LOCUS       c00004_gnlPro..        15651 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DADKGAAK_4.
ACCESSION   c00004_gnlPro..
VERSION     c00004_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-03 20:53:33
            Original ID  :: gnl|Prokka|DADKGAAK_4
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 332142
            Orig. end    :: 347793
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15651
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[342142:345582]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13440
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15651
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15651
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="2"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(48..1601)
                     /locus_tag="ctg4_262"
                     /transl_table=11
                     /translation="MKCKFSLLLFLCVLSLWGQAQSLNLQELVNKKQFQEVVARADSLT
                     PADSADYATMSAIGQAYEGLLRYKEAYQCFSHCLKMDTNNVDALNAVARNAINFGRIAE
                     AKQCYRKVLGTDSMNFYANYQLARLYYQLGDYGRATEHYHILASIEGENPSILTGLADC
                     HIKRGTGPNTMIALSLYARALELNPENVRVASSLINTLLRMGDGQGALQVCDTALFYNP
                     DNSQIRQSKGMALYMTKDYKQADSVYTGLLADGDSSFLNLKYAGAARYMSGHALDGVEL
                     LEKAYEIDSTDVETVMLYGASLGKTYDRKRAYELFDLAETNMQPKKFLVNMLMTFRGDA
                     LERDGRWPEAEKLYYAAWKEDPTQLHFLYKISTQYWDVDPGLFQQEEKLQKTIFSRYTY
                     LTAYMKTDKSQKYLYNYRPFLEAVCEDAFFRNADEVTMLAPDGKKTKLAVADLHALVAQ
                     LPQMPEDERLRREKMQEHIKKAREKEKELRKSGAKLDTLALSKEEKEKALKMLKDADLE
                     "
     CDS             complement(1635..3371)
                     /locus_tag="ctg4_263"
                     /transl_table=11
                     /translation="MTPEFAYFLKVNVAFILLYAFYRLFFYKDTFFKLRRTILLAFFGV
                     SLLYPLMNIQDWIREQGPIVEVIQMYSAILPETTITPGNVPQTNWHDLLLSGISYLYWS
                     GVIALSFRFLVQLSSILLLARRSEVTLIRNVRVHLLNKPAGPFSFFRLVFLHPDSHSEK
                     EIDEILVHECTHVSQWHSIDVIICELVCIICWVNPFVWLLKREVRHNLEYLADDTVLES
                     GYDSRSYQYHLLGLAHTNRSVTSLSNNFNMLHLKNRISMMNKKRSRSIGRTKYLIFIPI
                     VGALLILSNVDALARITDELTESTFADVLLPEAILPFPFVGDASPAEKREEYVLSEEGI
                     EATRRARNQVFTVVEVMPEFPGGQGALLKFLATNVRYPESAVKNGIEGRVSCSFVVGKD
                     GAISEAEVIRGVSPELNEEALRVINSMPVWSPGKQRGKAVNVKYTVPVTFRLSGGKKKT
                     SSRIVQRQIKEVDTSGRVFTVVQQMPEFPGGQASLLKYLATRIKYPAIAQENGIQGRVS
                     CSFVVDTDGSLKNIEVIRGIDPSLDREAVRVIREMPKWNPGVQNNMAVAVKYTVPVTFR
                     LQ"
     CDS             complement(3392..3754)
                     /locus_tag="ctg4_264"
                     /transl_table=11
                     /translation="MERLTRQEEDVMRWIWQIEPCFIKDILAKYEEPKPPYTTLASIVK
                     NLERKKYVKAKRYGNTYEYRPLIPQEEYKRTFMGSVVNNYFENSYKEMVSFFAKEQKIS
                     TDELKEIIDMIEKGRE"
     CDS             4360..5256
                     /locus_tag="ctg4_265"
                     /transl_table=11
                     /translation="MKMLSFILVLLLGGGMPAGNLLASDKEQNPHYITVKNSRDLQAYF
                     RYAPDRPIVISGHRGGMLDGYPENCIESFEKTLSYMESFFEIDPRLTKDGIIVLMHDET
                     IDRTTTGKGKVSDYTYAELQQFNLVDRNGNVTTFKIPTLKECLEWSKGKTILNLDIKDV
                     PLEVMADFIETEKPVNVIYTVHNAGQARYYLDRKPDAMFSCWCKNREEFDNYEKAGIPW
                     KQVMAYVGPKMEPEQQPLYDALHRNGVMCMISVAPTHDRAKTETEKTAGYQSEISTRPD
                     VIETDYPYLFQGLDLTK"
     CDS             complement(5507..6604)
                     /locus_tag="ctg4_266"
                     /transl_table=11
                     /translation="MTDKRIYQIGLTMINGVGDILARHLLQALGEAEAVFTEKQQLLGR
                     IPGIGSNIAAEIKRPEILQRAEKELAFIEKNNISCYYLTDTDYPVRMRECPDAPILFYF
                     KGNTDLDVTRIISIVGTRNATEYGRELTESLIKDLAKVIPDLLVVSGLAYGIDICAHRN
                     ALYNRLPTVAVLAHGLDRIYPSCHRNTAVEMLESGGLLTDFPSGTEPDRPNFLRRNRIV
                     AGISDCTIVVESAEKGGSLVTADIAFSYGRDVYSFPGRVGDSHSKGCNNLIRQNKAGLI
                     TSADDLLSALCWDIQAAATPVQMELFSASEQNPVLAIMRTRNEIHINELASVLEMPVHQ
                     LSMLLFELEINGKVKALPGNLYKLS"
     CDS             complement(6601..7008)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_267"
                     /sec_met_domain="HBT (E-value: 2.7e-08, bitscore: 28.2,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 5.8e-09, bitscore: 30.6,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYIFKLTDKVRDYECDLQGVVNNSNYQHYMEHTRHEFLESLGE
                     NFGKMHEKGVDGFVSRVEIQYKTSLRSGDSYISCLNVYKKGVKLVFEQDIYRASDNALA
                     TKGIVESVIVENGKLTRGEYFDEMLKRIEHT"
     CDS             complement(7008..8243)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_268"
                     /sec_met_domain="Peptidase_U32 (E-value: 2.3e-67, bitscore:
                     220.6, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPVGSYESLMAAIQGGADSIYFGIEGLNMRSRSSNNFTTDDLRK
                     IVALCREHGIKSYLTVNTVIYGEDLPLMREIIDAAKEAEVSAIIAADVAAMNYANSIGQ
                     EVHLSTQLNISNAEALKFYARFADVVVLARELNLKQVHEIYRQIVDQQITGPKGELVRI
                     EMFAHGALCMAISGKCYLSLHEMNASANRGACMQICRRAYSVKDKDSNIELDIENQYIM
                     SPKDLKTIHFMNKMMDAGVRVFKIEGRARGPEYVRLVTECYKEAVCAYCNDTFDEKKVA
                     AWDERLRSVFNRGFWDGYYLGQRLGEWSSKYGSGATKKKVYVAKGIKYFDKIGVAEFEM
                     ESGNLKVGDEILITGPTTGAVMQTIEEIRVDLKPVDETVKGERFSLKVNEKIRPSDRLY
                     KMEKVQLEKVFE"
     CDS             8648..9679
                     /locus_tag="ctg4_269"
                     /transl_table=11
                     /translation="MKIGTIDLGERPVFLAPMEDVTDISFRLMCKRFGADMVYTEFVSA
                     DALIRSVNKTQQKLNVADEERPVAIQIYGRDVPTMVEAAQICEAAHPDILDINFGCPVK
                     RVAGKGAGAGMLRNIPLMLDITREVVKAVNIPVTVKTRLGWDADNRIIVDLAEQLQDCG
                     IAALSIHGRTRAQMYTGEADWTLIGEAKNNPRIQIPIIGNGDVTSAEICKQRFEQYGVD
                     AVMIGRGSIGRPWIFREARHYLDTGETLPAESFSWYLDILKKQVEQSVERLDERRGILH
                     IRRHLAATPLFKGIADFKQTRVAMLRAETVEALFDILDSIPDKFHTGYGFQSDSQVSES
                     IDC"
     CDS             complement(9652..9810)
                     /locus_tag="ctg4_270"
                     /transl_table=11
                     /translation="MKKTHCKYKVYLLNTQEFVITFYCKFATFCFKIDTVCGFTLLLYQ
                     QSIDSDT"
     CDS             complement(10001..10756)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_271"
                     /sec_met_domain="Fer2_3 (E-value: 2.1e-25, bitscore: 83.0,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 6.1e-11, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.5e-05, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKGPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANAIPISKADADLAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFISAKLQD"
     CDS             complement(10784..12727)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.4; E-value:
                     1.1e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_272"
                     /sec_met_domain="FAD_binding_2 (E-value: 5.1e-59, bitscore:
                     194.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3.3e-37,
                     bitscore: 121.5, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERFAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDFQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFVEAEKAINARIAKLMNVKGKETVDSIHRKLGHI
                     MWEHVGMARDAEGLKEAIQMLKDLKKEFWSNVFIPGEANSLNVELDKALRLADFIEIGA
                     LMAHDALDRAESCGGHFRTEHQTEEGEAMRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     QFVVPQTRNYKK"
     CDS             complement(12766..13440)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_273"
                     /sec_met_domain="SucD_FumR (E-value: 2.1e-66, bitscore:
                     217.4, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLILFLVFHLCMNIAAVFSGEAYNVI
                     CGLLGSNWYALLGTLVLAAGVVVHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGVIVILFMVLHFTQFWYNMMFAELAGIHGDIHPQDGAAFINFYFQGNVVNTVLYL
                     IWFVALWFHLTHGFWSAIHTIGWNNTVWLSRWECISKWVATIICGLFAVITVIFYLNGV
                     GA"
     CDS             13700..14653
                     /locus_tag="ctg4_274"
                     /transl_table=11
                     /translation="MKTAIFSIGVFLISLFLGSCQPSETSCSVVDTGKALDYKIGNKLL
                     FSYNYTTVYPAPGVDSVYKRSGFIHPLKTLGGEVMTNCSPADHYHHFGLWYAWTKTTFE
                     GNEIDFWNLHKKQGTVRFRNFEHVSDNGFVATLDHVVYPDSPAEKVAMNERLEINIGTT
                     SLPGYYIDYHTTIRLASPSPITMEAYRYGGICIRTREDWNDQTAEMLTSEGLSRDEADG
                     SRARWCYYQGKAGNEKACILIVASPSNLNYPEPLRVWDKTVNKPAGDVMWNFSPTKQKA
                     FTLEPGKELSLSYRIYVLDKNINATTAEVLSDFERD"
ORIGIN
        1 ttctatattc cattatttat atcgattata ttgttcagct attctatcta ttccaagtcg
       61 gcgtctttca acattttcag tgctttctct ttttcttcct tactcagggc gagcgtatcg
      121 agtttagcac cgcttttacg caattccttt tctttttccc tggctttttt aatatgttcc
      181 tgcatcttct cgcgcctcaa acgttcatct tccggcattt gcggtaactg ggcgaccaag
      241 gcatgcagat cagcgacagc caactttgtc tttttcccat cgggagccaa catcgtcact
      301 tcatcggcat tccggaaaaa ggcatcttca caaaccgctt ccaagaaagg gcggtaatta
      361 taaagatact tttgcgactt gtctgtcttc atataggctg tcaggtaagt gtatctactg
      421 aaaatcgtct tttgcaattt ttcctcctgc tgaaagagtc ccggatcgac atcccagtat
      481 tgtgtactga tcttatacag gaagtgcaac tgggttgggt cttccttcca tgcggcataa
      541 tacagctttt ccgcttcggg ccaacggccg tccctttcca aggcatcacc tcggaaggtc
      601 atcaacatat taactaggaa ctttttcggc tgcatattcg tttccgccag atcgaaaagc
      661 tcataagccc gtttacggtc gtatgttttt cccagggaag cgccatacaa catgactgtt
      721 tccacatccg tcgaatctat ttcataggcc ttctccagca gctcgacccc atcaagtgca
      781 tgaccggaca tatagcgggc cgcccccgca tatttaagat tcaaaaaaga agaatcgcca
      841 tcggccaata gaccggtata gactgaatca gcctgcttat aatctttcgt catatagaga
      901 gccatccctt tactctgccg tatctggctg ttatccggat tatagaacaa ggcggtatcg
      961 cacacctgca aagctccctg tccgtccccc atccgcaata acgtatttat cagagaagat
     1021 gccacacgca cattttccgg gttcagctcc aaagcacggg catacaaaga aagagcgatc
     1081 atcgtattag gaccggtccc tcttttaata tggcaatcag ccagcccggt caggatagaa
     1141 ggattttcac cttcgatgga agcaagtata tgatagtgtt ccgtcgctcg accataatct
     1201 cccaactgat aatagagacg cgccaactga tagttggcat agaaattcat gctgtcggtt
     1261 cccaatactt tacgataaca ttgtttagct tccgctatcc ttccgaaatt gatcgcattc
     1321 ctggcaacgg cattcaatgc atccacattg ttcgtatcca tcttcaagca atgagaaaag
     1381 cactgatagg cctccttata gcgcaacagt ccctcatacg cctgcccgat tgccgacatt
     1441 gtagcataat cggctgaatc ggcaggagta agactatccg cacgtgctac aacttcctga
     1501 aattgttttt tattgaccaa ttcctgaaga ttaagactct gcgcctgtcc ccaaagggac
     1561 agtacgcaaa gaaacagtaa tagagaaaac ttacatttca taatggtatc gtattaatga
     1621 ccgattctgg tcaattactg caaacgaaaa gtaaccggaa ccgtatattt tacggctaca
     1681 gccatattgt tttgtacgcc aggattccat ttcggcattt cccggatcac ccggacagcc
     1741 tccctgtcca gcgaaggatc gattccacgg atcacttcaa tatttttcaa acttccatcc
     1801 gtgtcgacaa cgaaagagca agagacacgt ccttgtattc cattctcctg agcaatagcc
     1861 ggatatttta tgcgtgttgc cagatatttc aacaacgaag cctgtccacc cggaaattcc
     1921 ggcatctgtt gcactaccgt aaagacacga ccggacgtat cgacttcttt aatctgcctc
     1981 tgcacgatac gagaggatgt ttttttcttt ccaccggaaa gccggaaagt taccggtacc
     2041 gtatatttga cattaaccgc tttgccccgc tgttttcccg gcgaccatac cggcatggag
     2101 tttatcacac gcaaagcctc ctcattcagt tccggactta ccccacgaat cacttctgcc
     2161 tccgagatag ctccgtcttt tccaacaacg aaagaacagc taacccgtcc ctctatacca
     2221 tttttaacgg ccgattccgg gtatctgaca ttcgtcgcca ggaatttcag cagagcaccc
     2281 tgtccgccag ggaattccgg cattacctcc acaacggtaa acacctggtt acgggcacgt
     2341 ctggtagcct caattccttc ctccgatagc acatactcct cacgtttttc agcaggagaa
     2401 gcatcaccga caaaagggaa cggcaagata gcctccggta gtaagacatc ggcaaacgtg
     2461 ctttccgtca gttcgtccgt gatccgggcc aatgcatcga cattgctcaa aatcagcaag
     2521 gcgcccacaa tcggtataaa aatcaggtat ttcgtcctcc ctatgctccg ggaacgtttc
     2581 ttattcatca tgctgatccg atttttcaga tgcagcatat taaagttatt agataaagag
     2641 gtcaccgatc tattggtatg tgccaacccc aaaaggtgat attggtagct acgactgtca
     2701 tagcccgatt caagtaccgt atcatccgcc aaatattcca gattatgacg tacctctctt
     2761 ttcaacagcc agacaaacgg attcacccaa cagatgatac aaaccaattc gcaaataatc
     2821 acgtcaatcg aatgccactg gctgacatgc gtacactcgt gtaccaaaat ctcatcgatc
     2881 tctttctcgg aatggctgtc gggatgcaga aataccagcc ggaaaaaaga aaaaggaccg
     2941 gccggtttat tcaacagatg tacacgtacg ttacggatca aagtcacttc cgaccgccgt
     3001 gccagtaaca agatgctgct caactgtact aaaaaacgga acgataaggc aattacaccg
     3061 ctccaataaa gataagaaat accggaaagt aacaaatcat gccaatttgt ttggggaaca
     3121 ttgccggggg ttattgtcgt ttcaggcaaa atggctgaat acatttgtat gacttccact
     3181 atcggcccct gctcccggat ccaatcctga atattcatca gcggataaag caatgacacc
     3241 ccgaaaaatg ccaacaaaat ggtacggcgt agtttaaaga aggtgtcctt ataaaagaac
     3301 agccggtaga aggcataaag gagtataaaa gctacattta ccttcaagaa gtaggcaaat
     3361 tccggtgtca tggcattatg tatttaacag tttattctcg tcctttttca atcatatcga
     3421 taatctcttt caactcatcg gtcgatatct tctgttcctt agcaaaaaag gagaccattt
     3481 ccttgtaaga attctcgaaa tagttgttca ccacacttcc cataaacgtc cgtttatatt
     3541 cctcctgtgg gatcagcggc ctgtattcgt aagtatttcc gtaacgtttc gctttcacgt
     3601 atttcttacg ttccagattc ttcacaatag aagcgagtgt cgtataagga ggcttaggct
     3661 cttcatactt cgccaggatg tctttgataa aacacggctc gatctgccag atccagcgca
     3721 ttacatcctc ttcctgtctt gttaatcttt ccatgtttct atattatttt tacgatcgca
     3781 tcgcaaatct acgaatacat cgtaaatacg caagaaataa tgcgttaatt tgtattaata
     3841 attaataatc catcatctat tcgctgcata cgccaaaaag gaatttatct ataagcagcc
     3901 acaccaaaac attccccccc tatattaatt aatgatttta tatactccaa gggaacattt
     3961 tttaagcatg ggatttcact tttttcgacg ataaaaagta tttgaattag cagtttttac
     4021 atgtaatctg tatagtttag aaataaccaa cattttttga caaaatagct attagaactt
     4081 aacatatatt atccatgaaa ggcttgacaa acaagcttgg ttagtgtact tttgtattgt
     4141 ggttttttca taatagtatt agatttaagg ttaacaaagt tggttagggg ttgtcgagat
     4201 gacaatcctt aattttttat atacctgcct cttcctttgc atatattgtt tccggtcata
     4261 ttttcatatt tttgtagcgc tttttatagt acgccactga taaaaaagtc ttacttttaa
     4321 gccgcataat tgataaggaa tctatataaa tacaatatca tgaaaatgct atcttttatt
     4381 ttggtactcc ttttaggggg gggtatgcct gccgggaatc ttttggcttc agacaaagaa
     4441 caaaatcctc attacattac agtgaagaac agtcgggacc tgcaagccta tttccggtat
     4501 gctcccgatc gcccgattgt aatcagcgga catcgtggtg gaatgctaga cggctatccg
     4561 gagaactgca tcgaatcatt cgaaaagacc ctgtcctata tggaatcgtt tttcgagata
     4621 gacccacgtt tgacaaaaga tggaataatc gtattgatgc acgacgaaac catcgaccgg
     4681 acaactactg gaaaaggaaa ggtttcagat tacacttatg cagaactgca acaattcaat
     4741 ctggtggacc gaaacggcaa cgtgacaacc ttcaaaattc caactttaaa agaatgcctg
     4801 gaatggagca aaggcaaaac aatcctgaat ttggatatca aggatgtacc tttagaagtt
     4861 atggctgatt ttatagaaac agaaaagcct gttaacgtaa tatacacggt acataacgcc
     4921 ggtcaagccc gctattatct tgaccggaaa ccggatgcga tgttttcttg ctggtgtaag
     4981 aatcgggaag aattcgataa ttatgaaaaa gccggcatcc cctggaaaca ggtaatggct
     5041 tatgtcggtc cgaagatgga gcctgaacag caaccactgt atgacgctct gcaccgtaac
     5101 ggagtcatgt gcatgatttc cgttgctccg acacatgatc gcgcgaaaac ggaaacagag
     5161 aaaaccgccg gttaccagtc agagatcagc actcgtcccg acgtgatcga aacggactat
     5221 ccgtacctgt ttcaaggact cgatttaaca aaatagcgca gtttaaagga ctctttatag
     5281 ccgattaaaa tctttttgct atttatgctc atctgattaa caagtattag cgacaaaatg
     5341 cttgacaaac gctcttgacg agtgtatctt tgcaatgtgg ttttttcata atagtattag
     5401 atttaaggtt aacaaagttg gttaggggtt gtcgtgagac agcctttaat tgtttataga
     5461 ggttccgttt cttctcccac atacaaatcg tatacgaaaa agccggtcag gacagcttat
     5521 agagatttcc cggcaacgct tttaccttcc cgtttatttc cagttcgaac aatagcatag
     5581 agagttgatg taccggcatc tccaacactg aggcaagctc gttgatatgg atctcattcc
     5641 gcgttcgcat aatggctaaa accggatttt gttccgaggc ggaaaacagc tccatttgaa
     5701 cgggagtagc cgcagcttgg atatcccaac aaagagcgga gagcagatcg tccgcagaag
     5761 tgatcaggcc ggctttgttt tgtcggatca aattgttgca tcctttggaa tggctgtcac
     5821 cgacgcgccc tggaaagcta tagacatctc ggccataaga gaatgcaata tcggcagtta
     5881 ccaaagagcc tcctttttca gccgattcaa ccacgatcgt acaatccgag attccggcga
     5941 caatccggtt ccgccggagg aaatttggac ggtctggttc tgtgccgctg ggaaaatcgg
     6001 tcaacagacc gcccgattcc agcatttcga cagccgtatt ccgatggcag gaaggataga
     6061 tacgatccaa gccatgcgcc agcacagcaa cagtcggaag tcggttgtac aaggcgttcc
     6121 ggtgggcaca gatatcgatg ccgtaagcca atccactcac gaccaacaag tccgggatca
     6181 cttttgccaa gtcttttata agggattcgg taagctcccg gccatattcg gtcgcgttgc
     6241 gagtacccac aatactgatg atacgggtta catcaaggtc agtatttccc ttaaaataga
     6301 aaagtatagg ggcatccgga cattctctca tgcgcaccgg ataatctgta tcagtcagat
     6361 aataacagga aatattgttt ttctcaataa aagccaactc tttttccgcc cgttgcaaga
     6421 tttccggacg tttgatttcg gcagcaatat tgctgccgat accagggatc cttcctaaca
     6481 actgttgctt ttcagtaaac acagcctctg cttctcccaa agcctgcagg agatggcgcg
     6541 ccaggatatc tcccacgccg tttatcatag taaggccgat ttggtaaatc cgtttgtcag
     6601 tcatgtatgt tctattcttt ttagcatttc gtcgaaatat tcaccgcgtg tcaactttcc
     6661 gttctcaacg ataaccgact cgacgattcc tttcgtcgcc aatgcattgt cagaagccct
     6721 atatatatcc tgctcgaata cgagcttgac tcctttttta tagacattga ggcaagagat
     6781 atagctgtcg ccgctcctga gcgaggtctt atactggatt tctacccgcg atacaaatcc
     6841 gtcaacccct ttttcgtgca tcttcccgaa gttctcacca agcgactcca agaattcatg
     6901 tcgagtatgt tccatataat gctgataatt ggagttgttg accactcctt gcaggtcgca
     6961 ttcgtagtca cggaccttgt ctgtcagttt aaaaatatac tctttcatta ttcaaatacc
     7021 ttttcaagtt gcaccttttc cattttatac aatcggtcag acggccgaat cttctcgttc
     7081 accttgagag agaaccgctc acctttaacg gtctcgtcca ccggcttcaa gtccacacgg
     7141 atttcttcta tcgtttgcat aaccgcaccc gttgtcggtc cggtaatcag gatctcatca
     7201 cccactttca ggttaccgga ttccatttcg aactccgcca cgccgatctt gtcgaaatat
     7261 ttgattcctt tggcaacata cactttcttc ttagtcgcac cagagccata tttactactc
     7321 cactcaccca accgttgccc caaataatag ccgtcccaga atcctcggtt gaacacactg
     7381 cgcaggcgtt cgtcccaagc ggcaaccttc ttttcatcga acgtgtcatt gcaataggca
     7441 cacacagctt ccttatagca ttcggtcacc agacggacat attcgggacc gcgagcacgt
     7501 ccttcgatct tgaatacccg tacacctgca tccatcatct tattcatgaa atgaattgtc
     7561 ttaaggtctt taggcgacat aatatactgg ttttcgatat ccagttcgat attgctgtct
     7621 ttatctttta ccgaataagc acgccgacaa atctgcatgc aagctccccg gttggcggaa
     7681 gcgttcattt cgtgcaggct caggtaacat ttaccggaaa tggccataca gagagctccg
     7741 tgggcaaaca tttcgatacg gaccagttct cctttcggtc ccgtaatctg ctggtcgacg
     7801 atctgccgat agatttcatg cacctgtttc aaattcagct cacgcgccaa gacgacaaca
     7861 tcggcaaaac gggcatagaa tttcagtgct tccgcattgg aaatgttgag ctgtgtggaa
     7921 agatgcacct cctgtccgat gctgttggca tagttcatag ctgccacatc ggccgcaatg
     7981 atcgctgaaa cttccgcctc tttcgctgca tcgataatct cgcgcatcag aggcaggtct
     8041 tccccataaa taaccgtatt gacggtcaaa tagctcttaa taccgtgctc acgacaaagc
     8101 gcaacgatct tgcgcaaatc gtctgtcgta aagttattgg aagagcgcga acgcatattc
     8161 aatccttcga taccgaaata gatagaatcg gctccccctt ggatagccgc catcagtgat
     8221 tcgtacgaac cgacaggcgc cattatttca aaatctttct cgttcaagtt cttatacatt
     8281 tactggttcg ttcgcaaagg taggaataat atccgagaag aattgcatgg gtatccgttt
     8341 ctcagagcat caaaatcgtg atcaaatacc attttctata aagatttgca aaacaaccat
     8401 catactgtca ttgttgtcct ttagaatctg ttattcaata ccttaagaca tgatagtttc
     8461 tatttttaac tatcatacta ctatcatgca actatcatga tttcagctta tcattttatc
     8521 tatatcattg acagtatgac atttgtactt tttattgatc aattactaca ttttttagta
     8581 gatatccttt tatccctgtt tttagcagga aatcagtacc tttgtccccg tcattgataa
     8641 tataaatatg aaaataggta caatagattt aggcgaacgc cccgtcttct tagctccgat
     8701 ggaagacgtt acagatattt ctttccggtt gatgtgcaaa cgttttggtg ccgatatggt
     8761 ttataccgaa ttcgtttcag cagacgccct gatccgcagt gtaaataaaa cacagcaaaa
     8821 gctgaacgtg gcggatgaag aacgtccggt cgccatacag atatatggcc gtgatgttcc
     8881 gacaatggtc gaagccgcgc aaatttgcga agccgctcat ccggacattc tcgatatcaa
     8941 tttcggttgc cctgtcaaac gagtggcagg caaaggagca ggcgccggca tgctgcgcaa
     9001 tattccactg atgctggaca tcacccgtga agtcgtcaaa gcggtgaaca tccctgtcac
     9061 cgtaaagacc cgcttgggct gggatgccga caaccggatc atcgtagact tggccgaaca
     9121 gttacaggat tgcggtatcg cagccctttc catccacgga cgtacccggg cacagatgta
     9181 cacaggagag gcagactgga cactaatcgg cgaagcaaaa aacaatcccc gcatacaaat
     9241 tcccatcatc ggcaatggcg atgttacttc cgccgaaatc tgcaaacaac gtttcgaaca
     9301 atatggcgtg gatgccgtta tgattggccg gggcagcata ggccgcccct ggattttcag
     9361 agaagcgagg cattacctgg atacgggcga gacattgcct gccgaatctt tctcatggta
     9421 tctggacata ctgaaaaagc aggtggaaca aagcgtggaa cgtttggatg agcgccgggg
     9481 aattctccac attcgccgcc atttggctgc aactccgctg tttaaaggta ttgcagactt
     9541 caagcagaca cgcgtcgcca tgctacgtgc ggaaacagtg gaagcattat tcgacattct
     9601 ggattccatc cccgacaaat ttcatacagg atacggattt caaagcgact ctcaagtgtc
     9661 agaatcgatc gattgttgat ataataacag tgtgaatccg cacacagtat caattttaaa
     9721 acaaaaagta gcaaatttgc aataaaatgt aattacaaac tcttgcgtat tcagtaaata
     9781 tactttatat ttgcagtgag tttttttcat agtattttag atctaaggtt aacaaagtct
     9841 ttgcagagag ggaatcgaga gactgtttca ctggaaagca acaaaaaagc cgcatccatt
     9901 tttattatag ggagtgcggc ttttttgtgg gtttgaacga acataaagaa agcccgttgc
     9961 caatggcaac gggcttttcc atatacatat atataatgta ttagtcttgt aacttagcag
    10021 agatgaactc gcggttcaag cgagcgatgt tgctaacgga gatgttcttc ggacattcca
    10081 tttcgcaagc gcgggtgttc gtacagttac caaagcccag ttcatccatc ttagcaacca
    10141 ttgcttttgc acggcgagca gcttccacct taccctgagg caaaagagcc agctggctaa
    10201 cctttgcaga gacgaacagc atagctgaac cgttcttaca agcagcagca caagcaccac
    10261 agccgataca agcagcagca tccatagcca aatccgcatc agccttagaa ataggaattg
    10321 cattagcatc aggaacccca cctgtgttta cagaaacgaa accacctgcc tggataatct
    10381 tatcataagc ataacggtct accatcaagt cgcggattac cgggaaaccg gcagaacgcc
    10441 acggctcgat cgtaatcgtc tcaccatcat taaaacggcg catatagagc tgacaggttg
    10501 ttgcacctgt tgccggtccg tgcggatgtc cgtttacata caatgaacac ataccgcaga
    10561 taccttcacg gcagtcgtgg tcgaatacga taggttcttt gccttcgcta accaaacgtt
    10621 cattcaaaat gtctaacatt tccaagaaag aaacactctg attgattttg tcgatttggt
    10681 aagtctcaaa ctgtccttta tctttcggac ctttctgacg ccaaacttta agtgttacct
    10741 ttatatcttt atccatgatt ctaatttttg tgattgatga ttattacttc ttgtagttac
    10801 gtgtttgagg aacaacgaac tgatagttca aatcttcctt cagcataacc gggtctttgt
    10861 cttcaccctg gtattcccaa caagagacgt acatgaactt atcgtcatga cgcatagctt
    10921 cgccttcttc ggtctgatgt tccgtacgga agtggccacc acaagattct gcacggtcta
    10981 acgcatcgtg tgccatcaat gcaccgattt cgataaagtc agccaaacgc aatgccttgt
    11041 ccaattccac gttcaagcta ttggcctcac ccggaatgaa tacattgctc cagaattcct
    11101 tcttcaggtc tttcaacatt tggatagctt ctttcaagcc ttccgcgtcg cgtgccatac
    11161 cgacgtgttc ccacatgata tgtcccagct tacgatggat agaatcgaca gtttctttac
    11221 ccttcacgtt catcaacttc gcgatacggg cgttaatagc cttttctgct tccacaaatt
    11281 caggcaggtc agtgctgaag cgcggaacct ggatctggtc agacagatag ttctggatgg
    11341 tataaggcaa tacaaagtaa ccatcggcca atccctgcat caaagcagaa gcacccagac
    11401 ggttagcgcc gtggtcagag aagttagctt caccgattgc gaacagcccc ggaatagaag
    11461 tcatcaattc atagtctacc cacaaaccac ccattgagta gtgcaatgca ggataaatca
    11521 tcatcggagt ttcgtacgga tcatcgttcg tgatctcttc gtacatatcg aacaggttac
    11581 catatttctg tttaactact tccttaccca gacggttgat agcgtcggag aaatccagga
    11641 atacagccaa gcccgtgcta tttacaccga aaccggcatc acaacgttct ttagcggcac
    11701 gtgaagccac atcacgagga accaagttac cgaatgccgg ataacgacgt tccagatagt
    11761 agtcgcgatc tgcttcagga atatccttac ctttttttgt tccggcctgc aatgccttcg
    11821 catcttccag tttcttcgga acccagatgc gaccatcgtt acgcagtgat tcagacatca
    11881 aagtcagctt agactggaag tcacctttca ccggcacaca agtcgggtgg atctgcacca
    11941 tacaaggatt agcaaagtaa gcccctttct tgtagcactg ccatgcagca gaaccgttag
    12001 acgccatcgc gttagtagac aagaagaatg tatttacata accacctgtc gcaacaacga
    12061 ctgcgtgagc ggcaaaacgt tcgatcttac cggtaatcaa attacgggca ataataccgc
    12121 gagcacgtcc gtcaaccttc acaacatcca gcatttcatg gcgtgtgtac atcttcacct
    12181 ttcccaaacc aatctgacgg ctcaatgcag agtaagcacc caatagcagc tgttgtccgg
    12241 tctgaccacg ggcatagaac gtacgggata cctgagcacc accgaatgag cggttatcca
    12301 acagaccacc atattcgcga gcgaatggta caccctgtgc cacacactgg tcgataatag
    12361 agtttgacac ttcagccaga cgatagacgt ttgcttcgcg ggcacggtag tcaccacctt
    12421 tgattgtatc gtagaacaga cgataaaccg agtcaccatc attctgataa ttctttgccg
    12481 cattgatacc gccctgtgca gcgatagagt gtgcacgacg gggagagtcc tgaatacaga
    12541 aattcaatac attgaatccc atttcagcca gagaggcagc agcagaagca cccgccagac
    12601 cagtacctac tacaattatg tccaaacgac gtttgtttgc gggattcacc aatttctggt
    12661 gatttttata atttgtccac ttctcagcca acgggccttg aggaatttta gaatctattt
    12721 gagtcataat gttttatttt caaattgaaa aaataatatc cgaaattaag cacctacacc
    12781 gttcaggtag aagataactg tgataacagc gaataagcca caaataatag tggcaaccca
    12841 tttagagata cattcccaac ggcttaacca aacggtattg ttccagccaa ttgtgtgaat
    12901 cgcagaccag aaaccgtgag tcaggtgaaa ccacagagca acgaaccaga tcagatacaa
    12961 caccgtattc acaacattgc cctggaagta gaaattgata aacgctgcac catcctgcgg
    13021 atgaatgtca ccatgaatac ctgccagttc agcaaacatc atgttgtacc agaactgagt
    13081 aaagtgcaga accatgaaca ggataacgat cacacccaaa acaaacatgt tctgagaagc
    13141 ccattcaaca cctttcggac gagcgttgat ggcataacgg tcgttaccgc gagccttacg
    13201 attctgcaga gtcaagataa tagcatacac gaagtgcacg actacacctg cagccaacac
    13261 caatgtaccg agcaaagcat accagttaga acccagcaaa ccgcaaatca cgttatacgc
    13321 ttcaccagaa aatactgccg caatgttcat acataagtgg aacaccaaga acagaatgag
    13381 aaaaagacct gatatactca ttatcagctt cttcccgata gaagaattaa gtaaccacat
    13441 aagataataa tttaagttat ttaattgtat ttagaaattt cttccaatct atggttatta
    13501 tcgtgcaaag gtatgctaaa tccccatatc acgcaaacga ttaaagaaat atttcatcaa
    13561 ttagaacgct gcttgctggc tggttttatt ttcatcagat atcacaaacg gattgtacga
    13621 aacgaaaaaa tttcgttttt ttgtagccga tacaggcaag gtcttgccgg ataactgatt
    13681 attatttaat tgtcatatta tgaaaactgc tattttttct attggtgttt ttttgatttc
    13741 tctgttctta ggctcttgtc agccttccga aacatcctgt tccgtcgtcg acacggggaa
    13801 agccttggac tataagatag gaaataaact gttgttctct tacaactata ccacggttta
    13861 cccagcccct ggcgttgact cggtctataa acgcagcggt ttcatccatc ctttgaagac
    13921 attgggaggc gaagtgatga ccaattgttc tcccgccgac cattaccatc atttcggttt
    13981 gtggtatgcc tggacgaaaa ccacgttcga aggaaacgag atcgacttct ggaatctcca
    14041 caaaaaacaa ggaacagttc gcttccgcaa cttcgagcac gtatccgaca acggttttgt
    14101 tgcgacactg gaccatgtgg tctaccccga ttctcccgca gaaaaagtag caatgaacga
    14161 acgcctggag atcaacatcg ggacaacatc cttaccaggt tattacatcg actatcatac
    14221 cactatccgc ctcgccagcc ccagcccgat caccatggaa gcttaccgtt atggcggcat
    14281 atgcatccgt acgcgcgaag actggaacga tcagacagcc gaaatgctca cctcggaagg
    14341 cctttcccgc gacgaagctg acggttcgag agcccgttgg tgctattacc aagggaaagc
    14401 cggaaacgaa aaggcctgta tcctaatcgt tgcctcccct tccaacctga actatcctga
    14461 gcctttacgc gtatgggaca aaactgtcaa caagcctgcc ggtgacgtca tgtggaattt
    14521 ctcaccgacc aagcagaagg cattcacctt ggaacccggt aaagaactga gcctgtctta
    14581 ccgcatttat gtattggaca agaacatcaa cgctactacg gcagaagtgc tgtccgattt
    14641 cgaacgtgat tgaatttcta ctaaaacaaa ctgacaattt gcagggcaag gtaaaaggta
    14701 aacaagaaaa ggaaaaaggg cttgttctcc tatatcatca aagacaaggc tcttttatgt
    14761 aaatacagct acaaatcaat gaaaaacacg taataaaact tgcccaacac ccccatgtgc
    14821 ccgcccccga cacccggatc ttacgctctt atagatccgg gtgtcggggg cgggcacatg
    14881 ggggtgttgg tgaaattgtc tccctacttt taccttaaaa tgcttggagt ttatgcaaaa
    14941 aaacagatag atgagcgatt acagatggtg atagaagcgt gatatataaa acaggtatct
    15001 atcactttag atacgcactg attatcaaga ctcacatgac atttagtgat agagtgacag
    15061 atgtttatga aaaaacatcc aagaaatcac cccatcccga ctactgagct tcaataaagt
    15121 tgcactaaaa ttagataaat taacacaggc attgtatttc attgcctatt gcccttttcc
    15181 ctgtttttcg acagatacaa aatcatgttc tgtgctgatg agaatatgca taaccacaaa
    15241 acattcagac aaataggcaa tattataaaa ataagattat tttttgacca cccatacaaa
    15301 gaaagagata taagttctat cagaactatg gtttttaatt atctcatatc cgggtcaaag
    15361 gtatgaaatt ttcatttcgt tgtatgtttt ttatttaaaa aagttcatac tgcactcatt
    15421 tttaacaatt cagacttgca ggctattaac aagcatcaga caatatcaga cttttgaacc
    15481 tttttaagca caagaagtaa tttgcggctt atcattcaac tctatttttg tacaatattc
    15541 acacttatca gatacatttc ttcataaata catgagttct gatagaacta aattataaaa
    15601 acacagaaaa acgctataaa aatatgcaaa atctaatgag catgatctaa t
//
