaccgata aacaaaggaa tgtaagcggc aagacgggat ttttctgtgc 32101 tgtccgcttt tttgcttgta aacatgatga tgaaataaat gacaggaatc aaaataccga 32161 gaatacttac aaggtcgata aaacgattga tcgtcagcac gcctgtttgt acagagatca 32221 tcactgcgat cgccacgatg ataacaccga ttccggtgcc aatcgcagat tttttagaca 32281 gcggattcgg cacattggaa cctgcaagcc cgaggttttt ctttcttgtc aaagcaaaaa 32341 cgataagtcc gagaagcatt ccgaccgcgg cagctccgaa gccgagatga tagttgtact 32401 tctgtccgag tgttccgaca attaacggtg caagtaaacc accgaggtta atccccatgt 32461 agaaaatact gaaacctgag tcgcggcgcg ggtcttcttt cgtgtaaaga tccccaacca 32521 cgcttgaaac gtttggtttt aataagcctg ttccgacaat aataagcacc atgctgatat 32581 agaatgcgat cgcgctgccc ggataggcga gtgcaatgtg gccgaacata atgaatatgc 32641 cgccgtaaaa aacggtgttt gcggtaccga atacccggtc agcgagccat ccgccaataa 32701 tggtggacat gtatacgagt gatccgtaaa tcgacataat ggcaaccgca gtgcccttgt 32761 caaagccgag ccctccgttt accgtctctg tatacaaata gtaaagtaag attgctctca 32821 ttccatagta agagaaacgc tcccaaaatt cggtgaaaaa tagtgtaaat agtcctcgcg 32881 ggtgaccaaa gaaccctttt tgcgggacgc ttttaatgat actttcgtta tcaatcgaag 32941 ccatgtcagc caaacccttt ctaaaaaaag tgtattataa aaatcatatt cttatataat 33001 acttgtgtca atataattta tactcatttc aaatagttcc ataatggaaa aattataaat 33061 acctaaaaat agtgattttc tcctaatttt tatactcttt atcgtgagat tttcttacac 33121 aactattcct ttatattttt ttaataaaat tttagagaaa tgtacaagca gatcgggcct 33181 ttgtgagtaa catgatagta atcatagaga aggaggctcg caattggctg aattcatatt 33241 aaatgcagcg gatttcggtg ttcctggaga tggtaaaacg gattcgacag aacggattaa 33301 tcagtgcctc agtacagctg tttcgaaagg ctatcatact gtctggtttc caaagggaac 33361 atatttaata gacgcaacgc ttggcggaga tcttaatcag aggtttcgaa acgcggggat 33421 cattgttccc ggcaaccttg agattatgat ggaccccgaa tgtatcatga aagtgatacc 33481 gaatagttcg tggggttatt ccgcatttta tgtaggcaag caagagaata taaccatttc 33541 cgggggacaa attatcggcg aacgggatga gcatacgtat gcctcggcag ggataaggtc 33601 aacccatgaa tggggctttg gcatatgtat tgaaggatgc tcgaatgttg tcattgatga 33661 tgtgaaaatt tccgatttta ccggcgatgg gatcatagtc agcccaaggg gattaaagac 33721 caatcaagat tatcgaacgt cagagcaaat tatcatccgc cgctgtgagg ttcggcggtc 33781 gaggagaaat aacatttcca ttaccggatg tgacatggtc acggtggagg catgcttgat 33841 tgaagatgcc ggaacgggga atggaacagc gccgaaattc ggaattgaca ttgaaggata 33901 tggcgaaggt gatgttgatt atgaggaacc gattaatgta tcaattcgca ataaccactt 33961 tgttggaaac gtttcaagtt ctgtgaccaa ttttaacggg tatggcattt taatagaagg 34021 aaatcactca gacaatacaa tcagctacgg atatgggacg caaacagtga tcaagggaaa 34081 tatactgagg cgccctgaag acgcggcggc tgcgccaaga gtcgggataa ccggactcgg 34141 tgtatcacaa ggaaaagaga ccagtgatgc agtgatcgct ggcaacctca ttaccggatt 34201 ttcaacagga attgatgtca ggggaaagag cgttcttgtg acgaacaaca aaatcagcaa 34261 ctttgaaaat acagggatat tggtttatca gtcctccgac gtaaaggtag acggaaacca 34321 aattcaaaac ggactgtctg aaacaaggcg cagcatcggt cttcgtgcag tgctttcaga 34381 tgacaccgct tttctgaata actgtctcat tcaagtcgtt gacggtgtga gcgtttcggg 34441 cggaaacatg atcattaaag ataatctcct gagaaaattc agccgaggca tttggattgc 34501 tcaaggggat gcggtgattg aagggaatac actgaatcct ggcgcgtttg aagcagtgcc 34561 ggaatcatat tctgtttccg ttacaaacaa tgccggcgct atcatcaaaa acaatacatt 34621 taaagagttt aaaaattacc ccatttactg ctccacaagt gcaaaaacct caattatcgg 34681 caaccactta gagagatctc cgcttttggt caccatctat atcagcgccg gtgtgcatga 34741 gatttttgat aataccattt cagtcaacag aacagccggg aatccgattg tgatttatct 34801 caatggctct gcaggctcaa tcatcgcagg aaacaccatc aataacctct ccgcgggcac 34861 tgctacagct attcaaacaa acacgtcaac caattccaaa atcatcggca accgcatttt 34921 taaagggact atcaacaaac acagcagtga tgcaatagac ggcaatatta tcgtctgaaa 34981 aaagcgcccc ctctaggggt tctttttttt cgatttatag atcacgtaca tttctctcac 35041 aagtactaac acaaaaaata aaagcacgac ccattccgca aatgttgtca tcttaaagct 35101 ggacatattg ttataaatgg cttttgttaa actgaaccct tgaagcatgt ccatcaatac 35161 agaaatagct aataaacaaa ttaatataac tcctgtcacg cccaatatct tcatgcttca 35221 tcatcctccg cttttagtgt ctatcgttgg cggagaagtt ataccgcatc taaacctaat 35281 gcataatctc aattttaaaa ggaagaatat gagaaaacga caaggaaagg tatttgtgta 35341 tgcctttatt ttctaagcga aagaacaata caagttcgaa agacaagcgc aatacagaag 35401 aaaagaatca ggaacagaag caagaaaaag aaaggccggt tctcatttct ccaagtttgg 35461 caaagaatat agcggaaacg aaaaaggaag tcggaagcag ctctgacgtc atcattcgcg 35521 agattaaaat cggggagcag gatcatgtcc acctggctgt tatctatatt gctgggctgg 35581 tcgataataa cacgatccat gagtcattaa ttgacccatt ggtacaggat gagtctatcc 35641 agaatactca tgcgatccag caaattcttg aaaaaacgct cccgctgggc ggggtgaaag 35701 cggaaaagag ctgggacaag cttttttccg agttaatgct cggcaatgcg ctcatttttg 35761 ctgatggcta tgatgaagct ttgatttgca gcactcaagg gggagagcag cgctccatcc 35821 aagagccgag cacccaggtg tcattccgcg gcccgcgcca agggtttaca gagtctctgc 35881 aaaccaatat ttccatgatc cggcgataca ttaaaaatcc gaatttatgg gttgaaaaaa 35941 tgaaaaaagg ttctgttacg aatacggata tcgctctcat gtacattcaa ggaatatgtg 36001 atgaaaaggt gctgaaggaa gtgaagcagc gcctggaaaa aatagatatt gacagtattt 36061 tggaatctgg atatattgag cagctgattg aagatgaaac ctttacgacg tttccgacta 36121 tgtatcatac agaacgccct gatgttgtag cgggtaatct gttagaagga agattcgcga 36181 ttattgtcga cggaacaccg tttgtgctta ttgccccggc cttatttgtc cagttttttc 36241 agtctgttga ggattattat tcgcgttttg acattgcgac aagcataaga attcttcgtg 36301 ttttagtctt tttcatttcg cttgtggctc cggctgtata cgtggcagcc acgacgtttc 36361 atcaagaaat gataccgact cagctgttag tggtcattgc ggcccagcgg gaaattgtcc 36421 cgtttccggc tgttgtggag gcgctgacga tggaggttgc ttttgagatt ctgagggaag 36481 cgggagtcag gctgccccgg gttgtcggct cggcagtgtc aatcgtaggc gcgctcgtaa 36541 tcggccaggc tgccgtacaa gctggcatcg tctctccggc aatggtgatt atcgtggcac 36601 tcaccgcgat tgcgagcttt gcaacaccgg cgtttgcaat ggcgatttca gctcggctta 36661 ttcggtttat ctttattatt gcctcagctg ttatgggttt ttacgggctg attttaggga 36721 tcattatgat gtttgtccac ttatgcagtc ttcgttcatt cggcgttcca tatatgtcgc 36781 cgcttgcacc cttttcttca caaggcgtaa aggacgcgct tttcagggtt ccgtggtggg 36841 ccgatgaaaa aaggccggaa tcggtcagta aggaagataa ggtgcggcag gggcaagatc 36901 aacgcccaga gccggccgct tcacgaggaa tggtgaacaa agatttggaa gaaggggatc 36961 agaatggtac gtaaatgtct attagccgtt ctcatgcttt tgagcgtcat tgtgctgccc 37021 ggctgctggg ataagcggga gctgacggat cttgcgatta tctcggcgat tggcatcgat 37081 cggacaaacg acagcaacta cgtgctgcat cttcaaatta tcaatccagg aaatgttgcc 37141 ggcggccttc agggaggcgg tgctggagac aggccgcctg tatctgtcta ttcgattgaa 37201 ggtaacaata taacggaagc gctcagaaaa gcctccatga aggtatcacg gcggctttat 37261 tttgcccata ccaatctagt cgtgatcaat gaaaagctgg caaaagaaga aggtttggat 37321 tttgtattag ataatcttga ccgggacaca gaattcagga caacagcaac attcgtcgtt 37381 gcccataaaa caaaagcaga aaatatcgta aaaatcctga cgccgattga taaaattccg 37441 tcaaataaag tcaataaaac actcgatttc acggaggcgc aatacgggcg ggtggtcaaa 37501 accaatattc aggacgtttt gaaaacactt gccgccaaca ctatggcacc ggttatcccg 37561 ggatatatga tgattggtga cgataaaaaa g //