LOCUS       c00005_gnlPro..        15696 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EFMKPOCG_5.
ACCESSION   c00005_gnlPro..
VERSION     c00005_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 08:12:37
            Original ID  :: gnl|Prokka|EFMKPOCG_5
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15696
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15696
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2579:5696]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2580..5696
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15696
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15696
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             490..1005
                     /locus_tag="ctg5_1"
                     /transl_table=11
                     /translation="MLAWLPFFLISLMFIVLLYACARSARTNIQRFKQLSLIAFLWVLT
                     AFCYTPTSYNFGTQLVIQYIQWGPVKLNVIPFQQLDIEFWLNVLLTVPLGGLLAWNFPD
                     LPWRRFIWLGFLTGLTLELGQFILDWLVNLKRWVDIDDVITNWAGVIIGAAGYKIARHV
                     PGLRWLQK"
     CDS             complement(1173..2162)
                     /locus_tag="ctg5_2"
                     /transl_table=11
                     /translation="MRMLEQIEQYIDSCIEAGDIYGASFSLITPKGINQYYHGKQGRDE
                     FAVGLDPAMIYDLASVTKVVGTTTRIFQLLSDHTIHLTDSVARSLPGFTHPEITIKNLL
                     LHNSGLPADIDNLDKMQREDLIKAVYDAPLVTAPGTTYVYSDLGFILLGWIIRAVDGSL
                     ARSIQDHVCYPLAMTNTGYNLNRPKIRFVPTEFDPRRGQIQGQVHDYKAFLLNGESGHA
                     GLFSTLTDLSVFIEMMLNFGEYQGKRVLDENVFDWLGEYDENGRTLGWERRAGRHQYFH
                     TGFTGPAVAFDLDRQIGLVVLTNRVYPTSDNQVWNQDRKRVFDLFFES"
     CDS             2580..4838
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_3"
                     /sec_met_domain="Gly_radical (E-value: 2.4e-39, bitscore:
                     126.9, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 4e-246, bitscore:
                     810.7, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITSEKTTKPAAWKGFKGGHWQEEINIRDFIQNNFTQYNGDESFL
                     AGPTAATKTLNDKVLELKKQERAAGGVLDADTKVVATITSHGPGYIQKDLEKIVGLQTD
                     KPLKRAFMPFGGIRMADDALKSYGYTPDEENDKIFTEYRKTHNQGVFDVYTPDMRKARH
                     YKIITGLPDAYARGRLIPDLPRVAVYGIDRLMEDKANDFAHIGDGELTDDVIRLREEVQ
                     DQYRALADMKKMAASYGYDISKPATNAQEAIQWMYFAYLAAIKTQNGAAMSVGRIDTTM
                     DIFIQRDLDNGVLDESQAQELIDQFVMKLRMVRFIRTEEYNSLFSGDPIWATLSMCGLG
                     VDGQHHVTKTAFRILKTLDNMGAAPEPNITILWSDRLPEDFKRYATEVSIDSSTIQYEN
                     DDLMRVQWGTDYYGIACCVSAQPIADGIQYFGARANLAKAILYAINGGRDEIAGDQVGP
                     AYEPITSEYIDYDEFMKKLDKQMDWLADTYVNSLNAIHYMHDKYYYEAAQLALKNTDLD
                     RTFATGISGLSHAADSISAIKYGHVKVIRDERGIAVDFKADNDYPRYGNNDDRADDIAK
                     WLVKELYSKMNTHHLYRNAKLSTSVLTITSNVVYGKNTGTTPNGRQKGEPFSPGANPAY
                     GAEKSGALASLLSTAKLPYRYATDGISNTFGVTPNTLGHDLESRKDTLVNMLDGYMKND
                     GMHLNINVFNKDTLIDAQKHPEEYPTLTVRVSGYCVYFADLTKEQQDDVISRTFFESM"
     CDS             4875..5696
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74; E-value:
                     4.8e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_4"
                     /sec_met_domain="Radical_SAM (E-value: 3.9e-27, bitscore:
                     88.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKQVSTTQAAAKEPLIGYVHSIETFGSVDGPGIRYVAFLQGCH
                     MRCQYCHNPDTWKLNVGDQMTADEILEDAAKYRAFWGKTGGITVSGGESLVQIDFILDL
                     FEKAKAMNISTCLDTSGQPFTREQPFFDKFERLMKVTDISLVDIKHIDSAKHKQLTQYG
                     NENILDMIQYMAQHHDDMWIRHVLVPQRTDYDEDLKKLGDYIAKIPNDVVQKVEVLPYH
                     TLGVKKYHEMKIKYRLEGIESPTQDRVANAEKLLHTADYNGYKTWMPLPKL"
     CDS             complement(5921..6232)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FeS_assembly_P"
                     /gene_functions="other (smcogs) SMCOG1048:Iron-sulfur
                     cluster assembly protein (Score: 67.1; E-value: 3.9e-21)"
                     /gene_kind="other"
                     /locus_tag="ctg5_5"
                     /sec_met_domain="FeS_assembly_P (E-value: 6.4e-21,
                     bitscore: 67.1, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTFKDRAFEALGHVIDPELGIDLVNLGLIYDAQLTAEGTAEIT
                     MTLTIAGCPLTEWLAKDIHDELIKLPEVNNIEIEIVWEPAWNESMMSREARMELGIHS"
     CDS             7293..8213
                     /locus_tag="ctg5_6"
                     /transl_table=11
                     /translation="LKTINLGHSNIQASSVALGIMRMDALDVAQATKVIDTAVDLGINY
                     VDSADIYGGGQSSTIFGQALKQAHVSRDQLYIQSKGGIVPGKRYDFSKQHILAAVDGEL
                     QRLGVDYLDTFLLHRPDALMEPEEVAAAFDKLQTSGKVRHFGVSNFNPMQVDMLQAALN
                     QRLIINQLQFGIMHTGAIDFGLHTNMQDERSLNHDGEMIEYSRLHKMTIQAWSPYQYGN
                     FAGIFLDNPKFPELNNAMQALADEKQVTKSAIATAWILRHPAHFQVILGTMNPEHLAQN
                     AAGADVTLSRQEWYDIYFAAGNDLP"
     CDS             8383..8907
                     /locus_tag="ctg5_7"
                     /transl_table=11
                     /translation="MTSTCTICERIKLIQAHQNPYFVYELTTGYVVLADSQYFEGYTLF
                     LAKHHVTELHHLPAHEKLRYLEEMSIVQEACAQAFHADKMNIELLGNGDAHVHWHLFPR
                     HNGDTPNPGPVWWTPLETIYGDDVSLDIPRLSRLKRTLSVAIEATLNAREAELQALEAL
                     TRPASHRIDSN"
     CDS             complement(9002..9247)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GlcNAc_2-epim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_8"
                     /sec_met_domain="GlcNAc_2-epim (E-value: 0.00021, bitscore:
                     13.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTAPLSSFEKNIPAVTELLAVDAELQTFFVALTPGYQREWARFI
                     FGTKAQATKERHIEVMKTVFRAGYKSKRAYDSRSDK"
     CDS             9420..9848
                     /locus_tag="ctg5_9"
                     /transl_table=11
                     /translation="MPKFDITLISPERAKAMLTEYKEQRKNSVPHLAHPGRYILPDYKL
                     TRRRAAFKIVKHTFLTPHYKSYVAMDSDNGHTLWFHNFGSLTEALFWLETGLKISDTDS
                     HSNYKEWMAKHTTEIETFKDLLREQKHKQGPKTKKKAK"
     CDS             complement(9951..10592)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_10"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 1.5e-19, bitscore:
                     63.8, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAISNGHVSFKRPAWLGDSITANNGLATVHYHDILAADWDVERSD
                     NLGISGSTIGSRYDAMAARYQAIPEDADFIAVFGGVNDYGRNQPLGQYGDCDMTTFYGA
                     LMVLLTGLQTNWPTVPKLFISAIHIGSDFGGSFSAVTNGLGYRQSDYEAAIAQMTADYG
                     VPHLSLYRDAGMTFAIPAQAAIYSVDTLHPNNAGHRVIARKLQSFLDSHF"
     CDS             complement(11608..13275)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BCCT"
                     /gene_functions="transport (smcogs)
                     SMCOG1001:betaine/carnitine/choline family transporter
                     (Score: 410.4; E-value: 2.8e-125)"
                     /gene_kind="transport"
                     /locus_tag="ctg5_11"
                     /sec_met_domain="BCCT (E-value: 4.6e-125, bitscore: 410.4,
                     seeds: 90, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSSRFIILKSKNIDWWVYLPTIGLFAAASVVLLMGGHSLETSLS
                     GILNWLTNNMSWLYMSVYVITFIFFIYLGFSKLGKTKLGDPDDKPEFSTYHWGSMVYAT
                     GIDASILMLSMVDPLRYLQSPSFGVKPFSTSAYNYAHMLGQFNWGPMAWMMFAPATIAI
                     AYAMYVKHIKVQRLSAAISVLQGPGKGKQIARNTIDFLVIIGIMGGVGTSVGMEIPVIS
                     KVLSAVTGIADTMTLKLGLFALLFVIFAMAVFNGLKKGIGRLSAAHVWLAIGFLIVVLI
                     VGPTLYILNSETNSIGLFVNKFITLSTNTAPNGHATAMQRQTIFYWGWWLSFMPVMGLF
                     IARISRGRTIRQVLGGMLLWGSLGCVSFYAILGGYALYLQRMGIVNLVHILNTQGQAAV
                     IAAVLSTLPLKMIMLALYCLSCFIFLATTVSSFAFITSSFTSKKLAAGEQPSRFNRMSW
                     VVIFLVFSLGLVTVGGFESIQSICAMSGFPLTIVALVLLYSIHHDLTTDPVKEAAKANA
                     KAAELARRKRLARDVEITTKTDYARERRTARKRETEAD"
ORIGIN
        1 gatcaaactc tcaaattaat gatgagttct aaaaagctca tttaatgttg tactaaaatt
       61 tatttgctag cgaattgact tcgcaaatgt tttgctcttg attcaaaatc aagagaccct
      121 acacatttga ttcgtcgaaa ctttgttcag ttttcaaaga tctaattccg tgtgttaatc
      181 gcttaacaca acttaatcat cataacatct taatcaatat cttgtcaaca acttttttta
      241 agaagtaact tgattaattt gtcgtggttg ccattgcgac aacagaaact atcttaccaa
      301 ttactgaaga agttgtcaac aactaatttc aataattatt tggtggtgag atgtatctgc
      361 cgtagcagca acgtttacta atataccaat tgaagtaaaa agtgtcaaca ctttttctga
      421 atttcttttt attaatagtc aaaccagctt tctttctcta tactatttaa ttaaaggagc
      481 gactaaatta tgctagcttg gctaccattc tttttgattt cattaatgtt tattgttcta
      541 ctatacgctt gtgcgcgatc agcgcgcaca aatatccagc gttttaagca actcagttta
      601 attgcctttc tctgggtctt aactgctttt tgctacacac ctaccagtta caattttggt
      661 acccaactcg ttattcaata tattcaatgg ggacccgtta agctgaacgt gattcctttc
      721 caacaacttg acattgaatt ttggctcaac gttctcctca ctgttccatt gggcggttta
      781 ctggcatgga attttcccga cttgccctgg cgtcgtttta tttggttggg atttcttacg
      841 gggctaacac tcgagctggg acaattcatc cttgactggt tggttaacct caaacgttgg
      901 gttgatatcg atgatgtcat cacaaattgg gctggtgtca ttatcggtgc cgctggttat
      961 aaaattgcac gtcatgttcc cggacttcgc tggttgcaaa aataacgtat atatagaagc
     1021 aaaaagcaaa atagcgtttg cttagcaccc acaagtgcca aacacttcag cggtctagct
     1081 gtcatgaaat cgtaattaaa taagcgtcgc agccttaagt ggctgcgacg cttatttaat
     1141 ttaactacta actattaatg aagctgccat catcaggatt caaaaaacag atcgaatact
     1201 cgcttacgat cttggttcca gacctgattg tcactagttg gataaactcg atttgttaac
     1261 acaaccagcc caatttgacg atccaaatca aaagcaactg ccgggccagt aaaaccagta
     1321 tggaaatatt gatgtcgtcc cgcacgtcgt tcccaaccta acgtccggcc attttcgtca
     1381 tactcgccta accagtcaaa gacattttca tccagcaccc gtttgccttg atattcacca
     1441 aagtttaaca tcatttcaat aaatacggat aaatccgtca gcgttgagaa caagcctgcg
     1501 tgaccactct caccattcaa caaaaaggct ttataatcat gcacctgtcc ttgaatctga
     1561 ccccgccgcg gatcaaactc cgtcggcaca aaccgaatct tcggacgatt taagttataa
     1621 cccgtattgg tcatcgctag tggatagcaa acgtggtctt gaatactccg agccaatgag
     1681 ccgtcaaccg cacgaataat ccatcccaat aaaataaatc ccaggtctga atagacatac
     1741 gttgtccctg gtgccgtgac gagtggcgca tcataaaccg ctttgatcag atcttcacgt
     1801 tgcatcttat ccaggttatc aatatctgcc ggtagcccac tattatgaag taacaagttt
     1861 ttaatcgtta tttcaggatg agtgaaccca ggtaaagacc gggcaaccga gtccgttaaa
     1921 tgaatcgtgt ggtccgataa caactgaaaa atcctcgtcg tggtccctac aaccttagtt
     1981 accgatgcta ggtcataaat catcgcagga tctaagccca cggcaaactc atcgcggccc
     2041 tgcttaccat gatagtattg attgatacct ttaggggtga tcaagctaaa cgacgcccca
     2101 taaatgtcgc cagcttcaat acaactgtca atatattgtt caatttgttc gagcatccgc
     2161 attacgccca cctttcacta cattcactag tttctgctta tcttctttat gataacgaac
     2221 ttcctcataa aatcaacggc aaacgctttt aacaccctcc acacctcgtt gcacttttta
     2281 ttaattaact agttaaacac ttgttacatt atggacaata ttccacttat atatcaaaac
     2341 aagtcttgtt tttagccgtt ttctaaatat aattaagtga attaccaatg cctatctagc
     2401 tatgtaagta ctgttatatc aacgttaata gtcaactttt caataataga ttgcaaaaaa
     2461 ataacccaaa cgtgaaataa atcacctgaa agcggttaca aatccagcaa aaaatgttat
     2521 gattcaaata tagaatttta tcaatcattt gattggattc aaattatgga ggcgagaaaa
     2581 tgattacatc agaaaagaca acaaaaccag cagcttggaa aggtttcaaa ggcgggcact
     2641 ggcaggaaga aatcaacatt cgtgatttta ttcaaaataa cttcacacag tacaatggcg
     2701 acgaaagctt cctggccgga ccaacagccg ctactaagac cttgaatgac aaagtcttag
     2761 aattaaagaa acaagaacgt gccgctggtg gtgtgttgga tgctgatact aaagtcgttg
     2821 caacgattac ttcacacggc cctggttata ttcaaaaaga tctcgaaaag attgttggtc
     2881 tccagactga caagcctttg aagcgggcct tcatgccatt tggtggtatt cgaatggctg
     2941 atgacgcttt gaaatcatac ggttataccc ctgatgaaga aaacgacaag attttcactg
     3001 aatatcgcaa gactcataac caaggcgtct tcgatgttta tactcctgac atgcggaaag
     3061 cacgtcacta caagatcatc accggactac cagatgcata cgcacgtggc cgtctcattc
     3121 ctgatcttcc acgggtcgct gtttatggga tcgatcgttt aatggaagac aaagctaatg
     3181 actttgccca cattggtgat ggtgaattga ctgatgatgt tattcgcctc cgtgaagaag
     3241 ttcaagatca ataccgtgct ttagcagata tgaagaagat ggctgccagt tatggctacg
     3301 atattagcaa gcctgcaact aatgctcaag aagctattca atggatgtac ttcgcttact
     3361 tagctgctat caagacccaa aacggcgctg caatgtccgt tggccggatt gatacaacga
     3421 tggacatctt catccaacgt gacttggaca atggtgttct ggacgaaagc caagctcaag
     3481 aattaattga tcaattcgtc atgaaactac ggatggttcg gttcatccgt actgaagaat
     3541 acaattctct cttctctggt gacccaatct gggcaacctt atcaatgtgt ggtttaggcg
     3601 tcgacggtca acaccatgtg actaagaccg ctttccggat tttaaagact ttggacaaca
     3661 tgggcgccgc accagaacca aacatcacga ttttatggtc agaccgctta ccagaagact
     3721 tcaaacgtta cgcaactgaa gtttcaatcg acagttcaac cattcagtat gaaaatgatg
     3781 acttgatgcg ggtacaatgg ggtaccgatt attatggcat tgcttgctgt gtttccgcac
     3841 aaccaattgc tgatggaatc cagtacttcg gtgcccgggc aaacttagcc aaagcgattc
     3901 tttatgccat caatggtggc cgcgacgaaa ttgctggaga tcaagttggc cctgcttacg
     3961 aaccaattac ttcagaatac atcgattacg acgaattcat gaagaaatta gacaagcaaa
     4021 tggattggtt agctgacact tacgttaact cactgaatgc aattcattat atgcatgata
     4081 agtactacta tgaagctgcc caattagctt tgaagaatac tgatcttgat cggacctttg
     4141 caactgggat ttctggctta tcacatgccg cggattcaat ctcagctatc aagtatggtc
     4201 acgttaaagt aattcgtgac gaacgtggta tcgccgttga cttcaaagcc gacaatgact
     4261 acccacgtta tgggaacaat gacgatcgcg ctgatgacat tgctaaatgg ttagtcaaag
     4321 aattatacag caagatgaac acgcatcacc tctatcggaa tgccaaactt tcaacttctg
     4381 ttttgacgat tacctccaac gttgtttatg gtaagaacac tggtaccaca ccaaatggcc
     4441 gtcaaaaagg cgaaccattc tcaccaggtg ctaaccctgc atacggtgct gaaaagagtg
     4501 gtgcattagc ttcacttctt tcaactgcca aattaccata ccgttacgca actgacggga
     4561 tttccaacac gttcggcgtt actcctaaca cgttaggcca tgacctcgaa tcacggaaag
     4621 acacgttagt aaacatgtta gacggttaca tgaagaacga tgggatgcac ttgaacatca
     4681 acgtcttcaa taaagacact ttgattgatg ctcagaaaca ccctgaagaa tacccaacat
     4741 taacggttcg ggtttctggc tactgtgtct acttcgcaga tttaaccaag gaacaacaag
     4801 atgacgttat ttcacggaca ttcttcgaat caatgtaaca tttaatcttt aatagttaag
     4861 aaggcgaaag gctcatggaa aacaaacaag tttcaacaac gcaagcggcg gcaaaggagc
     4921 ctttgatagg ctacgttcac tccatcgaaa cgtttggctc cgttgacgga ccaggtatcc
     4981 gttacgtggc attccttcaa ggatgccaca tgcgttgcca atactgtcac aaccctgata
     5041 cttggaaact caacgttggc gatcaaatga cggccgacga gattctcgaa gacgcggcta
     5101 aataccgggc tttctggggc aagacgggtg gcatcacagt cagtggtggt gaatcactgg
     5161 tacaaatcga cttcatctta gacttattcg aaaaagccaa ggcgatgaat atcagtactt
     5221 gtctggatac ctctggacag ccttttaccc gagaacaacc tttctttgac aagttcgaac
     5281 gtctaatgaa ggtcacggac atttcgttgg tcgacattaa gcacatcgat tctgccaaac
     5341 acaagcagtt gacccagtat gggaacgaaa atatcttgga tatgattcag tacatggccc
     5401 aacaccacga tgatatgtgg attcgtcacg tcctggttcc ccaacggact gattacgatg
     5461 aagacttgaa gaaactcggc gattacattg ctaagattcc aaacgacgtc gttcaaaaag
     5521 tcgaagtatt gccgtaccat actttgggcg ttaaaaaata tcatgaaatg aagatcaagt
     5581 accggcttga aggaatcgag tctccaaccc aagatcgggt ggcaaatgcc gaaaaactac
     5641 tgcacaccgc tgattacaac gggtacaaga catggatgcc attgccaaaa ctttaaatcg
     5701 gcatttctag catgactaaa acaccagcga tacaatcgtc tacggatggt tgtgtcactg
     5761 gtgttttttt gctggctcga cgcatgcacg tattgctggc tggaattagt acagtggcac
     5821 gcaaaaaagg cgccgcaagc ctaaaccagc aacgtctttc cttaatcatg ccctatccaa
     5881 tgaccgtcag cccttgaact agctgcgaac aggccggcca ctaactatga atgcctagtt
     5941 ccattcgagc ttcgcgggac atcatacttt cgttccaagc aggttcccac acaatctcaa
     6001 tctcgatatt gttaacttct ggtaatttga tcagttcatc gtgaatgtcc ttagccaacc
     6061 attcggtcaa aggacagccc gcaatggtca acgtcatggt aatttcagcg gtcccctccg
     6121 ccgtcaattg tgcatcatag atcaacccca agttaactag atcaattcct aattcagggt
     6181 caatgacatg tcctagcgcc tcgaaggccc ggtctttaaa cgttgttgtc atcgtatctc
     6241 gtccttccat accagcttga attcactgat taatcacgcc aacgtttcgc ggtataagtg
     6301 ccaccacact tgatacacgt catcgttata taaagcgctt tcttgtctac ttctattgta
     6361 ccgtatgtca gcccatattc aatcaattat tagcgctaat tagccgactt ttcaaacgat
     6421 cggtcaatca gcaaattatg cgactatttc tcgaaaaaat ttactataat ccccgatata
     6481 gcagcgtttt gagtcactat tgatttttat tgcgaattcg cggttgtttt tgttgtaagc
     6541 gtttgcggtt tatgctatta tactaagtga ggaaaggaat taatcctcga ttagcaaagc
     6601 ttctcaaaag agtttggctg tcgctgtaat gttagacagc tagtatcaca gtttgggtcg
     6661 ttatcgaaac cgttttaagc gccgtgaagc gttatcggtc tagcgagtgt cgtgagattt
     6721 acgttggatg actgaacgtt gacccttaga taaacgataa ccgcaaagaa ttaattggca
     6781 ttagaatgac gaacagattt taactaagtt ttagttggaa acaggtgtct ccgatgacca
     6841 gttgttagtt ccacattacc agttccattt gtagactcag gtattacaaa gtttaaacgg
     6901 aggtgcatgt ctgttacgaa gacattccca agttttaaac gcgagtttga ctttcgttaa
     6961 aacccgtcta acgagtcaca atcaagtaac aaccttactt tagatcgact atagcagata
     7021 gttacaataa atacgggtta gtccgttaga agttggacac gcgtaaaatt gaatagcatg
     7081 aaggtgtatc atattaacac tgaacaattt ttcattgcta atcaggatta ttcctcataa
     7141 gtagaactca agtagagaag ccttgggttc tatttttttt gctctaaaat cagatttacc
     7201 aacagtcggc accagtcgta accgtttaca tcctcttacg aaaaccgtat actgaattta
     7261 aatcaagttg cacattgagg aggactttag ttttgaaaac gattaattta ggtcacagca
     7321 atattcaagc ttccagcgtg gcgcttggca tcatgcgcat ggacgccttg gatgtcgctc
     7381 aagccaccaa ggttatcgat accgctgttg atttaggcat caattacgtt gattcagctg
     7441 atatctacgg tggtggtcaa tcatcgacca tcttcggtca agcactcaag caggctcacg
     7501 tatcgcgtga tcagctctat attcagtcaa aaggcggcat cgttcctggc aagcgttacg
     7561 acttttccaa acagcacata ctggcagccg tggatggcga acttcaacgc ttaggtgttg
     7621 attatctcga caccttcctc ctccatcgac cggacgccct gatggaaccc gaagaagttg
     7681 ctgccgcttt tgacaagttg caaactagcg gcaaggtgcg ccactttggc gtctctaact
     7741 tcaatcccat gcaagttgac atgcttcaag cggcactaaa ccaacggctc atcatcaacc
     7801 aactccaatt tggtatcatg cataccggtg cgatcgactt tggcttgcac acgaacatgc
     7861 aggacgaacg tagtcttaac cacgacggcg agatgatcga atactcacgg ctccataaga
     7921 tgacgattca agcttggtcg ccttatcaat acggtaactt cgcgggtatc ttcttagaca
     7981 atccgaagtt tccagaactt aataatgcca tgcaagcact cgccgatgag aaacaggtca
     8041 ctaaatcagc tattgcgacc gcatggattc tccggcaccc agcccacttc caagtcatcc
     8101 ttggtacgat gaatccggaa catctagctc aaaatgctgc tggagcagac gttacgcttt
     8161 ctcggcaaga atggtacgac atttactttg cagctggcaa cgatttacct taatcacgat
     8221 cgacctaaca gaattgacga ttagttttta caatcaaaac gacgacccca aatcaggatt
     8281 gattttcagg tcgtcgtttt ttagacgttt cactaacatt tttgatgtac tcaccacatc
     8341 tacgcgtata cttaatctta tcaagactca ggaggcgagc gaatgacatc cacttgcacg
     8401 atctgtgaac gaatcaaact aattcaggca catcagaatc cttatttcgt ttacgaactc
     8461 acaacgggct acgtggtcct tgctgatagc cagtactttg aaggctacac gctcttttta
     8521 gccaaacatc acgttaccga attacatcat ttaccggcac acgagaagtt acgatacctt
     8581 gaggagatga gtatcgtcca ggaagcctgt gcgcaggcct ttcatgcaga caaaatgaac
     8641 attgaactac tcgggaatgg tgacgcgcat gttcattggc acttatttcc tcgccataac
     8701 ggtgatacgc ccaaccccgg tcccgtctgg tggacaccgc tggaaacaat ttatggtgat
     8761 gatgtcagtc tagacattcc ccgtttaagc cggttaaagc gcacgctcag cgtagcaatt
     8821 gaggccacgc ttaatgctcg ggaagcagaa ttgcaggctt tagaggcact cacaaggcct
     8881 gctagccaca gaattgacag caattagacc aaatcaggac ccagacccgc ttagatcttg
     8941 gtggctacac cccaattctt aatcgcaatc cgtcaccgta tttcaaattg ccaaaatcca
     9001 cctatttatc cgaccgacta tcatacgctc gcttagattt atagccagct cgaaaaaccg
     9061 tcttcataac ttcaatgtgc cgttccttag ttgcttgtgc cttagttcca aaaataaagc
     9121 gggcccattc gcgctgataa ccaggtgtca aagccacaaa gaacgtttgc aattcagcat
     9181 caaccgctaa caattcggtt accgccggaa tatttttttc aaatgaactg aggggtgctg
     9241 tactcataat caaacctccg attagtttta cttaaattta ctgtaagaaa gggaaaatcc
     9301 ctaattttca ggtttttata tttcgaattt tcataaaatt gcgctatcat tatagtataa
     9361 gtattattat ttgactacta taattgacca tactgctatt caccaagggg agccctgcta
     9421 tgccaaaatt tgatatcacc ctcatcagtc ccgaacgcgc taaagcgatg ttgactgaat
     9481 ataaagaaca acgtaagaac tctgtcccac atctggccca tcctggccgc tatatcttgc
     9541 cggattacaa attaactcgt cgccgggccg cattcaaaat tgttaaacat acctttttaa
     9601 cgccccacta caagtcttac gttgccatgg actctgacaa cggccacaca ctctggtttc
     9661 ataatttcgg ttccctaacc gaagctttat tctggttaga aaccggcctt aaaatcagcg
     9721 ataccgactc ccattctaac tacaaggaat ggatggctaa gcacactacg gaaatcgaaa
     9781 ccttcaaaga cttgctgcgc gagcagaagc ataaacaagg gcccaagact aagaaaaaag
     9841 ccaagtagcc cgttttgaca cctagattca gataagcagc agtacgccca ttagcgtgct
     9901 gctgctttta tttacgatca actgtgccat tcattactga ctaggccaac ctaaaagtgg
     9961 ctatccaaaa acgactgcag cttgcgtgca atcacgcgat gaccggcatt gttcggatgc
    10021 aaagtatcca ccgaataaat ggccgcttga gcgggaatcg caaacgtcat tcccgcatca
    10081 cggtacaagc tcaaatgtgg gacgccatag tccgcagtca tctgggcaat cgctgcttca
    10141 taatctgact gacgataccc gagaccatta gtcaccgcac taaaactgcc gccaaaatca
    10201 gagccaatat gaattgctga aataaataac ttcggcacgg tcggccaatt cgtctgtaat
    10261 cccgtcagta acaccattaa cgcgccataa aatgtcgtca tatcgcaatc accgtattgc
    10321 cctaacggct gattccgacc atagtcattg acgcccccaa agacagcaat aaaatcagca
    10381 tcttcaggaa tagcttgata gcgcgccgcc atcgcatcgt agcgactccc aatcgttgaa
    10441 ccagagattc ccaaattatc gctccgctcg acatcccaat cagccgccaa aatatcatga
    10501 taatgcaccg tcgccaaccc attattcgcc gtaatcgaat ctcccaacca cgccggccgc
    10561 ttaaaactaa catgcccatt actaatcgcc atagccaatc ctccctttac tatcatcgct
    10621 atcattctaa tccatcccac ctgaattatg gtataaagat gcctttattt aaagtcaaca
    10681 gccaccagct taggcccgct ggaaacagtt ccggttagcg taaacctgct tagttcgttc
    10741 gtcctacgcc gccctccagg catttctgcc aattgctgga acgcggtgga cacagattta
    10801 agccgaagac cacgtcttaa atactggtct tccactaacc aagccaagga cgcttgctaa
    10861 gtggaatttc accgctgagc attggccgaa acgccttcca gtcgggacag tattcgaatg
    10921 gcggacgaag atgtacccaa cttttgatga atttgtcatt gttctccata aacagtaatt
    10981 ttgttaatca actgttaggt cgaaaagata ttgggatagc tcgctatttc ggaattacta
    11041 tagtaataat agaacacctc aacaaagtgg ttagggtaac cctaacgtct cgtttaaagt
    11101 tcctgtatca aaataaccaa cgaccaattg tgccgagtta agtggccgtt catcagccat
    11161 tcgagcggct tcctgaaacg tgttcggtgc cactaaagtc tgtgcttgct atgccaacgg
    11221 acaaatgccc aaaccgcatt aatccgttgg ctagacaatg ctcggcttca acccgtggct
    11281 tgagactgga ggggctgggt gacaatgctc agtagccaaa ttattcttag tcggaagtga
    11341 tttccttccg gcttagaata agactcgtat ttgagatgac gcgggttatt cgttagctca
    11401 aatcgatgtc ggctgcgttc cagcaattgt cacccagccc cggaggtcgg aataggacgc
    11461 tcactggctg acgaacagaa aaccaaccct aaaaggcatc tttctaccat tatttcaaac
    11521 aggtgggcca agcttaaaag gctcgtatta tggaaatcca taatacgagc ctagtttaat
    11581 tgatatattt agttcaactg agtagcgcta atcggcttcc gtttcacgtt tccgtgcagt
    11641 acgccgttcg cgtgcgtagt cagttttagt tgtgatttca acgtcacgtg ctaaccgttt
    11701 ccggcgtgct aattcagctg ctttggcatt ggctttcgca gcttccttga ctggatcagt
    11761 cgttaagtcg tgatggatcg agtacagtaa gacgagcgcg acaatcgtta atgggaagcc
    11821 agacatcgca cagatggact gaatcgattc aaagccaccg accgtgacaa gccccaatga
    11881 gaagactagg aagataacga cccagctcat ccgattgaaa cgacttggtt gttcccccgc
    11941 ggccaacttt ttactagtaa atgacgaggt aatgaaggca aatgaagata ccgtcgttgc
    12001 taagaaaata aagcaagata ggcagtacaa agccagcata atcatcttca atggtaaggt
    12061 cgacaatact gctgcaatca cagcggcttg tccttgcgta tttaagatat gaactaagtt
    12121 aacgatgccc atccgttgca agtataaggc ataaccaccc aagatggcgt agaaactgac
    12181 acaacctaat gagccccata gcaacatacc accgagtacc tgacgaatcg tccggccccg
    12241 agaaatccgg gcaatgaata agcccatgac tggcataaag gataaccacc agccccagta
    12301 gaagatcgtc tgccgttgca tggccgttgc gtgaccattt ggtgcagtat tcgtgctcaa
    12361 cgtaataaac ttattgacaa acaagccaat actattagtt tccgagttta aaatatacaa
    12421 agttgggcca acaattaaaa caacgattag gaagccaatc gctaaccaaa catgggcagc
    12481 acttagccga ccgattccct tcttcaagcc attaaaaaca gccatggcga aaattacgaa
    12541 taataaggca aataacccta actttaaagt catcgtatcg gcaatcccgg taacggcact
    12601 caaaactttt gaaatgacgg ggatttccat cccgactgaa gtaccaacac cacccataat
    12661 cccaataata acgagaaaat caatcgtgtt ccgggcaatt tgcttaccct taccaggacc
    12721 ttgtagtact gaaattgcgg cactgagccg ctgaaccttg atgtgtttaa catacattgc
    12781 ataggcaatt gcaatcgtgg ctggcgcaaa catcatccac gccattggtc cccaattaaa
    12841 ttgtcccagc atgtgcgcat aattatatgc agaagttgaa aacggcttga cgccgaatga
    12901 agggctttgg aggtaccgta acgggtcaac catgctcaac attaaaatgc tggcatcgat
    12961 cccggtcgcg taaaccatac tgccccagtg atacgttgaa aattctggtt tgtcatcagg
    13021 atcaccaagt ttggttttcc ctaacttact aaaccctaag taaatgaaaa agataaaagt
    13081 gatcacatat accgacatat aaagccagct catgttattt gtgagccagt tcaagatgcc
    13141 acttaaactc gtctccagcg aatggccccc cattaataaa acaacggaag ccgccgcaaa
    13201 gagcccaatt gttggtaaat agacccacca atcaatattc ttacttttta aaataataaa
    13261 cctgctactg agcatatact ctctatattt agatcaaatt cgtggttctt cctaccagca
    13321 atggtagtcc ccacgcgtaa atttccgact agcaatcggt acacccctcc gagttaatcc
    13381 tcggagcact cagcaccctg actgtatcag gtttgaccgg cattgtcatc cgcattctgt
    13441 ttgtgctaac tcaaaatcag tagcagaatt tccttctttc cgttggttga atccggacaa
    13501 cgccatactg acaaatgatt tttaattgct taatcgacgt tggtgttcat cttgtttagc
    13561 tagtgtttct attaccatcg tgcctttagc acacgaccgt cgtcacacca cgtaacgatt
    13621 aatggttaca ctgctcttgc taatagataa cccccttgaa tcaccagata agcccaccgc
    13681 acaactgtta gattaattgc ttggtgcacc aaaaaagcgc ttagtaccgg gtaacaagtt
    13741 accacctgca cagcgcacgt tggcttatac aaatgctgat ttcagtattt tctgatatct
    13801 gatgttcgtt tataagtata ctagtattaa atcagaagta aaatcaacca ttttgagccg
    13861 tcgaggccta acccgtcaag gattagacga gttttacacc catatttttt ctgaaacttt
    13921 ttaaaagttt tcgtaataat tagtttttag tttagaatca ttcttatctg tttcaattaa
    13981 accgatttca tgttattctt gtaacaagta aaaaaacgtt atcatctaaa aggaggggaa
    14041 ctgcatgcgg cactactata aattaatttt aacggtcagc gtcggtatca ttgcggttat
    14101 tttacagttt ggtttgcact accaattggc agcacaaatc atcattacat taatggggtc
    14161 acttatggcc ttatcaatgt tagttgagat gatcaaaacc ttacgttcag gtaagtacgg
    14221 ggttgattta ttagcaatta cggcgattgt ggcaacacta gctgtcggcg aatattgggc
    14281 tagccttgtc gttctaatta tgctcactgg gggtgactcg ttagaagatt atgcggccaa
    14341 acgagcgaat accgaattga aagccttgct cgataattca ccacgtattg cccaccgctc
    14401 agtcgccggc caattaacag atattgccgt tgaagatgtc caaattggtg atcagctagt
    14461 cgtcaaacct ggtgagctag ttccagtaga cggtcacctt attcaaggaa cggcactctt
    14521 tgatgaatct tcattgacgg gtgaatctaa accagtcgac aagcacgttg gcgatgacat
    14581 tatgtctggt gcggtcaacg gcgatagtgc cgttacaatg gttgttgata aattagccat
    14641 tgatagtcaa taccaacagt tagtcaaatt ggttaaagaa tccgaatcac gaccagccaa
    14701 attcgtacgg ctggccgatc gctatgcagt cccattcacc ttggtagcat acgtcattgc
    14761 cggagtagct tgggcattca gcggtgatcc ccaccgattt gcagaagtcc tcgtagtggc
    14821 ttcaccttgc ccgctgattc tcgccgcacc cgttgcactc gtctcaggga tgagccgaac
    14881 tagtcggaac ggaatcgtgg tcaagactgg ggacatgttg gagaagttat ctacggctaa
    14941 gtccgccgcg tttgataaga cggggaccat taccagtggt caattaacag tcaaccaaat
    15001 tgttcctcag cctggtttta ctgccgaaca aatcttgcac ctcgcagcga gcgctgaaca
    15061 aaactcaagt catatcctgg cccgctcact cgtcaagtat gcgagtgcca ctagcctcag
    15121 cccggcaaca caattagcag aagtaacggg taatggggtc acggcaacga ttgagcagca
    15181 acaggtcaaa gtgggcaaac ttaaattcgt cgcaccgact acaaccgcca agccacttgc
    15241 tactactgct atctacgtcg gcatcgatga ccagtacgcg ggttacatca cgtttatcga
    15301 caatgtccgc cccgaagcag ccgccacgct tcaagcactc cacgctgagg gcgttcaaaa
    15361 cgtcatgatg cttactggtg accaacaggc aattgctgat catattgccg ccgatgtcgg
    15421 tatcgatacc gttgctgccg acctcctacc cgcagataag attgcccact taaaggctgt
    15481 accagcggcc gaacgccccg ttatcatggt tggtgatggt gttaatgacg cgccttcctt
    15541 ggctgttgct gacgtcggca ttgccatggg cgcccatggc tcaactgctg ctagtgaatc
    15601 ggccgacgtc gtcatcttaa aagacgatct cagtcgcgtg gtcacggcgg tgcgcattgc
    15661 taaagatacc atgcaagtgg ctaaacaagc cgtttg
//
