LOCUS       c00038_gnlPro..        15244 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GGJMJCAO_38.
ACCESSION   c00038_gnlPro..
VERSION     c00038_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 23:40:39
            Original ID  :: gnl|Prokka|GGJMJCAO_38
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15244
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15244
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7995:12238]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7996..12238
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..15244
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15244
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             418..723
                     /locus_tag="ctg38_1"
                     /transl_table=11
                     /translation="MEKTMTLNLRVNPTVKQQAEDVLKQLGIPMATAIDMYLRQITLTG
                     GIPFSLSLPKAPAALNADTMTDDQLHAALQVGIKEIQNGDTVDAASAFAQFREQHR"
     CDS             720..1040
                     /locus_tag="ctg38_2"
                     /transl_table=11
                     /translation="MKQYDVKISHAALSDMEQIYSYIADRLLEPDTAMGQYDRIAEAIQ
                     SLNILPERCALVESEPEHTQGLRQMLVDNYSVFYIVGEDAVSVARVLYSASDLVRRLRR
                     MK"
     CDS             1054..2799
                     /locus_tag="ctg38_3"
                     /transl_table=11
                     /translation="MTAVIYARYSSDNQREESIEGQIRECTAYAEKNGITVVKHYIDRA
                     LSAKTDNRPDFQQMIKDSEKRLFDIVLVWKLDRFARNRYDSAHYEYLLERNHVKLVSVT
                     EPISDSPAGIMVKSMLTGMAEYYSAELSEKVVRGMTENVLKGKYNGGTIPIGFKVDEEK
                     FFQIDPLKAPFVVEAFQRYNDGATMKELMNWLNDSGVTTNRNQKFTYNSVQTLLTNKRY
                     IGENHFKDIVMPDSIPAIVDKDLFEEVQQKIKKNSRAPARHKAEDDYLLTTKLFCGMCG
                     AMMFGECGTGRNKVVHHYYKCATAKRFKTCKKKTVRKEWLEDLVIAETMKLIQDDAVID
                     AIVADVMELQDQENTTLPLLEKQMREVENGIENMLNAIQAGVLTNSTKSRLEKLEAQQK
                     ELEVRIAEEKIARPRLSENQVRFWLTRFRKLDPNVKSHRETLINTFVNAVYLYDEKVLI
                     AFNYKDGTKTISFNEIAAKDASEGNGSDLGCFAPPRTPVSNGYRSFCFTCLEKGAARVD
                     SNSCGAVAEDSAKTAQWAVFSSAARAIHTRPPRTPVSEPGTGVSVLSALKRGCKGGFEQ
                     HRPAE"
     CDS             3046..3522
                     /locus_tag="ctg38_4"
                     /transl_table=11
                     /translation="MIYDTLNNLPNYLGVSDNLDTVIEYIMARDITTLPAGRTRIDGDK
                     AVVTVSTVTPQTSDKALFQRHDNHITLETDLDGSELFEVSLAELTPTKPTDEAADTTVG
                     TAGTSIAGMLCEGRFALYLAGEPYKSGLKAQGCGKLKKAVFSIELDPDEEETEE"
     CDS             3542..3781
                     /locus_tag="ctg38_5"
                     /transl_table=11
                     /translation="MGFFAVLAASLFAVFIFTVFGGYSLLLWCQQSLWMVVPPALVLAV
                     LVWTFLKMDDKITALQKRVDELEAAQKSTEKLEK"
     CDS             complement(3868..5184)
                     /locus_tag="ctg38_6"
                     /transl_table=11
                     /translation="MDLALFGRYFLDFALLYPSAFLCLASLWEKLRTPRRTACIAAGCI
                     TLLCIGCAALCAVFGLNSNSLLPAIVLVSFWLLRWRVTPEVTVSQTAFLFSISAVMMAV
                     CSLLSTLLNAHTEISNPQTVCLASTALLRLGLAAMLTVLFWFTAVQWSRWLLREYSGEA
                     FWQSAWPLLALYAVFLVYCMPLNPAVVLVGRLKIISVLAVSISLFGIFLLLYEMYRVAR
                     EFTRNARLDRENQLLAMESRRYMELQTYLDNTRRLRHDFRQHLHVIAGLTETGQLEELK
                     SYLHQYESELSEHRPSLCANAAVDALAGYYDHAAGQQSVPVEWKLALPRQLPMPEADLC
                     TILGNLLENALHASQKLPPEQRRVQVMAQMLSPAMLGLVVENRYDGMLKKQQGILHSTK
                     HEGTGIGLVSAETVVHKYNGNLHLETEEQIFRVNVLLNL"
     CDS             complement(5202..5945)
                     /locus_tag="ctg38_7"
                     /transl_table=11
                     /translation="MEKEGVWMALPIAIVEDQAADARRLEELLQQQLPAAECTWFTCGD
                     DFLRAAAEPGLYAVVFLDICMAGTNGIETARRLRQADPEVLIVFVTSSPEYVWDAFPVH
                     PFDYLLKPYQKEKFEHLAAELRRALRCQEPELEIRIARQSIQLPLRKVLYAIARNHYVL
                     ITTEDGEYRAMCSFAQIEEKLTALENFMSCNRGVIINMDKVLRFGEDCIEILDGTRLPV
                     RQKDKCTLLAHFTQYQFRHMRQELH"
     CDS             6517..7983
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_8"
                     /sec_met_domain="OKR_DC_1_C (E-value: 5.3e-12, bitscore:
                     36.3, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 2.1e-123,
                     bitscore: 401.9, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNENKARSRLDQRRAPIYEALERFRQMRVVPFDVPGHKRGRGNPE
                     LTAFLGQQCVGVDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSSVQS
                     MVLTACKRGDEIILPRNVHRSVLNALVLCGAVPVYVNPEVDKRLGISLGMKREQVAKAI
                     KEHPNAVAVLVNNPTYYGICSDLRAIVKMAHDAGMLCLADEAHGTHFYFGGGLPVSAMA
                     AGADMASVSMHKSGGSLTQSSLLLIGPNVHQGYVRQIINLTQTTSGSYLLMSSLDISRR
                     NLALRGRQVFHQVADIAEYAREEINAVGGYYAFGKELCNGDSVFDFDTTKLSVHTLDIG
                     LAGIEVYDILRDEYDIQIEFGDIGNILAYLSIGDRPQEVERLVSALAEIKRRYRTDGSG
                     LLSQEYIDPVVAASPQEAFYAPKKSLPLRETEGMVCSEFVMCYPPGIPILAPGERITKE
                     ILNYIEYAKAKGCSMTGPEDPEILHLNVLA"
     CDS             7996..8853
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_9"
                     /sec_met_domain="Spermine_synth (E-value: 3.6e-54,
                     bitscore: 173.1, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 3.8e-23,
                     bitscore: 71.4, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFWFSEFHTPDVKHSIRVNKQLYSKQSDYQRIDIFETPEFGRVL
                     TLDGNVMLTERDEFIYDEMIVHVPMAVHKEAKDILVIGAGDGGVVRELTRYDRVERIDL
                     VEMDPQVVEACRAYLPGNACRMDDRRVHIYFENALKYIRRCEEEYDLIIVDSSDPFGPS
                     EGLFTREFYGSCFNALKEDGIMVNQQGSPFYAEDASAMQRSHKRIASTFPISRVYQAHI
                     PTFAAGYWLFGFASKKYHPIDDLDAEAWKALNMRTRYYTTKLHIGAFYLPAFLEEMLRE
                     VEEH"
     CDS             8853..9728
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Arginase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_10"
                     /sec_met_domain="Arginase (E-value: 3.5e-77, bitscore:
                     249.7, seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHPNVETFIGCDSSYRAASIVLYGAPYDSTTSYRPGARFGPAAVR
                     HESYGLETYSPYQNADLTDFDVFDSGDLELCFGSSELALADIEARAEEILKDGKFPLLL
                     GGEHLVTLGAVRAAVKKYPDLHIVHFDAHADLRDDYLGAKLSHACVLRRCHELVGDGHI
                     HQFCIRSGDRAEFEFAAQHTEMHKFDFTGLAELTAQLCESKVPVYLTIDLDCLDPSCFP
                     GTGTPEAGGVSFLQLLEAIRTVTKANIIGADLNELAPTLDTTGVSTATACKVLRETLIA
                     LDKGWPGFQV"
     CDS             9768..11027
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_11"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 4.4e-45, bitscore:
                     144.9, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 2e-33, bitscore:
                     105.6, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKVLIIGCGGVASVAIHKCCQVPEVFTEICIASRTKAKCDKLAA
                     ELAPTTATKITTAQVDADKVEEVIALIKAYQPDLVMNIALPYQDLTIMDACLACGVNYM
                     DTANYEPENTDDPEWRAIYEKRCKEAGFSAYFDYSWQWAYAKKFEEAGLTALLGSGFDP
                     GVTQAYCAYAKKHEFDTIDTIDILDCNGGDHGYAFATNFNPEINLREVSAPGSYWENGH
                     WVEIPAMSIKREYNFDQVGDKDMYLLHHEEIESLAKNIPEAKRIRFFMTFGQSYLDHMR
                     CLEDVGMLSTTPVNFNGQEIVPIQFLKALLPDPASLGPRTKGKTNIGCIFTGKKDGKDK
                     TYYIYNVCDHQECYKEVGSQAISYTTGVPAMCGALMLLTGKWTTKGVHTVEEFDPDPYL
                     DALDKYGLPRSESHNPALVD"
     CDS             11027..12238
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_12"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 9.8e-15,
                     bitscore: 44.8, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVRDSRPPFAGLANLSEEQLHRLPTPCYLLDEAQLRRNGEILLG
                     VQQRTGCRILLAQKAFSNFNVYPVLAPYLAGTEASGLYESRLGREELPEKENHVFCAAY
                     RTDEFEELLQYADHIVFNSPSQLAKFGPAAKAAGKSIGLRINPECSTQEGHEIYDPCAP
                     GSRLGTTRAQWDAAVAAHPELPALLDGLHFHTLCEQDADALAVTLAAVEKKFADLLPRM
                     KWLNFGGGHHITRPGYALATLENCILSVRQKYGVQVYLEPGEAWALNAGYLVTTVLDTL
                     RNGDTSLAILDMSAACHTPDVIEMPYRPPLLDAGEAGEKAHTVRLGGPTCLAGDIIGDY
                     SFDAPLAEGDKLIFGDMAIYTTCKNNTFNGMPLPPIWLLGADGNCRELVHFGYQDFKMR
                     LGAQ"
     CDS             complement(12254..12412)
                     /locus_tag="ctg38_13"
                     /transl_table=11
                     /translation="MDCKRVTVIRIGPVISTRMKALHGNVWCFFVLSAVHLTSPFMKKA
                     FVAARRP"
     CDS             12903..13772
                     /locus_tag="ctg38_14"
                     /transl_table=11
                     /translation="MALDYFYGQVGELFSFYRIPKALFLESRFQNLSTDAKTLYGILLD
                     RMSLSAKNGWLDEQGRVFIIFTIEDVKRALCCADNKATKLLRELEEFGLIERKRRGLGR
                     PSLVYVKNFSAESSKSIFQNRDFHDSGGFKSASQDPAKSRCNKTEENSTEKSETYPFYS
                     EEDDGMSKHEQLEEYFSQSLELDILLRLCPDDEDTIYQIVDLLVDTCATNRKMLRIAGD
                     DKPAEVVRSRFMKLNADHIRFVLKCLAENSSPIRNMKQYLLASLYNAPTTMQLSYQNQT
                     NHDLANRR"
     CDS             13769..14605
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CbiA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_15"
                     /sec_met_domain="CbiA (E-value: 9.7e-27, bitscore: 83.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VIKISKKATTIAIVNQKGGTGKTTTCENLGIGLAMEGKKVLLVDA
                     DPQGSLTISMGWQQPDELPTTLSTLMQKAINDQSIPPGEGVLHHAEGVDLIPANIELAG
                     MEVSLVNCMNREKMLKQVLDSAKREYDFILLDCTPSLGMLTVNALAAADTTLIPVQAQY
                     LSAKGLEQLLQTVQKVRRQINPKLKIEGILLTITDSRTNYGQQIDNLIRGAYGSKIKVF
                     DQTIPRSVRAAEISAVGKSIFQHDPKGKVAEAYQSLTKEVLANAEKQLKRVAERGR"
     CDS             14562..15242
                     /locus_tag="ctg38_16"
                     /transl_table=11
                     /translation="MPKSSLSVSLKGADDIFSTEESRQEQQREQVQRIPIGELFPFKDH
                     PFKVLDDESMQRTVESVEQYGVLSPLIARPRPEGGYEIISGHRRQHAAQLAGLDALPVI
                     VRQMDDDAAVLLMVDSNLQRENILPSERAFAYKMKLEALKNQGARSDLTSCQVGTKFRA
                     DELLAENSSESARNVQRFIRLTSLIPELLDMVDEKKIAFNPAVELSYLDEAQQRDFLEA
                     MNDTQ"
ORIGIN
        1 agtatggcag ctcaagacac actatggagt tttgatttgg ctgctcgttt tcttactttc
       61 gtttattatc ggaatgcttg ttgaaaagaa aaatcattgt taaaatgcgt agttaataat
      121 agacagccat ctatttgcaa gtcgcaagta gatggctgtc ggttttatct gtatattcta
      181 attaaaggtc aatcctctaa atctgctatg gtcacagctg agtgagagat aatgctcaat
      241 ctcaccaccc agcacaaact gggcgtactc caaagattta ttctaacgaa tgaatattct
      301 gcgctttaaa caatttaatg acgaatatat tgtgcaatac agagaatttc aatagcggct
      361 tcgcgcttga ttgactcgca acgcaaaatg cgttacaata aaatcgaggt gataaccatg
      421 gaaaaaacga tgacgctcaa tcttcgtgtc aaccctaccg tcaagcagca ggccgaggat
      481 gtgttgaagc agctcggcat cccaatggca accgccattg atatgtacct gcgccagatc
      541 accctgactg gcggcatccc cttctcgctg tctttgccga aagctcctgc ggctctgaac
      601 gctgacacca tgaccgatga ccagcttcac gccgccttgc aggtgggcat caaggagatt
      661 cagaacggtg acactgtgga tgccgcaagc gcattcgcac agttcaggga acaacacaga
      721 tgaagcagta tgacgtaaaa atttcccatg cagccctcag cgatatggag cagatttaca
      781 gctacattgc tgaccgtctg ctggagcctg acacggccat ggggcagtat gaccgcattg
      841 cagaagccat tcagtcactg aacattctgc cggaacgctg tgcgctggtg gaaagcgagc
      901 cggagcacac ccaaggactg cggcagatgc tggtggataa ctactcggtg ttctacattg
      961 tgggcgagga tgccgtgtcg gtggcccgtg ttctgtacag tgcatccgac cttgtgcgcc
     1021 gcctgcggag aatgaagtga aaggggtgtt tgcatgaccg ccgtgattta cgcccgctat
     1081 tccagcgata accagcgtga ggaatccatc gaaggccaga ttcgtgaatg tacggcttat
     1141 gctgaaaaga acggcattac cgtggtcaag cactacatcg accgcgccct ttctgcaaaa
     1201 accgacaacc gcccggattt ccagcagatg atcaaggaca gcgaaaagcg gttgtttgat
     1261 atcgtgttgg tctggaagct cgaccgcttt gcccgaaacc gctatgattc ggcacactat
     1321 gagtatctgc tggaacgaaa ccatgtcaag ctggtgtctg tcacggagcc catctctgac
     1381 agccctgcgg gtatcatggt caagagtatg ctcaccggca tggctgagta ctactcggca
     1441 gagctttctg aaaaagttgt gcgcggcatg actgagaatg tgctgaaagg caagtacaac
     1501 ggcggcacga ttcccattgg ttttaaggtg gacgaggaga agttctttca aatcgacccg
     1561 ctgaaagctc cctttgtggt agaagccttt cagcggtaca acgatggcgc aactatgaaa
     1621 gaactgatga actggctgaa cgacagcggc gtgaccacca accgcaacca gaagttcacc
     1681 tacaacagtg ttcagacact gctgacgaac aaacggtaca tcggtgaaaa ccacttcaag
     1741 gacattgtga tgcccgacag catcccggcc atcgtggaca aggacttgtt tgaagaagta
     1801 cagcaaaaaa tcaagaagaa cagccgcgct cctgcccgtc acaaggccga ggacgattac
     1861 ttgctcacca ccaagctgtt ctgcggaatg tgcggcgcga tgatgttcgg cgagtgcggt
     1921 acgggtagaa acaaggttgt tcatcattat tataagtgcg ccaccgcgaa gcgtttcaag
     1981 acctgcaaga aaaagaccgt ccgtaaagag tggctggaag atttggtcat agctgaaacc
     2041 atgaagctga ttcaggacga tgccgtgatt gatgccatcg ttgcagacgt gatggagttg
     2101 caggatcagg aaaacaccac tctccctttg ctggaaaagc agatgcgcga ggtagagaac
     2161 ggcattgaga atatgctgaa cgccattcaa gctggtgtgc tgaccaattc caccaagtcg
     2221 cgtttggaaa agctggaagc ccagcagaaa gaacttgagg ttcggatcgc cgaagaaaaa
     2281 atcgctcggc cacggttaag cgaaaatcag gttcgtttct ggctgacccg gttccgcaaa
     2341 ctcgacccga acgtgaaaag ccaccgggag acgcttatca acacgttcgt gaacgccgtt
     2401 tatctttatg atgaaaaagt tttgattgca ttcaactaca aagacggcac aaaaaccatc
     2461 tctttcaatg aaattgccgc caaagatgcc tcagagggca atggttcgga tttgggttgc
     2521 ttcgctccac caagaactcc ggtatccaat gggtaccgga gtttctgttt tacctgcctt
     2581 gaaaaagggg ctgcaagggt ggattcgaac agctgcggcg ctgtcgcaga agacagcgca
     2641 aaaacagccc agtgggctgt ttttagcagc gcggctcgcg caatccacac gcgcccacca
     2701 aggactccag tatccgaacc gggtactgga gtttctgttt tatctgcctt gaaaaggggc
     2761 tgcaagggtg gattcgaaca gcatcgaccc gccgaatagt ccggcggggg aaagcccctg
     2821 tgcaacagcg acgaccgctg ccagcggcag aaacagggag gagctgttgg ggctgcggcc
     2881 agcaggatgc gcgtgccgcc caaggcacga tgcagccgct gggagccgcg acccgggttc
     2941 cttttctgcg cggctcgcga catctgcccg cacacatatt gcatctgtcc ctgacctgtg
     3001 ataccataca ggtaactgaa acaacacaga cggaggactt tttctatgat ctacgatacc
     3061 ctgaacaacc tgcccaacta tctgggcgta agcgacaatc tggacaccgt gatcgagtac
     3121 atcatggcgc gggatatcac caccctgcct gccgggcgca cccgcatcga tggggacaag
     3181 gcggtggtca ccgtgagcac cgtcacgccc cagacctccg acaaggcact gttccagcgg
     3241 cacgacaatc acattacgct ggagactgac ttggacggca gtgagctgtt tgaggtaagc
     3301 cttgcggagc tgacgcccac caagccaacc gatgaagccg ccgacaccac cgtaggcact
     3361 gccggtacca gcattgccgg aatgctgtgc gagggacgct ttgccttgta tctggcaggg
     3421 gaaccgtata aatccggcct gaaggcgcag ggctgcggaa agctgaaaaa agccgtgttc
     3481 agcattgagc tggacccgga cgaggaagaa acggaagaat aactgaaagg agactttctg
     3541 tatgggattt tttgctgtac tggctgcaag tctgtttgcc gtatttattt ttactgtatt
     3601 cggcggctat tcgctgctgc tctggtgtca gcagtccctg tggatggtcg ttcctcccgc
     3661 gctggtgctg gccgttctgg tctggacatt tttgaaaatg gacgataaga tcaccgccct
     3721 gcaaaagcgg gtggacgagc tggaagccgc acaaaaaagc acggagaagc ttgaaaaata
     3781 atacagcgcc gcccttcgta gagaaacctc tctgcaaagg acggcgctgc tttttttgtg
     3841 aacgctttca cgttggcctg ccggtggtta cagatttaac agaacattca cccggaagat
     3901 ctgctcctcg gtctccaaat gcagattgcc gttatatttg tgcactaccg tctcggcaga
     3961 taccagcccg atgccggtgc cctcgtgctt ggtggagtgc aagataccct gctgcttttt
     4021 cagcatgccg tcgtaacggt tctccaccac aagccccagc atggcgggac tgagcatctg
     4081 cgccatcacc tgcacccggc gctgctccgg cggcagcttc tggctggcgt gcagggcgtt
     4141 ttccagcaga ttgcccagaa tggtgcacag gtcggcctcc ggcatgggaa gctgccgggg
     4201 cagtgctagc ttccactcca caggaacgct ctgctgcccg gctgcatggt cataatatcc
     4261 ggccagtgca tccacggcgg cgttggcgca caggctgggg cggtgctcac tgagctcgct
     4321 ttcgtactgg tgcagatagc ttttcagctc ctccagctgc ccggtctcgg tcagtccggc
     4381 aatcacatgc agatgctgcc ggaagtcgtg ccgcagacgg cgggtgttgt ccagataggt
     4441 ctgtaactcc atgtaccggc gggattccat ggccagcagc tggttttccc ggtccagccg
     4501 ggcattgcgg gtaaactccc gggcaacgcg gtacatctcg tacagcagca gaaagatgcc
     4561 gaacagcgag atggataccg ccagcaccga gatgatcttc agccgcccga ccagcaccac
     4621 ggcggggttc agcggcatac agtataccag aaaaacggca tagagggcga gcagcggcca
     4681 cgcagactgc cagaaggctt caccgctgta ctcccgcagc agccaccggc tccactgcac
     4741 ggcggtgaac cagaacagca cggtgagcat cgcggcaagg cccagccgca gcagcgccgt
     4801 ggaggcaagg cagacggtct gtgggttgga gatctcggta tgggcgttga gcagcgtcga
     4861 cagcagggaa cacaccgcca tcatcacggc agagatggaa aacagaaacg cggtctggct
     4921 tacggtcact tccggcgtta cccgccagcg cagcagccag aaggagacca gcacgatggc
     4981 gggcaggaga gaattgctgt tcagcccgaa cacggcgcag agcgcggcgc agccgatgca
     5041 cagcagggtg atgcatccgg cagcgatgca ggcggtgcgc ctgggggtgc gcagcttttc
     5101 ccatagggat gccagacaca gaaacgcgct gggatacagc agcgcaaaat ccagaaaata
     5161 acggccgaac agggcaagat ccatggcggc tgctcctttc ctcagtgcag ctcctgccgc
     5221 atgtggcgga actggtattg tgtaaagtgg gcaagcaggg tgcatttatc cttttgccgt
     5281 accggcaggc gggtgccgtc caagatctcg atgcagtcct ccccgaaccg cagcaccttg
     5341 tccatgttga tgataacgcc ccggttgcag ctcataaagt tttccagagc agtaagcttt
     5401 tcttcgatct gcgcaaagct gcacatggca cggtactcac catcctcggt ggtgataagg
     5461 acgtagtggt tccgggcaat ggcgtacagc accttgcgca gcggcagttg aatgctctgg
     5521 cgggcaatgc ggatctccag ctccggctcc tgacagcgca gcgcccgccg cagctcagcg
     5581 gcaagatgct cgaatttttc cttctggtag ggtttgagca ggtaatcgaa ggggtgcacc
     5641 ggaaaggcgt cccatacata ttccggggag gaggtcacga atacgatcag cacctccggg
     5701 tcggcctgtc gtagccggcg ggcggtctcg atgccgttgg tgcccgccat gcagatatcc
     5761 agaaacacca cggcgtataa gccgggctct gctgcggcgc ggagaaaatc atctccgcag
     5821 gtaaaccatg tgcactcggc tgcaggcagc tgctgttgca gcagctcctc cagccgccgg
     5881 gcatctgctg cctggtcctc tacgatggcg attggcagtg ccatccatac accctctttc
     5941 tccattcatt gttcctttat tatagcatac tgcggcggga agggtatctg cttttttgca
     6001 caaaacgccc cattttgcgc gccgagcgcc gccctgcgca cccgcagcgg gcgactgcca
     6061 aaaagttttg gttgacagac ggggcgaatc atgttattct tttgttgatt ttgagagacg
     6121 ccgccttgca gagtcttttc aaagcaattt actcgggacc gcccaaacgg ggctaaggcc
     6181 atacggacag ccgggtccac tgccgaccgg cggcgcaagc tgccattatt gattgagttt
     6241 gaagctcaaa ttttataagt tggttccttt acaaccatga aattgcgcag cctatgcgca
     6301 gacttgtgaa acggtcaata agagtagtaa aagtgtagtt gctatataga ctctcatcac
     6361 cccgtctttt tggatcgcga ataacgcgca gcaccggcac ttacggctgg gtgctttatc
     6421 agcgcggaaa aagctgctcc aagcgcaggt ctgcatattt gtgcagtgtc tgcgcttttt
     6481 tgttgtgcaa aaagaagaac agggacggag gaaatgatga acgagaacaa agcgcgttcc
     6541 cggctggatc agcgccgtgc gcccatttac gaggcgctgg agcggttccg gcagatgcgg
     6601 gtggtgcctt ttgacgtgcc cggccacaag cggggccgcg gcaacccgga gctgaccgct
     6661 tttctgggtc agcagtgcgt gggcgtggac gtgaacagca tgaagccgct ggataacctt
     6721 tgccacccgg tatcagtcat ccgggaagcc gaggagcttg ccgccgatgc ctttggcgca
     6781 gcacacgcct ttttaatggt gggcggcacc accagcagcg tgcagagcat ggtgcttacc
     6841 gcctgcaagc ggggcgatga gatcattctg ccccgcaacg tgcaccgcag cgtgctgaac
     6901 gcgctggtgc tgtgcggcgc tgtgccggtg tatgtgaacc cggaggtgga taagcgcctg
     6961 ggcatttcgc tgggcatgaa gcgggagcag gtggccaagg ccatcaagga gcaccccaac
     7021 gctgtggctg tgctggtgaa taaccccacc tactacggca tctgctctga cctgcgtgcc
     7081 atcgtaaaaa tggcgcacga cgccgggatg ctctgccttg cggatgaagc ccacggcacc
     7141 cacttctact ttggcggcgg cctgccggtt tctgccatgg cggcgggcgc ggatatggcc
     7201 tcagtctcca tgcacaaaag cggcggcagc ctgacccagt ccagcctgct gctcatcggc
     7261 cccaatgtgc atcagggcta tgtgcgtcag atcatcaacc tgacccagac tacctccggc
     7321 agttacctgc tgatgtccag tctggatatc tcccgccgca atctggcgct gcggggacgg
     7381 caggtgttcc atcaggtggc ggatattgcc gagtatgccc gcgaggagat caacgccgta
     7441 ggcggctact acgcctttgg caaggaactg tgcaacggcg attccgtctt tgatttcgac
     7501 accaccaaac tcagcgtcca tacgctggat attggtcttg ccggcatcga ggtctacgac
     7561 atcctgcggg acgagtatga tatccagatt gagttcggcg atatcggcaa catccttgcc
     7621 tacctgtcca tcggcgaccg tccgcaggag gtggagcgtc tggtcagtgc actggcggag
     7681 atcaagcgcc gctaccgcac cgatggctcg ggtctgctga gccaggaata catcgacccc
     7741 gtggtggctg ccagcccgca ggaggctttc tacgccccca aaaagagcct gcccctgcgg
     7801 gagaccgagg gcatggtgtg cagcgagttc gtgatgtgct atcccccggg catccctatc
     7861 cttgcacccg gcgagcgcat caccaaggag atcttgaact acatcgagta cgccaaggcc
     7921 aagggctgca gcatgaccgg cccggaggac cccgaaatct tgcacctgaa tgttctggca
     7981 taaggaggga aagagatgga attttggttt tcagagtttc acaccccgga tgtgaagcac
     8041 agcattcgtg taaacaagca gctctactcc aagcagagcg attaccagcg catcgatatc
     8101 tttgagaccc cggagttcgg ccgggtgctc acgctggacg gcaacgtgat gctgaccgag
     8161 cgcgacgagt tcatctacga cgaaatgatc gtccatgtgc ccatggcggt gcacaaggag
     8221 gccaaggata ttctggtcat cggcgccgga gacggcggcg tggtgcggga gctgacccgc
     8281 tacgaccgcg tggagcgcat cgaccttgtg gagatggacc cgcaggtggt ggaggcttgc
     8341 cgcgcctatc tgcccggcaa tgcctgccgt atggatgacc gccgggtgca tatctatttt
     8401 gagaatgccc tgaagtatat ccgccgctgc gaggaagagt acgacctcat catcgtggac
     8461 tcctccgacc ccttcggccc ctctgagggt ctgttcaccc gcgagttcta cggcagctgc
     8521 ttcaacgccc tgaaagagga cggcatcatg gtcaaccagc agggcagtcc cttctacgcc
     8581 gaagatgcca gcgccatgca gcgcagccac aagcgcattg catccacctt ccccatcagc
     8641 cgggtgtatc aggcacatat ccctaccttt gcggcgggct attggctgtt cggctttgca
     8701 agcaaaaaat accatcccat tgatgatctg gacgcagaag cgtggaaggc gctgaatatg
     8761 cgcacccgct actacaccac caaactgcat atcggagcat tctacctgcc ggcttttctg
     8821 gaggagatgc tgcgggaagt ggaggaacac tgatgcaccc caacgttgag acctttatcg
     8881 gctgcgacag cagctaccgc gccgccagca tcgtgctgta cggtgcgcct tacgattcca
     8941 ccaccagcta ccgccccggt gcacggttcg gcccggcggc cgtccggcac gagagctatg
     9001 gtctggagac ttacagcccc taccagaacg ccgacctgac cgattttgac gtgttcgaca
     9061 gcggcgatct ggagctgtgc tttggctcca gcgagctggc actggccgat atcgaggccc
     9121 gggcagagga aattttgaag gacggcaagt tcccgctgct gctgggtggc gagcatttgg
     9181 tcacgctggg tgcggtgcgt gctgcggtga agaaataccc cgacctgcac atcgtccatt
     9241 tcgacgccca cgccgacctg cgggacgact atctgggcgc gaagctcagc cacgcttgtg
     9301 tgctgcgccg ctgccacgag ctggtagggg atggccacat ccatcagttc tgcatccgca
     9361 gcggcgaccg ggcagagttt gagtttgctg cccagcacac cgagatgcac aagtttgatt
     9421 ttaccggcct tgccgagctg accgcacagc tgtgcgagag caaggtgccg gtgtacctga
     9481 ccattgatct ggattgcctt gatccctcct gcttcccggg caccggtacc ccggaggctg
     9541 gcggcgtaag ctttttgcaa ctgctggagg ccatccgcac tgtgaccaag gctaacatca
     9601 tcggtgcaga cctgaacgag cttgccccca cgctggacac caccggcgtt tccaccgcca
     9661 ccgcctgcaa ggtgctgcgc gagaccctga tcgcgctgga caagggctgg ccgggctttc
     9721 aggtataaat acgaacctac cattttacag ataaaggagt aaccgacatg agcaaagttc
     9781 tgatcatcgg ctgcggcggc gtggcctctg ttgccatcca taagtgctgc caggtgcccg
     9841 aggtgttcac cgagatctgc atcgccagcc gtaccaaggc aaagtgcgat aaactggctg
     9901 ctgagctggc tcccaccacc gccaccaaga tcaccaccgc acaggtggac gcagacaagg
     9961 tggaagaggt catcgccctc atcaaggcct accagcctga cctcgtgatg aacatcgccc
    10021 tgccttatca ggatctgacc atcatggacg cctgccttgc ctgcggcgtc aactacatgg
    10081 acactgccaa ctatgagcct gagaacaccg acgacccgga gtggcgtgcc atctatgaga
    10141 agcgctgcaa ggaggccggc ttctctgcct actttgatta cagctggcag tgggcctacg
    10201 ccaaaaaatt cgaggaagcc ggtctgaccg ctctgctggg cagcggcttc gacccgggtg
    10261 tgacgcaggc ttactgcgcc tacgcaaaaa agcacgagtt tgataccatt gacaccatcg
    10321 atattctgga ctgtaacggc ggcgaccacg gctatgcctt tgccaccaac tttaaccccg
    10381 agatcaacct gcgcgaggtg tccgcccccg gcagctactg ggagaacggc cactgggtag
    10441 agatcccggc catgagcatc aagcgggagt acaacttcga tcaggtgggc gacaaggata
    10501 tgtacctgct gcaccacgag gagatcgagt ctctggcaaa gaacatcccg gaggcaaagc
    10561 gcatccgctt cttcatgacc tttggccaga gctatctgga ccacatgcgc tgtctggagg
    10621 acgtgggcat gctgtccacc actcctgtca acttcaacgg acaggagatc gtgcccatcc
    10681 agttcctcaa ggcgctgctg ccggaccccg ccagccttgg cccccgcacc aagggcaaga
    10741 ccaacatcgg ctgcatcttt accggcaaaa aggacggcaa ggataagacc tactacatct
    10801 acaacgtctg cgaccatcag gagtgctaca aggaagtggg cagtcaggcc atcagctaca
    10861 ccaccggcgt gcccgccatg tgtggcgccc tgatgctgct caccggcaag tggaccacca
    10921 agggcgtgca cactgtcgag gagtttgatc ccgatccgta tctggatgca ctggataagt
    10981 acggcctgcc ccgctccgag agccacaacc cggctctggt ggactgatgc gggtgcgcga
    11041 cagccgcccg ccctttgcgg ggctggcaaa cctgtccgag gagcagctgc accgcctgcc
    11101 caccccctgc tatctgctgg acgaagccca gctgcgccgc aacggcgaga tcctgctggg
    11161 ggtgcagcag cgcaccggct gccgcattct gctggcgcag aaggcttttt ccaacttcaa
    11221 tgtctacccg gtgctggcac cctatctggc aggtaccgag gccagcggcc tgtacgagag
    11281 ccgcttgggc agggaagaac tgccggagaa ggagaaccat gtgttctgtg ccgcctaccg
    11341 gacagatgag tttgaggaat tgctgcaata cgccgaccac atcgtgttca actcgcccag
    11401 ccagctggca aagttcggcc cggcggcaaa ggcagcgggc aaaagcatcg gtctgcgcat
    11461 caacccggag tgctccacgc aggagggtca cgaaatttac gacccctgcg cacccggcag
    11521 ccgtctgggc accacccgtg ctcagtggga cgccgccgtg gcagcgcacc cggagctgcc
    11581 cgccctgctg gacggtctgc actttcatac cctgtgtgag caggacgccg atgcgctggc
    11641 ggtaacgctg gccgcagtgg agaaaaagtt tgcagacctg ctgcccagaa tgaaatggct
    11701 caacttcggc gggggacacc acatcacccg cccgggctat gcccttgcta cgctggaaaa
    11761 ctgcatcctc tcggtgcggc agaagtacgg cgtacaggtg tatctggagc ccggcgaggc
    11821 ttgggcgctg aatgcaggct atctggttac caccgtgctg gacaccctgc gcaacggaga
    11881 taccagcctt gccattctgg atatgtccgc agcctgccac accccggatg tcatcgagat
    11941 gccctaccgc ccgccgctgc tggacgccgg cgaggcaggg gagaaggcgc acactgtccg
    12001 cttgggcggc cccacctgcc ttgcggggga tatcatcggg gattacagct ttgacgcccc
    12061 ccttgccgag ggtgataagc tcatcttcgg cgatatggcc atctacacca cctgcaagaa
    12121 caacaccttc aacgggatgc ccctgccgcc catctggctg ctgggcgcag acggcaattg
    12181 cagggaactg gtgcacttcg gctatcagga cttcaaaatg cgcttgggcg cacagtaaaa
    12241 taaaaagcgt ttgtcacggc ctacgggctg cgacaaacgc ttttttcatg aaaggggacg
    12301 taaggtgaac ggcagataaa acaaaaaagc accacacgtt tccgtgtagt gctttcattc
    12361 tggtggagat taccgggccg attctgatca cggtgaccct cttgcagtcc atgcacggca
    12421 ctctcctggg tgagctaaac cctcactcgt ttggcagcaa caaaaaagca ccacacgttt
    12481 ttgtgtagtg ctttggttct ggtggagatt accgggatcg aaccggtgac ctcttgcatg
    12541 ccatgcaagc gctctcccga accacgcact cacgcacccc cacgcaaagg tgcgaggatg
    12601 gacgatattt ggcgttagaa cgctttattt cgagaaagac acattctcac ccaaaagcaa
    12661 cgctgttgct taaacgagtt tcattgacga tgtatagttt acatcctgtt tctaggtgtt
    12721 gtcaagatgt tttatccccc tttcgacacc aaacaggtta aattcttctt atttattaag
    12781 ctaaaaagcg caattttgat tttcaaaaat cggaattgcg cttttttatt tcaaaaaatc
    12841 tattgcgagg agattttcta caatgtcaac atcttaccaa cactatttca gagcacagcc
    12901 gtatggccct tgattacttc tacggacaag tcggagagct tttctcattc taccgcatcc
    12961 cgaaagcact ctttttagag tcacgcttcc aaaacctgtc aaccgatgcc aaaacactgt
    13021 acggtatcct gctcgaccgc atgagcctgt ctgctaaaaa tggctggctg gacgagcagg
    13081 gccgggtgtt tatcatcttc acaattgagg atgtcaagag ggcattgtgt tgcgcagaca
    13141 acaaagcgac caagctgctg cgggaacttg aagaatttgg tctgattgaa cgaaaacgtc
    13201 gaggcttggg caggccaagt ttggtgtatg tgaaaaactt ttcggcagaa tcgtcaaaat
    13261 caatattcca gaatcgtgat tttcacgatt ctggaggctt caaaagcgca agtcaagacc
    13321 ctgcaaaatc acgatgtaat aagactgagg agaatagtac tgaaaagagt gaaacttatc
    13381 ccttctattc cgaagaagat gatgggatga gcaaacacga acaactggaa gaatattttt
    13441 cgcagtcttt ggagttagac atcctgctcc ggctctgccc ggacgatgag gacacaatct
    13501 atcaaatcgt ggatctgctg gttgacacct gcgccaccaa tcgcaagatg ctgcgcattg
    13561 ccggggacga caagcccgcc gaagtggtgc gcagccggtt tatgaagctg aatgccgacc
    13621 atatccgctt tgtgctgaag tgccttgcag agaacagcag cccgatccga aacatgaaac
    13681 aatatctgct cgcttctctg tacaacgcac ccaccacgat gcagctttcc taccagaacc
    13741 aaaccaacca cgacttagcg aatcggaggt gataaaaatt tcaaagaaag caaccacgat
    13801 tgccatcgtc aaccagaaag gcggcaccgg caagaccacc acctgtgaaa atctgggcat
    13861 cggtctggcg atggagggca agaaagttct gctggtggac gctgacccgc agggcagctt
    13921 gaccatcagc atgggctggc agcagcccga tgaactgccc accacccttt ccaccctgat
    13981 gcagaaagcc ataaacgacc agagcattcc acccggcgag ggtgttctgc accatgcaga
    14041 aggtgttgac ctaattccgg caaacatcga actggcaggg atggaagttt cccttgtgaa
    14101 ctgcatgaac cgggaaaaga tgctcaagca ggtgctggac agtgccaagc gggagtacga
    14161 ttttattctg ctggactgca ctccttccct tgggatgctg accgtcaatg ccttggcagc
    14221 ggcagacacc accctgattc ccgtgcaggc gcagtatctg tctgcaaaag gtttggaaca
    14281 gcttttgcag actgtgcaga aagtccgacg gcagatcaac ccgaaactga aaatcgaggg
    14341 catcctgctg actataacag atagccgcac caactatggg cagcagatcg acaacctgat
    14401 tcggggtgct tacggcagca agatcaaggt gttcgaccag accattcccc ggtctgtccg
    14461 tgctgcggaa atcagcgcag tgggcaaaag cattttccag cacgacccca aaggtaaggt
    14521 ggcagaagcc taccaatctc tgacgaagga ggtgctggcg aatgccgaaa agcagcttaa
    14581 gcgtgtcgct gaaaggggca gatgacattt tctccacgga agaatcccga caggaacagc
    14641 agcgggagca ggtgcagcgg attcccattg gagaactgtt ccccttcaaa gaccatccct
    14701 ttaaggtctt ggatgacgag tccatgcagc gcacggtgga aagcgtagag cagtacggcg
    14761 tgttgtctcc gctgatcgcc cgcccacgcc cggagggtgg ctatgaaatc atctccgggc
    14821 accgccgtca gcacgctgca cagcttgccg ggctggatgc tctgcctgtt atcgtccgtc
    14881 agatggatga tgatgccgca gttttgctca tggtggactc gaatctccaa cgtgaaaaca
    14941 tcttgcccag tgaaagggct ttcgcctaca aaatgaagct ggaagctcta aaaaatcaag
    15001 gtgctaggtc agatttaact tcgtgccaag ttggcacgaa gttccgggca gacgaattgc
    15061 ttgcggaaaa ctccagcgaa agtgcccgaa atgtccaaag gtttatccgc ctgaccagcc
    15121 ttatcccgga actgctggac atggtagacg aaaagaaaat tgcctttaat cccgctgtgg
    15181 agttgtcgta tctggacgaa gcccaacagc gggatttttt agaagcgatg aacgacaccc
    15241 agaa
//
