LOCUS       gnlProkkaGPDPALNF_33   16746 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GPDPALNF_33.
ACCESSION   gnlProkkaGPDPALNF_33
VERSION     gnlProkkaGPDPALNF_33
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 07:27:17
            Original ID  :: gnl|Prokka|GPDPALNF_33
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16746
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..87
                     /locus_tag="ctg33_1"
                     /transl_table=11
                     /translation="MFSHSKTPEIVVQSRGFTSAIEKLDLFV"
     protocluster    1..16746
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[6040:6746]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6041..6746
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..16746
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16746
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(143..487)
                     /locus_tag="ctg33_2"
                     /transl_table=11
                     /translation="MISDILSFTIFGSGAFQIAFLLTAFLGGFIDGLFLYRKSVNWLSV
                     VMTQILVMIFVSLMMDSWLISVLFGTNFKVLLLGRLARVIIQIPLQVIAIFYFIKALEK
                     RHVFDRMRLR"
     CDS             complement(886..1020)
                     /locus_tag="ctg33_3"
                     /transl_table=11
                     /translation="MIKSILKFCLAATLIVSGVLIGGTVLTAKGIDNLGDKLQDKLHG"
     CDS             complement(1037..1282)
                     /locus_tag="ctg33_4"
                     /transl_table=11
                     /translation="MHWLWVLIIGAIIGAIAGAITNKGKSMGWISNIIAGLVGSAIGEA
                     LLGSWGPQLAGMAIVPSIIGGVIVVAITSFVLTRMD"
     CDS             1568..3082
                     /locus_tag="ctg33_5"
                     /transl_table=11
                     /translation="MLAFKLCKSFLVIYVKRAIKMTEKLTTETGQPWANNEHSQTAGAR
                     GPVLMQDYNLLEKLAHFDRERIPERVVHAKGAGAKGFFELENDMGEYTKADLFNGVGKK
                     TPVILRFSQVAGEKGYPDTVRDVRGFALKFYTQQGNYDLVGNNTPVFFVNDPLKFPDFI
                     HSQKRDPKTNRRTQNMQWDFWAHSPESLHQVTYLMGDRGLPASYRTMNGYGSHTFKWVN
                     QNGEQFWVKYHFISDQGVKNMTAQAAEKAMSQDLDYLQDDLYDAIQEKNYPSWTMYVQI
                     LPYEEGLNYKWDIFDVTKVISHKDYPLIKVGKLTLNENPTNNFTDIEEAAMSPANFVPG
                     IEPSPDKLLQGRLFSYKDAQRYRLGANFEDLPVNKPVVPVHNYERDGYMKINNQGAEVN
                     YEPNALHGPEEVPDAALSPDSVRGETRAQPYRYQVDYTTQAGDLYRLMSEPEQERLINT
                     IKDALGQVTLPGVKKLEIKQFYEADKNYGTRVANALGMNIADIISD"
     CDS             complement(3240..3677)
                     /locus_tag="ctg33_6"
                     /transl_table=11
                     /translation="MIRLYTQSSCHSSRVARQWLEAHGIEFKEKNFSVDSPTVQDLKRI
                     LSLTEHGVDDIISARSKDYPEIAPKLPEMPLNEALKLLCDHPKLLRRPIIISDSKIQVG
                     FNEDDIRQFIPRPVRRLKFNALLSRLDGNTGDHIINKRMVE"
     CDS             complement(4033..4776)
                     /locus_tag="ctg33_7"
                     /transl_table=11
                     /translation="MISVYICEDDPKQLQQIRQIITKVIVDQQLDMSICLACQDPHELL
                     DKVNAQQPQKAIYVLDIALNSDINGIQLASQIRDMGRRSKIIFITTHTELSLMVFQYQV
                     EALDFILKDFPDSLYERFSKVLHVAQDRFQTDENDQDDYVQIKIGETVRSINVKSIIFF
                     ESSTSPHKIVVHLDDGELEYYGLLKDVPDLSPNFYRCHKSYVVNLKRIKSLDKHLRRLT
                     MTNGEKVLCSAQANRYLAKWLAKKS"
     CDS             complement(4769..6031)
                     /locus_tag="ctg33_8"
                     /transl_table=11
                     /translation="MLMIVFQELSIYLIIKSLLRNIFFVRLFDVIFLSVCMLMSYIFLA
                     KLGISFSFLMLMMFIFFTWWYVRVLSGALCITFQVFIWSIMVDHICDILTRLMKVPNGY
                     VVVFVILSVVSLIFLNIVMDRTNFSPTFSNQSLNRITALLLMIIYLYIMLSEGLENQFQ
                     VILSNLIILSVVMGLVLVIYNEYLKNVRAKYEVQKQRIQIQNDTRYMNEIEAHYNELRR
                     FRHDYQNMLISIDEYLKTDDLEGLQEYYQKNLAPVSNRVLKEKYNLEDLSRVKVKSIKS
                     ILFSKLSYAQSQEIEVHFDLKEPLIDITVNELDLDIALGIMLDNAIEASVGHADGEIMS
                     AIFIEKNSTVFLIQNNVFEQLPPLWKLKEAGYSTKGKNRGIGLNSLSKIVNRNENMILE
                     TRVLGAVFLQRLTVKRVSQND"
     CDS             complement(6041..6169)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_9"
                     /sec_met_domain="TIGR04223 (E-value: 2e-08, bitscore: 25.3,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEKMYKVLSHLFQYVGTKQLVMCCHGILFETKIPDELKSKD"
     CDS             complement(6150..6746)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_10"
                     /sec_met_domain="AgrB (E-value: 1.6e-35, bitscore: 113.1,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKPEQKLLLYKLSDRLFAAIQKNLQLERRQALLVKLGIDTVLNV
                     IPKLIITIILALLLHELVPVLVFMGSFLVLRGFAYGRHLKSDLLCTILTIFVFVGVPYV
                     IETGISEVYRLLLSLIFVIIISIFAPADTVKNPITSKSLRKKLKRRAIGLSLILSLLQI
                     VSNNYFGTIILIAMALAALLLMPYERRENYERKNV"
     CDS             complement(7114..9228)
                     /gene_functions="other (smcogs) SMCOG1223:ATPase (Score:
                     962; E-value: 4.5e-291)"
                     /gene_kind="other"
                     /locus_tag="ctg33_11"
                     /transl_table=11
                     /translation="MANFYGNDPFFNNDMDDVFNQLFRRMDNQNSERARYLVNGQSLTP
                     DEFAQYRATGKLPQNNKTIEVSKDGKQAVKKGGILEKLGTNLTEQARDGLLDPVIGREN
                     EIQETAEILSRRTKNNPILVGDAGVGKTAVVEGLAQAIVAGKVPETIQDKEIYSIDLSS
                     LEAGTQYRGSFEENIKQLVKEVKAAGNIILFFDEIHQIIGTGATGGEDGGKGLADIIKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNDVVINEPTAADTLRILQGVKKLYEKH
                     HHVVLPDDVLKAAVDYSIQYIPQRTLPDKAIDLIDMTAAHLAAKNSQTDVETLDQRVKK
                     LEATKEAAVKSEDFTKAADIKKSIEETKQKIKKTDQKEKITATIDDVAQSVERLTGIPV
                     ADMGANDIEHLKNLDKRLKSKVIGQDEAVEMVAKAIRRNRAGFSEGDQPIGSFLFVGPT
                     GVGKTELAKQLALDMFGNKNAIIRLDMSEYADRTAVSKLIGTSAGYVGYEDNANTLTER
                     VRRNPYSIVLLDEIEKADPQVLTLLLQVMDDGRLTDGQGNVINFKNTIIIATSNAGFGN
                     EALSGDKQRDQSLMDKLAPFFRPEFLNRFNGIVEFSHLTKQDLSQIVDLMLADVQKTLA
                     KKSIKLEVTKAAKDWLMEQGYDEAMGARPLRRVIEQQIRDKVTDFYLDHLDVKNLKADL
                     VDAEIVISAA"
     CDS             complement(9619..9852)
                     /locus_tag="ctg33_12"
                     /transl_table=11
                     /translation="MSVENNYCKLQQAHDQKCRVSLRFYKTNGQMAETVGYVTTIVPKA
                     IAFMAITGHRHLIQLNRIITVSLQSQDRRYVM"
     CDS             complement(10489..10845)
                     /locus_tag="ctg33_13"
                     /transl_table=11
                     /translation="MLAIGAGAQGIYVSNHGGRQLNGGPASFDVLHEIAQAVNGRVPTI
                     FDSGVRRGSHVFKALANGADLVALARPIIYGLALGGAQGVASVVSHLNDELLIDMQLAG
                     TKTIEDVKRAKLLR"
     CDS             complement(10858..11589)
                     /locus_tag="ctg33_14"
                     /transl_table=11
                     /translation="MTVINGYEQSDREQKLTILNLPSLEAAAKKIIPSGGFGYISGGSE
                     DEWTLKQNTMAFNHVQIVPRALTDMEQPSTQTQAFGIDLKTPIMMAPAAAQGLAHARGE
                     AATAEGMAQVGALMAQSTYSSTSIADTAAAGKGAPQFFQLYMSKDWNFNQSLLDEAVKA
                     GAKAIILTVDATVDGYREADIINNFQFPIPMANLTKFSEGDGKGKGIIEIYAAAAQKIS
                     PADVRRITEYTNLPVIVKGIQ"
     CDS             complement(11616..13370)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 471.4;
                     E-value: 6.8e-143)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_15"
                     /sec_met_domain="TPP_enzyme_N (E-value: 2e-41, bitscore:
                     132.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3e-32, bitscore:
                     102.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEMTKIKAGQALAQVLVDWNIDHIYGITADSINNTVDGFYQEKDH
                     LKYIQVRHEEVGALAAAADAKLTGTIGVSFGSAGPGAVHLLNGLYDAKMDHVPVLALVG
                     QSATSIMNTNFFQEMNQDPIFADVAEFHKQVTTAEQIPYVVDEAIRSAYATRSVSVVII
                     PDDLSGQDIEFDGFKTASLSGSQQVLMPKLDDVQQTIAALKAAQHPVLWIGKGAYNARQ
                     EVIAVSEKFSLPVLSTAPATGIMPTDHPNFMGSRGRLGTKPAFEVSQAADLVLFVGTNF
                     PFARYLPQGIKFIQVNNNLADLGKQHDADITVLADAKEFFQALLQSEVTIKPTKFLKAA
                     QRDKQNWNRWLKTIATDDQGGLTAEGVLEAIKDNATDDAVFGLDVGNNTEWAIRQLPLN
                     KQQTFTMSAWYGTMGFGLPAGLAAQLNYPKKQVWSISGDGGYAMVMPDLLTEVKYHLPV
                     INVVLENKVLGFIQHEKLLANQAPYGIDLIGADWAKMADNMGAIGFKVTNLKELKATFQ
                     KVTQLQQNGNQLPIVIDAKIKNVDPIDTSFVPVDPENFDADTIAKYRERYGIAEADQPA
                     LSQLLNEL"
     CDS             complement(13452..13877)
                     /locus_tag="ctg33_16"
                     /transl_table=11
                     /translation="MANTQLSDATHIMAYIALHTDDQLKSEHIASSLNTDPTMVRRMMS
                     KLRKAGLLTSVRGVARPTLACSPNDITLKDIYVAVVAKRNFLNVDHNTSETCPVGSVIP
                     RVMEKYYCDIQNSAEARMSRVTLQDIIDDISAVQQQA"
     CDS             complement(14050..15861)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 494.2;
                     E-value: 8.6e-150)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_17"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.3e-44, bitscore:
                     142.8, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-38, bitscore:
                     123.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVMKQTKQTNILAGAAVIKVLEAWGVDHLYGIPGGSINSIMDALS
                     AERDRIHYIQVRHEEVGAMAAAADAKLTGKIGVCFGSAGPGGTHLMNGLYDAREDHVPV
                     LALIGQFGTTGMNMDTFQEMNENPIYADVADYNVTAVNAATLPHVIDEAIRRAYAHQGV
                     AVVQIPVDLPWQQIPAEDWYASANSYQTPLLPEPDVQAVTRLTQTLLAAERPLIYYGIG
                     ARKAGKELEQLSKTLKIPLMSTYPAKGIVADRYPAYLGSANRVAQKPANEALAQADVVL
                     FVGNNYPFAEVSKAFKNTRYFLQIDIDPAKLGKRHKTDIAVLADAQKTLAAILAQVSER
                     ESTPWWQANLANVKNWRAYLASLEDKQEGPLQAYQVLRAVNKIAEPDAIYSIDVGDINL
                     NANRHLKLTPSNRHITSNLFATMGVGIPGAIAAKLNYPERQVFNLAGDGGASMTMQDLA
                     TQVQYHLPVINVVFTNCQYGFIKDEQEDTNQNDFIGVEFNDIDFSKIADGVHMQAFRVN
                     KIEQLPDVFEQAKAIAQHEPVLIDAVITGDRPLPAEKLRLDSATSSAADIEAFKQRYEA
                     QDLQPLSTYLKQFGLDDLQHQIGQGGF"
     CDS             complement(16232..16618)
                     /locus_tag="ctg33_18"
                     /transl_table=11
                     /translation="MYCMMTKERIIFSTKVLEIGAESADFKSIGMAVLFGDEAPDALRP
                     SCFIIEVVPISEQITAGMKLEVDNQVYQITAVGGEVQTNLGRLGHTAISFTGAKEAKLP
                     GTLYVEQGDYPDFKVGSVVRIIAE"
ORIGIN
        1 aaatttagtc atagtaaaac ccccgagatt gttgtccaat ctcgggggtt cacttcagca
       61 atagaaaagt tagacttatt tgtttaacga ttgtagcgcg tttcataccg tgttcaacct
      121 ctttttgtag catccatcga tattatctaa gcctcattct atcaaaaacg tgtcgttttt
      181 ctaacgcctt aatgaagtaa aaaatagcaa tcacctgtaa tggtatctga atgatgacgc
      241 gtgccaatct tcccaacaat aacactttaa aattagtgcc aaatagcact gaaattagcc
      301 atgagtccat catcaaacta acaaaaatca ttacaagtat ttgcgtcatc acaacggata
      361 accaattgac tgatttacga tataaaaaca aaccgtcaat aaatccccct aaaaatgcag
      421 ttaacaaaaa ggcaatctga aacgcgccgg aaccaaaaat agtaaagctt aatatatcgg
      481 agatcatctc caagagacca ccccaaatgg gaccatatag ataaccaata caagccatag
      541 acaaaaagcc aaaagataat tgaaaatacg ctggtccgat agcaattttg tataaaataa
      601 cgtctaaggc caataagaaa gccgatgtag tcagcactaa taaattcatt tttggcaact
      661 gaaaaacatt tttcgcaata agtttagaca taggccaatc ctcttttttt gattttaatc
      721 ataccctcat tcttaataaa agtaaatatt acttttattc gattgaaggt agtttaaaat
      781 cgtcgctctt gatttagttc cttgaactca atgatattac tcatactaaa agccactaac
      841 aggtcaacta gtacacccat cagtggctca ttgtaaaatt aatttttatc catgtaactt
      901 atcttgtaat ttatcaccca agttatcaat tcccttagca gtaagtacgg tcccaccaat
      961 aagaacacca cttacgatta aggttgcagc taaacaaaac tttaaaatgc ttttaatcat
     1021 cgcaatcatc tccttactaa tccatccgtg tcagaacaaa tgaggttatc gcaacaacaa
     1081 tcacaccacc aataattgaa ggaacaattg ccattccggc taattgtggt ccccatgatc
     1141 ccaaaagagc ttccccaatt gcagatccaa ccaatccggc aataatatta ctaatccacc
     1201 ccatcgattt acctttatta gtaatagcac ctgcaattgc accaataata gcaccaatga
     1261 tcaaaaccca taaccaatgc ataaaatccc tcctagactt attaaaccgc ttaaatacaa
     1321 taatagaatt acacgaatat ttaagccgat tcataaatga ttacttctta taattatcat
     1381 tttacaatta tcgataatga tagacaaata taacacatta tttaataaat gggtcgctac
     1441 tatttctcat gtgacgattc cgggtggcct agaaaatatc aaacagcttg atagctgatt
     1501 aaaattaaac tacgccacat gaacgattaa cttaactgtg cataatgatt gaagtcactc
     1561 tgttaaggtg ttagcgttta aattgtgcaa gagctttctt gtaatttacg tgaaaagggc
     1621 gattaaaatg acggaaaaat taacgacgga aaccggccaa ccatgggcta acaatgaaca
     1681 ttcccaaacg gcaggagctc gtggtcccgt attaatgcaa gactataatc ttttggaaaa
     1741 actagcccat tttgatcgtg aacgaattcc agaacgggtc gttcatgcta agggggccgg
     1801 agcaaaaggt ttttttgaac ttgaaaacga catgggggaa tatactaagg cagacttatt
     1861 taatggtgtc ggtaagaaaa ctcccgtaat cttaaggttc tcacaagttg ccggtgaaaa
     1921 aggttatcct gacaccgttc gagacgtgcg cggttttgcc ttaaaatttt atactcagca
     1981 aggcaattat gatctcgttg gaaacaacac accggtcttt tttgtaaacg accctttaaa
     2041 atttcctgac ttcatccatt cacaaaaacg ggatcctaaa acgaaccgtc gtacgcaaaa
     2101 tatgcaatgg gatttttggg ctcattctcc agaatcattg caccaggtca cttatttaat
     2161 gggcgaccga ggtcttcctg cgtcctatcg aaccatgaat ggttacggtt cccatacttt
     2221 taaatgggtt aatcagaatg gcgaacagtt ttgggttaag tatcacttca tctcagacca
     2281 aggcgttaaa aatatgactg ctcaagcagc tgaaaaagca atgagccaag atttagatta
     2341 cttacaagat gacttatatg atgcaattca agaaaaaaat tacccatcat ggacgatgta
     2401 tgtccaaatc ttgccatatg aggaaggtct aaactataaa tgggacattt ttgatgtcac
     2461 taaagtcatc tcccacaaag actatccact aattaaagtc ggcaaactaa ctttaaatga
     2521 gaatcccact aataacttta ccgatattga agaggcggcc atgtcgccag caaattttgt
     2581 tcctggtatc gaaccatctc ccgacaaatt actacaaggt cgcctattct cctataaaga
     2641 tgcacagcga tatcggttag gtgccaactt tgaagattta cccgtgaaca agccggttgt
     2701 tccagttcat aattatgaac gtgatggtta catgaaaatt aataatcaag gtgctgaggt
     2761 caactacgag cctaatgcac tgcatgggcc agaagaggtg ccggatgccg cactttcacc
     2821 tgattctgtt cgtggtgaaa cacgcgcaca gccttatcgc tatcaagttg attacacaac
     2881 tcaagcaggc gacctatatc gcttaatgtc agaacccgag caagaacgct taattaatac
     2941 tatcaaagat gcgttaggcc aagttacttt gcctggtgtc aaaaaactcg aaatcaagca
     3001 attttatgag gccgacaaaa actacggtac acgcgtggct aatgctctgg gaatgaatat
     3061 tgctgatatt atcagtgatt aatattttga ccggatgtta tccagcgcga tattattttt
     3121 gttataaaga atgatgatgc cgtctcatgg ttattaacta aagagcgaca ggttagactc
     3181 atatcgtgta agtctagctt gtcgctcttt aattaacaaa aaatcttaga tatagcttac
     3241 tactcgacca tccttttatt aataatgtga tcccctgtat taccatctag acgactcaac
     3301 aatgcattga actttagtcg ccgaactggt cgtggaataa attggcgaat atcatcttca
     3361 ttaaagccaa cttgaatttt actatcacta atgatgatag gccgacgtaa caacttcgga
     3421 tgatcacaca acaatttaag tgcctcattc aatggcattt cgggtaactt aggcgcaatt
     3481 tcaggatagt ctttagatcg agctgagata atatcgtcta caccatgttc ggttaaactc
     3541 aaaatacgtt ttagatcttg caccgtgggc gaatcaacac taaaattttt ctccttgaac
     3601 tcaatcccat gtgcttccaa ccattgccgt gcaactctag aagaatgaca gcttgattgt
     3661 gtatataacc taatcattcc taatctgccc ctctctcgtt aaaattcatc acagcgtatt
     3721 gatcgacatt aacttctgcc tgtcacaaca tcctttaaac taaacgcatt cgttactgtc
     3781 atgaccaatc caataccccg tgaacacatc tttattatag gctctgaaca agggacatac
     3841 cgaccgtttt aagacgaata atctgaggat aatcgtttta agtacacttt taaacggttt
     3901 aggaaagaac gaacccagta cacgtaatgc taacaaatat cactgcaatt tctaatcgaa
     3961 taacgctgaa ttttcatcgc gtagcacata aaaagtcgcc tactaattta acaggcgact
     4021 tccttggaac tattatgact ttttagcaag ccatttagct agataacgat tagcttgtgc
     4081 agaacaaagc actttttcac catttgtcat ggttaatcgt cgcaagtgct tgtccaatga
     4141 cttaatgcgt ttcaagttaa caacatatga cttatgacac ctatagaaat taggactcaa
     4201 atcaggaacg tcctttaaca gtccatagta ttctaattca ccatcatcca aatggactac
     4261 gattttatgg ggactggttg aactttcaaa aaatataatg cttttaacat taattgatct
     4321 gaccgtctca ccaattttta tttgaacata gtcgtcttgg tcattttcat cggtttgaaa
     4381 acgatcttgc gccacgtgta aaaccttgct aaatcgctca tacaaggaat ctggaaaatc
     4441 cttaagaata aaatctaatg cctcaacttg atattgaaac accatcaaag ataactccgt
     4501 gtgtgtcgtg ataaaaataa tcttgctgcg acggcccatg tcacgaatct ggctagctag
     4561 ttgaatacca ttaatatctg aattaagggc aatatctaac acatagattg ccttttgagg
     4621 ctgctgtgca ttaaccttgt ctaacaattc gtggggatct tggcatgcta aacagatact
     4681 catgtctagc tgttgatcga cgattacctt agtaatgatt tgccgtattt gttgtaattg
     4741 tttcggatca tcttcgcaaa tgtagacact aatcattctg agatactcgc ttcaccgtca
     4801 agcgttgtaa gaataccgct cctaagactc tggtttcgag tatcatgttc tcattgcgat
     4861 taacaatctt acttaaacta ttcaatccaa tcccccgatt cttgccctta gtggaataac
     4921 ctgcctcttt cagcttccat aagggtggta actgttcaaa aacattgttt tgaatcaaga
     4981 acaccgtact atttttttcg ataaaaatgg cactcataat ctctccatca gcatgtccta
     5041 ccgatgcttc gattgcatta tccaacataa tccctaatgc aatgtctaaa tccaattcat
     5101 taacagtaat gtcaattaat ggttccttta aatcaaaatg aacttcaatc tcttgcgatt
     5161 gtgcatagct caacttacta aataggatac tcttaatcga cttcactttg acccgactca
     5221 aatcttcaag attatatttt tcttttaaca cccgatttga aaccggtgca agattctttt
     5281 gataatattc ttgtaaacct tctaaatcat cagttttcaa atattcatct atcgaaatca
     5341 acatattctg atagtcatgt ctgaaacgtc gcaactcatt atagtgagct tcgatttcat
     5401 tcatatagcg agtatcattt tgtatttgta ttctttgctt ttggacttca tatttggctc
     5461 ttacattttt taaatattcg ttataaatca ccaatactaa ccccattaca actgacaata
     5521 taattaaatt acttaatata acctggaact gattttccag accttcactc aacataatat
     5581 acaagtatat tatcattaat aatagtgcgg ttatgcgatt taagctctga ttactaaacg
     5641 tgggactgaa attcgtgcga tccattacaa tattaagaaa aattaagctt acgacactca
     5701 atatgacaaa cactaccaca tacccattag gaactttcat taaacgagtt aatatatcac
     5761 aaatatggtc aaccataatc gaccatatga acacttgaaa tgttatacat agtgcaccgc
     5821 ttagaactcg tacataccac caagtgaaaa atataaacat cattaacatt aaaaaagaaa
     5881 aactaattcc taactttgct aaaaaaatat aactcatcag catacagacg gataagaata
     5941 taacatcaaa aagtctcaca aaaaatatat ttctcaacaa agatttaatt atcaaataga
     6001 tagataattc ttggaagaca atcattaaca tatatctaca ctaatccttg ctttttaatt
     6061 catcaggaat tttagtttcg aataatatcc catggcagca cataaccaac tgtttagtac
     6121 ctacgtattg aaaaagatgg ctaagtactt tatacatttt ttctttcata attttccctc
     6181 ctttcatagg gcattagtaa taaagcggct aatgccatcg caattaaaat gattgtgcca
     6241 aaataattat tactaactat ttgtaacaaa ctcaaaatta atgacaatcc aattgcccgt
     6301 cgctttaatt tttttctcaa tgacttcgat gtaataggat tctttaccgt atcagctgga
     6361 gcaaaaatac ttatgattat tacaaatatt aaacttaata acaatctgta tacttcagaa
     6421 ataccagttt caatcacata cggcacaccc acaaacacaa agatagttaa tatcgtacat
     6481 aacaaatccg atttcaagtg acgtccatag gcaaagccac gcaaaactaa aaaactaccc
     6541 ataaaaacta acactgggac caactcgtgt agcagcaacg ctaagataat agtaattatc
     6601 agcttaggaa taacatttaa tacagtatca atgcctagtt taactagtaa tgcctgccgt
     6661 ctttctagtt gaagattctt ttgaatcgca gcgaataacc gatcgcttaa tttataaagc
     6721 aatagttttt gttctggctt ttccatatcc cactcctata atgctcaaat acatacctgt
     6781 atcaacagtt taaaacagta ttaattaatt gaaaagaata cataaatata ttaattattc
     6841 aatattgttt taagactaga aataaacatt taaagataca tcagtttaat tattcatacg
     6901 aaactaaagt ttcatgtaaa aagatcgtta atataaatca gtttcatcga tactccccct
     6961 taatttttcc ttagattaca agtcaaacta gacttaattt cactaattca cattactcaa
     7021 tagattaata tcaaatggtg aaaatcaacg aaaagaggag atctatcaag caatctcctc
     7081 ttacataaag ttatttatga acactgattt aagctaagct gccgatatca caatctcagc
     7141 atccactaaa tcagccttca agtttttgac atctaagtgg tcaaggtaga aatccgttac
     7201 cttgtcacga atttgttgtt caattactcg ccgtaatggc cgcgcaccca tcgcttcatc
     7261 atagccttgt tccatcagcc aatctttggc cgctttagtt acctcaagtt tgatggattt
     7321 tttggctaac gttttttgta catccgccaa catcaaatcg acaatttgac ttaagtcttg
     7381 cttagtcaga tgtgaaaatt ccacgattcc attaaaacgg ttcagaaatt ctgggcggaa
     7441 aaatggtgct aacttatcca ttaatgactg atctcgttgc ttgtcaccac ttaatgcttc
     7501 attaccaaag ccagcattag aagtagcgat aataatcgta tttttgaaat taatgacatt
     7561 gccttgtcca tccgttaagc gcccatcatc catcacttgt aacagtaacg ttaatacttg
     7621 tggatcagcc ttttcaattt catctaataa tacaatggaa tatggattac gccgaacccg
     7681 ttcggttaga gtattagcat tatcttcata gcctacgtat ccagccgagg taccaattaa
     7741 tttcgacaca gctgtacgat cagcatattc actcatatct agccgaataa tcgcattttt
     7801 atttccaaac atatctaagg ctaattgctt agctaattca gtctttccta cgccagttgg
     7861 gcccacaaac agaaaacttc caattggctg atcaccctct gaaaagcccg cacggttacg
     7921 ccgaattgcc ttcgctacca tttcaaccgc ttcatcttga ccgattacct tacttttcag
     7981 acgcttatca agatttttca agtgctcaat atcattagcg cccatatcag caactggtat
     8041 accagttaaa cgttcaaccg attgtgccac atcatcaatc gtggcagtga ttttttcttt
     8101 ttgatccgtt tttttaattt tttgcttggt ttcctcgatc gacttcttga tatcagcggc
     8161 ttttgtaaag tcctccgatt taacggcggc ctccttagtt gcctctaatt ttttaacgcg
     8221 ttgatccaat gtctcaacat cagtttgcga atttttagcc gctaaatgag ccgcagtcat
     8281 gtcgatcaaa tcgatagctt tatctggcaa agtgcgttgt ggtatatatt ggattgaata
     8341 atccacagcc gccttcaaaa catcatctgg taatacaaca tgatgatgct tttcgtacag
     8401 ctttttaaca ccttgtaata tacgtaaagt gtcagcggcc gtcggttcat taatcacaac
     8461 atcattgaat cgccgtgcca aagccgcatt tttcaaaata gtattgcgat attcatcttg
     8521 agtcgtagcc ccgattacag tcagctcgcc acgtgacaaa gcaggtttaa tgatatcagc
     8581 caatcctttg ccaccatctt caccaccagt ggcgcccgtg ccgataatct gatgaatttc
     8641 atcgaagaat agaataatat taccagctgc tttaacttcc tttactagct gtttaatatt
     8701 ttcttcaaaa gaaccgcgat attgagttcc tgcttccaaa gacgataaat caatcgaata
     8761 gatttcttta tcttgaatcg tttctggaac tttaccagcc acaattgctt gtgccagacc
     8821 ttcgacgact gcagttttac ctacaccagc atcaccaact aagattggat tatttttcgt
     8881 cctacgactc aaaatttctg cagtttcttg aatctcattc tcacgtccaa tcactggatc
     8941 tagtaatcca tcacgagcct gttccgtcaa attagtccct aacttttcta aaatcccccc
     9001 ttttttaaca gcctgtttac catctttaga tacttctatt gttttattat tttggggtag
     9061 cttaccagtt gctcggtatt gagcaaactc atccggtgtc agcgattgtc cattaactaa
     9121 ataccgtgca cgctccgaat tttgattatc catgcgccga aataattgat tgaaaacatc
     9181 atccatatca ttgttgaaaa aaggatcatt tccgtagaaa tttgccatat tacaacacct
     9241 ccataaaaat ttatatgtgt aacttagtga ccataatatc ctttaaaact acaactgaat
     9301 cgtatcacga tttttatgta tcgttaagta aagtgcttat agaatcaatt agaaataatt
     9361 agaataattt tgtttaaaca aaagagaaat caatttcata aaatgaattg atttccctac
     9421 aaggttccct atttaatagc ccttgataaa gaacttgaat taacaagtta ctttccagac
     9481 caattttaat ttaagagact gcgactcaaa aagcacaccc agtatcaagt taaggccaac
     9541 tagttatcgt taatattgcc acttaaatat caatactagc aatcatgata cacgtgtaaa
     9601 atcataaacc aaaacatatt acatgacgta acggcggtct tgggactgta aactcacagt
     9661 aatgattcta ttgagttgga taaggtgccg atgaccagta attgccataa atgcaattgc
     9721 tttcggtaca atcgtagtga catagccaac tgtctcggcc atctgcccat ttgttttata
     9781 aaaccgtaat gagactcgac atttttgatc atgcgcttgt tgtaatttac aataattatt
     9841 ttcaacactc aaattaaagt ctcccgttca aagaattcag gtttatttat tcgtcagtga
     9901 atctatgtgt ttgtttttct cattgttgac ggcgtaagtc cacattaagg agtcagctat
     9961 tcagtaaaaa ctaaataact agtattcatg ttcagctcag tataatatgc attgatggtt
    10021 actaatcaaa aatcgatctc taaatatcct aattactatg aaactttgaa gttaatttat
    10081 gagaaaaata actcacaaca aaactcatga ttacaacctt gtcatcataa ctagattatg
    10141 aaacattcag cctcctaaat aaaactggta tgcgcgcatg tgcgcatgtg tacagtatac
    10201 tattgccagg tatgtctgaa taaccgtttt aagacttgaa aaactcagct gggtgcttta
    10261 ggacgctttt tgtgcatttt aagacaatat cctaacttca acgccggcat agcttcaatt
    10321 cgtcaatcag tgtcttagtt cctcagctat ttctgttcag aacatcttcc tattacaata
    10381 aaaagcgttg atctcagcag aatttacttc caccaaaacc aacgctaaag tgttattata
    10441 tcaggtattt taaattcatt tcagacatta tattcagcat tacttctact acctaagtaa
    10501 tttagcacgt ttaacatctt caatcgtctt agttcccgct agttgcatat cgatcaacag
    10561 ctcatcatta aggtgactca ctacggaagc gacaccctgc gcaccaccca atgctaatcc
    10621 atagataatc ggccgagcaa gtgccaccag atctgcacca ttggctaacg ccttaaagac
    10681 atgggagcca cgccgaacac cgctatcaaa aattgttggg acgcgcccat taacggcttg
    10741 cgcaatctcg tgtaaaacat caaaggaagc tggaccacca tttaattgcc gaccgccatg
    10801 gtttgaaaca tagatacctt gagcaccagc cccgattgct aacaaggcat cttctggtta
    10861 ctgaatcccc ttcacaataa ctggtaaatt cgtatattct gtaatacgcc gaacatcagc
    10921 tgggctaatc ttttgcgccg cagcagcata gatttctatg atacctttcc ctttaccatc
    10981 cccttcgctg aacttagtca agttagccat tgggattgga aactggaaat tgttgataat
    11041 atcagcttca cgatacccgt caactgttgc atcaacagtc aaaatgattg ccttagcacc
    11101 agccttcact gcttcatcca ataaactctg attgaaattc caatccttgc tcatatataa
    11161 ttggaaaaat tggggcgcac ctttaccagc tgcggcagta tccgcaattg acgttgaaga
    11221 ataagtactc tgagccatga gtgccccaac ttgagccatc ccttcagcag tcgcagcttc
    11281 accccgtgca tgtgccaatc cttgagcggc cgctggagcc atcataatag gcgttttgag
    11341 atctatgcca aaagcctgag tctgtgtgct tggctgttcc atatccgtca atgctcgtgg
    11401 cacaatttga acatggttaa aggccattgt attctgcttt aaagtccatt cgtcttctga
    11461 cccaccacta atatagccaa agcctccgct cgggatgatc tttttagcag ctgcttccaa
    11521 tgatggtaaa tttaaaatcg ttaacttttg ctcacgatca ctctgttcat atccattaat
    11581 aactgtcatt atactaatct cctttacata accctttata attcatttaa taattggcta
    11641 agtgccggtt gatccgcttc agcgatacca tatcgttcac gatacttagc aatcgtatct
    11701 gcatcaaagt tttctggatc tactggaaca aaactagtat caattggatc aacattttta
    11761 atttttgcat caatcacaat tggtagttga ttaccattct gctgtagttg agtaactttc
    11821 tgaaacgttg ctttcaactc tttaaggtta gtcactttaa aaccaatcgc acccatgttg
    11881 tctgccatct tggcccaatc agcaccaatc aagtcaatcc catacggcgc ctgattagcg
    11941 agtaactttt catgttgaat aaagcctaat actttgtttt ctaaaaccac gttaatgact
    12001 ggcaaatgat atttaacttc cgttagtaag tctggcatca ccatggcata accaccatca
    12061 ccagaaatac tccaaacctg cttcttagga taattcaatt gggcggccaa acctgctggc
    12121 aaaccaaaac ccatcgtgcc ataccaagcc gacatcgtaa aagtctgttg cttattcaat
    12181 ggtaactgtc ggattgccca ttccgtatta ttcccaacat ccagaccaaa gacggcatca
    12241 tcagtagcat tgtctttaat agcttctagc accccttcag ccgtcaaccc tccttgatca
    12301 tcagtagcaa ttgtcttgag ccaccggttc cagttttgct tatcacgttg agcagctttc
    12361 aagaacttag ttggcttaat tgtcacttcg gattgaagta atgcttggaa aaattctttt
    12421 gcatctgcaa gaacagtaat atcagcatca tgttgtttgc ctaaatctgc taaattatta
    12481 ttgacttgaa taaacttaat tccttgtggc aagtaacgtg caaatggaaa gttagtacca
    12541 acaaacaaaa ctagatctgc cgcttgcgag acttcaaagg cgggtttagt tcctagtcga
    12601 ccgcgagagc ccatgaaatt aggatggtca gttggcataa taccagttgc tggagccgtc
    12661 gacaaaaccg gcaaactaaa tttttcagaa actgcgataa cttcttgacg cgcattatag
    12721 gcacccttgc caatccataa aacagggtgt tgagcagctt tcaaagccgc tatcgtctgc
    12781 tgaacgtcat ctaatttcgg cattaagacc tgttgactgc cgctaagtga agccgtttta
    12841 aaaccatcaa actcaatatc ttgaccagac aaatcatctg gaataataac aacagaaacc
    12901 gaacgggtcg cgtatgctga tctaattgct tcatcaacca cgtatggaat ctgttcagcc
    12961 gttgtcactt gtttatgaaa ttcggctaca tctgcaaaaa ttggatcttg gttcatttct
    13021 tgaaagaagt tcgtattcat aatggatgtt gctgattgac cgactaaagc tagcaccggt
    13081 acgtgatcca tcttggcatc gtataatccg ttcaagagat gaacggcgcc cggtcctgct
    13141 gaaccaaagc taacaccaat cgtcccagtt aatttagcat ctgccgcggc agctaaagca
    13201 ccaacttctt catgacgtac ttgaatatac ttcaagtggt ctttctcttg gtagaaccca
    13261 tctaccgtgt tattaatcga gtcagctgta ataccataga tatgatcaat gttccagtcg
    13321 actaacactt gtgccaatgc ttgtcctgct ttaattttag tcatttccat taccctcttt
    13381 ttgttgttac ttttttgagc acaactatat cctaaataaa aacttgaccc ttgtcaagtc
    13441 tttatcttaa attatgcttg ttgttgaaca gcgctaatgt catcaataat atcttgcagc
    13501 gtcactcgcg acatacgtgc ctcagcacta ttctgaatat cacaatagta tttttccatc
    13561 actcgcggaa ttaccgaccc gaccggacac gtctccgaag tattatgatc aacgtttaaa
    13621 aaattacgct tagccaccac tgctacatag atatctttca aggtaatatc attgggcgaa
    13681 caagctaatg ttggtctagc aacgccacga accgaagtta acaagcctgc ttttcttaac
    13741 ttactcatca ttcttctgac catggtagga tccgtattta aactactagc aatatgctca
    13801 cttttcagct ggtcatcagt atgcaacgca atatatgcca taatatgcgt cgcatcactt
    13861 aattgtgtat tagccatcta gacacctccc atatccatct ctattgttac ttattttagc
    13921 acatctaaca tgaacataaa agcgattaag gaaataagtt aggcttcttt ccctaatcgc
    13981 aacataagat tatttgataa tctccattaa ttcaatcaaa cttattcaag acatcgatag
    14041 tagctgaatt taaaacccac cctgtccaat ttgatgttgc aaatcatcta agccaaattg
    14101 ttttaaataa gttgaaagtg gttgtaaatc ttgagcttca taccgttgtt taaatgcttc
    14161 aatatcagct gccgaactcg ttgccgaatc taaacgaagc ttttcagcag gcagtggccg
    14221 atctcctgta atcaccgcat caatcagaac tggttcatgc tgagcgattg ctttggcttg
    14281 ttcaaaaaca tcaggtaatt gctcaatctt attaactcga aaagcttgca tgtgcacgcc
    14341 atcggcaatc ttactaaaat caatatcatt gaattcaacg ccaataaaat cattctgatt
    14401 agtatcttcc tgctcatctt tgataaatcc atattggcag ttggtgaaaa caacattaat
    14461 cactggtaaa tggtattgaa cttgcgtcgc caaatcttgc atggtcatcg aagcgccacc
    14521 atcaccggcc agattaaaca cctgccgctc aggataatta agtttggcag caattgctcc
    14581 cggaatacca actcccatcg tagcaaataa gttagaagta atgtgccgat tggacggcgt
    14641 taatttcaaa tgtcgattcg cattcaaatt gatatcacca acatcaatcg aatagattgc
    14701 atcaggctcc gcaattttat taaccgcacg tagcacttga tatgcttgta aaggcccttc
    14761 ctgcttatct tctaatgaag ctagataagc ccgccaattt ttaacattgg ctaaattggc
    14821 ttgccaccaa ggtgtcgact cccgttcaga tacctgtgct aaaattgcag ccagcgtttt
    14881 ttgtgcatca gcaagtaccg caatatctgt tttatgtcgt ttacctaact tagctggatc
    14941 aatatcaatt tgtaagaaat aacgcgtatt tttaaacgct ttggaaactt ctgcaaacgg
    15001 ataattatta ccaacaaata aaacaacgtc ggcttgcgca agtgcctcat tcgccggttt
    15061 ttgtgccacc cgattagcag aacccaaata ggctggataa cgatccgcga caataccctt
    15121 agctggatac gtactcatta atggaatttt caacgtttta ctcaattgtt cgagttcttt
    15181 accagcctta cgagctccaa tgccatagta aataagtggc cgttcagctg cgagtaaagt
    15241 ctgtgtcaat ctcgtcactg cttgaacgtc gggttctggt aataacggcg tttgataact
    15301 attagcggaa gcataccaat cttcagctgg aatctgttgc catggtaaat cgactggaat
    15361 ttgcacaacc gcaacacctt ggtgcgcgta ggcgcgtcga attgcttcgt caataacatg
    15421 tggcaacgtg gcagcattga cggctgttac attataatct gcaacgtccg cataaatcgg
    15481 attctcattc atttcttgga acgtatccat gttcatccca gtagttccaa attgaccaat
    15541 aagtgctaga acagggacat ggtcttcacg cgcatcatat aacccattca taagatgagt
    15601 gccaccaggt cccgctgagc cgaagcaaac cccgatttta cccgttagct tagcatcagc
    15661 agcggcggcc attgcaccaa cttcttcatg ccgtacttga atataatgga ttcgatccct
    15721 ttctgctgat aatgcgtcca taattgaatt aattgaacct ccaggaatac catacaaatg
    15781 atctactccc caagcttcta aaactttaat aactgctgca cctgctagta tgttagtttg
    15841 ttttgtttgt ttcataacca taataaagcc cccatttcat gcacaattta attacgcaca
    15901 atttaataaa cgaatattac catagcaaac gcttacattc aagtggtcat aaactcatgc
    15961 tttttaccac ttaatcacga ttcaaacgca ttgtagatca acaacagcgc tagtctgctt
    16021 gccttgatga accaccatcg ctgttgacag ttagtatctc atacattcat tttttaaaca
    16081 attttagtaa ttagtgtatg ttttacaggg gcatacttcc aacaatgtct gcatgtttag
    16141 aagctagcca ttcttcgaaa actaactacc gctttcaaaa catgacctta actcaactcg
    16201 acacagagca aaataacatc tgccaagtta attattcagc tataatccgt accacgctac
    16261 caactttaaa atcaggataa tcgccctgct caacatataa cgtcccaggc aatttagcct
    16321 cctttgcacc cgtaaaacta atagccgtat ggcctaatct tccaaggtta gtctggactt
    16381 caccaccaac tgctgtaatt tgatagactt gattgtcgac ttcaagtttc attcctgctg
    16441 tgatttgctc acttattggg acaacttcga taataaagca agaaggccgt aatgcgtctg
    16501 gagcttcatc accaaataat actgccatgc caatcgattt aaaatcagca gattccgcac
    16561 ctatttctaa gacctttgtt gaaaagataa ttctctcttt tgtcatcata caatacacct
    16621 caaaccttct aaaaatttat tttgaatata atccaaaact tgcaatccaa gcaataaaga
    16681 cccgcggaac gccgttgata aaccgactat ataacactga tggcacccca acttcaaccg
    16741 tcttag
//
