LOCUS       c00145_gnlPro..        12202 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JKGLLCEP_145.
ACCESSION   c00145_gnlPro..
VERSION     c00145_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 20:58:47
            Original ID  :: gnl|Prokka|JKGLLCEP_145
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12202
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12202
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2514:5439]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2515..5439
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
     cand_cluster    1..12202
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="single"
                     /product="porA"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12202
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="porA"
                     /region_number="1"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     CDS             185..619
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transketolase_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg145_1"
                     /sec_met_domain="Transketolase_N (E-value: 7.3e-08,
                     bitscore: 21.7, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LGGDAYVNTIKNLGGNPENPFTIFPEVAELYAKRAEELKKIVADK
                     YAAKAEWAKANPEKAAKLAEFFSGKAPKVNWDAIEQKAGGATRAGSATVLGALATQVEN
                     MIVSSADLSNSDKTDGFLKKTHAFKKEISAALSFKQEFQS"
     CDS             643..1395
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transketolase_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transket_pyr"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg145_2"
                     /sec_met_domain="Transketolase_C (E-value: 5.1e-10,
                     bitscore: 29.4, seeds: 80, tool: rule-based-clusters)"
                     /sec_met_domain="Transket_pyr (E-value: 2.5e-22, bitscore:
                     69.5, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLHGGIIAACGTFFVFSDYMKPALRMAALMEQPVKFIWTHDAFR
                     VGEDGPTHEPVEQEAQVRLLEKLKNHKGHNSMLVLRPADVEETTIAWKLAMENMSTPTA
                     LILSRQNIVNLPAGTDYSQAAKGAYIIADADENPDVILVASGSEVSTLVAGAELLRKEG
                     VKVRIVSAPSEGLFRNQSKEYQESILPAGAKIFGLTAGLPVNLEGLVGSNGKVFGLESF
                     GFSAPYKVLDEKLGFTAENVYNQVKAML"
     CDS             1478..1912
                     /locus_tag="ctg145_3"
                     /transl_table=11
                     /translation="MKKIGICCDHAGFELKEYVRGWLEAKGWEYKDFGTYSTDSCDYPD
                     FAHPLALAVEAGECYPGIAICGSGNGISMTLNKHQGIRAALCWTAEIAHMARLHNDANV
                     LVMPGRYISTEEADMIMTEFFSTEFEGGRHQKRIDKIPVK"
     CDS             1970..2194
                     /locus_tag="ctg145_4"
                     /transl_table=11
                     /translation="MGVYQGSLQISELLIHSPFYSPLANAREGYNSLYSSSEQYQIDKY
                     LFYFHPLFFSVFLFFTVEMNRLKDKKLSL"
     CDS             2221..2496
                     /locus_tag="ctg145_5"
                     /transl_table=11
                     /translation="MDQLKTIKELINQGDIENALQALEEFLQTEPVGKDEAYYLMGNAY
                     RKLGDWQKALNNYQSAIELNPDSPALQARKMVMDILNFYNKDMYNQ"
     CDS             2515..2742
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_6"
                     /sec_met_domain="Fer4_7 (E-value: 1.4e-13, bitscore: 41.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 3.7e-09, bitscore: 26.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 5e-09, bitscore: 26.2,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.1e-06, bitscore: 19.1,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKIKGAIVVDTERCKGCNLCVVACPLNVISLAKEVNVKGYNYAQ
                     QILEDTCNGCSSCATVCPDGCISVYKVKVE"
     CDS             2754..3836
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_7"
                     /sec_met_domain="PFOR_II (E-value: 4e-29, bitscore: 91.1,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1.2e-49, bitscore: 159.2,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEEVVLMKGNEAIAHAAIRCGADGYFGYPITPQSEVLETLAELR
                     PWETTGMVVLQAESEVAAINMVYGGAGSGKMVMTSSSSPGVSLKQEGISYLAGAELPCL
                     IVNVMRGGPGLGTIQPSQADYFQTVKGGGHGDYKLIALAPASVQEMADFVGLAFELAFK
                     YRNPAIILADGVIGQMMEKVVLPPAKARRTDAEVIAQCPWASTGKTKDRKPNIITSLEL
                     RPEEMEKNNLRFQAKYRVIEENEVRFEEIDCEDAEYLIVAFGSMARIGQKAMELAREEG
                     IKVGMLRPITLWPFPTKAIAEYANKVKGMLVTELNAGQMVEDVRLAVNGRVKVEHFGRL
                     GGIVPDPDEIVTALKEQLIK"
     CDS             3847..4020
                     /locus_tag="ctg145_8"
                     /transl_table=11
                     /translation="MNPDKIRNVLNILFMILALAAIITYFVAKDDFKVFIYVCGAAIFV
                     KLMEFFIRFTNR"
     CDS             4117..4878
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_9"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.5e-26, bitscore:
                     82.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKEEIIKPENLVYKKPTLMNDNGMHYCPGCSHGVVHKLIAEVIE
                     EMGLEDKAVGISPVGCAVFIYNYLDIDWQEAAHGRAPALATAIKRLWPDRLVFTYQGDG
                     DLACIGTAETIHALNRGENITIIFINNAIYGMTGGQMAPTTLMGMKTATCPYGRDPELH
                     GYPLKITEIAAQLEGTAYVTRQSVQSVPAIRKAKKAIRKAFENSMNGKGSNLVEIVSTC
                     SSGWKMTPEKANKWMEEHMFPFYPLGDLKDK"
     CDS             4897..5439
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_10"
                     /sec_met_domain="POR (E-value: 2.4e-36, bitscore: 115.5,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEEIIIAGFGGQGVLSMGKILAYSGLMEGKEVTWMPAYGPEQRG
                     GTANVTVIVSDDKISSPILSKYDTAIILNQPSLEKFESRVKPGGILIYDGYGIINPPTR
                     KDIKVYRIDAMDAANEMNNAKAFNMIVLGGLLKLRPIVTLENVVKGLKKTLPERHHHLI
                     PMNEEAIKKGMELIREA"
     CDS             5562..7604
                     /locus_tag="ctg145_11"
                     /transl_table=11
                     /translation="MRRILLTYILLVVGLLTAQAQFNPTQQVDPRTGRDANGNQIDPAM
                     RVQEDSTDVEIQGLPPTLYMWHVSENLGTIQRIPADTATHMFQNTNLVEGLTGHYNYLG
                     NLGSPRLSRLFFERRDAEPTIFMEPFSSFFIRPDEFNFTNSNVPFTNLTYYKAGNKING
                     EERFKSYFSVNVNKRLAFGFNFDYLYGRGYYNNQNTSYFNAALFGSYIGDRYEATLLYS
                     NNYLKMNENGGITDDRYITRPEEMAEGKKEYESQNIPTLLSKSANRNKDFYIFLTQRYK
                     LGFTREVEKAKDDTTNTQKIEFVPVTSFIHTMKVERSRHQFTSEDELYKIYPEAYIQPG
                     NKLVNDSTSYIGVKNTLGIALLEGFNKYAKAGLTAFISHKLSNYRLMDRDSVSVDKYSE
                     HEVFVGGELAKRQGKTLHYRAMGEVGILDKAIGQFRVNADLDLNFRLWKDTVSFIARGS
                     ISNTLPAFYMRHYHSKYFYWDNDNMEKEFRTRLEGELNIEHWQTNLKAGVENIKNYTYF
                     NQKALPQQNGGNIQVLSATLSQNFRLGILHLDNEVTWQKSSNNTVLPLPELSLYHNLYI
                     QTTLAKKVLHVQLGADVRYFTKYYAPAYTPAIQQFHLQPEDDQVKIGGYPIINVYANLQ
                     LKRTRLFAMMYHVNQGMGNSNYFLSPHYPINPRLFKIGVSWNFYD"
     CDS             7613..8437
                     /locus_tag="ctg145_12"
                     /transl_table=11
                     /translation="MNLLRPKYLKYVVLGLISALVVTCWPRKEKPKGHPRDYAEIKESG
                     ILHAATEYNSISFYVDGDTVSGFHYELIEAFARDKGLQVQVSPVMSFNQRLEGLANGTY
                     DVVAYGIPATSELKDSLLLTSPIILSKQVLVQRKVGENDSLAIRSQLDLAGKTLNVVKG
                     SPSILRIRNLSNEIGDTIYVNEIEKYGSEQLIAMVAHGDIDYAVCDEGIARMAVDSLPQ
                     LDINTAISFTQFYSWGVSKQSPALLDSLNTWLSDFRKKGEYQSVYRKYYGKQ"
     CDS             8673..9638
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg145_13"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 3e-21, bitscore:
                     66.6, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGIHWLRRGDQIQKRTCFSESRRLQSSGSHEPCGKKAKAYAKERN
                     IPKWYDDAQELIDDPEVNAVYIATPPSSHATYAIMSMKAGKPVYIEKPMAQTYEECARI
                     NRISQETGVPCFVAYYRRYLPYFMKVKELVDKGTIGNVINVQIRFAQPPRDLDYNRENL
                     PWRVQADIAGGGYFYDLAPHQIDLLQEMFGCILEASGYKSNRGGLYPAEDTLSACFQFD
                     NGLVGSGSWCFVAHDSAREDRIEIIGDKGMICFSVFTYDPIALHTERGREEIMVENPEH
                     VQQPLIQAVVDHLLGKSTCSCDGESATTTNWVMDKILGKI"
     CDS             9792..10736
                     /locus_tag="ctg145_14"
                     /transl_table=11
                     /translation="MELKQFKIAVLPLRDKLLSYARKLTDDHSDAEDAVQEVMLKLWNL
                     RPKLDEYHSIEALAMTMTHHTCMDILRGKHPDNLSLDSVQAASPVATPERLLEEKDEFS
                     LMRHIISTLPPLQQTILRMKDVEEYETEEIAEITGCSSEAIRSNLSKGTEKSKRHLPAN
                     HTTKKKEKRSMNIEELLNKYFEGETTCEEERELRRFFTRGIVPEHLQMYRPMFAFLNEE
                     NRQSKTAVPEVPKTSVPLRRRLLYIFSGMAAGILLILGIAGLNRHFNTPTANYVIIDGK
                     CYTDAKLVREQAMIAFRDVSISEEEVFATLFSE"
     CDS             10764..11213
                     /locus_tag="ctg145_15"
                     /transl_table=11
                     /translation="MNKVIRTTWIILLLTVASGMARAQQGLQIASVFQKYGKQKGVTMV
                     ELSNEMLETYQMTLYKSLVFKDVEEALPTILNCLDADKKKAKKVKEVVAGGQIQSGYYQ
                     LPQLKEDVNRFILFKTGKKGSATLIYIEGELDADDLVTMLFMKKN"
     CDS             11227..12198
                     /locus_tag="ctg145_16"
                     /transl_table=11
                     /translation="MKHIYLLLFMLIPMAGMAQEGISQDTTLYVNGRKILIKENEGKIK
                     VKLYEQSSHGDTIENDQIFEGIYTDGQTTERRTAFTVPFVKRKNHYRFDPHIAGFYMGY
                     TRLSDGINFNTPDGLNINANKSWEIGFNLFQGSLTLSRDRQWGITTGLGWGYRSFRLGN
                     NYAFRQIDGVTGIVPGVPDEEVYTKSRLRYFYFRIPVALEWQKRFSHSNAHGPLFFSAG
                     LEAEIRHGAKSKAKVNGHKKNLDSDLNVHPVGINLLAQAGYGDIGVYLRYSTYSLFEHK
                     KRSRTLSLLFRSVLVLVTGSPTDGNHTPGRRHQQSDYSKTIS"
ORIGIN
        1 tgggactgga agtaatcaca atcaacggta acgatacctg acgagatacg caaagcactg
       61 actgaagcca aagctgaaaa gaaccgtacg aaccctgatc atcggtaaaa cgaccatcgg
      121 gtaaaggagc acgccgggcc gatggaagca gcatgaagcc gactgcgcga cacacggcgc
      181 accattgggc ggagacgcat atgtgaatac aatcaagaac ctgggtggaa atccggagaa
      241 tccattcacc attttccccg aagtagccga actgtatgcc aaacgcgcgg aagaactgaa
      301 gaagattgtt gctgacaaat atgcagcaaa agcagaatgg gcaaaagcaa accctgaaaa
      361 ggcagctaaa ctggccgaat tcttctctgg aaaagccccg aaagtaaact gggatgccat
      421 tgaacagaaa gccggcggcg caacccgtgc cggatctgca accgtattag gagcattggc
      481 cactcaggta gaaaatatga tcgtttcatc agccgacctg tctaactcag acaagacaga
      541 cggattcctg aaaaagacgc acgcattcaa aaaggagatt tcagcggcgc tttccttcaa
      601 gcaggagttt cagagttaag tatggcttgt atttgtatcg gtatgtctct gcacggaggt
      661 atcattgctg catgcggcac attctttgtg ttctcagact acatgaaacc ggccctgcgt
      721 atggctgccc tgatggagca accggtaaaa ttcatctgga ctcatgatgc gttccgtgta
      781 ggagaagacg gacctactca cgaaccggta gaacaagaag cacaagtacg cctgcttgaa
      841 aaactgaaga accacaaagg acacaactct atgttggtac ttcgcccggc ggatgtggaa
      901 gagacaacca ttgcgtggaa acttgcaatg gaaaacatgt cgactcctac agcactgatc
      961 ctttcacgtc agaatatcgt taacctgccc gcaggaaccg attattcaca agctgcaaaa
     1021 ggtgcttata tcattgccga cgccgatgaa aacccggatg tgatcctagt agcttcgggt
     1081 tcggaagttt caacgctggt ggccggtgcc gaacttctgc gcaaagaagg tgtgaaagta
     1141 cgtattgttt ccgctccgtc cgaagggtta ttccgtaatc aaagcaaaga gtatcaagaa
     1201 tccatacttc ctgcaggagc caaaatcttt ggtctgacag ccggacttcc ggtgaatctt
     1261 gaaggtttgg taggttccaa cggtaaagtg ttcggtcttg aatcatttgg tttctcggca
     1321 ccctacaaag tgctggatga gaaactggga ttcaccgcag aaaacgtata caatcaggta
     1381 aaagcaatgc tctgatcaat cattaaatgt gctaatgcgc taatccggca ggatcagtgc
     1441 attagcacat tcattatatt agcacattaa aaaggacatg aagaaaattg gaatttgttg
     1501 cgaccacgcc ggtttcgaat tgaaagaata cgtaaggggc tggctggaag caaaaggttg
     1561 ggaatacaaa gacttcggaa cttactcgac agacagctgt gactatcccg attttgccca
     1621 tccattggca ctggctgttg aagccggcga atgctatccg ggaattgcca tctgtggtag
     1681 cggtaatggt atcagcatga cattaaacaa acatcagggt attcgtgccg cactctgttg
     1741 gacagcagaa atcgcacaca tggcacgcct gcacaacgat gccaacgtat tggttatgcc
     1801 cggccgttat atcagcacgg aagaggcgga tatgattatg acggaatttt tctcgacaga
     1861 gtttgaaggc ggacgccacc agaaacgcat tgataaaatt cctgtaaagt gagagtctcc
     1921 cctatcgacc tccatatcaa atcgatagaa gactgacttt aataacaaca tgggagtgta
     1981 tcaaggttca ctgcagatta gcgaactttt gatacactcc cctttttata gccccctcgc
     2041 aaatgcccgg gaaggataca atagcctcta ttcatcctca gaacagtacc agattgacaa
     2101 atacctattt tatttccacc ctctattttt ttctgttttc ctatttttca cagtagagat
     2161 gaacaggtta aaagataaaa agctatcttt gtgactcaat aatccggaaa atcaaaagat
     2221 atggatcaac tgaaaaccat caaagagctt atcaatcaag gagatataga aaatgcgctt
     2281 caagcacttg aagaatttct ccagactgaa cccgtcggta aagacgaagc ttactatctg
     2341 atgggaaatg cttaccgcaa gttaggagac tggcaaaaag ccctcaataa ttatcaatcc
     2401 gccattgaac tcaatcccga cagcccggct ctccaggcac gcaaaatggt gatggatata
     2461 ttgaacttct acaataaaga tatgtataat caataaacgt aataaaaata gattatggca
     2521 aaaatcaaag gagcaatcgt agtcgacaca gagcgttgca aagggtgcaa cctgtgtgtg
     2581 gtagcttgtc cgctcaacgt aatatccctc gccaaagagg tgaatgtgaa agggtataat
     2641 tatgcccagc agattcttga agatacctgt aacggatgca gttcatgcgc aaccgtatgt
     2701 ccggacggat gtatctctgt ttataaagta aaagtagaat aaaagaaaag aatatggcag
     2761 aagaagttgt attaatgaaa ggaaacgaag ccatcgccca tgcggccatc cgctgtggtg
     2821 ccgacggata cttcggatat cctattactc cgcaatcgga ggtgttggaa actcttgccg
     2881 aactgagacc ttgggaaact accggcatgg tagtcctcca ggcggaaagt gaagtggcag
     2941 ctatcaatat ggtttatggt ggtgccggaa gcggcaaaat ggtgatgacc tcatcatcaa
     3001 gtcccggtgt cagcctgaaa caggaaggta tttcttatct ggcaggtgcc gagcttccat
     3061 gtctgatcgt aaacgtgatg cgcggcggcc ccggtttggg tactatccaa ccaagccagg
     3121 ccgactattt ccagactgta aaaggtggag gacacggtga ctataaactc atcgcattgg
     3181 ctccggcttc tgttcaggaa atggcagact ttgtcggact cgctttcgaa cttgcgttca
     3241 aataccgtaa tccggccatc atccttgcag acggtgttat cggacaaatg atggagaaag
     3301 tggttcttcc tcccgcaaaa gcccgccgta cggatgcgga agtcatagca caatgtccat
     3361 gggcttctac cggaaagaca aaagaccgta agcccaacat catcacttcg ttggaactgc
     3421 gtccggaaga gatggagaaa aacaacctcc gcttccaggc aaagtacaga gtaattgaag
     3481 aaaacgaagt acgttttgaa gaaattgact gcgaagatgc agaatatctg attgtagctt
     3541 tcggttcaat ggcacgtatc ggccagaaag caatggaact ggcccgtgaa gaggggatta
     3601 aagtcggtat gcttcgcccc atcactctat ggccgttccc gacgaaagcg attgccgagt
     3661 atgccaataa ggtaaaaggt atgctggtaa ccgagctgaa tgccggacag atggtagaag
     3721 acgttcgttt agcagtgaac ggaagagtga aagttgaaca tttcggccgc ctgggaggaa
     3781 ttgttcccga tccggacgaa atagtaactg cattgaaaga acaattaatc aaataactac
     3841 agtacgatga atcccgataa aataagaaac gtattgaaca tactgtttat gatattggct
     3901 ctggcagcta ttatcaccta cttcgttgcg aaggacgact ttaaggtgtt tatctacgta
     3961 tgcggcgcgg caatttttgt caagctgatg gagtttttta tacggttcac caacagataa
     4021 gtatccgggc cttgaagcat tttaagtctg cgtagtttaa gacacccgaa cttagaacaa
     4081 gcaagcccgg tcacttaaag ataaaaaaaa gaagttatga cgaaagaaga aataatcaag
     4141 cccgagaatc tggtttataa gaaaccgact ctgatgaacg acaatggcat gcactattgt
     4201 ccgggttgca gccacggcgt tgtacataaa ctgattgccg aagtaatcga ggagatggga
     4261 ctggaagaca aagcagtcgg tatctcaccc gtaggttgcg ctgtatttat ctacaattac
     4321 cttgacattg actggcagga agctgcacac ggacgtgcgc cggcacttgc cactgccatc
     4381 aaacgtcttt ggccggatcg cctggtgttc acctatcagg gagatggcga ccttgcctgc
     4441 atcggtacgg cagagactat ccacgcattg aatcgtggtg aaaatattac gattatcttt
     4501 atcaacaatg ccatttacgg tatgaccgga ggccagatgg ctcctactac cctgatggga
     4561 atgaaaaccg ccacttgtcc ttatggacgt gatccggaac tccacggata tccgttgaag
     4621 ataactgaga ttgctgccca actggaaggt acagcttacg taactcgtca gtcggtacaa
     4681 tccgttccgg ctatccggaa agctaaaaaa gcaatccgta aagcttttga aaattcaatg
     4741 aacggaaaag gctccaacct ggtagaaatc gtttcgacct gtagttccgg ctggaaaatg
     4801 actccggaga aagccaacaa atggatggaa gaacacatgt tccccttcta tcctcttggc
     4861 gacttgaaag ataaataata agttaatatc attaagatga aagaagaaat aattatagca
     4921 ggattcggtg gacagggtgt actgtctatg ggaaagattt tagcctattc cggactgatg
     4981 gagggcaaag aagtgacctg gatgccggct tatggtcctg agcaacgtgg cggaacagcc
     5041 aacgttacag tcattgtaag tgacgacaag atctcttcac cgatcttgag caaatatgat
     5101 acagctatca ttctgaatca gccttcactg gaaaagttcg aaagccgtgt gaaacccgga
     5161 ggtatcctga tctacgacgg atacggcatt atcaacccgc ctacccgcaa ggatatcaag
     5221 gtgtaccgca tcgatgcaat ggatgcggcc aatgaaatga acaatgctaa agcattcaac
     5281 atgatcgtgc tgggaggatt gctgaaactt cgccccattg tcactttaga aaatgtagtg
     5341 aaaggtttga agaaaacttt gcccgaacgc caccatcacc tgatcccgat gaacgaagag
     5401 gccatcaaaa aagggatgga actgatcaga gaagcttaaa ctgactgaga attgagaatc
     5461 ggaatttaaa aattattagc tatgccacag gcagagatag cggataattt ttaaatttca
     5521 attctcaatt ctcattttaa taagtatctt tgcggctaat tatgagacga atcctactta
     5581 catatatact ccttgttgta ggtttgctga ccgcacaggc acagttcaac cctacacaac
     5641 aagttgatcc ccgtaccggc agagatgcca acggcaacca gatagacccg gccatgcggg
     5701 ttcaggaaga tagtacagac gttgagatac agggacttcc tccgacactt tatatgtggc
     5761 acgtcagcga aaacctgggg acgattcaaa gaatcccggc tgataccgca acccacatgt
     5821 ttcagaacac caacctggta gaaggtctga caggacatta taattatctg ggcaatttag
     5881 gttctccccg tctgtcccgc ctcttctttg aacgtcggga cgcggaaccg accatcttta
     5941 tggaaccttt ttcaagcttc ttcatacgtc ccgacgaatt caacttcacc aacagtaacg
     6001 tgcccttcac caatcttacc tactataaag ccggtaataa gatcaatgga gaagaacggt
     6061 ttaagtctta cttttctgtt aatgtgaata aacggctggc atttggtttc aacttcgatt
     6121 acctgtacgg acggggatat tataacaacc agaatacctc ttactttaat gccgcacttt
     6181 tcggaagtta cataggcgac cgctatgaag ccactttact gtacagcaac aattatctga
     6241 agatgaacga gaatggcggt atcaccgacg accgttacat cacccgtccg gaagagatgg
     6301 cggagggaaa aaaggaatac gaatcgcaga atatccctac cctgttgagc aaaagcgcca
     6361 atcgtaacaa agacttttac atattcctca cccaacgcta taaactggga ttcacgcgtg
     6421 aagtggagaa agccaaagat gacacaacca acactcaaaa gatagagttc gttccggtca
     6481 ccagtttcat ccacacgatg aaagtggaac gcagccgcca ccagtttact tcggaggacg
     6541 aactgtacaa aatttatccg gaggcttata tccaacccgg aaacaaattg gtgaatgact
     6601 ctaccagtta tatcggagtc aaaaacacat tgggaatcgc actgctcgag ggtttcaata
     6661 aatatgccaa agctgggctg acagctttca tctcgcataa gttaagcaat taccggctta
     6721 tggaccggga ctctgtaagc gtggataaat acagcgagca tgaagtcttt gtcggaggtg
     6781 aactggccaa acgccaggga aaaacgctcc actaccgcgc catgggtgaa gtgggaatcc
     6841 tggataaagc gatcgggcaa ttccgtgtca acgccgacct cgacctgaac ttccgcttat
     6901 ggaaagacac ggtcagcttt attgcccgcg gatccatcag taacactctt cccgcattct
     6961 atatgcgtca ttatcactcc aagtacttct attgggacaa tgacaatatg gaaaaggaat
     7021 tccgtacccg actggaaggt gagctgaaca tagaacattg gcaaaccaac ctgaaagccg
     7081 gagtggaaaa catcaagaac tatacgtatt tcaatcaaaa agcattgccc caacagaatg
     7141 gaggtaatat ccaagtgctt tccgccactc tgtcacaaaa cttccgcctg ggcattcttc
     7201 atctggacaa tgaagtgacc tggcaaaagt cgagcaacaa caccgtgttg cccctgcccg
     7261 aactttcact ataccataac ctctatatcc agacaacact ggctaagaaa gtgcttcacg
     7321 tacaattggg agccgatgta cgctatttca ccaaatatta tgctccggca tatactcccg
     7381 ccatccagca gttccacttg caaccggaag acgaccaggt aaagattggc ggttatccga
     7441 tcatcaatgt atatgccaac ctgcaattga aacgtacgcg ccttttcgcg atgatgtacc
     7501 acgtcaatca gggaatgggt aactcgaatt atttcttgtc accccattac cccatcaacc
     7561 cgcgcctgtt taagattggt gtttcctgga acttctatga ctaaccgccg ccatgaatct
     7621 actgagacct aagtatctga aatacgttgt attgggactg atatcagccc tcgttgtcac
     7681 ctgctggccc cgcaaagaga agcccaaagg acatccgcgg gattatgccg agatcaaaga
     7741 aagcggcatt cttcatgctg caacagaata caactccatc agcttctatg tggatggaga
     7801 tacggtttcg ggattccatt acgaactgat agaggcgttt gcgcgcgaca aaggtttaca
     7861 ggtacaggtc tctccggtga tgagcttcaa tcaacggctg gaagggctgg ccaacggaac
     7921 gtatgatgta gtggcttatg gcataccggc tacgagtgaa ctgaaagact cgctgctcct
     7981 cacctcccct atcattttaa gcaaacaagt cctggtgcaa cgcaaagtcg gagaaaacga
     8041 ttcacttgcc atcagaagcc aactcgacct ggcaggcaaa acattgaatg tcgtcaaagg
     8101 atctccctcc atcctgcgta tccgcaacct gagcaatgaa ataggcgata cgatctatgt
     8161 taacgaaata gagaaatatg gttccgagca actgatcgca atggttgctc acggagacat
     8221 cgattatgcc gtatgtgacg agggcatcgc ccggatggct gtggactcgc taccccagct
     8281 cgatatcaat accgccatca gtttcacgca attctattca tggggagtca gcaagcaatc
     8341 tcccgcccta ctcgacagcc tgaatacatg gctatccgac ttccgaaaaa aaggagaata
     8401 ccagtccgtt tatcgcaaat attacgggaa acaataaccg gctttcttcc ctcctcccct
     8461 ctcttttaaa gataacagtt accagttgta caactggtac agtacgagtt gagcaactgg
     8521 tcgtgtacga gttgtgcaac cgataccatc gtactaagga acgaacgcga acgatctcta
     8581 tcaggataac tgtaaatcat tctttgcttt cggcagaatt gagtatattt gcggaacgat
     8641 aaataaaaag atatgagcaa taagattata aaatggggat tcattggttg cggagaggtg
     8701 accaaataca aaagcggacc tgcttttcag aaagtagaag gctccaaagt agtggcagtc
     8761 atgagccgtg cggtaaaaaa gccaaagcct atgctaaaga gcggaacata ccgaagtggt
     8821 atgacgacgc acaagagtta atagacgatc cggaagtaaa tgccgtatac atagccactc
     8881 caccctcttc acacgccact tatgccatca tgtccatgaa agccggaaaa ccggtttata
     8941 tcgaaaagcc aatggcacag acttacgaag agtgtgcccg catcaaccgc atctcacaag
     9001 agacgggagt cccttgtttt gtagcctact accggcgtta cctgccttac tttatgaaag
     9061 tgaaggaact ggtggacaaa ggtacgatcg gcaatgtaat caacgtacag atccgttttg
     9121 cacagccccc tcgcgatctg gactataaca gagagaatct gccctggcgt gtacaggccg
     9181 atattgccgg aggaggatac ttctatgacc tcgcaccaca ccagatcgac cttctgcagg
     9241 agatgttcgg ctgcatactc gaagccagtg gctataaaag caaccgtggc ggactctatc
     9301 cggcagaaga tacactgagc gcatgtttcc agttcgacaa cggattggta gggagcggtt
     9361 cgtggtgctt cgtagcccat gattcggccc gcgaagaccg tatcgaaatt atcggcgata
     9421 aaggcatgat ctgcttctcc gtatttacct atgacccgat tgccctccat actgaaagag
     9481 gacgtgaaga aataatggta gaaaaccctg aacacgtaca gcagcccttg attcaggccg
     9541 tagtagacca tcttcttgga aaatccacct gttcgtgtga tggcgaaagt gccacaacga
     9601 ctaactgggt gatggataaa atattgggaa agatctgata atgaacgatg aacgatcaac
     9661 cataaacgat agagatcgtc ttacctcaca ctacattcca cctgtcagga cactacttat
     9721 tgttgatcgt tcatcatttt tttatctttt ccatgtcacg ttttccttcc ttctccgtct
     9781 tgcttatgta aatggaacta aaacaattca aaatagccgt tcttccactc cgcgacaaac
     9841 tgcttagtta tgcgcggaag ttgacagatg accactcgga tgccgaagat gccgtgcagg
     9901 aagtgatgct gaagttatgg aaccttcgtc cgaaactgga cgaataccat agcattgagg
     9961 cccttgccat gactatgacc catcatacct gcatggatat cctcagaggg aaacatcccg
    10021 acaacctatc gctcgacagc gtacaggctg ccagtccggt cgccaccccc gaacgcttgc
    10081 ttgaagagaa agacgaattc agcctgatgc gacatatcat cagtacactg ccacctctgc
    10141 aacagaccat cctccggatg aaagatgtag aagagtacga aaccgaagaa atcgccgaga
    10201 taacaggatg cagctccgaa gccatccgca gcaatttatc caagggcacg gaaaaaagta
    10261 agagacattt acctgcaaac catacaacaa agaaaaagga gaaacgaagc atgaatatag
    10321 aagaattatt gaacaagtat tttgaagggg aaaccacctg cgaagaagaa cgtgagctcc
    10381 gccgtttttt cacccggggc atcgtaccgg aacatctgca gatgtaccgc ccgatgtttg
    10441 ctttcctcaa cgaagagaac cggcagagca agactgccgt ccccgaagtt ccgaaaactt
    10501 ctgtccctct acgccgccgt ctactttaca tattcagcgg aatggctgcc ggaatattgc
    10561 ttatattggg tattgccggt ctcaaccgac atttcaacac cccaaccgct aattatgtaa
    10621 tcattgacgg gaaatgctat accgatgcca agctggtacg cgaacaagcc atgatcgcgt
    10681 ttcgtgatgt cagtatcagc gaagaggaag tattcgctac gctgttctcc gaataaaaaa
    10741 gaaaataata aaagaaacga agtatgaata aagtcattcg caccacatgg attatcctgc
    10801 tacttactgt cgcctccggc atggcaagag cacaacaggg actacaaata gcttccgtat
    10861 tccagaaata cggtaaacaa aaaggagtga ctatggtaga gctgtccaac gaaatgctgg
    10921 aaacctacca gatgactctc tataaaagcc ttgtctttaa agacgttgaa gaagcactgc
    10981 ccaccattct caactgtctg gatgctgaca aaaagaaggc aaagaaagtg aaggaagtgg
    11041 tggcaggcgg acaaatccag tccggctatt atcaattgcc ccagctaaaa gaagatgtca
    11101 accggttcat cctgttcaaa accggtaaaa aaggctcggc taccctgatt tacatcgagg
    11161 gcgagttgga tgcagacgat ctggtaacca tgttatttat gaaaaaaaac taaacattat
    11221 aagaatatga aacacattta tttattactg tttatgctga tcccgatggc gggaatggct
    11281 caagaaggca tttcgcaaga cacgactctt tacgtcaacg gacgcaaaat cctgattaaa
    11341 gaaaacgaag ggaaaataaa ggtaaaactt tacgaacagt cttcgcacgg cgatacgata
    11401 gagaacgatc agatttttga gggaatctat acggacggac aaaccaccga acgccgcacg
    11461 gcattcaccg tccccttcgt caaaagaaag aaccattatc ggttcgaccc gcatattgcc
    11521 ggattctata tgggatacac acggctctct gacggcatca acttcaatac tccggacgga
    11581 ctgaatataa acgccaacaa gtcctgggaa atcggtttca atctgtttca aggctccctg
    11641 acactctcac gtgatcgcca atggggcata acgaccggtt taggctgggg ataccgctct
    11701 ttccgcctgg gcaacaacta tgccttcaga caaatagatg gagtcaccgg cattgttccg
    11761 ggtgttcccg acgaggaagt gtataccaaa agccggttac gctatttcta cttccgcatt
    11821 ccggtagccc tggaatggca aaaaagattc agccacagca atgctcacgg tcctctattc
    11881 ttttcagccg gacttgaagc ggaaatccgt catggggcta agtcgaaagc aaaggtcaac
    11941 ggacataaaa agaacctgga cagtgacctg aatgtccacc cggtaggcat taacctcctg
    12001 gcacaagcag gttacggtga catcggagtg tatttgcgct actctaccta cagcctcttc
    12061 gaacacaaaa aacggtcccg aactttatcc ctactctttc ggtctgtgct ggtattggta
    12121 acaggaagcc cgacggatgg caaccataca cccggccgac ggcatcaaca gtccgactat
    12181 tcaaaaacga taagctgatt tc
//
