LOCUS       gnlProkkaOHMGKFPA_31   16736 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OHMGKFPA_31.
ACCESSION   gnlProkkaOHMGKFPA_31
VERSION     gnlProkkaOHMGKFPA_31
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 07:07:36
            Original ID  :: gnl|Prokka|OHMGKFPA_31
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16736
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16736
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[6030:6736]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6031..6736
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..16736
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16736
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             3..77
                     /locus_tag="ctg31_1"
                     /transl_table=11
                     /translation="MKTPEIVVQSRGFTSAIEKLDLFV"
     CDS             complement(133..681)
                     /locus_tag="ctg31_2"
                     /transl_table=11
                     /translation="MSKLIAKNVFQLPKMNLLVLTTSAFLLALDVILYKIAIGPAYFQL
                     SFGFLSMACIGYLYGPIWGGLLEMISDILSFTIFGSGAFQIAFLLTAFLGGFIDGLFLY
                     RKSVNWLSVVMTQILVMIFVSLMMDSWLISVLFGTNFKVLLLGRLARVIIQIPLQVIAI
                     FYFIKALEKRHVFDRMRLR"
     CDS             complement(876..1010)
                     /locus_tag="ctg31_3"
                     /transl_table=11
                     /translation="MIKSILKFCLAATLIVSGVLIGGTVLTAKGIDNLGDKLQDKLHG"
     CDS             complement(1027..1272)
                     /locus_tag="ctg31_4"
                     /transl_table=11
                     /translation="MHWLWVLIIGAIIGAIAGAITNKGKSMGWISNIIAGLVGSAIGEA
                     LLGSWGPQLAGMAIVPSIIGGVIVVAITSFVLTRMD"
     CDS             1558..3072
                     /locus_tag="ctg31_5"
                     /transl_table=11
                     /translation="MLAFKLCKSFLVIYVKRAIKMTEKLTTETGQPWANNEHSQTAGAR
                     GPVLMQDYNLLEKLAHFDRERIPERVVHAKGAGAKGFFELENDMGEYTKADLFNGVGKK
                     TPVILRFSQVAGEKGYPDTVRDVRGFALKFYTQQGNYDLVGNNTPVFFVNDPLKFPDFI
                     HSQKRDPKTNRRTQNMQWDFWAHSPESLHQVTYLMGDRGLPASYRTMNGYGSHTFKWVN
                     QNGEQFWVKYHFISDQGVKNMTAQAAEKAMSQDLDYLQDDLYDAIQEKNYPSWTMYVQI
                     LPYEEGLNYKWDIFDVTKVISHKDYPLIKVGKLTLNENPTNNFTDIEEAAMSPANFVPG
                     IEPSPDKLLQGRLFSYKDAQRYRLGANFEDLPVNKPVVPVHNYERDGYMKINNQGAEVN
                     YEPNALHGPEEVPDAALSPDSVRGETRAQPYRYQVDYTTQAGDLYRLMSEPEQERLINT
                     IKDALGQVTLPGVKKLEIKQFYEADKNYGTRVANALGMNIADIISD"
     CDS             complement(3230..3667)
                     /locus_tag="ctg31_6"
                     /transl_table=11
                     /translation="MIRLYTQSSCHSSRVARQWLEAHGIEFKEKNFSVDSPTVQDLKRI
                     LSLTEHGVDDIISARSKDYPEIAPKLPEMPLNEALKLLCDHPKLLRRPIIISDSKIQVG
                     FNEDDIRQFIPRPVRRLKFNALLSRLDGNTGDHIINKRMVE"
     CDS             complement(4023..4766)
                     /locus_tag="ctg31_7"
                     /transl_table=11
                     /translation="MISVYICEDDPKQLQQIRQIITKVIVDQQLDMSICLACQDPHELL
                     DKVNAQQPQKAIYVLDIALNSDINGIQLASQIRDMGRRSKIIFITTHTELSLMVFQYQV
                     EALDFILKDFPDSLYERFSKVLHVAQDRFQTDENDQDDYVQIKIGETVRSINVKSIIFF
                     ESSTSPHKIVVHLDDGELEYYGLLKDVPDLSPNFYRCHKSYVVNLKRIKSLDKHLRRLT
                     MTNGEKVLCSAQANRYLAKWLAKKS"
     CDS             complement(4759..6021)
                     /locus_tag="ctg31_8"
                     /transl_table=11
                     /translation="MLMIVFQELSIYLIIKSLLRNIFFVRLFDVIFLSVCMLMSYIFLA
                     KLGISFSFLMLMMFIFFTWWYVRVLSGALCITFQVFIWSIMVDHICDILTRLMKVPNGY
                     VVVFVILSVVSLIFLNIVMDRTNFSPTFSNQSLNRITALLLMIIYLYIMLSEGLENQFQ
                     VILSNLIILSVVMGLVLVIYNEYLKNVRAKYEVQKQRIQIQNDTRYMNEIEAHYNELRR
                     FRHDYQNMLISIDEYLKTDDLEGLQEYYQKNLAPVSNRVLKEKYNLEDLSRVKVKSIKS
                     ILFSKLSYAQSQEIEVHFDLKEPLIDITVNELDLDIALGIMLDNAIEASVGHADGEIMS
                     AIFIEKNSTVFLIQNNVFEQLPPLWKLKEAGYSTKGKNRGIGLNSLSKIVNRNENMILE
                     TRVLGAVFLQRLTVKRVSQND"
     CDS             complement(6031..6159)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_9"
                     /sec_met_domain="TIGR04223 (E-value: 2e-08, bitscore: 25.3,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEKMYKVLSHLFQYVGTKQLVMCCHGILFETKIPDELKSKD"
     CDS             complement(6140..6736)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_10"
                     /sec_met_domain="AgrB (E-value: 1.6e-35, bitscore: 113.1,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKPEQKLLLYKLSDRLFAAIQKNLQLERRQALLVKLGIDTVLNV
                     IPKLIITIILALLLHELVPVLVFMGSFLVLRGFAYGRHLKSDLLCTILTIFVFVGVPYV
                     IETGISEVYRLLLSLIFVIIISIFAPADTVKNPITSKSLRKKLKRRAIGLSLILSLLQI
                     VSNNYFGTIILIAMALAALLLMPYERRENYERKNV"
     CDS             complement(7104..9218)
                     /gene_functions="other (smcogs) SMCOG1223:ATPase (Score:
                     962; E-value: 4.5e-291)"
                     /gene_kind="other"
                     /locus_tag="ctg31_11"
                     /transl_table=11
                     /translation="MANFYGNDPFFNNDMDDVFNQLFRRMDNQNSERARYLVNGQSLTP
                     DEFAQYRATGKLPQNNKTIEVSKDGKQAVKKGGILEKLGTNLTEQARDGLLDPVIGREN
                     EIQETAEILSRRTKNNPILVGDAGVGKTAVVEGLAQAIVAGKVPETIQDKEIYSIDLSS
                     LEAGTQYRGSFEENIKQLVKEVKAAGNIILFFDEIHQIIGTGATGGEDGGKGLADIIKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNDVVINEPTAADTLRILQGVKKLYEKH
                     HHVVLPDDVLKAAVDYSIQYIPQRTLPDKAIDLIDMTAAHLAAKNSQTDVETLDQRVKK
                     LEATKEAAVKSEDFTKAADIKKSIEETKQKIKKTDQKEKITATIDDVAQSVERLTGIPV
                     ADMGANDIEHLKNLDKRLKSKVIGQDEAVEMVAKAIRRNRAGFSEGDQPIGSFLFVGPT
                     GVGKTELAKQLALDMFGNKNAIIRLDMSEYADRTAVSKLIGTSAGYVGYEDNANTLTER
                     VRRNPYSIVLLDEIEKADPQVLTLLLQVMDDGRLTDGQGNVINFKNTIIIATSNAGFGN
                     EALSGDKQRDQSLMDKLAPFFRPEFLNRFNGIVEFSHLTKQDLSQIVDLMLADVQKTLA
                     KKSIKLEVTKAAKDWLMEQGYDEAMGARPLRRVIEQQIRDKVTDFYLDHLDVKNLKADL
                     VDAEIVISAA"
     CDS             complement(9609..9842)
                     /locus_tag="ctg31_12"
                     /transl_table=11
                     /translation="MSVENNYCKLQQAHDQKCRVSLRFYKTNGQMAETVGYVTTIVPKA
                     IAFMAITGHRHLIQLNRIITVSLQSQDRRYVM"
     CDS             complement(10479..10835)
                     /locus_tag="ctg31_13"
                     /transl_table=11
                     /translation="MLAIGAGAQGIYVSNHGGRQLNGGPASFDVLHEIAQAVNGRVPTI
                     FDSGVRRGSHVFKALANGADLVALARPIIYGLALGGAQGVASVVSHLNDELLIDMQLAG
                     TKTIEDVKRAKLLR"
     CDS             complement(10848..11579)
                     /locus_tag="ctg31_14"
                     /transl_table=11
                     /translation="MTVINGYEQSDREQKLTILNLPSLEAAAKKIIPSGGFGYISGGSE
                     DEWTLKQNTMAFNHVQIVPRALTDMEQPSTQTQAFGIDLKTPIMMAPAAAQGLAHARGE
                     AATAEGMAQVGALMAQSTYSSTSIADTAAAGKGAPQFFQLYMSKDWNFNQSLLDEAVKA
                     GAKAIILTVDATVDGYREADIINNFQFPIPMANLTKFSEGDGKGKGIIEIYAAAAQKIS
                     PADVRRITEYTNLPVIVKGIQ"
     CDS             complement(11606..13360)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 471.4;
                     E-value: 6.8e-143)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg31_15"
                     /sec_met_domain="TPP_enzyme_N (E-value: 2e-41, bitscore:
                     132.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3e-32, bitscore:
                     102.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEMTKIKAGQALAQVLVDWNIDHIYGITADSINNTVDGFYQEKDH
                     LKYIQVRHEEVGALAAAADAKLTGTIGVSFGSAGPGAVHLLNGLYDAKMDHVPVLALVG
                     QSATSIMNTNFFQEMNQDPIFADVAEFHKQVTTAEQIPYVVDEAIRSAYATRSVSVVII
                     PDDLSGQDIEFDGFKTASLSGSQQVLMPKLDDVQQTIAALKAAQHPVLWIGKGAYNARQ
                     EVIAVSEKFSLPVLSTAPATGIMPTDHPNFMGSRGRLGTKPAFEVSQAADLVLFVGTNF
                     PFARYLPQGIKFIQVNNNLADLGKQHDADITVLADAKEFFQALLQSEVTIKPTKFLKAA
                     QRDKQNWNRWLKTIATDDQGGLTAEGVLEAIKDNATDDAVFGLDVGNNTEWAIRQLPLN
                     KQQTFTMSAWYGTMGFGLPAGLAAQLNYPKKQVWSISGDGGYAMVMPDLLTEVKYHLPV
                     INVVLENKVLGFIQHEKLLANQAPYGIDLIGADWAKMADNMGAIGFKVTNLKELKATFQ
                     KVTQLQQNGNQLPIVIDAKIKNVDPIDTSFVPVDPENFDADTIAKYRERYGIAEADQPA
                     LSQLLNEL"
     CDS             complement(13442..13867)
                     /locus_tag="ctg31_16"
                     /transl_table=11
                     /translation="MANTQLSDATHIMAYIALHTDDQLKSEHIASSLNTDPTMVRRMMS
                     KLRKAGLLTSVRGVARPTLACSPNDITLKDIYVAVVAKRNFLNVDHNTSETCPVGSVIP
                     RVMEKYYCDIQNSAEARMSRVTLQDIIDDISAVQQQA"
     CDS             complement(14040..15851)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 494.2;
                     E-value: 8.6e-150)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg31_17"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.3e-44, bitscore:
                     142.8, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-38, bitscore:
                     123.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVMKQTKQTNILAGAAVIKVLEAWGVDHLYGIPGGSINSIMDALS
                     AERDRIHYIQVRHEEVGAMAAAADAKLTGKIGVCFGSAGPGGTHLMNGLYDAREDHVPV
                     LALIGQFGTTGMNMDTFQEMNENPIYADVADYNVTAVNAATLPHVIDEAIRRAYAHQGV
                     AVVQIPVDLPWQQIPAEDWYASANSYQTPLLPEPDVQAVTRLTQTLLAAERPLIYYGIG
                     ARKAGKELEQLSKTLKIPLMSTYPAKGIVADRYPAYLGSANRVAQKPANEALAQADVVL
                     FVGNNYPFAEVSKAFKNTRYFLQIDIDPAKLGKRHKTDIAVLADAQKTLAAILAQVSER
                     ESTPWWQANLANVKNWRAYLASLEDKQEGPLQAYQVLRAVNKIAEPDAIYSIDVGDINL
                     NANRHLKLTPSNRHITSNLFATMGVGIPGAIAAKLNYPERQVFNLAGDGGASMTMQDLA
                     TQVQYHLPVINVVFTNCQYGFIKDEQEDTNQNDFIGVEFNDIDFSKIADGVHMQAFRVN
                     KIEQLPDVFEQAKAIAQHEPVLIDAVITGDRPLPAEKLRLDSATSSAADIEAFKQRYEA
                     QDLQPLSTYLKQFGLDDLQHQIGQGGF"
     CDS             complement(16222..16599)
                     /locus_tag="ctg31_18"
                     /transl_table=11
                     /translation="MMTKERIIFSTKVLEIGAESADFKSIGMAVLFGDEAPDALRPSCF
                     IIEVVPISEQITAGMKLEVDNQVYQITAVGGEVQTNLGRLGHTAISFTGAKEAKLPGTL
                     YVEQGDYPDFKVGSVVRIIAE"
ORIGIN
        1 atagtaaaac ccccgagatt gttgtccaat ctcgggggtt cacttcagca atagaaaagt
       61 tagacttatt tgtttaacga ttgtagcgcg tttcataccg tgttcaacct ctttttgtag
      121 catccatcga tattatctaa gcctcattct atcaaaaacg tgtcgttttt ctaacgcctt
      181 aatgaagtaa aaaatagcaa tcacctgtaa tggtatctga atgatgacgc gtgccaatct
      241 tcccaacaat aacactttaa aattagtgcc aaatagcact gaaattagcc atgagtccat
      301 catcaaacta acaaaaatca ttacaagtat ttgcgtcatc acaacggata accaattgac
      361 tgatttacga tataaaaaca aaccgtcaat aaatccccct aaaaatgcag ttaacaaaaa
      421 ggcaatctga aacgcgccgg aaccaaaaat agtaaagctt aatatatcgg agatcatctc
      481 caagagacca ccccaaatgg gaccatatag ataaccaata caagccatag acaaaaagcc
      541 aaaagataat tgaaaatacg ctggtccgat agcaattttg tataaaataa cgtctaaggc
      601 caataagaaa gccgatgtag tcagcactaa taaattcatt tttggcaact gaaaaacatt
      661 tttcgcaata agtttagaca taggccaatc ctcttttttt gattttaatc ataccctcat
      721 tcttaataaa agtaaatatt acttttattc gattgaaggt agtttaaaat cgtcgctctt
      781 gatttagttc cttgaactca atgatattac tcatactaaa agccactaac aggtcaacta
      841 gtacacccat cagtggctca ttgtaaaatt aatttttatc catgtaactt atcttgtaat
      901 ttatcaccca agttatcaat tcccttagca gtaagtacgg tcccaccaat aagaacacca
      961 cttacgatta aggttgcagc taaacaaaac tttaaaatgc ttttaatcat cgcaatcatc
     1021 tccttactaa tccatccgtg tcagaacaaa tgaggttatc gcaacaacaa tcacaccacc
     1081 aataattgaa ggaacaattg ccattccggc taattgtggt ccccatgatc ccaaaagagc
     1141 ttccccaatt gcagatccaa ccaatccggc aataatatta ctaatccacc ccatcgattt
     1201 acctttatta gtaatagcac ctgcaattgc accaataata gcaccaatga tcaaaaccca
     1261 taaccaatgc ataaaatccc tcctagactt attaaaccgc ttaaatacaa taatagaatt
     1321 acacgaatat ttaagccgat tcataaatga ttacttctta taattatcat tttacaatta
     1381 tcgataatga tagacaaata taacacatta tttaataaat gggtcgctac tatttctcat
     1441 gtgacgattc cgggtggcct agaaaatatc aaacagcttg atagctgatt aaaattaaac
     1501 tacgccacat gaacgattaa cttaactgtg cataatgatt gaagtcactc tgttaaggtg
     1561 ttagcgttta aattgtgcaa gagctttctt gtaatttacg tgaaaagggc gattaaaatg
     1621 acggaaaaat taacgacgga aaccggccaa ccatgggcta acaatgaaca ttcccaaacg
     1681 gcaggagctc gtggtcccgt attaatgcaa gactataatc ttttggaaaa actagcccat
     1741 tttgatcgtg aacgaattcc agaacgggtc gttcatgcta agggggccgg agcaaaaggt
     1801 ttttttgaac ttgaaaacga catgggggaa tatactaagg cagacttatt taatggtgtc
     1861 ggtaagaaaa ctcccgtaat cttaaggttc tcacaagttg ccggtgaaaa aggttatcct
     1921 gacaccgttc gagacgtgcg cggttttgcc ttaaaatttt atactcagca aggcaattat
     1981 gatctcgttg gaaacaacac accggtcttt tttgtaaacg accctttaaa atttcctgac
     2041 ttcatccatt cacaaaaacg ggatcctaaa acgaaccgtc gtacgcaaaa tatgcaatgg
     2101 gatttttggg ctcattctcc agaatcattg caccaggtca cttatttaat gggcgaccga
     2161 ggtcttcctg cgtcctatcg aaccatgaat ggttacggtt cccatacttt taaatgggtt
     2221 aatcagaatg gcgaacagtt ttgggttaag tatcacttca tctcagacca aggcgttaaa
     2281 aatatgactg ctcaagcagc tgaaaaagca atgagccaag atttagatta cttacaagat
     2341 gacttatatg atgcaattca agaaaaaaat tacccatcat ggacgatgta tgtccaaatc
     2401 ttgccatatg aggaaggtct aaactataaa tgggacattt ttgatgtcac taaagtcatc
     2461 tcccacaaag actatccact aattaaagtc ggcaaactaa ctttaaatga gaatcccact
     2521 aataacttta ccgatattga agaggcggcc atgtcgccag caaattttgt tcctggtatc
     2581 gaaccatctc ccgacaaatt actacaaggt cgcctattct cctataaaga tgcacagcga
     2641 tatcggttag gtgccaactt tgaagattta cccgtgaaca agccggttgt tccagttcat
     2701 aattatgaac gtgatggtta catgaaaatt aataatcaag gtgctgaggt caactacgag
     2761 cctaatgcac tgcatgggcc agaagaggtg ccggatgccg cactttcacc tgattctgtt
     2821 cgtggtgaaa cacgcgcaca gccttatcgc tatcaagttg attacacaac tcaagcaggc
     2881 gacctatatc gcttaatgtc agaacccgag caagaacgct taattaatac tatcaaagat
     2941 gcgttaggcc aagttacttt gcctggtgtc aaaaaactcg aaatcaagca attttatgag
     3001 gccgacaaaa actacggtac acgcgtggct aatgctctgg gaatgaatat tgctgatatt
     3061 atcagtgatt aatattttga ccggatgtta tccagcgcga tattattttt gttataaaga
     3121 atgatgatgc cgtctcatgg ttattaacta aagagcgaca ggttagactc atatcgtgta
     3181 agtctagctt gtcgctcttt aattaacaaa aaatcttaga tatagcttac tactcgacca
     3241 tccttttatt aataatgtga tcccctgtat taccatctag acgactcaac aatgcattga
     3301 actttagtcg ccgaactggt cgtggaataa attggcgaat atcatcttca ttaaagccaa
     3361 cttgaatttt actatcacta atgatgatag gccgacgtaa caacttcgga tgatcacaca
     3421 acaatttaag tgcctcattc aatggcattt cgggtaactt aggcgcaatt tcaggatagt
     3481 ctttagatcg agctgagata atatcgtcta caccatgttc ggttaaactc aaaatacgtt
     3541 ttagatcttg caccgtgggc gaatcaacac taaaattttt ctccttgaac tcaatcccat
     3601 gtgcttccaa ccattgccgt gcaactctag aagaatgaca gcttgattgt gtatataacc
     3661 taatcattcc taatctgccc ctctctcgtt aaaattcatc acagcgtatt gatcgacatt
     3721 aacttctgcc tgtcacaaca tcctttaaac taaacgcatt cgttactgtc atgaccaatc
     3781 caataccccg tgaacacatc tttattatag gctctgaaca agggacatac cgaccgtttt
     3841 aagacgaata atctgaggat aatcgtttta agtacacttt taaacggttt aggaaagaac
     3901 gaacccagta cacgtaatgc taacaaatat cactgcaatt tctaatcgaa taacgctgaa
     3961 ttttcatcgc gtagcacata aaaagtcgcc tactaattta acaggcgact tccttggaac
     4021 tattatgact ttttagcaag ccatttagct agataacgat tagcttgtgc agaacaaagc
     4081 actttttcac catttgtcat ggttaatcgt cgcaagtgct tgtccaatga cttaatgcgt
     4141 ttcaagttaa caacatatga cttatgacac ctatagaaat taggactcaa atcaggaacg
     4201 tcctttaaca gtccatagta ttctaattca ccatcatcca aatggactac gattttatgg
     4261 ggactggttg aactttcaaa aaatataatg cttttaacat taattgatct gaccgtctca
     4321 ccaattttta tttgaacata gtcgtcttgg tcattttcat cggtttgaaa acgatcttgc
     4381 gccacgtgta aaaccttgct aaatcgctca tacaaggaat ctggaaaatc cttaagaata
     4441 aaatctaatg cctcaacttg atattgaaac accatcaaag ataactccgt gtgtgtcgtg
     4501 ataaaaataa tcttgctgcg acggcccatg tcacgaatct ggctagctag ttgaatacca
     4561 ttaatatctg aattaagggc aatatctaac acatagattg ccttttgagg ctgctgtgca
     4621 ttaaccttgt ctaacaattc gtggggatct tggcatgcta aacagatact catgtctagc
     4681 tgttgatcga cgattacctt agtaatgatt tgccgtattt gttgtaattg tttcggatca
     4741 tcttcgcaaa tgtagacact aatcattctg agatactcgc ttcaccgtca agcgttgtaa
     4801 gaataccgct cctaagactc tggtttcgag tatcatgttc tcattgcgat taacaatctt
     4861 acttaaacta ttcaatccaa tcccccgatt cttgccctta gtggaataac ctgcctcttt
     4921 cagcttccat aagggtggta actgttcaaa aacattgttt tgaatcaaga acaccgtact
     4981 atttttttcg ataaaaatgg cactcataat ctctccatca gcatgtccta ccgatgcttc
     5041 gattgcatta tccaacataa tccctaatgc aatgtctaaa tccaattcat taacagtaat
     5101 gtcaattaat ggttccttta aatcaaaatg aacttcaatc tcttgcgatt gtgcatagct
     5161 caacttacta aataggatac tcttaatcga cttcactttg acccgactca aatcttcaag
     5221 attatatttt tcttttaaca cccgatttga aaccggtgca agattctttt gataatattc
     5281 ttgtaaacct tctaaatcat cagttttcaa atattcatct atcgaaatca acatattctg
     5341 atagtcatgt ctgaaacgtc gcaactcatt atagtgagct tcgatttcat tcatatagcg
     5401 agtatcattt tgtatttgta ttctttgctt ttggacttca tatttggctc ttacattttt
     5461 taaatattcg ttataaatca ccaatactaa ccccattaca actgacaata taattaaatt
     5521 acttaatata acctggaact gattttccag accttcactc aacataatat acaagtatat
     5581 tatcattaat aatagtgcgg ttatgcgatt taagctctga ttactaaacg tgggactgaa
     5641 attcgtgcga tccattacaa tattaagaaa aattaagctt acgacactca atatgacaaa
     5701 cactaccaca tacccattag gaactttcat taaacgagtt aatatatcac aaatatggtc
     5761 aaccataatc gaccatatga acacttgaaa tgttatacat agtgcaccgc ttagaactcg
     5821 tacataccac caagtgaaaa atataaacat cattaacatt aaaaaagaaa aactaattcc
     5881 taactttgct aaaaaaatat aactcatcag catacagacg gataagaata taacatcaaa
     5941 aagtctcaca aaaaatatat ttctcaacaa agatttaatt atcaaataga tagataattc
     6001 ttggaagaca atcattaaca tatatctaca ctaatccttg ctttttaatt catcaggaat
     6061 tttagtttcg aataatatcc catggcagca cataaccaac tgtttagtac ctacgtattg
     6121 aaaaagatgg ctaagtactt tatacatttt ttctttcata attttccctc ctttcatagg
     6181 gcattagtaa taaagcggct aatgccatcg caattaaaat gattgtgcca aaataattat
     6241 tactaactat ttgtaacaaa ctcaaaatta atgacaatcc aattgcccgt cgctttaatt
     6301 tttttctcaa tgacttcgat gtaataggat tctttaccgt atcagctgga gcaaaaatac
     6361 ttatgattat tacaaatatt aaacttaata acaatctgta tacttcagaa ataccagttt
     6421 caatcacata cggcacaccc acaaacacaa agatagttaa tatcgtacat aacaaatccg
     6481 atttcaagtg acgtccatag gcaaagccac gcaaaactaa aaaactaccc ataaaaacta
     6541 acactgggac caactcgtgt agcagcaacg ctaagataat agtaattatc agcttaggaa
     6601 taacatttaa tacagtatca atgcctagtt taactagtaa tgcctgccgt ctttctagtt
     6661 gaagattctt ttgaatcgca gcgaataacc gatcgcttaa tttataaagc aatagttttt
     6721 gttctggctt ttccatatcc cactcctata atgctcaaat acatacctgt atcaacagtt
     6781 taaaacagta ttaattaatt gaaaagaata cataaatata ttaattattc aatattgttt
     6841 taagactaga aataaacatt taaagataca tcagtttaat tattcatacg aaactaaagt
     6901 ttcatgtaaa aagatcgtta atataaatca gtttcatcga tactccccct taatttttcc
     6961 ttagattaca agtcaaacta gacttaattt cactaattca cattactcaa tagattaata
     7021 tcaaatggtg aaaatcaacg aaaagaggag atctatcaag caatctcctc ttacataaag
     7081 ttatttatga acactgattt aagctaagct gccgatatca caatctcagc atccactaaa
     7141 tcagccttca agtttttgac atctaagtgg tcaaggtaga aatccgttac cttgtcacga
     7201 atttgttgtt caattactcg ccgtaatggc cgcgcaccca tcgcttcatc atagccttgt
     7261 tccatcagcc aatctttggc cgctttagtt acctcaagtt tgatggattt tttggctaac
     7321 gttttttgta catccgccaa catcaaatcg acaatttgac ttaagtcttg cttagtcaga
     7381 tgtgaaaatt ccacgattcc attaaaacgg ttcagaaatt ctgggcggaa aaatggtgct
     7441 aacttatcca ttaatgactg atctcgttgc ttgtcaccac ttaatgcttc attaccaaag
     7501 ccagcattag aagtagcgat aataatcgta tttttgaaat taatgacatt gccttgtcca
     7561 tccgttaagc gcccatcatc catcacttgt aacagtaacg ttaatacttg tggatcagcc
     7621 ttttcaattt catctaataa tacaatggaa tatggattac gccgaacccg ttcggttaga
     7681 gtattagcat tatcttcata gcctacgtat ccagccgagg taccaattaa tttcgacaca
     7741 gctgtacgat cagcatattc actcatatct agccgaataa tcgcattttt atttccaaac
     7801 atatctaagg ctaattgctt agctaattca gtctttccta cgccagttgg gcccacaaac
     7861 agaaaacttc caattggctg atcaccctct gaaaagcccg cacggttacg ccgaattgcc
     7921 ttcgctacca tttcaaccgc ttcatcttga ccgattacct tacttttcag acgcttatca
     7981 agatttttca agtgctcaat atcattagcg cccatatcag caactggtat accagttaaa
     8041 cgttcaaccg attgtgccac atcatcaatc gtggcagtga ttttttcttt ttgatccgtt
     8101 tttttaattt tttgcttggt ttcctcgatc gacttcttga tatcagcggc ttttgtaaag
     8161 tcctccgatt taacggcggc ctccttagtt gcctctaatt ttttaacgcg ttgatccaat
     8221 gtctcaacat cagtttgcga atttttagcc gctaaatgag ccgcagtcat gtcgatcaaa
     8281 tcgatagctt tatctggcaa agtgcgttgt ggtatatatt ggattgaata atccacagcc
     8341 gccttcaaaa catcatctgg taatacaaca tgatgatgct tttcgtacag ctttttaaca
     8401 ccttgtaata tacgtaaagt gtcagcggcc gtcggttcat taatcacaac atcattgaat
     8461 cgccgtgcca aagccgcatt tttcaaaata gtattgcgat attcatcttg agtcgtagcc
     8521 ccgattacag tcagctcgcc acgtgacaaa gcaggtttaa tgatatcagc caatcctttg
     8581 ccaccatctt caccaccagt ggcgcccgtg ccgataatct gatgaatttc atcgaagaat
     8641 agaataatat taccagctgc tttaacttcc tttactagct gtttaatatt ttcttcaaaa
     8701 gaaccgcgat attgagttcc tgcttccaaa gacgataaat caatcgaata gatttcttta
     8761 tcttgaatcg tttctggaac tttaccagcc acaattgctt gtgccagacc ttcgacgact
     8821 gcagttttac ctacaccagc atcaccaact aagattggat tatttttcgt cctacgactc
     8881 aaaatttctg cagtttcttg aatctcattc tcacgtccaa tcactggatc tagtaatcca
     8941 tcacgagcct gttccgtcaa attagtccct aacttttcta aaatcccccc ttttttaaca
     9001 gcctgtttac catctttaga tacttctatt gttttattat tttggggtag cttaccagtt
     9061 gctcggtatt gagcaaactc atccggtgtc agcgattgtc cattaactaa ataccgtgca
     9121 cgctccgaat tttgattatc catgcgccga aataattgat tgaaaacatc atccatatca
     9181 ttgttgaaaa aaggatcatt tccgtagaaa tttgccatat tacaacacct ccataaaaat
     9241 ttatatgtgt aacttagtga ccataatatc ctttaaaact acaactgaat cgtatcacga
     9301 tttttatgta tcgttaagta aagtgcttat agaatcaatt agaaataatt agaataattt
     9361 tgtttaaaca aaagagaaat caatttcata aaatgaattg atttccctac aaggttccct
     9421 atttaatagc ccttgataaa gaacttgaat taacaagtta ctttccagac caattttaat
     9481 ttaagagact gcgactcaaa aagcacaccc agtatcaagt taaggccaac tagttatcgt
     9541 taatattgcc acttaaatat caatactagc aatcatgata cacgtgtaaa atcataaacc
     9601 aaaacatatt acatgacgta acggcggtct tgggactgta aactcacagt aatgattcta
     9661 ttgagttgga taaggtgccg atgaccagta attgccataa atgcaattgc tttcggtaca
     9721 atcgtagtga catagccaac tgtctcggcc atctgcccat ttgttttata aaaccgtaat
     9781 gagactcgac atttttgatc atgcgcttgt tgtaatttac aataattatt ttcaacactc
     9841 aaattaaagt ctcccgttca aagaattcag gtttatttat tcgtcagtga atctatgtgt
     9901 ttgtttttct cattgttgac ggcgtaagtc cacattaagg agtcagctat tcagtaaaaa
     9961 ctaaataact agtattcatg ttcagctcag tataatatgc attgatggtt actaatcaaa
    10021 aatcgatctc taaatatcct aattactatg aaactttgaa gttaatttat gagaaaaata
    10081 actcacaaca aaactcatga ttacaacctt gtcatcataa ctagattatg aaacattcag
    10141 cctcctaaat aaaactggta tgcgcgcatg tgcgcatgtg tacagtatac tattgccagg
    10201 tatgtctgaa taaccgtttt aagacttgaa aaactcagct gggtgcttta ggacgctttt
    10261 tgtgcatttt aagacaatat cctaacttca acgccggcat agcttcaatt cgtcaatcag
    10321 tgtcttagtt cctcagctat ttctgttcag aacatcttcc tattacaata aaaagcgttg
    10381 atctcagcag aatttacttc caccaaaacc aacgctaaag tgttattata tcaggtattt
    10441 taaattcatt tcagacatta tattcagcat tacttctact acctaagtaa tttagcacgt
    10501 ttaacatctt caatcgtctt agttcccgct agttgcatat cgatcaacag ctcatcatta
    10561 aggtgactca ctacggaagc gacaccctgc gcaccaccca atgctaatcc atagataatc
    10621 ggccgagcaa gtgccaccag atctgcacca ttggctaacg ccttaaagac atgggagcca
    10681 cgccgaacac cgctatcaaa aattgttggg acgcgcccat taacggcttg cgcaatctcg
    10741 tgtaaaacat caaaggaagc tggaccacca tttaattgcc gaccgccatg gtttgaaaca
    10801 tagatacctt gagcaccagc cccgattgct aacaaggcat cttctggtta ctgaatcccc
    10861 ttcacaataa ctggtaaatt cgtatattct gtaatacgcc gaacatcagc tgggctaatc
    10921 ttttgcgccg cagcagcata gatttctatg atacctttcc ctttaccatc cccttcgctg
    10981 aacttagtca agttagccat tgggattgga aactggaaat tgttgataat atcagcttca
    11041 cgatacccgt caactgttgc atcaacagtc aaaatgattg ccttagcacc agccttcact
    11101 gcttcatcca ataaactctg attgaaattc caatccttgc tcatatataa ttggaaaaat
    11161 tggggcgcac ctttaccagc tgcggcagta tccgcaattg acgttgaaga ataagtactc
    11221 tgagccatga gtgccccaac ttgagccatc ccttcagcag tcgcagcttc accccgtgca
    11281 tgtgccaatc cttgagcggc cgctggagcc atcataatag gcgttttgag atctatgcca
    11341 aaagcctgag tctgtgtgct tggctgttcc atatccgtca atgctcgtgg cacaatttga
    11401 acatggttaa aggccattgt attctgcttt aaagtccatt cgtcttctga cccaccacta
    11461 atatagccaa agcctccgct cgggatgatc tttttagcag ctgcttccaa tgatggtaaa
    11521 tttaaaatcg ttaacttttg ctcacgatca ctctgttcat atccattaat aactgtcatt
    11581 atactaatct cctttacata accctttata attcatttaa taattggcta agtgccggtt
    11641 gatccgcttc agcgatacca tatcgttcac gatacttagc aatcgtatct gcatcaaagt
    11701 tttctggatc tactggaaca aaactagtat caattggatc aacattttta atttttgcat
    11761 caatcacaat tggtagttga ttaccattct gctgtagttg agtaactttc tgaaacgttg
    11821 ctttcaactc tttaaggtta gtcactttaa aaccaatcgc acccatgttg tctgccatct
    11881 tggcccaatc agcaccaatc aagtcaatcc catacggcgc ctgattagcg agtaactttt
    11941 catgttgaat aaagcctaat actttgtttt ctaaaaccac gttaatgact ggcaaatgat
    12001 atttaacttc cgttagtaag tctggcatca ccatggcata accaccatca ccagaaatac
    12061 tccaaacctg cttcttagga taattcaatt gggcggccaa acctgctggc aaaccaaaac
    12121 ccatcgtgcc ataccaagcc gacatcgtaa aagtctgttg cttattcaat ggtaactgtc
    12181 ggattgccca ttccgtatta ttcccaacat ccagaccaaa gacggcatca tcagtagcat
    12241 tgtctttaat agcttctagc accccttcag ccgtcaaccc tccttgatca tcagtagcaa
    12301 ttgtcttgag ccaccggttc cagttttgct tatcacgttg agcagctttc aagaacttag
    12361 ttggcttaat tgtcacttcg gattgaagta atgcttggaa aaattctttt gcatctgcaa
    12421 gaacagtaat atcagcatca tgttgtttgc ctaaatctgc taaattatta ttgacttgaa
    12481 taaacttaat tccttgtggc aagtaacgtg caaatggaaa gttagtacca acaaacaaaa
    12541 ctagatctgc cgcttgcgag acttcaaagg cgggtttagt tcctagtcga ccgcgagagc
    12601 ccatgaaatt aggatggtca gttggcataa taccagttgc tggagccgtc gacaaaaccg
    12661 gcaaactaaa tttttcagaa actgcgataa cttcttgacg cgcattatag gcacccttgc
    12721 caatccataa aacagggtgt tgagcagctt tcaaagccgc tatcgtctgc tgaacgtcat
    12781 ctaatttcgg cattaagacc tgttgactgc cgctaagtga agccgtttta aaaccatcaa
    12841 actcaatatc ttgaccagac aaatcatctg gaataataac aacagaaacc gaacgggtcg
    12901 cgtatgctga tctaattgct tcatcaacca cgtatggaat ctgttcagcc gttgtcactt
    12961 gtttatgaaa ttcggctaca tctgcaaaaa ttggatcttg gttcatttct tgaaagaagt
    13021 tcgtattcat aatggatgtt gctgattgac cgactaaagc tagcaccggt acgtgatcca
    13081 tcttggcatc gtataatccg ttcaagagat gaacggcgcc cggtcctgct gaaccaaagc
    13141 taacaccaat cgtcccagtt aatttagcat ctgccgcggc agctaaagca ccaacttctt
    13201 catgacgtac ttgaatatac ttcaagtggt ctttctcttg gtagaaccca tctaccgtgt
    13261 tattaatcga gtcagctgta ataccataga tatgatcaat gttccagtcg actaacactt
    13321 gtgccaatgc ttgtcctgct ttaattttag tcatttccat taccctcttt ttgttgttac
    13381 ttttttgagc acaactatat cctaaataaa aacttgaccc ttgtcaagtc tttatcttaa
    13441 attatgcttg ttgttgaaca gcgctaatgt catcaataat atcttgcagc gtcactcgcg
    13501 acatacgtgc ctcagcacta ttctgaatat cacaatagta tttttccatc actcgcggaa
    13561 ttaccgaccc gaccggacac gtctccgaag tattatgatc aacgtttaaa aaattacgct
    13621 tagccaccac tgctacatag atatctttca aggtaatatc attgggcgaa caagctaatg
    13681 ttggtctagc aacgccacga accgaagtta acaagcctgc ttttcttaac ttactcatca
    13741 ttcttctgac catggtagga tccgtattta aactactagc aatatgctca cttttcagct
    13801 ggtcatcagt atgcaacgca atatatgcca taatatgcgt cgcatcactt aattgtgtat
    13861 tagccatcta gacacctccc atatccatct ctattgttac ttattttagc acatctaaca
    13921 tgaacataaa agcgattaag gaaataagtt aggcttcttt ccctaatcgc aacataagat
    13981 tatttgataa tctccattaa ttcaatcaaa cttattcaag acatcgatag tagctgaatt
    14041 taaaacccac cctgtccaat ttgatgttgc aaatcatcta agccaaattg ttttaaataa
    14101 gttgaaagtg gttgtaaatc ttgagcttca taccgttgtt taaatgcttc aatatcagct
    14161 gccgaactcg ttgccgaatc taaacgaagc ttttcagcag gcagtggccg atctcctgta
    14221 atcaccgcat caatcagaac tggttcatgc tgagcgattg ctttggcttg ttcaaaaaca
    14281 tcaggtaatt gctcaatctt attaactcga aaagcttgca tgtgcacgcc atcggcaatc
    14341 ttactaaaat caatatcatt gaattcaacg ccaataaaat cattctgatt agtatcttcc
    14401 tgctcatctt tgataaatcc atattggcag ttggtgaaaa caacattaat cactggtaaa
    14461 tggtattgaa cttgcgtcgc caaatcttgc atggtcatcg aagcgccacc atcaccggcc
    14521 agattaaaca cctgccgctc aggataatta agtttggcag caattgctcc cggaatacca
    14581 actcccatcg tagcaaataa gttagaagta atgtgccgat tggacggcgt taatttcaaa
    14641 tgtcgattcg cattcaaatt gatatcacca acatcaatcg aatagattgc atcaggctcc
    14701 gcaattttat taaccgcacg tagcacttga tatgcttgta aaggcccttc ctgcttatct
    14761 tctaatgaag ctagataagc ccgccaattt ttaacattgg ctaaattggc ttgccaccaa
    14821 ggtgtcgact cccgttcaga tacctgtgct aaaattgcag ccagcgtttt ttgtgcatca
    14881 gcaagtaccg caatatctgt tttatgtcgt ttacctaact tagctggatc aatatcaatt
    14941 tgtaagaaat aacgcgtatt tttaaacgct ttggaaactt ctgcaaacgg ataattatta
    15001 ccaacaaata aaacaacgtc ggcttgcgca agtgcctcat tcgccggttt ttgtgccacc
    15061 cgattagcag aacccaaata ggctggataa cgatccgcga caataccctt agctggatac
    15121 gtactcatta atggaatttt caacgtttta ctcaattgtt cgagttcttt accagcctta
    15181 cgagctccaa tgccatagta aataagtggc cgttcagctg cgagtaaagt ctgtgtcaat
    15241 ctcgtcactg cttgaacgtc gggttctggt aataacggcg tttgataact attagcggaa
    15301 gcataccaat cttcagctgg aatctgttgc catggtaaat cgactggaat ttgcacaacc
    15361 gcaacacctt ggtgcgcgta ggcgcgtcga attgcttcgt caataacatg tggcaacgtg
    15421 gcagcattga cggctgttac attataatct gcaacgtccg cataaatcgg attctcattc
    15481 atttcttgga acgtatccat gttcatccca gtagttccaa attgaccaat aagtgctaga
    15541 acagggacat ggtcttcacg cgcatcatat aacccattca taagatgagt gccaccaggt
    15601 cccgctgagc cgaagcaaac cccgatttta cccgttagct tagcatcagc agcggcggcc
    15661 attgcaccaa cttcttcatg ccgtacttga atataatgga ttcgatccct ttctgctgat
    15721 aatgcgtcca taattgaatt aattgaacct ccaggaatac catacaaatg atctactccc
    15781 caagcttcta aaactttaat aactgctgca cctgctagta tgttagtttg ttttgtttgt
    15841 ttcataacca taataaagcc cccatttcat gcacaattta attacgcaca atttaataaa
    15901 cgaatattac catagcaaac gcttacattc aagtggtcat aaactcatgc tttttaccac
    15961 ttaatcacga ttcaaacgca ttgtagatca acaacagcgc tagtctgctt gccttgatga
    16021 accaccatcg ctgttgacag ttagtatctc atacattcat tttttaaaca attttagtaa
    16081 ttagtgtatg ttttacaggg gcatacttcc aacaatgtct gcatgtttag aagctagcca
    16141 ttcttcgaaa actaactacc gctttcaaaa catgacctta actcaactcg acacagagca
    16201 aaataacatc tgccaagtta attattcagc tataatccgt accacgctac caactttaaa
    16261 atcaggataa tcgccctgct caacatataa cgtcccaggc aatttagcct cctttgcacc
    16321 cgtaaaacta atagccgtat ggcctaatct tccaaggtta gtctggactt caccaccaac
    16381 tgctgtaatt tgatagactt gattgtcgac ttcaagtttc attcctgctg tgatttgctc
    16441 acttattggg acaacttcga taataaagca agaaggccgt aatgcgtctg gagcttcatc
    16501 accaaataat actgccatgc caatcgattt aaaatcagca gattccgcac ctatttctaa
    16561 gacctttgtt gaaaagataa ttctctcttt tgtcatcata caatacacct caaaccttct
    16621 aaaaatttat tttgaatata atccaaaact tgcaatccaa gcaataaaga cccgcggaac
    16681 gccgttgata aaccgactat ataacactga tggcacccca acttcaaccg tcttag
//
