LOCUS       c00041_gnlPro..        15578 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EELJGKON_43.
ACCESSION   c00041_gnlPro..
VERSION     c00041_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 07:57:15
            Original ID  :: gnl|Prokka|EELJGKON_43
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 188280
            Orig. end    :: 203858
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15578
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[198280:201525]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13245
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15578
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15578
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             1121..1645
                     /locus_tag="ctg41_172"
                     /transl_table=11
                     /translation="MTTIAAVRKDGVTALAGDGQVTLGEKVIMKGNAQKVRRIYHDQVV
                     IGFAGGVADAFTLQDWFEKKLEHYAGNLRRSAVALAQDWRKDSTLQKLEAMMIVMDEHD
                     LLLVSGSGEVIDPDEDVVAIGSGGNFAQAAAIAMLRHAPDMTPADIAKEAVNIAGNIDI
                     FTNHNVIVESF"
     CDS             1689..3098
                     /locus_tag="ctg41_173"
                     /transl_table=11
                     /translation="MAEVQTPKQIVEKLDQYVIGQDDAKRAVAVALYNRYRRMQLSPKM
                     QEEITPKNLLMIGPTGVGKTEIARRLAKIVEAPFVKVEATKFTEVGYVGRDVESMVRDL
                     AETAVAMEEEKQFSKVRIRAEKEANKRLVKILVPAIRKEKNTNPMAEMMSMLQGMQNGK
                     MPAGDDADAGGEVTDDIRNKRLSVAEQLEKGLLEDHEITVAVNDEKKGGGMGDMYGQMG
                     IDLSDTIGALMPKKKVERTMTVKEAREIFIKEESDKLVNHADIYHDAIQSAENNGIIFI
                     DEIDKIAAGNKHNSGEVSREGVQRDILPIVEGSQINTKYGPINTDHILFIGSGAFAEAK
                     PSDLIAELQGRFPIRVELKDLTEKDFVRILTEPDNALIKQYIALIGADGVKITFTKEAV
                     DRIAEIATQVNHDTDNIGARRLATILEKLLEDVLYEGPDMAMGSVTVTQQYVDDKIGHI
                     AADSNMTRYIL"
     CDS             3134..4012
                     /locus_tag="ctg41_174"
                     /transl_table=11
                     /translation="MVTIANDFLTVKISRHGAELTSIKDNLTGRERLWQADPAVWGRHA
                     PVLFPIVGALADNQYHYAGKTYHMGQHGFARDRDFTVLSATPFKASFVLKDDDKTRAMY
                     PFAFRLIITFALENNNLHVTYHVDNPDKSEPLFFSIGGHPGFKVPMTPDTQFSDYYLNF
                     KPRKSLVQIPLVAGEGIDYTHRTLAATDANLALTHETFDHDALIFALLGKTTFNLVSDK
                     TKHGVSVTMTDTPYLGVWSPYPTTGDFVCIEPWWGIADTIGSTGDLTRKLGINRLEPGT
                     AFEKGYMISIF"
     CDS             complement(4094..4717)
                     /locus_tag="ctg41_175"
                     /transl_table=11
                     /translation="LILVLCFILAYFIGAIPFGVVIGKLFYHTDIRKGGSHNIGTTNAY
                     RMLGPVGGSIVLVLDILKGTLAASLPILFGIEHHWLVLIVGLAAVFGHTFSIYIRFKGG
                     KAVATSAGILLAYNPPFFVIAFAIWFSLILLTSMVSVASTLGMVLITAWSLVYHDWLLT
                     TVACGLLVVFLIKHRANFKRIKAGDENMVPFGLGQYLRQHRGRS"
     CDS             5286..7298
                     /locus_tag="ctg41_176"
                     /transl_table=11
                     /translation="MDKATQAYNDSSIQVLHGLEAVRKRPGMYIGSTDGRGLHHLVYEI
                     VDNSVDEALAGFGDEINVTIHADNSVTVQDHGRGMPTGMHPSGKPTIEVILTVLHAGGK
                     FNQNSYKTSGGLHGVGSSVVNALSESLTVRVVRDKRAFEEHFINGGHPDGTLQKLGKVN
                     EPNGTTITFKPDPTIFQTTVFSYDTLAERLRESAFLLKNITINLTDERTGKHDSYHYPD
                     GLVSFVKYLNEGKDALSQVINFEGKKDGIVVDFAGQYNDGYSENLISFVNNVRTGDGGT
                     HEIGLRSGMTRAFNEFARKVGLLKERDKNLEGSDVREGFAGILSVRIPEEILQFEGQTK
                     GKLGTPQARTVVDGIVYDKLSTFLMENGEESQELVRKAVKARDAREAARKARDDSRTGR
                     KRKKDQGLLSGKLTPAQTKNPKRNELYLVEGDSAGGSAKQGRDRKFQAILPLRGKVLNT
                     QKAKLQDIVKNEEINTMIYTIGAGVGADFDLQQANYDKIIIMTDADTDGAHIQILLLTF
                     FYRYMRPLIDAGRIYIALPPLYRLQKGAGAKTKISYAWTDEELAKETKAMGKGYTLTRF
                     KGLGEMNADQLWETTMNPETRTLIRVRIDDAQLAERRVTTLMGDRVEPRREWIEHNVKF
                     DMDDDGSILETPTANHEKLQFGAKQIVKQLDKKGK"
     CDS             7305..9749
                     /locus_tag="ctg41_177"
                     /transl_table=11
                     /translation="LANQIQELTLEEVMGDRFGRYSKYIIQERALPDVRDGLKPVQRRI
                     LFAMNQDGNTYDKGFRKSAKSVGNVMGNYHPHGDSSIYEAMVRLSQDWKLRAPLIQMHG
                     NNGSMDGDPPAAMRYTEARLSKISKEMLADIDKETVDMVLNFDDTAQEPTVLPAGFPNL
                     LVNGATGISAGYATEIPPHNLREVINAVLYLLKHPTADLDTLMQYVKGPDFPTGGIIQG
                     LDGIKQAYETGRGKIVVRSRTHIETIRGGREKIVVTEIPYDVNKAQMIKKIDELRINKK
                     VDGIAEVRDESDRFGLSVVIELKKEADAHGILNYLFKNTDLQIAYNFNMVAIADMQPKL
                     LGLKAMLEAYVEHRRDVVTRRTRFDLNKAAARQHIVEGLIKMLSILDQVIAAIRASKDK
                     GDAKRNLVKKFDFSEAQAEAIVSLQLYRLTNTDITALQKEAAQLAKAIAEYQDILARPA
                     ARDRVIEGELKRIAEEYGDDRRSSIQAKIETLEVATTVTVADETVMVQVSRDGYVKRSS
                     LRSYQAVDPADNGLKANDLAIFTGELSTLQHLYIVTNAGNVIYRPVHEISDARWKDTGE
                     HLSQTVGLGTDEKVLAVFAFDQLDGAGSFVLGSSDGYIKQTALSDLQPQRTYKSKPMMA
                     MKLKDPAAIVTNAYFTTDQQQDVFVVSRHAYGLTFPLSDVSTVGARATGVKSMDLKPDD
                     EVVNFILVKDPTTAKVGILTQRGAFKKMALSEVGEMSRARRGLLVLRELKRDPHRIVAM
                     MSVDDATRLNVLTDTGKVTTLNPAQHPAGDRYSNGSFVIDTDVLGKPVFVQTKEEPADQ
                     VE"
     CDS             10001..12262
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg41_178"
                     /sec_met_domain="Gly_radical (E-value: 7.2e-41, bitscore:
                     132.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 3.1e-243, bitscore:
                     802.0, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQLDEIKVPNYWEGFNGGDWQEEINVRDFIEHNLNQYDGDESFL
                     AGPTEATTVLNNQVLNLKKQERANGGVLDADNNIPSTITSHGPGYLNKDLEKIVGVQTD
                     KPFKRAFMPFGGIRMAEDALESYGFKTDPQEHKIFNEYRKTHNQGVFDAYTPDMRKARH
                     YKIVTGLPDAYGRGRIVSDFPRIAVYGIDRLMAEKFKDYNLTGDGEMTDDVIKLREEIN
                     EQYRALNDMKKMAKEYGYDISRPAANAQEAVQWIYFGYLAAVKTQNGAAMSVGRIDTVI
                     DAYIQRDMRLGKLNEEQAQELIDHLVMKLRMVRFIRTEEYNSLFSGDPIWATLSLAGMG
                     NDGRHHVTKTAFRFLKTLDNMGAAPEPNITLLWSERLPEGFKRYATEVSIQSSTIQYEN
                     DDLMRNEWGTDYYGIACCVSAQPIADGVQYFGARANLAKTVLYAINGGKDEIQEAQVGP
                     EYAPITSDYIDYKEFMNKFDKMMDWLADTYVNALNVIHYMHDKYYYEAAQLALKDTQLN
                     RTFATGISGLSHAVDSISAIKYGHVKAIRDENGVAVDFVADNDDYPRYGNNDDRADDIA
                     KWLVKTFYNKMNTHHLYRGAKLSTSVLTITSNVVYGKNTGTTPNGRQKGEPFSPGANPA
                     YGAEKNGALASLMSTAKIPYHYATDGISNTFGVTPNTLGHDDETRKDTLVHMVDGYMEN
                     SGMHLNINVFNKETLIDAQKHPEEYPTLTVRVSGYCVYFADLTKEQQDDVIARTFFEEM
                     "
     CDS             12394..13245
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 65.2;
                     E-value: 2.4e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg41_179"
                     /sec_met_domain="Radical_SAM (E-value: 2.4e-24, bitscore:
                     80.1, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLIDQSQSPLNILEQVGQDHDGPIKGYVHSVESFGSVDGPGIRF
                     VVFMQGCRMRCQYCHNPDTWNIGVGEEMTADQILADAQRYKAFWGDQGGITCSGGESLV
                     QIDFILELFTKAKALGISTCLDTSGGPFTRDQPWFGQFEKLMAVTDISLVDIKHIDSAE
                     HKKLTGFPNENILDMVQYMSAHADDMWIRHVLVPERTDFDPYLKRLGDYIATLDKNVVQ
                     KVEILPYHTLGVKKYHELGITYPLEGIEPPSADRVKNAENLLHVKDYTGWQSWRPKPVA
                     SN"
     CDS             13370..14338
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     60.8; E-value: 3.2e-19)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg41_180"
                     /sec_met_domain="LysR_substrate (E-value: 2.7e-26,
                     bitscore: 85.7, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 9.3e-19, bitscore: 60.8,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTKQERIFSSKTLTYFLQLAETMNYTQAAQLLGITQPALTQQIK
                     KLERTVGAPLFYSVGKKLHLSDAGQTMLKSTHEIYEILNQTTDEIQQTTSATVGKINIG
                     LLSSIEDSAFIAFIAHYYQLNPEVEVTLRMMTRHEIWESLENNQIDLAIMNLPDETIKN
                     WKPYASKKIIDEQLLFLHHDDALANRKRIHFKDTLAEPWATYPDDYFLGQLLREAYKNQ
                     MVDFPHVVAHFTTPYQLTQFVNLSGVNTALPTSFVRARADQIKAYAIAFDPAIRFEISF
                     VYRKEKADIPRISNFFQTFDDYLKEKDYLSRVSENRVKLDK"
     CDS             14368..15300
                     /locus_tag="ctg41_181"
                     /transl_table=11
                     /translation="MTTLIFGHQNPDTDAITSAMSWAEFQKQAGNTDVEAVALGEPNDE
                     TKFVFDHFKVQAPRVIKTAANETDHVMLVDHNEFQQSVSDIEDVTIDSVVDHHRIANFH
                     TAAPLFYRAEPVGSTNTVIFEMFQEYGFKISPTLAGLMASGLISDTLLLKSPTATDKDK
                     KILPEMAKIAGIDLQSYGLAMLKAGTNLAAKSDMDIIEGDAKSFTMGGKSIRIGQVNTV
                     DLNDIYARQDELVSAMTKEAQAKGYDDFLLIATDILDSNSTGFAVGADRDKIASAFNEQ
                     FDKDARLALPGVVSRKKQVVPPMQSTFEG"
ORIGIN
        1 gagtatcttg aagttgaacg gcagtattca ccggaaacag tgacggctta tttgagtgat
       61 cttcaagaat ttcaggcgtt tctcaaggcc aacggcgggt ttactgactt tcggcatgtg
      121 gatgatttag acgttcaaac ttatttgact gatcttaaca aacaggattt ggcacggaca
      181 tcgattgccc gaaaaatcag tagtttgcga agcttttacc gttatttgac acgaattgat
      241 gtcgtcaaac gcaacccatt tgagctggtt gaattaaaaa agcagcatca tcatttacct
      301 caatttttct atgaagccga gattcaggaa ctgttcaaga cagttgctgg caaaaccccg
      361 ctggatcaac gtaatcgcgc tttgttggaa gttttgtatg gcaccggtat tcgagtttcc
      421 gagtgtgcca agctgacatt gaatcaggtc gatttcaata cggcattact gttgattcat
      481 ggtaaaggca acaaagatag gtatgtgccc tttggacagt acgctcagca agcactacga
      541 acttatttaa aagatggtcg acaagttttg atggctaaaa gtcaggcaca gcatcgatat
      601 gtattcgtga accagtatgg gcgcccgatt acctcgcgcg gcattgaata tattttggat
      661 cagctcatca agcagacgac gctaacagct aacattcatc cccacatgct gcggcatagt
      721 tttgcaaccc atatgctgga tcatggtgct gacctgcgaa ctgttcaaga gctactgggt
      781 catgcaagtt tatcaaccac acaaatctac acgcatgtca ccatggcaca tttaaaaaat
      841 gagtatatga aatattatcc gaagcataat taagactaaa gcatgatgca aaagcggtct
      901 gagtttttta agctaagaac attggcgata acagattaat cggtacttta gctgttttta
      961 tccgacgaga tacgcagata acgcgctcgc agtcgcagaa acctacacat aatgacctgc
     1021 aagcctaaat ggctgaattt tggctattta ggcttgcagc ccacttatgc tccggtttct
     1081 aagcgcttct gctcgcgctc acttaaaaag gagcatgact atgacaacaa ttgcagcagt
     1141 gagaaaagat ggtgtgaccg ctttggccgg tgacggtcag gtaacccttg gcgaaaaggt
     1201 catcatgaaa ggcaacgcgc agaaagttcg ccggatctat catgatcaag tcgtcatcgg
     1261 atttgccggc ggggtggcag atgctttcac cctgcaagac tggtttgaaa agaagctgga
     1321 gcattatgcg ggcaacttgc gacgttccgc agttgcgctg gctcaagatt ggcgcaagga
     1381 ttcgaccttg cagaaacttg aggccatgat gatcgtgatg gatgagcatg acctgttact
     1441 tgtatccggg tctggcgaag tgatagatcc agatgaagac gtggtagcga tcggctccgg
     1501 cggcaacttt gcgcaagccg cggcaatcgc gatgctgcgg catgccccag atatgacacc
     1561 agctgacatt gccaaagaag cagtgaatat cgcagggaat atcgatattt tcacaaacca
     1621 caatgttatt gtcgaaagct tttagtttgt aaccgtcggc aattacattg acctacagga
     1681 ggcttatgat ggcagaagta caaaccccaa aacagatcgt tgaaaaactc gatcaatatg
     1741 tcattggaca agatgatgca aaacgggccg tcgcggttgc cttgtataac cgttatcggc
     1801 gaatgcaatt atcgccaaaa atgcaagaag agattacccc gaaaaactta ctgatgatcg
     1861 gaccaaccgg tgtcgggaaa accgaaattg cacgacgact ggcgaaaata gttgaggcgc
     1921 catttgtgaa ggtggaagcg actaagttta cggaagttgg ctacgttggc cgtgacgtcg
     1981 aatccatggt ccgagatctt gccgaaactg ccgttgccat ggaagaagag aagcaatttt
     2041 caaaggttcg catacgtgcc gaaaaagaag ccaataagcg tttggttaaa attttagtgc
     2101 cggccattcg taaggaaaag aataccaatc cgatggccga gatgatgagc atgttgcaag
     2161 ggatgcaaaa tggcaaaatg ccagctggcg atgatgcaga cgcaggcggc gaagtgaccg
     2221 atgatattcg caataagcgt ttgagcgtgg cagagcaact ggaaaaagga ttacttgaag
     2281 atcatgaaat caccgttgct gtcaatgatg agaaaaaagg cggtggcatg ggtgacatgt
     2341 acggtcagat gggcattgat ctaagcgaca ccattggcgc tttaatgcct aagaaaaagg
     2401 ttgagcggac catgaccgtc aaagaagctc gcgaaatctt catcaaagag gaatctgaca
     2461 aactggtcaa tcatgccgac atctatcacg acgccattca aagtgccgag aataacggga
     2521 tcattttcat cgacgaaatc gataaaattg ctgcaggaaa caagcataat agcggcgaag
     2581 tttcgcgtga aggtgtgcag cgagatattt taccgattgt agaaggatcg cagattaaca
     2641 ctaagtatgg tcctatcaat acggatcaca tcttgttcat tggctcaggt gcgtttgccg
     2701 aggctaagcc tagtgatttg attgctgaac ttcaagggcg ttttccaatt cgggttgaat
     2761 tgaaggactt aaccgaaaaa gactttgtgc ggatcttgac cgagccagac aatgctttga
     2821 tcaagcagta tatcgccttg attggtgcag atggcgtgaa gattaccttc acgaaggaag
     2881 cggttgatcg aattgcagag attgcgactc aggtcaacca cgacactgat aatattggag
     2941 cgcggcgact ggcgaccatt cttgaaaaac tgcttgaaga cgtactttat gaaggtccag
     3001 atatggcgat gggcagtgtg accgtcaccc agcaatatgt ggatgacaag attggccata
     3061 ttgcggctga ttcaaacatg acgcggtata ttttgtagtt aacaataatg ttgtaggtaa
     3121 aggatgagga tgtatggtaa cgattgcaaa tgactttttg acagttaaaa tcagtcggca
     3181 tggtgctgaa ctgaccagta tcaaagataa cctgacaggc agggagcgtc tgtggcaagc
     3241 agatcctgcg gtgtggggtc gccacgcccc ggtcttgttc ccgattgttg gggcgctggc
     3301 tgacaatcaa tatcattacg caggcaagac ttaccacatg ggccagcacg gttttgcccg
     3361 tgatcgtgat ttcacggtgc tctctgcgac accgtttaaa gcgagcttcg ttctgaagga
     3421 tgatgacaaa acgcgggcga tgtacccgtt cgcttttcgt ttaatcatca cgtttgcact
     3481 agaaaataac aatctacatg tcacgtatca cgttgacaat ccggacaaaa gtgagccact
     3541 gttctttagc atcggcggcc atccgggctt caaggtccca atgacgccgg atactcaatt
     3601 ctccgattat tatttgaact tcaaaccgcg taagtcgctt gttcagattc cgttggttgc
     3661 tggtgaaggc attgattaca cgcaccggac cttggctgca actgatgcca atttggcctt
     3721 aacgcacgaa acatttgatc atgatgcttt aattttcgcg ttgcttggta agacaacctt
     3781 caacttggtt tctgacaaga cgaaacatgg tgtcagcgtt accatgaccg ataccccata
     3841 tctgggcgtt tggagtccgt atccaaccac tggcgacttt gtctgcatcg aaccttggtg
     3901 gggcatcgcc gacacgattg gcagcactgg cgacctgacg cgcaaactcg ggatcaatcg
     3961 acttgaacct ggcacggcat ttgagaaggg ttacatgatc agcattttct aaggtgtcat
     4021 cagtttgtcg attaggtaca tgaaaaaaag acatccagtt tcggatgtct ttttggttgc
     4081 cattaaaagg tgactaagag cggccccggt gttgacgaag atattggcct aagccaaagg
     4141 gcaccatatt ttcatctccg gccttgatgc gtttgaagtt tgcccgatgt ttgatcaaaa
     4201 agacaaccag caacccgcag gcaacagttg tcagcaacca atcatggtaa accagcgacc
     4261 aagctgtgat caacaccata cccagtgtgc tggcaacgct gaccatggac gtcagcaaga
     4321 tcaaactgaa ccagatggca aatgcaatga caaaaaatgg cggattatat gcaagtaaaa
     4381 tgccagcgct agttgccacc gccttaccgc ctttaaagcg aatgtagatc gaaaatgtat
     4441 gaccgaatac ggccgctaaa cccacgatca gcaccagcca atgatgctcg atgccaaaga
     4501 gaatgggtaa gctggcagcc aacgtgcctt ttaagatatc cagcaccaag acaattgagc
     4561 cgccgactgg ccctaacatg cgataagcat ttgtggtgcc aatattgtga ctcccgcctt
     4621 tgcggatatc cgtgtgataa aagagtttac caatgaccac accaaacggg atggcgccta
     4681 tgaaatacgc gagtataaaa caaagcacaa gtatcaaatg tgcccctcct ctcaaactag
     4741 aaactatttt agcatttttg acttttgagt gatacgtcag tagaataaaa cgaacgtaca
     4801 ttcgaataaa acctgtgaag cgggttgtgg cgcgatttgg tgccgtcttg tgcaaggatc
     4861 atggcggggc acagcgtaga tatggtgcca gcgggcgatg aatttcacgt caagaagtca
     4921 tagttatgtg ccatgcttag ggaagtgcgg ttttctgctg agctttgggc cattgacacg
     4981 gctaataaaa tttaaatgaa caatgatggt attagccaac tgggtcgatt ttgaggagaa
     5041 aacaggagtc ctgagagcaa tacggtgagg tctgctgttg atggtgttga tgcttaagca
     5101 ggctcacagt cgcagcaacc tgcgtgtaag gaccttggtc gcaatggtca aaacccaacc
     5161 atcacgtcca aggccgctta cactccggtt gctaaccgct cctgctcgcg ctcttatttt
     5221 ttatttctga aatctcaacg cgtggtgtat tctataactt agttgttcaa aaaagggagt
     5281 ttactatgga taaagcaacg caagcatata atgattcatc cattcaggtg ctgcatggct
     5341 tggaagctgt gcggaagcgt ccggggatgt atattggttc caccgatggc cgcggtttgc
     5401 atcacttggt ctatgaaatc gtggacaact ctgtcgatga agcgctcgcg gggtttgggg
     5461 atgagatcaa tgtgacgatt cacgccgata actctgtgac cgtgcaggat catggtcgcg
     5521 ggatgccaac ggggatgcac ccgagtggca aaccgacgat tgaagtcatt ttaaccgtgc
     5581 tacatgccgg cggaaaattt aaccaaaata gttacaaaac ttctggtggt ttgcatgggg
     5641 ttggctcaag cgtcgtcaat gccttatcgg aatcattaac cgtgcgagtt gtgcgggata
     5701 agcgcgcatt tgaagaacat ttcatcaatg gcggtcatcc tgatggcacg ctgcagaagt
     5761 taggaaaagt caacgaaccg aatggcacga ccatcacgtt taagccggat ccgactattt
     5821 ttcaaaccac tgttttcagt tatgatacct tggccgaacg gttacgcgaa tcagcctttc
     5881 tactgaaaaa tatcacgatt aatctgacgg atgaacgcac cggtaagcac gacagttatc
     5941 actatcctga tggtttggtc agctttgtta aatacctcaa cgaaggcaaa gatgcattgt
     6001 cgcaggtgat taattttgaa ggcaaaaagg acggtatcgt ggttgatttt gccggccaat
     6061 ataacgatgg ctattctgaa aacctgattt cgtttgttaa taacgttcgc actggtgatg
     6121 gcgggacgca tgaaattggc ttgcgcagcg gcatgacgcg agcattcaat gaatttgccc
     6181 gaaaagtcgg cttgctgaag gaacgcgaca agaaccttga aggcagtgat gtgcgtgaag
     6241 gttttgcagg tattttaagt gtccgcattc cagaagaaat tttgcaattt gagggccaga
     6301 caaagggtaa gcttggtacg ccgcaagccc gcactgtggt cgatggaatt gtctatgaca
     6361 agctgtcaac ttttttgatg gaaaacggtg aagagtcgca agagctggtt cgtaaagccg
     6421 tcaaagcccg tgatgcgcgg gaagcggctc gaaaagcacg cgatgatagc cggacgggac
     6481 gcaagcgcaa gaaggatcaa ggtttgcttt ccggtaaatt gaccccggcg caaaccaaga
     6541 accctaagcg taacgaattg tatctcgtcg aaggggattc tgccggtggt tcagctaaac
     6601 agggccgaga ccgaaagttt caggcgatct tgccattgcg aggaaaagta ctgaataccc
     6661 agaaggccaa gttacaggac atcgttaaaa acgaagaaat caatacgatg atttacacca
     6721 tcggcgctgg tgtcggtgcg gattttgatc tgcagcaggc caactacgac aaaatcatta
     6781 ttatgactga tgcggatact gatggcgcgc atattcagat tttgctacta accttctttt
     6841 atcgctacat gcggccgctg attgacgcag gccgaattta cattgctttg ccaccattgt
     6901 atcggttgca aaaaggcgct ggtgctaaaa ccaagatcag ttatgcctgg accgatgaag
     6961 agttggccaa agagaccaag gccatgggca agggttacac attgacccga tttaaaggac
     7021 ttggggaaat gaatgccgac cagctttggg aaacgactat gaatcctgag acgcggactt
     7081 tgatccgggt tcggattgac gatgctcagc tggcggaacg acgcgtgacc actttgatgg
     7141 gtgatcgcgt tgagccgcgt cgtgaatgga ttgagcataa cgtcaagttt gatatggatg
     7201 acgacggcag tattttggaa accccgactg ctaatcacga aaaattacag tttggtgcca
     7261 agcaaatcgt caaacaactg gacaagaaag gaaagtaaaa gccattggcc aatcagattc
     7321 aagaactgac cttagaagag gtcatgggcg accggtttgg caggtactcg aaatacatta
     7381 ttcaagaacg ggcgctgcct gatgtgcgtg acggcctcaa accggttcag cgtcgcattt
     7441 tatttgcgat gaaccaagat ggcaatacgt atgataaggg cttccgcaag tcggctaaaa
     7501 gtgtcgggaa tgtcatgggt aattatcatc cccacggcga cagctccatt tatgaagcga
     7561 tggttcggct aagccaggat tggaagttac gggccccact gattcagatg cacgggaata
     7621 acggttccat ggatggtgat ccgccagctg caatgcgata tacggaagcg cgtttaagca
     7681 aaatcagcaa ggaaatgctg gccgatatcg ataaggaaac cgtcgatatg gtgttgaact
     7741 ttgatgacac ggcacaggag ccaactgtgt tgcccgcagg atttccgaat ttgctggtga
     7801 atggtgcaac gggcatctct gcaggttacg cgaccgaaat tccgccgcat aacttgcgcg
     7861 aagtgatcaa tgcggtctta tacttgctga agcatcccac tgctgattta gatactttaa
     7921 tgcaatacgt caagggtccc gattttccaa caggtgggat tattcaaggg cttgatggta
     7981 tcaagcaagc ttacgaaacc ggccgcggta aaatcgtggt tcgttctcgg acacacatcg
     8041 aaaccattcg tggcggtcgt gagaagatcg tggtcactga gatcccgtat gatgtcaata
     8101 aagcgcagat gattaaaaaa atcgatgaat tacgcatcaa caaaaaagtg gacggtatcg
     8161 ccgaagtccg tgacgaaagc gaccgttttg ggcttagcgt tgtcatcgaa ttaaaaaaag
     8221 aagccgatgc acatggcatc ttaaactatt tatttaaaaa taccgatcta caaattgcat
     8281 acaactttaa catggtcgct attgccgaca tgcagccgaa gttgctaggt ctcaaggcca
     8341 tgttggaagc atacgtcgaa catcgacgcg atgtggtcac tcggcgaacg cgttttgacc
     8401 tcaacaaggc cgctgctcga cagcacattg tcgaaggctt gatcaaaatg ctatcgattt
     8461 tggatcaggt catcgccgcg attcgtgctt ccaaggataa aggtgatgct aagcgtaact
     8521 tagtcaagaa gtttgatttt tcggaagctc aggcggaagc gattgtttcc ttgcagctgt
     8581 atcgattgac caataccgat atcacggctt tacagaaaga agcagcacaa ttggcgaaag
     8641 caatcgccga gtatcaagat attttggccc gccccgctgc ccgcgatcgg gtgattgaag
     8701 gcgagttgaa gcggattgcc gaggagtacg gggatgatcg tcgcagcagc attcaagcca
     8761 aaattgaaac gcttgaagtg gcgacaacgg tgacggtggc tgatgaaacc gtcatggtgc
     8821 aggtttctcg tgatggctac gttaaacgca gttcactgcg cagttatcag gcggttgatc
     8881 cggccgacaa tggtttgaag gccaatgatc ttgccatttt cactggcgaa ctgagtacgt
     8941 tgcagcatct ttacatcgtg acaaatgccg gaaatgtcat ttatcgacca gtgcatgaaa
     9001 ttagtgatgc gcgttggaaa gacaccggcg aacacttaag ccaaacagtt ggccttggca
     9061 ctgacgaaaa agtcttggca gtgtttgctt ttgatcaact cgatggcgct ggcagttttg
     9121 tgttagggtc aagtgacggg tacatcaaac aaactgcctt aagtgatttg cagccacaac
     9181 ggacgtacaa gagtaagccg atgatggcga tgaagctgaa agacccagcc gcgattgtca
     9241 ccaatgcata cttcacgact gatcagcaac aggatgtctt tgtggtcagc cgccacgctt
     9301 atggactgac attcccgtta agcgatgtgt caactgtcgg tgcccgggca accggcgtta
     9361 aaagtatgga tctaaagcca gacgatgagg ttgtcaattt cattctagtg aaggatccaa
     9421 ctacggctaa ggtcggtatt ttgacccaac gtggcgcctt caaaaagatg gccttaagcg
     9481 aggtcgggga aatgagtcgt gcccgtcgtg gtttactggt cttgcgtgag cttaagcgtg
     9541 atccgcatcg gattgtcgcg atgatgtcag tcgatgacgc tacccgcctg aatgttttga
     9601 ccgatacggg taaggtaacg acccttaatc cggcacaaca tccagcgggt gaccgctatt
     9661 cgaatggttc gtttgtcatt gacactgatg tccttggcaa gccagttttt gttcaaacca
     9721 aagaagaacc agcagatcaa gtcgaataaa tggtgatcat tgacgccgcc gtctgtacta
     9781 atacagatgg cggcgctttt gattattata ggacagacca gttgtgtaca atttaacaaa
     9841 atgccgaaat catgggcgaa aagaagcgac taagcacact taaaaaacaa tataacgcct
     9901 attatatggg caataaaacg cttgcataga tttggcggcg tgttatactg tgtttgtaag
     9961 aactgtcaca tctgtaatcc actttaggag gcaaacaact atgaaacagc ttgacgaaat
    10021 caaagttcct aattattggg aaggctttaa cggcggcgac tggcaagaag aaattaatgt
    10081 gcgcgatttt atcgagcata acctgaacca atatgacggg gacgaaagtt tccttgctgg
    10141 ccccactgaa gcgacaacag tcctgaacaa tcaggttcta aatttaaaga aacaagaacg
    10201 tgcaaatggc ggtgttttgg atgctgacaa caatattcca tctacgatca cctcacacgg
    10261 ccctggttat ttgaacaaag atcttgaaaa gattgttggt gttcagaccg acaagccatt
    10321 caaacgagca ttcatgccat ttggcggtat tcgaatggct gaagatgcat tggaatctta
    10381 tggcttcaag acagatcctc aagaacacaa gattttcaat gaatatcgta agacccataa
    10441 ccaaggtgtc tttgatgctt atacccctga tatgcgaaag gctcgccatt acaagatcgt
    10501 gactggcttg ccagacgcat acggccgtgg ccggattgtt tctgatttcc cacggatcgc
    10561 tgtttacggg atcgatcgtt tgatggccga gaagttcaag gattataact tgaccggcga
    10621 cggcgaaatg actgacgacg tgatcaaact gcgtgaagaa atcaatgaac aatatcgtgc
    10681 cttaaacgac atgaagaaga tggccaagga atatggctat gacatctcgc gtccggcagc
    10741 taatgcgcaa gaagctgttc agtggatcta ctttggctat ctggctgctg ttaagactca
    10801 aaacggtgcc gcaatgtccg ttggccggat cgatacggtt attgatgctt atatccaacg
    10861 cgatatgcgc ttaggcaaat tgaacgaaga acaggcacag gaactgattg atcatttggt
    10921 tatgaaattg cggatggttc gtttcatccg gactgaagaa tataactcac tgttctcagg
    10981 cgatccaatc tgggcaacct tgtcattggc aggaatgggc aatgatggcc gtcaccacgt
    11041 taccaagacg gctttccgtt tcctgaagac tttggacaac atgggcgcag caccagaacc
    11101 aaacatcacc ttgctttgga gcgaacgctt gccagaaggc ttcaaacgct atgcaaccga
    11161 agtatccatt caaagttcaa ccattcaata tgaaaatgat gacctgatgc gcaacgaatg
    11221 gggtaccgat tactacggta ttgcttgctg tgtctcggcg caaccaattg ctgatggcgt
    11281 tcaatacttt ggtgcccgtg ctaacttagc taagacagtt ctgtatgcga tcaacggtgg
    11341 gaaagatgaa attcaggaag cgcaagtagg gcctgaatat gcaccgatca ccagcgatta
    11401 cattgattac aaagaattca tgaataagtt cgacaagatg atggactggc tggccgacac
    11461 gtatgtcaat gctttgaatg tgattcacta tatgcatgac aagtattatt atgaagctgc
    11521 acagctggca ttgaaggata cccaactgaa ccggaccttc gcaaccggga tttccggcct
    11581 atcacacgca gttgattcca tcagtgcaat caagtatggt catgtcaagg caattcgcga
    11641 tgaaaacggt gttgcagttg acttcgttgc tgacaatgat gactatccac gctatggtaa
    11701 caacgatgat cgcgctgatg acatcgctaa gtggttggtt aagaccttct ataacaagat
    11761 gaacacgcat catctgtatc gcggcgcgaa gttgagcacc agtgtcctga ccattacctc
    11821 caacgtggtt tatggtaaga atacagggac aacaccaaac ggtcgtcaaa aaggcgaacc
    11881 attctcacca ggtgccaacc cggcatacgg cgcagaaaag aacggcgcgc tggcatccct
    11941 gatgtccacc gccaagattc cgtatcatta cgcaactgac ggcattagta atacgtttgg
    12001 ggttactccg aacacactgg gccacgatga tgaaactcgt aaggatacct tggttcacat
    12061 ggttgacggc tatatggaaa acagcggcat gcatttgaac atcaacgtct tcaacaagga
    12121 gaccctgatt gatgctcaga agcacccaga agaataccca acattgactg ttcgggtttc
    12181 tggctactgc gtctacttcg cagatttgac caaggaacaa caagacgatg tcattgctcg
    12241 gaccttcttc gaagaaatgt aagcagctta actcaagaca ggaagccatt cctgttttgc
    12301 caaaagacgg caacgatgct gttgccgttt tttggcagaa tgaaatgaaa atcaattgaa
    12361 aacgacacat gatgttgtag tggaggcaat aagatgaaac tcatcgatca gtcacaaagc
    12421 ccattaaata tcttagaaca agttggtcag gatcatgatg gcccgatcaa agggtatgtt
    12481 cactcggtcg aaagttttgg ttcggtcgat ggccctggta ttcgcttcgt tgtctttatg
    12541 caagggtgtc gcatgcgttg ccagtattgt cacaaccctg acacctggaa cattggggtt
    12601 ggtgaagaaa tgacggccga tcaaattttg gcggatgccc agcgctataa agcattctgg
    12661 ggtgaccaag ggggtattac ctgcagtggc ggtgagagtt tggtacaaat cgatttcatt
    12721 ctcgaactct tcaccaaggc taaggcactg ggaatttcga cttgcctcga tacgtcaggc
    12781 ggccccttca cgcgtgacca accgtggttt ggccagtttg aaaagctgat ggctgttact
    12841 gacatctcat tagttgatat taaacacatt gattcggccg agcataaaaa gctcaccggt
    12901 tttcctaatg aaaatatttt ggatatggtg cagtatatgt cggcgcatgc tgatgacatg
    12961 tggattcgcc acgttctggt cccggaacgc actgactttg acccttatct caaacggtta
    13021 ggggactata ttgcgacatt ggacaaaaat gtggtccaaa aagttgagat tctgccgtat
    13081 cacacattag gcgttaaaaa gtatcacgag cttggcatta cgtacccgct tgaaggcatc
    13141 gaaccgccgt ctgccgatcg cgttaagaat gcagagaatc tgctgcacgt taaggattat
    13201 accggatggc aaagctggcg tccgaaacca gttgcgagca actgaatttt tagctagaac
    13261 ttaacgtaac gattaaaaac gcggcaaatt cgttgcgttt tttttcattg ccacttatga
    13321 tgatggttga acgatattat taaattataa acgaaaggga agccgcccta tgaaaacgaa
    13381 acaagagcgc attttttcct caaagacact aacttatttt ctgcaattgg cagaaaccat
    13441 gaactacacc caagccgccc aattgcttgg cattacccag ccagccttaa cacagcagat
    13501 caagaaattg gaacggacgg tgggggcacc gctgttttat tctgtcggga agaaactgca
    13561 tttatctgac gctggtcaga ccatgttaaa gtcaacccat gagatctacg agatcttgaa
    13621 ccagacaacc gacgaaattc aacaaacaac cagtgcaacc gtcggaaaaa tcaatattgg
    13681 gttattaagc tcaatcgagg atagcgcctt tattgcgttc attgctcatt actatcaact
    13741 gaatcctgaa gttgaagtga cgctacggat gatgacccgt cacgaaattt gggaatcctt
    13801 ggaaaacaac cagattgatt tggctatcat gaatctgcca gatgagacca ttaagaactg
    13861 gaaaccatac gccagcaaga aaattattga tgaacaattg ctgttcttgc accacgatga
    13921 cgcattggct aaccgtaagc gaatccattt caaagatact ttagctgaac cttgggcaac
    13981 ttatcctgac gactatttcc ttggacagct tctgcgtgag gcgtacaaga atcaaatggt
    14041 tgatttcccg cacgtggtcg cacatttcac cacgccatat cagttaaccc aattcgttaa
    14101 cttgtcaggg gtcaacacgg ccttgccaac cagttttgtt cgggcacgcg ctgatcaaat
    14161 caaggcctat gctattgcgt ttgatccggc cattcgtttt gagatttctt ttgtttatcg
    14221 caaagagaaa gctgacattc cgcggatctc gaacttcttc cagacctttg acgattatct
    14281 gaaggaaaaa gattacttgt cgcgggtcag tgaaaaccgt gttaaacttg ataagtaaac
    14341 tattcagttg aggagcgatc agataagatg acgactttga tttttgggca tcagaacccg
    14401 gacaccgacg cgattacgag tgccatgagc tgggcagaat ttcagaaaca ggcaggcaac
    14461 acggatgttg aagcggtagc attaggcgaa ccgaacgatg agactaagtt cgtctttgat
    14521 cacttcaagg ttcaggcacc gcgggttatc aagacggcag ccaacgagac ggatcatgtc
    14581 atgttggttg atcacaacga atttcaacaa agtgtcagtg atatcgaaga cgtgacgatt
    14641 gattctgttg tcgaccatca tcgcatcgct aacttccaca cggcagcgcc gctgttttac
    14701 cgagcagaac cggttggcag caccaatact gtcatttttg agatgttcca ggaatatggc
    14761 ttcaagattt cgccaacatt ggctggtttg atggcttctg gtttgatttc agacacgctg
    14821 ttgttgaagt cgccgaccgc aaccgataag gataagaaga ttttgccaga aatggcgaag
    14881 attgccggaa ttgatttgca gtcatatggt cttgccatgc tgaaggcagg tactaatttg
    14941 gccgccaagt cagatatgga cattatcgaa ggcgatgcta agagtttcac catgggcggc
    15001 aagtctattc gcatcggaca ggtcaatacc gtcgatctga atgacattta cgcacgtcag
    15061 gacgaattgg tcagtgccat gaccaaagag gcgcaggcga aaggctacga cgatttcctg
    15121 ctgattgcca ctgacatctt ggacagcaat tcaactggtt tcgcagtcgg tgctgaccgc
    15181 gataaaatcg ccagtgcttt taacgaacag ttcgacaagg acgcgcgttt ggcattgcct
    15241 ggggttgttt cccgcaaaaa gcaggtcgtt ccgccaatgc agagcacgtt tgaaggttaa
    15301 ctttcatctt taattgcaca caattgttct aaggaaagtc gcagctagcc agttgcggct
    15361 tttttgtttg caaaaagtct ctagccatct ttttgcgaaa tctgttaaat ataaagctgg
    15421 ctcgcagctc gtgatgcgtg aatttgaaat ttgtgtagca attcgcgggt cgaatcaacg
    15481 taagcgcacg attgtgaggt acatttaaaa cggcttcgga ttcccttatg attgaggaaa
    15541 tgccgaagcc gttgtctttt attgaggttt atcttgca
//
