## Fri May 2 00:50:11 2025 ## emapper-2.1.12 ## /home/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /home/m128030022/prbbiotics_cp/prokka_results/GCA_003970855.1/GCA_003970855.1.faa --temp_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_003970855.1/2.eggNOGmapper --output_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_003970855.1/2.eggNOGmapper --output eggNOG_out --override --cpu 14 -m diamond --sensmode fast ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs JIJKFJGP_00001 552531.BIF_01514 0.0 1007.0 COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,4CZHK@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - iNJ661.Rv2992c tRNA-synt_1c JIJKFJGP_00004 552531.BIF_01513 0.0 871.0 COG1409@1|root,COG1409@2|Bacteria,2HRDZ@201174|Actinobacteria,4CYQR@85004|Bifidobacteriales 201174|Actinobacteria S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos JIJKFJGP_00005 552531.BIF_01512 1.96e-186 519.0 COG1414@1|root,COG1414@2|Bacteria,2GKB0@201174|Actinobacteria,4CZ9D@85004|Bifidobacteriales 201174|Actinobacteria K Transcriptional regulator, IclR family, C-terminal domain protein ltbR - - - - - - - - - - - HTH_IclR,IclR JIJKFJGP_00006 35760.BCHO_0277 0.0 898.0 COG0065@1|root,COG0065@2|Bacteria,2GKT7@201174|Actinobacteria,4CYUC@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase JIJKFJGP_00007 552531.BIF_01510 8.41e-165 460.0 COG0066@1|root,COG0066@2|Bacteria,2GJ8Z@201174|Actinobacteria,4CZ2F@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C JIJKFJGP_00008 552531.BIF_01509 5.98e-55 172.0 COG1522@1|root,COG1522@2|Bacteria,2IQD4@201174|Actinobacteria,4D1AW@85004|Bifidobacteriales 201174|Actinobacteria K Lrp/AsnC ligand binding domain - - - - - - - - - - - - AsnC_trans_reg JIJKFJGP_00009 552531.BIF_01083 0.0 891.0 COG0446@1|root,COG0446@2|Bacteria,2H7WY@201174|Actinobacteria,4CZXP@85004|Bifidobacteriales 201174|Actinobacteria C Pyridine nucleotide-disulphide oxidoreductase nox - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim,Reductase_C JIJKFJGP_00010 1690.BPSG_1309 4.71e-316 861.0 COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4CZN7@85004|Bifidobacteriales 201174|Actinobacteria M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase JIJKFJGP_00011 35760.BCHO_0282 1.57e-202 565.0 COG0204@1|root,COG0204@2|Bacteria,2GKVA@201174|Actinobacteria,4CZG0@85004|Bifidobacteriales 201174|Actinobacteria I Phosphate acyltransferases plsC2 - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase JIJKFJGP_00012 35760.BCHO_0283 1.02e-202 565.0 COG0240@1|root,COG0240@2|Bacteria,2GJSD@201174|Actinobacteria,4CZHP@85004|Bifidobacteriales 201174|Actinobacteria I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N JIJKFJGP_00013 552531.BIF_01368 2.54e-278 761.0 COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria,4CZ1R@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the D-alanine--D-alanine ligase family ddl GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N JIJKFJGP_00015 552531.BIF_01367 3.07e-178 507.0 29W7E@1|root,30HSM@2|Bacteria,2HZTK@201174|Actinobacteria,4D1PX@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4854) - - - - - - - - - - - - DUF4854 JIJKFJGP_00016 552531.BIF_01450 1.65e-236 654.0 COG1266@1|root,COG1266@2|Bacteria,2I3DW@201174|Actinobacteria,4CZJZ@85004|Bifidobacteriales 201174|Actinobacteria S CAAX protease self-immunity - - - - - - - - - - - - Abi JIJKFJGP_00017 552531.BIF_01449 2.29e-186 519.0 COG0668@1|root,COG0668@2|Bacteria,2GZI1@201174|Actinobacteria,4CZ0A@85004|Bifidobacteriales 201174|Actinobacteria M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel,cNMP_binding JIJKFJGP_00018 552531.BIF_01448 9.92e-149 418.0 COG1309@1|root,COG1309@2|Bacteria,2I8SX@201174|Actinobacteria,4CZXQ@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N JIJKFJGP_00019 552531.BIF_01447 5.91e-297 810.0 COG1073@1|root,COG1073@2|Bacteria,2GMT6@201174|Actinobacteria,4CZ4Q@85004|Bifidobacteriales 201174|Actinobacteria S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - DUF2974 JIJKFJGP_00020 552531.BIF_01445 1.12e-209 579.0 COG4905@1|root,COG4905@2|Bacteria,2IA3M@201174|Actinobacteria,4CZY7@85004|Bifidobacteriales 201174|Actinobacteria S Putative ABC-transporter type IV - - - - - - - - - - - - ABC_trans_CmpB JIJKFJGP_00021 552531.BIF_01444 1.27e-291 795.0 COG0436@1|root,COG0436@2|Bacteria,2GPM3@201174|Actinobacteria,4CZ6T@85004|Bifidobacteriales 201174|Actinobacteria E Psort location Cytoplasmic, score 8.87 - - 2.6.1.1 ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 JIJKFJGP_00022 552531.BIF_00027 0.0 1860.0 COG0457@1|root,COG0457@2|Bacteria,2I8FI@201174|Actinobacteria,4CZDI@85004|Bifidobacteriales 201174|Actinobacteria S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - TPR_8 JIJKFJGP_00023 552531.BIF_00084 0.0 1058.0 COG0457@1|root,COG0457@2|Bacteria,2I8FI@201174|Actinobacteria,4CZDI@85004|Bifidobacteriales 201174|Actinobacteria S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - TPR_8 JIJKFJGP_00024 552531.BIF_01945 3.96e-253 694.0 COG0524@1|root,COG0524@2|Bacteria,2IA3T@201174|Actinobacteria,4CYSM@85004|Bifidobacteriales 201174|Actinobacteria G pfkB family carbohydrate kinase - - - - - - - - - - - - ADP_ribosyl_GH,PfkB JIJKFJGP_00025 552531.BIF_01946 3.36e-42 137.0 COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria,4D17Q@85004|Bifidobacteriales 201174|Actinobacteria J Ribosomal L28 family rpmB GO:0003674,GO:0003735,GO:0005198 - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 JIJKFJGP_00026 552531.BIF_00398 0.0 1554.0 COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria,4CYTV@85004|Bifidobacteriales 201174|Actinobacteria L helicase superfamily c-terminal domain recG GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge,tRNA_anti-codon JIJKFJGP_00027 552531.BIF_01178 0.0 5302.0 COG2304@1|root,COG4932@1|root,COG2304@2|Bacteria,COG4932@2|Bacteria,2H2BH@201174|Actinobacteria,4D2YF@85004|Bifidobacteriales 201174|Actinobacteria M Spy0128-like isopeptide containing domain - - - - - - - - - - - - DUF11,FctA,VWA_2 JIJKFJGP_00028 552531.BIF_01531 1.17e-131 374.0 COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria,4D0GU@85004|Bifidobacteriales 201174|Actinobacteria L Conserved hypothetical protein 95 rsmD - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 JIJKFJGP_00029 552531.BIF_01530 1.47e-203 562.0 COG0336@1|root,COG0336@2|Bacteria,2GJ1G@201174|Actinobacteria,4CZ7A@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - Acetyltransf_1,tRNA_m1G_MT JIJKFJGP_00030 552531.BIF_01529 7.44e-155 434.0 COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria,4D0C6@85004|Bifidobacteriales 201174|Actinobacteria J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM GO:0008150,GO:0040007 - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM JIJKFJGP_00031 552531.BIF_01528 4.08e-62 190.0 COG1837@1|root,COG1837@2|Bacteria,2IQ4C@201174|Actinobacteria,4D16Z@85004|Bifidobacteriales 201174|Actinobacteria S Belongs to the UPF0109 family - GO:0008150,GO:0040007 - ko:K06960 - - - - ko00000 - - - KH_4 JIJKFJGP_00032 552531.BIF_01527 8.95e-94 275.0 COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,4D0PE@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 JIJKFJGP_00033 552531.BIF_01526 0.0 2385.0 COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,4CYYS@85004|Bifidobacteriales 201174|Actinobacteria G Psort location Cytoplasmic, score 8.87 lacZ - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N JIJKFJGP_00034 552531.BIF_01525 8.36e-283 773.0 COG3021@1|root,COG3021@2|Bacteria,2GK2H@201174|Actinobacteria,4CYS3@85004|Bifidobacteriales 201174|Actinobacteria S Endonuclease/Exonuclease/phosphatase family - - - - - - - - - - - - Exo_endo_phos JIJKFJGP_00035 552531.BIF_00240 1.62e-205 571.0 COG3965@1|root,COG3965@2|Bacteria,2H4CC@201174|Actinobacteria,4CZ1H@85004|Bifidobacteriales 201174|Actinobacteria P Cation efflux family - - - - - - - - - - - - Cation_efflux JIJKFJGP_00036 552531.BIF_00707 0.0 958.0 COG0541@1|root,COG0541@2|Bacteria,2GK4R@201174|Actinobacteria,4CYY1@85004|Bifidobacteriales 201174|Actinobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ffh GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB JIJKFJGP_00037 552531.BIF_00811 0.0 1107.0 COG0215@1|root,COG0215@2|Bacteria,2GJF2@201174|Actinobacteria,4CZZ9@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e JIJKFJGP_00038 552531.BIF_00812 0.0 1418.0 COG0488@1|root,COG0488@2|Bacteria,2GJ5M@201174|Actinobacteria,4CZCU@85004|Bifidobacteriales 201174|Actinobacteria S ABC transporter yjjK - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn JIJKFJGP_00039 552531.BIF_00816 6.62e-176 490.0 COG0518@1|root,COG0518@2|Bacteria,2GNA6@201174|Actinobacteria,4CYR4@85004|Bifidobacteriales 201174|Actinobacteria F Peptidase C26 - - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,Methyltransf_11 JIJKFJGP_00040 552531.BIF_01769 1.08e-119 343.0 COG0440@1|root,COG0440@2|Bacteria,2GJCH@201174|Actinobacteria,4CYXX@85004|Bifidobacteriales 201174|Actinobacteria E ACT domain ilvN GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - ACT,ACT_5,ALS_ss_C JIJKFJGP_00041 552531.BIF_00863 0.0 1325.0 COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4CYR0@85004|Bifidobacteriales 201174|Actinobacteria H Thiamine pyrophosphate enzyme, central domain ilvB - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N JIJKFJGP_00042 552531.BIF_01247 3.18e-181 505.0 COG0571@1|root,COG0571@2|Bacteria,2GKER@201174|Actinobacteria,4CZ98@85004|Bifidobacteriales 201174|Actinobacteria J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm JIJKFJGP_00043 552531.BIF_01883 4.3e-40 132.0 COG0333@1|root,COG0333@2|Bacteria,2GQP3@201174|Actinobacteria,4D18N@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the bacterial ribosomal protein bL32 family rpmF - - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p JIJKFJGP_00044 552531.BIF_01248 1.08e-144 407.0 COG1399@1|root,COG1399@2|Bacteria,2GJTS@201174|Actinobacteria,4CZ0J@85004|Bifidobacteriales 201174|Actinobacteria S Uncharacterized ACR, COG1399 - GO:0008150,GO:0040007 - ko:K07040 - - - - ko00000 - - - DUF177 JIJKFJGP_00045 552531.BIF_01249 1.03e-156 441.0 2EKTZ@1|root,33EHP@2|Bacteria,2HZD3@201174|Actinobacteria,4CZV9@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00046 552531.BIF_01250 2.39e-113 325.0 COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,4CYR5@85004|Bifidobacteriales 201174|Actinobacteria H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like JIJKFJGP_00047 552531.BIF_01882 2.64e-67 203.0 2CAFG@1|root,32ZDZ@2|Bacteria,2I800@201174|Actinobacteria,4D107@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3039) - - - - - - - - - - - - DUF3039 JIJKFJGP_00048 552531.BIF_01306 1.73e-248 681.0 COG0667@1|root,COG0667@2|Bacteria,2GMT5@201174|Actinobacteria,4CZ25@85004|Bifidobacteriales 201174|Actinobacteria C Aldo/keto reductase family - - - ko:K19265 - - - - ko00000,ko01000 - - - Aldo_ket_red JIJKFJGP_00049 552531.BIF_01305 0.0 868.0 COG1488@1|root,COG1488@2|Bacteria,2GJAT@201174|Actinobacteria,4CYUR@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - NAPRTase JIJKFJGP_00050 35760.BCHO_0906 8.13e-59 191.0 2DR9G@1|root,33ASJ@2|Bacteria,2I45M@201174|Actinobacteria,4D2WG@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00051 552531.BIF_01303 1.69e-174 486.0 COG0689@1|root,COG0689@2|Bacteria,2GJFI@201174|Actinobacteria,4CZBF@85004|Bifidobacteriales 201174|Actinobacteria J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - RNase_PH,RNase_PH_C JIJKFJGP_00052 552531.BIF_01302 2.59e-170 475.0 COG0127@1|root,COG0127@2|Bacteria,2GM2B@201174|Actinobacteria,4CZ3F@85004|Bifidobacteriales 201174|Actinobacteria F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like JIJKFJGP_00053 552531.BIF_00564 2.98e-313 853.0 COG2348@1|root,COG2348@2|Bacteria,2HZ91@201174|Actinobacteria,4CYZJ@85004|Bifidobacteriales 201174|Actinobacteria V Psort location Cytoplasmic, score 8.87 - - - ko:K12554 ko00550,ko01100,map00550,map01100 - R08780 RC00055,RC00064 ko00000,ko00001,ko01000,ko01011 - - - FemAB JIJKFJGP_00054 552531.BIF_01160 3.86e-236 650.0 COG0679@1|root,COG0679@2|Bacteria,2GN0R@201174|Actinobacteria,4CZ6C@85004|Bifidobacteriales 201174|Actinobacteria S Auxin Efflux Carrier - - - ko:K07088 - - - - ko00000 - - - Mem_trans JIJKFJGP_00057 552531.BIF_01161 4.94e-287 784.0 COG0836@1|root,COG0836@2|Bacteria,2GIRM@201174|Actinobacteria,4CZMK@85004|Bifidobacteriales 201174|Actinobacteria M Mannose-6-phosphate isomerase manC - 2.7.7.13 ko:K00971 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 M00114,M00361,M00362 R00885 RC00002 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase JIJKFJGP_00058 552531.BIF_02104 0.0 1136.0 COG0166@1|root,COG0166@2|Bacteria,2GJG0@201174|Actinobacteria,4CYVV@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the GPI family pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI JIJKFJGP_00059 552531.BIF_01142 1.67e-79 236.0 COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4D0V2@85004|Bifidobacteriales 201174|Actinobacteria J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 JIJKFJGP_00060 552531.BIF_01141 3.61e-175 489.0 COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria,4CZEY@85004|Bifidobacteriales 201174|Actinobacteria U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 JIJKFJGP_00061 552531.BIF_02105 5.07e-185 515.0 COG0164@1|root,COG0164@2|Bacteria,2GJFN@201174|Actinobacteria,4CZ1U@85004|Bifidobacteriales 201174|Actinobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII JIJKFJGP_00062 552531.BIF_01139 1.28e-229 632.0 COG1136@1|root,COG1136@2|Bacteria,2GM25@201174|Actinobacteria,4D0FV@85004|Bifidobacteriales 201174|Actinobacteria V ATPases associated with a variety of cellular activities lolD - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran JIJKFJGP_00063 552531.BIF_00958 0.0 885.0 COG0577@1|root,COG0577@2|Bacteria,2GKF3@201174|Actinobacteria,4D03X@85004|Bifidobacteriales 201174|Actinobacteria V Efflux ABC transporter, permease protein - - - - - - - - - - - - FtsX JIJKFJGP_00064 78346.BRUM_0635 3.25e-155 443.0 COG0679@1|root,COG0679@2|Bacteria,2GNIA@201174|Actinobacteria,4CZFX@85004|Bifidobacteriales 201174|Actinobacteria S Transporter, auxin efflux carrier (AEC) family protein - - - ko:K07088 - - - - ko00000 - - - Mem_trans JIJKFJGP_00065 552531.BIF_02106 5.31e-295 820.0 COG0624@1|root,COG0624@2|Bacteria,2GK09@201174|Actinobacteria,4CZ9K@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase dimerisation domain dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 JIJKFJGP_00066 552531.BIF_00201 0.0 1558.0 COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,4CYQT@85004|Bifidobacteriales 201174|Actinobacteria J Ribonuclease E/G family rne - 3.1.26.12 ko:K08300,ko:K08301 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - IF2_N,RNase_E_G,S1 JIJKFJGP_00067 552531.BIF_00413 7.1e-62 190.0 COG0261@1|root,COG0261@2|Bacteria,2IQ9A@201174|Actinobacteria,4D10B@85004|Bifidobacteriales 201174|Actinobacteria J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p JIJKFJGP_00068 552531.BIF_01950 1.23e-52 165.0 COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,4D19N@85004|Bifidobacteriales 201174|Actinobacteria J Ribosomal L27 protein rpmA GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 JIJKFJGP_00069 35760.BCHO_0931 0.0 939.0 COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,4CYWD@85004|Bifidobacteriales 201174|Actinobacteria S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - DUF1967,GTP1_OBG,MMR_HSR1 JIJKFJGP_00070 552531.BIF_01459 1.76e-261 717.0 COG0263@1|root,COG0263@2|Bacteria,2GM8U@201174|Actinobacteria,4CZ2B@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA JIJKFJGP_00071 552531.BIF_01460 2.39e-295 805.0 COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4CZFY@85004|Bifidobacteriales 201174|Actinobacteria E DegT/DnrJ/EryC1/StrS aminotransferase family aspC - 2.6.1.1,2.6.1.2,2.6.1.66 ko:K00812,ko:K08969,ko:K10907,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00034 R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052,R07396 RC00006,RC00008,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 JIJKFJGP_00073 552531.BIF_01461 5.51e-46 148.0 COG0690@1|root,COG0690@2|Bacteria,2HZQC@201174|Actinobacteria,4D18K@85004|Bifidobacteriales 201174|Actinobacteria U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE - - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE JIJKFJGP_00074 552531.BIF_01462 3.74e-204 568.0 COG0250@1|root,COG0250@2|Bacteria,2GJFW@201174|Actinobacteria,4CYSH@85004|Bifidobacteriales 201174|Actinobacteria K Participates in transcription elongation, termination and antitermination nusG GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - NusG JIJKFJGP_00075 552531.BIF_01463 3.53e-92 275.0 COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria,4D0PA@85004|Bifidobacteriales 201174|Actinobacteria J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N JIJKFJGP_00076 552531.BIF_01464 2.3e-159 447.0 COG0081@1|root,COG0081@2|Bacteria,2GM51@201174|Actinobacteria,4CZFR@85004|Bifidobacteriales 201174|Actinobacteria J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 JIJKFJGP_00077 552531.BIF_01465 8.38e-188 521.0 COG2508@1|root,COG2508@2|Bacteria,2GN0S@201174|Actinobacteria,4CYXU@85004|Bifidobacteriales 201174|Actinobacteria QT PucR C-terminal helix-turn-helix domain - - - - - - - - - - - - HTH_30 JIJKFJGP_00078 552531.BIF_01466 2.36e-216 597.0 COG0340@1|root,COG0340@2|Bacteria,2GN8Q@201174|Actinobacteria,4D0R8@85004|Bifidobacteriales 201174|Actinobacteria H Biotin/lipoate A/B protein ligase family birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB JIJKFJGP_00079 552531.BIF_01200 4.06e-134 383.0 COG1268@1|root,COG1268@2|Bacteria,2GJ53@201174|Actinobacteria,4D0BB@85004|Bifidobacteriales 201174|Actinobacteria S BioY family bioY - - ko:K03523 ko02010,map02010 M00581,M00582 - - ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 - - BioY JIJKFJGP_00080 552531.BIF_01199 0.0 1249.0 COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4CYU4@85004|Bifidobacteriales 201174|Actinobacteria I Carbamoyl-phosphate synthase L chain, ATP binding domain protein accC - 6.3.4.14,6.4.1.2,6.4.1.3 ko:K11263 ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00741 R00742,R01859,R04385 RC00040,RC00097,RC00253,RC00367,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 JIJKFJGP_00081 552531.BIF_01198 0.0 1060.0 COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CYSI@85004|Bifidobacteriales 201174|Actinobacteria I Carboxyl transferase domain pccB - - - - - - - - - - - Carboxyl_trans JIJKFJGP_00082 552531.BIF_00783 0.0 6047.0 COG0304@1|root,COG0331@1|root,COG2030@1|root,COG4981@1|root,COG0304@2|Bacteria,COG0331@2|Bacteria,COG2030@2|Bacteria,COG4981@2|Bacteria,2GIY4@201174|Actinobacteria,4CYXJ@85004|Bifidobacteriales 201174|Actinobacteria I Beta-ketoacyl synthase, C-terminal domain fas - - ko:K11533 ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931 M00082,M00083 R01624,R01626,R04355,R04428,R04429,R04533,R04534,R04535,R04536,R04537,R04543,R04544,R04566,R04568,R04724,R04726,R04952,R04953,R04954,R04955,R04957,R04958,R04960,R04961,R04963,R04964,R04965,R04966,R04968,R04969,R07762,R07763,R07764,R07765,R10700 RC00004,RC00029,RC00039,RC00052,RC00076,RC00117,RC00831,RC01095,RC02727,RC02728,RC02729,RC02857,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1,DUF1729,Ketoacyl-synt_C,MaoC_dehydratas,SAT,ketoacyl-synt JIJKFJGP_00083 552531.BIF_00819 1.39e-102 298.0 COG0736@1|root,COG0736@2|Bacteria,2HZNB@201174|Actinobacteria,4D10J@85004|Bifidobacteriales 201174|Actinobacteria I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS JIJKFJGP_00085 552531.BIF_02221 4.41e-156 439.0 2B37S@1|root,31VVT@2|Bacteria,2IDBE@201174|Actinobacteria,4CZJV@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00086 552531.BIF_00419 2.28e-238 656.0 COG0039@1|root,COG0039@2|Bacteria,2IASS@201174|Actinobacteria,4CZRT@85004|Bifidobacteriales 201174|Actinobacteria C Belongs to the LDH MDH superfamily ldh - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N JIJKFJGP_00087 552531.BIF_00418 2.28e-65 199.0 COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4D10E@85004|Bifidobacteriales 201174|Actinobacteria J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 JIJKFJGP_00088 552531.BIF_00099 0.0 1563.0 COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria,4CYSW@85004|Bifidobacteriales 201174|Actinobacteria J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 JIJKFJGP_00089 552531.BIF_02222 2.65e-128 365.0 COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria,4CZE2@85004|Bifidobacteriales 201174|Actinobacteria S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA JIJKFJGP_00090 552531.BIF_01347 0.0 1311.0 COG4907@1|root,COG4907@2|Bacteria,2HZD2@201174|Actinobacteria,4CZV5@85004|Bifidobacteriales 201174|Actinobacteria S Predicted membrane protein (DUF2207) - - - - - - - - - - - - DUF2207 JIJKFJGP_00091 552531.BIF_01348 2.7e-237 652.0 COG0208@1|root,COG0208@2|Bacteria,2GK46@201174|Actinobacteria,4CYQ2@85004|Bifidobacteriales 201174|Actinobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0090304,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_sm JIJKFJGP_00092 552531.BIF_01349 0.0 1415.0 COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4CZF3@85004|Bifidobacteriales 201174|Actinobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdE GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005971,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0016728,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0051063,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0071944,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN JIJKFJGP_00093 552531.BIF_01350 2.38e-100 295.0 COG1780@1|root,COG1780@2|Bacteria,2IM4D@201174|Actinobacteria,4D0XV@85004|Bifidobacteriales 201174|Actinobacteria F Probably involved in ribonucleotide reductase function nrdI - - ko:K03647 - - - - ko00000 - - - Flavodoxin_NdrI JIJKFJGP_00094 35760.BCHO_0957 7.35e-28 104.0 COG0695@1|root,COG0695@2|Bacteria,2IRCP@201174|Actinobacteria,4D17U@85004|Bifidobacteriales 201174|Actinobacteria O Glutaredoxin nrdH - - ko:K06191 - - - - ko00000 - - - Glutaredoxin JIJKFJGP_00095 552531.BIF_00226 5.57e-214 590.0 COG0667@1|root,COG0667@2|Bacteria,2GJ6R@201174|Actinobacteria,4CZB6@85004|Bifidobacteriales 201174|Actinobacteria C Oxidoreductase, aldo keto reductase family protein - - - - - - - - - - - - Aldo_ket_red JIJKFJGP_00096 552531.BIF_00913 0.0 1032.0 COG0826@1|root,COG0826@2|Bacteria,2GKTB@201174|Actinobacteria,4CZA1@85004|Bifidobacteriales 201174|Actinobacteria O Peptidase family U32 C-terminal domain - - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32,Peptidase_U32_C JIJKFJGP_00097 552531.BIF_00523 1.79e-288 788.0 COG1496@1|root,COG1496@2|Bacteria,2GN1M@201174|Actinobacteria,4CZBI@85004|Bifidobacteriales 201174|Actinobacteria Q Multi-copper polyphenol oxidoreductase laccase yfiH GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944 - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 JIJKFJGP_00098 552531.BIF_00524 3.41e-193 536.0 COG1211@1|root,COG1211@2|Bacteria,2GNHP@201174|Actinobacteria,4CYVZ@85004|Bifidobacteriales 201174|Actinobacteria I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) ispD - 1.1.1.405,2.7.7.40,2.7.7.60 ko:K00991,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 M00096 R01525,R02921,R05633 RC00002,RC00089 ko00000,ko00001,ko00002,ko01000 - - - IspD,adh_short JIJKFJGP_00099 552531.BIF_00158 2.7e-172 480.0 COG2039@1|root,COG2039@2|Bacteria,2GN39@201174|Actinobacteria,4CZ57@85004|Bifidobacteriales 201174|Actinobacteria O Removes 5-oxoproline from various penultimate amino acid residues except L-proline pcp - 3.4.19.3 ko:K01304 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C15 JIJKFJGP_00100 552531.BIF_00558 3.73e-192 558.0 COG1196@1|root,COG1196@2|Bacteria,2HZ99@201174|Actinobacteria,4CZ0S@85004|Bifidobacteriales 201174|Actinobacteria D nuclear chromosome segregation - - - - - - - - - - - - DivIVA JIJKFJGP_00101 552531.BIF_00088 0.0 927.0 COG3579@1|root,COG3579@2|Bacteria,2GNYU@201174|Actinobacteria,4CZDZ@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase C1-like family pepC2 - 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 JIJKFJGP_00102 552531.BIF_02096 8.35e-279 761.0 COG0722@1|root,COG0722@2|Bacteria,2GMVF@201174|Actinobacteria,4CZMR@85004|Bifidobacteriales 201174|Actinobacteria E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroG - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 JIJKFJGP_00103 552531.BIF_00691 0.0 1392.0 COG1835@1|root,COG1835@2|Bacteria,2GKI5@201174|Actinobacteria,4D0BY@85004|Bifidobacteriales 201174|Actinobacteria I Psort location CytoplasmicMembrane, score 9.99 - - - - - - - - - - - - Acyl_transf_3 JIJKFJGP_00104 552531.BIF_02097 1.15e-305 833.0 COG0722@1|root,COG0722@2|Bacteria,2GMVF@201174|Actinobacteria,4CZ7I@85004|Bifidobacteriales 201174|Actinobacteria E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroG - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 JIJKFJGP_00105 552531.BIF_01100 2.15e-155 437.0 COG0775@1|root,COG0775@2|Bacteria,2I8GZ@201174|Actinobacteria,4CYTM@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively mtnN - 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 JIJKFJGP_00106 552531.BIF_01099 1.85e-280 768.0 COG5002@1|root,COG5002@2|Bacteria,2GJY7@201174|Actinobacteria,4CZ42@85004|Bifidobacteriales 201174|Actinobacteria T His Kinase A (phosphoacceptor) domain phoR - 2.7.13.3 ko:K07636,ko:K07768 ko02020,map02020 M00434,M00443 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS_4 JIJKFJGP_00107 552531.BIF_01098 1.32e-168 471.0 COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4CZTX@85004|Bifidobacteriales 201174|Actinobacteria KT Transcriptional regulatory protein, C terminal regX3 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - ko:K07776 ko02020,map02020 M00443 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C JIJKFJGP_00108 552531.BIF_01097 3.8e-262 719.0 COG0226@1|root,COG0226@2|Bacteria,2GJXD@201174|Actinobacteria,4CYTZ@85004|Bifidobacteriales 201174|Actinobacteria P Part of the ABC transporter complex PstSACB involved in phosphate import pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 JIJKFJGP_00109 552531.BIF_01096 2.63e-218 604.0 COG0573@1|root,COG0573@2|Bacteria,2GJDA@201174|Actinobacteria,4CYV0@85004|Bifidobacteriales 201174|Actinobacteria P probably responsible for the translocation of the substrate across the membrane pstC - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 JIJKFJGP_00110 552531.BIF_00309 1.53e-221 612.0 COG0581@1|root,COG0581@2|Bacteria,2I2F2@201174|Actinobacteria,4D2UW@85004|Bifidobacteriales 201174|Actinobacteria P Phosphate transport system permease pstA - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 JIJKFJGP_00111 552531.BIF_00142 1.51e-188 523.0 COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4CYVE@85004|Bifidobacteriales 201174|Actinobacteria P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran JIJKFJGP_00112 552531.BIF_01233 0.0 869.0 COG2252@1|root,COG2252@2|Bacteria,2GKYD@201174|Actinobacteria,4CZHD@85004|Bifidobacteriales 201174|Actinobacteria S Permease family - - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease JIJKFJGP_00113 552531.BIF_01234 2.41e-210 582.0 COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria,4CZ99@85004|Bifidobacteriales 201174|Actinobacteria P Zinc-uptake complex component A periplasmic - - - ko:K02077 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ZnuA JIJKFJGP_00114 552531.BIF_01235 2.13e-114 330.0 COG0244@1|root,COG0244@2|Bacteria,2GM0V@201174|Actinobacteria,4CZFP@85004|Bifidobacteriales 201174|Actinobacteria J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 JIJKFJGP_00115 552531.BIF_01236 9.38e-68 207.0 COG0222@1|root,COG0222@2|Bacteria,2IKNW@201174|Actinobacteria,4D0W2@85004|Bifidobacteriales 201174|Actinobacteria J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N JIJKFJGP_00116 552531.BIF_01238 0.0 1031.0 COG1716@1|root,COG1716@2|Bacteria,2GIT6@201174|Actinobacteria,4CYX9@85004|Bifidobacteriales 201174|Actinobacteria T Forkhead associated domain - - - - - - - - - - - - FHA JIJKFJGP_00117 552531.BIF_01379 0.0 2348.0 COG1112@1|root,COG1112@2|Bacteria,2GKJW@201174|Actinobacteria,4CYY9@85004|Bifidobacteriales 201174|Actinobacteria L Superfamily I DNA and RNA helicases and helicase subunits - - - - - - - - - - - - AAA_11,AAA_12,DUF4011 JIJKFJGP_00118 552531.BIF_01378 2.19e-52 165.0 2B18D@1|root,31TNU@2|Bacteria,2GSR6@201174|Actinobacteria,4D1ET@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00119 552531.BIF_01377 8.73e-132 375.0 COG1261@1|root,COG1261@2|Bacteria,2IIYF@201174|Actinobacteria,4D0YD@85004|Bifidobacteriales 201174|Actinobacteria NO SAF - - - - - - - - - - - - ChapFlgA,SAF JIJKFJGP_00120 552531.BIF_01376 1.76e-43 140.0 COG2331@1|root,COG2331@2|Bacteria,2IQHE@201174|Actinobacteria,4D1ES@85004|Bifidobacteriales 201174|Actinobacteria S Putative regulatory protein - - - - - - - - - - - - Zn-ribbon_8 JIJKFJGP_00121 552531.BIF_02098 1.84e-177 504.0 COG0212@1|root,COG0212@2|Bacteria,2IKWR@201174|Actinobacteria,4D12B@85004|Bifidobacteriales 201174|Actinobacteria H 5-formyltetrahydrofolate cyclo-ligase family ygfA - 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig JIJKFJGP_00122 1688.BCUN_1232 1.59e-103 305.0 COG1670@1|root,COG1670@2|Bacteria,2HAFI@201174|Actinobacteria,4CZRR@85004|Bifidobacteriales 201174|Actinobacteria J Acetyltransferase (GNAT) domain rimJ - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 JIJKFJGP_00123 552531.BIF_01374 1.73e-257 710.0 2E03N@1|root,32VSG@2|Bacteria,2GQE4@201174|Actinobacteria,4CYUX@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00124 552531.BIF_00675 4.55e-64 195.0 COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4D101@85004|Bifidobacteriales 201174|Actinobacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 JIJKFJGP_00128 552531.BIF_00677 2.06e-35 120.0 COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria,4D1EA@85004|Bifidobacteriales 201174|Actinobacteria J Ribosomal protein L33 rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 JIJKFJGP_00129 552531.BIF_00678 2.74e-302 825.0 COG0812@1|root,COG0812@2|Bacteria,2GIV2@201174|Actinobacteria,4CZSJ@85004|Bifidobacteriales 201174|Actinobacteria M Cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C JIJKFJGP_00130 552531.BIF_00933 0.0 1000.0 COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,4CYZA@85004|Bifidobacteriales 201174|Actinobacteria E aromatic amino acid transport protein AroP K03293 - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 JIJKFJGP_00131 552531.BIF_00932 4.15e-80 236.0 COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,4D11B@85004|Bifidobacteriales 201174|Actinobacteria C 4Fe-4S binding domain fdxA GO:0001666,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0036293,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0075136 - ko:K05524 - - - - ko00000 - - - Fer4 JIJKFJGP_00132 552531.BIF_00960 7.49e-282 769.0 COG0436@1|root,COG0436@2|Bacteria,2GJMI@201174|Actinobacteria,4CZ91@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase class I and II dapC - - - - - - - - - - - Aminotran_1_2 JIJKFJGP_00133 552531.BIF_00961 0.0 875.0 COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4CZHT@85004|Bifidobacteriales 201174|Actinobacteria L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - HHH_5,IMS,IMS_C,IMS_HHH JIJKFJGP_00135 552531.BIF_01317 1e-243 670.0 COG0111@1|root,COG0111@2|Bacteria,2GKTT@201174|Actinobacteria,4CZRS@85004|Bifidobacteriales 201174|Actinobacteria EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family pdxB - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C JIJKFJGP_00136 552531.BIF_01316 3.01e-147 415.0 COG1739@1|root,COG1739@2|Bacteria,2GMM4@201174|Actinobacteria,4CZH8@85004|Bifidobacteriales 201174|Actinobacteria S Uncharacterized protein family UPF0029 yigZ - - - - - - - - - - - DUF1949,UPF0029 JIJKFJGP_00137 552531.BIF_01315 1.73e-157 444.0 2BMRI@1|root,32GAY@2|Bacteria,2GMIA@201174|Actinobacteria,4CZFZ@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - LRV JIJKFJGP_00138 552531.BIF_01314 0.0 1483.0 COG1640@1|root,COG1640@2|Bacteria,2GM5Z@201174|Actinobacteria,4CZC7@85004|Bifidobacteriales 201174|Actinobacteria G 4-alpha-glucanotransferase malQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 JIJKFJGP_00139 552531.BIF_00272 1.31e-103 299.0 COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria,4D0PV@85004|Bifidobacteriales 201174|Actinobacteria J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 JIJKFJGP_00140 552531.BIF_00273 6.69e-97 283.0 COG0103@1|root,COG0103@2|Bacteria,2GNDY@201174|Actinobacteria,4CZ9Y@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 JIJKFJGP_00141 552531.BIF_01373 0.0 1859.0 COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,4CYZ1@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 13 family glgX - 3.2.1.196,3.2.1.68 ko:K01214,ko:K02438 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02111,R09995,R11261 - ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 JIJKFJGP_00142 552531.BIF_01372 1.65e-267 731.0 COG1940@1|root,COG1940@2|Bacteria,2I7R8@201174|Actinobacteria,4CZZ7@85004|Bifidobacteriales 201174|Actinobacteria GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565 - - - - - - - - - - - - HTH_24,MarR,ROK JIJKFJGP_00143 552531.BIF_02099 0.0 1803.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,2GJI2@201174|Actinobacteria,4CZ8F@85004|Bifidobacteriales 201174|Actinobacteria C belongs to the iron- containing alcohol dehydrogenase family adhE - 1.1.1.1,1.2.1.10,1.2.1.81 ko:K04072,ko:K15515 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 - R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 - - - Aldedh,Fe-ADH JIJKFJGP_00144 552531.BIF_00965 3.9e-244 669.0 COG5340@1|root,COG5340@2|Bacteria,2ICPH@201174|Actinobacteria,4CZJ7@85004|Bifidobacteriales 201174|Actinobacteria K Psort location Cytoplasmic, score - - - - - - - - - - - - - JIJKFJGP_00145 552531.BIF_00966 3.06e-198 548.0 28NT3@1|root,2ZBRV@2|Bacteria,2IIC3@201174|Actinobacteria,4D0MQ@85004|Bifidobacteriales 201174|Actinobacteria S YwiC-like protein - - - - - - - - - - - - YwiC JIJKFJGP_00146 1690.BPSG_0572 6.58e-68 205.0 COG0051@1|root,COG0051@2|Bacteria,2IHRA@201174|Actinobacteria,4D0UT@85004|Bifidobacteriales 201174|Actinobacteria J Involved in the binding of tRNA to the ribosomes rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 JIJKFJGP_00147 552531.BIF_00968 1.06e-153 431.0 COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria,4CYQD@85004|Bifidobacteriales 201174|Actinobacteria J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 JIJKFJGP_00148 552531.BIF_00668 3.41e-151 425.0 COG0088@1|root,COG0088@2|Bacteria,2GJYJ@201174|Actinobacteria,4CZSA@85004|Bifidobacteriales 201174|Actinobacteria J Forms part of the polypeptide exit tunnel rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 JIJKFJGP_00149 552531.BIF_00669 1.79e-61 189.0 COG0089@1|root,COG0089@2|Bacteria,2IQ7V@201174|Actinobacteria,4D11N@85004|Bifidobacteriales 201174|Actinobacteria J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 JIJKFJGP_00150 552531.BIF_00670 2.32e-196 544.0 COG0090@1|root,COG0090@2|Bacteria,2GK7R@201174|Actinobacteria,4CZ5U@85004|Bifidobacteriales 201174|Actinobacteria J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C JIJKFJGP_00151 552531.BIF_01966 6.95e-63 192.0 COG0185@1|root,COG0185@2|Bacteria,2IKMS@201174|Actinobacteria,4D105@85004|Bifidobacteriales 201174|Actinobacteria J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 JIJKFJGP_00152 552531.BIF_01965 2.68e-75 225.0 COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria,4D0UZ@85004|Bifidobacteriales 201174|Actinobacteria J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 JIJKFJGP_00153 552531.BIF_00371 2.32e-176 494.0 COG0092@1|root,COG0092@2|Bacteria,2GKF1@201174|Actinobacteria,4CYQN@85004|Bifidobacteriales 201174|Actinobacteria J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C JIJKFJGP_00154 1688.BCUN_1962 1.15e-99 288.0 COG0197@1|root,COG0197@2|Bacteria,2IFEI@201174|Actinobacteria,4D0Q8@85004|Bifidobacteriales 201174|Actinobacteria J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 JIJKFJGP_00155 552531.BIF_00369 5.27e-49 156.0 COG0255@1|root,COG0255@2|Bacteria,2IQ6V@201174|Actinobacteria,4D181@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the universal ribosomal protein uL29 family rpmC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 JIJKFJGP_00156 552531.BIF_00076 7.84e-55 171.0 COG0186@1|root,COG0186@2|Bacteria,2IQ68@201174|Actinobacteria,4D10N@85004|Bifidobacteriales 201174|Actinobacteria J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 JIJKFJGP_00157 552531.BIF_02225 5.15e-79 235.0 COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4D0VI@85004|Bifidobacteriales 201174|Actinobacteria J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 JIJKFJGP_00158 552531.BIF_01964 4.44e-68 206.0 COG0198@1|root,COG0198@2|Bacteria,2IKP2@201174|Actinobacteria,4D10I@85004|Bifidobacteriales 201174|Actinobacteria J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 JIJKFJGP_00159 552531.BIF_00213 1.94e-136 386.0 COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria,4CZCA@85004|Bifidobacteriales 201174|Actinobacteria J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C JIJKFJGP_00160 1688.BCUN_1956 4.97e-40 132.0 COG0199@1|root,COG0199@2|Bacteria,2IQ8R@201174|Actinobacteria,4D177@85004|Bifidobacteriales 201174|Actinobacteria J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 JIJKFJGP_00161 552531.BIF_00215 9.65e-91 265.0 COG0096@1|root,COG0096@2|Bacteria,2IHQZ@201174|Actinobacteria,4D0P6@85004|Bifidobacteriales 201174|Actinobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 JIJKFJGP_00162 552531.BIF_00134 6.61e-123 350.0 COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4CYQV@85004|Bifidobacteriales 201174|Actinobacteria J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 JIJKFJGP_00163 552531.BIF_00135 5.96e-77 230.0 COG0256@1|root,COG0256@2|Bacteria,2IKTX@201174|Actinobacteria,4D0WE@85004|Bifidobacteriales 201174|Actinobacteria J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p JIJKFJGP_00164 552531.BIF_00903 6.25e-132 379.0 COG0098@1|root,COG0098@2|Bacteria,2GJW8@201174|Actinobacteria,4CZCD@85004|Bifidobacteriales 201174|Actinobacteria J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C JIJKFJGP_00165 552531.BIF_01963 1.75e-33 115.0 COG1841@1|root,COG1841@2|Bacteria,2GQV0@201174|Actinobacteria,4D1EZ@85004|Bifidobacteriales 201174|Actinobacteria J Ribosomal protein L30p/L7e rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 JIJKFJGP_00166 552531.BIF_00902 3.98e-100 291.0 COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,4D0R9@85004|Bifidobacteriales 201174|Actinobacteria J binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A JIJKFJGP_00167 552531.BIF_00901 0.0 870.0 COG0201@1|root,COG0201@2|Bacteria,2GJ26@201174|Actinobacteria,4CYWU@85004|Bifidobacteriales 201174|Actinobacteria U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY JIJKFJGP_00168 552531.BIF_00325 4.41e-131 372.0 COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4CZ7Z@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid JIJKFJGP_00169 1437605.BACT_0252 4.86e-45 145.0 COG0361@1|root,COG0361@2|Bacteria,2IQ4B@201174|Actinobacteria,4D16H@85004|Bifidobacteriales 201174|Actinobacteria J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA - - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a JIJKFJGP_00170 1437605.BACT_0253 1.03e-20 81.6 COG0257@1|root,COG0257@2|Bacteria,2GWMH@201174|Actinobacteria,4D1NT@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the bacterial ribosomal protein bL36 family rpmJ - - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 JIJKFJGP_00171 552531.BIF_01157 1.17e-81 242.0 COG0099@1|root,COG0099@2|Bacteria,2IHPN@201174|Actinobacteria,4D0PQ@85004|Bifidobacteriales 201174|Actinobacteria J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 JIJKFJGP_00172 1688.BCUN_1532 1.73e-84 249.0 COG0100@1|root,COG0100@2|Bacteria,2IFFC@201174|Actinobacteria,4D0PJ@85004|Bifidobacteriales 201174|Actinobacteria J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 JIJKFJGP_00173 552531.BIF_01155 1.4e-236 650.0 COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4CZEN@85004|Bifidobacteriales 201174|Actinobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L JIJKFJGP_00174 552531.BIF_01154 1.16e-92 271.0 COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria,4D0PZ@85004|Bifidobacteriales 201174|Actinobacteria J Ribosomal protein L17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 JIJKFJGP_00175 552531.BIF_01153 6.34e-190 528.0 COG0101@1|root,COG0101@2|Bacteria,2GJ6C@201174|Actinobacteria,4CZ8H@85004|Bifidobacteriales 201174|Actinobacteria J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 JIJKFJGP_00177 552531.BIF_00443 5.94e-208 576.0 2B54U@1|root,31XYD@2|Bacteria,2HXKT@201174|Actinobacteria,4D0IH@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00178 552531.BIF_00442 6.28e-249 684.0 COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,4CYTW@85004|Bifidobacteriales 201174|Actinobacteria K Participates in both transcription termination and antitermination nusA GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - KH_5,NusA_N,S1 JIJKFJGP_00179 552531.BIF_00193 0.0 1608.0 COG0481@1|root,COG0532@1|root,COG0481@2|Bacteria,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,4CZ4B@85004|Bifidobacteriales 201174|Actinobacteria J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N JIJKFJGP_00180 552531.BIF_00219 5.79e-122 351.0 COG0858@1|root,COG0858@2|Bacteria,2IKXP@201174|Actinobacteria,4CZZZ@85004|Bifidobacteriales 201174|Actinobacteria J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA JIJKFJGP_00181 552531.BIF_00761 5.82e-250 686.0 COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,4CZED@85004|Bifidobacteriales 201174|Actinobacteria J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB_C,TruB_C_2,TruB_N JIJKFJGP_00182 552531.BIF_00762 9.91e-302 823.0 COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4CYXT@85004|Bifidobacteriales 201174|Actinobacteria H riboflavin kinase ribF GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase JIJKFJGP_00183 552531.BIF_00209 0.0 956.0 COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria,4CZE1@85004|Bifidobacteriales 201174|Actinobacteria O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI,Lon_C JIJKFJGP_00184 552531.BIF_00098 1.12e-128 369.0 2EHBK@1|root,33B3F@2|Bacteria,2ICD4@201174|Actinobacteria,4CZY5@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00185 1147128.BAST_1307 5.05e-07 46.6 29UT5@1|root,30G5G@2|Bacteria,2GXCZ@201174|Actinobacteria,4D1N2@85004|Bifidobacteriales 201174|Actinobacteria S Mitochondrial domain of unknown function (DUF1713) - - - - - - - - - - - - DUF1713 JIJKFJGP_00186 552531.BIF_00267 2.05e-164 460.0 COG0120@1|root,COG0120@2|Bacteria,2GMHW@201174|Actinobacteria,4CZDH@85004|Bifidobacteriales 201174|Actinobacteria G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A JIJKFJGP_00187 552531.BIF_01325 7.54e-240 659.0 COG0328@1|root,COG0328@2|Bacteria,2GK53@201174|Actinobacteria,4CZGC@85004|Bifidobacteriales 201174|Actinobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DUF4440,RNase_H JIJKFJGP_00189 552531.BIF_01323 2.27e-307 838.0 COG0172@1|root,COG0172@2|Bacteria,2GIWP@201174|Actinobacteria,4CZ40@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b JIJKFJGP_00190 552531.BIF_01322 1.69e-278 761.0 COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria,4CYTC@85004|Bifidobacteriales 201174|Actinobacteria I Diacylglycerol kinase catalytic domain - - - - - - - - - - - - DAGK_cat JIJKFJGP_00191 552531.BIF_01321 0.0 1144.0 COG0033@1|root,COG0033@2|Bacteria,2H1PI@201174|Actinobacteria,4CZ7X@85004|Bifidobacteriales 201174|Actinobacteria G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II pgm - 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV JIJKFJGP_00192 552531.BIF_00532 0.0 1001.0 COG1073@1|root,COG1073@2|Bacteria,2H036@201174|Actinobacteria,4CYRR@85004|Bifidobacteriales 201174|Actinobacteria S alpha beta - - - ko:K06889 - - - - ko00000 - - - BAAT_C,Hydrolase_4,Peptidase_S9 JIJKFJGP_00193 552531.BIF_01857 5.96e-146 411.0 2DM2Z@1|root,31HGC@2|Bacteria,2GKMX@201174|Actinobacteria,4CZJ9@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF4125) - - - - - - - - - - - - DUF4125 JIJKFJGP_00194 552531.BIF_00807 0.0 1390.0 COG0457@1|root,COG0457@2|Bacteria,2I7P1@201174|Actinobacteria,4CZTS@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4037) - - - - - - - - - - - - DUF4037,TPR_12 JIJKFJGP_00195 552531.BIF_01111 8.64e-163 456.0 COG2197@1|root,COG2197@2|Bacteria,2GIVA@201174|Actinobacteria,4CZW8@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, Lux Regulon tcsR3 - - - - - - - - - - - GerE,Response_reg JIJKFJGP_00196 552531.BIF_01110 0.0 931.0 COG1983@1|root,COG4585@1|root,COG1983@2|Bacteria,COG4585@2|Bacteria,2GJ4J@201174|Actinobacteria,4CZ2U@85004|Bifidobacteriales 201174|Actinobacteria KT PspC domain tcsS3 - - - - - - - - - - - HATPase_c,HATPase_c_2,PspC JIJKFJGP_00197 552531.BIF_00609 0.0 1357.0 COG1983@1|root,COG1983@2|Bacteria,2GIVS@201174|Actinobacteria,4CZZT@85004|Bifidobacteriales 201174|Actinobacteria KT PspC domain pspC - - - - - - - - - - - DUF2154,PspC JIJKFJGP_00198 552531.BIF_00200 5.45e-146 412.0 2B2J3@1|root,31V47@2|Bacteria,2GUYX@201174|Actinobacteria,4D1GQ@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00199 552531.BIF_00733 2.09e-286 782.0 COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4CZKK@85004|Bifidobacteriales 201174|Actinobacteria E Cys/Met metabolism PLP-dependent enzyme metC1 - 4.4.1.8 ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP JIJKFJGP_00200 552531.BIF_00734 2.38e-168 471.0 COG2873@1|root,COG2873@2|Bacteria,2I8JG@201174|Actinobacteria,4CZ6W@85004|Bifidobacteriales 201174|Actinobacteria E Cys/Met metabolism PLP-dependent enzyme - - 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 - R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP JIJKFJGP_00201 552531.BIF_02003 1.71e-38 129.0 COG2873@1|root,COG2873@2|Bacteria,2H9B8@201174|Actinobacteria,4D2R0@85004|Bifidobacteriales 201174|Actinobacteria E Cys/Met metabolism PLP-dependent enzyme - - - - - - - - - - - - Cys_Met_Meta_PP JIJKFJGP_00203 552531.BIF_01044 0.0 1089.0 COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria,4CZHM@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class-II aminoacyl-tRNA synthetase family lysS GO:0008150,GO:0040007 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon JIJKFJGP_00204 552531.BIF_00767 1.71e-186 526.0 29W7A@1|root,30HSH@2|Bacteria,2IQ2G@201174|Actinobacteria,4D15I@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00205 552531.BIF_00834 0.0 1002.0 COG0308@1|root,COG0308@2|Bacteria,2GP9F@201174|Actinobacteria,4CZR9@85004|Bifidobacteriales 201174|Actinobacteria E Phospholipase B - - - - - - - - - - - - Phospholip_B JIJKFJGP_00206 552531.BIF_00833 0.0 914.0 COG3579@1|root,COG3579@2|Bacteria,2HCVR@201174|Actinobacteria,4CZD8@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase C1-like family pepC - 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 JIJKFJGP_00207 552531.BIF_00164 0.0 1355.0 COG0531@1|root,COG0531@2|Bacteria,2HMMA@201174|Actinobacteria,4CZYE@85004|Bifidobacteriales 201174|Actinobacteria E Amino acid permease - - - ko:K20265 ko02024,map02024 - - - ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 - - AA_permease_2 JIJKFJGP_00208 552531.BIF_02005 0.0 1034.0 COG2939@1|root,COG2939@2|Bacteria,2GK9N@201174|Actinobacteria,4D003@85004|Bifidobacteriales 201174|Actinobacteria E Serine carboxypeptidase - - - - - - - - - - - - Peptidase_S10 JIJKFJGP_00209 552531.BIF_01128 0.0 951.0 COG0531@1|root,COG0531@2|Bacteria,2GNUF@201174|Actinobacteria,4CZBM@85004|Bifidobacteriales 201174|Actinobacteria E Amino acid permease - - - - - - - - - - - - AA_permease,AA_permease_2 JIJKFJGP_00210 31954.BPSP_0106 1.05e-101 310.0 COG1575@1|root,COG1575@2|Bacteria,2GJBS@201174|Actinobacteria,4CZHQ@85004|Bifidobacteriales 201174|Actinobacteria H Belongs to the MenA family. Type 1 subfamily menA GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA JIJKFJGP_00211 552531.BIF_01127 2.91e-179 501.0 COG0588@1|root,COG0588@2|Bacteria,2GK8F@201174|Actinobacteria,4CZMF@85004|Bifidobacteriales 201174|Actinobacteria G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmA GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 JIJKFJGP_00212 552531.BIF_00956 0.0 1468.0 COG4716@1|root,COG4716@2|Bacteria,2GKZ8@201174|Actinobacteria,4CYZK@85004|Bifidobacteriales 201174|Actinobacteria S MCRA family - - 4.2.1.53 ko:K10254 - - - - ko00000,ko01000 - - - MCRA JIJKFJGP_00213 552531.BIF_00955 1.62e-84 248.0 COG0604@1|root,COG0604@2|Bacteria,2GN47@201174|Actinobacteria,4CZA6@85004|Bifidobacteriales 201174|Actinobacteria C Zinc-binding dehydrogenase - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 JIJKFJGP_00214 552531.BIF_01403 4.64e-159 446.0 COG0604@1|root,COG0604@2|Bacteria,2GN47@201174|Actinobacteria,4CZA6@85004|Bifidobacteriales 201174|Actinobacteria C Zinc-binding dehydrogenase - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 JIJKFJGP_00215 552531.BIF_01402 0.0 973.0 COG1482@1|root,COG1482@2|Bacteria,2GJXC@201174|Actinobacteria,4CZM9@85004|Bifidobacteriales 201174|Actinobacteria G Phosphomannose isomerase type I manA - 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 - - - PMI_typeI JIJKFJGP_00216 35760.BCHO_1390 2.41e-29 107.0 2EG1H@1|root,339TH@2|Bacteria,2IQTR@201174|Actinobacteria,4D16E@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - DUF2530 JIJKFJGP_00217 552531.BIF_01401 1.87e-288 795.0 COG5002@1|root,COG5002@2|Bacteria,2GJY7@201174|Actinobacteria,4CZIM@85004|Bifidobacteriales 201174|Actinobacteria T ATPase histidine kinase DNA gyrase B HSP90 domain protein senX3 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564 2.7.13.3 ko:K07768 ko02020,map02020 M00443 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA JIJKFJGP_00218 552531.BIF_01400 4.13e-156 438.0 COG0704@1|root,COG0704@2|Bacteria,2GKAD@201174|Actinobacteria,4CZ9B@85004|Bifidobacteriales 201174|Actinobacteria P Plays a role in the regulation of phosphate uptake phoU GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0016020,GO:0019220,GO:0019222,GO:0022611,GO:0031323,GO:0031324,GO:0032502,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042221,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044444,GO:0044464,GO:0045936,GO:0046677,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:0071944,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - ko:K02039 - - - - ko00000 - - - PhoU JIJKFJGP_00219 552531.BIF_01399 2.42e-268 734.0 COG1932@1|root,COG1932@2|Bacteria,2GKYK@201174|Actinobacteria,4CZ94@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 JIJKFJGP_00220 552531.BIF_01398 1.91e-228 631.0 COG3942@1|root,COG3942@2|Bacteria,2GP2A@201174|Actinobacteria,4CYXV@85004|Bifidobacteriales 201174|Actinobacteria S CHAP domain - - - - - - - - - - - - CHAP JIJKFJGP_00221 552531.BIF_01914 1.42e-140 404.0 COG0791@1|root,COG0791@2|Bacteria,2GJX7@201174|Actinobacteria,4D01Q@85004|Bifidobacteriales 201174|Actinobacteria M NlpC/P60 family - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60,PG_binding_1,SLT JIJKFJGP_00222 552531.BIF_02006 8.87e-252 691.0 COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4CZ6V@85004|Bifidobacteriales 201174|Actinobacteria T Universal stress protein family - - - - - - - - - - - - Usp JIJKFJGP_00223 552531.BIF_02227 1.07e-94 276.0 COG1765@1|root,COG1765@2|Bacteria,2IIK7@201174|Actinobacteria,4D0PB@85004|Bifidobacteriales 201174|Actinobacteria O OsmC-like protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - OsmC JIJKFJGP_00224 552531.BIF_01243 1.12e-223 615.0 COG0207@1|root,COG0207@2|Bacteria,2GKY0@201174|Actinobacteria,4CZQ3@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt JIJKFJGP_00225 552531.BIF_01242 1.46e-170 475.0 COG0262@1|root,COG0262@2|Bacteria,2IM1S@201174|Actinobacteria,4CZM1@85004|Bifidobacteriales 201174|Actinobacteria H dihydrofolate reductase folA GO:0000166,GO:0003674,GO:0003824,GO:0004146,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070401,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv2763c DHFR_1 JIJKFJGP_00226 552531.BIF_01241 1.04e-129 368.0 COG0394@1|root,COG0394@2|Bacteria,2IM0Q@201174|Actinobacteria,4CZWM@85004|Bifidobacteriales 201174|Actinobacteria T low molecular weight ptpA GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0035335,GO:0035821,GO:0036211,GO:0042578,GO:0043170,GO:0043207,GO:0043412,GO:0044003,GO:0044046,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052046,GO:0052047,GO:0052048,GO:0052083,GO:0052155,GO:0052173,GO:0052200,GO:0052212,GO:0052255,GO:0052278,GO:0052294,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:0140096,GO:1901564 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc JIJKFJGP_00227 552531.BIF_01311 9.11e-256 700.0 COG1087@1|root,COG1087@2|Bacteria,2GMCW@201174|Actinobacteria,4CZDB@85004|Bifidobacteriales 201174|Actinobacteria M Belongs to the NAD(P)-dependent epimerase dehydratase family galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase JIJKFJGP_00228 552531.BIF_01026 5.36e-206 570.0 COG0220@1|root,COG0220@2|Bacteria,2GJ8R@201174|Actinobacteria,4CZKF@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 JIJKFJGP_00230 552531.BIF_01025 3.21e-245 674.0 COG1434@1|root,COG1434@2|Bacteria,2GMGZ@201174|Actinobacteria,4D0BS@85004|Bifidobacteriales 201174|Actinobacteria S DUF218 domain - - - - - - - - - - - - DUF218 JIJKFJGP_00231 552531.BIF_02230 1.78e-239 658.0 2BVW3@1|root,2Z7TB@2|Bacteria,2HPWM@201174|Actinobacteria,4D0NU@85004|Bifidobacteriales 201174|Actinobacteria S 5'-nucleotidase - - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5-nucleotidase JIJKFJGP_00232 552531.BIF_00720 1.95e-139 393.0 2DBP0@1|root,2ZA6P@2|Bacteria,2IHA2@201174|Actinobacteria,4D0R0@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00233 552531.BIF_01911 0.0 1009.0 COG3593@1|root,COG3593@2|Bacteria,2HZG2@201174|Actinobacteria,4D0BG@85004|Bifidobacteriales 201174|Actinobacteria L AAA ATPase domain - - - ko:K07459 - - - - ko00000 - - - AAA_15,AAA_21 JIJKFJGP_00235 552531.BIF_00662 0.0 879.0 COG4487@1|root,COG4487@2|Bacteria,2IBFR@201174|Actinobacteria,4D04Q@85004|Bifidobacteriales 201174|Actinobacteria S Uncharacterized protein conserved in bacteria (DUF2130) - - - - - - - - - - - - DUF2130 JIJKFJGP_00236 552531.BIF_00571 0.0 1018.0 2ETEZ@1|root,33KYW@2|Bacteria,2HXGA@201174|Actinobacteria,4CZSC@85004|Bifidobacteriales 201174|Actinobacteria S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - DUF3375 JIJKFJGP_00237 552531.BIF_00570 1.89e-187 521.0 2APK1@1|root,31EP8@2|Bacteria,2IEAB@201174|Actinobacteria,4D0C3@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4194) - - - - - - - - - - - - DUF4194 JIJKFJGP_00238 552531.BIF_00081 0.0 2172.0 COG4913@1|root,COG4913@2|Bacteria,2GMIP@201174|Actinobacteria,4CYWR@85004|Bifidobacteriales 201174|Actinobacteria S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - AAA_29,SbcCD_C JIJKFJGP_00239 552531.BIF_00514 7.2e-302 822.0 COG4924@1|root,COG4924@2|Bacteria,2IB33@201174|Actinobacteria,4D02A@85004|Bifidobacteriales 201174|Actinobacteria S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - DUF2220,DUF3322 JIJKFJGP_00241 552531.BIF_00312 2.83e-84 248.0 COG3189@1|root,COG3189@2|Bacteria,2IQC0@201174|Actinobacteria,4D18P@85004|Bifidobacteriales 201174|Actinobacteria K Protein of unknown function, DUF488 - - - - - - - - - - - - DUF488 JIJKFJGP_00242 552531.BIF_00311 0.0 947.0 COG2211@1|root,COG2211@2|Bacteria,2HD4Y@201174|Actinobacteria,4CZRA@85004|Bifidobacteriales 201174|Actinobacteria G Psort location CytoplasmicMembrane, score 10.00 gph - - ko:K16209 - - - - ko00000,ko02000 2.A.2.2 - - MFS_2 JIJKFJGP_00243 552531.BIF_00647 0.0 1766.0 COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,4CYYS@85004|Bifidobacteriales 201174|Actinobacteria G Psort location Cytoplasmic, score 8.87 lacZ6 - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3 JIJKFJGP_00244 552531.BIF_00912 3.44e-237 652.0 COG1609@1|root,COG1609@2|Bacteria,2H5ZG@201174|Actinobacteria,4CZ8A@85004|Bifidobacteriales 201174|Actinobacteria K Transcriptional regulator, LacI family - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 JIJKFJGP_00245 552531.BIF_00911 7.35e-152 426.0 COG1011@1|root,COG1011@2|Bacteria,2I8XE@201174|Actinobacteria,4D00B@85004|Bifidobacteriales 201174|Actinobacteria S Haloacid dehalogenase-like hydrolase - - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2,Hydrolase JIJKFJGP_00246 552531.BIF_00910 2.76e-80 241.0 2B3QQ@1|root,31WE9@2|Bacteria,2GX43@201174|Actinobacteria,4D1Q3@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00247 552531.BIF_01791 8.48e-132 374.0 2EGCD@1|root,33A46@2|Bacteria,2I2HS@201174|Actinobacteria,4D1EH@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4190) - - - - - - - - - - - - DUF4190 JIJKFJGP_00248 552531.BIF_00909 5.97e-106 306.0 2EGCD@1|root,33A46@2|Bacteria,2I2HS@201174|Actinobacteria,4D1EH@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4190) - - - - - - - - - - - - DUF4190,DUF4854 JIJKFJGP_00249 1437609.BCAL_0424 2.28e-260 721.0 COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria,4CYRE@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1,SBP_bac_8 JIJKFJGP_00250 552531.BIF_00799 0.0 1457.0 COG1874@1|root,COG1874@2|Bacteria,2GMDT@201174|Actinobacteria,4CZ38@85004|Bifidobacteriales 201174|Actinobacteria G Psort location Cytoplasmic, score 8.87 bga1 - 3.2.1.23 ko:K12308 ko00052,map00052 - R01105 RC00452 ko00000,ko00001,ko01000 - - - Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M JIJKFJGP_00251 552531.BIF_00071 7.36e-225 620.0 COG0395@1|root,COG0395@2|Bacteria,2GJPZ@201174|Actinobacteria,4CYV5@85004|Bifidobacteriales 201174|Actinobacteria G ABC transporter permease - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 JIJKFJGP_00252 552531.BIF_01926 4.97e-225 622.0 COG1175@1|root,COG1175@2|Bacteria,2GMTW@201174|Actinobacteria,4CZX2@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 JIJKFJGP_00253 552531.BIF_01925 2.41e-239 658.0 COG1609@1|root,COG1609@2|Bacteria,2GK1X@201174|Actinobacteria,4CZWK@85004|Bifidobacteriales 201174|Actinobacteria K Periplasmic binding protein domain - - - - - - - - - - - - LacI,Peripla_BP_3 JIJKFJGP_00257 552531.BIF_01381 5.74e-241 662.0 COG1215@1|root,COG1215@2|Bacteria,2GNPU@201174|Actinobacteria,4CZ7E@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 JIJKFJGP_00258 552531.BIF_01382 0.0 1016.0 COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4CZD1@85004|Bifidobacteriales 201174|Actinobacteria S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport JIJKFJGP_00259 552531.BIF_01383 2.55e-307 838.0 COG1215@1|root,COG1215@2|Bacteria,2HZ9V@201174|Actinobacteria,4CZ5J@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyl transferase family 21 - - - - - - - - - - - - Glyco_tranf_2_3 JIJKFJGP_00260 552531.BIF_01384 1.78e-207 573.0 COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4CZ0Q@85004|Bifidobacteriales 201174|Actinobacteria V ATPases associated with a variety of cellular activities natA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran JIJKFJGP_00261 552531.BIF_01385 0.0 1100.0 2BWH2@1|root,2Z89R@2|Bacteria,2GMNW@201174|Actinobacteria,4CZP3@85004|Bifidobacteriales 201174|Actinobacteria - - - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - JIJKFJGP_00262 552531.BIF_01386 1.65e-289 798.0 COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria,4CYXQ@85004|Bifidobacteriales 201174|Actinobacteria M D-Ala-D-Ala carboxypeptidase 3 (S13) family dacB - 3.4.16.4 ko:K07259 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S13 JIJKFJGP_00263 552531.BIF_00579 5e-274 749.0 COG0037@1|root,COG0037@2|Bacteria,2GJR4@201174|Actinobacteria,4CYSY@85004|Bifidobacteriales 201174|Actinobacteria J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS GO:0008150,GO:0040007 2.4.2.8,6.3.4.19 ko:K00760,ko:K04075 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 - - - ATP_bind_3,TilS JIJKFJGP_00264 552531.BIF_00577 2.77e-128 365.0 COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4CZNJ@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran JIJKFJGP_00265 552531.BIF_01924 0.0 1354.0 COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4CZ6U@85004|Bifidobacteriales 201174|Actinobacteria O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0030163,GO:0040007,GO:0042623,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 JIJKFJGP_00266 552531.BIF_00485 3.66e-186 520.0 COG0801@1|root,COG0801@2|Bacteria,2H3G6@201174|Actinobacteria,4D0EJ@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folK - 2.7.6.3,4.1.2.25 ko:K13940 ko00790,ko01100,map00790,map01100 M00126 R03503,R03504 RC00002,RC00017,RC00721,RC00943 ko00000,ko00001,ko00002,ko01000 - - - FolB,HPPK JIJKFJGP_00267 552531.BIF_00486 7.39e-148 416.0 2DRQG@1|root,33CMQ@2|Bacteria,2HZP6@201174|Actinobacteria,4D14M@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3180) - - - - - - - - - - - - DUF3180 JIJKFJGP_00268 552531.BIF_00412 4.03e-221 609.0 COG1946@1|root,COG1946@2|Bacteria,2GJ1B@201174|Actinobacteria,4CZRC@85004|Bifidobacteriales 201174|Actinobacteria I Thioesterase-like superfamily tesB - - ko:K10805 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - 4HBT_3 JIJKFJGP_00269 552531.BIF_00411 0.0 1052.0 COG0488@1|root,COG0488@2|Bacteria,2GKBQ@201174|Actinobacteria,4CYWH@85004|Bifidobacteriales 201174|Actinobacteria S ATP-binding cassette protein, ChvD family yjjK GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - - - - - - - - - - ABC_tran,ABC_tran_Xtn JIJKFJGP_00270 552531.BIF_01214 4.14e-91 269.0 COG0242@1|root,COG0242@2|Bacteria,2IJQ5@201174|Actinobacteria,4D14S@85004|Bifidobacteriales 201174|Actinobacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins fms - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase JIJKFJGP_00271 552531.BIF_01213 0.0 885.0 COG2873@1|root,COG2873@2|Bacteria,2I2EB@201174|Actinobacteria,4CYSA@85004|Bifidobacteriales 201174|Actinobacteria H Psort location Cytoplasmic, score 9.98 - - 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 - R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP JIJKFJGP_00272 552531.BIF_01212 6.02e-145 409.0 COG4721@1|root,COG4721@2|Bacteria,2H5VZ@201174|Actinobacteria,4CZ6M@85004|Bifidobacteriales 201174|Actinobacteria S ABC-type cobalt transport system, permease component - - - ko:K16925 - M00582 - - ko00000,ko00002,ko02000 3.A.1.30 - - ABC_cobalt JIJKFJGP_00273 552531.BIF_01211 9.17e-202 562.0 2AUE2@1|root,31K22@2|Bacteria,2IK5N@201174|Actinobacteria,4D0XQ@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00275 552531.BIF_01210 4.11e-223 614.0 2B5NH@1|root,31YHV@2|Bacteria,2HZZE@201174|Actinobacteria,4D2DG@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00276 552531.BIF_00801 0.0 2372.0 COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4CZKT@85004|Bifidobacteriales 201174|Actinobacteria L DNA polymerase III alpha subunit dnaE GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon JIJKFJGP_00278 552531.BIF_00334 5.2e-225 620.0 COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,4CYYR@85004|Bifidobacteriales 201174|Actinobacteria J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 JIJKFJGP_00279 552531.BIF_00335 1.34e-127 362.0 COG0597@1|root,COG0597@2|Bacteria,2GKRX@201174|Actinobacteria,4D0WR@85004|Bifidobacteriales 201174|Actinobacteria MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 JIJKFJGP_00280 552531.BIF_00306 7.28e-149 442.0 COG1566@1|root,COG1566@2|Bacteria,2I2G9@201174|Actinobacteria,4CZ5W@85004|Bifidobacteriales 201174|Actinobacteria V DivIVA protein - - - - - - - - - - - - DivIVA JIJKFJGP_00281 552531.BIF_00305 1.18e-56 176.0 COG0762@1|root,COG0762@2|Bacteria,2GQI1@201174|Actinobacteria,4D17B@85004|Bifidobacteriales 201174|Actinobacteria S YGGT family - - - ko:K02221 - - - - ko00000,ko02044 - - - YGGT JIJKFJGP_00282 552531.BIF_00304 2.22e-103 299.0 COG1799@1|root,COG1799@2|Bacteria,2GNVH@201174|Actinobacteria,4D0RJ@85004|Bifidobacteriales 201174|Actinobacteria D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA sepF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K09772 - - - - ko00000,ko03036 - - - SepF JIJKFJGP_00283 552531.BIF_00177 7.23e-283 775.0 COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,4CZ10@85004|Bifidobacteriales 201174|Actinobacteria D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin JIJKFJGP_00284 552531.BIF_02173 3.31e-316 863.0 COG0042@1|root,COG0042@2|Bacteria,2GJ8I@201174|Actinobacteria,4CZFD@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dus GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090 - - - - - - - - - - Dus JIJKFJGP_00285 552531.BIF_01125 0.0 1019.0 COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4CYZU@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the attachment of glycine to tRNA(Gly) glyQS GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - HGTP_anticodon,tRNA-synt_2b JIJKFJGP_00286 78345.BMERY_0039 7.5e-125 365.0 COG2145@1|root,COG2145@2|Bacteria,2IC73@201174|Actinobacteria,4CZU8@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) thiM - 2.7.1.50 ko:K00878 ko00730,ko01100,map00730,map01100 M00127 R04448 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HK JIJKFJGP_00287 552531.BIF_02010 0.0 1012.0 COG0351@1|root,COG0352@1|root,COG0351@2|Bacteria,COG0352@2|Bacteria,2I2GC@201174|Actinobacteria,4D2V2@85004|Bifidobacteriales 201174|Actinobacteria H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE - 2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17 ko:K03147,ko:K14153 ko00730,ko01100,map00730,map01100 M00127 R03223,R03471,R03472,R04509,R10712 RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin,TMP-TENI JIJKFJGP_00288 552531.BIF_01863 7.04e-79 235.0 COG0011@1|root,COG0011@2|Bacteria,2IQ7E@201174|Actinobacteria,4D14E@85004|Bifidobacteriales 201174|Actinobacteria S Thiamine-binding protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Thiamine_BP JIJKFJGP_00289 552531.BIF_00490 3.28e-257 704.0 COG1609@1|root,COG1609@2|Bacteria,2GJY9@201174|Actinobacteria,4CYU5@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 JIJKFJGP_00290 552531.BIF_00489 9.04e-316 861.0 COG2807@1|root,COG2807@2|Bacteria,2GJRD@201174|Actinobacteria,4CYTK@85004|Bifidobacteriales 201174|Actinobacteria P LacY proton/sugar symporter lacY - - ko:K02532 - - - - ko00000,ko02000 2.A.1.5 - - LacY_symp JIJKFJGP_00291 552531.BIF_01865 0.0 1132.0 COG1621@1|root,COG1621@2|Bacteria,2GJ9T@201174|Actinobacteria,4CZ8W@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 32 family fosC - 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_32C,Glyco_hydro_32N JIJKFJGP_00292 552531.BIF_02174 7.44e-190 527.0 COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria,4CZ9Q@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 JIJKFJGP_00293 552531.BIF_00743 3.8e-264 723.0 COG0715@1|root,COG0715@2|Bacteria,2HZ9T@201174|Actinobacteria,4CZ56@85004|Bifidobacteriales 201174|Actinobacteria P NMT1/THI5 like - - - - - - - - - - - - NMT1 JIJKFJGP_00294 552531.BIF_00171 4.16e-299 815.0 COG1957@1|root,COG1957@2|Bacteria,2I9SG@201174|Actinobacteria,4CZWE@85004|Bifidobacteriales 201174|Actinobacteria F nucleoside hydrolase - - - - - - - - - - - - IU_nuc_hydro JIJKFJGP_00296 552531.BIF_00373 5.72e-195 540.0 COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4CZAR@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.86,2.5.1.88 ko:K00806,ko:K14215,ko:K21273 ko00900,ko01110,map00900,map01110 - R06447,R09244,R09731 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf JIJKFJGP_00297 552531.BIF_00372 3.68e-170 475.0 COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4CZCN@85004|Bifidobacteriales 201174|Actinobacteria L Involved in DNA repair and RecF pathway recombination recO GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N JIJKFJGP_00298 552531.BIF_00144 0.0 1134.0 COG0657@1|root,COG0657@2|Bacteria,2I2GD@201174|Actinobacteria,4CZUD@85004|Bifidobacteriales 201174|Actinobacteria I acetylesterase activity - - - - - - - - - - - - - JIJKFJGP_00299 552531.BIF_00608 1.48e-291 795.0 COG0821@1|root,COG0821@2|Bacteria,2GK2S@201174|Actinobacteria,4CYQB@85004|Bifidobacteriales 201174|Actinobacteria I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE JIJKFJGP_00300 552531.BIF_00605 5.92e-280 766.0 COG0743@1|root,COG0743@2|Bacteria,2GIRV@201174|Actinobacteria,4CZVC@85004|Bifidobacteriales 201174|Actinobacteria I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv2870c DXPR_C,DXP_redisom_C,DXP_reductoisom JIJKFJGP_00301 552531.BIF_00606 0.0 1001.0 COG3170@1|root,COG3170@2|Bacteria,2I2GE@201174|Actinobacteria,4CZDF@85004|Bifidobacteriales 201174|Actinobacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - JIJKFJGP_00303 552531.BIF_01257 1.94e-105 305.0 2B2PP@1|root,31V9E@2|Bacteria,2GV7X@201174|Actinobacteria,4D1H7@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00304 552531.BIF_01256 2.42e-96 280.0 2B57P@1|root,32TPU@2|Bacteria,2I89I@201174|Actinobacteria,4D0P0@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3052) - - - - - - - - - - - - DUF3052 JIJKFJGP_00305 552531.BIF_01255 9.43e-233 640.0 COG3480@1|root,COG3480@2|Bacteria,2GMFX@201174|Actinobacteria,4CYUP@85004|Bifidobacteriales 201174|Actinobacteria T Belongs to the peptidase S16 family sdrC - - ko:K07177 ko02024,map02024 - - - ko00000,ko00001,ko01002 - - - Lon_C JIJKFJGP_00306 552531.BIF_01254 0.0 949.0 COG5282@1|root,COG5282@2|Bacteria,2GJ9K@201174|Actinobacteria,4CYU7@85004|Bifidobacteriales 201174|Actinobacteria S Zincin-like metallopeptidase - - - - - - - - - - - - Zincin_2 JIJKFJGP_00307 552531.BIF_02176 0.0 1039.0 COG0210@1|root,COG0210@2|Bacteria,2GKRW@201174|Actinobacteria,4CZ3A@85004|Bifidobacteriales 201174|Actinobacteria L DNA helicase uvrD2 GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - HRDC,UvrD-helicase,UvrD_C JIJKFJGP_00308 552531.BIF_00526 0.0 939.0 COG3173@1|root,COG3173@2|Bacteria,2I8R6@201174|Actinobacteria,4CYPR@85004|Bifidobacteriales 201174|Actinobacteria S Aminoglycoside phosphotransferase mphA - - - - - - - - - - - APH JIJKFJGP_00309 762211.BSTEL_1511 1.45e-27 101.0 2AS45@1|root,31HGW@2|Bacteria,2HZSD@201174|Actinobacteria,4D1H9@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3107) - - - - - - - - - - - - DUF3107 JIJKFJGP_00310 552531.BIF_00858 1.14e-213 590.0 COG0613@1|root,COG0613@2|Bacteria,2GNAP@201174|Actinobacteria,4CYQ5@85004|Bifidobacteriales 201174|Actinobacteria S DNA polymerase alpha chain like domain PPA1328 - 3.1.3.97,3.1.4.57 ko:K07053,ko:K20859 ko00440,map00440 - R00188,R10972,R10973,R11188 RC00078,RC00296 ko00000,ko00001,ko01000 - - - PHP JIJKFJGP_00311 552531.BIF_00859 3.37e-156 439.0 COG4243@1|root,COG4243@2|Bacteria,2GMVK@201174|Actinobacteria,4CZN1@85004|Bifidobacteriales 201174|Actinobacteria S Vitamin K epoxide reductase - - - - - - - - - - - - VKOR JIJKFJGP_00312 552531.BIF_00860 7.78e-223 615.0 COG0253@1|root,COG0253@2|Bacteria,2GKUD@201174|Actinobacteria,4CYQP@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase JIJKFJGP_00313 552531.BIF_00547 3.84e-186 517.0 COG0796@1|root,COG0796@2|Bacteria,2GN4I@201174|Actinobacteria,4CZ54@85004|Bifidobacteriales 201174|Actinobacteria M Provides the (R)-glutamate required for cell wall biosynthesis murI GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - - Asp_Glu_race JIJKFJGP_00314 552531.BIF_00548 1.21e-207 573.0 COG4667@1|root,COG4667@2|Bacteria,2I8R7@201174|Actinobacteria,4CZUH@85004|Bifidobacteriales 201174|Actinobacteria S Patatin-like phospholipase - - - - - - - - - - - - Patatin JIJKFJGP_00315 552531.BIF_00217 7.34e-197 548.0 COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria,4CYTU@85004|Bifidobacteriales 201174|Actinobacteria O prohibitin homologues hflK GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - - - - - - - - - - Band_7 JIJKFJGP_00316 552531.BIF_00455 9.92e-211 583.0 COG0834@1|root,COG0834@2|Bacteria,2GJH8@201174|Actinobacteria,4CZAC@85004|Bifidobacteriales 201174|Actinobacteria ET Bacterial periplasmic substrate-binding proteins glnH - - ko:K02030,ko:K10039 ko02010,map02010 M00228,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 JIJKFJGP_00317 552531.BIF_00619 2.41e-204 566.0 COG1126@1|root,COG1126@2|Bacteria,2H1ZM@201174|Actinobacteria,4CZTK@85004|Bifidobacteriales 201174|Actinobacteria E ATP binding protein of ABC transporter for glutamate aspartate K02028 glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran JIJKFJGP_00318 552531.BIF_00617 3.77e-157 441.0 COG0765@1|root,COG0765@2|Bacteria,2GN44@201174|Actinobacteria,4CZG7@85004|Bifidobacteriales 201174|Actinobacteria E Binding-protein-dependent transport system inner membrane component glnP - - ko:K02029,ko:K10040 ko02010,map02010 M00228,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 JIJKFJGP_00319 552531.BIF_00616 1.29e-145 412.0 COG0765@1|root,COG0765@2|Bacteria,2GM0I@201174|Actinobacteria,4CZ8E@85004|Bifidobacteriales 201174|Actinobacteria E Binding-protein-dependent transport system inner membrane component glnP2 - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 JIJKFJGP_00320 552531.BIF_00727 2.49e-295 807.0 COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4CZCF@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase class I and II - - 2.6.1.1,2.6.1.2,2.6.1.66,2.6.1.83 ko:K00812,ko:K08969,ko:K10206,ko:K10907,ko:K14260,ko:K14261 ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00034,M00527 R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052,R07396,R07613 RC00006,RC00008,RC00036,RC01847 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 JIJKFJGP_00321 552531.BIF_00728 3.64e-142 402.0 COG2011@1|root,COG2011@2|Bacteria,2GY65@201174|Actinobacteria,4CZP5@85004|Bifidobacteriales 201174|Actinobacteria P Psort location CytoplasmicMembrane, score 9.99 - - - ko:K02072 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - BPD_transp_1 JIJKFJGP_00322 552531.BIF_01221 3e-280 767.0 COG1135@1|root,COG1135@2|Bacteria,2GJ9P@201174|Actinobacteria,4CZYI@85004|Bifidobacteriales 201174|Actinobacteria P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN - - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - ABC_tran,NIL JIJKFJGP_00323 552531.BIF_01222 8.77e-208 576.0 COG1464@1|root,COG1464@2|Bacteria,2GMNI@201174|Actinobacteria,4CZAI@85004|Bifidobacteriales 201174|Actinobacteria M NLPA lipoprotein metQ - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 JIJKFJGP_00324 552531.BIF_01223 1.42e-244 671.0 COG1893@1|root,COG1893@2|Bacteria,2HZCX@201174|Actinobacteria,4CZN4@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C JIJKFJGP_00325 552531.BIF_01224 1.07e-165 462.0 COG0454@1|root,COG0456@2|Bacteria,2IB9K@201174|Actinobacteria,4D0M3@85004|Bifidobacteriales 201174|Actinobacteria K acetyltransferase - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_9 JIJKFJGP_00326 552531.BIF_02011 5.15e-134 379.0 COG2176@1|root,COG2176@2|Bacteria,2I2FU@201174|Actinobacteria,4D10C@85004|Bifidobacteriales 201174|Actinobacteria L Exonuclease, DNA polymerase III, epsilon subunit family - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - BRCT,RNase_T JIJKFJGP_00327 552531.BIF_01209 4.13e-122 348.0 COG1847@1|root,COG1847@2|Bacteria,2GPZK@201174|Actinobacteria,4CYQQ@85004|Bifidobacteriales 201174|Actinobacteria S Putative single-stranded nucleic acids-binding domain jag - - ko:K06346 - - - - ko00000 - - - KH_4,R3H JIJKFJGP_00328 552531.BIF_01208 8.06e-234 644.0 COG0706@1|root,COG0706@2|Bacteria,2GJBU@201174|Actinobacteria,4CYZ2@85004|Bifidobacteriales 201174|Actinobacteria U Membrane protein insertase, YidC Oxa1 family yidC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP JIJKFJGP_00329 552531.BIF_01906 9.33e-20 79.7 COG0230@1|root,COG0230@2|Bacteria,2GQFY@201174|Actinobacteria,4D1EF@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the bacterial ribosomal protein bL34 family rpmH - - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 JIJKFJGP_00330 552531.BIF_00360 0.0 1145.0 COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,4CZDW@85004|Bifidobacteriales 201174|Actinobacteria L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C JIJKFJGP_00331 552531.BIF_01452 7.9e-263 721.0 COG0592@1|root,COG0592@2|Bacteria,2GJK3@201174|Actinobacteria,4CZTV@85004|Bifidobacteriales 201174|Actinobacteria L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 JIJKFJGP_00332 552531.BIF_01454 0.0 922.0 COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria,4CZQT@85004|Bifidobacteriales 201174|Actinobacteria L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N JIJKFJGP_00333 552531.BIF_01455 2.35e-117 335.0 COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,4D157@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF721) - - - - - - - - - - - - DUF721 JIJKFJGP_00334 552531.BIF_01456 0.0 1397.0 COG0187@1|root,COG0187@2|Bacteria,2GKGP@201174|Actinobacteria,4CZ47@85004|Bifidobacteriales 201174|Actinobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim JIJKFJGP_00335 552531.BIF_01457 0.0 1801.0 COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,4CYRP@85004|Bifidobacteriales 201174|Actinobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0008094,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034335,GO:0042623,GO:0061505,GO:0140097 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV JIJKFJGP_00336 552531.BIF_00814 2.65e-108 313.0 COG3266@1|root,COG3266@2|Bacteria,2GKZP@201174|Actinobacteria,4D0XB@85004|Bifidobacteriales 201174|Actinobacteria S Transmembrane domain of unknown function (DUF3566) - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - DUF3566 JIJKFJGP_00337 552531.BIF_00108 3.27e-279 762.0 COG4767@1|root,COG4767@2|Bacteria,2H595@201174|Actinobacteria,4CZBZ@85004|Bifidobacteriales 201174|Actinobacteria V VanZ like family - - - - - - - - - - - - RDD,VanZ JIJKFJGP_00338 552531.BIF_00841 3.88e-207 573.0 COG1272@1|root,COG1272@2|Bacteria,2HRAC@201174|Actinobacteria,4D0D6@85004|Bifidobacteriales 201174|Actinobacteria S Haemolysin-III related - - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII JIJKFJGP_00339 552531.BIF_01557 0.0 901.0 COG0334@1|root,COG0334@2|Bacteria,2GKXG@201174|Actinobacteria,4CYTN@85004|Bifidobacteriales 201174|Actinobacteria E Belongs to the Glu Leu Phe Val dehydrogenases family gdhA GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 - R00248 RC00006,RC02799 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N JIJKFJGP_00340 552531.BIF_01556 4.42e-307 838.0 COG0477@1|root,COG2814@2|Bacteria,2I8HS@201174|Actinobacteria,4CZ4M@85004|Bifidobacteriales 201174|Actinobacteria EGP Transporter major facilitator family protein - - - - - - - - - - - - MFS_1 JIJKFJGP_00341 552531.BIF_02200 6.85e-218 609.0 COG4124@1|root,COG4124@2|Bacteria,2GJ4D@201174|Actinobacteria,4CZ39@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 26 - - 3.2.1.78 ko:K01218 ko00051,ko02024,map00051,map02024 - R01332 RC00467 ko00000,ko00001,ko01000 - GH26 - CBM_11,Glyco_hydro_26,SLH JIJKFJGP_00342 552531.BIF_01553 1.39e-95 280.0 COG1970@1|root,COG1970@2|Bacteria,2IQDN@201174|Actinobacteria,4D13A@85004|Bifidobacteriales 201174|Actinobacteria M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL - - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL JIJKFJGP_00343 552531.BIF_01552 3.45e-68 206.0 COG2308@1|root,COG2308@2|Bacteria,2GN0J@201174|Actinobacteria,4D061@85004|Bifidobacteriales 201174|Actinobacteria S A circularly permuted ATPgrasp gcs2 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K06048 - - - - ko00000,ko01000 - - - Alpha-E,CP_ATPgrasp_1,CP_ATPgrasp_2,GCS2 JIJKFJGP_00346 552531.BIF_01551 4.87e-187 519.0 COG1451@1|root,COG1451@2|Bacteria,2GMP6@201174|Actinobacteria,4CZF9@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function DUF45 - - - ko:K07043 - - - - ko00000 - - - DUF45 JIJKFJGP_00347 552531.BIF_01688 2.87e-101 293.0 29SSD@1|root,30DYB@2|Bacteria,2IJ1J@201174|Actinobacteria,4D0SG@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00348 552531.BIF_01689 6.65e-198 548.0 COG2865@1|root,COG2865@2|Bacteria,2GZ30@201174|Actinobacteria,4CYSX@85004|Bifidobacteriales 201174|Actinobacteria K Putative ATP-dependent DNA helicase recG C-terminal - - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AlbA_2,HATPase_c_4,HTH_24 JIJKFJGP_00349 552531.BIF_01691 0.0 1664.0 COG0178@1|root,COG0178@2|Bacteria,2GNMW@201174|Actinobacteria,4CZ5X@85004|Bifidobacteriales 201174|Actinobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate uvrA3 - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran JIJKFJGP_00350 552531.BIF_01692 2.44e-191 531.0 COG0500@1|root,COG2226@2|Bacteria,2I2I5@201174|Actinobacteria,4D0CB@85004|Bifidobacteriales 201174|Actinobacteria Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11 JIJKFJGP_00351 552531.BIF_01693 1.79e-214 592.0 2A13T@1|root,30P9P@2|Bacteria,2IKBW@201174|Actinobacteria,4D0W0@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00352 552531.BIF_01694 5.12e-139 393.0 COG0431@1|root,COG0431@2|Bacteria,2GMA7@201174|Actinobacteria,4D163@85004|Bifidobacteriales 201174|Actinobacteria S NADPH-dependent FMN reductase - - - ko:K19784 - - - - ko00000 - - - FMN_red JIJKFJGP_00353 552531.BIF_01695 5.46e-136 387.0 2BH0G@1|root,32B0K@2|Bacteria,2GXWI@201174|Actinobacteria,4D1T1@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00354 35760.BCHO_0080 3.27e-25 95.5 2A2ND@1|root,30R0V@2|Bacteria,2HCWR@201174|Actinobacteria,4D2IN@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00357 552531.BIF_01697 2.13e-75 226.0 COG1694@1|root,COG1694@2|Bacteria,2IKRC@201174|Actinobacteria,4D155@85004|Bifidobacteriales 201174|Actinobacteria S MazG-like family - - - - - - - - - - - - MazG-like JIJKFJGP_00358 35760.BCHO_0084 1.15e-31 124.0 COG3410@1|root,COG3410@2|Bacteria,2HNSJ@201174|Actinobacteria,4CZG3@85004|Bifidobacteriales 201174|Actinobacteria L Uncharacterized conserved protein (DUF2075) - - - ko:K09384 - - - - ko00000 - - - DUF2075 JIJKFJGP_00360 552531.BIF_01698 2.53e-243 674.0 COG0270@1|root,COG0270@2|Bacteria,2GJR6@201174|Actinobacteria,4D0YP@85004|Bifidobacteriales 201174|Actinobacteria H C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase,HTH_17,MerR,MerR_1 JIJKFJGP_00361 1384484.AEQU_2083 2.61e-60 198.0 2B1QS@1|root,31U6F@2|Bacteria,2H4U2@201174|Actinobacteria,4CWYD@84998|Coriobacteriia 84998|Coriobacteriia S Type II restriction endonuclease EcoO109I - - - - - - - - - - - - RE_EcoO109I JIJKFJGP_00362 552531.BIF_01700 0.0 1513.0 28IDW@1|root,2Z8G1@2|Bacteria,2I8P7@201174|Actinobacteria,4D07A@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00363 552531.BIF_02041 1.94e-143 404.0 2BG4H@1|root,32A18@2|Bacteria,2GPGE@201174|Actinobacteria,4D1DP@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00364 552531.BIF_01658 0.0 1384.0 2A3T5@1|root,30SB1@2|Bacteria,2IDQE@201174|Actinobacteria,4D0HU@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00365 552531.BIF_01659 0.0 989.0 2C0JV@1|root,30272@2|Bacteria,2IEHU@201174|Actinobacteria,4D0MB@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00366 552531.BIF_01661 1.06e-52 165.0 COG3041@1|root,COG3041@2|Bacteria,2GSX9@201174|Actinobacteria,4D1AZ@85004|Bifidobacteriales 201174|Actinobacteria S Bacterial toxin of type II toxin-antitoxin system, YafQ - - - ko:K19157 - - - - ko00000,ko01000,ko02048 - - - YafQ_toxin JIJKFJGP_00367 1437609.BCAL_2006 5.7e-30 108.0 2B9MK@1|root,322ZW@2|Bacteria,2IQWR@201174|Actinobacteria,4D19K@85004|Bifidobacteriales 201174|Actinobacteria K SpoVT / AbrB like domain - - - - - - - - - - - - MazE_antitoxin JIJKFJGP_00368 552531.BIF_02040 1.01e-86 258.0 COG2337@1|root,COG2337@2|Bacteria,2IKDU@201174|Actinobacteria,4D1BY@85004|Bifidobacteriales 201174|Actinobacteria T Toxic component of a toxin-antitoxin (TA) module - - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin JIJKFJGP_00369 552531.BIF_01662 1.46e-210 583.0 COG0583@1|root,COG0583@2|Bacteria,2HZNN@201174|Actinobacteria,4D12F@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate JIJKFJGP_00370 797515.HMPREF9103_01461 1.14e-30 116.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4H9XJ@91061|Bacilli,3FB4Q@33958|Lactobacillaceae 91061|Bacilli S reductase akr5f - 1.1.1.346 ko:K06221 - - R08878 RC00089 ko00000,ko01000 - - - Aldo_ket_red JIJKFJGP_00371 552531.BIF_01663 6.38e-154 432.0 COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,4CZ1F@85004|Bifidobacteriales 201174|Actinobacteria S Aldo/keto reductase family - - 1.1.1.346 ko:K06221 - - R08878 RC00089 ko00000,ko01000 - - - Aldo_ket_red JIJKFJGP_00372 552531.BIF_01664 0.0 1508.0 COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4CZ2P@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 3 N-terminal domain protein bglB - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C JIJKFJGP_00373 552531.BIF_01665 4.75e-110 315.0 COG3231@1|root,COG3231@2|Bacteria,2IE8S@201174|Actinobacteria,4D02V@85004|Bifidobacteriales 201174|Actinobacteria F Phosphotransferase enzyme family - - 2.7.1.95 ko:K00897 - - - - ko00000,ko01000,ko01504 - - - APH JIJKFJGP_00374 31954.BPSP_0850 1.13e-26 105.0 COG3231@1|root,COG3231@2|Bacteria,2IE8S@201174|Actinobacteria,4D02V@85004|Bifidobacteriales 201174|Actinobacteria F Phosphotransferase enzyme family - - 2.7.1.95 ko:K00897 - - - - ko00000,ko01000,ko01504 - - - APH JIJKFJGP_00375 552531.BIF_01667 1.92e-115 330.0 2D9KB@1|root,32TTF@2|Bacteria,2ISEM@201174|Actinobacteria,4D0VB@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4234) - - - - - - - - - - - - DUF4234 JIJKFJGP_00376 552531.BIF_00065 0.0 1103.0 COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4CZ4K@85004|Bifidobacteriales 201174|Actinobacteria JKL helicase superfamily c-terminal domain - - - - - - - - - - - - DEAD,Helicase_C JIJKFJGP_00377 552531.BIF_00176 2.85e-255 702.0 COG2855@1|root,COG2855@2|Bacteria,2GS6E@201174|Actinobacteria,4CZWB@85004|Bifidobacteriales 201174|Actinobacteria S Conserved hypothetical protein 698 - - - - - - - - - - - - Cons_hypoth698 JIJKFJGP_00378 552531.BIF_01727 0.0 903.0 COG2233@1|root,COG2233@2|Bacteria,2GMH6@201174|Actinobacteria,4CZR8@85004|Bifidobacteriales 201174|Actinobacteria F Permease family rutG - - ko:K02824,ko:K03458 - - - - ko00000,ko02000 2.A.40,2.A.40.1.1,2.A.40.1.2 - - Xan_ur_permease JIJKFJGP_00379 552531.BIF_00424 1.66e-273 746.0 COG0657@1|root,COG0657@2|Bacteria,2HGIX@201174|Actinobacteria,4CZUK@85004|Bifidobacteriales 201174|Actinobacteria I Hydrolase, alpha beta domain protein - - - - - - - - - - - - Abhydrolase_3 JIJKFJGP_00380 552531.BIF_00425 9.64e-47 152.0 2B3YJ@1|root,31WNP@2|Bacteria,2GXM9@201174|Actinobacteria,4D1S2@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00381 552531.BIF_01835 1.32e-76 229.0 COG1917@1|root,COG1917@2|Bacteria,2IHSV@201174|Actinobacteria,4D0ZF@85004|Bifidobacteriales 201174|Actinobacteria S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 JIJKFJGP_00382 552531.BIF_00038 2.17e-256 704.0 COG0012@1|root,COG0012@2|Bacteria,2GIXI@201174|Actinobacteria,4CZBU@85004|Bifidobacteriales 201174|Actinobacteria J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF - - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C JIJKFJGP_00383 552531.BIF_00260 4.3e-186 517.0 COG0345@1|root,COG0345@2|Bacteria,2GJ7D@201174|Actinobacteria,4CZIV@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer JIJKFJGP_00384 552531.BIF_00518 0.0 931.0 COG0596@1|root,COG0596@2|Bacteria,2GK03@201174|Actinobacteria,4CZ9T@85004|Bifidobacteriales 201174|Actinobacteria S alpha/beta hydrolase fold pip - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 JIJKFJGP_00385 552531.BIF_00517 0.0 1597.0 COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria,4CZ1M@85004|Bifidobacteriales 201174|Actinobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA_3 JIJKFJGP_00386 552531.BIF_00653 3.72e-154 434.0 COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4CYQW@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg JIJKFJGP_00387 552531.BIF_00322 0.0 1554.0 COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2GJTZ@201174|Actinobacteria,4CZUR@85004|Bifidobacteriales 201174|Actinobacteria MV MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD JIJKFJGP_00388 552531.BIF_00078 2.32e-219 606.0 COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4CZ04@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter, ATP-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran JIJKFJGP_00389 552531.BIF_01879 1.68e-136 391.0 COG0619@1|root,COG0619@2|Bacteria 2|Bacteria P transmembrane transporter activity ecfT GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K02008,ko:K16783,ko:K16785 ko02010,map02010 M00245,M00246,M00581,M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ JIJKFJGP_00390 552531.BIF_00635 0.0 1013.0 COG1123@1|root,COG4172@2|Bacteria,2H2BQ@201174|Actinobacteria,4CZBA@85004|Bifidobacteriales 201174|Actinobacteria P AAA domain, putative AbiEii toxin, Type IV TA system ykoD - - ko:K16784,ko:K16786,ko:K16787 ko02010,map02010 M00581,M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran JIJKFJGP_00392 552531.BIF_00034 0.0 882.0 COG2873@1|root,COG2873@2|Bacteria,2I2EB@201174|Actinobacteria,4CZCT@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase class-V - - 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 - R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP JIJKFJGP_00393 552531.BIF_00789 1.2e-211 585.0 COG2240@1|root,COG2240@2|Bacteria,2HS59@201174|Actinobacteria,4CYQC@85004|Bifidobacteriales 201174|Actinobacteria H Phosphomethylpyrimidine kinase pdxY - 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 - R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 - - - Phos_pyr_kin JIJKFJGP_00394 552531.BIF_00788 1.89e-114 327.0 COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4D191@85004|Bifidobacteriales 201174|Actinobacteria L Belongs to the UPF0102 family yraN - - ko:K07460 - - - - ko00000 - - - UPF0102 JIJKFJGP_00395 552531.BIF_00191 0.0 964.0 COG0606@1|root,COG0606@2|Bacteria,2GJIQ@201174|Actinobacteria,4CYUB@85004|Bifidobacteriales 201174|Actinobacteria O Magnesium chelatase, subunit ChlI C-terminal comM GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C JIJKFJGP_00396 552531.BIF_02083 1.44e-277 758.0 COG0758@1|root,COG0758@2|Bacteria,2GKDA@201174|Actinobacteria,4CYVW@85004|Bifidobacteriales 201174|Actinobacteria LU DNA recombination-mediator protein A dprA - - ko:K04096 - - - - ko00000 - - - DNA_processg_A JIJKFJGP_00397 552531.BIF_01064 0.0 1206.0 COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4CYT5@85004|Bifidobacteriales 201174|Actinobacteria C Succinate dehydrogenase flavoprotein subunit sdhA GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4,1.4.3.16 ko:K00239,ko:K00278 ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00115,M00149,M00173,M00374,M00376 R00357,R00481,R02164 RC00006,RC00045,RC02566 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C JIJKFJGP_00398 552531.BIF_01063 1.36e-234 645.0 COG0479@1|root,COG0479@2|Bacteria,2GP9C@201174|Actinobacteria,4CZWJ@85004|Bifidobacteriales 201174|Actinobacteria C 4Fe-4S dicluster domain sdhB - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_10,Fer4_8 JIJKFJGP_00399 552531.BIF_01062 2.13e-157 441.0 COG4122@1|root,COG4122@2|Bacteria,2HXV7@201174|Actinobacteria,4CZZN@85004|Bifidobacteriales 201174|Actinobacteria S O-methyltransferase safC - - - - - - - - - - - Methyltransf_3 JIJKFJGP_00400 552531.BIF_01061 1.06e-192 534.0 COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,4CZ8R@85004|Bifidobacteriales 201174|Actinobacteria S Belongs to the LOG family fmt2 - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox JIJKFJGP_00401 552531.BIF_01060 0.0 877.0 COG3004@1|root,COG3004@2|Bacteria,2GKIK@201174|Actinobacteria,4CZES@85004|Bifidobacteriales 201174|Actinobacteria P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons nhaA - - ko:K03313 - - - - ko00000,ko02000 2.A.33.1 - - Na_H_antiport_1 JIJKFJGP_00402 552531.BIF_00320 2.54e-311 846.0 COG1168@1|root,COG1168@2|Bacteria,2GJFQ@201174|Actinobacteria,4CZFH@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase, class I II patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 JIJKFJGP_00405 552531.BIF_00321 0.0 866.0 COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,4CYT6@85004|Bifidobacteriales 201174|Actinobacteria O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX JIJKFJGP_00406 552531.BIF_00225 5.41e-160 449.0 COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4CZVF@85004|Bifidobacteriales 201174|Actinobacteria O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease JIJKFJGP_00407 552531.BIF_00224 3.08e-147 414.0 COG0740@1|root,COG0740@2|Bacteria,2GK5C@201174|Actinobacteria,4CYUU@85004|Bifidobacteriales 201174|Actinobacteria O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP1 - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease JIJKFJGP_00408 552531.BIF_01880 0.0 881.0 COG0038@1|root,COG0038@2|Bacteria,2GPPN@201174|Actinobacteria,4CZPX@85004|Bifidobacteriales 201174|Actinobacteria P Voltage gated chloride channel - - - ko:K03281 - - - - ko00000 2.A.49 - - Voltage_CLC JIJKFJGP_00409 552531.BIF_00120 6.03e-306 837.0 COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,4CZ6P@85004|Bifidobacteriales 201174|Actinobacteria D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N JIJKFJGP_00410 552531.BIF_00713 0.0 888.0 COG0349@1|root,COG0349@2|Bacteria,2GKNM@201174|Actinobacteria,4CYUV@85004|Bifidobacteriales 201174|Actinobacteria J 3'-5' exonuclease rnd - 3.1.13.5 ko:K03684 - - - - ko00000,ko01000,ko03016 - - - DNA_pol_A_exo1,HRDC JIJKFJGP_00411 552531.BIF_00712 6.98e-224 616.0 COG1180@1|root,COG1180@2|Bacteria,2GN2B@201174|Actinobacteria,4CZ5Y@85004|Bifidobacteriales 201174|Actinobacteria C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine pflA - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM JIJKFJGP_00412 552531.BIF_00155 0.0 1614.0 COG1882@1|root,COG1882@2|Bacteria,2GTTT@201174|Actinobacteria,4CZ59@85004|Bifidobacteriales 201174|Actinobacteria C Pyruvate formate lyase-like pflB - 2.3.1.54 ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 - R00212,R06987 RC00004,RC01181,RC02742,RC02833 ko00000,ko00001,ko01000 - - - Gly_radical,PFL-like JIJKFJGP_00413 552531.BIF_01804 2.17e-43 140.0 2EHMB@1|root,33BD3@2|Bacteria,2HZRX@201174|Actinobacteria,4D1G1@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00414 552531.BIF_00593 0.0 1129.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2GK2C@201174|Actinobacteria,4CZ14@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.5.1 ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase JIJKFJGP_00415 552531.BIF_00082 1.09e-288 788.0 COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,4CZC6@85004|Bifidobacteriales 201174|Actinobacteria S Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 JIJKFJGP_00416 552531.BIF_00052 3.75e-155 437.0 COG2011@1|root,COG2011@2|Bacteria,2GY65@201174|Actinobacteria,4CZWG@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component metI - - ko:K02072 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - BPD_transp_1 JIJKFJGP_00417 552531.BIF_00083 6.49e-304 829.0 COG1135@1|root,COG1135@2|Bacteria,2GJ9P@201174|Actinobacteria,4CZYI@85004|Bifidobacteriales 201174|Actinobacteria P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN - - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - ABC_tran,NIL JIJKFJGP_00418 552531.BIF_01747 2.68e-232 641.0 COG1464@1|root,COG1464@2|Bacteria,2GMNI@201174|Actinobacteria,4CZNB@85004|Bifidobacteriales 201174|Actinobacteria P NLPA lipoprotein - - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 JIJKFJGP_00419 552531.BIF_01746 4.86e-134 379.0 COG0652@1|root,COG0652@2|Bacteria,2IFUE@201174|Actinobacteria,4CZSU@85004|Bifidobacteriales 201174|Actinobacteria G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030312,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0140096,GO:1901564 5.2.1.8 ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase JIJKFJGP_00420 552531.BIF_01114 3.16e-197 547.0 2A0I6@1|root,30NNB@2|Bacteria,2GJ8M@201174|Actinobacteria,4D0ZN@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00421 552531.BIF_01113 1.67e-191 532.0 COG0745@1|root,COG0745@2|Bacteria,2GJGU@201174|Actinobacteria,4CZB9@85004|Bifidobacteriales 201174|Actinobacteria KT Transcriptional regulatory protein, C terminal glnR - - - - - - - - - - - Trans_reg_C JIJKFJGP_00422 552531.BIF_01112 4.39e-178 497.0 COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria,4CZ31@85004|Bifidobacteriales 201174|Actinobacteria L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD JIJKFJGP_00423 552531.BIF_00853 0.0 1044.0 COG0747@1|root,COG0747@2|Bacteria,2GM5G@201174|Actinobacteria,4CYUZ@85004|Bifidobacteriales 201174|Actinobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 JIJKFJGP_00424 552531.BIF_00854 0.0 1926.0 COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4CYVG@85004|Bifidobacteriales 201174|Actinobacteria J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1 JIJKFJGP_00425 552531.BIF_00197 1e-135 385.0 COG1522@1|root,COG1522@2|Bacteria,2GK3G@201174|Actinobacteria,4D0XT@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix ASNC type lrp_3 - - ko:K03719 - - - - ko00000,ko03000,ko03036 - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type JIJKFJGP_00426 552531.BIF_01818 1.91e-83 247.0 COG1605@1|root,COG1605@2|Bacteria,2IQ46@201174|Actinobacteria,4D12A@85004|Bifidobacteriales 201174|Actinobacteria E Chorismate mutase type II tyrA - 5.4.99.5 ko:K04092 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_2 JIJKFJGP_00427 552531.BIF_00671 0.0 1163.0 COG1511@1|root,COG1511@2|Bacteria,2I9PN@201174|Actinobacteria,4CZC2@85004|Bifidobacteriales 201174|Actinobacteria S domain protein - - - - - - - - - - - - - JIJKFJGP_00428 552531.BIF_00700 0.0 1091.0 COG1158@1|root,COG1158@2|Bacteria,2GIWY@201174|Actinobacteria,4CZ2Z@85004|Bifidobacteriales 201174|Actinobacteria K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind JIJKFJGP_00429 552531.BIF_01226 0.0 1104.0 COG1232@1|root,COG1232@2|Bacteria,2HZ9K@201174|Actinobacteria,4CZ3Z@85004|Bifidobacteriales 201174|Actinobacteria H Flavin containing amine oxidoreductase - - - - - - - - - - - - Amino_oxidase,NAD_binding_8 JIJKFJGP_00430 552531.BIF_01227 1.87e-68 207.0 2AFXT@1|root,3161G@2|Bacteria,2IKPZ@201174|Actinobacteria,4D0UV@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF2469) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - DUF2469 JIJKFJGP_00431 552531.BIF_01228 7.27e-252 691.0 COG1670@1|root,COG1670@2|Bacteria,2I2GV@201174|Actinobacteria,4CYPW@85004|Bifidobacteriales 201174|Actinobacteria J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 JIJKFJGP_00432 552531.BIF_00924 0.0 989.0 COG0064@1|root,COG0064@2|Bacteria,2GJJH@201174|Actinobacteria,4CYUY@85004|Bifidobacteriales 201174|Actinobacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey JIJKFJGP_00433 552531.BIF_00447 0.0 997.0 COG0154@1|root,COG0154@2|Bacteria,2GJK5@201174|Actinobacteria,4CZ1X@85004|Bifidobacteriales 201174|Actinobacteria F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase JIJKFJGP_00434 1690.BPSG_0770 4.42e-34 117.0 COG0721@1|root,COG0721@2|Bacteria,2IQJN@201174|Actinobacteria,4D10U@85004|Bifidobacteriales 201174|Actinobacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln JIJKFJGP_00435 552531.BIF_01014 8.48e-198 551.0 COG1277@1|root,COG1277@2|Bacteria,2I2HX@201174|Actinobacteria,4D0Z9@85004|Bifidobacteriales 201174|Actinobacteria S ABC-type transport system involved in multi-copper enzyme maturation permease component - - - - - - - - - - - - ABC2_membrane_2 JIJKFJGP_00436 552531.BIF_01013 2.77e-176 492.0 COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4D00Y@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran JIJKFJGP_00437 552531.BIF_01012 7.8e-196 542.0 COG0566@1|root,COG0566@2|Bacteria,2GM1A@201174|Actinobacteria,4CZE8@85004|Bifidobacteriales 201174|Actinobacteria J RNA methyltransferase TrmH family trmH - 2.1.1.34 ko:K00556 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase JIJKFJGP_00438 552531.BIF_02157 6.33e-148 417.0 COG0461@1|root,COG0461@2|Bacteria,2HZDS@201174|Actinobacteria,4CZZ6@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE1 - - - - - - - - - - - - JIJKFJGP_00439 552531.BIF_01885 0.0 901.0 COG2217@1|root,COG2217@2|Bacteria,2I8F8@201174|Actinobacteria,4D0F3@85004|Bifidobacteriales 201174|Actinobacteria P E1-E2 ATPase - - - - - - - - - - - - E1-E2_ATPase JIJKFJGP_00440 552531.BIF_01318 0.0 1702.0 COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4CZDY@85004|Bifidobacteriales 201174|Actinobacteria O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695,ko:K03696 ko01100,ko04213,map01100,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N JIJKFJGP_00441 552531.BIF_01319 1.32e-201 558.0 COG0179@1|root,COG0179@2|Bacteria,2GN2G@201174|Actinobacteria,4CZH5@85004|Bifidobacteriales 201174|Actinobacteria Q Fumarylacetoacetate (FAA) hydrolase family - - - - - - - - - - - - DUF2437,FAA_hydrolase JIJKFJGP_00442 552531.BIF_01320 4.56e-109 316.0 2DNNA@1|root,32Y8E@2|Bacteria,2ISEY@201174|Actinobacteria,4D1A0@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00443 552531.BIF_00999 0.0 1055.0 COG4932@1|root,COG4932@2|Bacteria,2IBAM@201174|Actinobacteria,4D0B6@85004|Bifidobacteriales 201174|Actinobacteria M domain protein - - - - - - - - - - - - GramPos_pilinBB,Gram_pos_anchor JIJKFJGP_00444 552531.BIF_00998 0.0 1725.0 COG2304@1|root,COG2304@2|Bacteria,2I2FN@201174|Actinobacteria,4D2UT@85004|Bifidobacteriales 201174|Actinobacteria Q von Willebrand factor (vWF) type A domain - - - - - - - - - - - - Cna_B,FctA,VWA,VWA_2 JIJKFJGP_00445 552531.BIF_01042 5.75e-244 671.0 COG3764@1|root,COG3764@2|Bacteria,2GNWT@201174|Actinobacteria,4CZMM@85004|Bifidobacteriales 201174|Actinobacteria M Sortase family - - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase JIJKFJGP_00446 552531.BIF_00827 3.91e-200 555.0 COG0325@1|root,COG0325@2|Bacteria,2GMRJ@201174|Actinobacteria,4CZUY@85004|Bifidobacteriales 201174|Actinobacteria S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis - - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N JIJKFJGP_00447 552531.BIF_00826 3.88e-251 689.0 COG0008@1|root,COG0008@2|Bacteria,2GKMT@201174|Actinobacteria,4CYRY@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family gluQ - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c JIJKFJGP_00448 552531.BIF_00339 7.1e-236 652.0 COG5479@1|root,COG5479@2|Bacteria,2GMJR@201174|Actinobacteria,4D0RU@85004|Bifidobacteriales 201174|Actinobacteria M Protein of unknown function (DUF3152) - - - - - - - - - - - - DUF3152 JIJKFJGP_00449 35760.BCHO_1588 7.69e-170 474.0 COG0580@1|root,COG0580@2|Bacteria,2GKK3@201174|Actinobacteria,4CZ7F@85004|Bifidobacteriales 201174|Actinobacteria U Belongs to the MIP aquaporin (TC 1.A.8) family glpF - - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - - MIP JIJKFJGP_00453 552531.BIF_00444 6.82e-174 488.0 COG1520@1|root,COG1520@2|Bacteria,2IBDZ@201174|Actinobacteria,4CYUA@85004|Bifidobacteriales 201174|Actinobacteria T Pfam Adenylate and Guanylate cyclase catalytic domain - - - - - - - - - - - - PQQ_2,zinc_ribbon_2 JIJKFJGP_00454 552531.BIF_01051 3.61e-96 280.0 COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,4D0P9@85004|Bifidobacteriales 201174|Actinobacteria J Binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N JIJKFJGP_00455 552531.BIF_01052 1.06e-48 155.0 COG0238@1|root,COG0238@2|Bacteria,2IQ92@201174|Actinobacteria,4D103@85004|Bifidobacteriales 201174|Actinobacteria J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 JIJKFJGP_00456 552531.BIF_01053 1.77e-124 357.0 COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4CZ5V@85004|Bifidobacteriales 201174|Actinobacteria L Single-stranded DNA-binding protein ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB JIJKFJGP_00457 552531.BIF_01054 5.36e-64 195.0 COG0360@1|root,COG0360@2|Bacteria,2IQHD@201174|Actinobacteria,4D10X@85004|Bifidobacteriales 201174|Actinobacteria J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 JIJKFJGP_00458 552531.BIF_01056 8.13e-244 671.0 COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4CZPM@85004|Bifidobacteriales 201174|Actinobacteria F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N JIJKFJGP_00459 552531.BIF_00857 9.03e-223 615.0 COG0524@1|root,COG0524@2|Bacteria,2I04R@201174|Actinobacteria,4CZIB@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway rbsK - 2.7.1.15 ko:K00852 ko00030,map00030 - R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB JIJKFJGP_00460 552531.BIF_00468 0.0 926.0 COG0477@1|root,COG0477@2|Bacteria,2GJV6@201174|Actinobacteria,4CZH3@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily - - - ko:K08168 - M00704 - - ko00000,ko00002,ko01504,ko02000 2.A.1.3.16,2.A.1.3.22,2.A.1.3.6 - - MFS_1 JIJKFJGP_00461 552531.BIF_00679 3.76e-218 603.0 COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,4CZ0Y@85004|Bifidobacteriales 201174|Actinobacteria F Inosine-uridine preferring nucleoside hydrolase iunH2 - 3.2.2.1 ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro JIJKFJGP_00462 552531.BIF_00680 4.45e-253 694.0 COG1609@1|root,COG1609@2|Bacteria,2GNVD@201174|Actinobacteria,4D05Q@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 JIJKFJGP_00463 552531.BIF_01784 5.86e-121 346.0 COG2151@1|root,COG2151@2|Bacteria,2IKUH@201174|Actinobacteria,4CYRH@85004|Bifidobacteriales 201174|Actinobacteria S Iron-sulfur cluster assembly protein - - - - - - - - - - - - FeS_assembly_P JIJKFJGP_00464 552531.BIF_01785 3.17e-135 383.0 COG0822@1|root,COG0822@2|Bacteria,2IHY9@201174|Actinobacteria,4CZU5@85004|Bifidobacteriales 201174|Actinobacteria C SUF system FeS assembly protein, NifU family iscU - - ko:K04488 - - - - ko00000 - - - NifU_N JIJKFJGP_00465 552531.BIF_00622 2.17e-305 832.0 COG0520@1|root,COG0520@2|Bacteria,2GIVK@201174|Actinobacteria,4CZIU@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 JIJKFJGP_00466 552531.BIF_00623 8.04e-184 511.0 COG0396@1|root,COG0396@2|Bacteria,2GKB7@201174|Actinobacteria,4CZU1@85004|Bifidobacteriales 201174|Actinobacteria O FeS assembly ATPase SufC sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran JIJKFJGP_00467 552531.BIF_00695 8.08e-300 817.0 COG0719@1|root,COG0719@2|Bacteria,2GJNV@201174|Actinobacteria,4CZEE@85004|Bifidobacteriales 201174|Actinobacteria O FeS assembly protein SufD sufD GO:0008150,GO:0009605,GO:0009607,GO:0040007,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 - ko:K09015 - - - - ko00000 - - - UPF0051 JIJKFJGP_00468 552531.BIF_00694 0.0 999.0 COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,4CZPQ@85004|Bifidobacteriales 201174|Actinobacteria O FeS assembly protein SufB sufB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - ko:K09014 - - - - ko00000 - - - UPF0051 JIJKFJGP_00469 552531.BIF_00758 0.0 1113.0 COG1376@1|root,COG1376@2|Bacteria,2GQ7D@201174|Actinobacteria,4CZ5A@85004|Bifidobacteriales 201174|Actinobacteria S L,D-transpeptidase catalytic domain - - - - - - - - - - - - PG_binding_4,YkuD JIJKFJGP_00470 552531.BIF_00104 0.0 1129.0 COG0504@1|root,COG0504@2|Bacteria,2GJ13@201174|Actinobacteria,4CYWE@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1699 CTP_synth_N,GATase JIJKFJGP_00471 552531.BIF_00715 3.78e-73 225.0 COG0366@1|root,COG0366@2|Bacteria,2GKK1@201174|Actinobacteria,4D2UY@85004|Bifidobacteriales 201174|Actinobacteria M Aamy_C - - 3.2.1.1,3.2.1.41 ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 - R02108,R02111,R02112,R11262 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,Big_4,CBM_25,CBM_48,DUF5011,PUD JIJKFJGP_00472 552531.BIF_00181 4.16e-236 649.0 COG1523@1|root,COG1523@2|Bacteria,2I2GM@201174|Actinobacteria,4CYSS@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 13 family pulA - 3.2.1.41,3.2.1.68 ko:K01200,ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02111,R09995,R11261 - ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48,CW_binding_1,DUF3372,PUD JIJKFJGP_00473 552531.BIF_02253 2.25e-109 314.0 COG0366@1|root,COG0366@2|Bacteria,2GKK1@201174|Actinobacteria,4D2UY@85004|Bifidobacteriales 201174|Actinobacteria M Aamy_C - - 3.2.1.1,3.2.1.41 ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 - R02108,R02111,R02112,R11262 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,Big_4,CBM_25,CBM_48,DUF5011,PUD JIJKFJGP_00474 552531.BIF_00151 7.78e-125 355.0 COG0366@1|root,COG0366@2|Bacteria,2GKK1@201174|Actinobacteria,4D15T@85004|Bifidobacteriales 201174|Actinobacteria G Alpha amylase, catalytic domain - - 3.2.1.1,3.2.1.41 ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 - R02108,R02111,R02112,R11262 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_25,CBM_48,DUF5011,PUD JIJKFJGP_00477 552531.BIF_00488 6.74e-281 770.0 2AU5I@1|root,32010@2|Bacteria,2H39A@201174|Actinobacteria,4D1UV@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00478 552531.BIF_01841 1.49e-286 783.0 2AU5I@1|root,31JSE@2|Bacteria,2IJSI@201174|Actinobacteria,4D0VN@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00479 552531.BIF_00657 1.78e-105 303.0 290DA@1|root,2ZN2Q@2|Bacteria,2IG4N@201174|Actinobacteria,4D0Q5@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00480 552531.BIF_00640 2.23e-105 304.0 2B4DR@1|root,31X5B@2|Bacteria,2IPCK@201174|Actinobacteria,4D136@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00481 552531.BIF_00639 1.64e-242 666.0 28JU1@1|root,2Z9J4@2|Bacteria,2IC3T@201174|Actinobacteria,4CZR1@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - GIY-YIG JIJKFJGP_00482 1688.BCUN_0353 2.03e-92 271.0 COG0757@1|root,COG0757@2|Bacteria,2IMBY@201174|Actinobacteria,4D0Q6@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes a trans-dehydration via an enolate intermediate aroQ GO:0003674,GO:0003824,GO:0003855,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_II JIJKFJGP_00483 552531.BIF_00638 0.0 1108.0 COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,2GIUZ@201174|Actinobacteria,4CZ2G@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase,SKI JIJKFJGP_00484 552531.BIF_00637 1.45e-280 767.0 COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4CZ43@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv2540c Chorismate_synt JIJKFJGP_00486 552531.BIF_00634 2.13e-264 728.0 COG1559@1|root,COG1559@2|Bacteria,2GKGQ@201174|Actinobacteria,4CZID@85004|Bifidobacteriales 201174|Actinobacteria S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG JIJKFJGP_00487 552531.BIF_02094 3.78e-112 322.0 COG0816@1|root,COG0816@2|Bacteria,2IQB0@201174|Actinobacteria,4D0WQ@85004|Bifidobacteriales 201174|Actinobacteria L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ruvX GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX JIJKFJGP_00488 552531.BIF_00673 0.0 1763.0 COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,4CZQN@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD JIJKFJGP_00489 552531.BIF_00672 6.54e-46 148.0 2B9VR@1|root,3238X@2|Bacteria,2IQYT@201174|Actinobacteria,4D16I@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00490 552531.BIF_00392 1.31e-84 250.0 COG4768@1|root,COG4768@2|Bacteria,2II1J@201174|Actinobacteria,4D0VH@85004|Bifidobacteriales 201174|Actinobacteria S Bacterial protein of unknown function (DUF948) - - - - - - - - - - - - DUF948 JIJKFJGP_00491 552531.BIF_00391 7.34e-165 462.0 COG0406@1|root,COG0406@2|Bacteria,2GK2I@201174|Actinobacteria,4CZH2@85004|Bifidobacteriales 201174|Actinobacteria G Phosphoglycerate mutase family - - 5.4.2.12 ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - His_Phos_1 JIJKFJGP_00492 552531.BIF_02095 2.01e-81 242.0 COG1950@1|root,COG1950@2|Bacteria,2HZND@201174|Actinobacteria,4D117@85004|Bifidobacteriales 201174|Actinobacteria S Mycobacterial 4 TMS phage holin, superfamily IV - - - ko:K08972 - - - - ko00000 - - - Phage_holin_4_2 JIJKFJGP_00493 552531.BIF_02255 3.61e-141 400.0 COG0522@1|root,COG0522@2|Bacteria,2GIRX@201174|Actinobacteria,4CYSP@85004|Bifidobacteriales 201174|Actinobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 JIJKFJGP_00494 552531.BIF_00428 0.0 1652.0 COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,4CYRJ@85004|Bifidobacteriales 201174|Actinobacteria L DNA helicase pcrA GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C JIJKFJGP_00495 762211.BSTEL_0076 8.71e-119 341.0 COG0503@1|root,COG0503@2|Bacteria,2GJ3S@201174|Actinobacteria,4CYSZ@85004|Bifidobacteriales 201174|Actinobacteria F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis xpt - 2.4.2.22 ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01229,R02142 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran JIJKFJGP_00496 552531.BIF_00074 0.0 920.0 COG2233@1|root,COG2233@2|Bacteria,2GMH6@201174|Actinobacteria,4CZ9F@85004|Bifidobacteriales 201174|Actinobacteria F Permease family pbuX - - ko:K03458 - - - - ko00000 2.A.40 - - Xan_ur_permease JIJKFJGP_00497 552531.BIF_00917 1.5e-151 431.0 COG5434@1|root,COG5434@2|Bacteria,2GN7I@201174|Actinobacteria,4CZ0M@85004|Bifidobacteriales 201174|Actinobacteria M Protein of unknown function (DUF3737) - - - - - - - - - - - - DUF3737 JIJKFJGP_00498 35760.BCHO_1234 6.73e-26 105.0 COG1168@1|root,COG1168@2|Bacteria,2GJFQ@201174|Actinobacteria,4CZFH@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase, class I II - - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 JIJKFJGP_00499 552531.BIF_00916 1.51e-226 626.0 COG1168@1|root,COG1168@2|Bacteria,2GJFQ@201174|Actinobacteria,4CZFH@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase, class I II - - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 JIJKFJGP_00500 552531.BIF_00499 5.4e-239 657.0 COG1476@1|root,COG1476@2|Bacteria,2IAI5@201174|Actinobacteria,4D07G@85004|Bifidobacteriales 201174|Actinobacteria K TRANSCRIPTIONal - - - - - - - - - - - - - JIJKFJGP_00501 552531.BIF_00500 0.0 1073.0 COG0366@1|root,COG0366@2|Bacteria,2GJ2H@201174|Actinobacteria,4D0BM@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 70 - - 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase JIJKFJGP_00502 552531.BIF_00954 1.07e-181 504.0 COG2071@1|root,COG2071@2|Bacteria,2GIV6@201174|Actinobacteria,4D043@85004|Bifidobacteriales 201174|Actinobacteria S Peptidase C26 - - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 JIJKFJGP_00503 552531.BIF_00953 1.63e-110 318.0 COG3760@1|root,COG3760@2|Bacteria,2GT4W@201174|Actinobacteria,4D1JZ@85004|Bifidobacteriales 201174|Actinobacteria S Aminoacyl-tRNA editing domain - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit JIJKFJGP_00504 552531.BIF_00952 1.89e-133 379.0 2B2KY@1|root,31V6C@2|Bacteria,2GV2J@201174|Actinobacteria,4D1K9@85004|Bifidobacteriales 201174|Actinobacteria S ABC-2 family transporter protein - - - - - - - - - - - - ABC2_membrane_5 JIJKFJGP_00505 552531.BIF_00566 2.02e-214 591.0 COG1131@1|root,COG1131@2|Bacteria,2GRE8@201174|Actinobacteria,4CZBH@85004|Bifidobacteriales 201174|Actinobacteria V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran JIJKFJGP_00506 552531.BIF_00567 1.42e-86 259.0 COG1725@1|root,COG1725@2|Bacteria,2IT01@201174|Actinobacteria,4D0UK@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix gluconate operon transcriptional repressor - - - ko:K07979 - - - - ko00000,ko03000 - - - GntR JIJKFJGP_00507 552531.BIF_00568 5.23e-244 670.0 COG1476@1|root,COG1476@2|Bacteria,2IBHI@201174|Actinobacteria,4CZ2T@85004|Bifidobacteriales 201174|Actinobacteria K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 JIJKFJGP_00508 31954.BPSP_0601 1.88e-214 595.0 COG1816@1|root,COG1816@2|Bacteria,2GJ6I@201174|Actinobacteria,4D0A6@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism add1 GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.4.4 ko:K01488 ko00230,ko01100,ko05340,map00230,map01100,map05340 - R01560,R02556 RC00477 ko00000,ko00001,ko01000 - - - A_deaminase JIJKFJGP_00509 552531.BIF_01122 3.44e-182 506.0 2B5Q8@1|root,31YJT@2|Bacteria,2H9WN@201174|Actinobacteria,4D2JA@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00510 552531.BIF_01121 1.23e-67 204.0 COG1605@1|root,COG1605@2|Bacteria,2GT4M@201174|Actinobacteria,4D2KP@85004|Bifidobacteriales 201174|Actinobacteria E Chorismate mutase type II - - 4.2.99.21 ko:K04782 ko01053,ko01110,ko01130,map01053,map01110,map01130 - R06602 RC01549,RC02148 ko00000,ko00001,ko01000 - - - CM_2 JIJKFJGP_00511 552531.BIF_01120 6.73e-207 571.0 COG0703@1|root,COG0703@2|Bacteria,2GQF3@201174|Actinobacteria,4D19J@85004|Bifidobacteriales 201174|Actinobacteria E -acetyltransferase - - - - - - - - - - - - - JIJKFJGP_00512 552531.BIF_01119 1.82e-93 272.0 COG0454@1|root,COG0456@2|Bacteria,2IQSU@201174|Actinobacteria,4D1R6@85004|Bifidobacteriales 201174|Actinobacteria K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 JIJKFJGP_00513 552531.BIF_00109 3.03e-140 395.0 COG0563@1|root,COG0563@2|Bacteria,2I8TV@201174|Actinobacteria 201174|Actinobacteria F adenylate kinase activity - - - - - - - - - - - - - JIJKFJGP_00514 552531.BIF_01838 8.85e-85 249.0 COG1373@1|root,COG1373@2|Bacteria,2I96U@201174|Actinobacteria,4CZD7@85004|Bifidobacteriales 201174|Actinobacteria S AAA domain - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 JIJKFJGP_00515 552531.BIF_00230 5.18e-228 628.0 COG3039@1|root,COG3039@2|Bacteria,2IHK2@201174|Actinobacteria 201174|Actinobacteria L Transposase domain (DUF772) - - - ko:K07481 - - - - ko00000 - - - DDE_Tnp_1,DUF772 JIJKFJGP_00516 552531.BIF_01974 4.41e-92 269.0 COG1396@1|root,COG1396@2|Bacteria,2GPYV@201174|Actinobacteria,4D18X@85004|Bifidobacteriales 201174|Actinobacteria K sequence-specific DNA binding - - - - - - - - - - - - - JIJKFJGP_00517 552531.BIF_00705 0.0 1040.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2GM09@201174|Actinobacteria,4CZC3@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase JIJKFJGP_00518 552531.BIF_00105 0.0 1703.0 COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4CZT5@85004|Bifidobacteriales 201174|Actinobacteria G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase xfp - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N JIJKFJGP_00519 552531.BIF_00008 0.0 1092.0 COG0280@1|root,COG0280@2|Bacteria,2GJ5U@201174|Actinobacteria,4CZE6@85004|Bifidobacteriales 201174|Actinobacteria C phosphate acetyltransferase pta GO:0005575,GO:0005576 2.3.1.8 ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000 - - - AAA_26,DRTGG,PTA_PTB JIJKFJGP_00520 552531.BIF_00693 4.94e-297 811.0 COG0282@1|root,COG0282@2|Bacteria,2GJAW@201174|Actinobacteria,4CZ7V@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv0409 Acetate_kinase JIJKFJGP_00521 552531.BIF_00329 0.0 925.0 COG0128@1|root,COG0128@2|Bacteria,2GJKX@201174|Actinobacteria,4CZBG@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase JIJKFJGP_00523 552531.BIF_00574 1.05e-295 807.0 2DSXT@1|root,32UTZ@2|Bacteria,2GKR7@201174|Actinobacteria,4CZBW@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - DUF998 JIJKFJGP_00524 552531.BIF_00611 0.0 1484.0 COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,4CZGR@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 13 family glgX - 3.2.1.68 ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R09995,R11261 - ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 JIJKFJGP_00525 552531.BIF_01788 3.06e-158 443.0 COG0494@1|root,COG0494@2|Bacteria,2IIY0@201174|Actinobacteria,4D0P8@85004|Bifidobacteriales 201174|Actinobacteria L NUDIX domain - - - - - - - - - - - - NUDIX JIJKFJGP_00526 552531.BIF_00613 3.04e-235 645.0 COG0327@1|root,COG0327@2|Bacteria,2GKHZ@201174|Actinobacteria,4CYXC@85004|Bifidobacteriales 201174|Actinobacteria L NIF3 (NGG1p interacting factor 3) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - NIF3 JIJKFJGP_00527 1688.BCUN_0329 0.0 1323.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4CYVK@85004|Bifidobacteriales 201174|Actinobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 JIJKFJGP_00529 552531.BIF_00124 7.75e-158 445.0 COG3707@1|root,COG3707@2|Bacteria,2GK7T@201174|Actinobacteria,4CYS7@85004|Bifidobacteriales 201174|Actinobacteria T Response regulator receiver domain protein pdtaR GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944 - ko:K22010 - M00839 - - ko00000,ko00002,ko02022 - - - ANTAR,Response_reg JIJKFJGP_00530 552531.BIF_00208 6.77e-153 430.0 COG0494@1|root,COG0494@2|Bacteria,2HEH8@201174|Actinobacteria,4CZD0@85004|Bifidobacteriales 201174|Actinobacteria L NUDIX domain aspA - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX JIJKFJGP_00532 552531.BIF_00125 0.0 950.0 COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria,4CZA8@85004|Bifidobacteriales 201174|Actinobacteria G Pyruvate kinase pyk GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C JIJKFJGP_00533 552531.BIF_00300 5.79e-230 634.0 COG0861@1|root,COG0861@2|Bacteria,2GIWU@201174|Actinobacteria,4CYW2@85004|Bifidobacteriales 201174|Actinobacteria P Integral membrane protein, TerC family terC - - ko:K05794 - - - - ko00000 - - - TerC JIJKFJGP_00534 552531.BIF_00301 0.0 1377.0 COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria,4CZR0@85004|Bifidobacteriales 201174|Actinobacteria L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136 - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB JIJKFJGP_00535 552531.BIF_00408 1.4e-152 428.0 COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria,4D0PG@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - CoaE,GrpB JIJKFJGP_00536 1690.BPSG_0796 4.47e-315 863.0 COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4CZ6S@85004|Bifidobacteriales 201174|Actinobacteria J Ribosomal protein S1 rpsA GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 JIJKFJGP_00537 552531.BIF_01088 3.33e-211 583.0 COG0190@1|root,COG0190@2|Bacteria,2GJZS@201174|Actinobacteria,4CZ53@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0040007,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C JIJKFJGP_00538 552531.BIF_01087 1.26e-236 652.0 COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria,4CZ99@85004|Bifidobacteriales 201174|Actinobacteria P Zinc-uptake complex component A periplasmic - - - ko:K02077 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ZnuA JIJKFJGP_00539 552531.BIF_01086 4.24e-217 599.0 COG1121@1|root,COG1121@2|Bacteria,2GP3A@201174|Actinobacteria,4CZEV@85004|Bifidobacteriales 201174|Actinobacteria P ATPases associated with a variety of cellular activities - - - ko:K02074 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ABC_tran JIJKFJGP_00540 552531.BIF_01817 2.27e-185 517.0 COG1108@1|root,COG1108@2|Bacteria,2GJ7H@201174|Actinobacteria,4CYTG@85004|Bifidobacteriales 201174|Actinobacteria U ABC 3 transport family znuB - - ko:K02075 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ABC-3 JIJKFJGP_00541 552531.BIF_01834 7.88e-116 332.0 COG0245@1|root,COG0245@2|Bacteria,2II8H@201174|Actinobacteria,4D0X6@85004|Bifidobacteriales 201174|Actinobacteria H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF - 2.7.7.60,4.6.1.12 ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633,R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - IspD,YgbB JIJKFJGP_00542 552531.BIF_00324 1.02e-132 378.0 COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4CZXD@85004|Bifidobacteriales 201174|Actinobacteria K CarD-like/TRCF domain carD GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K07736 - - - - ko00000,ko03000 - - - CarD_CdnL_TRCF JIJKFJGP_00543 552531.BIF_00132 0.0 1675.0 COG0296@1|root,COG0296@2|Bacteria,2GJ5C@201174|Actinobacteria,4CZMD@85004|Bifidobacteriales 201174|Actinobacteria G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 JIJKFJGP_00544 552531.BIF_00460 3.21e-168 470.0 COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4CZS5@85004|Bifidobacteriales 201174|Actinobacteria T Response regulator receiver domain protein cseB - - - - - - - - - - - Response_reg,Trans_reg_C JIJKFJGP_00545 552531.BIF_00054 8.38e-258 707.0 COG5002@1|root,COG5002@2|Bacteria,2GIX7@201174|Actinobacteria,4CZNA@85004|Bifidobacteriales 201174|Actinobacteria T ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - - - - - - - - - - HAMP,HATPase_c,HisKA JIJKFJGP_00546 552531.BIF_00572 3.71e-187 519.0 COG1040@1|root,COG1040@2|Bacteria,2I9PA@201174|Actinobacteria,4D11A@85004|Bifidobacteriales 201174|Actinobacteria S Phosphoribosyl transferase domain pyrE_1 - - - - - - - - - - - Pribosyltran JIJKFJGP_00547 552531.BIF_00573 1.75e-197 549.0 COG0561@1|root,COG0561@2|Bacteria,2HZD0@201174|Actinobacteria,4CZ4N@85004|Bifidobacteriales 201174|Actinobacteria T Eukaryotic phosphomannomutase - - - - - - - - - - - - Hydrolase_3,PMM JIJKFJGP_00548 552531.BIF_02110 1.6e-72 219.0 COG3824@1|root,COG3824@2|Bacteria,2IS6W@201174|Actinobacteria,4D0YK@85004|Bifidobacteriales 201174|Actinobacteria S Zincin-like metallopeptidase - - - - - - - - - - - - Zincin_1 JIJKFJGP_00549 552531.BIF_00480 0.0 956.0 2DNQG@1|root,32YJZ@2|Bacteria,2I2FY@201174|Actinobacteria,4CZE9@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00550 552531.BIF_00704 0.0 2006.0 COG1216@1|root,COG5617@1|root,COG1216@2|Bacteria,COG5617@2|Bacteria,2I2FX@201174|Actinobacteria,4CYVM@85004|Bifidobacteriales 201174|Actinobacteria S Glycosyl transferase, family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glyco_trans_2_3 JIJKFJGP_00551 552531.BIF_00546 0.0 915.0 COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,4CZ5B@85004|Bifidobacteriales 201174|Actinobacteria K Cell envelope-related transcriptional attenuator domain yvhJ - - - - - - - - - - - LytR_C,LytR_cpsA_psr JIJKFJGP_00552 552531.BIF_00281 8.99e-234 651.0 COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,4CYQY@85004|Bifidobacteriales 201174|Actinobacteria K Cell envelope-related transcriptional attenuator domain lytR2 - - - - - - - - - - - LytR_cpsA_psr JIJKFJGP_00553 552531.BIF_01833 1.17e-313 860.0 COG1674@1|root,COG1674@2|Bacteria,2GJBR@201174|Actinobacteria,4CYU3@85004|Bifidobacteriales 201174|Actinobacteria D FtsK/SpoIIIE family - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE,Yop-YscD_cpl JIJKFJGP_00554 552531.BIF_02258 5.33e-61 187.0 2DMIE@1|root,32RSG@2|Bacteria,2IQCG@201174|Actinobacteria,4D11W@85004|Bifidobacteriales 201174|Actinobacteria K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA whiB GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K18955 - - - - ko00000,ko03000 - - - Whib JIJKFJGP_00555 552531.BIF_00446 7.4e-223 615.0 COG0583@1|root,COG0583@2|Bacteria,2HZCU@201174|Actinobacteria,4CZT8@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate JIJKFJGP_00556 552531.BIF_01001 5.22e-158 442.0 COG1011@1|root,COG1011@2|Bacteria,2I8XE@201174|Actinobacteria,4D00B@85004|Bifidobacteriales 201174|Actinobacteria S Haloacid dehalogenase-like hydrolase - - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 JIJKFJGP_00557 552531.BIF_01000 1.23e-243 669.0 COG2852@1|root,COG2852@2|Bacteria,2GN40@201174|Actinobacteria,4D0JD@85004|Bifidobacteriales 201174|Actinobacteria S Protein conserved in bacteria - - - - - - - - - - - - DUF559 JIJKFJGP_00558 552531.BIF_00897 9.71e-232 639.0 COG1397@1|root,COG1397@2|Bacteria,2HZFJ@201174|Actinobacteria,4D09C@85004|Bifidobacteriales 201174|Actinobacteria O ADP-ribosylglycohydrolase - - - - - - - - - - - - ADP_ribosyl_GH JIJKFJGP_00559 552531.BIF_00896 1.2e-76 229.0 COG1733@1|root,COG1733@2|Bacteria,2IQ8N@201174|Actinobacteria,4D2RH@85004|Bifidobacteriales 201174|Actinobacteria K HxlR-like helix-turn-helix - - - - - - - - - - - - HxlR JIJKFJGP_00560 1410650.JHWL01000028_gene2214 1.25e-66 208.0 COG0494@1|root,COG0494@2|Bacteria,1V55F@1239|Firmicutes,24MBW@186801|Clostridia,4BX0S@830|Butyrivibrio 186801|Clostridia L NUDIX domain - - - - - - - - - - - - NUDIX JIJKFJGP_00561 552531.BIF_00894 6.8e-104 300.0 COG0454@1|root,COG0456@2|Bacteria,2IHRD@201174|Actinobacteria,4D10V@85004|Bifidobacteriales 201174|Actinobacteria K Psort location Cytoplasmic, score 8.87 ypeA - 2.3.1.1 ko:K22477 ko00220,ko01210,ko01230,map00220,map01210,map01230 M00028 R00259 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_1 JIJKFJGP_00562 552531.BIF_00893 5.35e-160 450.0 COG0461@1|root,COG0461@2|Bacteria,2GM5A@201174|Actinobacteria,4CZHB@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran JIJKFJGP_00563 552531.BIF_00173 8.93e-241 662.0 COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4CYU2@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily pyrD - 1.3.1.14 ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01869 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh JIJKFJGP_00564 552531.BIF_02073 3.32e-202 559.0 COG0543@1|root,COG0543@2|Bacteria,2HQ24@201174|Actinobacteria,4CZC1@85004|Bifidobacteriales 201174|Actinobacteria C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B pyrK - - ko:K02823 ko00240,ko01100,map00240,map01100 - - - ko00000,ko00001 - - - DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1 JIJKFJGP_00565 552531.BIF_00848 1.68e-225 621.0 COG0284@1|root,COG0284@2|Bacteria,2GKWK@201174|Actinobacteria,4CZAK@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the OMP decarboxylase family. Type 2 subfamily pyrF - 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase JIJKFJGP_00566 552531.BIF_00849 0.0 970.0 COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,4CZIW@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily pyrC GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 JIJKFJGP_00567 552531.BIF_01872 1.83e-96 280.0 COG1781@1|root,COG1781@2|Bacteria,2IFDF@201174|Actinobacteria,4D0QN@85004|Bifidobacteriales 201174|Actinobacteria F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein pyrI - - ko:K00610 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002 - - - PyrI,PyrI_C JIJKFJGP_00568 552531.BIF_00850 6.91e-242 665.0 COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4CYZR@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the ATCase OTCase family pyrB - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N JIJKFJGP_00569 552531.BIF_01532 1.33e-115 330.0 2DMJC@1|root,32RYJ@2|Bacteria,2IHZV@201174|Actinobacteria,4D0UY@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4186) - - - - - - - - - - - - DUF4186 JIJKFJGP_00570 552531.BIF_00377 0.0 2045.0 COG1391@1|root,COG1391@2|Bacteria,2GJ91@201174|Actinobacteria,4CYQE@85004|Bifidobacteriales 201174|Actinobacteria H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE JIJKFJGP_00571 552531.BIF_00317 6.6e-206 570.0 COG0685@1|root,COG0685@2|Bacteria,2GJTN@201174|Actinobacteria,4CZ22@85004|Bifidobacteriales 201174|Actinobacteria E Methylenetetrahydrofolate reductase metF - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR JIJKFJGP_00572 552531.BIF_00275 0.0 1529.0 COG0620@1|root,COG0620@2|Bacteria,2GIXA@201174|Actinobacteria,4CYWM@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0040007,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_1,Meth_synt_2 JIJKFJGP_00573 552531.BIF_01907 1.07e-127 363.0 COG2062@1|root,COG2062@2|Bacteria,2GJ0I@201174|Actinobacteria,4D05N@85004|Bifidobacteriales 201174|Actinobacteria T Phosphoglycerate mutase family sixA - - ko:K08296 - - - - ko00000,ko01000 - - - His_Phos_1 JIJKFJGP_00574 552531.BIF_00254 7.41e-254 696.0 COG2519@1|root,COG2519@2|Bacteria,2GJPD@201174|Actinobacteria,4CYUG@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA trmI GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 ko:K07442 - - - - ko00000,ko01000,ko03016 - - - GCD14,GCD14_N JIJKFJGP_00575 552531.BIF_00126 1.41e-203 564.0 COG1119@1|root,COG1119@2|Bacteria,2GIXX@201174|Actinobacteria,4CZDS@85004|Bifidobacteriales 201174|Actinobacteria P ATPases associated with a variety of cellular activities ylmA - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran JIJKFJGP_00576 552531.BIF_00645 2.02e-311 848.0 COG0297@1|root,COG0297@2|Bacteria,2I2EE@201174|Actinobacteria,4CZKY@85004|Bifidobacteriales 201174|Actinobacteria G Starch synthase catalytic domain glgA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 ko:K16148 ko00500,ko01100,map00500,map01100 - R02421,R11530 RC00005,RC00049,RC02748 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 JIJKFJGP_00577 552531.BIF_00644 4.8e-114 327.0 COG1225@1|root,COG1225@2|Bacteria,2IHZ6@201174|Actinobacteria,4D0PN@85004|Bifidobacteriales 201174|Actinobacteria O Redoxin bcp - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA JIJKFJGP_00578 552531.BIF_01871 1.11e-103 300.0 2BI32@1|root,32C84@2|Bacteria,2IDD6@201174|Actinobacteria,4D0PC@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - PsbJ JIJKFJGP_00579 552531.BIF_00406 0.0 1047.0 COG0493@1|root,COG0493@2|Bacteria,2GJ0A@201174|Actinobacteria,4CZ7B@85004|Bifidobacteriales 201174|Actinobacteria C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster gltD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - iNJ661.Rv3858c Fer4_20,Pyr_redox_2 JIJKFJGP_00580 552531.BIF_00554 0.0 3050.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2GN09@201174|Actinobacteria,4CZB8@85004|Bifidobacteriales 201174|Actinobacteria E glutamate synthase NADPH large subunit gltB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase JIJKFJGP_00581 552531.BIF_00466 0.0 902.0 COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria,4CZ81@85004|Bifidobacteriales 201174|Actinobacteria H Involved in the biosynthesis of porphyrin-containing compound hemN GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - iNJ661.Rv2388c HemN_C,Radical_SAM JIJKFJGP_00582 552531.BIF_01829 0.0 1237.0 COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria,4CYWI@85004|Bifidobacteriales 201174|Actinobacteria M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C JIJKFJGP_00583 552531.BIF_01828 1.36e-46 150.0 COG0268@1|root,COG0268@2|Bacteria,2IQ73@201174|Actinobacteria,4D18U@85004|Bifidobacteriales 201174|Actinobacteria J Binds directly to 16S ribosomal RNA rpsT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p JIJKFJGP_00584 552531.BIF_01827 1.74e-179 500.0 COG2860@1|root,COG2860@2|Bacteria,2GMI4@201174|Actinobacteria,4CZ51@85004|Bifidobacteriales 201174|Actinobacteria S UPF0126 domain - - - - - - - - - - - - UPF0126 JIJKFJGP_00585 552531.BIF_01826 2.14e-289 788.0 COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,4CZD9@85004|Bifidobacteriales 201174|Actinobacteria E Amino-transferase class IV ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 JIJKFJGP_00586 552531.BIF_00020 6.37e-139 395.0 COG1825@1|root,COG1825@2|Bacteria,2GJPJ@201174|Actinobacteria,4CZ7W@85004|Bifidobacteriales 201174|Actinobacteria J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C JIJKFJGP_00587 552531.BIF_00122 2.54e-249 685.0 COG1073@1|root,COG1073@2|Bacteria,2HZEB@201174|Actinobacteria,4D02D@85004|Bifidobacteriales 201174|Actinobacteria S alpha beta - - - ko:K06889 - - - - ko00000 - - - Abhydrolase_6,Hydrolase_4 JIJKFJGP_00588 552531.BIF_00441 0.0 881.0 COG1282@1|root,COG1282@2|Bacteria,2GNKB@201174|Actinobacteria,4CZF5@85004|Bifidobacteriales 201174|Actinobacteria C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntB - 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB JIJKFJGP_00589 552531.BIF_00112 4.73e-62 191.0 COG3288@1|root,COG3288@2|Bacteria,2IKR9@201174|Actinobacteria,4D12D@85004|Bifidobacteriales 201174|Actinobacteria C 4TM region of pyridine nucleotide transhydrogenase, mitoch pntAB - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB_4TM JIJKFJGP_00590 552531.BIF_00111 2.51e-258 710.0 COG3288@1|root,COG3288@2|Bacteria,2I2FZ@201174|Actinobacteria,4CZZ3@85004|Bifidobacteriales 201174|Actinobacteria C NAD(P) transhydrogenase subunit alpha part 1 K00324 pntA - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM JIJKFJGP_00594 31954.BPSP_1113 2.31e-56 191.0 COG0738@1|root,COG0738@2|Bacteria,2HZX0@201174|Actinobacteria,4D231@85004|Bifidobacteriales 201174|Actinobacteria G Major facilitator superfamily - - - - - - - - - - - - MFS_1 JIJKFJGP_00596 552531.BIF_00970 5.36e-282 773.0 COG0738@1|root,COG0738@2|Bacteria,2HWKN@201174|Actinobacteria,4CYRZ@85004|Bifidobacteriales 201174|Actinobacteria G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 JIJKFJGP_00597 552531.BIF_00971 1.21e-288 788.0 COG0438@1|root,COG0438@2|Bacteria,2GP0E@201174|Actinobacteria,4CZN5@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyl transferase 4-like domain - - 2.4.1.345 ko:K08256 - - R11702 - ko00000,ko01000,ko01003 - GT4 - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 JIJKFJGP_00598 552531.BIF_01033 0.0 1524.0 COG0187@1|root,COG0187@2|Bacteria,2GM1E@201174|Actinobacteria,4CYXR@85004|Bifidobacteriales 201174|Actinobacteria L DNA topoisomerase (ATP-hydrolyzing) gyrB2 - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim JIJKFJGP_00599 552531.BIF_01031 2.66e-264 735.0 COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CZQC@85004|Bifidobacteriales 201174|Actinobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth sigA - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 JIJKFJGP_00600 552531.BIF_01850 8.16e-167 468.0 2B5AP@1|root,31Y4U@2|Bacteria,2IF9M@201174|Actinobacteria,4D15J@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - DUF4192 JIJKFJGP_00601 552531.BIF_01405 7.37e-259 710.0 COG0142@1|root,COG0142@2|Bacteria,2GJEK@201174|Actinobacteria,4CZQV@85004|Bifidobacteriales 201174|Actinobacteria H Belongs to the FPP GGPP synthase family idsA - 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13787 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00365 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt JIJKFJGP_00602 552531.BIF_01407 0.0 1438.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4CYTR@85004|Bifidobacteriales 201174|Actinobacteria KLT PASTA pknL GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase JIJKFJGP_00603 552531.BIF_02264 1.73e-178 497.0 COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,4CZBB@85004|Bifidobacteriales 201174|Actinobacteria I Phosphate acyltransferases plsC2 - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase JIJKFJGP_00604 552531.BIF_02085 7.66e-127 363.0 2AP35@1|root,31E4N@2|Bacteria,2IBUY@201174|Actinobacteria,4D0R7@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00605 552531.BIF_01409 3.49e-247 681.0 COG0547@1|root,COG0547@2|Bacteria,2GM4G@201174|Actinobacteria,4CZKZ@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 JIJKFJGP_00606 552531.BIF_00806 0.0 1909.0 COG0653@1|root,COG0653@2|Bacteria,2GIRT@201174|Actinobacteria,4CYX6@85004|Bifidobacteriales 201174|Actinobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW JIJKFJGP_00607 552531.BIF_00013 1.82e-160 449.0 COG1544@1|root,COG1544@2|Bacteria,2GMYF@201174|Actinobacteria,4CZ3H@85004|Bifidobacteriales 201174|Actinobacteria J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE JIJKFJGP_00609 552531.BIF_00423 2.43e-147 415.0 COG2137@1|root,COG2137@2|Bacteria,2INKM@201174|Actinobacteria,4D0Y4@85004|Bifidobacteriales 201174|Actinobacteria S Modulates RecA activity recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX JIJKFJGP_00610 552531.BIF_00053 6.98e-265 726.0 COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4CYYY@85004|Bifidobacteriales 201174|Actinobacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA JIJKFJGP_00611 552531.BIF_02265 1.78e-58 181.0 2EFU9@1|root,339KE@2|Bacteria,2GQJW@201174|Actinobacteria,4D16T@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3046) - - - - - - - - - - - - DUF3046 JIJKFJGP_00612 552531.BIF_00839 6.75e-113 325.0 COG1426@1|root,COG1426@2|Bacteria,2I2G5@201174|Actinobacteria,4D0PT@85004|Bifidobacteriales 201174|Actinobacteria K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_31 JIJKFJGP_00613 552531.BIF_00840 1.92e-144 410.0 COG1546@1|root,COG1546@2|Bacteria,2IQ8T@201174|Actinobacteria,4D0CM@85004|Bifidobacteriales 201174|Actinobacteria S Belongs to the CinA family cinA - 3.5.1.42 ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA JIJKFJGP_00614 552531.BIF_00018 8.42e-156 437.0 COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,4CZ36@85004|Bifidobacteriales 201174|Actinobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf JIJKFJGP_00615 552531.BIF_00512 0.0 1738.0 COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4CZ5T@85004|Bifidobacteriales 201174|Actinobacteria D FtsK SpoIIIE family protein ftsK GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma JIJKFJGP_00616 552531.BIF_01017 4.34e-247 679.0 COG0324@1|root,COG0324@2|Bacteria,2GKFT@201174|Actinobacteria,4CZNS@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT JIJKFJGP_00617 552531.BIF_01018 0.0 1001.0 COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4CZFB@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 JIJKFJGP_00618 552531.BIF_02086 3.69e-184 512.0 COG2357@1|root,COG2357@2|Bacteria,2GKF8@201174|Actinobacteria,4CYXP@85004|Bifidobacteriales 201174|Actinobacteria S Region found in RelA / SpoT proteins ywaC - 2.7.6.5 ko:K07816 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - RelA_SpoT JIJKFJGP_00620 552531.BIF_02266 6.82e-254 695.0 COG3804@1|root,COG3804@2|Bacteria,2HY5U@201174|Actinobacteria,4D0F7@85004|Bifidobacteriales 201174|Actinobacteria S Dihydrodipicolinate reductase, N-terminus - - 1.4.1.12,1.4.1.26 ko:K21672 ko00310,ko00330,ko00472,map00310,map00330,map00472 - R02825,R04200,R04201,R04687,R04688 RC00249,RC00790 ko00000,ko00001,ko01000 - - - DapB_N JIJKFJGP_00621 552531.BIF_00333 3.98e-295 807.0 COG0842@1|root,COG0842@2|Bacteria,2H9HW@201174|Actinobacteria,4CZ1J@85004|Bifidobacteriales 201174|Actinobacteria V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 JIJKFJGP_00622 552531.BIF_00438 1.71e-301 823.0 COG0842@1|root,COG0842@2|Bacteria,2IBJP@201174|Actinobacteria,4CZD5@85004|Bifidobacteriales 201174|Actinobacteria V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 JIJKFJGP_00623 552531.BIF_00440 1.62e-236 650.0 COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4CYUQ@85004|Bifidobacteriales 201174|Actinobacteria V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 JIJKFJGP_00624 552531.BIF_00046 2.19e-271 743.0 COG4585@1|root,COG4585@2|Bacteria,2I9G4@201174|Actinobacteria,4CZHY@85004|Bifidobacteriales 201174|Actinobacteria T Histidine kinase - - - - - - - - - - - - HisKA_3 JIJKFJGP_00625 552531.BIF_00535 9.39e-149 419.0 COG2197@1|root,COG2197@2|Bacteria,2IBZ9@201174|Actinobacteria,4D07J@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg JIJKFJGP_00626 552531.BIF_00536 5.27e-195 540.0 COG1479@1|root,COG1479@2|Bacteria,2I99F@201174|Actinobacteria,4CZ4G@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function DUF262 - - - - - - - - - - - - DUF1524,DUF262 JIJKFJGP_00627 552531.BIF_01749 1.53e-189 530.0 COG0300@1|root,COG0300@2|Bacteria,2GKJE@201174|Actinobacteria,4CZUC@85004|Bifidobacteriales 201174|Actinobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - ko:K07124 - - - - ko00000 - - - adh_short JIJKFJGP_00628 552531.BIF_01143 0.0 1812.0 COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4CZ24@85004|Bifidobacteriales 201174|Actinobacteria P E1-E2 ATPase - - 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - Cupredoxin_1,E1-E2_ATPase,HMA,Hydrolase,YHS JIJKFJGP_00629 552531.BIF_01144 2.17e-247 679.0 COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,2GJ1S@201174|Actinobacteria,4CZXJ@85004|Bifidobacteriales 201174|Actinobacteria O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008113,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0016491,GO:0016667,GO:0016671,GO:0020012,GO:0030682,GO:0033744,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0075136 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 - - - - ko00000,ko01000 - - - PMSR,SelR JIJKFJGP_00630 552531.BIF_01145 0.0 879.0 COG1114@1|root,COG1114@2|Bacteria,2GNMD@201174|Actinobacteria,4CZIP@85004|Bifidobacteriales 201174|Actinobacteria U Component of the transport system for branched-chain amino acids brnQ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03311 - - - - ko00000 2.A.26 - - Branch_AA_trans JIJKFJGP_00631 764298.STRMA_1005 2.15e-22 98.2 COG3340@1|root,COG3340@2|Bacteria,1V244@1239|Firmicutes,4HN92@91061|Bacilli 91061|Bacilli E Belongs to the peptidase S51 family M1-966 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 ko:K05995 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S51 JIJKFJGP_00632 552531.BIF_01147 0.0 968.0 COG0362@1|root,COG0362@2|Bacteria,2GJ2J@201174|Actinobacteria,4CZFG@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 JIJKFJGP_00633 552531.BIF_00792 9.91e-189 526.0 COG0363@1|root,COG0363@2|Bacteria,2GMQ2@201174|Actinobacteria,4CZRG@85004|Bifidobacteriales 201174|Actinobacteria G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Glucosamine_iso JIJKFJGP_00634 552531.BIF_00791 5.42e-232 638.0 COG3429@1|root,COG3429@2|Bacteria,2GJ1H@201174|Actinobacteria,4CZI4@85004|Bifidobacteriales 201174|Actinobacteria G Glucose-6-phosphate dehydrogenase subunit opcA - - - - - - - - - - - OpcA_G6PD_assem JIJKFJGP_00635 552531.BIF_00790 0.0 1078.0 COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4CYQM@85004|Bifidobacteriales 201174|Actinobacteria G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N JIJKFJGP_00636 552531.BIF_00041 0.0 1330.0 COG0370@1|root,COG0370@2|Bacteria,2GTV2@201174|Actinobacteria,4CZRU@85004|Bifidobacteriales 201174|Actinobacteria P transporter of a GTP-driven Fe(2 ) uptake system feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoA,FeoB_C,FeoB_N,Gate JIJKFJGP_00637 552531.BIF_00255 6.85e-54 169.0 COG1918@1|root,COG1918@2|Bacteria,2GS42@201174|Actinobacteria,4D1FW@85004|Bifidobacteriales 201174|Actinobacteria P FeoA - - - ko:K04758 - - - - ko00000,ko02000 - - - FeoA JIJKFJGP_00638 552531.BIF_00795 0.0 967.0 COG1027@1|root,COG1027@2|Bacteria,2I2HG@201174|Actinobacteria,4CZ6N@85004|Bifidobacteriales 201174|Actinobacteria E Fumarase C C-terminus aspA - 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 - R00490 RC00316,RC02799 ko00000,ko00001,ko01000 - - - FumaraseC_C,Lyase_1 JIJKFJGP_00639 552531.BIF_00796 3.72e-105 304.0 COG3613@1|root,COG3613@2|Bacteria,2IHGG@201174|Actinobacteria,4D0T2@85004|Bifidobacteriales 201174|Actinobacteria F Nucleoside 2-deoxyribosyltransferase - - - - - - - - - - - - Nuc_deoxyrib_tr JIJKFJGP_00640 552531.BIF_00256 1.2e-116 334.0 COG1846@1|root,COG1846@2|Bacteria,2IQ1Z@201174|Actinobacteria,4D13P@85004|Bifidobacteriales 201174|Actinobacteria K Winged helix DNA-binding domain - - - - - - - - - - - - MarR_2 JIJKFJGP_00642 552531.BIF_00534 7.43e-130 368.0 COG3910@1|root,COG3910@2|Bacteria,2GNJ2@201174|Actinobacteria,4D0EW@85004|Bifidobacteriales 201174|Actinobacteria S AAA domain, putative AbiEii toxin, Type IV TA system - - - - - - - - - - - - AAA_21,AAA_23 JIJKFJGP_00643 552531.BIF_00533 8.43e-94 275.0 COG1132@1|root,COG1132@2|Bacteria 2|Bacteria V (ABC) transporter - - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane JIJKFJGP_00644 552531.BIF_01780 2.88e-43 141.0 COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CZWS@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter transmembrane region - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran JIJKFJGP_00645 552531.BIF_00149 0.0 1524.0 COG1966@1|root,COG1966@2|Bacteria,2GIYX@201174|Actinobacteria,4CZWH@85004|Bifidobacteriales 201174|Actinobacteria T 5TM C-terminal transporter carbon starvation CstA cstA - - ko:K06200 - - - - ko00000 - - - CstA,CstA_5TM JIJKFJGP_00646 1690.BPSG_0830 5.3e-22 87.0 COG2879@1|root,COG2879@2|Bacteria,2GQWY@201174|Actinobacteria,4D1IG@85004|Bifidobacteriales 201174|Actinobacteria S Selenoprotein, putative - - - - - - - - - - - - Sel_put JIJKFJGP_00647 552531.BIF_00491 9.99e-300 823.0 COG1472@1|root,COG1472@2|Bacteria,2GM43@201174|Actinobacteria,4CZ6R@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 3 N-terminal domain protein - - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3 JIJKFJGP_00648 552531.BIF_00729 0.0 1847.0 COG1615@1|root,COG1615@2|Bacteria,2GMP3@201174|Actinobacteria,4CYW1@85004|Bifidobacteriales 201174|Actinobacteria S Uncharacterised protein family (UPF0182) - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K09118 - - - - ko00000 - - - UPF0182 JIJKFJGP_00649 552531.BIF_01167 7.24e-142 400.0 COG1247@1|root,COG1247@2|Bacteria,2HZCB@201174|Actinobacteria,4CZQI@85004|Bifidobacteriales 201174|Actinobacteria M Acetyltransferase (GNAT) domain - - 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_1,Acetyltransf_3,Acetyltransf_4 JIJKFJGP_00650 1690.BPSG_0826 3.18e-133 378.0 COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,4CZBE@85004|Bifidobacteriales 201174|Actinobacteria J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro JIJKFJGP_00651 552531.BIF_01169 0.0 2344.0 COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,4CZ8X@85004|Bifidobacteriales 201174|Actinobacteria L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF JIJKFJGP_00653 552531.BIF_00066 3.28e-165 462.0 COG1116@1|root,COG1116@2|Bacteria,2GM4Y@201174|Actinobacteria,4D2SN@85004|Bifidobacteriales 201174|Actinobacteria P ATPases associated with a variety of cellular activities ssuB - - ko:K15555 ko00920,ko02010,map00920,map02010 M00436 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.17.2 - - ABC_tran JIJKFJGP_00654 552531.BIF_02068 1.14e-224 622.0 COG0715@1|root,COG0715@2|Bacteria,2GK7X@201174|Actinobacteria,4CYWY@85004|Bifidobacteriales 201174|Actinobacteria P NMT1-like family - - - ko:K15553 ko00920,ko02010,map00920,map02010 M00436 - - ko00000,ko00001,ko00002,ko02000 3.A.1.17.2 - - NMT1 JIJKFJGP_00655 552531.BIF_00922 3.38e-209 580.0 COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria,4CZAH@85004|Bifidobacteriales 201174|Actinobacteria U Binding-protein-dependent transport system inner membrane component - - - ko:K15554 ko00920,ko02010,map00920,map02010 M00436 - - ko00000,ko00001,ko00002,ko02000 3.A.1.17.2 - - BPD_transp_1 JIJKFJGP_00656 552531.BIF_01197 8.66e-313 852.0 COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria,4CYT3@85004|Bifidobacteriales 201174|Actinobacteria G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N JIJKFJGP_00657 552531.BIF_01196 3.48e-128 365.0 COG2919@1|root,COG2919@2|Bacteria,2IR5G@201174|Actinobacteria,4D0SS@85004|Bifidobacteriales 201174|Actinobacteria D Septum formation initiator - - - - - - - - - - - - DivIC JIJKFJGP_00658 552531.BIF_01825 2.96e-144 406.0 COG1507@1|root,COG1507@2|Bacteria,2I8CS@201174|Actinobacteria,4CZQX@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF501) - - - ko:K09009 - - - - ko00000 - - - DUF501 JIJKFJGP_00659 552531.BIF_01195 2.94e-238 655.0 COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria,4CZCS@85004|Bifidobacteriales 201174|Actinobacteria FP Ppx/GppA phosphatase family ppx - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA JIJKFJGP_00661 552531.BIF_01194 1.24e-136 388.0 2ASIR@1|root,31HZA@2|Bacteria,2IHD9@201174|Actinobacteria,4D0QP@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00662 552531.BIF_01193 0.0 996.0 COG1760@1|root,COG1760@2|Bacteria,2GJPA@201174|Actinobacteria,4CZ6I@85004|Bifidobacteriales 201174|Actinobacteria E Serine dehydratase alpha chain sdaA GO:0003674,GO:0003824,GO:0003941,GO:0016829,GO:0016840,GO:0016841 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha,SDH_beta JIJKFJGP_00663 552531.BIF_01560 0.0 908.0 COG0477@1|root,COG2814@2|Bacteria,2GKMQ@201174|Actinobacteria,4CZ6D@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 JIJKFJGP_00664 552531.BIF_01561 1.51e-159 446.0 COG0406@1|root,COG0406@2|Bacteria,2GMXF@201174|Actinobacteria,4CZ0Z@85004|Bifidobacteriales 201174|Actinobacteria G Phosphoglycerate mutase family - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - - - - - - - - - - His_Phos_1 JIJKFJGP_00665 552531.BIF_01562 2.38e-224 618.0 2BR5C@1|root,32K3E@2|Bacteria,2I8T9@201174|Actinobacteria,4CZ8U@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00666 552531.BIF_01563 1.74e-130 370.0 COG2246@1|root,COG2246@2|Bacteria,2HZBR@201174|Actinobacteria,4CZM6@85004|Bifidobacteriales 201174|Actinobacteria S GtrA-like protein - - - - - - - - - - - - GtrA JIJKFJGP_00667 552531.BIF_01351 5.83e-255 698.0 COG2852@1|root,COG2852@2|Bacteria,2GN40@201174|Actinobacteria,4D0JD@85004|Bifidobacteriales 201174|Actinobacteria S Protein conserved in bacteria - - - - - - - - - - - - DUF559 JIJKFJGP_00668 552531.BIF_01352 9.48e-83 244.0 COG1942@1|root,COG1942@2|Bacteria,2II0W@201174|Actinobacteria,4D0VC@85004|Bifidobacteriales 201174|Actinobacteria S Macrophage migration inhibitory factor (MIF) - - - - - - - - - - - - MIF JIJKFJGP_00669 552531.BIF_01353 0.0 990.0 COG2759@1|root,COG2759@2|Bacteria,2GT0X@201174|Actinobacteria,4CZ7P@85004|Bifidobacteriales 201174|Actinobacteria F Formate-tetrahydrofolate ligase fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS JIJKFJGP_00670 552531.BIF_01354 3.43e-281 769.0 COG1373@1|root,COG1373@2|Bacteria,2GK1Q@201174|Actinobacteria,4CZNQ@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 JIJKFJGP_00671 552531.BIF_01093 0.0 1109.0 COG4690@1|root,COG4690@2|Bacteria,2GM80@201174|Actinobacteria,4CZI5@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase family C69 pepD - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 JIJKFJGP_00672 552531.BIF_01092 0.0 1101.0 COG4690@1|root,COG4690@2|Bacteria,2GK57@201174|Actinobacteria,4D1XU@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase family C69 - - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 JIJKFJGP_00673 552531.BIF_00216 6.8e-181 503.0 COG1881@1|root,COG1881@2|Bacteria,2I5K1@201174|Actinobacteria,4CZSW@85004|Bifidobacteriales 201174|Actinobacteria S Phosphatidylethanolamine-binding protein - - - ko:K06910 - - - - ko00000 - - - PBP JIJKFJGP_00674 552531.BIF_00203 1.16e-285 783.0 COG0470@1|root,COG0470@2|Bacteria,2GJ8C@201174|Actinobacteria,4CZ4Y@85004|Bifidobacteriales 201174|Actinobacteria L DNA polymerase III holB GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C JIJKFJGP_00675 552531.BIF_01805 2.72e-142 402.0 COG0125@1|root,COG0125@2|Bacteria,2GNTI@201174|Actinobacteria,4CYQ8@85004|Bifidobacteriales 201174|Actinobacteria F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk - 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - - MFS_1,MFS_3,Thymidylate_kin JIJKFJGP_00676 552531.BIF_01023 0.0 1874.0 COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,2GJU7@201174|Actinobacteria,4CZ85@85004|Bifidobacteriales 201174|Actinobacteria L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,Toprim_C_rpt JIJKFJGP_00677 552531.BIF_00907 4.9e-281 771.0 COG0671@1|root,COG0671@2|Bacteria,2HIXE@201174|Actinobacteria,4CYS6@85004|Bifidobacteriales 201174|Actinobacteria I PAP2 superfamily - - - - - - - - - - - - PAP2 JIJKFJGP_00679 552531.BIF_00908 2.86e-274 753.0 COG1260@1|root,COG1260@2|Bacteria,2GKHB@201174|Actinobacteria,4D02Z@85004|Bifidobacteriales 201174|Actinobacteria I Myo-inositol-1-phosphate synthase ino1 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 ko:K01858 ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130 - R07324 RC01804 ko00000,ko00001,ko01000 - - - Inos-1-P_synth JIJKFJGP_00680 552531.BIF_00763 0.0 1347.0 COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4CZQZ@85004|Bifidobacteriales 201174|Actinobacteria M Transglycosylase pbp5 - - - - - - - - - - - Transgly,Transpeptidase JIJKFJGP_00681 552531.BIF_01494 0.0 1273.0 COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,4CZYW@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA GO:0000287,GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0030145,GO:0030955,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0046912,GO:0046914,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer JIJKFJGP_00682 552531.BIF_01495 1.7e-155 436.0 2C7PT@1|root,2ZXN2@2|Bacteria,2GM64@201174|Actinobacteria,4CYPY@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00683 552531.BIF_01496 2.38e-252 692.0 COG0136@1|root,COG0136@2|Bacteria,2GJJ8@201174|Actinobacteria,4CZPY@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv3708c Semialdhyde_dh,Semialdhyde_dhC JIJKFJGP_00684 552531.BIF_01497 5.79e-126 359.0 COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,4D00P@85004|Bifidobacteriales 201174|Actinobacteria E ACT domain ask GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 JIJKFJGP_00685 552531.BIF_02134 2.52e-173 486.0 COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,4CYSD@85004|Bifidobacteriales 201174|Actinobacteria E Amino acid kinase family ask GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 JIJKFJGP_00686 552531.BIF_01499 8.17e-141 397.0 COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4CZRI@85004|Bifidobacteriales 201174|Actinobacteria L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - HHH,RecR,Toprim_4 JIJKFJGP_00687 552531.BIF_01500 0.0 1654.0 COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,4CZMY@85004|Bifidobacteriales 201174|Actinobacteria L DNA polymerase III subunit gamma tau dnaX GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 JIJKFJGP_00688 552531.BIF_01501 6.12e-98 286.0 2DRBM@1|root,33B4F@2|Bacteria,2HZRZ@201174|Actinobacteria,4D1G6@85004|Bifidobacteriales 201174|Actinobacteria S TIGRFAM helicase secretion neighborhood TadE-like protein - - - - - - - - - - - - Tad JIJKFJGP_00689 552531.BIF_00243 5.66e-74 223.0 COG4961@1|root,COG4961@2|Bacteria,2GT3N@201174|Actinobacteria,4D1E4@85004|Bifidobacteriales 201174|Actinobacteria U TadE-like protein - - - - - - - - - - - - TadE JIJKFJGP_00690 552531.BIF_00242 4.93e-52 165.0 2EHCF@1|root,33B4A@2|Bacteria,2GR72@201174|Actinobacteria,4D1FR@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF4244) - - - - - - - - - - - - DUF4244 JIJKFJGP_00691 552531.BIF_00600 3.93e-143 405.0 COG4965@1|root,COG4965@2|Bacteria,2I2IG@201174|Actinobacteria,4D2W6@85004|Bifidobacteriales 201174|Actinobacteria U Type II secretion system (T2SS), protein F - - - - - - - - - - - - T2SSF JIJKFJGP_00692 552531.BIF_00599 3.09e-151 428.0 COG4965@1|root,COG4965@2|Bacteria,2GRXU@201174|Actinobacteria,4D1A3@85004|Bifidobacteriales 201174|Actinobacteria U Type ii secretion system - - - ko:K12510 - - - - ko00000,ko02044 - - - - JIJKFJGP_00693 552531.BIF_00340 2.01e-291 800.0 COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4CZF2@85004|Bifidobacteriales 201174|Actinobacteria U Type II IV secretion system protein cpaF - - ko:K02283 - - - - ko00000,ko02035,ko02044 - - - T2SSE JIJKFJGP_00694 31954.BPSP_1027 6.77e-94 291.0 COG0455@1|root,COG0455@2|Bacteria,2HZIH@201174|Actinobacteria,4D0JG@85004|Bifidobacteriales 201174|Actinobacteria D bacterial-type flagellum organization - - - - - - - - - - - - ParA JIJKFJGP_00695 552531.BIF_01426 0.0 1463.0 COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,4CYXH@85004|Bifidobacteriales 201174|Actinobacteria P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N JIJKFJGP_00696 552531.BIF_01427 5.22e-262 716.0 COG0494@1|root,COG2062@1|root,COG0494@2|Bacteria,COG2062@2|Bacteria,2GNRV@201174|Actinobacteria,4CZ90@85004|Bifidobacteriales 201174|Actinobacteria LT Phosphoglycerate mutase family mutT - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - His_Phos_1,NUDIX JIJKFJGP_00697 552531.BIF_01267 2.45e-168 471.0 28MMU@1|root,2ZAXG@2|Bacteria,2HAD5@201174|Actinobacteria,4CZ1Q@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00698 552531.BIF_01268 5.67e-151 425.0 COG0035@1|root,COG0035@2|Bacteria,2GPJE@201174|Actinobacteria,4CYVS@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - - UPRTase JIJKFJGP_00699 552531.BIF_01269 3.02e-254 696.0 COG0584@1|root,COG0584@2|Bacteria,2GNM5@201174|Actinobacteria,4CYS4@85004|Bifidobacteriales 201174|Actinobacteria C Glycerophosphoryl diester phosphodiesterase family glpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD,Laminin_G_3 JIJKFJGP_00700 552531.BIF_01270 0.0 1365.0 COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4CZ45@85004|Bifidobacteriales 201174|Actinobacteria S ABC1 family - - - ko:K03688 - - - - ko00000 - - - ABC1 JIJKFJGP_00701 552531.BIF_00784 3.85e-69 210.0 COG3937@1|root,COG3937@2|Bacteria,2GS3M@201174|Actinobacteria,4D1FE@85004|Bifidobacteriales 201174|Actinobacteria S granule-associated protein - - - - - - - - - - - - Phasin JIJKFJGP_00702 552531.BIF_00785 6.15e-183 508.0 COG3442@1|root,COG3442@2|Bacteria,2GKPV@201174|Actinobacteria,4CZJ1@85004|Bifidobacteriales 201174|Actinobacteria S CobB/CobQ-like glutamine amidotransferase domain cobQ2 - - ko:K07009 - - - - ko00000 - - - GATase_3 JIJKFJGP_00703 552531.BIF_00786 0.0 980.0 COG0771@1|root,COG0771@2|Bacteria,2GK18@201174|Actinobacteria,4CYTP@85004|Bifidobacteriales 201174|Actinobacteria M Domain of unknown function (DUF1727) murE - - - - - - - - - - - DUF1727,Mur_ligase_M JIJKFJGP_00704 552531.BIF_01436 0.0 896.0 COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria,4CYY3@85004|Bifidobacteriales 201174|Actinobacteria L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C JIJKFJGP_00705 552531.BIF_01435 3.38e-51 162.0 COG3620@1|root,COG3620@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - - - - - - - - - - HTH_3,HTH_31,HTH_37 JIJKFJGP_00706 552531.BIF_01434 0.0 1197.0 COG2844@1|root,COG2844@2|Bacteria,2GMKT@201174|Actinobacteria,4D07P@85004|Bifidobacteriales 201174|Actinobacteria O Nucleotidyltransferase domain glnD GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,HD,NTP_transf_2 JIJKFJGP_00707 552531.BIF_01433 6.28e-73 219.0 COG0347@1|root,COG0347@2|Bacteria,2IKN1@201174|Actinobacteria,4D0VD@85004|Bifidobacteriales 201174|Actinobacteria K Nitrogen regulatory protein P-II glnB GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K04751 ko02020,map02020 - - - ko00000,ko00001 - - - P-II JIJKFJGP_00708 552531.BIF_01432 1.79e-300 826.0 COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4CZA0@85004|Bifidobacteriales 201174|Actinobacteria U Ammonium Transporter Family amt - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp JIJKFJGP_00709 552531.BIF_01431 1.95e-301 828.0 COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria,4CZZX@85004|Bifidobacteriales 201174|Actinobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ftsY GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N JIJKFJGP_00710 552531.BIF_01293 7.53e-156 438.0 COG1309@1|root,COG1309@2|Bacteria,2GMBW@201174|Actinobacteria,4CYUD@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory proteins, tetR family icaR - - - - - - - - - - - TetR_N JIJKFJGP_00711 552531.BIF_01294 0.0 1069.0 COG4690@1|root,COG4690@2|Bacteria,2GM80@201174|Actinobacteria,4CYT0@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase family C69 - - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 JIJKFJGP_00713 552531.BIF_01295 6.61e-147 416.0 2B3XD@1|root,31WMC@2|Bacteria,2GXIN@201174|Actinobacteria,4D1NK@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00714 35760.BCHO_0213 9.61e-43 151.0 COG1309@1|root,COG1309@2|Bacteria,2IS1Z@201174|Actinobacteria,4D1PQ@85004|Bifidobacteriales 201174|Actinobacteria K transcriptional regulator - - - - - - - - - - - - - JIJKFJGP_00715 552531.BIF_02214 6.48e-213 600.0 COG4667@1|root,COG4667@2|Bacteria,2I8R7@201174|Actinobacteria,4D1W1@85004|Bifidobacteriales 201174|Actinobacteria S esterase of the alpha-beta hydrolase superfamily - - - - - - - - - - - - Patatin JIJKFJGP_00716 1435051.BMOU_0733 2.93e-230 652.0 COG0803@1|root,COG3443@1|root,COG0803@2|Bacteria,COG3443@2|Bacteria,2GM1K@201174|Actinobacteria,4D07D@85004|Bifidobacteriales 201174|Actinobacteria P ZinT (YodA) periplasmic lipocalin-like zinc-recruitment - - - ko:K02077,ko:K09815 ko02010,map02010 M00242,M00244 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ZinT,ZnuA JIJKFJGP_00717 552531.BIF_01133 0.0 974.0 COG1129@1|root,COG1129@2|Bacteria,2I2G1@201174|Actinobacteria,4CZ58@85004|Bifidobacteriales 201174|Actinobacteria G ATPases associated with a variety of cellular activities - - - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran JIJKFJGP_00718 552531.BIF_01134 7.69e-171 477.0 COG0619@1|root,COG0619@2|Bacteria,2IDZ2@201174|Actinobacteria,4D0CV@85004|Bifidobacteriales 201174|Actinobacteria P Cobalt transport protein - - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ JIJKFJGP_00719 552531.BIF_01135 2.58e-139 395.0 2BY0N@1|root,321KG@2|Bacteria,2IEYW@201174|Actinobacteria,4CZZD@85004|Bifidobacteriales 201174|Actinobacteria S Hypothetical bacterial integral membrane protein (Trep_Strep) - - - ko:K16926 - M00582 - - ko00000,ko00002,ko02000 3.A.1.31 - - Trep_Strep JIJKFJGP_00720 552531.BIF_00931 0.0 1662.0 COG1511@1|root,COG1511@2|Bacteria,2GKEM@201174|Actinobacteria,4CZ9R@85004|Bifidobacteriales 201174|Actinobacteria S YhgE Pip domain protein - - - ko:K01421 - - - - ko00000 - - - ABC2_membrane,ABC2_membrane_3 JIJKFJGP_00721 552531.BIF_01355 0.0 1291.0 COG1511@1|root,COG1511@2|Bacteria,2GKEM@201174|Actinobacteria,4CZ2A@85004|Bifidobacteriales 201174|Actinobacteria S YhgE Pip domain protein - - - ko:K01421 - - - - ko00000 - - - ABC2_membrane,ABC2_membrane_3,DUF3533 JIJKFJGP_00722 552531.BIF_01356 2.75e-136 387.0 COG1309@1|root,COG1309@2|Bacteria,2HZI8@201174|Actinobacteria,4D0IS@85004|Bifidobacteriales 201174|Actinobacteria K Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - TetR_C_9,TetR_N JIJKFJGP_00723 552531.BIF_01357 1.16e-292 801.0 COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4CZSH@85004|Bifidobacteriales 201174|Actinobacteria E Receptor family ligand binding region livK - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 JIJKFJGP_00724 552531.BIF_01359 1.34e-98 286.0 2BGPU@1|root,32ANQ@2|Bacteria,2GQ6E@201174|Actinobacteria,4D19U@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00725 552531.BIF_01360 6.76e-151 427.0 COG0110@1|root,COG0110@2|Bacteria,2GNUB@201174|Actinobacteria,4CZ5H@85004|Bifidobacteriales 201174|Actinobacteria S Maltose acetyltransferase - - 2.3.1.18,2.3.1.79 ko:K00633,ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac JIJKFJGP_00726 552531.BIF_02213 5.42e-158 443.0 COG0671@1|root,COG0671@2|Bacteria,2I9FB@201174|Actinobacteria,4D0X1@85004|Bifidobacteriales 201174|Actinobacteria I Acid phosphatase homologues - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 JIJKFJGP_00727 552531.BIF_00058 0.0 965.0 COG0726@1|root,COG0726@2|Bacteria,2HEQK@201174|Actinobacteria,4D2RD@85004|Bifidobacteriales 201174|Actinobacteria G Polysaccharide deacetylase - - 3.5.1.104 ko:K22278 - - - - ko00000,ko01000 - - - Polysacc_deac_1 JIJKFJGP_00728 552531.BIF_00689 0.0 1200.0 COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CZTU@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter transmembrane region - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran JIJKFJGP_00729 552531.BIF_01274 0.0 1206.0 COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CYYV@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter, ATP-binding protein - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran JIJKFJGP_00730 552531.BIF_01273 7.97e-137 387.0 COG1846@1|root,COG1846@2|Bacteria,2IMKE@201174|Actinobacteria,4CYZZ@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - HTH_34,MarR JIJKFJGP_00731 552531.BIF_02211 8.06e-96 279.0 COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4CZ04@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter, ATP-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran JIJKFJGP_00732 552531.BIF_01271 0.0 1091.0 COG4591@1|root,COG4591@2|Bacteria,2I6IU@201174|Actinobacteria,4D2YQ@85004|Bifidobacteriales 201174|Actinobacteria M MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD JIJKFJGP_00734 552531.BIF_02210 1.08e-43 142.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD JIJKFJGP_00735 552531.BIF_01601 0.0 979.0 COG1113@1|root,COG1113@2|Bacteria,2GJ0X@201174|Actinobacteria,4CZAY@85004|Bifidobacteriales 201174|Actinobacteria E Amino acid permease - - - ko:K03293 - - - - ko00000 2.A.3.1 - - AA_permease JIJKFJGP_00736 552531.BIF_01602 0.0 1840.0 COG0577@1|root,COG1511@1|root,COG0577@2|Bacteria,COG1511@2|Bacteria,2I2FK@201174|Actinobacteria,4CZJR@85004|Bifidobacteriales 201174|Actinobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX JIJKFJGP_00737 552531.BIF_01603 5.82e-165 461.0 COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria,4CYT2@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran JIJKFJGP_00739 552531.BIF_01605 0.0 957.0 COG1113@1|root,COG1113@2|Bacteria,2GJ0X@201174|Actinobacteria,4CZ4X@85004|Bifidobacteriales 201174|Actinobacteria E aromatic amino acid transport protein AroP K03293 aroP - - ko:K03293,ko:K11732 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.1 - - AA_permease JIJKFJGP_00740 552531.BIF_01606 1.42e-187 523.0 COG0390@1|root,COG0390@2|Bacteria,2GMHX@201174|Actinobacteria,4CYRQ@85004|Bifidobacteriales 201174|Actinobacteria V Uncharacterised protein family (UPF0014) - - - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 JIJKFJGP_00741 552531.BIF_01969 8.53e-172 481.0 COG1136@1|root,COG1136@2|Bacteria,2I8QP@201174|Actinobacteria,4CZZG@85004|Bifidobacteriales 201174|Actinobacteria V ATPases associated with a variety of cellular activities - - - ko:K02068 - M00211 - - ko00000,ko00002,ko02000 - - - ABC_tran JIJKFJGP_00742 552531.BIF_02126 0.0 893.0 COG2942@1|root,COG2942@2|Bacteria,2GMJ7@201174|Actinobacteria,4CZNY@85004|Bifidobacteriales 201174|Actinobacteria G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) - - - - - - - - - - - - GlcNAc_2-epim JIJKFJGP_00743 552531.BIF_01190 5.24e-34 116.0 2BHA3@1|root,32BBN@2|Bacteria,2GWW1@201174|Actinobacteria,4D1R7@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00744 552531.BIF_01189 3.02e-171 478.0 2E401@1|root,32YWY@2|Bacteria,2IE7W@201174|Actinobacteria,4CZYJ@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00745 552531.BIF_01188 2.49e-148 418.0 COG5578@1|root,COG5578@2|Bacteria,2IGDH@201174|Actinobacteria,4D0WB@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function, DUF624 - - - - - - - - - - - - DUF624 JIJKFJGP_00746 552531.BIF_01187 5.1e-240 660.0 COG1609@1|root,COG1609@2|Bacteria,2GJHF@201174|Actinobacteria,4CZCC@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - - - - - - - - - - LacI,Peripla_BP_3 JIJKFJGP_00747 552531.BIF_00019 2.28e-175 489.0 COG3250@1|root,COG3250@2|Bacteria,2GM69@201174|Actinobacteria,4D09M@85004|Bifidobacteriales 201174|Actinobacteria G beta-mannosidase - - 3.2.1.25 ko:K01192 ko00511,ko04142,map00511,map04142 - - - ko00000,ko00001,ko01000 - - - Glyco_hydro_2 JIJKFJGP_00748 552531.BIF_02125 0.0 974.0 COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria,4CYPX@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 1 bglA - 3.2.1.21 ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - - - Glyco_hydro_1 JIJKFJGP_00749 552531.BIF_02124 3.67e-281 766.0 COG2755@1|root,COG2755@2|Bacteria,2H9RY@201174|Actinobacteria,4D06T@85004|Bifidobacteriales 201174|Actinobacteria E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2,RicinB_lectin_2 JIJKFJGP_00750 552531.BIF_00477 0.0 1167.0 COG2755@1|root,COG2755@2|Bacteria,2I2FJ@201174|Actinobacteria,4D2US@85004|Bifidobacteriales 201174|Actinobacteria E Carbohydrate esterase, sialic acid-specific acetylesterase - - 3.1.1.53 ko:K05970 - - - - ko00000,ko01000 - - - SASA JIJKFJGP_00752 552531.BIF_01396 1.53e-258 711.0 COG0059@1|root,COG0059@2|Bacteria,2GKXA@201174|Actinobacteria,4CZBR@85004|Bifidobacteriales 201174|Actinobacteria H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN JIJKFJGP_00753 552531.BIF_01395 0.0 898.0 COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4CYY8@85004|Bifidobacteriales 201174|Actinobacteria EGP Sugar (and other) transporter - - - - - - - - - - - - MFS_1,Sugar_tr JIJKFJGP_00755 552531.BIF_01394 2.26e-64 196.0 2B12Y@1|root,30DWC@2|Bacteria,2GWJ2@201174|Actinobacteria,4D1TU@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF1778) - - - - - - - - - - - - DUF1778 JIJKFJGP_00756 552531.BIF_01393 5.95e-121 345.0 COG3153@1|root,COG3153@2|Bacteria,2I3WH@201174|Actinobacteria,4D2W8@85004|Bifidobacteriales 201174|Actinobacteria S Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_7 JIJKFJGP_00757 552531.BIF_01392 0.0 959.0 COG2211@1|root,COG2211@2|Bacteria,2GJZG@201174|Actinobacteria,4CZ93@85004|Bifidobacteriales 201174|Actinobacteria G Transporter major facilitator family protein scrT - - - - - - - - - - - MFS_1,MFS_2 JIJKFJGP_00758 552531.BIF_01419 3.05e-234 644.0 2DB6N@1|root,2Z7HZ@2|Bacteria,2I96Y@201174|Actinobacteria,4CZFN@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4392) - - - - - - - - - - - - DUF4392 JIJKFJGP_00759 552531.BIF_01420 6.55e-309 842.0 COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4CZ6Q@85004|Bifidobacteriales 201174|Actinobacteria I Biotin carboxylase C-terminal domain accBC3 - 6.3.4.14,6.4.1.2,6.4.1.3 ko:K11263 ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00741 R00742,R01859,R04385 RC00040,RC00097,RC00253,RC00367,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 JIJKFJGP_00760 552531.BIF_01421 9.6e-144 408.0 COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4CZSH@85004|Bifidobacteriales 201174|Actinobacteria E Receptor family ligand binding region livK - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 JIJKFJGP_00761 552531.BIF_01422 0.0 1023.0 COG2211@1|root,COG2211@2|Bacteria,2GJZG@201174|Actinobacteria,4CZ93@85004|Bifidobacteriales 201174|Actinobacteria G Transporter major facilitator family protein - - - - - - - - - - - - MFS_1 JIJKFJGP_00762 552531.BIF_02090 0.0 1026.0 COG0366@1|root,COG0366@2|Bacteria,2GNEC@201174|Actinobacteria,4CZ4T@85004|Bifidobacteriales 201174|Actinobacteria G Domain of unknown function (DUF1964) gtfA - 2.4.1.7 ko:K00690 ko00500,map00500 - R00803 RC00028 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF1964 JIJKFJGP_00763 552531.BIF_01423 1e-244 676.0 COG1609@1|root,COG1609@2|Bacteria,2GMHV@201174|Actinobacteria,4CZ3G@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - ko:K03484 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 JIJKFJGP_00764 552531.BIF_01216 1.73e-287 787.0 COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4CZSH@85004|Bifidobacteriales 201174|Actinobacteria E Receptor family ligand binding region livK - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 JIJKFJGP_00765 552531.BIF_01217 6.62e-194 538.0 COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4CZE0@85004|Bifidobacteriales 201174|Actinobacteria E ATPases associated with a variety of cellular activities livF - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran JIJKFJGP_00766 1435051.BMOU_1388 1.67e-202 564.0 COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4CZBX@85004|Bifidobacteriales 201174|Actinobacteria E Branched-chain amino acid ATP-binding cassette transporter - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C JIJKFJGP_00767 552531.BIF_01219 6.84e-210 583.0 COG4177@1|root,COG4177@2|Bacteria,2GJB3@201174|Actinobacteria,4CYTE@85004|Bifidobacteriales 201174|Actinobacteria U Belongs to the binding-protein-dependent transport system permease family livM - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 JIJKFJGP_00768 552531.BIF_01442 2.82e-306 840.0 COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria,4CZQ6@85004|Bifidobacteriales 201174|Actinobacteria U Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997,ko:K11956 ko02010,ko02024,map02010,map02024 M00237,M00322 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4,3.A.1.4.2,3.A.1.4.6 - - BPD_transp_2,CarboxypepD_reg JIJKFJGP_00769 552531.BIF_01440 7.85e-84 247.0 COG0239@1|root,COG0239@2|Bacteria,2IC26@201174|Actinobacteria,4D14T@85004|Bifidobacteriales 201174|Actinobacteria U Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB JIJKFJGP_00770 552531.BIF_01439 3.73e-224 618.0 COG0239@1|root,COG0239@2|Bacteria,2IC26@201174|Actinobacteria,4D0RK@85004|Bifidobacteriales 201174|Actinobacteria U Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB JIJKFJGP_00771 552531.BIF_01438 0.0 863.0 COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,4CZ0U@85004|Bifidobacteriales 201174|Actinobacteria F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt JIJKFJGP_00772 552531.BIF_01437 8.45e-249 683.0 COG0191@1|root,COG0191@2|Bacteria,2GM5P@201174|Actinobacteria,4CZJI@85004|Bifidobacteriales 201174|Actinobacteria G Fructose-bisphosphate aldolase class-II fbaA - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase JIJKFJGP_00773 552531.BIF_00991 0.0 881.0 COG0726@1|root,COG0726@2|Bacteria,2GN6G@201174|Actinobacteria,4D08Y@85004|Bifidobacteriales 201174|Actinobacteria G Polysaccharide deacetylase - - 3.2.1.8,3.5.1.104 ko:K01181,ko:K22278 - - - - ko00000,ko01000 - - - Polysacc_deac_1 JIJKFJGP_00774 552531.BIF_02207 2.86e-213 589.0 COG0583@1|root,COG0583@2|Bacteria,2GK13@201174|Actinobacteria,4CZKC@85004|Bifidobacteriales 201174|Actinobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate JIJKFJGP_00775 552531.BIF_00993 7.83e-262 717.0 COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4CZJY@85004|Bifidobacteriales 201174|Actinobacteria C Zinc-binding dehydrogenase adh - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_N_assoc,ADH_zinc_N JIJKFJGP_00776 552531.BIF_00461 3.29e-189 525.0 COG0702@1|root,COG0702@2|Bacteria,2ID6I@201174|Actinobacteria,4CZ41@85004|Bifidobacteriales 201174|Actinobacteria GM NmrA-like family - - - - - - - - - - - - NAD_binding_10 JIJKFJGP_00777 552531.BIF_00462 1.97e-111 320.0 COG0716@1|root,COG0716@2|Bacteria,2IK2W@201174|Actinobacteria,4D0WK@85004|Bifidobacteriales 201174|Actinobacteria C Flavodoxin - - - - - - - - - - - - Flavodoxin_4 JIJKFJGP_00778 864563.HMPREF9166_0397 1.47e-51 167.0 COG0789@1|root,COG0789@2|Bacteria,1V6C0@1239|Firmicutes,4H4U9@909932|Negativicutes 909932|Negativicutes K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 JIJKFJGP_00779 552531.BIF_02032 1.47e-120 348.0 COG0716@1|root,COG0716@2|Bacteria,2IGVN@201174|Actinobacteria,4D194@85004|Bifidobacteriales 201174|Actinobacteria C Flavodoxin - - - - - - - - - - - - Flavodoxin_4 JIJKFJGP_00780 552531.BIF_00724 0.0 868.0 COG4097@1|root,COG4097@2|Bacteria,2IDHN@201174|Actinobacteria,4CZTY@85004|Bifidobacteriales 201174|Actinobacteria P nitric oxide dioxygenase activity - - - - - - - - - - - - FAD_binding_6,FAD_binding_8,NAD_binding_1 JIJKFJGP_00781 767029.HMPREF9154_2452 2.27e-05 47.4 COG0657@1|root,COG0657@2|Bacteria 2|Bacteria I acetylesterase activity - - - - - - - - - - - - Abhydrolase_3 JIJKFJGP_00782 552531.BIF_00723 1.43e-250 687.0 COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4CZPB@85004|Bifidobacteriales 201174|Actinobacteria C Aldo/keto reductase family - - 1.1.1.91 ko:K05882 - - - - ko00000,ko01000 - - - Aldo_ket_red JIJKFJGP_00783 552531.BIF_00364 5.51e-206 570.0 COG0583@1|root,COG0583@2|Bacteria,2GK13@201174|Actinobacteria,4CZ74@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate JIJKFJGP_00784 552531.BIF_01581 2.08e-244 670.0 COG1073@1|root,COG1073@2|Bacteria,2GNB6@201174|Actinobacteria,4CZW3@85004|Bifidobacteriales 201174|Actinobacteria S Dienelactone hydrolase family - - - ko:K06889 - - - - ko00000 - - - DLH,Peptidase_S15 JIJKFJGP_00785 552531.BIF_02206 1.13e-111 321.0 COG1917@1|root,COG1917@2|Bacteria,2IFSF@201174|Actinobacteria,4D13U@85004|Bifidobacteriales 201174|Actinobacteria S Cupin domain - - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD,Cupin_2 JIJKFJGP_00786 552531.BIF_02205 1.87e-181 506.0 COG0599@1|root,COG0599@2|Bacteria,2GITB@201174|Actinobacteria,4CZBK@85004|Bifidobacteriales 201174|Actinobacteria S Carboxymuconolactone decarboxylase family - - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - Abhydrolase_1,CMD JIJKFJGP_00787 552531.BIF_01583 0.0 934.0 COG4447@1|root,COG4447@2|Bacteria,2IKAH@201174|Actinobacteria,4D254@85004|Bifidobacteriales 201174|Actinobacteria S cellulose binding - - - - - - - - - - - - - JIJKFJGP_00788 552531.BIF_01584 2.39e-113 325.0 COG0350@1|root,COG0350@2|Bacteria,2IHXW@201174|Actinobacteria,4D10F@85004|Bifidobacteriales 201174|Actinobacteria L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated ogt GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 ko:K00567,ko:K07443 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N JIJKFJGP_00789 552531.BIF_01585 8.74e-69 208.0 COG3077@1|root,COG3077@2|Bacteria,2IS3T@201174|Actinobacteria,4D16X@85004|Bifidobacteriales 201174|Actinobacteria L RelB antitoxin - - - ko:K07473 - - - - ko00000,ko02048 - - - RelB JIJKFJGP_00790 1232428.CAVO010000037_gene1229 2.14e-14 71.2 COG0655@1|root,COG0655@2|Bacteria,1V5J1@1239|Firmicutes,4H4HX@909932|Negativicutes 909932|Negativicutes S NADPH-dependent FMN reductase - - - - - - - - - - - - FMN_red JIJKFJGP_00791 552531.BIF_01587 4.63e-293 800.0 COG0477@1|root,COG2814@2|Bacteria,2GK8C@201174|Actinobacteria,4CZ46@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily - - - ko:K08156,ko:K19577 - - - - ko00000,ko02000 2.A.1.2.14,2.A.1.2.65 - - MFS_1 JIJKFJGP_00792 552531.BIF_02033 8.61e-158 442.0 COG2135@1|root,COG2135@2|Bacteria,2HXXX@201174|Actinobacteria,4D02S@85004|Bifidobacteriales 201174|Actinobacteria E SOS response associated peptidase (SRAP) - - - - - - - - - - - - SRAP JIJKFJGP_00793 552531.BIF_01588 6.74e-271 743.0 COG2367@1|root,COG2367@2|Bacteria,2IA8N@201174|Actinobacteria,4CZV1@85004|Bifidobacteriales 201174|Actinobacteria V Beta-lactamase - - - - - - - - - - - - Beta-lactamase2 JIJKFJGP_00794 552531.BIF_01589 1.98e-232 639.0 COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4CYVY@85004|Bifidobacteriales 201174|Actinobacteria O Belongs to the peptidase M48B family htpX GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 JIJKFJGP_00796 552531.BIF_01590 0.0 959.0 COG0343@1|root,COG0343@2|Bacteria,2GMWY@201174|Actinobacteria,4CZNX@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt - 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT JIJKFJGP_00797 552531.BIF_01591 0.0 1057.0 COG0790@1|root,COG0790@2|Bacteria,2GTVX@201174|Actinobacteria,4D1KI@85004|Bifidobacteriales 201174|Actinobacteria S Sel1-like repeats. - - - ko:K07126 - - - - ko00000 - - - Sel1 JIJKFJGP_00798 552531.BIF_01958 6.47e-149 418.0 COG1011@1|root,COG1011@2|Bacteria,2I8XE@201174|Actinobacteria,4D00B@85004|Bifidobacteriales 201174|Actinobacteria S Haloacid dehalogenase-like hydrolase - - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2,Hydrolase JIJKFJGP_00799 552531.BIF_00686 0.0 1111.0 COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CZAP@85004|Bifidobacteriales 201174|Actinobacteria O Domain present in PSD-95, Dlg, and ZO-1/2. degP - - ko:K08372 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ_2,Trypsin_2 JIJKFJGP_00800 552531.BIF_01137 0.0 1405.0 COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4CZ4F@85004|Bifidobacteriales 201174|Actinobacteria P E1-E2 ATPase - - 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,Hemerythrin,Hydrolase JIJKFJGP_00801 552531.BIF_01138 0.0 967.0 COG0493@1|root,COG0493@2|Bacteria,2GJ4A@201174|Actinobacteria,4CZIT@85004|Bifidobacteriales 201174|Actinobacteria C Pyridine nucleotide-disulphide oxidoreductase fprA - 1.18.1.2,1.19.1.1 ko:K00528 - - R10159 - ko00000,ko01000 - - - Pyr_redox_2 JIJKFJGP_00803 552531.BIF_01957 4.74e-48 154.0 COG2261@1|root,COG2261@2|Bacteria,2GSMF@201174|Actinobacteria,4D1J1@85004|Bifidobacteriales 201174|Actinobacteria S Transglycosylase associated protein - - - - - - - - - - - - Transgly_assoc JIJKFJGP_00804 552531.BIF_01956 4.12e-47 151.0 COG2261@1|root,COG2261@2|Bacteria,2H9M0@201174|Actinobacteria,4D2G1@85004|Bifidobacteriales 201174|Actinobacteria S Transglycosylase associated protein - - - - - - - - - - - - Transgly_assoc JIJKFJGP_00805 552531.BIF_01506 1.39e-229 632.0 COG0500@1|root,COG2226@2|Bacteria,2HCAN@201174|Actinobacteria,4D0C9@85004|Bifidobacteriales 201174|Actinobacteria Q Methyltransferase domain rrmA GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052912,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.187 ko:K00563 - - R07233 RC00003 ko00000,ko01000,ko03009 - - - Methyltransf_11,Methyltransf_25 JIJKFJGP_00806 552531.BIF_01505 3.36e-77 229.0 2B96S@1|root,322HZ@2|Bacteria,2H6X7@201174|Actinobacteria,4D2CX@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00807 552531.BIF_01504 1.54e-271 741.0 COG2267@1|root,COG2267@2|Bacteria,2HZ9U@201174|Actinobacteria,4CZ5E@85004|Bifidobacteriales 201174|Actinobacteria I Serine aminopeptidase, S33 pldB - 3.1.1.5 ko:K01048 ko00564,map00564 - - - ko00000,ko00001,ko01000 - - - Hydrolase_4 JIJKFJGP_00808 1690.BPSG_1193 5.05e-161 460.0 COG0697@1|root,COG0697@2|Bacteria,2HZCH@201174|Actinobacteria,4CZRZ@85004|Bifidobacteriales 201174|Actinobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA JIJKFJGP_00809 552531.BIF_01502 0.0 1627.0 COG1506@1|root,COG1506@2|Bacteria,2GJ6A@201174|Actinobacteria,4CZAE@85004|Bifidobacteriales 201174|Actinobacteria E Dipeptidyl peptidase IV (DPP IV) N-terminal region pepX - 3.4.14.5 ko:K01278 ko04974,map04974 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - DPPIV_N,PD40,Peptidase_S9 JIJKFJGP_00810 552531.BIF_01067 1.83e-167 468.0 COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4CYUI@85004|Bifidobacteriales 201174|Actinobacteria T Protein of unknown function (DUF2662) fhaA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - - - - - - - - - - DUF3662,FHA,Yop-YscD_cpl JIJKFJGP_00811 552531.BIF_01059 2.44e-94 278.0 COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,4D0RN@85004|Bifidobacteriales 201174|Actinobacteria T Inner membrane component of T3SS, cytoplasmic domain fhaB GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944 - - - - - - - - - - FHA,Yop-YscD_cpl JIJKFJGP_00812 552531.BIF_01058 0.0 942.0 COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4CZDN@85004|Bifidobacteriales 201174|Actinobacteria T Sigma factor PP2C-like phosphatases pstP GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 JIJKFJGP_00813 552531.BIF_01057 0.0 1035.0 COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4CZ67@85004|Bifidobacteriales 201174|Actinobacteria D Belongs to the SEDS family rodA GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE JIJKFJGP_00814 552531.BIF_01570 0.0 946.0 COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria,4CYTI@85004|Bifidobacteriales 201174|Actinobacteria M penicillin-binding protein pbpA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K05364 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01011 - - - Transpeptidase JIJKFJGP_00815 552531.BIF_01569 1.37e-248 682.0 COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4CYUK@85004|Bifidobacteriales 201174|Actinobacteria T Protein tyrosine kinase pknA - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase JIJKFJGP_00816 552531.BIF_01568 0.0 1256.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4CZFU@85004|Bifidobacteriales 201174|Actinobacteria KLT Protein tyrosine kinase pknB GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase JIJKFJGP_00817 552531.BIF_01567 7.93e-156 437.0 COG0512@1|root,COG0512@2|Bacteria,2GJUX@201174|Actinobacteria,4D09E@85004|Bifidobacteriales 201174|Actinobacteria EH para-aminobenzoate synthase glutamine amidotransferase component II trpG GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85,4.1.3.27 ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase JIJKFJGP_00818 552531.BIF_01566 1.07e-285 779.0 COG3764@1|root,COG3764@2|Bacteria,2GKT6@201174|Actinobacteria,4CYZ5@85004|Bifidobacteriales 201174|Actinobacteria M Sortase family srtB - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase JIJKFJGP_00819 552531.BIF_01565 1.4e-177 503.0 COG3879@1|root,COG3879@2|Bacteria,2GJ9Y@201174|Actinobacteria,4CZ1A@85004|Bifidobacteriales 201174|Actinobacteria S Bacterial protein of unknown function (DUF881) - - - - - - - - - - - - DUF881 JIJKFJGP_00820 218140.BPSY_0628 2.13e-46 157.0 2E4NY@1|root,32ZHR@2|Bacteria,2GQPW@201174|Actinobacteria,4D0ZH@85004|Bifidobacteriales 201174|Actinobacteria D Involved in cell division crgA - - - - - - - - - - - CrgA JIJKFJGP_00821 552531.BIF_01564 0.0 974.0 COG0742@1|root,COG0742@2|Bacteria,2HZAY@201174|Actinobacteria,4CZEU@85004|Bifidobacteriales 201174|Actinobacteria L ribosomal rna small subunit methyltransferase - - - - - - - - - - - - Cons_hypoth95,Methyltransf_15,PCMT JIJKFJGP_00822 552531.BIF_00591 1.76e-164 462.0 COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria,4CZJ0@85004|Bifidobacteriales 201174|Actinobacteria S Rhomboid family gluP - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid,zf-B_box JIJKFJGP_00823 552531.BIF_01955 9.18e-49 155.0 2BFAJ@1|root,3293I@2|Bacteria,2ISGB@201174|Actinobacteria,4D185@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00824 552531.BIF_00871 0.0 1655.0 COG0058@1|root,COG0058@2|Bacteria,2GIVZ@201174|Actinobacteria,4CZ3V@85004|Bifidobacteriales 201174|Actinobacteria G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase JIJKFJGP_00825 552531.BIF_01021 3.73e-104 301.0 COG3255@1|root,COG3255@2|Bacteria,2IQBF@201174|Actinobacteria,4D10H@85004|Bifidobacteriales 201174|Actinobacteria I Sterol carrier protein - - - - - - - - - - - - MDMPI_C,MDMPI_N JIJKFJGP_00826 552531.BIF_01080 1.4e-66 203.0 2EGRW@1|root,32FNP@2|Bacteria,2HZNH@201174|Actinobacteria,4D120@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3073) - - - - - - - - - - - - DUF3073 JIJKFJGP_00827 552531.BIF_01081 2.9e-264 724.0 COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria,4CYXM@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b JIJKFJGP_00828 552531.BIF_01191 3.4e-105 306.0 COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,4D0QM@85004|Bifidobacteriales 201174|Actinobacteria K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0071944 - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N JIJKFJGP_00829 552531.BIF_01115 3.01e-120 343.0 COG0221@1|root,COG0221@2|Bacteria,2GM7F@201174|Actinobacteria,4CYWS@85004|Bifidobacteriales 201174|Actinobacteria C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions ppa GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944 3.6.1.1 ko:K01507 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - iNJ661.Rv3628 Pyrophosphatase JIJKFJGP_00830 552531.BIF_01519 0.0 1553.0 COG0366@1|root,COG0366@2|Bacteria,2GJKR@201174|Actinobacteria,4CZSK@85004|Bifidobacteriales 201174|Actinobacteria G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB glgE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.4.99.16 ko:K16147 ko00500,ko01100,map00500,map01100 - R09994 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3416 JIJKFJGP_00831 552531.BIF_01518 0.0 1394.0 COG5624@1|root,COG5624@2|Bacteria,2H7AK@201174|Actinobacteria,4CZMA@85004|Bifidobacteriales 201174|Actinobacteria K RNA polymerase II activating transcription factor binding - - - - - - - - - - - - - JIJKFJGP_00832 552531.BIF_01265 0.0 3492.0 COG4932@1|root,COG4932@2|Bacteria 2|Bacteria M domain protein - - - ko:K13735 ko05100,map05100 - - - ko00000,ko00001 - - - CHU_C,Cna_B,DUF11,Invasin_D3,PPC,Peptidase_M10_C,Reprolysin_4,SprB,VCBS JIJKFJGP_00833 552531.BIF_01266 0.0 1008.0 COG0038@1|root,COG0038@2|Bacteria,2HZBE@201174|Actinobacteria,4CZGS@85004|Bifidobacteriales 201174|Actinobacteria P Voltage gated chloride channel - - - - - - - - - - - - Voltage_CLC JIJKFJGP_00834 552531.BIF_00592 1.19e-32 124.0 COG0028@1|root,COG0028@2|Bacteria,2GM6Y@201174|Actinobacteria,4CZWD@85004|Bifidobacteriales 201174|Actinobacteria EH Thiamine pyrophosphate enzyme, central domain oxc - 4.1.1.8 ko:K01577 ko00630,ko01100,map00630,map01100 - R01908 RC00620 ko00000,ko00001,ko01000 - - iNJ661.Rv0118c TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N JIJKFJGP_00835 552531.BIF_00592 0.0 1066.0 COG0028@1|root,COG0028@2|Bacteria,2GM6Y@201174|Actinobacteria,4CZWD@85004|Bifidobacteriales 201174|Actinobacteria EH Thiamine pyrophosphate enzyme, central domain oxc - 4.1.1.8 ko:K01577 ko00630,ko01100,map00630,map01100 - R01908 RC00620 ko00000,ko00001,ko01000 - - iNJ661.Rv0118c TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N JIJKFJGP_00836 35760.BCHO_0618 5.91e-222 617.0 COG0679@1|root,COG0679@2|Bacteria,2GUU2@201174|Actinobacteria,4CYYA@85004|Bifidobacteriales 201174|Actinobacteria S Membrane transport protein - - - ko:K07088 - - - - ko00000 - - - Mem_trans JIJKFJGP_00837 552531.BIF_00941 4.97e-276 754.0 COG2730@1|root,COG2730@2|Bacteria,2GKTY@201174|Actinobacteria 201174|Actinobacteria G hydrolase family 5 - - 3.2.1.78 ko:K01218 ko00051,ko02024,map00051,map02024 - R01332 RC00467 ko00000,ko00001,ko01000 - GH26 - CBM_10,CBM_2,Cellulase JIJKFJGP_00838 552531.BIF_01176 0.0 914.0 COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4D07S@85004|Bifidobacteriales 201174|Actinobacteria C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate frc - 2.8.3.15,2.8.3.16 ko:K07544,ko:K07749 ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220 M00418 R05588 RC00014,RC00137 ko00000,ko00001,ko00002,ko01000 - - - CoA_transf_3 JIJKFJGP_00839 552531.BIF_01175 2.89e-292 798.0 COG0582@1|root,COG0582@2|Bacteria,2I0HN@201174|Actinobacteria,4D01V@85004|Bifidobacteriales 201174|Actinobacteria L Phage integrase family - - - - - - - - - - - - Phage_integrase JIJKFJGP_00840 552531.BIF_01894 1.17e-280 765.0 2DB9A@1|root,2Z7VI@2|Bacteria,2ICCG@201174|Actinobacteria,4D05W@85004|Bifidobacteriales 201174|Actinobacteria H Adenine-specific methyltransferase EcoRI - - - - - - - - - - - - EcoRI_methylase JIJKFJGP_00841 552531.BIF_00872 1.39e-284 775.0 COG1403@1|root,COG1479@1|root,COG1403@2|Bacteria,COG1479@2|Bacteria,2IE40@201174|Actinobacteria,4CYUJ@85004|Bifidobacteriales 201174|Actinobacteria L HNH endonuclease - - - - - - - - - - - - DUF262,HNH JIJKFJGP_00842 552531.BIF_02186 9.18e-49 155.0 2B2YQ@1|root,31VJP@2|Bacteria,2GVTB@201174|Actinobacteria,4D1F7@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00843 552531.BIF_00873 8.16e-159 450.0 2D82H@1|root,32TQ8@2|Bacteria,2IBXS@201174|Actinobacteria,4D05K@85004|Bifidobacteriales 201174|Actinobacteria S Plasmid replication protein - - - - - - - - - - - - Rep_2 JIJKFJGP_00844 552531.BIF_00874 9.79e-182 505.0 COG1674@1|root,COG1674@2|Bacteria,2HZGB@201174|Actinobacteria,4D0C7@85004|Bifidobacteriales 201174|Actinobacteria D ftsk spoiiie - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - - JIJKFJGP_00845 552531.BIF_00709 2.44e-86 255.0 2B530@1|root,31XW9@2|Bacteria,2GV6A@201174|Actinobacteria,4D1MU@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00846 78346.BRUM_1423 5.62e-37 124.0 2BKN1@1|root,32F3F@2|Bacteria,2GYH9@201174|Actinobacteria,4D1TA@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00847 552531.BIF_02162 2.08e-270 740.0 29ZXM@1|root,30MZ7@2|Bacteria,2ICGB@201174|Actinobacteria,4D0GZ@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00849 552531.BIF_01895 6.66e-235 645.0 COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,4CZIN@85004|Bifidobacteriales 201174|Actinobacteria F Inosine-uridine preferring nucleoside hydrolase rihB - 3.2.2.1,3.2.2.8 ko:K01239,ko:K01250,ko:K10213 ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100 - R01245,R01273,R01677,R01770,R02137,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro JIJKFJGP_00850 552531.BIF_00289 0.0 897.0 COG0477@1|root,COG2814@2|Bacteria,2H8UD@201174|Actinobacteria,4CZ16@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr JIJKFJGP_00851 552531.BIF_01336 1.61e-261 716.0 COG1897@1|root,COG1897@2|Bacteria,2GK5E@201174|Actinobacteria,4CZRK@85004|Bifidobacteriales 201174|Actinobacteria E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine metAA - 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - HTS JIJKFJGP_00852 552531.BIF_01337 3.54e-188 523.0 COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,4CYZD@85004|Bifidobacteriales 201174|Actinobacteria C it plays a direct role in the translocation of protons across the membrane atpB - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A JIJKFJGP_00853 1690.BPSG_0746 2.54e-42 139.0 COG0636@1|root,COG0636@2|Bacteria,2GQI6@201174|Actinobacteria,4D16J@85004|Bifidobacteriales 201174|Actinobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C JIJKFJGP_00854 552531.BIF_01338 2.71e-95 280.0 COG0711@1|root,COG0711@2|Bacteria,2GJS4@201174|Actinobacteria,4CYY5@85004|Bifidobacteriales 201174|Actinobacteria C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B JIJKFJGP_00855 552531.BIF_01339 7.19e-196 543.0 COG0712@1|root,COG0712@2|Bacteria,2GMJ5@201174|Actinobacteria,4CZ9V@85004|Bifidobacteriales 201174|Actinobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B,OSCP JIJKFJGP_00856 552531.BIF_01340 0.0 1066.0 COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,4CZI7@85004|Bifidobacteriales 201174|Actinobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N JIJKFJGP_00857 552531.BIF_00544 1.72e-213 590.0 COG0224@1|root,COG0224@2|Bacteria,2GJ7Q@201174|Actinobacteria,4CYVJ@85004|Bifidobacteriales 201174|Actinobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt JIJKFJGP_00858 552531.BIF_00327 0.0 981.0 COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,4CZGY@85004|Bifidobacteriales 201174|Actinobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N JIJKFJGP_00859 552531.BIF_01897 1.28e-65 199.0 COG0355@1|root,COG0355@2|Bacteria,2HZPJ@201174|Actinobacteria,4D16F@85004|Bifidobacteriales 201174|Actinobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC - - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE_N JIJKFJGP_00862 552531.BIF_00493 0.0 1321.0 COG0480@1|root,COG0480@2|Bacteria,2GJ64@201174|Actinobacteria,4CZM5@85004|Bifidobacteriales 201174|Actinobacteria J Elongation factor G, domain IV tetM - - ko:K18220 - - - - br01600,ko00000,ko01504 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU JIJKFJGP_00863 552531.BIF_00221 0.0 995.0 COG0531@1|root,COG0531@2|Bacteria,2H98W@201174|Actinobacteria,4CYSV@85004|Bifidobacteriales 201174|Actinobacteria E Amino acid permease lysI GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03758 - - - - ko00000,ko02000 2.A.3.2 - - AA_permease_2 JIJKFJGP_00864 552531.BIF_01108 1.13e-150 424.0 2B6WA@1|root,31ZW3@2|Bacteria,2H2W2@201174|Actinobacteria,4D24I@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00865 1690.BPSG_1511 3.18e-41 135.0 2BJAT@1|root,32DKQ@2|Bacteria,2GUII@201174|Actinobacteria,4D1K5@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00866 552531.BIF_01105 0.0 1103.0 COG4166@1|root,COG4166@2|Bacteria,2GIUH@201174|Actinobacteria,4CZFK@85004|Bifidobacteriales 201174|Actinobacteria E ABC transporter, substrate-binding protein, family 5 dppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 JIJKFJGP_00867 552531.BIF_01104 0.0 903.0 COG0477@1|root,COG2814@2|Bacteria,2GIZX@201174|Actinobacteria,4D0AC@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily - - - ko:K18926 - M00715 - - ko00000,ko00002,ko02000 2.A.1.3.30 - - MFS_1 JIJKFJGP_00868 552531.BIF_00549 3.33e-149 421.0 COG1842@1|root,COG1842@2|Bacteria,2GP0K@201174|Actinobacteria,4CYZE@85004|Bifidobacteriales 201174|Actinobacteria KT PspA/IM30 family pspA - - ko:K03969 - - - - ko00000 - - - PspA_IM30 JIJKFJGP_00869 552531.BIF_00550 8.06e-315 857.0 COG1512@1|root,COG1512@2|Bacteria,2IDTI@201174|Actinobacteria,4D0EZ@85004|Bifidobacteriales 201174|Actinobacteria S COG1512 Beta-propeller domains of methanol dehydrogenase type - - - - - - - - - - - - - JIJKFJGP_00870 1034345.CAEM01000065_gene1 2.01e-08 57.8 COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4CWP3@84998|Coriobacteriia 84998|Coriobacteriia L This gene contains a nucleotide ambiguity which may be the result of a sequencing error - - - - - - - - - - - - HTH_38,rve JIJKFJGP_00871 552531.BIF_01997 0.0 2289.0 COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4CYT7@85004|Bifidobacteriales 201174|Actinobacteria J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1 JIJKFJGP_00872 552531.BIF_01996 3.48e-33 114.0 2B5M6@1|root,31YG9@2|Bacteria,2H0R6@201174|Actinobacteria,4D1RX@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00873 552531.BIF_00228 1.7e-188 523.0 COG2365@1|root,COG2365@2|Bacteria,2GK28@201174|Actinobacteria,4D0S0@85004|Bifidobacteriales 201174|Actinobacteria T Tyrosine phosphatase family - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - Acetyltransf_10,Y_phosphatase3 JIJKFJGP_00874 1690.BPSG_1502 5.39e-62 190.0 2B2CA@1|root,31UWP@2|Bacteria,2GUKK@201174|Actinobacteria,4D1MT@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00875 1690.BPSG_1139 2.3e-22 88.2 2B3H5@1|root,31W65@2|Bacteria,2GWRQ@201174|Actinobacteria,4D1QX@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00876 31954.BPSP_1510 0.0 1311.0 COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CZPJ@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter transmembrane region - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran JIJKFJGP_00877 31954.BPSP_1509 0.0 1243.0 COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CZMX@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter, ATP-binding protein - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran JIJKFJGP_00878 552531.BIF_02179 6.41e-127 362.0 COG1846@1|root,COG1846@2|Bacteria,2IIWT@201174|Actinobacteria,4D0WT@85004|Bifidobacteriales 201174|Actinobacteria K MarR family - - - - - - - - - - - - MarR,MarR_2 JIJKFJGP_00879 31954.BPSP_1507 2.28e-132 375.0 COG0431@1|root,COG0431@2|Bacteria,2HZK7@201174|Actinobacteria,4D0RT@85004|Bifidobacteriales 201174|Actinobacteria S NADPH-dependent FMN reductase - - - - - - - - - - - - FMN_red JIJKFJGP_00880 552531.BIF_01536 1.31e-129 367.0 COG3727@1|root,COG3727@2|Bacteria,2IKPY@201174|Actinobacteria,4D0R6@85004|Bifidobacteriales 201174|Actinobacteria L May nick specific sequences that contain T G mispairs resulting from m5C-deamination vsr - - ko:K07458 - - - - ko00000,ko01000,ko03400 - - - Vsr JIJKFJGP_00883 552531.BIF_01991 6.34e-66 200.0 2BEPE@1|root,328F0@2|Bacteria,2HE7R@201174|Actinobacteria,4D2QI@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00884 552531.BIF_01990 4.02e-265 724.0 2EXKP@1|root,33QWM@2|Bacteria,2II2B@201174|Actinobacteria,4D0YQ@85004|Bifidobacteriales 201174|Actinobacteria - - - - - ko:K19133 - - - - ko00000,ko02048 - - - - JIJKFJGP_00885 552531.BIF_01989 0.0 2004.0 COG1203@1|root,COG1203@2|Bacteria,2I266@201174|Actinobacteria,4CZU7@85004|Bifidobacteriales 201174|Actinobacteria L CRISPR-associated helicase Cas3 cas3 - - ko:K07012 - - - - ko00000,ko01000,ko02048 - - - Helicase_C JIJKFJGP_00886 552531.BIF_01988 0.0 1108.0 2EXZN@1|root,33R8Q@2|Bacteria,2IDAW@201174|Actinobacteria,4D0SE@85004|Bifidobacteriales 201174|Actinobacteria - - - - - ko:K19132 - - - - ko00000,ko02048 - - - - JIJKFJGP_00887 552531.BIF_01987 5.26e-284 778.0 28KC2@1|root,2Z9Z2@2|Bacteria,2IAFZ@201174|Actinobacteria,4D0CU@85004|Bifidobacteriales 201174|Actinobacteria S CRISPR-associated protein GSU0053 (Cas_GSU0053) - - - ko:K19131 - - - - ko00000,ko02048 - - - Cas_GSU0053 JIJKFJGP_00888 356829.BITS_0808 7.49e-24 94.0 COG1343@1|root,COG1343@2|Bacteria,2GXKQ@201174|Actinobacteria,4D2E4@85004|Bifidobacteriales 201174|Actinobacteria L CRISPR associated protein Cas2 cas2 - - ko:K09951 - - - - ko00000,ko02048 - - - CRISPR_Cas2 JIJKFJGP_00889 552531.BIF_01985 0.0 1084.0 COG1468@1|root,COG1518@1|root,COG1468@2|Bacteria,COG1518@2|Bacteria,2I8M0@201174|Actinobacteria,4CZYS@85004|Bifidobacteriales 201174|Actinobacteria L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette cas1 - - ko:K15342 - - - - ko00000,ko02048,ko03400 - - - Cas_Cas1,Cas_Cas4 JIJKFJGP_00890 552531.BIF_00236 2.49e-279 763.0 COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria,4D03K@85004|Bifidobacteriales 201174|Actinobacteria O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG JIJKFJGP_00891 552531.BIF_00962 2.8e-256 703.0 COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,4CZK3@85004|Bifidobacteriales 201174|Actinobacteria K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03705 - - - - ko00000,ko03000 - - - HTH_DeoR,HrcA JIJKFJGP_00892 552531.BIF_00963 0.0 1420.0 COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,4CZ64@85004|Bifidobacteriales 201174|Actinobacteria H Belongs to the transketolase family tkt GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N JIJKFJGP_00893 552531.BIF_00287 9.8e-258 707.0 COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4CZ3J@85004|Bifidobacteriales 201174|Actinobacteria H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal - 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA JIJKFJGP_00894 552531.BIF_02249 3.06e-109 320.0 COG1357@1|root,COG1357@2|Bacteria,2HZNT@201174|Actinobacteria,4D135@85004|Bifidobacteriales 201174|Actinobacteria S PFAM Pentapeptide repeats (8 copies) - - - - - - - - - - - - Pentapeptide_4 JIJKFJGP_00895 552531.BIF_00086 4.1e-293 799.0 COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4CYVP@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase class I and II - - 2.6.1.1,2.6.1.2,2.6.1.66 ko:K00812,ko:K00841,ko:K08969,ko:K10907,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00034,M00525 R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R04467,R05052,R07396 RC00006,RC00008,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 JIJKFJGP_00896 552531.BIF_00343 1.01e-117 337.0 COG1522@1|root,COG1522@2|Bacteria,2H359@201174|Actinobacteria,4D0GY@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix ASNC type - - - - - - - - - - - - AsnC_trans_reg,HTH_24 JIJKFJGP_00897 552531.BIF_02076 0.0 1092.0 COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4CZVJ@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase, class I II aspC GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.6.1.1,2.6.1.2,2.6.1.66 ko:K00812,ko:K08969,ko:K10907,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00034 R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052,R07396 RC00006,RC00008,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - iNJ661.Rv0337c Aminotran_1_2 JIJKFJGP_00898 552531.BIF_00160 7.54e-207 571.0 COG0561@1|root,COG0561@2|Bacteria,2HZYB@201174|Actinobacteria,4CZQW@85004|Bifidobacteriales 201174|Actinobacteria S Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 JIJKFJGP_00899 552531.BIF_01902 2.87e-43 142.0 COG1314@1|root,COG1314@2|Bacteria,2GR31@201174|Actinobacteria,4D16U@85004|Bifidobacteriales 201174|Actinobacteria U Preprotein translocase SecG subunit secG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG JIJKFJGP_00900 552531.BIF_01901 2.06e-194 540.0 COG0149@1|root,COG0149@2|Bacteria,2GJXZ@201174|Actinobacteria,4CYSG@85004|Bifidobacteriales 201174|Actinobacteria G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM JIJKFJGP_00901 552531.BIF_00277 2.34e-284 777.0 COG0126@1|root,COG0126@2|Bacteria,2GJC6@201174|Actinobacteria,4CZJ3@85004|Bifidobacteriales 201174|Actinobacteria F Phosphoglycerate kinase pgk GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK JIJKFJGP_00902 552531.BIF_00278 2.67e-224 619.0 COG1481@1|root,COG1481@2|Bacteria,2GJZU@201174|Actinobacteria,4CYTD@85004|Bifidobacteriales 201174|Actinobacteria K May be required for sporulation whiA GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944 - ko:K09762 - - - - ko00000 - - - HTH_WhiA,LAGLIDADG_WhiA,WhiA_N JIJKFJGP_00903 552531.BIF_00539 1.72e-224 619.0 COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria,4CZ70@85004|Bifidobacteriales 201174|Actinobacteria S Displays ATPase and GTPase activities yvcJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 JIJKFJGP_00904 552531.BIF_00474 1.28e-225 621.0 COG0169@1|root,COG0169@2|Bacteria,2GPQQ@201174|Actinobacteria,4CZCM@85004|Bifidobacteriales 201174|Actinobacteria E Shikimate dehydrogenase substrate binding domain aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv2552c Shikimate_DH,Shikimate_dh_N JIJKFJGP_00905 552531.BIF_00475 0.0 1560.0 COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,4CYVX@85004|Bifidobacteriales 201174|Actinobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N JIJKFJGP_00906 552531.BIF_00976 0.0 2036.0 COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4CYRU@85004|Bifidobacteriales 201174|Actinobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090 - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran JIJKFJGP_00908 552531.BIF_00978 2.31e-230 634.0 COG1030@1|root,COG1030@2|Bacteria,2IG2C@201174|Actinobacteria,4D0UA@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - TspO_MBR JIJKFJGP_00909 552531.BIF_02075 1.57e-127 364.0 COG3663@1|root,COG3663@2|Bacteria,2IGMS@201174|Actinobacteria,4D0QQ@85004|Bifidobacteriales 201174|Actinobacteria L Uracil DNA glycosylase superfamily nnrE - - - - - - - - - - - UDG,YjeF_N JIJKFJGP_00910 552531.BIF_00980 1.93e-157 440.0 COG0400@1|root,COG0400@2|Bacteria,2GNIF@201174|Actinobacteria,4D0TH@85004|Bifidobacteriales 201174|Actinobacteria S Phospholipase/Carboxylesterase - - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2 JIJKFJGP_00911 552531.BIF_00145 0.0 1030.0 COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria,4CYS2@85004|Bifidobacteriales 201174|Actinobacteria S ABC transporter ybiT - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_Xtn,DLIC JIJKFJGP_00912 552531.BIF_01900 3.78e-249 684.0 COG0053@1|root,COG0053@2|Bacteria,2GKSG@201174|Actinobacteria,4D05T@85004|Bifidobacteriales 201174|Actinobacteria P Cation efflux family - - - - - - - - - - - - Cation_efflux,ZT_dimer JIJKFJGP_00913 552531.BIF_00416 3.09e-187 521.0 COG0599@1|root,COG0599@2|Bacteria,2GITB@201174|Actinobacteria,4CZBK@85004|Bifidobacteriales 201174|Actinobacteria S Carboxymuconolactone decarboxylase family - - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD JIJKFJGP_00914 552531.BIF_00207 2.09e-236 649.0 COG3049@1|root,COG3049@2|Bacteria,2GK9Z@201174|Actinobacteria,4CZNU@85004|Bifidobacteriales 201174|Actinobacteria M Linear amide C-N hydrolase, choloylglycine hydrolase family protein cbh - 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 - R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 - - - CBAH JIJKFJGP_00915 552531.BIF_00498 0.0 1162.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2GJHB@201174|Actinobacteria,4CZC5@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N JIJKFJGP_00916 552531.BIF_00497 5e-140 394.0 COG0450@1|root,COG0450@2|Bacteria,2GM74@201174|Actinobacteria,4CZXS@85004|Bifidobacteriales 201174|Actinobacteria O C-terminal domain of 1-Cys peroxiredoxin ahpC - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA JIJKFJGP_00917 552531.BIF_00641 0.0 1167.0 COG0492@1|root,COG3634@1|root,COG0492@2|Bacteria,COG3634@2|Bacteria,2GKD2@201174|Actinobacteria,4CZ6G@85004|Bifidobacteriales 201174|Actinobacteria C Thioredoxin domain - - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Thioredoxin_3 JIJKFJGP_00918 552531.BIF_00467 0.0 1234.0 COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4CZ1T@85004|Bifidobacteriales 201174|Actinobacteria H Belongs to the IlvD Edd family ilvD - 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD JIJKFJGP_00919 552531.BIF_01204 4.74e-60 186.0 COG1758@1|root,COG1758@2|Bacteria,2IQHU@201174|Actinobacteria,4D12C@85004|Bifidobacteriales 201174|Actinobacteria K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 JIJKFJGP_00920 552531.BIF_01203 8.72e-279 764.0 COG0192@1|root,COG0192@2|Bacteria,2GJ4U@201174|Actinobacteria,4CZ5D@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016765,GO:0019899,GO:0030312,GO:0035375,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N JIJKFJGP_00921 552531.BIF_01202 0.0 879.0 COG2230@1|root,COG2230@2|Bacteria,2GJ94@201174|Actinobacteria,4D016@85004|Bifidobacteriales 201174|Actinobacteria M Mycolic acid cyclopropane synthetase cfa GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS JIJKFJGP_00922 552531.BIF_01283 0.0 1455.0 COG1198@1|root,COG1198@2|Bacteria,2GKES@201174|Actinobacteria,4D04J@85004|Bifidobacteriales 201174|Actinobacteria L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - - JIJKFJGP_00923 552531.BIF_01284 1.06e-235 647.0 COG0223@1|root,COG0223@2|Bacteria,2GKH5@201174|Actinobacteria,4CZ8C@85004|Bifidobacteriales 201174|Actinobacteria J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N JIJKFJGP_00924 35760.BCHO_0445 8.15e-110 322.0 COG0560@1|root,COG0560@2|Bacteria,2GJDH@201174|Actinobacteria,4CYWC@85004|Bifidobacteriales 201174|Actinobacteria E haloacid dehalogenase-like hydrolase serB - 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 - - - HAD JIJKFJGP_00925 552531.BIF_02243 5.9e-163 461.0 COG0586@1|root,COG0586@2|Bacteria,2GN43@201174|Actinobacteria,4CZZA@85004|Bifidobacteriales 201174|Actinobacteria S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc JIJKFJGP_00926 552531.BIF_01286 0.0 1007.0 COG1222@1|root,COG1222@2|Bacteria,2GMR1@201174|Actinobacteria,4CZ86@85004|Bifidobacteriales 201174|Actinobacteria O AAA ATPase forming ring-shaped complexes arc GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - ko:K13527 ko03050,map03050 M00342 - - ko00000,ko00001,ko00002,ko03051 - - - AAA,Prot_ATP_ID_OB JIJKFJGP_00927 552531.BIF_00519 0.0 1070.0 COG4122@1|root,COG4122@2|Bacteria,2GJGI@201174|Actinobacteria,4CZAN@85004|Bifidobacteriales 201174|Actinobacteria S Pup-ligase protein dop GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 ko:K20814 - - - - ko00000,ko01000,ko03051 - - - Pup_ligase JIJKFJGP_00928 552531.BIF_01342 4.64e-220 607.0 COG0483@1|root,COG0483@2|Bacteria,2HGP2@201174|Actinobacteria,4CYWZ@85004|Bifidobacteriales 201174|Actinobacteria G Inositol monophosphatase family - - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P JIJKFJGP_00929 552531.BIF_01343 8.24e-41 135.0 2B5FT@1|root,31YAF@2|Bacteria,2GV5R@201174|Actinobacteria,4D1NH@85004|Bifidobacteriales 201174|Actinobacteria S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation pup - - ko:K13570 - - - - ko00000,ko04121 - - - Pup JIJKFJGP_00930 552531.BIF_01344 0.0 998.0 COG0638@1|root,COG0638@2|Bacteria,2GMC6@201174|Actinobacteria,4CZ12@85004|Bifidobacteriales 201174|Actinobacteria O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine pafA GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 ko:K13571 - M00342 R11207 RC00090,RC00096 ko00000,ko00002,ko01000,ko03051 - - - Pup_ligase JIJKFJGP_00931 552531.BIF_01345 4.7e-57 177.0 COG0776@1|root,COG0776@2|Bacteria,2IKQR@201174|Actinobacteria,4D11V@85004|Bifidobacteriales 201174|Actinobacteria L Belongs to the bacterial histone-like protein family hup GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding JIJKFJGP_00932 552531.BIF_01346 0.0 1590.0 COG0392@1|root,COG0392@2|Bacteria,2GMAV@201174|Actinobacteria,4CYRT@85004|Bifidobacteriales 201174|Actinobacteria S Lysylphosphatidylglycerol synthase TM region - - - - - - - - - - - - LPG_synthase_TM JIJKFJGP_00933 552531.BIF_00886 0.0 968.0 COG0015@1|root,COG0015@2|Bacteria,2GM71@201174|Actinobacteria,4CYV6@85004|Bifidobacteriales 201174|Actinobacteria F Adenylosuccinate lyase C-terminal purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ASL_C,Lyase_1 JIJKFJGP_00934 552531.BIF_00802 0.0 1010.0 COG1075@1|root,COG1075@2|Bacteria,2IHFB@201174|Actinobacteria,4CZ17@85004|Bifidobacteriales 201174|Actinobacteria S PGAP1-like protein - - - - - - - - - - - - Abhydrolase_6,Abhydrolase_8,PGAP1 JIJKFJGP_00936 552531.BIF_00804 1.09e-125 360.0 2BG6D@1|root,32A37@2|Bacteria,2IR67@201174|Actinobacteria,4D18W@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00937 552531.BIF_00731 1.23e-230 637.0 COG2304@1|root,COG2304@2|Bacteria,2GJMP@201174|Actinobacteria,4CZ8P@85004|Bifidobacteriales 201174|Actinobacteria S von Willebrand factor (vWF) type A domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA,VWA_2 JIJKFJGP_00938 552531.BIF_00732 1.13e-249 686.0 COG2304@1|root,COG2304@2|Bacteria,2I9VM@201174|Actinobacteria,4CZ00@85004|Bifidobacteriales 201174|Actinobacteria S von Willebrand factor (vWF) type A domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA,VWA_2 JIJKFJGP_00939 552531.BIF_01927 9.9e-116 332.0 2AUTC@1|root,31KGE@2|Bacteria,2IKRN@201174|Actinobacteria,4D134@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00940 552531.BIF_01166 1.98e-231 637.0 COG1721@1|root,COG1721@2|Bacteria,2GKSJ@201174|Actinobacteria,4CYYD@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 JIJKFJGP_00941 552531.BIF_01165 1.79e-246 677.0 COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4CZ2I@85004|Bifidobacteriales 201174|Actinobacteria S ATPase family associated with various cellular activities (AAA) moxR - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 JIJKFJGP_00942 552531.BIF_01164 1.57e-180 501.0 COG0692@1|root,COG0692@2|Bacteria,2GJ9Z@201174|Actinobacteria,4CZ3Y@85004|Bifidobacteriales 201174|Actinobacteria L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG JIJKFJGP_00943 552531.BIF_01163 9.65e-114 333.0 2DP6P@1|root,330SA@2|Bacteria,2GQYA@201174|Actinobacteria,4CZYT@85004|Bifidobacteriales 201174|Actinobacteria S LytR cell envelope-related transcriptional attenuator - - - - - - - - - - - - LytR_C JIJKFJGP_00944 552531.BIF_01928 4.22e-45 145.0 COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4D1FB@85004|Bifidobacteriales 201174|Actinobacteria K 'Cold-shock' DNA-binding domain cspA - - ko:K03704 - - - - ko00000,ko03000 - - - CSD JIJKFJGP_00945 552531.BIF_00400 0.0 1010.0 COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4CZJK@85004|Bifidobacteriales 201174|Actinobacteria O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016020,GO:0016465,GO:0022610,GO:0030112,GO:0030312,GO:0030313,GO:0031975,GO:0032991,GO:0036293,GO:0040007,GO:0042026,GO:0042603,GO:0043388,GO:0044093,GO:0044183,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051704,GO:0061077,GO:0065007,GO:0065009,GO:0070482,GO:0071944,GO:0101031,GO:1990220,GO:2000677,GO:2000679 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 JIJKFJGP_00946 552531.BIF_01558 0.0 1043.0 COG5520@1|root,COG5520@2|Bacteria,2GMWN@201174|Actinobacteria,4CYYZ@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 30 TIM-barrel domain - - 3.2.1.45 ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 - R01498 RC00059,RC00451 ko00000,ko00001,ko01000 - GH30 - CBM_6,FIVAR,Glyco_hydro_30,Glyco_hydro_30C JIJKFJGP_00947 552531.BIF_01474 0.0 1453.0 COG1874@1|root,COG1874@2|Bacteria,2GK4P@201174|Actinobacteria,4CZKE@85004|Bifidobacteriales 201174|Actinobacteria G Beta-galactosidase trimerisation domain - - 3.2.1.23 ko:K12308 ko00052,map00052 - R01105 RC00452 ko00000,ko00001,ko01000 - - - Glyco_hydro_42,Glyco_hydro_42M JIJKFJGP_00948 552531.BIF_01473 7.41e-289 791.0 COG2271@1|root,COG2271@2|Bacteria,2I2GW@201174|Actinobacteria,4D2V8@85004|Bifidobacteriales 201174|Actinobacteria G MFS/sugar transport protein - - - - - - - - - - - - MFS_1 JIJKFJGP_00949 552531.BIF_01472 9.15e-158 441.0 COG1309@1|root,COG1309@2|Bacteria,2ICYK@201174|Actinobacteria,4CYZC@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N JIJKFJGP_00950 552531.BIF_01657 1.87e-111 320.0 COG0783@1|root,COG0783@2|Bacteria,2IFDP@201174|Actinobacteria,4CZV3@85004|Bifidobacteriales 201174|Actinobacteria P Belongs to the Dps family dps - - ko:K04047 - - - - ko00000,ko03036 - - - Ferritin JIJKFJGP_00951 552531.BIF_01656 4.68e-314 857.0 COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4CZKA@85004|Bifidobacteriales 201174|Actinobacteria P Transporter associated domain - - - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 JIJKFJGP_00952 552531.BIF_01655 3.01e-165 462.0 COG0288@1|root,COG0288@2|Bacteria,2GT5H@201174|Actinobacteria,4D06V@85004|Bifidobacteriales 201174|Actinobacteria P Reversible hydration of carbon dioxide cah - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA JIJKFJGP_00953 552531.BIF_01654 7.3e-275 751.0 COG1609@1|root,COG1609@2|Bacteria,2GK1X@201174|Actinobacteria,4CYR6@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - - - - - - - - - - LacI,Peripla_BP_3 JIJKFJGP_00954 552531.BIF_01653 1.3e-48 154.0 2B0EM@1|root,31SS1@2|Bacteria,2GR47@201174|Actinobacteria,4D1E7@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00955 552531.BIF_01652 3.58e-213 589.0 COG1129@1|root,COG1129@2|Bacteria,2GJDV@201174|Actinobacteria,4CZ8T@85004|Bifidobacteriales 201174|Actinobacteria G ATPases associated with a variety of cellular activities - - 3.6.3.17 ko:K02056,ko:K10545 ko02010,map02010 M00215,M00221 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2,3.A.1.2.4 - - ABC_tran JIJKFJGP_00956 552531.BIF_01651 1.59e-71 215.0 2B5E2@1|root,31Y8I@2|Bacteria,2GQWF@201174|Actinobacteria,4D1G4@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00957 552531.BIF_01650 2.57e-250 686.0 COG1609@1|root,COG1609@2|Bacteria,2GJ5Q@201174|Actinobacteria,4D040@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - - - - - - - - - - LacI,Peripla_BP_3 JIJKFJGP_00958 552531.BIF_01649 0.0 1067.0 COG3534@1|root,COG3534@2|Bacteria,2GMAK@201174|Actinobacteria,4CYXS@85004|Bifidobacteriales 201174|Actinobacteria G arabinose metabolic process - - 3.2.1.55 ko:K01209 ko00520,map00520 - R01762 - ko00000,ko00001,ko01000 - GH51 - Alpha-L-AF_C JIJKFJGP_00959 552531.BIF_01648 0.0 1076.0 COG1070@1|root,COG1070@2|Bacteria,2GVSJ@201174|Actinobacteria,4CZK7@85004|Bifidobacteriales 201174|Actinobacteria G FGGY family of carbohydrate kinases, C-terminal domain araB - - - - - - - - - - - FGGY_C,FGGY_N JIJKFJGP_00960 552531.BIF_01647 1.14e-166 467.0 COG0235@1|root,COG0235@2|Bacteria,2GNI6@201174|Actinobacteria,4CZXX@85004|Bifidobacteriales 201174|Actinobacteria G Class II Aldolase and Adducin N-terminal domain araD - 5.1.3.4 ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 M00550 R05850 RC01479 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II JIJKFJGP_00961 552531.BIF_01646 0.0 1028.0 COG2160@1|root,COG2160@2|Bacteria,2GJNB@201174|Actinobacteria,4CZH6@85004|Bifidobacteriales 201174|Actinobacteria G Catalyzes the conversion of L-arabinose to L-ribulose araA - 5.3.1.4 ko:K01804 ko00040,ko01100,map00040,map01100 - R01761 RC00516 ko00000,ko00001,ko01000 - - - Arabinose_Iso_C,Arabinose_Isome JIJKFJGP_00962 552531.BIF_01298 4.08e-216 595.0 COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,4CYUN@85004|Bifidobacteriales 201174|Actinobacteria S Oxidoreductase, aldo keto reductase family protein - - - - - - - - - - - - Aldo_ket_red JIJKFJGP_00963 552531.BIF_01297 0.0 1820.0 COG2352@1|root,COG2352@2|Bacteria,2GKDB@201174|Actinobacteria,4CZS0@85004|Bifidobacteriales 201174|Actinobacteria H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase JIJKFJGP_00964 552531.BIF_01010 0.0 1092.0 COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,2HZ8C@201174|Actinobacteria,4CYR2@85004|Bifidobacteriales 201174|Actinobacteria S Threonine/Serine exporter, ThrE - - - - - - - - - - - - ThrE,ThrE_2 JIJKFJGP_00965 552531.BIF_00830 8.6e-293 800.0 COG1940@1|root,COG1940@2|Bacteria,2GJIE@201174|Actinobacteria,4CZPD@85004|Bifidobacteriales 201174|Actinobacteria GK ROK family xylR - - - - - - - - - - - HTH_IclR,MarR_2,ROK JIJKFJGP_00966 552531.BIF_00829 0.0 1006.0 COG1070@1|root,COG1070@2|Bacteria,2GJDZ@201174|Actinobacteria,4CZH0@85004|Bifidobacteriales 201174|Actinobacteria G FGGY family of carbohydrate kinases, C-terminal domain xylB - 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N JIJKFJGP_00967 552531.BIF_00633 0.0 1111.0 COG3507@1|root,COG3507@2|Bacteria,2GIW3@201174|Actinobacteria,4D08K@85004|Bifidobacteriales 201174|Actinobacteria G candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein K01238 - - - - - - - - - - - - Glyco_hydro_43 JIJKFJGP_00968 552531.BIF_01170 3.21e-299 817.0 COG2272@1|root,COG2272@2|Bacteria,2GJCN@201174|Actinobacteria,4D02Y@85004|Bifidobacteriales 201174|Actinobacteria I Belongs to the type-B carboxylesterase lipase family - - - ko:K03929 - - - - ko00000,ko01000 - CE10 - COesterase JIJKFJGP_00969 552531.BIF_01171 0.0 1356.0 COG3250@1|root,COG3250@2|Bacteria,2ICNG@201174|Actinobacteria,4CZQA@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 2, sugar binding domain protein - - 3.1.1.53 ko:K05970 - - - - ko00000,ko01000 - - - SASA JIJKFJGP_00970 552531.BIF_00092 0.0 1160.0 COG3507@1|root,COG3507@2|Bacteria,2GIW3@201174|Actinobacteria,4CZ5I@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 43 family - - 3.2.1.37 ko:K01198 ko00520,ko01100,map00520,map01100 - R01433 RC00467 ko00000,ko00001,ko01000 - GH43 - Glyco_hydro_43 JIJKFJGP_00971 552531.BIF_00258 1.07e-203 564.0 COG0395@1|root,COG0395@2|Bacteria,2GNQW@201174|Actinobacteria,4CZTW@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02026,ko:K10119,ko:K17243 ko02010,map02010 M00196,M00207,M00600 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.28,3.A.1.1.39 - - BPD_transp_1 JIJKFJGP_00972 552531.BIF_00257 1.54e-246 677.0 COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4CZQU@85004|Bifidobacteriales 201174|Actinobacteria U Binding-protein-dependent transport system inner membrane component - - - ko:K02025,ko:K10118 ko02010,map02010 M00196,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.28 - - BPD_transp_1 JIJKFJGP_00973 552531.BIF_00212 1.02e-310 847.0 COG1653@1|root,COG1653@2|Bacteria,2GP9H@201174|Actinobacteria,4D01H@85004|Bifidobacteriales 201174|Actinobacteria G ABC transporter periplasmic binding protein YcjN precursor K02027 - - - ko:K02027,ko:K10117 ko02010,map02010 M00196,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.28 - - SBP_bac_1,SBP_bac_8 JIJKFJGP_00974 552531.BIF_00432 2.63e-241 667.0 COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria,4CZI0@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory proteins, lacI family - - - ko:K02529,ko:K17640 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 JIJKFJGP_00975 552531.BIF_00405 0.0 1172.0 COG3507@1|root,COG3507@2|Bacteria,2GIW3@201174|Actinobacteria,4CZY8@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 43 family - - 3.2.1.37,3.2.1.55 ko:K01198,ko:K01209 ko00520,ko01100,map00520,map01100 - R01433,R01762 RC00467 ko00000,ko00001,ko01000 - GH43,GH51 - Glyco_hydro_43 JIJKFJGP_00976 552531.BIF_00501 0.0 939.0 COG2115@1|root,COG2115@2|Bacteria,2GJCA@201174|Actinobacteria,4CZK8@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the xylose isomerase family xylA - 5.3.1.5 ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 - R00878,R01432 RC00376,RC00516 ko00000,ko00001,ko01000 - - - AP_endonuc_2 JIJKFJGP_00977 552531.BIF_00127 2.71e-20 82.8 COG0254@1|root,COG0254@2|Bacteria,2IQ4I@201174|Actinobacteria,4D17F@85004|Bifidobacteriales 201174|Actinobacteria J Binds the 23S rRNA rpmE GO:0008150,GO:0040007 - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 JIJKFJGP_00978 552531.BIF_01300 4.17e-236 649.0 COG0083@1|root,COG0083@2|Bacteria,2GKIW@201174|Actinobacteria,4CZN0@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N JIJKFJGP_00979 552531.BIF_01299 1.26e-311 850.0 COG0460@1|root,COG0460@2|Bacteria,2GIX9@201174|Actinobacteria,4CZVD@85004|Bifidobacteriales 201174|Actinobacteria E Homoserine dehydrogenase hom GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.3,2.7.2.4 ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1294 ACT,Homoserine_dh,NAD_binding_3 JIJKFJGP_00980 552531.BIF_02022 0.0 1038.0 COG0019@1|root,COG0019@2|Bacteria,2GKAI@201174|Actinobacteria,4CYRG@85004|Bifidobacteriales 201174|Actinobacteria E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC JIJKFJGP_00981 552531.BIF_01486 0.0 1180.0 COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,4CZ9J@85004|Bifidobacteriales 201174|Actinobacteria J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d JIJKFJGP_00982 552531.BIF_01487 0.0 995.0 COG5520@1|root,COG5520@2|Bacteria,2GMWN@201174|Actinobacteria,4CYYZ@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 30 TIM-barrel domain - - 3.2.1.45 ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 - R01498 RC00059,RC00451 ko00000,ko00001,ko01000 - GH30 - F5_F8_type_C,Glyco_hydro_30,Glyco_hydro_30C,TIG JIJKFJGP_00983 552531.BIF_01488 1.23e-86 256.0 COG0251@1|root,COG0251@2|Bacteria,2IFCR@201174|Actinobacteria,4D0QD@85004|Bifidobacteriales 201174|Actinobacteria J Endoribonuclease L-PSP psp1 - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP JIJKFJGP_00984 552531.BIF_02021 9.46e-144 406.0 COG0395@1|root,COG0395@2|Bacteria,2GK1V@201174|Actinobacteria,4CZF7@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02026,ko:K10242 ko02010,map02010 M00206,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.23 - - BPD_transp_1 JIJKFJGP_00985 552531.BIF_01489 2.42e-235 647.0 COG3459@1|root,COG3459@2|Bacteria,2IAZ0@201174|Actinobacteria,4CZPI@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase 36 superfamily, catalytic domain - - 2.4.1.20 ko:K00702 ko00500,ko01100,map00500,map01100 - R00952 RC00049 ko00000,ko00001,ko01000 - GT36 - Glyco_hydro_36,Glyco_transf_36 JIJKFJGP_00987 552531.BIF_01172 1.96e-219 607.0 COG3118@1|root,COG3118@2|Bacteria,2GJ7B@201174|Actinobacteria,4CZHU@85004|Bifidobacteriales 201174|Actinobacteria O Tetratricopeptide repeat ybbN GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - ko:K05838 - - - - ko00000,ko03110 - - - TPR_19,TPR_20,Thioredoxin JIJKFJGP_00988 552531.BIF_01173 6.91e-235 647.0 28PR0@1|root,2ZCCY@2|Bacteria,2GNNZ@201174|Actinobacteria,4CYX7@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00989 552531.BIF_01174 9.9e-276 759.0 2DMQ0@1|root,32SYI@2|Bacteria,2IA0N@201174|Actinobacteria,4CYQ0@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_00990 552531.BIF_00973 2.58e-223 617.0 COG0545@1|root,COG0545@2|Bacteria,2GJK2@201174|Actinobacteria,4CZEF@85004|Bifidobacteriales 201174|Actinobacteria M FKBP-type peptidyl-prolyl cis-trans isomerase - - 5.2.1.8 ko:K01802 - - - - ko00000,ko01000 - - - FKBP_C JIJKFJGP_00991 552531.BIF_00055 4.85e-180 501.0 COG1637@1|root,COG1637@2|Bacteria,2GIYB@201174|Actinobacteria,4CYXA@85004|Bifidobacteriales 201174|Actinobacteria L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures nucS - - ko:K07503 - - - - ko00000,ko01000 - - - NucS JIJKFJGP_00992 552531.BIF_00683 1.73e-308 883.0 COG1201@1|root,COG1201@2|Bacteria,2GJG3@201174|Actinobacteria,4D01F@85004|Bifidobacteriales 201174|Actinobacteria L DEAD DEAH box helicase lhr - - ko:K03724 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_assoc,HTH_42,Helicase_C JIJKFJGP_00993 552531.BIF_00684 4.77e-220 608.0 COG4975@1|root,COG4975@2|Bacteria,2IBUA@201174|Actinobacteria,4CZIZ@85004|Bifidobacteriales 201174|Actinobacteria G Sugar transport protein - - - ko:K05340 - - - - ko00000,ko02000 2.A.7.5 - - Sugar_transport JIJKFJGP_00994 552531.BIF_00866 0.0 1625.0 COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,4CYVH@85004|Bifidobacteriales 201174|Actinobacteria L DNA topoisomerase (ATP-hydrolyzing) gyrA2 - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV JIJKFJGP_00995 552531.BIF_00750 9.9e-274 750.0 COG1524@1|root,COG1524@2|Bacteria,2GISU@201174|Actinobacteria,4CZCK@85004|Bifidobacteriales 201174|Actinobacteria S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest JIJKFJGP_00996 552531.BIF_00749 3.68e-312 851.0 29W72@1|root,30HS9@2|Bacteria,2HZB4@201174|Actinobacteria,4CZFJ@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3071) - - - - - - - - - - - - DUF3071 JIJKFJGP_00997 552531.BIF_00748 1.42e-62 191.0 2ATJW@1|root,3361K@2|Bacteria,2I80Y@201174|Actinobacteria,4D10Y@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4193) - - - - - - - - - - - - DUF4193 JIJKFJGP_00998 552531.BIF_01790 4.9e-108 311.0 COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4CZUJ@85004|Bifidobacteriales 201174|Actinobacteria F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase JIJKFJGP_00999 552531.BIF_01789 0.0 1464.0 COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4CZCW@85004|Bifidobacteriales 201174|Actinobacteria KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.6.5,3.1.7.2 ko:K00951,ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS JIJKFJGP_01000 552531.BIF_00244 2.43e-284 778.0 COG0448@1|root,COG0448@2|Bacteria,2I2EF@201174|Actinobacteria,4CZ4E@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase JIJKFJGP_01001 552531.BIF_00584 9.8e-171 475.0 COG3677@1|root,COG3677@2|Bacteria,2IEJD@201174|Actinobacteria,4CZ5C@85004|Bifidobacteriales 201174|Actinobacteria L Transposase and inactivated derivatives tnp3503b - - - - - - - - - - - Transposase_mut JIJKFJGP_01002 552531.BIF_00583 2.75e-211 583.0 COG0566@1|root,COG0566@2|Bacteria,2GJ12@201174|Actinobacteria,4CYQ6@85004|Bifidobacteriales 201174|Actinobacteria J SpoU rRNA Methylase family spoU2 - - - - - - - - - - - SpoU_methylase JIJKFJGP_01004 552531.BIF_00067 7.71e-185 514.0 COG1385@1|root,COG1385@2|Bacteria,2GTKX@201174|Actinobacteria,4CZAD@85004|Bifidobacteriales 201174|Actinobacteria J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA JIJKFJGP_01005 552531.BIF_01810 2.19e-77 230.0 COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria,4D130@85004|Bifidobacteriales 201174|Actinobacteria FG Scavenger mRNA decapping enzyme C-term binding hit - - ko:K02503 - - - - ko00000,ko04147 - - - DcpS_C,HIT JIJKFJGP_01006 552531.BIF_01809 1.28e-274 751.0 COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,4CZJH@85004|Bifidobacteriales 201174|Actinobacteria T PhoH-like protein phoH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K06217 - - - - ko00000 - - - PhoH JIJKFJGP_01007 552531.BIF_00389 1.5e-134 380.0 COG0319@1|root,COG0319@2|Bacteria,2GMUF@201174|Actinobacteria,4CZJF@85004|Bifidobacteriales 201174|Actinobacteria S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 JIJKFJGP_01008 552531.BIF_02252 0.0 870.0 COG1253@1|root,COG1253@2|Bacteria,2GIWR@201174|Actinobacteria,4CZ1W@85004|Bifidobacteriales 201174|Actinobacteria S CBS domain corC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - CBS,CorC_HlyC,DUF21 JIJKFJGP_01009 552531.BIF_00129 6.02e-232 640.0 COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria,4CYZH@85004|Bifidobacteriales 201174|Actinobacteria S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 JIJKFJGP_01010 552531.BIF_00162 1.9e-82 262.0 COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4CYYJ@85004|Bifidobacteriales 201174|Actinobacteria I AMP-binding enzyme fadD2 - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding JIJKFJGP_01011 552531.BIF_01743 2.17e-204 563.0 COG3001@1|root,COG3001@2|Bacteria,2GW7W@201174|Actinobacteria,4CZ4W@85004|Bifidobacteriales 201174|Actinobacteria G Fructosamine kinase - - - - - - - - - - - - Fructosamin_kin JIJKFJGP_01012 552531.BIF_01744 1.67e-191 533.0 COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria,4CZ83@85004|Bifidobacteriales 201174|Actinobacteria V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA JIJKFJGP_01013 552531.BIF_00337 4.49e-199 552.0 COG1938@1|root,COG1938@2|Bacteria,2GK10@201174|Actinobacteria,4CYSJ@85004|Bifidobacteriales 201174|Actinobacteria S PAC2 family - - - - - - - - - - - - PAC2 JIJKFJGP_01019 552531.BIF_02016 2.65e-32 112.0 2B3KJ@1|root,31W9X@2|Bacteria,2GWXF@201174|Actinobacteria,4D1NA@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01020 552531.BIF_00376 5.2e-123 352.0 COG0454@1|root,COG0456@2|Bacteria,2IMS5@201174|Actinobacteria,4D0BT@85004|Bifidobacteriales 201174|Actinobacteria K Acetyltransferase (GNAT) domain - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464,GO:0048583,GO:0050789,GO:0065007,GO:0080134,GO:1902882 2.3.1.57 ko:K22441 - - - - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_10 JIJKFJGP_01022 552531.BIF_01771 3.74e-127 362.0 COG0488@1|root,COG0488@2|Bacteria,2GKZC@201174|Actinobacteria,4CZ9C@85004|Bifidobacteriales 201174|Actinobacteria S ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran JIJKFJGP_01023 552531.BIF_00522 0.0 1392.0 COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,4CZD3@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_SAD JIJKFJGP_01024 552531.BIF_01830 8.83e-151 425.0 COG0558@1|root,COG0558@2|Bacteria,2GYKW@201174|Actinobacteria,4D0NB@85004|Bifidobacteriales 201174|Actinobacteria I CDP-alcohol phosphatidyltransferase pgsA1 GO:0003674,GO:0003824,GO:0003881,GO:0003882,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.11,2.7.8.5 ko:K00995,ko:K00999 ko00562,ko00564,ko01100,ko04070,map00562,map00564,map01100,map04070 - R01801,R01802 RC00002,RC00017,RC00078,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf JIJKFJGP_01025 552531.BIF_00294 4.4e-247 677.0 COG1560@1|root,COG1560@2|Bacteria,2GM7B@201174|Actinobacteria,4CYV7@85004|Bifidobacteriales 201174|Actinobacteria M Bacterial lipid A biosynthesis acyltransferase htrB GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.265 ko:K22311 - - - - ko00000,ko01000 - - - Lip_A_acyltrans JIJKFJGP_01026 552531.BIF_01831 1.34e-240 665.0 COG0438@1|root,COG0438@2|Bacteria,2GKQ8@201174|Actinobacteria,4D2RE@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyl transferases group 1 pimA GO:0000026,GO:0000030,GO:0000287,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043169,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046486,GO:0046488,GO:0046872,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.345 ko:K08256 - - R11702 - ko00000,ko01000,ko01003 - GT4 - Glyco_trans_1_4,Glyco_transf_4 JIJKFJGP_01027 552531.BIF_00561 6.09e-175 488.0 COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,4CZ9X@85004|Bifidobacteriales 201174|Actinobacteria K transcriptional regulatory protein yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg JIJKFJGP_01028 552531.BIF_00562 6.75e-132 374.0 COG0817@1|root,COG0817@2|Bacteria,2GJI5@201174|Actinobacteria,4CZ79@85004|Bifidobacteriales 201174|Actinobacteria L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC JIJKFJGP_01029 552531.BIF_00563 5.91e-141 399.0 COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria,4CZCE@85004|Bifidobacteriales 201174|Actinobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N JIJKFJGP_01030 552531.BIF_00229 1.2e-260 714.0 COG2255@1|root,COG2255@2|Bacteria,2GJZF@201174|Actinobacteria,4CZGU@85004|Bifidobacteriales 201174|Actinobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N JIJKFJGP_01031 552531.BIF_01832 1.9e-72 221.0 COG1862@1|root,COG1862@2|Bacteria,2IKUJ@201174|Actinobacteria,4D139@85004|Bifidobacteriales 201174|Actinobacteria U Preprotein translocase subunit yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC JIJKFJGP_01032 552531.BIF_01075 2.2e-133 379.0 COG0503@1|root,COG0503@2|Bacteria,2IM7C@201174|Actinobacteria,4CZ9H@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran JIJKFJGP_01033 552531.BIF_01074 5.72e-283 773.0 COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria,4CZCQ@85004|Bifidobacteriales 201174|Actinobacteria F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA JIJKFJGP_01034 552531.BIF_01073 1.85e-212 587.0 COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4CYX1@85004|Bifidobacteriales 201174|Actinobacteria C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA JIJKFJGP_01035 552531.BIF_00507 0.0 877.0 2EKVE@1|root,33EIZ@2|Bacteria,2HZ8H@201174|Actinobacteria,4CYRN@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01036 552531.BIF_00506 0.0 1093.0 COG0138@1|root,COG0138@2|Bacteria,2GJWU@201174|Actinobacteria,4CZ3P@85004|Bifidobacteriales 201174|Actinobacteria F Bifunctional purine biosynthesis protein PurH purH GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS JIJKFJGP_01037 1690.BPSG_0333 5.52e-37 127.0 2AXAE@1|root,31P9H@2|Bacteria,2IQKC@201174|Actinobacteria,4D18B@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - DUF3017 JIJKFJGP_01038 552531.BIF_00659 3.45e-221 612.0 COG0580@1|root,COG0580@2|Bacteria,2HZ9W@201174|Actinobacteria,4CZ5Q@85004|Bifidobacteriales 201174|Actinobacteria U Belongs to the MIP aquaporin (TC 1.A.8) family - - - ko:K06188 - - - - ko00000,ko02000 1.A.8 - - MIP JIJKFJGP_01039 552531.BIF_00660 7.04e-186 516.0 COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria,4CZGG@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the pseudouridine synthase RsuA family rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 ko:K06178,ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 JIJKFJGP_01040 552531.BIF_00627 0.0 1372.0 COG0283@1|root,COG1160@1|root,COG0283@2|Bacteria,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria,4CYSE@85004|Bifidobacteriales 201174|Actinobacteria F GTPase that plays an essential role in the late steps of ribosome biogenesis der GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - ko:K03977 - - - - ko00000,ko03009 - - - Cytidylate_kin,KH_dom-like,MMR_HSR1 JIJKFJGP_01042 552531.BIF_00196 0.0 976.0 COG4284@1|root,COG4284@2|Bacteria,2I2G3@201174|Actinobacteria,4CYTQ@85004|Bifidobacteriales 201174|Actinobacteria G UTP-glucose-1-phosphate uridylyltransferase ugp - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - UDPGP JIJKFJGP_01043 552531.BIF_00397 0.0 1214.0 COG2378@1|root,COG2378@2|Bacteria,2I8M5@201174|Actinobacteria,4CZWF@85004|Bifidobacteriales 201174|Actinobacteria K WYL domain - - - - - - - - - - - - WYL JIJKFJGP_01044 552531.BIF_01921 2.35e-67 204.0 2B5BE@1|root,31Y5K@2|Bacteria,2IQT5@201174|Actinobacteria,4D17A@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01045 552531.BIF_00604 0.0 1685.0 COG4581@1|root,COG4581@2|Bacteria,2GJEX@201174|Actinobacteria,4CZEC@85004|Bifidobacteriales 201174|Actinobacteria L DEAD DEAH box helicase helY GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - ko:K03727 - - - - ko00000,ko01000 - - - DEAD,DSHCT,Helicase_C,rRNA_proc-arch JIJKFJGP_01046 552531.BIF_00603 5.49e-82 242.0 2CNY9@1|root,32SI2@2|Bacteria,2IMK6@201174|Actinobacteria,4D0V5@85004|Bifidobacteriales 201174|Actinobacteria K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters rbpA GO:0001000,GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0043167,GO:0043169,GO:0043175,GO:0045893,GO:0045935,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - - - - - - - - - - RbpA JIJKFJGP_01047 552531.BIF_01920 2.61e-179 498.0 COG0546@1|root,COG0546@2|Bacteria,2HFGX@201174|Actinobacteria,4CYSF@85004|Bifidobacteriales 201174|Actinobacteria S HAD-hyrolase-like nt5e GO:0003674,GO:0003824,GO:0004672,GO:0004713,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0071704,GO:0140096,GO:1901564 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 JIJKFJGP_01048 552531.BIF_00753 5e-88 258.0 COG0239@1|root,COG0239@2|Bacteria,2HZZC@201174|Actinobacteria,4D2D0@85004|Bifidobacteriales 201174|Actinobacteria D Important for reducing fluoride concentration in the cell, thus reducing its toxicity - - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB JIJKFJGP_01049 552531.BIF_00754 3.58e-85 251.0 COG0239@1|root,COG0239@2|Bacteria 2|Bacteria D Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB JIJKFJGP_01050 552531.BIF_00988 5.12e-91 266.0 29TZI@1|root,30F8H@2|Bacteria,2ISJH@201174|Actinobacteria,4D0Z6@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01051 552531.BIF_00987 2.48e-170 476.0 COG0789@1|root,COG0789@2|Bacteria,2GM67@201174|Actinobacteria,4CZ0X@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, mercury resistance merR2 - - - - - - - - - - - MerR_1 JIJKFJGP_01052 552531.BIF_00986 2.66e-97 283.0 COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4D0R3@85004|Bifidobacteriales 201174|Actinobacteria T Inner membrane component of T3SS, cytoplasmic domain garA GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170 - - - - - - - - - - FHA,Yop-YscD_cpl,zinc_ribbon_2 JIJKFJGP_01053 552531.BIF_00985 1.81e-197 548.0 COG3879@1|root,COG3879@2|Bacteria,2GJ3C@201174|Actinobacteria,4CYYH@85004|Bifidobacteriales 201174|Actinobacteria S Bacterial protein of unknown function (DUF881) - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - DUF881 JIJKFJGP_01054 552531.BIF_01919 1.09e-63 195.0 COG3856@1|root,COG3856@2|Bacteria,2IKJW@201174|Actinobacteria,4D12G@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF1290) sbp - - - - - - - - - - - DUF1290 JIJKFJGP_01055 552531.BIF_01275 2.38e-225 622.0 COG3879@1|root,COG3879@2|Bacteria,2GMS5@201174|Actinobacteria,4CZ72@85004|Bifidobacteriales 201174|Actinobacteria S Bacterial protein of unknown function (DUF881) - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - DUF881 JIJKFJGP_01056 552531.BIF_01276 4.93e-141 399.0 COG0558@1|root,COG0558@2|Bacteria,2GM3F@201174|Actinobacteria,4CZGD@85004|Bifidobacteriales 201174|Actinobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA2 GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf JIJKFJGP_01057 552531.BIF_02247 5.79e-201 557.0 COG0040@1|root,COG0040@2|Bacteria,2GNAX@201174|Actinobacteria,4CZ66@85004|Bifidobacteriales 201174|Actinobacteria F ATP phosphoribosyltransferase hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,HisG_C JIJKFJGP_01058 552531.BIF_02246 3.18e-55 172.0 COG0140@1|root,COG0140@2|Bacteria,2IQ4D@201174|Actinobacteria,4D108@85004|Bifidobacteriales 201174|Actinobacteria E Phosphoribosyl-ATP pyrophosphohydrolase hisE GO:0000287,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0044403,GO:0044419,GO:0044464,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0071944,GO:0075136,GO:0075139 3.6.1.31 ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - PRA-PH JIJKFJGP_01059 552531.BIF_01279 2.68e-157 441.0 COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria,4CYX0@85004|Bifidobacteriales 201174|Actinobacteria G Ribulose-phosphate 3-epimerase rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim JIJKFJGP_01060 552531.BIF_01280 4.78e-235 645.0 COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria,4CYV8@85004|Bifidobacteriales 201174|Actinobacteria M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - LGT JIJKFJGP_01061 552531.BIF_00031 3.55e-206 571.0 COG0159@1|root,COG0159@2|Bacteria,2GN6T@201174|Actinobacteria,4D0A3@85004|Bifidobacteriales 201174|Actinobacteria E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA JIJKFJGP_01062 552531.BIF_00318 0.0 1382.0 COG0133@1|root,COG0133@2|Bacteria,2GM7Z@201174|Actinobacteria,4CZJW@85004|Bifidobacteriales 201174|Actinobacteria E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - IGPS,PALP JIJKFJGP_01063 1688.BCUN_0772 0.00074 43.1 2A079@1|root,30NAF@2|Bacteria,2ITFX@201174|Actinobacteria,4D18F@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01064 552531.BIF_01917 3.13e-11 58.9 2B5A6@1|root,31Y4B@2|Bacteria,2H06U@201174|Actinobacteria,4D1U8@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01065 552531.BIF_00559 4.39e-148 416.0 COG1573@1|root,COG1573@2|Bacteria,2IH02@201174|Actinobacteria,4D0XP@85004|Bifidobacteriales 201174|Actinobacteria L Uracil DNA glycosylase superfamily - - - - - - - - - - - - UDG JIJKFJGP_01066 552531.BIF_00560 0.0 1032.0 COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,4CZHW@85004|Bifidobacteriales 201174|Actinobacteria E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind JIJKFJGP_01067 552531.BIF_01259 6.65e-100 289.0 COG0139@1|root,COG0139@2|Bacteria,2IKKU@201174|Actinobacteria,4D0WW@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP hisI GO:0008150,GO:0040007 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1606 PRA-CH JIJKFJGP_01068 552531.BIF_01260 2.11e-178 497.0 COG0107@1|root,COG0107@2|Bacteria,2GIRP@201174|Actinobacteria,4CZ8Z@85004|Bifidobacteriales 201174|Actinobacteria E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007 4.1.3.27 ko:K01657,ko:K02500 ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023,M00026 R00985,R00986,R04558 RC00010,RC01190,RC01943,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth JIJKFJGP_01069 552531.BIF_01261 4.44e-173 483.0 COG1511@1|root,COG1511@2|Bacteria,2HZM3@201174|Actinobacteria,4D0WD@85004|Bifidobacteriales 201174|Actinobacteria S ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane JIJKFJGP_01070 552531.BIF_01262 3.54e-149 420.0 COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4CYUQ@85004|Bifidobacteriales 201174|Actinobacteria V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran JIJKFJGP_01071 552531.BIF_01263 7.65e-136 384.0 COG1309@1|root,COG1309@2|Bacteria,2IQCK@201174|Actinobacteria,4D114@85004|Bifidobacteriales 201174|Actinobacteria K WHG domain - - - - - - - - - - - - TetR_N,WHG JIJKFJGP_01072 552531.BIF_01264 3.81e-294 803.0 COG0820@1|root,COG0820@2|Bacteria,2GJ48@201174|Actinobacteria,4CZG2@85004|Bifidobacteriales 201174|Actinobacteria J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Radical_SAM JIJKFJGP_01073 552531.BIF_02013 5.59e-226 623.0 COG0575@1|root,COG0575@2|Bacteria,2I7ZA@201174|Actinobacteria,4CYZM@85004|Bifidobacteriales 201174|Actinobacteria I Cytidylyltransferase family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 JIJKFJGP_01074 552531.BIF_01916 1.16e-119 343.0 COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria,4CYTF@85004|Bifidobacteriales 201174|Actinobacteria J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF JIJKFJGP_01075 552531.BIF_01915 5.41e-172 480.0 COG0528@1|root,COG0528@2|Bacteria,2GKWQ@201174|Actinobacteria,4CZEK@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the reversible phosphorylation of UMP to UDP pyrH GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase JIJKFJGP_01076 552531.BIF_02111 2.5e-177 499.0 COG0264@1|root,COG0264@2|Bacteria,2GK4M@201174|Actinobacteria,4CYVQ@85004|Bifidobacteriales 201174|Actinobacteria J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS JIJKFJGP_01077 552531.BIF_01742 1.03e-208 578.0 COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,4CZ96@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 JIJKFJGP_01078 552531.BIF_01745 5.55e-111 319.0 COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,4CZ63@85004|Bifidobacteriales 201174|Actinobacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase JIJKFJGP_01079 31954.BPSP_0430 0.0 1013.0 COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4CYVD@85004|Bifidobacteriales 201174|Actinobacteria I long-chain-fatty acid CoA ligase fadD3 - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding JIJKFJGP_01081 552531.BIF_02112 2.97e-266 729.0 COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,4CZDK@85004|Bifidobacteriales 201174|Actinobacteria F IMP dehydrogenase family protein guaB3 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - IMPDH JIJKFJGP_01082 552531.BIF_00445 1.2e-305 833.0 COG0538@1|root,COG0538@2|Bacteria,2GM3D@201174|Actinobacteria,4CZ8V@85004|Bifidobacteriales 201174|Actinobacteria C Belongs to the isocitrate and isopropylmalate dehydrogenases family icd GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh JIJKFJGP_01083 552531.BIF_00836 0.0 963.0 COG4213@1|root,COG4213@2|Bacteria,2HZAK@201174|Actinobacteria,4CZCR@85004|Bifidobacteriales 201174|Actinobacteria G ABC transporter substrate-binding protein - - - - - - - - - - - - Peripla_BP_4 JIJKFJGP_01084 552531.BIF_00835 1.13e-137 390.0 COG0739@1|root,COG0739@2|Bacteria,2IQ64@201174|Actinobacteria,4D199@85004|Bifidobacteriales 201174|Actinobacteria M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 JIJKFJGP_01085 552531.BIF_01854 1.16e-81 242.0 2A3Y6@1|root,30SGI@2|Bacteria,2IM76@201174|Actinobacteria,4D10Z@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01087 552531.BIF_00247 1.79e-117 336.0 2AUE2@1|root,32FQ3@2|Bacteria,2HZQ8@201174|Actinobacteria,4D1IB@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01089 552531.BIF_00246 7.97e-251 688.0 COG0533@1|root,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,4CZ0K@85004|Bifidobacteriales 201174|Actinobacteria O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Acetyltransf_1,Peptidase_M22 JIJKFJGP_01090 552531.BIF_00245 3.49e-118 337.0 COG0454@1|root,COG0456@2|Bacteria,2IM9R@201174|Actinobacteria,4D0Q0@85004|Bifidobacteriales 201174|Actinobacteria K FR47-like protein rimI GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 JIJKFJGP_01091 552531.BIF_00426 7.23e-202 558.0 COG1214@1|root,COG1214@2|Bacteria,2GMTM@201174|Actinobacteria,4D0A2@85004|Bifidobacteriales 201174|Actinobacteria O Glycoprotease family yeaZ GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - ko:K14742 - - - - ko00000,ko03016 - - - Peptidase_M22 JIJKFJGP_01092 552531.BIF_00427 1.84e-146 412.0 COG0802@1|root,COG0802@2|Bacteria,2IKV2@201174|Actinobacteria,4D0PH@85004|Bifidobacteriales 201174|Actinobacteria S Threonylcarbamoyl adenosine biosynthesis protein TsaE tsaE GO:0008150,GO:0040007 - ko:K06925 - - - - ko00000,ko03016 - - - TsaE JIJKFJGP_01093 552531.BIF_00697 2.44e-239 659.0 COG1466@1|root,COG1466@2|Bacteria,2GNMZ@201174|Actinobacteria,4CZ07@85004|Bifidobacteriales 201174|Actinobacteria L DNA polymerase III delta subunit holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta JIJKFJGP_01094 552531.BIF_00696 0.0 1163.0 COG0658@1|root,COG0658@2|Bacteria,2GJGR@201174|Actinobacteria,4CZ6X@85004|Bifidobacteriales 201174|Actinobacteria S Competence protein comEC - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B JIJKFJGP_01095 552531.BIF_00276 2.36e-171 479.0 COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4D176@85004|Bifidobacteriales 201174|Actinobacteria L Helix-hairpin-helix motif comEA - - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3,SLBB JIJKFJGP_01096 552531.BIF_00793 0.0 2053.0 COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,4CZHV@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 JIJKFJGP_01097 552531.BIF_00650 5.23e-213 589.0 COG0834@1|root,COG0834@2|Bacteria,2I9PU@201174|Actinobacteria,4D09U@85004|Bifidobacteriales 201174|Actinobacteria ET Bacterial periplasmic substrate-binding proteins - - - ko:K10005 ko02010,map02010 M00233 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.9 - - SBP_bac_3 JIJKFJGP_01098 552531.BIF_00651 5.76e-217 600.0 COG0598@1|root,COG0598@2|Bacteria,2HZ8V@201174|Actinobacteria,4CYWX@85004|Bifidobacteriales 201174|Actinobacteria P CorA-like Mg2+ transporter protein corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA JIJKFJGP_01099 552531.BIF_00415 1.72e-206 570.0 COG0406@1|root,COG0406@2|Bacteria,2GJYU@201174|Actinobacteria,4CZI8@85004|Bifidobacteriales 201174|Actinobacteria G Phosphoglycerate mutase family gpmB GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237 3.1.3.85,5.4.2.11 ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 JIJKFJGP_01100 552531.BIF_00414 9.97e-94 273.0 COG3576@1|root,COG3576@2|Bacteria,2IJK2@201174|Actinobacteria,4D0W8@85004|Bifidobacteriales 201174|Actinobacteria S Pfam:Pyridox_oxidase pdxH - - ko:K07006 - - - - ko00000 - - - Putative_PNPOx JIJKFJGP_01103 552531.BIF_01797 3.21e-134 390.0 2E39G@1|root,32Y91@2|Bacteria,2IMAD@201174|Actinobacteria,4D0XM@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01104 552531.BIF_01798 6.21e-159 444.0 COG0406@1|root,COG0406@2|Bacteria,2GJYU@201174|Actinobacteria,4CYXK@85004|Bifidobacteriales 201174|Actinobacteria G Phosphoglycerate mutase family gpmB GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237 3.1.3.85,5.4.2.11 ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 JIJKFJGP_01105 552531.BIF_01799 4.35e-94 274.0 COG0799@1|root,COG0799@2|Bacteria,2IKZ3@201174|Actinobacteria,4D11U@85004|Bifidobacteriales 201174|Actinobacteria J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS - - ko:K09710 - - - - ko00000,ko03009 - - - RsfS JIJKFJGP_01106 552531.BIF_00738 0.0 912.0 COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,4CZ4C@85004|Bifidobacteriales 201174|Actinobacteria M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transf_3,NTP_transferase JIJKFJGP_01108 552531.BIF_00739 2.27e-246 676.0 COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4CYRD@85004|Bifidobacteriales 201174|Actinobacteria F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N JIJKFJGP_01109 552531.BIF_00366 1.06e-171 478.0 COG1057@1|root,COG1057@2|Bacteria,2GMFZ@201174|Actinobacteria,4CZ82@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like JIJKFJGP_01110 552531.BIF_00884 3.59e-148 417.0 2A13J@1|root,30P9F@2|Bacteria,2GKGD@201174|Actinobacteria,4D0QR@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01111 552531.BIF_00883 4.6e-307 838.0 COG0014@1|root,COG0014@2|Bacteria,2GISA@201174|Actinobacteria,4CZ2H@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA GO:0003674,GO:0003824,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv2427c Aldedh JIJKFJGP_01112 552531.BIF_00882 0.0 991.0 COG0498@1|root,COG0498@2|Bacteria,2GIRY@201174|Actinobacteria,4CYS0@85004|Bifidobacteriales 201174|Actinobacteria E Threonine synthase N terminus thrC - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_synth_N JIJKFJGP_01113 552531.BIF_00355 3.85e-166 464.0 COG0637@1|root,COG0637@2|Bacteria,2I362@201174|Actinobacteria,4CZ8D@85004|Bifidobacteriales 201174|Actinobacteria S Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 JIJKFJGP_01114 552531.BIF_00725 0.0 1073.0 COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria,4CYYF@85004|Bifidobacteriales 201174|Actinobacteria L May be involved in recombinational repair of damaged DNA recN GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N JIJKFJGP_01115 552531.BIF_00726 8.73e-236 648.0 COG0061@1|root,COG0061@2|Bacteria,2GKM2@201174|Actinobacteria,4CYZ0@85004|Bifidobacteriales 201174|Actinobacteria H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase JIJKFJGP_01116 552531.BIF_00921 9.59e-152 427.0 COG0569@1|root,COG0569@2|Bacteria,2IA09@201174|Actinobacteria,4CZVT@85004|Bifidobacteriales 201174|Actinobacteria P TrkA-N domain trkA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N JIJKFJGP_01117 552531.BIF_00920 0.0 952.0 COG0168@1|root,COG0168@2|Bacteria,2GKKS@201174|Actinobacteria,4CZH7@85004|Bifidobacteriales 201174|Actinobacteria P Cation transport protein trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH JIJKFJGP_01118 552531.BIF_00919 8.69e-185 514.0 COG1189@1|root,COG1189@2|Bacteria,2GJVT@201174|Actinobacteria,4CZSS@85004|Bifidobacteriales 201174|Actinobacteria J Ribosomal RNA large subunit methyltransferase J tlyA GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 ko:K06442 - - - - ko00000,ko01000,ko03009 - - - FtsJ,S4 JIJKFJGP_01119 552531.BIF_00918 4.09e-248 681.0 COG0647@1|root,COG0647@2|Bacteria,2GK7V@201174|Actinobacteria,4CZ1Z@85004|Bifidobacteriales 201174|Actinobacteria G Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - Hydrolase_6,Hydrolase_like JIJKFJGP_01120 552531.BIF_00302 2.75e-261 732.0 COG0457@1|root,COG0457@2|Bacteria,2GKX5@201174|Actinobacteria,4CYXN@85004|Bifidobacteriales 201174|Actinobacteria L Tetratricopeptide repeat - - - - - - - - - - - - TPR_19 JIJKFJGP_01121 552531.BIF_00553 0.0 882.0 COG0162@1|root,COG0162@2|Bacteria,2GJPR@201174|Actinobacteria,4CZKG@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b JIJKFJGP_01122 552531.BIF_00552 3.62e-116 335.0 COG1418@1|root,COG1418@2|Bacteria,2IFXP@201174|Actinobacteria,4D0P2@85004|Bifidobacteriales 201174|Actinobacteria S Metal dependent phosphohydrolases with conserved 'HD' motif. - - - ko:K06950 - - - - ko00000 - - - HD JIJKFJGP_01123 552531.BIF_02081 2.58e-183 511.0 COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4D2RI@85004|Bifidobacteriales 201174|Actinobacteria IQ Enoyl-(Acyl carrier protein) reductase butA - 1.1.1.100,1.1.1.304,1.1.1.76 ko:K00059,ko:K03366 ko00061,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00650,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R02855,R02946,R03707,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R09078,R10116,R10120,R10505,R11671 RC00029,RC00117,RC00205,RC00525 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 JIJKFJGP_01124 552531.BIF_00354 0.0 980.0 COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria,4CZ50@85004|Bifidobacteriales 201174|Actinobacteria E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 JIJKFJGP_01125 552531.BIF_00681 8.47e-304 827.0 COG0137@1|root,COG0137@2|Bacteria,2GK96@201174|Actinobacteria,4CZ2R@85004|Bifidobacteriales 201174|Actinobacteria E Belongs to the argininosuccinate synthase family. Type 1 subfamily argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - iNJ661.Rv1658 Arginosuc_synth JIJKFJGP_01126 552531.BIF_00682 1.23e-119 342.0 COG1438@1|root,COG1438@2|Bacteria,2GKA5@201174|Actinobacteria,4D0VM@85004|Bifidobacteriales 201174|Actinobacteria K Regulates arginine biosynthesis genes argR GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - ko:K03402 - - - - ko00000,ko03000 - - - Arg_repressor,Arg_repressor_C JIJKFJGP_01127 552531.BIF_00861 5.7e-235 645.0 COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,4CZGN@85004|Bifidobacteriales 201174|Actinobacteria E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N JIJKFJGP_01128 552531.BIF_00862 1.31e-305 832.0 COG4992@1|root,COG4992@2|Bacteria,2GKE9@201174|Actinobacteria,4CZGW@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase class-III argD GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 JIJKFJGP_01129 552531.BIF_00809 5.02e-228 628.0 COG0548@1|root,COG0548@2|Bacteria,2GKDS@201174|Actinobacteria,4CYYX@85004|Bifidobacteriales 201174|Actinobacteria E Belongs to the acetylglutamate kinase family. ArgB subfamily argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase JIJKFJGP_01130 552531.BIF_00810 7.16e-278 760.0 COG1364@1|root,COG1364@2|Bacteria,2GIW0@201174|Actinobacteria,4CZQQ@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ JIJKFJGP_01131 552531.BIF_01029 1.64e-260 715.0 COG0002@1|root,COG0002@2|Bacteria,2GKQK@201174|Actinobacteria,4CZNC@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC JIJKFJGP_01132 552531.BIF_01028 5.69e-190 527.0 2AHAX@1|root,317M8@2|Bacteria,2IPJ5@201174|Actinobacteria,4D11M@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01133 552531.BIF_00495 0.0 1754.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2GMFD@201174|Actinobacteria,4CYUM@85004|Bifidobacteriales 201174|Actinobacteria J Phenylalanyl-tRNA synthetase beta pheT GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind JIJKFJGP_01134 552531.BIF_00187 3.65e-251 689.0 COG0016@1|root,COG0016@2|Bacteria,2GJGG@201174|Actinobacteria,4CZ78@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d JIJKFJGP_01135 552531.BIF_00345 9.87e-217 598.0 COG0566@1|root,COG0566@2|Bacteria,2GJI6@201174|Actinobacteria,4CYZQ@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family tsnR - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind JIJKFJGP_01136 35760.BCHO_0781 1.8e-18 85.9 COG0577@1|root,COG0577@2|Bacteria,2GMGJ@201174|Actinobacteria,4CZ0B@85004|Bifidobacteriales 201174|Actinobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD JIJKFJGP_01137 552531.BIF_00153 2.42e-288 792.0 COG0577@1|root,COG0577@2|Bacteria,2GMGJ@201174|Actinobacteria,4CZ0B@85004|Bifidobacteriales 201174|Actinobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD JIJKFJGP_01138 552531.BIF_00152 3.03e-169 473.0 COG1136@1|root,COG1136@2|Bacteria,2I7UV@201174|Actinobacteria,4CZ1C@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter, ATP-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran JIJKFJGP_01139 552531.BIF_00363 0.0 1514.0 COG0619@1|root,COG1122@1|root,COG0619@2|Bacteria,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4CYZ6@85004|Bifidobacteriales 201174|Actinobacteria P ATPases associated with a variety of cellular activities ykoD - - ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran,CbiQ JIJKFJGP_01140 552531.BIF_00822 1.05e-287 790.0 COG1136@1|root,COG1136@2|Bacteria 2|Bacteria V lipoprotein transporter activity ytrE - - ko:K02003,ko:K10038 ko02010,map02010 M00227,M00258 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.3.2 - - ABC_tran,cNMP_binding JIJKFJGP_01141 552531.BIF_00620 6.74e-209 577.0 COG3023@1|root,COG3023@2|Bacteria,2I9EN@201174|Actinobacteria,4D025@85004|Bifidobacteriales 201174|Actinobacteria V N-Acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - - JIJKFJGP_01142 1690.BPSG_0236 1.03e-55 181.0 2F769@1|root,33ZMP@2|Bacteria,2IFMJ@201174|Actinobacteria,4D0UD@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01143 552531.BIF_00011 7.53e-272 744.0 COG4585@1|root,COG4585@2|Bacteria,2II1W@201174|Actinobacteria,4D0V3@85004|Bifidobacteriales 201174|Actinobacteria T Histidine kinase - - - - - - - - - - - - HisKA_3 JIJKFJGP_01144 552531.BIF_00131 0.0 915.0 COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,4CYZT@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase dimerisation domain argE - - - - - - - - - - - M20_dimer,Peptidase_M20 JIJKFJGP_01145 552531.BIF_00130 6.92e-134 380.0 2AN86@1|root,31D67@2|Bacteria,2HWWU@201174|Actinobacteria,4CZZS@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3043) - GO:0008150,GO:0009605,GO:0009607,GO:0020012,GO:0030682,GO:0042783,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 - - - - - - - - - - DUF3043 JIJKFJGP_01146 552531.BIF_01803 0.0 972.0 COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,4CZEI@85004|Bifidobacteriales 201174|Actinobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family lpdA - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim JIJKFJGP_01147 552531.BIF_01802 1.07e-188 524.0 2AUFS@1|root,2ZBYU@2|Bacteria,2I87Z@201174|Actinobacteria,4CYT8@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4191) - - - - - - - - - - - - DUF4191 JIJKFJGP_01148 552531.BIF_00348 0.0 972.0 COG0174@1|root,COG0174@2|Bacteria,2GMN1@201174|Actinobacteria,4CZNK@85004|Bifidobacteriales 201174|Actinobacteria E glutamine synthetase glnA GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N JIJKFJGP_01149 552531.BIF_00880 3.49e-143 404.0 COG4721@1|root,COG4721@2|Bacteria,2IDAN@201174|Actinobacteria,4D00D@85004|Bifidobacteriales 201174|Actinobacteria S ABC-type cobalt transport system, permease component ykoE - - ko:K16925 - M00582 - - ko00000,ko00002,ko02000 3.A.1.30 - - ABC_cobalt JIJKFJGP_01150 552531.BIF_00879 5.3e-263 721.0 COG0489@1|root,COG0489@2|Bacteria,2GJUZ@201174|Actinobacteria,4CZDC@85004|Bifidobacteriales 201174|Actinobacteria D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp GO:0008150,GO:0040007 - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA JIJKFJGP_01151 552531.BIF_00179 0.0 1739.0 COG0272@1|root,COG0272@2|Bacteria,2GJUY@201174|Actinobacteria,4CZBC@85004|Bifidobacteriales 201174|Actinobacteria L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2 JIJKFJGP_01152 552531.BIF_01102 0.0 2174.0 COG0457@1|root,COG0457@2|Bacteria,2GWSR@201174|Actinobacteria,4CZ33@85004|Bifidobacteriales 201174|Actinobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_19 JIJKFJGP_01153 552531.BIF_01103 0.0 1449.0 COG1807@1|root,COG1807@2|Bacteria,2GNXR@201174|Actinobacteria,4CZXK@85004|Bifidobacteriales 201174|Actinobacteria M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - - JIJKFJGP_01154 552531.BIF_00555 7.71e-193 536.0 COG1122@1|root,COG1122@2|Bacteria,2I9PF@201174|Actinobacteria,4D04S@85004|Bifidobacteriales 201174|Actinobacteria P ATPases associated with a variety of cellular activities - - - ko:K16784 ko02010,map02010 M00581 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25.1 - - ABC_tran JIJKFJGP_01155 552531.BIF_00556 1.3e-283 774.0 COG0436@1|root,COG0436@2|Bacteria,2GNMB@201174|Actinobacteria,4CZ48@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase class I and II - - - - - - - - - - - - Aminotran_1_2 JIJKFJGP_01156 35760.BCHO_0814 1.93e-172 482.0 COG1940@1|root,COG1940@2|Bacteria,2GJA0@201174|Actinobacteria,4CYR1@85004|Bifidobacteriales 201174|Actinobacteria GK ROK family ppgK - 2.7.1.2,2.7.1.63 ko:K00845,ko:K00886 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786,R02187,R02189 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK JIJKFJGP_01157 1690.BPSG_0205 2.94e-85 257.0 COG3601@1|root,COG3601@2|Bacteria,2IAX0@201174|Actinobacteria,4CZQD@85004|Bifidobacteriales 201174|Actinobacteria U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins - - - - - - - - - - - - ECF_trnsprt JIJKFJGP_01158 552531.BIF_01117 0.0 1480.0 COG0619@1|root,COG1129@1|root,COG0619@2|Bacteria,COG1129@2|Bacteria,2I2G4@201174|Actinobacteria,4CZJE@85004|Bifidobacteriales 201174|Actinobacteria GP ABC transporter, ATP-binding protein - - - ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran,CbiQ JIJKFJGP_01159 552531.BIF_01116 7.3e-210 578.0 COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,4CZ1F@85004|Bifidobacteriales 201174|Actinobacteria S Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red JIJKFJGP_01160 552531.BIF_01751 1.9e-62 191.0 COG1534@1|root,COG1534@2|Bacteria,2IKSS@201174|Actinobacteria,4D10K@85004|Bifidobacteriales 201174|Actinobacteria J CRS1_YhbY - - - ko:K07574 - - - - ko00000,ko03009 - - - CRS1_YhbY JIJKFJGP_01161 552531.BIF_00231 7.88e-182 506.0 COG0819@1|root,COG0819@2|Bacteria,2IA0S@201174|Actinobacteria,4CZUI@85004|Bifidobacteriales 201174|Actinobacteria K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway tenA - 3.5.99.2 ko:K03707 ko00730,ko01100,map00730,map01100 - R02133,R09993 RC00224,RC00652,RC02832 ko00000,ko00001,ko01000,ko03000 - - - TENA_THI-4 JIJKFJGP_01162 552531.BIF_01752 1.17e-93 274.0 COG3304@1|root,COG3304@2|Bacteria,2IKS5@201174|Actinobacteria,4D11K@85004|Bifidobacteriales 201174|Actinobacteria S Inner membrane component domain yccF - - - - - - - - - - - YccF JIJKFJGP_01163 552531.BIF_00264 1.42e-85 251.0 COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,4D10G@85004|Bifidobacteriales 201174|Actinobacteria S Zincin-like metallopeptidase - - - - - - - - - - - - Zincin_1 JIJKFJGP_01164 552531.BIF_00263 2.23e-184 511.0 COG1246@1|root,COG1246@2|Bacteria,2I61X@201174|Actinobacteria,4D2U1@85004|Bifidobacteriales 201174|Actinobacteria E Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - Acetyltransf_1 JIJKFJGP_01165 552531.BIF_00585 0.0 1058.0 29E27@1|root,30105@2|Bacteria,2IDHW@201174|Actinobacteria,4D034@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01167 552531.BIF_00760 8.63e-255 699.0 COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4D023@85004|Bifidobacteriales 201174|Actinobacteria L Transposase, Mutator family - - - - - - - - - - - - Transposase_mut JIJKFJGP_01168 552531.BIF_00385 0.0 1259.0 COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4CYYC@85004|Bifidobacteriales 201174|Actinobacteria I AMP-binding enzyme - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding JIJKFJGP_01169 552531.BIF_00308 0.0 927.0 COG0477@1|root,COG2814@2|Bacteria,2GIZX@201174|Actinobacteria,4CZ0R@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr JIJKFJGP_01170 552531.BIF_00505 0.0 954.0 COG2256@1|root,COG2256@2|Bacteria,2GKDP@201174|Actinobacteria,4CZ2K@85004|Bifidobacteriales 201174|Actinobacteria L Recombination factor protein RarA rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N JIJKFJGP_01171 552531.BIF_00504 0.0 1707.0 COG4581@1|root,COG4581@2|Bacteria,2GJSV@201174|Actinobacteria,4CZVX@85004|Bifidobacteriales 201174|Actinobacteria L DEAD DEAH box helicase - - - - - - - - - - - - DEAD,DUF3516,Helicase_C JIJKFJGP_01172 552531.BIF_01792 1.25e-239 657.0 COG2326@1|root,COG2326@2|Bacteria,2GKRN@201174|Actinobacteria,4CZZU@85004|Bifidobacteriales 201174|Actinobacteria S Polyphosphate kinase 2 (PPK2) - - - - - - - - - - - - PPK2 JIJKFJGP_01173 552531.BIF_00776 1.1e-256 704.0 COG0765@1|root,COG0765@2|Bacteria,2GNBH@201174|Actinobacteria,4CZB4@85004|Bifidobacteriales 201174|Actinobacteria E Binding-protein-dependent transport system inner membrane component gluD - - ko:K10007 ko02010,map02010 M00233 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.9 - - BPD_transp_1 JIJKFJGP_01174 552531.BIF_00777 2.23e-142 404.0 COG0765@1|root,COG0765@2|Bacteria,2GNUR@201174|Actinobacteria,4CZ5M@85004|Bifidobacteriales 201174|Actinobacteria E Binding-protein-dependent transport system inner membrane component gluC - - ko:K10006 ko02010,map02010 M00233 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.9 - - BPD_transp_1 JIJKFJGP_01175 552531.BIF_00778 1.51e-198 550.0 COG0834@1|root,COG0834@2|Bacteria,2GJH8@201174|Actinobacteria,4CZA4@85004|Bifidobacteriales 201174|Actinobacteria ET Belongs to the bacterial solute-binding protein 3 family gluB - - ko:K10005 ko02010,map02010 M00233 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.9 - - SBP_bac_3 JIJKFJGP_01176 552531.BIF_00779 1.1e-182 508.0 COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4CYXE@85004|Bifidobacteriales 201174|Actinobacteria E ATP-binding protein of ABC transporter for glutamate K02028 gluA - - ko:K10008 ko02010,map02010 M00233 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.9 - - ABC_tran JIJKFJGP_01177 552531.BIF_00780 1.4e-189 526.0 COG1073@1|root,COG1073@2|Bacteria,2HW4C@201174|Actinobacteria,4D04D@85004|Bifidobacteriales 201174|Actinobacteria S Serine aminopeptidase, S33 - - - ko:K06889 - - - - ko00000 - - - Abhydrolase_6,Hydrolase_4 JIJKFJGP_01178 552531.BIF_00028 5.33e-294 809.0 COG3266@1|root,COG3266@2|Bacteria,2I2EC@201174|Actinobacteria,4CYYM@85004|Bifidobacteriales 201174|Actinobacteria S Domain of Unknown Function (DUF349) - - - - - - - - - - - - DUF349 JIJKFJGP_01179 552531.BIF_00016 0.0 894.0 COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,4CYR9@85004|Bifidobacteriales 201174|Actinobacteria J Histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His JIJKFJGP_01180 552531.BIF_02065 0.0 1208.0 COG0173@1|root,COG0173@2|Bacteria,2GJHU@201174|Actinobacteria,4CYWQ@85004|Bifidobacteriales 201174|Actinobacteria J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon JIJKFJGP_01181 552531.BIF_00332 0.0 1588.0 COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4CZCH@85004|Bifidobacteriales 201174|Actinobacteria O ATPase family associated with various cellular activities (AAA) clpC GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944 - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR JIJKFJGP_01182 552531.BIF_00719 1.7e-234 645.0 COG0589@1|root,COG0589@2|Bacteria,2IA7S@201174|Actinobacteria,4CZZ0@85004|Bifidobacteriales 201174|Actinobacteria T Belongs to the universal stress protein A family uspA - - - - - - - - - - - Usp JIJKFJGP_01183 552531.BIF_00718 6.14e-178 503.0 29Z8E@1|root,30M6H@2|Bacteria,2IT29@201174|Actinobacteria,4D184@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01184 552531.BIF_00934 4.88e-266 729.0 28NWB@1|root,2ZBU7@2|Bacteria,2GJ74@201174|Actinobacteria,4CYW9@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3027) - - - - - - - - - - - - DUF3027 JIJKFJGP_01185 552531.BIF_00935 1.15e-103 300.0 COG1278@1|root,COG1278@2|Bacteria,2IKXN@201174|Actinobacteria,4D0V4@85004|Bifidobacteriales 201174|Actinobacteria K 'Cold-shock' DNA-binding domain cspB - - ko:K03704 - - - - ko00000,ko03000 - - - CSD JIJKFJGP_01186 552531.BIF_00936 0.0 1156.0 COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,2I2DU@201174|Actinobacteria,4CZNF@85004|Bifidobacteriales 201174|Actinobacteria T ATPase histidine kinase DNA gyrase B HSP90 domain protein phoR - 2.7.13.3 ko:K02484 - - - - ko00000,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA JIJKFJGP_01187 552531.BIF_00892 4.23e-171 478.0 COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4CYPS@85004|Bifidobacteriales 201174|Actinobacteria KT Response regulator receiver domain protein phoP - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C JIJKFJGP_01188 552531.BIF_00891 1.78e-202 566.0 2B59T@1|root,31Y3Y@2|Bacteria,2HZNR@201174|Actinobacteria,4D12Q@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - TPM_phosphatase JIJKFJGP_01189 552531.BIF_00890 2.56e-56 176.0 COG4842@1|root,COG4842@2|Bacteria,2GQI8@201174|Actinobacteria,4D17K@85004|Bifidobacteriales 201174|Actinobacteria S Proteins of 100 residues with WXG - - - - - - - - - - - - WXG100 JIJKFJGP_01190 1423743.JCM14108_3042 1.76e-166 500.0 COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1V1I5@1239|Firmicutes,4IG43@91061|Bacilli,3F7KN@33958|Lactobacillaceae 91061|Bacilli L DnaB-like helicase C terminal domain - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_C JIJKFJGP_01193 1033837.WANG_p1073 1.12e-121 357.0 COG4974@1|root,COG4974@2|Bacteria,1V98H@1239|Firmicutes,4HM0P@91061|Bacilli,3F5YH@33958|Lactobacillaceae 91061|Bacilli L Phage integrase, N-terminal SAM-like domain - - - - - - - - - - - - Phage_int_SAM_1,Phage_integrase JIJKFJGP_01194 1423743.JCM14108_3045 1.17e-94 285.0 COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,3F9XU@33958|Lactobacillaceae 91061|Bacilli D Cellulose biosynthesis protein BcsQ - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 JIJKFJGP_01197 1423743.JCM14108_3049 4.83e-49 164.0 2AJCU@1|root,30B90@2|Bacteria,1U7RF@1239|Firmicutes,4IHNT@91061|Bacilli,3FA2F@33958|Lactobacillaceae 91061|Bacilli S Homeodomain-like domain - - - - - - - - - - - - HTH_23 JIJKFJGP_01200 349123.Lreu23DRAFT_4711 1.45e-23 100.0 COG1476@1|root,COG1476@2|Bacteria,1VEKB@1239|Firmicutes,4HNIW@91061|Bacilli,3F6AB@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_3 JIJKFJGP_01201 891391.LAC30SC_02660 1.07e-237 662.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HA1P@91061|Bacilli,3F3WN@33958|Lactobacillaceae 91061|Bacilli L Belongs to the DNA polymerase type-Y family polYB - 2.7.7.7 ko:K02346,ko:K03502 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH JIJKFJGP_01202 324831.LGAS_1456 1.1e-25 100.0 2EIVY@1|root,33CM8@2|Bacteria,1VKJ5@1239|Firmicutes,4HRQ2@91061|Bacilli,3F7QM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - JIJKFJGP_01203 701521.PECL_1723 2.05e-255 724.0 COG0338@1|root,COG3392@1|root,COG0338@2|Bacteria,COG3392@2|Bacteria,1TRWE@1239|Firmicutes,4HD84@91061|Bacilli,3F54K@33958|Lactobacillaceae 91061|Bacilli L D12 class N6 adenine-specific DNA methyltransferase dam - 2.1.1.72 ko:K07318 - - - - ko00000,ko01000,ko02048 - - - MethyltransfD12 JIJKFJGP_01204 764298.STRMA_0737 9.28e-168 498.0 28IN4@1|root,2Z8NJ@2|Bacteria,1V00B@1239|Firmicutes 1239|Firmicutes L restriction endonuclease - - - - - - - - - - - - Endonuc-FokI_C,FokI_C,FokI_N JIJKFJGP_01207 552531.BIF_00496 0.0 1269.0 COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,4CZ1E@85004|Bifidobacteriales 201174|Actinobacteria G Alpha-amylase domain - - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - Alpha-amylase,DUF3459 JIJKFJGP_01208 552531.BIF_01682 1.4e-148 418.0 COG0406@1|root,COG0406@2|Bacteria,2GNRS@201174|Actinobacteria,4CZD2@85004|Bifidobacteriales 201174|Actinobacteria G Phosphoglycerate mutase family gpm2 GO:0003674,GO:0003824,GO:0003993,GO:0005488,GO:0005515,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0042802,GO:0042803,GO:0044237,GO:0046983 3.1.3.73 ko:K02226 ko00860,ko01100,map00860,map01100 M00122 R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000 - - - His_Phos_1 JIJKFJGP_01209 552531.BIF_01683 4.02e-89 265.0 2B5DJ@1|root,31Y80@2|Bacteria,2IRRR@201174|Actinobacteria,4D1E6@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF4235) - - - - - - - - - - - - DUF4235 JIJKFJGP_01210 552531.BIF_01684 1.44e-181 505.0 COG0778@1|root,COG0778@2|Bacteria,2I65Z@201174|Actinobacteria,4CZ5R@85004|Bifidobacteriales 201174|Actinobacteria C Nitroreductase family nfrA - - - - - - - - - - - Nitroreductase JIJKFJGP_01211 552531.BIF_01685 4.78e-59 181.0 2B78R@1|root,320BB@2|Bacteria,2IQGT@201174|Actinobacteria,4D178@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01212 552531.BIF_01686 9.5e-129 367.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily iolT - - - - - - - - - - - MFS_1,Sugar_tr JIJKFJGP_01213 552531.BIF_01760 6.52e-142 406.0 COG2008@1|root,COG2008@2|Bacteria,2GJ0V@201174|Actinobacteria,4CZ7G@85004|Bifidobacteriales 201174|Actinobacteria E Beta-eliminating lyase ltaE - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - - Beta_elim_lyase JIJKFJGP_01214 552531.BIF_00368 3.4e-300 817.0 COG0438@1|root,COG0438@2|Bacteria,2HEH6@201174|Actinobacteria,4CZSN@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 JIJKFJGP_01215 552531.BIF_00367 1.88e-295 806.0 COG0027@1|root,COG0027@2|Bacteria,2GMCS@201174|Actinobacteria,4CZXH@85004|Bifidobacteriales 201174|Actinobacteria F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate purT GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008776,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0044424,GO:0044444,GO:0044464 2.1.2.2 ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv0389 ATP-grasp,Epimerase JIJKFJGP_01216 552531.BIF_00342 4.83e-176 491.0 COG0152@1|root,COG0152@2|Bacteria,2GK3H@201174|Actinobacteria,4CZGQ@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the SAICAR synthetase family purC - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt JIJKFJGP_01220 1690.BPSG_0132 8.2e-81 239.0 COG0048@1|root,COG0048@2|Bacteria,2IHUF@201174|Actinobacteria,4D0PK@85004|Bifidobacteriales 201174|Actinobacteria J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 JIJKFJGP_01221 552531.BIF_00032 1.34e-104 302.0 COG0049@1|root,COG0049@2|Bacteria,2GMVW@201174|Actinobacteria,4CZQJ@85004|Bifidobacteriales 201174|Actinobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 JIJKFJGP_01222 552531.BIF_00045 0.0 1402.0 COG0480@1|root,COG0480@2|Bacteria,2GKB3@201174|Actinobacteria,4CYTB@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 JIJKFJGP_01223 552531.BIF_02055 7.7e-129 366.0 COG0388@1|root,COG0388@2|Bacteria,2H2H9@201174|Actinobacteria,4D0J6@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE GO:0003674,GO:0003824,GO:0003952,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.1 ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase JIJKFJGP_01224 552531.BIF_01313 0.0 888.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2H2H9@201174|Actinobacteria,4D0J6@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE GO:0003674,GO:0003824,GO:0003952,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.1 ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase JIJKFJGP_01225 552531.BIF_02196 1.24e-55 174.0 COG3077@1|root,COG3077@2|Bacteria,2GV25@201174|Actinobacteria,4D179@85004|Bifidobacteriales 201174|Actinobacteria L RelB antitoxin - - - ko:K07473 - - - - ko00000,ko02048 - - - RelB JIJKFJGP_01226 552531.BIF_01753 6.93e-193 537.0 COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria,4CZGT@85004|Bifidobacteriales 201174|Actinobacteria S Haemolysin-III related hlyIII - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII JIJKFJGP_01228 552531.BIF_01973 1.14e-196 577.0 COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,4CZJ4@85004|Bifidobacteriales 201174|Actinobacteria EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS JIJKFJGP_01229 552531.BIF_00269 5.67e-232 638.0 COG0284@1|root,COG0284@2|Bacteria,2GKWK@201174|Actinobacteria,4D2UX@85004|Bifidobacteriales 201174|Actinobacteria F Essential for recycling GMP and indirectly, cGMP pyrF - 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase JIJKFJGP_01230 552531.BIF_01846 6.35e-148 416.0 COG0194@1|root,COG0194@2|Bacteria,2I2FT@201174|Actinobacteria,4CYUT@85004|Bifidobacteriales 201174|Actinobacteria F Essential for recycling GMP and indirectly, cGMP gmk - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin JIJKFJGP_01231 1033837.WANG_0202 2.39e-136 389.0 COG3279@1|root,COG3279@2|Bacteria,1V392@1239|Firmicutes,4HHAI@91061|Bacilli,3F6AD@33958|Lactobacillaceae 91061|Bacilli K LytTr DNA-binding domain - - - ko:K07707 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg JIJKFJGP_01232 1033837.WANG_0203 4.67e-12 63.5 29NRE@1|root,309PD@2|Bacteria,1U5FQ@1239|Firmicutes,4IF74@91061|Bacilli,3F5V7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - JIJKFJGP_01233 1423748.BALB01000005_gene679 4.14e-110 319.0 COG0664@1|root,COG0664@2|Bacteria,1TVBM@1239|Firmicutes,4HEJG@91061|Bacilli,3F4PI@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, cAMP Regulatory protein crp2 - - ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding JIJKFJGP_01235 552531.BIF_01389 0.0 883.0 COG3572@1|root,COG3572@2|Bacteria,2GJPI@201174|Actinobacteria,4CYZP@85004|Bifidobacteriales 201174|Actinobacteria H Glutamate-cysteine ligase family 2(GCS2) egtA GO:0003674,GO:0003824,GO:0004357,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0044464,GO:0071944 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv3704c GCS2 JIJKFJGP_01236 552531.BIF_01467 0.0 3099.0 COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,2I1VH@201174|Actinobacteria,4CZ6Y@85004|Bifidobacteriales 201174|Actinobacteria I CoA enzyme activase uncharacterised domain (DUF2229) hgdC - - - - - - - - - - - BcrAD_BadFG,DUF2229,HGD-D JIJKFJGP_01237 552531.BIF_02181 8.85e-131 372.0 COG3548@1|root,COG3548@2|Bacteria,2GV52@201174|Actinobacteria,4D1FN@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF1211) - - - - - - - - - - - - DUF1211 JIJKFJGP_01238 31954.BPSP_1482 5.83e-78 241.0 COG3548@1|root,COG3759@1|root,COG3548@2|Bacteria,COG3759@2|Bacteria,2IRV5@201174|Actinobacteria,4D1BZ@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF1304) - - - ko:K08987 - - - - ko00000 - - - DUF1304 JIJKFJGP_01239 552531.BIF_01469 3.76e-183 512.0 2AUIM@1|root,31K74@2|Bacteria,2IKCM@201174|Actinobacteria,4D0UW@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01240 552531.BIF_01470 2.07e-190 527.0 COG0602@1|root,COG0602@2|Bacteria,2H0HA@201174|Actinobacteria,4CYSC@85004|Bifidobacteriales 201174|Actinobacteria O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine nrdG - 1.97.1.4 ko:K04068 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM JIJKFJGP_01241 552531.BIF_01471 0.0 1662.0 COG1328@1|root,COG1328@2|Bacteria,2GMGA@201174|Actinobacteria,4CYV3@85004|Bifidobacteriales 201174|Actinobacteria F Anaerobic ribonucleoside-triphosphate reductase nrdD - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - ATP-cone,NRDD JIJKFJGP_01242 552531.BIF_00285 1.04e-305 834.0 COG1570@1|root,COG1570@2|Bacteria,2GJAS@201174|Actinobacteria,4CZU4@85004|Bifidobacteriales 201174|Actinobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 JIJKFJGP_01243 552531.BIF_01935 4.21e-60 186.0 COG1722@1|root,COG1722@2|Bacteria,2GR0U@201174|Actinobacteria,4D18C@85004|Bifidobacteriales 201174|Actinobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S JIJKFJGP_01244 552531.BIF_01936 7.29e-244 670.0 COG3568@1|root,COG3568@2|Bacteria,2I2GX@201174|Actinobacteria,4CYTX@85004|Bifidobacteriales 201174|Actinobacteria S Endonuclease/Exonuclease/phosphatase family - - - ko:K18353 ko01502,ko02020,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01504 - - - Exo_endo_phos JIJKFJGP_01246 552531.BIF_00430 5.11e-165 463.0 28XY7@1|root,2ZJU4@2|Bacteria,2GN31@201174|Actinobacteria,4CZQG@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4391) tmp1 - - - - - - - - - - - DUF4391 JIJKFJGP_01247 552531.BIF_00004 2.09e-217 608.0 COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4CZQP@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase class-V aspB - 2.6.1.1,2.6.1.2,2.6.1.66 ko:K00812,ko:K08969,ko:K10907,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00034 R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052,R07396 RC00006,RC00008,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 JIJKFJGP_01248 552531.BIF_00005 1.34e-130 370.0 COG3727@1|root,COG3727@2|Bacteria,2IKPY@201174|Actinobacteria,4D0R6@85004|Bifidobacteriales 201174|Actinobacteria L May nick specific sequences that contain T G mispairs resulting from m5C-deamination vsr - - ko:K07458 - - - - ko00000,ko01000,ko03400 - - - Vsr JIJKFJGP_01249 552531.BIF_00652 0.0 1031.0 COG4279@1|root,COG4279@2|Bacteria,2GJ39@201174|Actinobacteria,4CZC0@85004|Bifidobacteriales 201174|Actinobacteria S zinc finger - - - - - - - - - - - - - JIJKFJGP_01250 552531.BIF_00664 0.0 930.0 COG0847@1|root,COG0847@2|Bacteria,2IC59@201174|Actinobacteria,4CZY1@85004|Bifidobacteriales 201174|Actinobacteria L Psort location Cytoplasmic, score - - - - - - - - - - - - - JIJKFJGP_01251 552531.BIF_00531 1.64e-162 454.0 COG0242@1|root,COG0242@2|Bacteria,2GNZ9@201174|Actinobacteria,4CZ7M@85004|Bifidobacteriales 201174|Actinobacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase JIJKFJGP_01252 552531.BIF_00530 0.0 877.0 COG1109@1|root,COG1109@2|Bacteria,2GN87@201174|Actinobacteria,4CYZX@85004|Bifidobacteriales 201174|Actinobacteria G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM GO:0008150,GO:0040007 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV JIJKFJGP_01253 552531.BIF_00521 0.0 1753.0 COG0308@1|root,COG0308@2|Bacteria,2GJJ4@201174|Actinobacteria,4CZH4@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase family M1 domain pepN - 3.4.11.2 ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 JIJKFJGP_01254 552531.BIF_01983 0.0 1228.0 COG0595@1|root,COG0595@2|Bacteria,2GIW7@201174|Actinobacteria,4CZEJ@85004|Bifidobacteriales 201174|Actinobacteria J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnj - - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,Lactamase_B_2,RMMBL JIJKFJGP_01255 552531.BIF_00297 3.72e-212 586.0 COG0329@1|root,COG0329@2|Bacteria,2GJ34@201174|Actinobacteria,4CZ34@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS JIJKFJGP_01256 552531.BIF_00298 7.91e-173 484.0 COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,4CZJ5@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB - 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - - DapB_C,DapB_N JIJKFJGP_01257 552531.BIF_00632 0.0 904.0 COG2271@1|root,COG2271@2|Bacteria,2I2GK@201174|Actinobacteria,4CZ0T@85004|Bifidobacteriales 201174|Actinobacteria G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 JIJKFJGP_01258 552531.BIF_00631 2.04e-171 478.0 COG0454@1|root,COG0454@2|Bacteria,2IKFK@201174|Actinobacteria,4D0XC@85004|Bifidobacteriales 201174|Actinobacteria K -acetyltransferase - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 JIJKFJGP_01259 552531.BIF_00621 0.0 2639.0 COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GM2E@201174|Actinobacteria,4CZ49@85004|Bifidobacteriales 201174|Actinobacteria L Belongs to the helicase family. UvrD subfamily uvrD2 - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C JIJKFJGP_01260 552531.BIF_00717 0.0 2975.0 COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GJD0@201174|Actinobacteria,4CYQU@85004|Bifidobacteriales 201174|Actinobacteria L PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - AAA_19,PDDEXK_1,UvrD-helicase,UvrD_C JIJKFJGP_01261 552531.BIF_00451 0.0 936.0 COG0515@1|root,COG0515@2|Bacteria,2GIW5@201174|Actinobacteria,4CZ9N@85004|Bifidobacteriales 201174|Actinobacteria KLT Protein tyrosine kinase pknK - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase JIJKFJGP_01262 552531.BIF_00994 0.0 3798.0 COG4733@1|root,COG4733@2|Bacteria,2GMKC@201174|Actinobacteria,4CZFT@85004|Bifidobacteriales 201174|Actinobacteria S Fibronectin type 3 domain - - - - - - - - - - - - fn3 JIJKFJGP_01263 33905.BTHE_1513 9.88e-163 471.0 COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4CZ3M@85004|Bifidobacteriales 201174|Actinobacteria S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 JIJKFJGP_01264 552531.BIF_01981 3.4e-266 732.0 COG1721@1|root,COG1721@2|Bacteria,2GIWE@201174|Actinobacteria,4CZWT@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 JIJKFJGP_01265 552531.BIF_00582 0.0 1630.0 COG1305@1|root,COG1305@2|Bacteria,2HQBB@201174|Actinobacteria,4CZ3X@85004|Bifidobacteriales 201174|Actinobacteria E Transglutaminase-like superfamily - - - - - - - - - - - - Transglut_core JIJKFJGP_01266 552531.BIF_00249 5.62e-135 385.0 COG5602@1|root,COG5602@2|Bacteria,2GRHT@201174|Actinobacteria,4D0W6@85004|Bifidobacteriales 201174|Actinobacteria B Belongs to the OprB family - - - - - - - - - - - - - JIJKFJGP_01267 552531.BIF_00248 1.49e-138 393.0 COG1716@1|root,COG1716@2|Bacteria,2IIXF@201174|Actinobacteria,4D0UU@85004|Bifidobacteriales 201174|Actinobacteria T Forkhead associated domain - - - - - - - - - - - - FHA JIJKFJGP_01268 552531.BIF_00211 0.0 2604.0 COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4CZ1D@85004|Bifidobacteriales 201174|Actinobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 JIJKFJGP_01269 552531.BIF_01034 0.0 2360.0 COG0085@1|root,COG0085@2|Bacteria,2GJ81@201174|Actinobacteria,4CZ3W@85004|Bifidobacteriales 201174|Actinobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB - 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 JIJKFJGP_01270 1690.BPSG_0971 2.17e-68 216.0 2E5CN@1|root,3304R@2|Bacteria,2I2GJ@201174|Actinobacteria,4D0SD@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01271 552531.BIF_00775 5.51e-239 657.0 COG1194@1|root,COG1194@2|Bacteria,2GJD9@201174|Actinobacteria,4CYRB@85004|Bifidobacteriales 201174|Actinobacteria L FES mutY GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD JIJKFJGP_01272 552531.BIF_00774 3.3e-165 461.0 COG0219@1|root,COG0219@2|Bacteria,2IHN9@201174|Actinobacteria,4CZ0E@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily spoU - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase JIJKFJGP_01273 552531.BIF_00665 0.0 876.0 COG2848@1|root,COG2848@2|Bacteria,2HHMF@201174|Actinobacteria,4CZGB@85004|Bifidobacteriales 201174|Actinobacteria S UPF0210 protein - - - ko:K09157 - - - - ko00000 - - - DUF711 JIJKFJGP_01274 552531.BIF_00666 1.69e-57 178.0 COG3830@1|root,COG3830@2|Bacteria,2IKS1@201174|Actinobacteria,4D11D@85004|Bifidobacteriales 201174|Actinobacteria T Belongs to the UPF0237 family - - - ko:K07166 - - - - ko00000 - - - ACT_6 JIJKFJGP_01275 552531.BIF_00667 1.45e-192 540.0 COG3764@1|root,COG3764@2|Bacteria,2GNWT@201174|Actinobacteria,4CZMM@85004|Bifidobacteriales 201174|Actinobacteria M Sortase family - - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase JIJKFJGP_01277 552531.BIF_01979 3.52e-295 806.0 COG0153@1|root,COG0153@2|Bacteria,2GJXI@201174|Actinobacteria,4CZNV@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the GHMP kinase family. GalK subfamily galK - 2.7.1.6,2.7.7.12 ko:K00849,ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955,R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 - - - GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg JIJKFJGP_01278 552531.BIF_01978 0.0 886.0 COG1085@1|root,COG1085@2|Bacteria,2I2DM@201174|Actinobacteria,4CYXZ@85004|Bifidobacteriales 201174|Actinobacteria C Galactose-1-phosphate uridyl transferase, N-terminal domain galT - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GalP_UDP_tr_C,GalP_UDP_transf JIJKFJGP_01279 552531.BIF_01940 5.19e-184 513.0 COG1349@1|root,COG1349@2|Bacteria,2H5X4@201174|Actinobacteria,4CZMT@85004|Bifidobacteriales 201174|Actinobacteria K DeoR C terminal sensor domain - - - - - - - - - - - - DeoRC,HTH_DeoR JIJKFJGP_01280 35760.BCHO_0710 9.89e-143 414.0 COG1216@1|root,COG1216@2|Bacteria,2I2FA@201174|Actinobacteria,4CZIH@85004|Bifidobacteriales 201174|Actinobacteria S Glycosyl transferase family 2 ppm1 - 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 - R01009 RC00005 ko00000,ko00001,ko01000,ko01003 - GT2 - Glycos_transf_2 JIJKFJGP_01281 552531.BIF_00336 2.16e-282 788.0 COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4CYWW@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor pyrD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.3.5.2,1.3.98.1 ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01867,R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh JIJKFJGP_01282 552531.BIF_00471 2.6e-282 770.0 COG1902@1|root,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,4CZ9Z@85004|Bifidobacteriales 201174|Actinobacteria C NADH:flavin oxidoreductase / NADH oxidase family namA - - - - - - - - - - - Oxidored_FMN JIJKFJGP_01283 552531.BIF_00394 0.0 1446.0 COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4CZAZ@85004|Bifidobacteriales 201174|Actinobacteria M Transglycosylase pon1 - - - - - - - - - - - PASTA,Transgly,Transpeptidase JIJKFJGP_01284 552531.BIF_00395 1.64e-178 498.0 COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4CYYW@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, cAMP Regulatory protein crp - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding JIJKFJGP_01285 552531.BIF_00118 5.28e-283 773.0 COG0095@1|root,COG0095@2|Bacteria,2GJV5@201174|Actinobacteria,4CZYA@85004|Bifidobacteriales 201174|Actinobacteria H Biotin/lipoate A/B protein ligase family lplA - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB JIJKFJGP_01286 552531.BIF_01866 5.69e-105 303.0 COG2314@1|root,COG2314@2|Bacteria,2IQB3@201174|Actinobacteria,4D11Z@85004|Bifidobacteriales 201174|Actinobacteria J TM2 domain - - - - - - - - - - - - TM2 JIJKFJGP_01287 552531.BIF_02147 1.84e-28 101.0 2B40I@1|root,31WQS@2|Bacteria,2GXRX@201174|Actinobacteria,4D1NZ@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01288 35760.BCHO_0702 1.06e-220 612.0 COG0473@1|root,COG0473@2|Bacteria,2GK44@201174|Actinobacteria,4CZ08@85004|Bifidobacteriales 201174|Actinobacteria CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh JIJKFJGP_01289 552531.BIF_00168 0.0 1639.0 COG1770@1|root,COG1770@2|Bacteria,2GNA9@201174|Actinobacteria,4CZ2X@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase, S9A B C family, catalytic domain protein ptrB - 3.4.21.83 ko:K01354 ko05142,ko05143,map05142,map05143 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N JIJKFJGP_01290 552531.BIF_00093 0.0 991.0 COG4850@1|root,COG4850@2|Bacteria,2GKPS@201174|Actinobacteria,4CZ13@85004|Bifidobacteriales 201174|Actinobacteria S Uncharacterized conserved protein (DUF2183) - - - - - - - - - - - - DUF2183 JIJKFJGP_01291 552531.BIF_01867 5.74e-94 274.0 COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4D0W7@85004|Bifidobacteriales 201174|Actinobacteria E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H JIJKFJGP_01292 552531.BIF_00629 2.11e-273 747.0 COG2816@1|root,COG2816@2|Bacteria,2GJZY@201174|Actinobacteria,4CZE5@85004|Bifidobacteriales 201174|Actinobacteria L NADH pyrophosphatase zinc ribbon domain nudC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.1.22 ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 - R00103,R03004,R11104 RC00002 ko00000,ko00001,ko01000 - - - NUDIX,NUDIX-like,zf-NADH-PPase JIJKFJGP_01293 552531.BIF_01287 3.34e-220 607.0 COG2267@1|root,COG2267@2|Bacteria,2I2GI@201174|Actinobacteria,4CYXW@85004|Bifidobacteriales 201174|Actinobacteria I Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 JIJKFJGP_01294 401473.BDP_1813 1.69e-113 329.0 COG1051@1|root,COG1051@2|Bacteria,2GJGZ@201174|Actinobacteria,4CYT1@85004|Bifidobacteriales 201174|Actinobacteria F Domain of unknown function (DUF4916) - - - - - - - - - - - - DUF4916 JIJKFJGP_01295 552531.BIF_01289 1.18e-86 255.0 COG0526@1|root,COG0526@2|Bacteria,2IKP1@201174|Actinobacteria,4D11J@85004|Bifidobacteriales 201174|Actinobacteria O Belongs to the thioredoxin family trxA - 1.8.1.9 ko:K00384,ko:K03671 ko00450,ko04621,ko05418,map00450,map04621,map05418 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000,ko03110 - - - Thioredoxin JIJKFJGP_01296 552531.BIF_01290 3.66e-241 664.0 COG3583@1|root,COG3583@2|Bacteria,2I2GH@201174|Actinobacteria,4CYVC@85004|Bifidobacteriales 201174|Actinobacteria S G5 - - - ko:K21688 - - - - ko00000 - - - DUF348,G5,SLT JIJKFJGP_01297 552531.BIF_00983 0.0 1007.0 COG2148@1|root,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4CZ4J@85004|Bifidobacteriales 201174|Actinobacteria M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - - - - - - - - - - Bac_transf,CoA_binding_3 JIJKFJGP_01298 552531.BIF_00982 1.57e-100 291.0 28PY9@1|root,2ZCI0@2|Bacteria,2INBV@201174|Actinobacteria,4D13Q@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01299 552531.BIF_00465 0.0 942.0 COG4713@1|root,COG4713@2|Bacteria,2IGQF@201174|Actinobacteria,4D0RE@85004|Bifidobacteriales 201174|Actinobacteria S Predicted membrane protein (DUF2142) - - - - - - - - - - - - DUF2142 JIJKFJGP_01300 552531.BIF_01807 3.45e-239 657.0 COG0463@1|root,COG0463@2|Bacteria,2I2GR@201174|Actinobacteria,4CZTN@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 JIJKFJGP_01301 552531.BIF_01545 0.0 1253.0 COG2976@1|root,COG2976@2|Bacteria,2GNIS@201174|Actinobacteria,4CZXM@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF4012) - - - - - - - - - - - - DUF4012 JIJKFJGP_01302 552531.BIF_01544 8.58e-218 600.0 COG1209@1|root,COG1209@2|Bacteria,2GP20@201174|Actinobacteria,4CZ5F@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis rfbA GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005996,GO:0006006,GO:0006139,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009117,GO:0009141,GO:0009147,GO:0009200,GO:0009211,GO:0009219,GO:0009225,GO:0009226,GO:0009262,GO:0009394,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019299,GO:0019300,GO:0019305,GO:0019318,GO:0019319,GO:0019438,GO:0019637,GO:0019692,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0045226,GO:0046075,GO:0046364,GO:0046379,GO:0046383,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv0334 NTP_transferase JIJKFJGP_01303 552531.BIF_01543 0.0 991.0 COG1091@1|root,COG1898@1|root,COG1091@2|Bacteria,COG1898@2|Bacteria,2GNY8@201174|Actinobacteria,4CZ18@85004|Bifidobacteriales 201174|Actinobacteria M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rfbD - 1.1.1.133,5.1.3.13 ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777,R06514 RC00182,RC01531 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind,dTDP_sugar_isom JIJKFJGP_01304 552531.BIF_01541 1.28e-263 720.0 COG1088@1|root,COG1088@2|Bacteria,2GNDU@201174|Actinobacteria,4CZZY@85004|Bifidobacteriales 201174|Actinobacteria M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv3464 GDP_Man_Dehyd JIJKFJGP_01305 552531.BIF_01904 4.52e-237 651.0 COG0463@1|root,COG0463@2|Bacteria,2GKGN@201174|Actinobacteria,4D0WX@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 JIJKFJGP_01306 552531.BIF_01540 0.0 924.0 COG2244@1|root,COG2244@2|Bacteria,2IA1K@201174|Actinobacteria,4D0KU@85004|Bifidobacteriales 201174|Actinobacteria S Psort location CytoplasmicMembrane, score 9.99 - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C JIJKFJGP_01307 552531.BIF_01539 6.8e-219 603.0 COG1216@1|root,COG1216@2|Bacteria,2I9I3@201174|Actinobacteria,4CZKP@85004|Bifidobacteriales 201174|Actinobacteria S Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 JIJKFJGP_01308 552531.BIF_01538 4.03e-245 673.0 COG1216@1|root,COG1216@2|Bacteria,2I2EQ@201174|Actinobacteria,4D2VS@85004|Bifidobacteriales 201174|Actinobacteria S Glycosyltransferase like family 2 - - 2.7.8.12 ko:K09809,ko:K19427 - - - - ko00000,ko01000 - GT2 - Glycos_transf_2 JIJKFJGP_01309 552531.BIF_01537 0.0 880.0 2DI34@1|root,301W1@2|Bacteria,2HA7T@201174|Actinobacteria,4D2PC@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01310 552531.BIF_01520 6.81e-220 605.0 COG1216@1|root,COG1216@2|Bacteria,2IC7I@201174|Actinobacteria,4D0F6@85004|Bifidobacteriales 201174|Actinobacteria S Glycosyl transferase family 2 - - - ko:K12990 ko02024,ko02025,map02024,map02025 - - - ko00000,ko00001,ko01000,ko01003,ko01005 - GT2 - Glycos_transf_2 JIJKFJGP_01311 552531.BIF_01521 9.26e-187 519.0 COG1442@1|root,COG1442@2|Bacteria,2HFT7@201174|Actinobacteria,4CZBS@85004|Bifidobacteriales 201174|Actinobacteria M Domain of unknown function (DUF4422) - - - - - - - - - - - - DUF4422 JIJKFJGP_01312 552531.BIF_01522 1.34e-210 582.0 COG1216@1|root,COG1216@2|Bacteria,2HZAH@201174|Actinobacteria,4CZBT@85004|Bifidobacteriales 201174|Actinobacteria S Glycosyltransferase like family 2 - - - ko:K12992 ko02025,map02025 - - - ko00000,ko00001,ko01000,ko01003,ko01005 - GT2 - Glycos_transf_2 JIJKFJGP_01313 552531.BIF_02150 3.61e-234 645.0 COG3774@1|root,COG3774@2|Bacteria,2ICTC@201174|Actinobacteria,4D0R2@85004|Bifidobacteriales 201174|Actinobacteria M Capsular polysaccharide synthesis protein - - - - - - - - - - - - Caps_synth JIJKFJGP_01314 552531.BIF_01523 5.09e-302 823.0 COG1004@1|root,COG1004@2|Bacteria,2GJQB@201174|Actinobacteria,4CZ1N@85004|Bifidobacteriales 201174|Actinobacteria M UDP binding domain ugd - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N JIJKFJGP_01315 552531.BIF_02151 0.0 881.0 COG2244@1|root,COG2244@2|Bacteria,2IA1K@201174|Actinobacteria,4D0KU@85004|Bifidobacteriales 201174|Actinobacteria S Psort location CytoplasmicMembrane, score 9.99 - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C JIJKFJGP_01316 552531.BIF_02152 1.53e-252 691.0 COG0438@1|root,COG0438@2|Bacteria,2H5HU@201174|Actinobacteria 201174|Actinobacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - - JIJKFJGP_01317 552531.BIF_01903 4.92e-208 575.0 COG1216@1|root,COG1216@2|Bacteria,2IC7I@201174|Actinobacteria,4D0F6@85004|Bifidobacteriales 201174|Actinobacteria S Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 JIJKFJGP_01318 552531.BIF_00944 0.0 990.0 COG2148@1|root,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4CZ4J@85004|Bifidobacteriales 201174|Actinobacteria M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - - - - - - - - - - Bac_transf,CoA_binding_3 JIJKFJGP_01319 552531.BIF_00945 2.01e-65 200.0 2AVIH@1|root,31MB1@2|Bacteria,2IMY2@201174|Actinobacteria,4D12K@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01320 552531.BIF_00009 0.0 1108.0 COG0477@1|root,COG2814@2|Bacteria,2GIZX@201174|Actinobacteria,4CZWX@85004|Bifidobacteriales 201174|Actinobacteria U Drug resistance MFS transporter, drug H antiporter-2 family - - - - - - - - - - - - MFS_1 JIJKFJGP_01321 552531.BIF_01572 6.59e-310 846.0 COG1914@1|root,COG1914@2|Bacteria,2GJSM@201174|Actinobacteria,4CZZB@85004|Bifidobacteriales 201174|Actinobacteria P H( )-stimulated, divalent metal cation uptake system mntH GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0030001,GO:0034220,GO:0034755,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071421,GO:0071577,GO:0071578,GO:0072511,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098739,GO:0099587 - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp JIJKFJGP_01322 552531.BIF_01573 1.3e-174 487.0 COG2356@1|root,COG2356@2|Bacteria,2GJ38@201174|Actinobacteria,4CZCY@85004|Bifidobacteriales 201174|Actinobacteria L Protein of unknown function (DUF1524) - - - - - - - - - - - - DUF1524 JIJKFJGP_01323 552531.BIF_01575 2.31e-199 553.0 COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria,4CZ5P@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively pdxS GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 ko:K06215 ko00750,map00750 - R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 - - - SOR_SNZ JIJKFJGP_01324 552531.BIF_01576 2.15e-153 431.0 COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria,4CYUS@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS pdxT GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 ko:K08681 ko00750,map00750 - R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 - - - SNO JIJKFJGP_01325 552531.BIF_01577 2.14e-282 770.0 COG0451@1|root,COG0451@2|Bacteria,2I2UT@201174|Actinobacteria 201174|Actinobacteria M epimerase dehydratase - - - - - - - - - - - - Epimerase,GDP_Man_Dehyd JIJKFJGP_01326 552531.BIF_01578 6.41e-111 318.0 COG0707@1|root,COG0707@2|Bacteria,2IKNK@201174|Actinobacteria,4D1E5@85004|Bifidobacteriales 201174|Actinobacteria M Oligosaccharide biosynthesis protein Alg14 like - - - - - - - - - - - - Alg14,Glyco_tran_28_C JIJKFJGP_01327 552531.BIF_01579 1.84e-119 341.0 COG5017@1|root,COG5017@2|Bacteria,2HEQD@201174|Actinobacteria,4D1BS@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyltransferase family 28 C-terminal domain - - - - - - - - - - - - Glyco_tran_28_C JIJKFJGP_01328 552531.BIF_01874 1.66e-181 507.0 COG1216@1|root,COG1216@2|Bacteria,2IC7I@201174|Actinobacteria,4CZB7@85004|Bifidobacteriales 201174|Actinobacteria S Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 JIJKFJGP_01329 552531.BIF_01875 5.53e-205 566.0 COG1216@1|root,COG1216@2|Bacteria,2IC7I@201174|Actinobacteria,4D0F6@85004|Bifidobacteriales 201174|Actinobacteria S Glycosyl transferase family 2 - - - ko:K12990 ko02024,ko02025,map02024,map02025 - - - ko00000,ko00001,ko01000,ko01003,ko01005 - GT2 - Glycos_transf_2 JIJKFJGP_01330 552531.BIF_02025 8.76e-261 716.0 2BKUQ@1|root,32FB3@2|Bacteria,2HD18@201174|Actinobacteria 201174|Actinobacteria S EpsG family - - - - - - - - - - - - EpsG JIJKFJGP_01331 552531.BIF_02024 0.0 2221.0 COG1132@1|root,COG4988@1|root,COG1132@2|Bacteria,COG4988@2|Bacteria,2GITR@201174|Actinobacteria,4CYSB@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter transmembrane region - - - ko:K06147,ko:K06148,ko:K16013 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.129,3.A.1.21 - - ABC_membrane,ABC_tran JIJKFJGP_01332 552531.BIF_01159 0.0 1201.0 COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4CYVD@85004|Bifidobacteriales 201174|Actinobacteria I long-chain-fatty acid CoA ligase fadD - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding JIJKFJGP_01333 552531.BIF_02184 0.0 937.0 COG0424@1|root,COG1051@1|root,COG0424@2|Bacteria,COG1051@2|Bacteria,2GNI0@201174|Actinobacteria,4CZXF@85004|Bifidobacteriales 201174|Actinobacteria DF Maf-like protein maf GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - ko:K06287 - - - - ko00000 - - - Maf,NUDIX JIJKFJGP_01334 552531.BIF_01478 1.13e-132 376.0 COG0394@1|root,COG0394@2|Bacteria,2GMPR@201174|Actinobacteria,4D0GD@85004|Bifidobacteriales 201174|Actinobacteria T Low molecular weight phosphatase family etp - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc JIJKFJGP_01335 552531.BIF_01477 0.0 1103.0 COG2976@1|root,COG2976@2|Bacteria,2GNIS@201174|Actinobacteria,4D2V4@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF4012) - - - - - - - - - - - - DUF4012 JIJKFJGP_01336 552531.BIF_01476 0.0 926.0 COG0489@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3944@2|Bacteria,2GJ1Y@201174|Actinobacteria,4CZKW@85004|Bifidobacteriales 201174|Actinobacteria DM Psort location CytoplasmicMembrane, score wcoI - - - - - - - - - - - AAA_31,CbiA,GNVR,ParA,Wzz JIJKFJGP_01337 552531.BIF_01475 6.14e-110 326.0 2B5EF@1|root,31Y8Y@2|Bacteria,2H0E3@201174|Actinobacteria,4D1S5@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01339 552531.BIF_02023 0.0 875.0 COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4D1TR@85004|Bifidobacteriales 201174|Actinobacteria L Transposase tnpA - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 JIJKFJGP_01340 748671.LCRIS_00062 6.57e-49 158.0 2DMNG@1|root,32SP1@2|Bacteria,1VAXC@1239|Firmicutes,4HM1Q@91061|Bacilli,3F8QG@33958|Lactobacillaceae 91061|Bacilli S COG NOG14552 non supervised orthologous group - - - - - - - - - - - - - JIJKFJGP_01341 552531.BIF_00469 5.43e-158 451.0 COG1653@1|root,COG1653@2|Bacteria,2GWCY@201174|Actinobacteria,4CYWG@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein amyE - - ko:K10117 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - SBP_bac_8 JIJKFJGP_01342 891391.LAC30SC_02360 9.8e-177 501.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,4HC8M@91061|Bacilli,3FCFA@33958|Lactobacillaceae 91061|Bacilli L COG2963 Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 JIJKFJGP_01343 1423767.BALU01000013_gene78 5.83e-133 387.0 COG3547@1|root,COG3547@2|Bacteria,1TP4A@1239|Firmicutes,4HDAB@91061|Bacilli,3F40X@33958|Lactobacillaceae 91061|Bacilli L COG3547 Transposase and inactivated derivatives - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 JIJKFJGP_01344 552531.BIF_00889 0.0 874.0 COG1479@1|root,COG1479@2|Bacteria,2I99F@201174|Actinobacteria,4CZ4G@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function DUF262 - - - - - - - - - - - - DUF1524,DUF262 JIJKFJGP_01345 552531.BIF_00888 3.31e-158 445.0 COG0110@1|root,COG0110@2|Bacteria,2GNUB@201174|Actinobacteria,4CZ5K@85004|Bifidobacteriales 201174|Actinobacteria S Bacterial transferase hexapeptide repeat protein - - 2.3.1.18,2.3.1.79 ko:K00633,ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac JIJKFJGP_01346 552531.BIF_01820 3.99e-47 152.0 2BKI1@1|root,32EZ7@2|Bacteria,2GY4P@201174|Actinobacteria,4D1T4@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01347 552531.BIF_00057 0.0 1806.0 COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4CZ3T@85004|Bifidobacteriales 201174|Actinobacteria C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C JIJKFJGP_01348 552531.BIF_00241 0.0 1647.0 COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4CYS1@85004|Bifidobacteriales 201174|Actinobacteria P E1-E2 ATPase ctpE GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 - ko:K12952 - - - - ko00000,ko01000 3.A.3.23 - - E1-E2_ATPase,Hydrolase JIJKFJGP_01349 552531.BIF_00688 3.81e-133 382.0 2AVVG@1|root,31MP9@2|Bacteria,2INFG@201174|Actinobacteria,4D12J@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - Peripla_BP_4 JIJKFJGP_01350 552531.BIF_01331 0.0 887.0 COG2265@1|root,COG2265@2|Bacteria,2GIR3@201174|Actinobacteria,4CYYN@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr JIJKFJGP_01351 552531.BIF_01330 2.68e-176 492.0 2AVV0@1|root,31MNQ@2|Bacteria,2GJKP@201174|Actinobacteria,4CYQX@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3159) - - - - - - - - - - - - DUF3159 JIJKFJGP_01352 552531.BIF_01329 5.41e-204 565.0 28J4D@1|root,30NZ9@2|Bacteria,2I2E9@201174|Actinobacteria,4D2VD@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3710) - - - - - - - - - - - - DUF3710 JIJKFJGP_01353 552531.BIF_01328 4.59e-217 597.0 COG0708@1|root,COG0708@2|Bacteria,2GKIS@201174|Actinobacteria,4CYVB@85004|Bifidobacteriales 201174|Actinobacteria L Endonuclease/Exonuclease/phosphatase family xth - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos JIJKFJGP_01354 552531.BIF_01327 2.11e-153 431.0 2AS2F@1|root,31HF0@2|Bacteria,2IGQ8@201174|Actinobacteria,4D0TD@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01355 552531.BIF_02143 0.0 1319.0 COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,4CYU0@85004|Bifidobacteriales 201174|Actinobacteria P Belongs to the ABC transporter superfamily dppD - - ko:K02031,ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY JIJKFJGP_01356 552531.BIF_00040 9.25e-220 608.0 COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4CYQF@85004|Bifidobacteriales 201174|Actinobacteria EP N-terminal TM domain of oligopeptide transport permease C dppC - - ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N JIJKFJGP_01357 31954.BPSP_1163 1.48e-199 555.0 COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4CZSV@85004|Bifidobacteriales 201174|Actinobacteria EP Binding-protein-dependent transport system inner membrane component dppB - - ko:K02033,ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 JIJKFJGP_01358 552531.BIF_00737 0.0 1093.0 COG4166@1|root,COG4166@2|Bacteria,2GIUH@201174|Actinobacteria,4CZFK@85004|Bifidobacteriales 201174|Actinobacteria E ABC transporter, substrate-binding protein, family 5 dppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 JIJKFJGP_01359 552531.BIF_00736 1.44e-228 629.0 COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CZCX@85004|Bifidobacteriales 201174|Actinobacteria D Belongs to the 'phage' integrase family. XerC subfamily xerC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase JIJKFJGP_01360 552531.BIF_01800 4.76e-190 530.0 COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4CZ04@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter, ATP-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran JIJKFJGP_01361 552531.BIF_00002 0.0 1708.0 COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2GJTZ@201174|Actinobacteria,4CZIE@85004|Bifidobacteriales 201174|Actinobacteria MV MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD JIJKFJGP_01362 552531.BIF_02140 3.14e-54 170.0 2BGJ3@1|root,32AHC@2|Bacteria,2IR91@201174|Actinobacteria,4D17H@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01363 552531.BIF_00146 7.85e-270 738.0 COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria,4CYV2@85004|Bifidobacteriales 201174|Actinobacteria E Prephenate dehydrogenase tyrA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12 ko:K00210,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - - PDH JIJKFJGP_01364 552531.BIF_00702 6.3e-277 756.0 COG0077@1|root,COG0077@2|Bacteria,2GJQ5@201174|Actinobacteria,4CZ61@85004|Bifidobacteriales 201174|Actinobacteria E Prephenate dehydratase pheA - 4.2.1.51,5.4.99.5 ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715 RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 - - - ACT,PDT JIJKFJGP_01365 552531.BIF_02139 2.34e-118 340.0 2E9EF@1|root,333MW@2|Bacteria,2IKWQ@201174|Actinobacteria,4D10T@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01366 552531.BIF_01335 0.0 1266.0 COG1217@1|root,COG1217@2|Bacteria,2GJUJ@201174|Actinobacteria,4CYX3@85004|Bifidobacteriales 201174|Actinobacteria T Elongation factor G C-terminus typA - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 JIJKFJGP_01367 552531.BIF_01334 0.0 907.0 COG0477@1|root,COG0477@2|Bacteria,2HC9X@201174|Actinobacteria,4D2V1@85004|Bifidobacteriales 201174|Actinobacteria U Sugar (and other) transporter nanT - - ko:K03290,ko:K08178,ko:K08369 - - - - ko00000,ko02000 2.A.1,2.A.1.12 - - MFS_1,Sugar_tr JIJKFJGP_01368 552531.BIF_02137 1.01e-200 556.0 COG1051@1|root,COG1051@2|Bacteria,2GNMT@201174|Actinobacteria,4CZNZ@85004|Bifidobacteriales 201174|Actinobacteria F NUDIX hydrolase - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX JIJKFJGP_01369 552531.BIF_01332 1.55e-194 540.0 COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4CYV4@85004|Bifidobacteriales 201174|Actinobacteria D CobQ CobB MinD ParA nucleotide binding domain protein soj GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 JIJKFJGP_01370 552531.BIF_01849 9.9e-214 591.0 COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CZ69@85004|Bifidobacteriales 201174|Actinobacteria D recombinase XerD xerD GO:0008150,GO:0040007 - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase JIJKFJGP_01371 552531.BIF_00765 1.63e-82 244.0 COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria,4D0QF@85004|Bifidobacteriales 201174|Actinobacteria J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 JIJKFJGP_01372 552531.BIF_01848 1.79e-34 118.0 COG0291@1|root,COG0291@2|Bacteria,2HZRM@201174|Actinobacteria,4D1EV@85004|Bifidobacteriales 201174|Actinobacteria J Ribosomal protein L35 rpmI - - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p JIJKFJGP_01373 552531.BIF_00766 2.25e-136 389.0 COG0290@1|root,COG0290@2|Bacteria,2GJGT@201174|Actinobacteria,4CZA3@85004|Bifidobacteriales 201174|Actinobacteria J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N JIJKFJGP_01374 552531.BIF_00939 1.68e-193 537.0 COG1564@1|root,COG1564@2|Bacteria,2HQZZ@201174|Actinobacteria,4CZBY@85004|Bifidobacteriales 201174|Actinobacteria H Thiamin pyrophosphokinase, vitamin B1 binding domain - - 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 - R00619 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TPK_B1_binding,TPK_catalytic JIJKFJGP_01375 552531.BIF_00940 1.3e-264 724.0 COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4CZ97@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N JIJKFJGP_01376 552531.BIF_00421 3.2e-116 333.0 COG2606@1|root,COG2606@2|Bacteria,2IHS8@201174|Actinobacteria,4CZFI@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily ybaK - - ko:K03976 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit JIJKFJGP_01377 552531.BIF_00898 4.77e-229 631.0 COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4CZ8B@85004|Bifidobacteriales 201174|Actinobacteria IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH - 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - - LYTB JIJKFJGP_01378 552531.BIF_00899 3.12e-253 692.0 COG2017@1|root,COG2017@2|Bacteria,2GJ0H@201174|Actinobacteria,4CYWN@85004|Bifidobacteriales 201174|Actinobacteria G Aldose 1-epimerase - - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim JIJKFJGP_01379 552531.BIF_01079 1.32e-72 217.0 29M53@1|root,3082I@2|Bacteria,2GTWX@201174|Actinobacteria,4D1EJ@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01380 552531.BIF_01078 2.85e-169 476.0 COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4CZ09@85004|Bifidobacteriales 201174|Actinobacteria K Belongs to the sigma-70 factor family. ECF subfamily sigH GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 JIJKFJGP_01381 552531.BIF_01077 0.0 1018.0 COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria,4CZAF@85004|Bifidobacteriales 201174|Actinobacteria M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M JIJKFJGP_01382 552531.BIF_00925 2e-255 701.0 COG2348@1|root,COG2348@2|Bacteria,2GJUD@201174|Actinobacteria,4CZT9@85004|Bifidobacteriales 201174|Actinobacteria V Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_6,FemAB JIJKFJGP_01383 552531.BIF_02001 0.0 1023.0 COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria,4CZG9@85004|Bifidobacteriales 201174|Actinobacteria H Mur ligase middle domain folC GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv2447c Mur_ligase_C,Mur_ligase_M JIJKFJGP_01384 552531.BIF_00156 5.94e-149 420.0 COG2197@1|root,COG2197@2|Bacteria,2INVG@201174|Actinobacteria,4D15G@85004|Bifidobacteriales 201174|Actinobacteria KT cheY-homologous receiver domain - - - - - - - - - - - - GerE,Response_reg JIJKFJGP_01385 552531.BIF_01069 2.34e-248 685.0 COG4585@1|root,COG4585@2|Bacteria,2GV4W@201174|Actinobacteria,4D1DW@85004|Bifidobacteriales 201174|Actinobacteria T Histidine kinase - - - - - - - - - - - - - JIJKFJGP_01386 552531.BIF_01068 3.55e-192 533.0 2FJDZ@1|root,34B3R@2|Bacteria,2IMV2@201174|Actinobacteria,4D2NC@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01387 552531.BIF_00643 0.0 1072.0 COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4CZIA@85004|Bifidobacteriales 201174|Actinobacteria E Aminopeptidase P, N-terminal domain pepP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 JIJKFJGP_01388 552531.BIF_00642 6.13e-127 362.0 COG1051@1|root,COG1051@2|Bacteria,2IKKB@201174|Actinobacteria,4CZS4@85004|Bifidobacteriales 201174|Actinobacteria F NUDIX domain - - - - - - - - - - - - NUDIX JIJKFJGP_01389 552531.BIF_01893 1.51e-284 778.0 COG1940@1|root,COG1940@2|Bacteria,2GJ2S@201174|Actinobacteria,4CYV9@85004|Bifidobacteriales 201174|Actinobacteria GK ROK family - - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HTH_24,MarR_2,ROK JIJKFJGP_01390 552531.BIF_00330 2.02e-217 599.0 COG0524@1|root,COG0524@2|Bacteria,2HZB3@201174|Actinobacteria,4CZFC@85004|Bifidobacteriales 201174|Actinobacteria G pfkB family carbohydrate kinase - - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB JIJKFJGP_01391 552531.BIF_00331 6.33e-109 313.0 COG1490@1|root,COG1490@2|Bacteria,2IKVR@201174|Actinobacteria,4D0VE@85004|Bifidobacteriales 201174|Actinobacteria J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase JIJKFJGP_01392 552531.BIF_01229 3.23e-271 741.0 COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4CZKR@85004|Bifidobacteriales 201174|Actinobacteria L Phage integrase family int8 - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase JIJKFJGP_01394 682795.AciX8_1411 0.00013 43.5 COG3311@1|root,COG3311@2|Bacteria,3Y5MJ@57723|Acidobacteria,2JJZN@204432|Acidobacteriia 204432|Acidobacteriia L Helix-turn-helix domain - - - - - - - - - - - - HTH_17 JIJKFJGP_01398 552531.BIF_02000 3.06e-39 130.0 2B5BY@1|root,31Y65@2|Bacteria,2H09Q@201174|Actinobacteria,4D1SF@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01399 552531.BIF_00596 4.49e-291 795.0 COG0467@1|root,COG0467@2|Bacteria,2I9WA@201174|Actinobacteria,4D0DZ@85004|Bifidobacteriales 201174|Actinobacteria T AAA domain - - - - - - - - - - - - AAA_25,Prim-Pol,Toprim_3 JIJKFJGP_01404 552531.BIF_00409 0.0 1170.0 COG3740@1|root,COG4653@1|root,COG3740@2|Bacteria,COG4653@2|Bacteria,2IC7D@201174|Actinobacteria,4D0WJ@85004|Bifidobacteriales 201174|Actinobacteria S Caudovirus prohead serine protease - - - ko:K06904 - - - - ko00000 - - - Peptidase_S78,Phage_capsid JIJKFJGP_01407 552531.BIF_00293 0.0 1106.0 COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,4CYU0@85004|Bifidobacteriales 201174|Actinobacteria P Belongs to the ABC transporter superfamily - - - ko:K02031,ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY JIJKFJGP_01408 552531.BIF_01148 3.5e-272 747.0 COG1173@1|root,COG1173@2|Bacteria,2GKAW@201174|Actinobacteria,4CZ2Y@85004|Bifidobacteriales 201174|Actinobacteria EP Binding-protein-dependent transport system inner membrane component dppC - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N JIJKFJGP_01409 552531.BIF_01149 1.98e-243 672.0 COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4CZSV@85004|Bifidobacteriales 201174|Actinobacteria EP Binding-protein-dependent transport system inner membrane component dppB - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 JIJKFJGP_01410 552531.BIF_01150 5.75e-76 229.0 COG0747@1|root,COG0747@2|Bacteria,2GMAX@201174|Actinobacteria,4D2RC@85004|Bifidobacteriales 201174|Actinobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 JIJKFJGP_01411 35760.BCHO_0338 3.14e-200 570.0 COG0747@1|root,COG0747@2|Bacteria,2GMAX@201174|Actinobacteria,4D2RC@85004|Bifidobacteriales 201174|Actinobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 JIJKFJGP_01412 552531.BIF_01151 2.95e-301 825.0 COG1589@1|root,COG1589@2|Bacteria,2H4A4@201174|Actinobacteria,4D04A@85004|Bifidobacteriales 201174|Actinobacteria D Cell division protein FtsQ ftsQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 JIJKFJGP_01413 552531.BIF_00646 0.0 989.0 COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4CZ3B@85004|Bifidobacteriales 201174|Actinobacteria M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M JIJKFJGP_01414 1690.BPSG_0661 2.95e-206 579.0 COG0707@1|root,COG0707@2|Bacteria,2GJEM@201174|Actinobacteria,4CYQS@85004|Bifidobacteriales 201174|Actinobacteria M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227,6.3.2.8 ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 - R03193,R05032,R05662 RC00005,RC00049,RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 JIJKFJGP_01415 552531.BIF_01048 0.0 897.0 COG0772@1|root,COG0772@2|Bacteria,2GKXP@201174|Actinobacteria,4CYPZ@85004|Bifidobacteriales 201174|Actinobacteria D Belongs to the SEDS family ftsW GO:0008150,GO:0040007 2.4.1.227 ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 2.A.103.1 GT28 - FTSW_RODA_SPOVE JIJKFJGP_01416 552531.BIF_00509 0.0 941.0 COG0771@1|root,COG0771@2|Bacteria,2GJZA@201174|Actinobacteria,4CZKI@85004|Bifidobacteriales 201174|Actinobacteria M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iNJ661.Rv2155c AlaDh_PNT_C,Mur_ligase_C,Mur_ligase_M JIJKFJGP_01417 552531.BIF_00379 1.21e-267 732.0 COG0472@1|root,COG0472@2|Bacteria,2GNEH@201174|Actinobacteria,4CYRX@85004|Bifidobacteriales 201174|Actinobacteria M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 JIJKFJGP_01418 552531.BIF_00378 0.0 911.0 COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,4CZ7U@85004|Bifidobacteriales 201174|Actinobacteria M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M JIJKFJGP_01419 552531.BIF_00314 9.34e-204 565.0 COG0769@1|root,COG0769@2|Bacteria,2GMZF@201174|Actinobacteria,4CYWT@85004|Bifidobacteriales 201174|Actinobacteria M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan - - - - - - - - - - - - - JIJKFJGP_01420 552531.BIF_00315 0.0 1168.0 COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,4CYS8@85004|Bifidobacteriales 201174|Actinobacteria M Penicillin-binding protein, transpeptidase domain protein ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PBP_dimer,Transpeptidase JIJKFJGP_01421 552531.BIF_01361 3.19e-119 342.0 COG2919@1|root,COG2919@2|Bacteria,2IKUA@201174|Actinobacteria,4D109@85004|Bifidobacteriales 201174|Actinobacteria D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - - - - - - - - - - - JIJKFJGP_01422 552531.BIF_01362 2.11e-249 685.0 COG0275@1|root,COG0275@2|Bacteria,2GJGK@201174|Actinobacteria,4CYRM@85004|Bifidobacteriales 201174|Actinobacteria J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 JIJKFJGP_01423 552531.BIF_01363 5.36e-111 320.0 COG2001@1|root,COG2001@2|Bacteria,2IHUB@201174|Actinobacteria,4D0P1@85004|Bifidobacteriales 201174|Actinobacteria K Belongs to the MraZ family mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K03925 - - - - ko00000 - - - MraZ JIJKFJGP_01424 552531.BIF_01364 0.0 1459.0 COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,4CYUF@85004|Bifidobacteriales 201174|Actinobacteria L DNA helicase - - - - - - - - - - - - AAA_19,UvrD_C_2,Viral_helicase1 JIJKFJGP_01425 552531.BIF_01365 1.59e-289 790.0 COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,4CYPT@85004|Bifidobacteriales 201174|Actinobacteria EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C JIJKFJGP_01426 552531.BIF_02171 1.85e-125 356.0 COG1327@1|root,COG1327@2|Bacteria,2IHU9@201174|Actinobacteria,4D0P7@85004|Bifidobacteriales 201174|Actinobacteria K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone JIJKFJGP_01427 31954.BPSP_1220 3.77e-14 70.5 COG1388@1|root,COG1388@2|Bacteria,2GWI9@201174|Actinobacteria 201174|Actinobacteria M LysM domain - - - - - - - - - - - - LysM JIJKFJGP_01428 552531.BIF_00542 1.06e-165 463.0 COG1974@1|root,COG1974@2|Bacteria,2GMBN@201174|Actinobacteria,4CZ26@85004|Bifidobacteriales 201174|Actinobacteria K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA - 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 JIJKFJGP_01429 552531.BIF_00383 2.23e-212 588.0 COG1230@1|root,COG1230@2|Bacteria,2GMRZ@201174|Actinobacteria,4CZAB@85004|Bifidobacteriales 201174|Actinobacteria P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family czcD - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux,ZT_dimer JIJKFJGP_01430 552531.BIF_00382 3.25e-225 621.0 COG0039@1|root,COG0039@2|Bacteria,2GN5S@201174|Actinobacteria,4CYWK@85004|Bifidobacteriales 201174|Actinobacteria C Belongs to the LDH MDH superfamily. LDH family ldh - 1.1.1.27,1.1.1.37 ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R00703,R01000,R03104,R07136 RC00031,RC00044 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N JIJKFJGP_01431 552531.BIF_01184 0.0 967.0 COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria,4CZCB@85004|Bifidobacteriales 201174|Actinobacteria S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 JIJKFJGP_01432 552531.BIF_01185 1.27e-150 425.0 COG2813@1|root,COG2813@2|Bacteria,2IFG7@201174|Actinobacteria,4CZP1@85004|Bifidobacteriales 201174|Actinobacteria J Ribosomal protein L11 methyltransferase (PrmA) rsmC - 2.1.1.172 ko:K00564 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS JIJKFJGP_01433 552531.BIF_01186 0.0 2649.0 COG1643@1|root,COG1643@2|Bacteria,2GIWX@201174|Actinobacteria,4CZ3C@85004|Bifidobacteriales 201174|Actinobacteria L Helicase associated domain (HA2) Add an annotation hrpA - 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - AAA_19,DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind JIJKFJGP_01434 552531.BIF_02012 0.0 914.0 COG0174@1|root,COG0174@2|Bacteria,2GJ2I@201174|Actinobacteria,4CZ0G@85004|Bifidobacteriales 201174|Actinobacteria E glutamine synthetase glnA2 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N JIJKFJGP_01435 35760.BCHO_0364 1.28e-230 649.0 COG4320@1|root,COG4320@2|Bacteria,2GKEK@201174|Actinobacteria,4CZIY@85004|Bifidobacteriales 201174|Actinobacteria S Uncharacterized protein conserved in bacteria (DUF2252) - - - - - - - - - - - - DUF2252 JIJKFJGP_01436 552531.BIF_00845 3.66e-167 468.0 COG0106@1|root,COG0106@2|Bacteria,2GJ4V@201174|Actinobacteria,4CZEA@85004|Bifidobacteriales 201174|Actinobacteria E Histidine biosynthesis protein hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16,5.3.1.24 ko:K01814,ko:K01817 ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230 M00023,M00026 R03509,R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth JIJKFJGP_01437 552531.BIF_00844 2.09e-155 436.0 COG0118@1|root,COG0118@2|Bacteria,2GIYS@201174|Actinobacteria,4CZGA@85004|Bifidobacteriales 201174|Actinobacteria E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase JIJKFJGP_01438 552531.BIF_00843 4.58e-167 468.0 2EKCN@1|root,33E2Y@2|Bacteria,2GNIC@201174|Actinobacteria,4D0B5@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01439 552531.BIF_00842 2.09e-143 404.0 COG0131@1|root,COG0131@2|Bacteria,2GKMD@201174|Actinobacteria,4CZDD@85004|Bifidobacteriales 201174|Actinobacteria E Imidazoleglycerol-phosphate dehydratase hisB GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013,R03457 RC00017,RC00932 ko00000,ko00001,ko00002,ko01000 - - - IGPD JIJKFJGP_01440 552531.BIF_00143 2.17e-287 784.0 COG0079@1|root,COG0079@2|Bacteria,2GJ9W@201174|Actinobacteria,4CZDT@85004|Bifidobacteriales 201174|Actinobacteria E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 JIJKFJGP_01441 552531.BIF_00107 0.0 889.0 COG0141@1|root,COG0141@2|Bacteria,2GKKA@201174|Actinobacteria,4CZ3E@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1599 Histidinol_dh JIJKFJGP_01442 552531.BIF_00072 4.93e-286 782.0 COG4260@1|root,COG4260@2|Bacteria,2HUEV@201174|Actinobacteria,4CZKS@85004|Bifidobacteriales 201174|Actinobacteria S Short C-terminal domain - - - - - - - - - - - - Band_7_1,DUF4339,SHOCT JIJKFJGP_01443 552531.BIF_01942 4.96e-139 392.0 2C3F9@1|root,32UDZ@2|Bacteria,2IK91@201174|Actinobacteria,4D0RF@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01444 552531.BIF_01941 2.77e-90 266.0 2AHN4@1|root,31801@2|Bacteria,2INVK@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01445 552531.BIF_00089 2.73e-162 456.0 2B6EN@1|root,31ZCK@2|Bacteria,2H1ZG@201174|Actinobacteria,4D1YP@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01446 552531.BIF_00396 0.0 876.0 2DNFW@1|root,32XAQ@2|Bacteria,2IANA@201174|Actinobacteria,4D0ED@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01448 552531.BIF_00280 1.97e-140 397.0 COG1396@1|root,COG1396@2|Bacteria,2GNWM@201174|Actinobacteria,4D0SB@85004|Bifidobacteriales 201174|Actinobacteria K sequence-specific DNA binding - - - - - - - - - - - - - JIJKFJGP_01449 552531.BIF_00279 1.97e-116 334.0 COG3467@1|root,COG3467@2|Bacteria,2IGUA@201174|Actinobacteria,4D0SF@85004|Bifidobacteriales 201174|Actinobacteria S Pyridoxamine 5'-phosphate oxidase - - - ko:K07005 - - - - ko00000 - - - Pyridox_ox_2 JIJKFJGP_01450 552531.BIF_01862 1.21e-130 372.0 2AIHW@1|root,318ZT@2|Bacteria,2I9DK@201174|Actinobacteria,4D0J0@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01451 552531.BIF_00063 9.81e-297 811.0 COG1100@1|root,COG1100@2|Bacteria,2I2HM@201174|Actinobacteria,4D0JM@85004|Bifidobacteriales 201174|Actinobacteria S 50S ribosome-binding GTPase - - - - - - - - - - - - MMR_HSR1 JIJKFJGP_01452 552531.BIF_01861 7.52e-95 276.0 2DTWH@1|root,33MZC@2|Bacteria,2GUGG@201174|Actinobacteria,4D1FM@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01453 552531.BIF_01090 0.0 962.0 COG0389@1|root,COG0389@2|Bacteria,2GQX7@201174|Actinobacteria,4CZ0D@85004|Bifidobacteriales 201174|Actinobacteria L DNA-damage repair protein (DNA polymerase IV) K00961 - - - ko:K03502 - - - - ko00000,ko03400 - - - IMS,IMS_C,IMS_HHH JIJKFJGP_01454 552531.BIF_01091 0.0 1040.0 COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4CZ89@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF GO:0008150,GO:0040007 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_6,GATase_7,Pribosyltran JIJKFJGP_01455 552531.BIF_00948 3.44e-251 690.0 COG0150@1|root,COG0150@2|Bacteria,2GJNY@201174|Actinobacteria,4CZ3K@85004|Bifidobacteriales 201174|Actinobacteria F Phosphoribosylformylglycinamidine cyclo-ligase purM GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016882,GO:0044424,GO:0044444,GO:0044464 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C JIJKFJGP_01456 552531.BIF_00947 2.74e-305 832.0 COG0151@1|root,COG0151@2|Bacteria,2I2F5@201174|Actinobacteria,4CZ3I@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the GARS family purD GO:0008150,GO:0040007 6.3.3.1,6.3.4.13 ko:K01945,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04208 RC00090,RC00166,RC01100 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N JIJKFJGP_01457 552531.BIF_00711 0.0 915.0 COG0627@1|root,COG0627@2|Bacteria,2GP6Q@201174|Actinobacteria,4CYXF@85004|Bifidobacteriales 201174|Actinobacteria S Putative esterase - - - - - - - - - - - - Esterase JIJKFJGP_01458 552531.BIF_00625 0.0 1790.0 COG2898@1|root,COG2898@2|Bacteria,2GM2C@201174|Actinobacteria,4CYW5@85004|Bifidobacteriales 201174|Actinobacteria S Uncharacterised conserved protein (DUF2156) lysX - - - - - - - - - - - DUF2156,Rhomboid JIJKFJGP_01459 552531.BIF_01182 2.4e-93 273.0 COG0735@1|root,COG0735@2|Bacteria,2IKS3@201174|Actinobacteria,4D0XG@85004|Bifidobacteriales 201174|Actinobacteria P Belongs to the Fur family fur - - ko:K03711 - - - - ko00000,ko03000 - - - FUR JIJKFJGP_01460 552531.BIF_01181 1.2e-286 781.0 COG0026@1|root,COG0026@2|Bacteria,2GJCU@201174|Actinobacteria,4CYWP@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp JIJKFJGP_01461 552531.BIF_01180 6.53e-111 320.0 COG0041@1|root,COG0041@2|Bacteria,2IFFD@201174|Actinobacteria,4CYQZ@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE GO:0008150,GO:0040007 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv3275c AIRC JIJKFJGP_01462 552531.BIF_01179 0.0 1224.0 COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria,4CZ2M@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0008661,GO:0009058,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901363,GO:1901576,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C JIJKFJGP_01464 552531.BIF_00851 6.68e-282 771.0 COG1055@1|root,COG1055@2|Bacteria,2GP6U@201174|Actinobacteria,4CZ37@85004|Bifidobacteriales 201174|Actinobacteria P Citrate transporter - - - - - - - - - - - - CitMHS JIJKFJGP_01465 552531.BIF_00286 0.0 1384.0 COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,4CYZG@85004|Bifidobacteriales 201174|Actinobacteria L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2 JIJKFJGP_01466 552531.BIF_02122 0.0 901.0 COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria,4CZ2Q@85004|Bifidobacteriales 201174|Actinobacteria M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N JIJKFJGP_01467 552531.BIF_01130 1.21e-129 368.0 COG1670@1|root,COG1670@2|Bacteria,2HBE2@201174|Actinobacteria,4CZTR@85004|Bifidobacteriales 201174|Actinobacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins cysE - - - - - - - - - - - - JIJKFJGP_01468 552531.BIF_01888 8.52e-122 347.0 COG1854@1|root,COG1854@2|Bacteria,2GJVF@201174|Actinobacteria,4CYZ4@85004|Bifidobacteriales 201174|Actinobacteria H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) luxS - 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 - - - LuxS JIJKFJGP_01469 552531.BIF_01132 3.3e-290 792.0 COG0371@1|root,COG0371@2|Bacteria,2GKWA@201174|Actinobacteria,4CZ0P@85004|Bifidobacteriales 201174|Actinobacteria C Iron-containing alcohol dehydrogenase gldA - 1.1.1.6 ko:K00005,ko:K08317 ko00561,ko00640,ko01100,map00561,map00640,map01100 - R01034,R10715,R10717 RC00029,RC00117,RC00670 ko00000,ko00001,ko01000 - - - Fe-ADH JIJKFJGP_01470 552531.BIF_00352 5.05e-190 527.0 COG3752@1|root,COG3752@2|Bacteria,2HXIT@201174|Actinobacteria,4CZVB@85004|Bifidobacteriales 201174|Actinobacteria S 3-oxo-5-alpha-steroid 4-dehydrogenase - - - - - - - - - - - - DUF1295 JIJKFJGP_01471 552531.BIF_00351 2.04e-114 327.0 COG0454@1|root,COG0456@2|Bacteria,2II91@201174|Actinobacteria,4D0SH@85004|Bifidobacteriales 201174|Actinobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 JIJKFJGP_01472 552531.BIF_01887 9.13e-119 339.0 COG3654@1|root,COG3654@2|Bacteria,2IEQI@201174|Actinobacteria,4D0S5@85004|Bifidobacteriales 201174|Actinobacteria S Fic/DOC family - - - ko:K07341 - - - - ko00000,ko02048 - - - Fic JIJKFJGP_01473 552531.BIF_01886 3.33e-123 350.0 COG3600@1|root,COG3600@2|Bacteria,2IDCY@201174|Actinobacteria,4CYZW@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF4065) - - - - - - - - - - - - DUF4065 JIJKFJGP_01474 552531.BIF_00116 0.0 1296.0 COG1479@1|root,COG1479@2|Bacteria,2I99F@201174|Actinobacteria,4D06A@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF1524) - - - - - - - - - - - - DUF1524,DUF262 JIJKFJGP_01475 552531.BIF_02121 8.48e-81 244.0 COG3177@1|root,COG3177@2|Bacteria,2GN3K@201174|Actinobacteria,4D1MZ@85004|Bifidobacteriales 201174|Actinobacteria S Fic/DOC family - - - - - - - - - - - - Fic,Fic_N JIJKFJGP_01476 552531.BIF_01310 0.0 2063.0 COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,2GJ4Y@201174|Actinobacteria,4CZNN@85004|Bifidobacteriales 201174|Actinobacteria KL Domain of unknown function (DUF3427) - - - - - - - - - - - - DUF3427,Helicase_C,PLDc_2,ResIII JIJKFJGP_01477 552531.BIF_01309 7.91e-95 278.0 COG0494@1|root,COG0494@2|Bacteria,2I2GY@201174|Actinobacteria,4D0UJ@85004|Bifidobacteriales 201174|Actinobacteria L NUDIX domain mutT - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX JIJKFJGP_01478 552531.BIF_01308 4.86e-84 248.0 29Z0K@1|root,30KXR@2|Bacteria,2ISYF@201174|Actinobacteria,4D1DX@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01479 552531.BIF_00876 3.78e-76 228.0 2B78E@1|root,320B0@2|Bacteria,2IQ9E@201174|Actinobacteria,4D1CK@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01481 552531.BIF_02120 1.14e-30 107.0 COG4283@1|root,COG4283@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1706) M1-431 - - - - - - - - - - - DUF1706 JIJKFJGP_01482 552531.BIF_00878 4.02e-52 163.0 COG4283@1|root,COG4283@2|Bacteria,2IGS2@201174|Actinobacteria,4D14I@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF1706) - - - - - - - - - - - - DUF1706 JIJKFJGP_01485 552531.BIF_01009 1.29e-135 390.0 COG1670@1|root,COG1670@2|Bacteria,2HZBU@201174|Actinobacteria,4CZN2@85004|Bifidobacteriales 201174|Actinobacteria J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 JIJKFJGP_01486 552531.BIF_01008 1.01e-221 611.0 COG2852@1|root,COG2852@2|Bacteria,2GN40@201174|Actinobacteria,4CZPZ@85004|Bifidobacteriales 201174|Actinobacteria S Protein conserved in bacteria - - - - - - - - - - - - DUF559 JIJKFJGP_01487 552531.BIF_01869 0.0 1286.0 COG0514@1|root,COG0514@2|Bacteria,2GJSS@201174|Actinobacteria,4CZ0I@85004|Bifidobacteriales 201174|Actinobacteria L ATP-dependent DNA helicase RecQ recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind JIJKFJGP_01488 552531.BIF_00615 5.12e-243 667.0 COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4CYQ4@85004|Bifidobacteriales 201174|Actinobacteria E Pyridoxal-phosphate dependent enzyme cbs GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 2.5.1.47,4.2.1.22 ko:K01697,ko:K01738 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00035,M00338 R00891,R00897,R01290,R03601,R04859,R04942 RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - CBS,PALP JIJKFJGP_01489 552531.BIF_00399 3.07e-284 776.0 COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4CYY2@85004|Bifidobacteriales 201174|Actinobacteria E Cys/Met metabolism PLP-dependent enzyme metB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1079 Cys_Met_Meta_PP JIJKFJGP_01490 552531.BIF_01418 9.13e-180 501.0 COG4608@1|root,COG4608@2|Bacteria,2GP46@201174|Actinobacteria,4CYXD@85004|Bifidobacteriales 201174|Actinobacteria E ATPases associated with a variety of cellular activities - - - ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran JIJKFJGP_01491 552531.BIF_01417 4.99e-181 504.0 COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,4D2W3@85004|Bifidobacteriales 201174|Actinobacteria P ATPases associated with a variety of cellular activities oppDF2 - - ko:K02031,ko:K02032,ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY JIJKFJGP_01492 552531.BIF_01416 8.71e-201 557.0 COG1173@1|root,COG1173@2|Bacteria,2GNQ5@201174|Actinobacteria,4CZ84@85004|Bifidobacteriales 201174|Actinobacteria EP Binding-protein-dependent transport system inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 JIJKFJGP_01493 552531.BIF_01415 7.86e-217 600.0 COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,4CYST@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 JIJKFJGP_01494 552531.BIF_02118 0.0 1149.0 COG0747@1|root,COG0747@2|Bacteria,2GJ4B@201174|Actinobacteria,4CYWF@85004|Bifidobacteriales 201174|Actinobacteria E ABC transporter, substrate-binding protein, family 5 - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 JIJKFJGP_01495 552531.BIF_01412 1.14e-175 490.0 COG1521@1|root,COG1521@2|Bacteria,2GMRQ@201174|Actinobacteria,4CZQS@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase JIJKFJGP_01496 552531.BIF_01411 6.41e-89 261.0 2B8P1@1|root,321YK@2|Bacteria,2H65M@201174|Actinobacteria,4D29M@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01497 552531.BIF_01410 2.61e-184 511.0 COG0564@1|root,COG0564@2|Bacteria,2GJ2Z@201174|Actinobacteria,4CZB2@85004|Bifidobacteriales 201174|Actinobacteria J RNA pseudouridylate synthase - - 5.4.99.28,5.4.99.29 ko:K06177 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 JIJKFJGP_01498 552531.BIF_00755 0.0 1196.0 COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria,4CZ1G@85004|Bifidobacteriales 201174|Actinobacteria M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iNJ661.Rv3436c GATase_6,SIS JIJKFJGP_01499 552531.BIF_00316 1.98e-164 459.0 COG2197@1|root,COG2197@2|Bacteria,2IQKB@201174|Actinobacteria,4D0VR@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg JIJKFJGP_01500 552531.BIF_01039 2.66e-231 636.0 COG5340@1|root,COG5340@2|Bacteria,2ICPH@201174|Actinobacteria,4CZJ7@85004|Bifidobacteriales 201174|Actinobacteria K Psort location Cytoplasmic, score - - - - - - - - - - - - - JIJKFJGP_01501 552531.BIF_01038 2.6e-197 547.0 COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4CZSB@85004|Bifidobacteriales 201174|Actinobacteria E ATPases associated with a variety of cellular activities tcyC - 3.6.3.21 ko:K02028,ko:K02029 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran JIJKFJGP_01502 552531.BIF_00580 6.2e-208 579.0 COG0765@1|root,COG0765@2|Bacteria,2GJJ9@201174|Actinobacteria,4CYSN@85004|Bifidobacteriales 201174|Actinobacteria E Binding-protein-dependent transport system inner membrane component yecS - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 JIJKFJGP_01503 552531.BIF_01811 3.75e-215 595.0 COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria,4CZ6H@85004|Bifidobacteriales 201174|Actinobacteria ET ABC transporter, substrate-binding protein, family 3 glnH - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 JIJKFJGP_01504 552531.BIF_00905 3.92e-213 592.0 COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria,4CZ6H@85004|Bifidobacteriales 201174|Actinobacteria ET ABC transporter, substrate-binding protein, family 3 glnH - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 JIJKFJGP_01505 552531.BIF_00906 1.36e-105 305.0 COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria,4CZG4@85004|Bifidobacteriales 201174|Actinobacteria J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03664 - - - - ko00000 - - - SmpB JIJKFJGP_01506 552531.BIF_00825 3.74e-282 779.0 COG3942@1|root,COG3942@2|Bacteria,2GZG8@201174|Actinobacteria,4CYQJ@85004|Bifidobacteriales 201174|Actinobacteria D CHAP domain protein - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - CHAP JIJKFJGP_01507 552531.BIF_00824 2.42e-209 580.0 COG2177@1|root,COG2177@2|Bacteria,2GJMA@201174|Actinobacteria,4CZSQ@85004|Bifidobacteriales 201174|Actinobacteria D Part of the ABC transporter FtsEX involved in cellular division ftsX GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX JIJKFJGP_01508 552531.BIF_00823 1.64e-298 816.0 COG2884@1|root,COG2884@2|Bacteria,2GJE1@201174|Actinobacteria,4CYYQ@85004|Bifidobacteriales 201174|Actinobacteria D Cell division ATP-binding protein FtsE ftsE GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran JIJKFJGP_01509 552531.BIF_00137 1.65e-265 728.0 COG1186@1|root,COG1186@2|Bacteria,2GJ0F@201174|Actinobacteria,4CZJX@85004|Bifidobacteriales 201174|Actinobacteria J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 JIJKFJGP_01510 552531.BIF_00154 1.57e-236 650.0 COG2171@1|root,COG2171@2|Bacteria,2GIZ9@201174|Actinobacteria,4CYVT@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA dapD GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1201c Hexapep_2,THDPS_M JIJKFJGP_01511 552531.BIF_01005 6.33e-109 313.0 COG1576@1|root,COG1576@2|Bacteria,2IJE0@201174|Actinobacteria,4D0P5@85004|Bifidobacteriales 201174|Actinobacteria J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH - 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase JIJKFJGP_01512 552531.BIF_01003 0.0 868.0 COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4CZ2J@85004|Bifidobacteriales 201174|Actinobacteria C Citrate synthase, C-terminal domain gltA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt JIJKFJGP_01513 35760.BCHO_0542 1.86e-165 465.0 COG0024@1|root,COG0024@2|Bacteria,2GKKB@201174|Actinobacteria,4CZAA@85004|Bifidobacteriales 201174|Actinobacteria E Methionine aminopeptidase map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 JIJKFJGP_01514 552531.BIF_01840 1.78e-133 380.0 COG3247@1|root,COG3247@2|Bacteria,2H3AT@201174|Actinobacteria,4D00R@85004|Bifidobacteriales 201174|Actinobacteria S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 JIJKFJGP_01515 552531.BIF_00205 0.0 1418.0 COG3590@1|root,COG3590@2|Bacteria,2GNJY@201174|Actinobacteria,4CYVU@85004|Bifidobacteriales 201174|Actinobacteria O Peptidase family M13 pepO - 3.4.24.11,3.4.24.71 ko:K01389,ko:K01415,ko:K07386 ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - Peptidase_M13,Peptidase_M13_N JIJKFJGP_01516 552531.BIF_00472 6.13e-174 484.0 COG0629@1|root,COG0629@2|Bacteria,2IPBU@201174|Actinobacteria,4D2T5@85004|Bifidobacteriales 201174|Actinobacteria L Single-strand binding protein family - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB JIJKFJGP_01517 552531.BIF_00473 0.0 1211.0 COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,4CZ6E@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit JIJKFJGP_01518 552531.BIF_00757 7.39e-98 284.0 2A4HC@1|root,30T3N@2|Bacteria,2IM9N@201174|Actinobacteria,4D0VS@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01519 552531.BIF_00756 0.0 956.0 COG0507@1|root,COG0507@2|Bacteria,2HFY1@201174|Actinobacteria,4CZ0C@85004|Bifidobacteriales 201174|Actinobacteria L PIF1-like helicase - - - - - - - - - - - - PIF1 JIJKFJGP_01520 552531.BIF_00589 1.72e-200 556.0 COG0561@1|root,COG0561@2|Bacteria,2HZBZ@201174|Actinobacteria,4CZNM@85004|Bifidobacteriales 201174|Actinobacteria S Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 JIJKFJGP_01521 552531.BIF_00588 1.09e-158 445.0 COG1949@1|root,COG1949@2|Bacteria,2GJR7@201174|Actinobacteria,4CYZY@85004|Bifidobacteriales 201174|Actinobacteria L 3'-to-5' exoribonuclease specific for small oligoribonucleotides orn GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360 - ko:K13288 ko03008,map03008 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - RNase_T JIJKFJGP_01522 552531.BIF_00769 0.0 997.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2GITZ@201174|Actinobacteria,4CZ2S@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006183,GO:0006195,GO:0006204,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009125,GO:0009126,GO:0009127,GO:0009128,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009154,GO:0009156,GO:0009158,GO:0009161,GO:0009163,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009169,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009261,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046037,GO:0046039,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH JIJKFJGP_01523 552531.BIF_00770 1.04e-268 736.0 COG0472@1|root,COG0472@2|Bacteria,2GIT7@201174|Actinobacteria,4CZ4P@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyl transferase family 4 rfe GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 ko:K02851 - - R08856 RC00002 ko00000,ko01000,ko01003,ko01005 - - - Glycos_transf_4 JIJKFJGP_01524 552531.BIF_00602 2.61e-150 424.0 COG0009@1|root,COG0009@2|Bacteria,2GK2X@201174|Actinobacteria,4CYVA@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the SUA5 family ywlC GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - Sua5_yciO_yrdC JIJKFJGP_01525 552531.BIF_00601 9.47e-225 619.0 COG2890@1|root,COG2890@2|Bacteria,2GMH1@201174|Actinobacteria,4CZB3@85004|Bifidobacteriales 201174|Actinobacteria J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS,Methyltransf_25,Methyltransf_31 JIJKFJGP_01526 398513.BBNG_01695 9.55e-217 603.0 COG0216@1|root,COG0216@2|Bacteria,2GJWG@201174|Actinobacteria,4CYX4@85004|Bifidobacteriales 201174|Actinobacteria J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA GO:0008150,GO:0040007 - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 JIJKFJGP_01527 552531.BIF_00831 4e-21 83.6 COG0254@1|root,COG0254@2|Bacteria,2IQ4I@201174|Actinobacteria,4D17F@85004|Bifidobacteriales 201174|Actinobacteria J Binds the 23S rRNA rpmE GO:0008150,GO:0040007 - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 JIJKFJGP_01529 552531.BIF_00469 1.14e-145 420.0 COG1653@1|root,COG1653@2|Bacteria,2GWCY@201174|Actinobacteria,4CYWG@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein amyE - - ko:K10117 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - SBP_bac_8 JIJKFJGP_01531 552531.BIF_00745 4.41e-232 642.0 COG1609@1|root,COG1609@2|Bacteria,2GJBJ@201174|Actinobacteria,4CZ1Y@85004|Bifidobacteriales 201174|Actinobacteria K Psort location Cytoplasmic, score - - - - - - - - - - - - LacI,Peripla_BP_3 JIJKFJGP_01532 552531.BIF_00746 1.1e-199 554.0 COG1175@1|root,COG1175@2|Bacteria,2I330@201174|Actinobacteria,4CZJC@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component msmF - - ko:K10118 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 JIJKFJGP_01533 552531.BIF_00747 1.7e-197 547.0 COG0395@1|root,COG0395@2|Bacteria,2GJNN@201174|Actinobacteria,4CYZ9@85004|Bifidobacteriales 201174|Actinobacteria G ABC transporter permease - - - ko:K02026,ko:K10119 ko02010,map02010 M00196,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.28 - - BPD_transp_1 JIJKFJGP_01534 552531.BIF_00870 3.35e-140 396.0 COG5578@1|root,COG5578@2|Bacteria,2IBKF@201174|Actinobacteria,4D0E0@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function, DUF624 - - - - - - - - - - - - DUF624 JIJKFJGP_01535 552531.BIF_00869 0.0 1485.0 COG1640@1|root,COG1640@2|Bacteria,2GM5Z@201174|Actinobacteria,4CZ0F@85004|Bifidobacteriales 201174|Actinobacteria G 4-alpha-glucanotransferase malQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 JIJKFJGP_01536 552531.BIF_01621 0.0 1120.0 COG0366@1|root,COG0366@2|Bacteria,2GIV1@201174|Actinobacteria,4CZ7N@85004|Bifidobacteriales 201174|Actinobacteria G Alpha-amylase domain malL - 2.4.1.4,3.2.1.1,3.2.1.20,5.4.99.16 ko:K01187,ko:K05341,ko:K05343 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R01557,R01823,R02108,R02112,R06087,R06088,R11262 RC00028,RC00049,RC00077,RC01816 ko00000,ko00001,ko01000 - GH13,GH31 - Alpha-amylase,DUF3459 JIJKFJGP_01537 552531.BIF_01620 5.8e-303 827.0 COG2182@1|root,COG2182@2|Bacteria,2GJ8S@201174|Actinobacteria,4CZ8G@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein malE - - ko:K15770 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - SBP_bac_1,SBP_bac_8 JIJKFJGP_01538 552531.BIF_01619 0.0 933.0 COG1175@1|root,COG1175@2|Bacteria,2GJGB@201174|Actinobacteria,4CYZ8@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component malC - - ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 JIJKFJGP_01539 552531.BIF_01618 2.29e-226 624.0 COG3833@1|root,COG3833@2|Bacteria,2I2EZ@201174|Actinobacteria,4CZDE@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component malG - - ko:K15772 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 JIJKFJGP_01540 552531.BIF_01617 0.0 1442.0 COG1523@1|root,COG1523@2|Bacteria,2I2GM@201174|Actinobacteria,4CYSS@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 13 family apuB - 3.2.1.41,3.2.1.68 ko:K01200,ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02111,R09995,R11261 - ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48,CW_binding_1,DUF3372,PUD JIJKFJGP_01541 552531.BIF_01616 1.55e-190 528.0 COG1011@1|root,COG1011@2|Bacteria,2I2GN@201174|Actinobacteria,4CZF4@85004|Bifidobacteriales 201174|Actinobacteria S HAD-hyrolase-like - - - ko:K07025 - - - - ko00000 - - - HAD_2,Hydrolase JIJKFJGP_01542 552531.BIF_01931 8.73e-187 518.0 2AYHW@1|root,32WBP@2|Bacteria,2I9DQ@201174|Actinobacteria,4CYRI@85004|Bifidobacteriales 201174|Actinobacteria S TraX protein traX - - - - - - - - - - - TraX JIJKFJGP_01543 552531.BIF_01615 4.59e-247 678.0 COG1609@1|root,COG1609@2|Bacteria,2GJBJ@201174|Actinobacteria,4CZ1Y@85004|Bifidobacteriales 201174|Actinobacteria K Psort location Cytoplasmic, score - - - - - - - - - - - - LacI,Peripla_BP_3 JIJKFJGP_01545 552531.BIF_01614 0.0 1154.0 COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria,4CZDX@85004|Bifidobacteriales 201174|Actinobacteria O Heat shock 70 kDa protein dnaK GO:0000302,GO:0000303,GO:0000305,GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016310,GO:0019222,GO:0019538,GO:0019899,GO:0030112,GO:0030162,GO:0030312,GO:0030313,GO:0031323,GO:0031325,GO:0031975,GO:0031982,GO:0032268,GO:0032270,GO:0033554,GO:0034599,GO:0034614,GO:0035375,GO:0036211,GO:0040007,GO:0042221,GO:0042603,GO:0043170,GO:0043226,GO:0043227,GO:0043230,GO:0043388,GO:0043412,GO:0044044,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046677,GO:0046688,GO:0046777,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051099,GO:0051101,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070613,GO:0070887,GO:0071450,GO:0071451,GO:0071704,GO:0071944,GO:0080090,GO:0097691,GO:1901564,GO:1901700,GO:1901701,GO:1903317,GO:1903319,GO:1903561,GO:2000677,GO:2000679 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 JIJKFJGP_01546 552531.BIF_01612 6.25e-132 377.0 COG0576@1|root,COG0576@2|Bacteria,2GP4F@201174|Actinobacteria,4CZJ6@85004|Bifidobacteriales 201174|Actinobacteria O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE JIJKFJGP_01547 552531.BIF_01611 4.87e-238 656.0 COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4CZ68@85004|Bifidobacteriales 201174|Actinobacteria O DnaJ molecular chaperone homology domain dnaJ GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679 - ko:K03686,ko:K05516 - - - - ko00000,ko03029,ko03036,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG JIJKFJGP_01548 552531.BIF_01610 1.43e-119 342.0 COG0789@1|root,COG0789@2|Bacteria,2IQJ4@201174|Actinobacteria,4D0Q7@85004|Bifidobacteriales 201174|Actinobacteria K transcriptional regulator, MerR family hspR GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K13640 - - - - ko00000,ko03000 - - - MerR_1 JIJKFJGP_01549 552531.BIF_01609 1.2e-166 466.0 COG0637@1|root,COG0637@2|Bacteria,2GJNG@201174|Actinobacteria,4CYZV@85004|Bifidobacteriales 201174|Actinobacteria S HAD hydrolase, family IA, variant 3 - - - - - - - - - - - - HAD_2 JIJKFJGP_01550 552531.BIF_01608 4.71e-146 412.0 COG1309@1|root,COG1309@2|Bacteria,2I8DN@201174|Actinobacteria,4D0GB@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_C_6,TetR_N JIJKFJGP_01551 552531.BIF_01607 0.0 1553.0 COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4CZT6@85004|Bifidobacteriales 201174|Actinobacteria G Fibronectin type III-like domain bgl2 - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C JIJKFJGP_01552 552531.BIF_00699 6.19e-163 456.0 COG4832@1|root,COG4832@2|Bacteria,2GN4K@201174|Actinobacteria,4D08M@85004|Bifidobacteriales 201174|Actinobacteria S GyrI-like small molecule binding domain - - - - - - - - - - - - GyrI-like JIJKFJGP_01554 552531.BIF_00927 2.12e-174 486.0 COG0586@1|root,COG0586@2|Bacteria,2GKGR@201174|Actinobacteria,4CZ7Y@85004|Bifidobacteriales 201174|Actinobacteria S SNARE associated Golgi protein dedA1 - - ko:K03975 - - - - ko00000 - - - SNARE_assoc JIJKFJGP_01555 552531.BIF_00928 1.2e-201 557.0 COG0657@1|root,COG0657@2|Bacteria,2HZCA@201174|Actinobacteria,4CZQE@85004|Bifidobacteriales 201174|Actinobacteria I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3,Peptidase_S9 JIJKFJGP_01556 552531.BIF_00930 0.0 1100.0 COG1928@1|root,COG1928@2|Bacteria,2I2H1@201174|Actinobacteria,4CZGF@85004|Bifidobacteriales 201174|Actinobacteria O C-terminal four TMM region of protein-O-mannosyltransferase pmt - 2.4.1.109 ko:K00728 ko00514,ko00515,ko01100,map00514,map00515,map01100 - R04072,R07620,R11399 RC00005,RC00059,RC00397 ko00000,ko00001,ko01000,ko01003 - GT39 - PMT,PMT_4TMC JIJKFJGP_01557 552531.BIF_01084 3.49e-221 613.0 COG0313@1|root,COG0313@2|Bacteria,2GJ9Q@201174|Actinobacteria,4CZ03@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase JIJKFJGP_01558 552531.BIF_01085 9.93e-94 274.0 2B10P@1|root,31TDZ@2|Bacteria,2GS86@201174|Actinobacteria,4D1GZ@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01559 552531.BIF_01430 2.01e-167 468.0 2AU2N@1|root,31JNZ@2|Bacteria,2IJNI@201174|Actinobacteria,4D047@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01560 35760.BCHO_1290 0.0 1140.0 COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,4CZ20@85004|Bifidobacteriales 201174|Actinobacteria J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g JIJKFJGP_01561 552531.BIF_02195 0.0 1185.0 COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4D028@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran JIJKFJGP_01562 552531.BIF_00887 0.0 1111.0 COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CZ32@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran JIJKFJGP_01563 552531.BIF_01623 6.89e-166 467.0 2AU3T@1|root,31JQA@2|Bacteria,2IJQ7@201174|Actinobacteria,4D0VX@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01564 552531.BIF_01624 0.0 1657.0 COG3345@1|root,COG3345@2|Bacteria,2GJJ1@201174|Actinobacteria,4CZDM@85004|Bifidobacteriales 201174|Actinobacteria G Psort location Cytoplasmic, score 8.87 - - 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Glyco_hydro_36N,Melibiase JIJKFJGP_01565 552531.BIF_01625 1.7e-235 647.0 COG0084@1|root,COG0084@2|Bacteria,2GMJJ@201174|Actinobacteria,4CYZI@85004|Bifidobacteriales 201174|Actinobacteria L TatD related DNase tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase JIJKFJGP_01566 552531.BIF_01626 0.0 1429.0 COG3158@1|root,COG3158@2|Bacteria,2GMPQ@201174|Actinobacteria,4CZM3@85004|Bifidobacteriales 201174|Actinobacteria P Transport of potassium into the cell kup - - ko:K03549 - - - - ko00000,ko02000 2.A.72 - - K_trans JIJKFJGP_01567 552531.BIF_01627 1.17e-217 600.0 COG0121@1|root,COG0121@2|Bacteria,2IBFV@201174|Actinobacteria,4CYX2@85004|Bifidobacteriales 201174|Actinobacteria S Glutamine amidotransferase domain - - - - - - - - - - - - GATase_6 JIJKFJGP_01568 552531.BIF_01628 8.09e-195 539.0 COG2206@1|root,COG2206@2|Bacteria,2GNQR@201174|Actinobacteria,4CYT9@85004|Bifidobacteriales 201174|Actinobacteria T HD domain - - - ko:K06950 - - - - ko00000 - - - HD JIJKFJGP_01569 552531.BIF_01629 4.6e-249 684.0 COG1136@1|root,COG1136@2|Bacteria,2GNFW@201174|Actinobacteria,4CZAW@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran JIJKFJGP_01570 552531.BIF_01630 0.0 872.0 COG0577@1|root,COG0577@2|Bacteria,2GMGJ@201174|Actinobacteria,4CZBN@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter permease - - - - - - - - - - - - FtsX,MacB_PCD JIJKFJGP_01571 552531.BIF_01645 0.0 1087.0 2ANBU@1|root,31DA7@2|Bacteria,2IAHJ@201174|Actinobacteria,4CYW4@85004|Bifidobacteriales 201174|Actinobacteria S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - - JIJKFJGP_01572 552531.BIF_01643 0.0 1521.0 COG1807@1|root,COG1807@2|Bacteria,2GNXR@201174|Actinobacteria,4CYRK@85004|Bifidobacteriales 201174|Actinobacteria M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - - JIJKFJGP_01573 552531.BIF_01642 0.0 1508.0 COG1807@1|root,COG1807@2|Bacteria,2GNXR@201174|Actinobacteria,4CYRK@85004|Bifidobacteriales 201174|Actinobacteria M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - - JIJKFJGP_01575 552531.BIF_01641 0.0 1313.0 COG1216@1|root,COG1216@2|Bacteria,2GNJN@201174|Actinobacteria,4CZ2V@85004|Bifidobacteriales 201174|Actinobacteria S Glycosyltransferase like family 2 - - - - - - - - - - - - Glyco_tranf_2_3 JIJKFJGP_01576 552531.BIF_01640 5.64e-194 538.0 COG1682@1|root,COG1682@2|Bacteria,2GP5K@201174|Actinobacteria,4CZ73@85004|Bifidobacteriales 201174|Actinobacteria U Transport permease protein tagG - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane JIJKFJGP_01577 552531.BIF_01639 0.0 932.0 COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria,4CZ1B@85004|Bifidobacteriales 201174|Actinobacteria GM ABC transporter, ATP-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,Wzt_C JIJKFJGP_01578 552531.BIF_01638 0.0 910.0 COG2327@1|root,COG2327@2|Bacteria,2H0DT@201174|Actinobacteria,4D0FB@85004|Bifidobacteriales 201174|Actinobacteria S Polysaccharide pyruvyl transferase - - - - - - - - - - - - PS_pyruv_trans JIJKFJGP_01579 552531.BIF_01637 1.2e-172 481.0 2C89M@1|root,332IE@2|Bacteria,2IPVJ@201174|Actinobacteria,4D133@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01580 552531.BIF_01636 3.31e-130 369.0 COG3757@1|root,COG3757@2|Bacteria,2I42D@201174|Actinobacteria,4D07U@85004|Bifidobacteriales 201174|Actinobacteria M hydrolase, family 25 - - - - - - - - - - - - Big_2,Flg_new,SLH JIJKFJGP_01581 552531.BIF_01635 1.62e-78 239.0 COG4886@1|root,COG4886@2|Bacteria,2H1CZ@201174|Actinobacteria,4D1S8@85004|Bifidobacteriales 201174|Actinobacteria S Leucine-rich repeat (LRR) protein - - - - - - - - - - - - - JIJKFJGP_01582 552531.BIF_01634 2.61e-239 655.0 COG3677@1|root,COG3677@2|Bacteria,2IEJD@201174|Actinobacteria,4CZ5C@85004|Bifidobacteriales 201174|Actinobacteria L Transposase and inactivated derivatives tnp3503b - - - - - - - - - - - Transposase_mut JIJKFJGP_01583 552531.BIF_01633 0.0 1098.0 COG3391@1|root,COG3757@1|root,COG3391@2|Bacteria,COG3757@2|Bacteria,2I2GQ@201174|Actinobacteria,4D08Z@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyl hydrolases family 25 - - - - - - - - - - - - Glyco_hydro_25,RicinB_lectin_2,SLH JIJKFJGP_01584 552531.BIF_01632 2.57e-226 621.0 COG3757@1|root,COG3757@2|Bacteria,2I2GQ@201174|Actinobacteria,4D08Z@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyl hydrolases family 25 - - - - - - - - - - - - Glyco_hydro_25,RicinB_lectin_2,SLH JIJKFJGP_01585 552531.BIF_01252 0.0 1424.0 COG1216@1|root,COG1216@2|Bacteria,2GM9N@201174|Actinobacteria,4CZ30@85004|Bifidobacteriales 201174|Actinobacteria S Glycosyltransferase like family 2 glfT GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0006139,GO:0006629,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008378,GO:0008610,GO:0008653,GO:0008921,GO:0009058,GO:0009059,GO:0009103,GO:0009225,GO:0009273,GO:0009987,GO:0010383,GO:0016020,GO:0016043,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0022607,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0035250,GO:0035496,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045229,GO:0046483,GO:0052573,GO:0055086,GO:0070589,GO:0070592,GO:0071554,GO:0071555,GO:0071704,GO:0071766,GO:0071769,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901576,GO:1903509 2.4.1.288 ko:K16650 - - - - ko00000,ko01000,ko01003 - GT2 iNJ661.Rv3808c Glyco_tranf_2_3 JIJKFJGP_01586 552531.BIF_01251 0.0 1531.0 COG1368@1|root,COG1368@2|Bacteria,2HVID@201174|Actinobacteria,4CZ6J@85004|Bifidobacteriales 201174|Actinobacteria M Psort location CytoplasmicMembrane, score 9.26 - - - - - - - - - - - - Sulfatase JIJKFJGP_01587 552531.BIF_01490 0.0 1398.0 COG1368@1|root,COG1368@2|Bacteria,2HVID@201174|Actinobacteria,4CZ6J@85004|Bifidobacteriales 201174|Actinobacteria M Psort location CytoplasmicMembrane, score 9.26 - - - - - - - - - - - - Sulfatase JIJKFJGP_01588 552531.BIF_01491 3.65e-253 693.0 COG1216@1|root,COG1216@2|Bacteria,2GMQQ@201174|Actinobacteria,4CZRJ@85004|Bifidobacteriales 201174|Actinobacteria S Glycosyltransferase, group 2 family protein - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 JIJKFJGP_01590 552531.BIF_01492 2.34e-266 728.0 COG1215@1|root,COG1215@2|Bacteria,2IBNW@201174|Actinobacteria,4CZXT@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyl transferase family 2 amsE - - - - - - - - - - - Glycos_transf_2 JIJKFJGP_01591 552531.BIF_02191 1.05e-299 816.0 COG0562@1|root,COG0562@2|Bacteria,2GK2Z@201174|Actinobacteria,4CZ2W@85004|Bifidobacteriales 201174|Actinobacteria M UDP-galactopyranose mutase glf GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071840,GO:0071944 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 - R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 - - iNJ661.Rv3809c GLF,NAD_binding_8 JIJKFJGP_01592 566461.SSFG_05975 8.79e-10 60.1 2E4EA@1|root,3068J@2|Bacteria,2GZWZ@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01593 552531.BIF_01549 0.0 939.0 COG2211@1|root,COG2211@2|Bacteria,2HD4Y@201174|Actinobacteria,4CZRA@85004|Bifidobacteriales 201174|Actinobacteria G Psort location CytoplasmicMembrane, score 10.00 - - - ko:K03292 - - - - ko00000 2.A.2 - - MFS_2 JIJKFJGP_01594 552531.BIF_01548 0.0 1378.0 COG3533@1|root,COG3533@2|Bacteria,2GM60@201174|Actinobacteria,4CYSU@85004|Bifidobacteriales 201174|Actinobacteria S Beta-L-arabinofuranosidase, GH127 - - 3.2.1.185 ko:K09955,ko:K18205 - - - - ko00000,ko01000 - GH127 - Glyco_hydro_127 JIJKFJGP_01595 552531.BIF_01547 2.59e-257 704.0 COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria,4CZND@85004|Bifidobacteriales 201174|Actinobacteria K Periplasmic binding protein domain - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 JIJKFJGP_01596 552531.BIF_01546 2.72e-187 519.0 COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,4CYUW@85004|Bifidobacteriales 201174|Actinobacteria K Sir2 family cobB2 - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 JIJKFJGP_01597 552531.BIF_01598 1.43e-284 779.0 COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4CYW0@85004|Bifidobacteriales 201174|Actinobacteria E Pyridoxal-phosphate dependent enzyme ilvA GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0016020,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901605 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1559 PALP,Thr_dehydrat_C JIJKFJGP_01598 552531.BIF_01597 0.0 1268.0 COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,4CZT7@85004|Bifidobacteriales 201174|Actinobacteria G Alpha amylase, catalytic domain protein - - 3.2.1.10 ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459,Malt_amylase_C JIJKFJGP_01600 552531.BIF_01596 2.78e-237 652.0 COG5340@1|root,COG5340@2|Bacteria,2IDUY@201174|Actinobacteria,4D00E@85004|Bifidobacteriales 201174|Actinobacteria K Psort location Cytoplasmic, score - - - - - - - - - - - - - JIJKFJGP_01601 552531.BIF_01595 0.0 1337.0 COG3345@1|root,COG3345@2|Bacteria,2GKZ2@201174|Actinobacteria,4CYZ3@85004|Bifidobacteriales 201174|Actinobacteria G Raffinose synthase or seed imbibition protein Sip1 - - - - - - - - - - - - Raffinose_syn JIJKFJGP_01602 552531.BIF_01594 3.43e-206 571.0 COG0395@1|root,COG0395@2|Bacteria,2GNQW@201174|Actinobacteria,4D02Q@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K10119 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 JIJKFJGP_01603 552531.BIF_01593 1.35e-238 655.0 COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4CZPG@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K10118 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 JIJKFJGP_01604 552531.BIF_01592 1.66e-308 841.0 COG1653@1|root,COG1653@2|Bacteria,2GN9T@201174|Actinobacteria,4CZ4V@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K10117 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - SBP_bac_1,SBP_bac_8 JIJKFJGP_01605 552531.BIF_00628 2.57e-297 810.0 COG1846@1|root,COG1940@1|root,COG1846@2|Bacteria,COG1940@2|Bacteria,2GMBH@201174|Actinobacteria,4CZK4@85004|Bifidobacteriales 201174|Actinobacteria GK ROK family - - - - - - - - - - - - ROK JIJKFJGP_01606 552531.BIF_00525 0.0 1516.0 COG3345@1|root,COG3345@2|Bacteria,2GJJ1@201174|Actinobacteria,4CZJB@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 36 N-terminal domain - - 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Glyco_hydro_36C,Glyco_hydro_36N,Melibiase JIJKFJGP_01607 552531.BIF_01481 4.78e-110 318.0 COG0590@1|root,COG0590@2|Bacteria,2IM3Z@201174|Actinobacteria,4D0V0@85004|Bifidobacteriales 201174|Actinobacteria FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA - 3.5.4.1,3.5.4.33 ko:K01485,ko:K11991 ko00240,ko00330,ko01100,map00240,map00330,map01100 - R00974,R01411,R02922,R10223 RC00074,RC00477,RC00514,RC00809 ko00000,ko00001,ko01000,ko03016 - - - MafB19-deam,dCMP_cyt_deam_1 JIJKFJGP_01608 552531.BIF_01482 0.0 1287.0 COG0025@1|root,COG0025@2|Bacteria,2GIUT@201174|Actinobacteria,4CZC4@85004|Bifidobacteriales 201174|Actinobacteria P Sodium/hydrogen exchanger family nhaP - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger JIJKFJGP_01609 552531.BIF_01483 3.82e-232 638.0 COG0400@1|root,COG0400@2|Bacteria,2I5NR@201174|Actinobacteria,4CZJQ@85004|Bifidobacteriales 201174|Actinobacteria S Phospholipase/Carboxylesterase - - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2 JIJKFJGP_01610 552531.BIF_00942 2.47e-253 709.0 COG1196@1|root,COG1196@2|Bacteria,2I6Y3@201174|Actinobacteria,4D2YP@85004|Bifidobacteriales 201174|Actinobacteria D nuclear chromosome segregation - - - - - - - - - - - - - JIJKFJGP_01611 552531.BIF_00943 5.78e-143 405.0 COG0717@1|root,COG0717@2|Bacteria,2GKQQ@201174|Actinobacteria,4CZEB@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the dCTP deaminase family dcd GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - - DCD JIJKFJGP_01612 552531.BIF_00250 0.0 1884.0 COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4CZ1I@85004|Bifidobacteriales 201174|Actinobacteria P Cation transporter/ATPase, N-terminus pacL2 - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 JIJKFJGP_01613 552531.BIF_01240 3.62e-223 617.0 COG0566@1|root,COG0566@2|Bacteria,2GJMR@201174|Actinobacteria,4CZB1@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family rlmB GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind JIJKFJGP_01614 552531.BIF_01046 0.0 968.0 COG0515@1|root,COG0515@2|Bacteria,2I2F0@201174|Actinobacteria,4CZ2E@85004|Bifidobacteriales 201174|Actinobacteria KLT Domain of unknown function (DUF4032) - - - - - - - - - - - - DUF4032,Kdo JIJKFJGP_01615 552531.BIF_01681 6.27e-270 739.0 COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CYU6@85004|Bifidobacteriales 201174|Actinobacteria E Belongs to the ABC transporter superfamily ugpC - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE,TOBE_2 JIJKFJGP_01616 552531.BIF_01680 1.41e-241 666.0 COG1226@1|root,COG1226@2|Bacteria,2GKNF@201174|Actinobacteria,4CZUV@85004|Bifidobacteriales 201174|Actinobacteria U Ion channel - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans_2 JIJKFJGP_01617 552531.BIF_01679 0.0 1391.0 COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4CYQG@85004|Bifidobacteriales 201174|Actinobacteria KLT Protein tyrosine kinase - - - - - - - - - - - - Pkinase JIJKFJGP_01618 1692.BMAGN_1513 3.47e-114 341.0 COG1651@1|root,COG1651@2|Bacteria,2GN3N@201174|Actinobacteria,4CZBD@85004|Bifidobacteriales 201174|Actinobacteria O Thioredoxin - - - - - - - - - - - - Thioredoxin_4 JIJKFJGP_01620 552531.BIF_01677 7.02e-285 789.0 COG3583@1|root,COG3583@2|Bacteria,2H4RU@201174|Actinobacteria,4CYY0@85004|Bifidobacteriales 201174|Actinobacteria S G5 rpfB GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0009893,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019222,GO:0022611,GO:0032502,GO:0040008,GO:0040009,GO:0040010,GO:0044111,GO:0044114,GO:0044115,GO:0044403,GO:0044419,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0051704,GO:0060255,GO:0065007,GO:0085016 - ko:K21688 - - - - ko00000 - - - DUF348,G5,Transglycosylas JIJKFJGP_01621 552531.BIF_01676 1.13e-208 578.0 COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,4CYS9@85004|Bifidobacteriales 201174|Actinobacteria J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD JIJKFJGP_01622 552531.BIF_01675 1.44e-227 627.0 COG1947@1|root,COG1947@2|Bacteria,2GKXD@201174|Actinobacteria,4CZMW@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N JIJKFJGP_01623 552531.BIF_01674 1.51e-145 410.0 2E1BJ@1|root,32WRF@2|Bacteria,2IKG0@201174|Actinobacteria,4D0S1@85004|Bifidobacteriales 201174|Actinobacteria S LytR cell envelope-related transcriptional attenuator - - - - - - - - - - - - LytR_C JIJKFJGP_01624 552531.BIF_01673 0.0 1052.0 COG0617@1|root,COG0617@2|Bacteria,2GMT1@201174|Actinobacteria,4CYUH@85004|Bifidobacteriales 201174|Actinobacteria J Probable RNA and SrmB- binding site of polymerase A pcnA - 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 - - - HD,PolyA_pol,PolyA_pol_RNAbd JIJKFJGP_01625 552531.BIF_01672 1.51e-239 659.0 COG0494@1|root,COG0494@2|Bacteria,2GWEB@201174|Actinobacteria,4CZAV@85004|Bifidobacteriales 201174|Actinobacteria L Belongs to the Nudix hydrolase family mutT4 - - - - - - - - - - - NUDIX JIJKFJGP_01626 552531.BIF_01671 0.0 1449.0 2CETP@1|root,33P5Y@2|Bacteria,2GMJ0@201174|Actinobacteria,4CZCV@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - JIJKFJGP_01627 552531.BIF_01669 0.0 2488.0 COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4CZ8M@85004|Bifidobacteriales 201174|Actinobacteria KLT MviN-like protein mviN GO:0003674,GO:0005215,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN JIJKFJGP_01628 552531.BIF_02198 2.29e-228 629.0 COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,4CYU9@85004|Bifidobacteriales 201174|Actinobacteria C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 JIJKFJGP_01629 552531.BIF_00741 0.0 867.0 COG1475@1|root,COG1475@2|Bacteria,2GNRN@201174|Actinobacteria,4CYUE@85004|Bifidobacteriales 201174|Actinobacteria K Belongs to the ParB family parB GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944 - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc JIJKFJGP_01630 552531.BIF_00740 2.2e-225 622.0 COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,4CZ2D@85004|Bifidobacteriales 201174|Actinobacteria D CobQ CobB MinD ParA nucleotide binding domain protein parA - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 JIJKFJGP_01631 552531.BIF_00658 1.82e-174 486.0 COG0357@1|root,COG0357@2|Bacteria,2GM9Z@201174|Actinobacteria,4CZ29@85004|Bifidobacteriales 201174|Actinobacteria J Specifically methylates the N7 position of a guanine in 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB ## 1511 queries scanned ## Total time (seconds): 2.0652732849121094 ## Rate: 731.62 q/s