LOCUS       gnlProkkaNFEIODNI_33   16746 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NFEIODNI_33.
ACCESSION   gnlProkkaNFEIODNI_33
VERSION     gnlProkkaNFEIODNI_33
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 07:47:39
            Original ID  :: gnl|Prokka|NFEIODNI_33
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16746
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..87
                     /locus_tag="ctg33_1"
                     /transl_table=11
                     /translation="MFSHSKTPEIVVQSRGFTSAIEKLDLFV"
     protocluster    1..16746
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[6040:6746]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6041..6746
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..16746
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16746
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(143..487)
                     /locus_tag="ctg33_2"
                     /transl_table=11
                     /translation="MISDILSFTIFGSGAFQIAFLLTAFLGGFIDGLFLYRKSVNWLSV
                     VMTQILVMIFVSLMMDSWLISVLFGTNFKVLLLGRLARVIIQIPLQVIAIFYFIKALEK
                     RHVFDRMRLR"
     CDS             complement(886..1020)
                     /locus_tag="ctg33_3"
                     /transl_table=11
                     /translation="MIKSILKFCLAATLIVSGVLIGGTVLTAKGIDNLGDKLQDKLHG"
     CDS             complement(1037..1282)
                     /locus_tag="ctg33_4"
                     /transl_table=11
                     /translation="MHWLWVLIIGAIIGAIAGAITNKGKSMGWISNIIAGLVGSAIGEA
                     LLGSWGPQLAGMAIVPSIIGGVIVVAITSFVLTRMD"
     CDS             1568..3082
                     /locus_tag="ctg33_5"
                     /transl_table=11
                     /translation="MLAFKLCKSFLVIYVKRAIKMTEKLTTETGQPWANNEHSQTAGAR
                     GPVLMQDYNLLEKLAHFDRERIPERVVHAKGAGAKGFFELENDMGEYTKADLFNGVGKK
                     TPVILRFSQVAGEKGYPDTVRDVRGFALKFYTQQGNYDLVGNNTPVFFVNDPLKFPDFI
                     HSQKRDPKTNRRTQNMQWDFWAHSPESLHQVTYLMGDRGLPASYRTMNGYGSHTFKWVN
                     QNGEQFWVKYHFISDQGVKNMTAQAAEKAMSQDLDYLQDDLYDAIQEKNYPSWTMYVQI
                     LPYEEGLNYKWDIFDVTKVISHKDYPLIKVGKLTLNENPTNNFTDIEEAAMSPANFVPG
                     IEPSPDKLLQGRLFSYKDAQRYRLGANFEDLPVNKPVVPVHNYERDGYMKINNQGAEVN
                     YEPNALHGPEEVPDAALSPDSVRGETRAQPYRYQVDYTTQAGDLYRLMSEPEQERLINT
                     IKDALGQVTLPGVKKLEIKQFYEADKNYGTRVANALGMNIADIISD"
     CDS             complement(3240..3677)
                     /locus_tag="ctg33_6"
                     /transl_table=11
                     /translation="MIRLYTQSSCHSSRVARQWLEAHGIEFKEKNFSVDSPTVQDLKRI
                     LSLTEHGVDDIISARSKDYPEIAPKLPEMPLNEALKLLCDHPKLLRRPIIISDSKIQVG
                     FNEDDIRQFIPRPVRRLKFNALLSRLDGNTGDHIINKRMVE"
     CDS             complement(4033..4776)
                     /locus_tag="ctg33_7"
                     /transl_table=11
                     /translation="MISVYICEDDPKQLQQIRQIITKVIVDQQLDMSICLACQDPHELL
                     DKVNAQQPQKAIYVLDIALNSDINGIQLASQIRDMGRRSKIIFITTHTELSLMVFQYQV
                     EALDFILKDFPDSLYERFSKVLHVAQDRFQTDENDQDDYVQIKIGETVRSINVKSIIFF
                     ESSTSPHKIVVHLDDGELEYYGLLKDVPDLSPNFYRCHKSYVVNLKRIKSLDKHLRRLT
                     MTNGEKVLCSAQANRYLAKWLAKKS"
     CDS             complement(4769..6031)
                     /locus_tag="ctg33_8"
                     /transl_table=11
                     /translation="MLMIVFQELSIYLIIKSLLRNIFFVRLFDVIFLSVCMLMSYIFLA
                     KLGISFSFLMLMMFIFFTWWYVRVLSGALCITFQVFIWSIMVDHICDILTRLMKVPNGY
                     VVVFVILSVVSLIFLNIVMDRTNFSPTFSNQSLNRITALLLMIIYLYIMLSEGLENQFQ
                     VILSNLIILSVVMGLVLVIYNEYLKNVRAKYEVQKQRIQIQNDTRYMNEIEAHYNELRR
                     FRHDYQNMLISIDEYLKTDDLEGLQEYYQKNLAPVSNRVLKEKYNLEDLSRVKVKSIKS
                     ILFSKLSYAQSQEIEVHFDLKEPLIDITVNELDLDIALGIMLDNAIEASVGHADGEIMS
                     AIFIEKNSTVFLIQNNVFEQLPPLWKLKEAGYSTKGKNRGIGLNSLSKIVNRNENMILE
                     TRVLGAVFLQRLTVKRVSQND"
     CDS             complement(6041..6169)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_9"
                     /sec_met_domain="TIGR04223 (E-value: 2.1e-08, bitscore:
                     25.3, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEKMYKVLSHLFQYVGTKQLVMCCHGILFETKIPDELKSKD"
     CDS             complement(6150..6746)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_10"
                     /sec_met_domain="AgrB (E-value: 1.7e-35, bitscore: 113.1,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKPEQKLLLYKLSDRLFAAIQKNLQLERRQALLVKLGIDTVLNV
                     IPKLIITIILALLLHELVPVLVFMGSFLVLRGFAYGRHLKSDLLCTILTIFVFVGVPYV
                     IETGISEVYRLLLSLIFVIIISIFAPADTVKNPITSKSLRKKLKRRAIGLSLILSLLQI
                     VSNNYFGTIILIAMALAALLLMPYERRENYERKNV"
     CDS             complement(6801..7091)
                     /locus_tag="ctg33_11"
                     /transl_table=11
                     /translation="MYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXYVFFSIN"
     CDS             complement(7324..9438)
                     /gene_functions="other (smcogs) SMCOG1223:ATPase (Score:
                     962; E-value: 4.5e-291)"
                     /gene_kind="other"
                     /locus_tag="ctg33_12"
                     /transl_table=11
                     /translation="MANFYGNDPFFNNDMDDVFNQLFRRMDNQNSERARYLVNGQSLTP
                     DEFAQYRATGKLPQNNKTIEVSKDGKQAVKKGGILEKLGTNLTEQARDGLLDPVIGREN
                     EIQETAEILSRRTKNNPILVGDAGVGKTAVVEGLAQAIVAGKVPETIQDKEIYSIDLSS
                     LEAGTQYRGSFEENIKQLVKEVKAAGNIILFFDEIHQIIGTGATGGEDGGKGLADIIKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNDVVINEPTAADTLRILQGVKKLYEKH
                     HHVVLPDDVLKAAVDYSIQYIPQRTLPDKAIDLIDMTAAHLAAKNSQTDVETLDQRVKK
                     LEATKEAAVKSEDFTKAADIKKSIEETKQKIKKTDQKEKITATIDDVAQSVERLTGIPV
                     ADMGANDIEHLKNLDKRLKSKVIGQDEAVEMVAKAIRRNRAGFSEGDQPIGSFLFVGPT
                     GVGKTELAKQLALDMFGNKNAIIRLDMSEYADRTAVSKLIGTSAGYVGYEDNANTLTER
                     VRRNPYSIVLLDEIEKADPQVLTLLLQVMDDGRLTDGQGNVINFKNTIIIATSNAGFGN
                     EALSGDKQRDQSLMDKLAPFFRPEFLNRFNGIVEFSHLTKQDLSQIVDLMLADVQKTLA
                     KKSIKLEVTKAAKDWLMEQGYDEAMGARPLRRVIEQQIRDKVTDFYLDHLDVKNLKADL
                     VDAEIVISAA"
     CDS             complement(9829..10062)
                     /locus_tag="ctg33_13"
                     /transl_table=11
                     /translation="MSVENNYCKLQQAHDQKCRVSLRFYKTNGQMAETVGYVTTIVPKA
                     IAFMAITGHRHLIQLNRIITVSLQSQDRRYVM"
     CDS             complement(10699..11055)
                     /locus_tag="ctg33_14"
                     /transl_table=11
                     /translation="MLAIGAGAQGIYVSNHGGRQLNGGPASFDVLHEIAQAVNGRVPTI
                     FDSGVRRGSHVFKALANGADLVALARPIIYGLALGGAQGVASVVSHLNDELLIDMQLAG
                     TKTIEDVKRAKLLR"
     CDS             complement(11068..11799)
                     /locus_tag="ctg33_15"
                     /transl_table=11
                     /translation="MTVINGYEQSDREQKLTILNLPSLEAAAKKIIPSGGFGYISGGSE
                     DEWTLKQNTMAFNHVQIVPRALTDMEQPSTQTQAFGIDLKTPIMMAPAAAQGLAHARGE
                     AATAEGMAQVGALMAQSTYSSTSIADTAAAGKGAPQFFQLYMSKDWNFNQSLLDEAVKA
                     GAKAIILTVDATVDGYREADIINNFQFPIPMANLTKFSEGDGKGKGIIEIYAAAAQKIS
                     PADVRRITEYTNLPVIVKGIQ"
     CDS             complement(11826..13580)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 471.4;
                     E-value: 6.8e-143)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_16"
                     /sec_met_domain="TPP_enzyme_N (E-value: 2.1e-41, bitscore:
                     132.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.1e-32, bitscore:
                     102.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEMTKIKAGQALAQVLVDWNIDHIYGITADSINNTVDGFYQEKDH
                     LKYIQVRHEEVGALAAAADAKLTGTIGVSFGSAGPGAVHLLNGLYDAKMDHVPVLALVG
                     QSATSIMNTNFFQEMNQDPIFADVAEFHKQVTTAEQIPYVVDEAIRSAYATRSVSVVII
                     PDDLSGQDIEFDGFKTASLSGSQQVLMPKLDDVQQTIAALKAAQHPVLWIGKGAYNARQ
                     EVIAVSEKFSLPVLSTAPATGIMPTDHPNFMGSRGRLGTKPAFEVSQAADLVLFVGTNF
                     PFARYLPQGIKFIQVNNNLADLGKQHDADITVLADAKEFFQALLQSEVTIKPTKFLKAA
                     QRDKQNWNRWLKTIATDDQGGLTAEGVLEAIKDNATDDAVFGLDVGNNTEWAIRQLPLN
                     KQQTFTMSAWYGTMGFGLPAGLAAQLNYPKKQVWSISGDGGYAMVMPDLLTEVKYHLPV
                     INVVLENKVLGFIQHEKLLANQAPYGIDLIGADWAKMADNMGAIGFKVTNLKELKATFQ
                     KVTQLQQNGNQLPIVIDAKIKNVDPIDTSFVPVDPENFDADTIAKYRERYGIAEADQPA
                     LSQLLNEL"
     CDS             complement(13662..14087)
                     /locus_tag="ctg33_17"
                     /transl_table=11
                     /translation="MANTQLSDATHIMAYIALHTDDQLKSEHIASSLNTDPTMVRRMMS
                     KLRKAGLLTSVRGVARPTLACSPNDITLKDIYVAVVAKRNFLNVDHNTSETCPVGSVIP
                     RVMEKYYCDIQNSAEARMSRVTLQDIIDDISAVQQQA"
     CDS             complement(14260..16071)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 494.2;
                     E-value: 8.6e-150)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_18"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.3e-44, bitscore:
                     142.8, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.5e-38, bitscore:
                     123.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVMKQTKQTNILAGAAVIKVLEAWGVDHLYGIPGGSINSIMDALS
                     AERDRIHYIQVRHEEVGAMAAAADAKLTGKIGVCFGSAGPGGTHLMNGLYDAREDHVPV
                     LALIGQFGTTGMNMDTFQEMNENPIYADVADYNVTAVNAATLPHVIDEAIRRAYAHQGV
                     AVVQIPVDLPWQQIPAEDWYASANSYQTPLLPEPDVQAVTRLTQTLLAAERPLIYYGIG
                     ARKAGKELEQLSKTLKIPLMSTYPAKGIVADRYPAYLGSANRVAQKPANEALAQADVVL
                     FVGNNYPFAEVSKAFKNTRYFLQIDIDPAKLGKRHKTDIAVLADAQKTLAAILAQVSER
                     ESTPWWQANLANVKNWRAYLASLEDKQEGPLQAYQVLRAVNKIAEPDAIYSIDVGDINL
                     NANRHLKLTPSNRHITSNLFATMGVGIPGAIAAKLNYPERQVFNLAGDGGASMTMQDLA
                     TQVQYHLPVINVVFTNCQYGFIKDEQEDTNQNDFIGVEFNDIDFSKIADGVHMQAFRVN
                     KIEQLPDVFEQAKAIAQHEPVLIDAVITGDRPLPAEKLRLDSATSSAADIEAFKQRYEA
                     QDLQPLSTYLKQFGLDDLQHQIGQGGF"
ORIGIN
        1 aaatttagtc atagtaaaac ccccgagatt gttgtccaat ctcgggggtt cacttcagca
       61 atagaaaagt tagacttatt tgtttaacga ttgtagcgcg tttcataccg tgttcaacct
      121 ctttttgtag catccatcga tattatctaa gcctcattct atcaaaaacg tgtcgttttt
      181 ctaacgcctt aatgaagtaa aaaatagcaa tcacctgtaa tggtatctga atgatgacgc
      241 gtgccaatct tcccaacaat aacactttaa aattagtgcc aaatagcact gaaattagcc
      301 atgagtccat catcaaacta acaaaaatca ttacaagtat ttgcgtcatc acaacggata
      361 accaattgac tgatttacga tataaaaaca aaccgtcaat aaatccccct aaaaatgcag
      421 ttaacaaaaa ggcaatctga aacgcgccgg aaccaaaaat agtaaagctt aatatatcgg
      481 agatcatctc caagagacca ccccaaatgg gaccatatag ataaccaata caagccatag
      541 acaaaaagcc aaaagataat tgaaaatacg ctggtccgat agcaattttg tataaaataa
      601 cgtctaaggc caataagaaa gccgatgtag tcagcactaa taaattcatt tttggcaact
      661 gaaaaacatt tttcgcaata agtttagaca taggccaatc ctcttttttt gattttaatc
      721 ataccctcat tcttaataaa agtaaatatt acttttattc gattgaaggt agtttaaaat
      781 cgtcgctctt gatttagttc cttgaactca atgatattac tcatactaaa agccactaac
      841 aggtcaacta gtacacccat cagtggctca ttgtaaaatt aatttttatc catgtaactt
      901 atcttgtaat ttatcaccca agttatcaat tcccttagca gtaagtacgg tcccaccaat
      961 aagaacacca cttacgatta aggttgcagc taaacaaaac tttaaaatgc ttttaatcat
     1021 cgcaatcatc tccttactaa tccatccgtg tcagaacaaa tgaggttatc gcaacaacaa
     1081 tcacaccacc aataattgaa ggaacaattg ccattccggc taattgtggt ccccatgatc
     1141 ccaaaagagc ttccccaatt gcagatccaa ccaatccggc aataatatta ctaatccacc
     1201 ccatcgattt acctttatta gtaatagcac ctgcaattgc accaataata gcaccaatga
     1261 tcaaaaccca taaccaatgc ataaaatccc tcctagactt attaaaccgc ttaaatacaa
     1321 taatagaatt acacgaatat ttaagccgat tcataaatga ttacttctta taattatcat
     1381 tttacaatta tcgataatga tagacaaata taacacatta tttaataaat gggtcgctac
     1441 tatttctcat gtgacgattc cgggtggcct agaaaatatc aaacagcttg atagctgatt
     1501 aaaattaaac tacgccacat gaacgattaa cttaactgtg cataatgatt gaagtcactc
     1561 tgttaaggtg ttagcgttta aattgtgcaa gagctttctt gtaatttacg tgaaaagggc
     1621 gattaaaatg acggaaaaat taacgacgga aaccggccaa ccatgggcta acaatgaaca
     1681 ttcccaaacg gcaggagctc gtggtcccgt attaatgcaa gactataatc ttttggaaaa
     1741 actagcccat tttgatcgtg aacgaattcc agaacgggtc gttcatgcta agggggccgg
     1801 agcaaaaggt ttttttgaac ttgaaaacga catgggggaa tatactaagg cagacttatt
     1861 taatggtgtc ggtaagaaaa ctcccgtaat cttaaggttc tcacaagttg ccggtgaaaa
     1921 aggttatcct gacaccgttc gagacgtgcg cggttttgcc ttaaaatttt atactcagca
     1981 aggcaattat gatctcgttg gaaacaacac accggtcttt tttgtaaacg accctttaaa
     2041 atttcctgac ttcatccatt cacaaaaacg ggatcctaaa acgaaccgtc gtacgcaaaa
     2101 tatgcaatgg gatttttggg ctcattctcc agaatcattg caccaggtca cttatttaat
     2161 gggcgaccga ggtcttcctg cgtcctatcg aaccatgaat ggttacggtt cccatacttt
     2221 taaatgggtt aatcagaatg gcgaacagtt ttgggttaag tatcacttca tctcagacca
     2281 aggcgttaaa aatatgactg ctcaagcagc tgaaaaagca atgagccaag atttagatta
     2341 cttacaagat gacttatatg atgcaattca agaaaaaaat tacccatcat ggacgatgta
     2401 tgtccaaatc ttgccatatg aggaaggtct aaactataaa tgggacattt ttgatgtcac
     2461 taaagtcatc tcccacaaag actatccact aattaaagtc ggcaaactaa ctttaaatga
     2521 gaatcccact aataacttta ccgatattga agaggcggcc atgtcgccag caaattttgt
     2581 tcctggtatc gaaccatctc ccgacaaatt actacaaggt cgcctattct cctataaaga
     2641 tgcacagcga tatcggttag gtgccaactt tgaagattta cccgtgaaca agccggttgt
     2701 tccagttcat aattatgaac gtgatggtta catgaaaatt aataatcaag gtgctgaggt
     2761 caactacgag cctaatgcac tgcatgggcc agaagaggtg ccggatgccg cactttcacc
     2821 tgattctgtt cgtggtgaaa cacgcgcaca gccttatcgc tatcaagttg attacacaac
     2881 tcaagcaggc gacctatatc gcttaatgtc agaacccgag caagaacgct taattaatac
     2941 tatcaaagat gcgttaggcc aagttacttt gcctggtgtc aaaaaactcg aaatcaagca
     3001 attttatgag gccgacaaaa actacggtac acgcgtggct aatgctctgg gaatgaatat
     3061 tgctgatatt atcagtgatt aatattttga ccggatgtta tccagcgcga tattattttt
     3121 gttataaaga atgatgatgc cgtctcatgg ttattaacta aagagcgaca ggttagactc
     3181 atatcgtgta agtctagctt gtcgctcttt aattaacaaa aaatcttaga tatagcttac
     3241 tactcgacca tccttttatt aataatgtga tcccctgtat taccatctag acgactcaac
     3301 aatgcattga actttagtcg ccgaactggt cgtggaataa attggcgaat atcatcttca
     3361 ttaaagccaa cttgaatttt actatcacta atgatgatag gccgacgtaa caacttcgga
     3421 tgatcacaca acaatttaag tgcctcattc aatggcattt cgggtaactt aggcgcaatt
     3481 tcaggatagt ctttagatcg agctgagata atatcgtcta caccatgttc ggttaaactc
     3541 aaaatacgtt ttagatcttg caccgtgggc gaatcaacac taaaattttt ctccttgaac
     3601 tcaatcccat gtgcttccaa ccattgccgt gcaactctag aagaatgaca gcttgattgt
     3661 gtatataacc taatcattcc taatctgccc ctctctcgtt aaaattcatc acagcgtatt
     3721 gatcgacatt aacttctgcc tgtcacaaca tcctttaaac taaacgcatt cgttactgtc
     3781 atgaccaatc caataccccg tgaacacatc tttattatag gctctgaaca agggacatac
     3841 cgaccgtttt aagacgaata atctgaggat aatcgtttta agtacacttt taaacggttt
     3901 aggaaagaac gaacccagta cacgtaatgc taacaaatat cactgcaatt tctaatcgaa
     3961 taacgctgaa ttttcatcgc gtagcacata aaaagtcgcc tactaattta acaggcgact
     4021 tccttggaac tattatgact ttttagcaag ccatttagct agataacgat tagcttgtgc
     4081 agaacaaagc actttttcac catttgtcat ggttaatcgt cgcaagtgct tgtccaatga
     4141 cttaatgcgt ttcaagttaa caacatatga cttatgacac ctatagaaat taggactcaa
     4201 atcaggaacg tcctttaaca gtccatagta ttctaattca ccatcatcca aatggactac
     4261 gattttatgg ggactggttg aactttcaaa aaatataatg cttttaacat taattgatct
     4321 gaccgtctca ccaattttta tttgaacata gtcgtcttgg tcattttcat cggtttgaaa
     4381 acgatcttgc gccacgtgta aaaccttgct aaatcgctca tacaaggaat ctggaaaatc
     4441 cttaagaata aaatctaatg cctcaacttg atattgaaac accatcaaag ataactccgt
     4501 gtgtgtcgtg ataaaaataa tcttgctgcg acggcccatg tcacgaatct ggctagctag
     4561 ttgaatacca ttaatatctg aattaagggc aatatctaac acatagattg ccttttgagg
     4621 ctgctgtgca ttaaccttgt ctaacaattc gtggggatct tggcatgcta aacagatact
     4681 catgtctagc tgttgatcga cgattacctt agtaatgatt tgccgtattt gttgtaattg
     4741 tttcggatca tcttcgcaaa tgtagacact aatcattctg agatactcgc ttcaccgtca
     4801 agcgttgtaa gaataccgct cctaagactc tggtttcgag tatcatgttc tcattgcgat
     4861 taacaatctt acttaaacta ttcaatccaa tcccccgatt cttgccctta gtggaataac
     4921 ctgcctcttt cagcttccat aagggtggta actgttcaaa aacattgttt tgaatcaaga
     4981 acaccgtact atttttttcg ataaaaatgg cactcataat ctctccatca gcatgtccta
     5041 ccgatgcttc gattgcatta tccaacataa tccctaatgc aatgtctaaa tccaattcat
     5101 taacagtaat gtcaattaat ggttccttta aatcaaaatg aacttcaatc tcttgcgatt
     5161 gtgcatagct caacttacta aataggatac tcttaatcga cttcactttg acccgactca
     5221 aatcttcaag attatatttt tcttttaaca cccgatttga aaccggtgca agattctttt
     5281 gataatattc ttgtaaacct tctaaatcat cagttttcaa atattcatct atcgaaatca
     5341 acatattctg atagtcatgt ctgaaacgtc gcaactcatt atagtgagct tcgatttcat
     5401 tcatatagcg agtatcattt tgtatttgta ttctttgctt ttggacttca tatttggctc
     5461 ttacattttt taaatattcg ttataaatca ccaatactaa ccccattaca actgacaata
     5521 taattaaatt acttaatata acctggaact gattttccag accttcactc aacataatat
     5581 acaagtatat tatcattaat aatagtgcgg ttatgcgatt taagctctga ttactaaacg
     5641 tgggactgaa attcgtgcga tccattacaa tattaagaaa aattaagctt acgacactca
     5701 atatgacaaa cactaccaca tacccattag gaactttcat taaacgagtt aatatatcac
     5761 aaatatggtc aaccataatc gaccatatga acacttgaaa tgttatacat agtgcaccgc
     5821 ttagaactcg tacataccac caagtgaaaa atataaacat cattaacatt aaaaaagaaa
     5881 aactaattcc taactttgct aaaaaaatat aactcatcag catacagacg gataagaata
     5941 taacatcaaa aagtctcaca aaaaatatat ttctcaacaa agatttaatt atcaaataga
     6001 tagataattc ttggaagaca atcattaaca tatatctaca ctaatccttg ctttttaatt
     6061 catcaggaat tttagtttcg aataatatcc catggcagca cataaccaac tgtttagtac
     6121 ctacgtattg aaaaagatgg ctaagtactt tatacatttt ttctttcata attttccctc
     6181 ctttcatagg gcattagtaa taaagcggct aatgccatcg caattaaaat gattgtgcca
     6241 aaataattat tactaactat ttgtaacaaa ctcaaaatta atgacaatcc aattgcccgt
     6301 cgctttaatt tttttctcaa tgacttcgat gtaataggat tctttaccgt atcagctgga
     6361 gcaaaaatac ttatgattat tacaaatatt aaacttaata acaatctgta tacttcagaa
     6421 ataccagttt caatcacata cggcacaccc acaaacacaa agatagttaa tatcgtacat
     6481 aacaaatccg atttcaagtg acgtccatag gcaaagccac gcaaaactaa aaaactaccc
     6541 ataaaaacta acactgggac caactcgtgt agcagcaacg ctaagataat agtaattatc
     6601 agcttaggaa taacatttaa tacagtatca atgcctagtt taactagtaa tgcctgccgt
     6661 ctttctagtt gaagattctt ttgaatcgca gcgaataacc gatcgcttaa tttataaagc
     6721 aatagttttt gttctggctt ttccatatcc cactcctata atgctcaaat acatacctgt
     6781 atcaacagtt taaaacagta ttaattaatt gaaaagaata cataannnnn nnnnnnnnnn
     6841 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6901 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7081 nnnnnataca tcagtttaat tattcatacg aaactaaagt ttcatgtaaa aagatcgtta
     7141 atataaatca gtttcatcga tactccccct taatttttcc ttagattaca agtcaaacta
     7201 gacttaattt cactaattca cattactcaa tagattaata tcaaatggtg aaaatcaacg
     7261 aaaagaggag atctatcaag caatctcctc ttacataaag ttatttatga acactgattt
     7321 aagctaagct gccgatatca caatctcagc atccactaaa tcagccttca agtttttgac
     7381 atctaagtgg tcaaggtaga aatccgttac cttgtcacga atttgttgtt caattactcg
     7441 ccgtaatggc cgcgcaccca tcgcttcatc atagccttgt tccatcagcc aatctttggc
     7501 cgctttagtt acctcaagtt tgatggattt tttggctaac gttttttgta catccgccaa
     7561 catcaaatcg acaatttgac ttaagtcttg cttagtcaga tgtgaaaatt ccacgattcc
     7621 attaaaacgg ttcagaaatt ctgggcggaa aaatggtgct aacttatcca ttaatgactg
     7681 atctcgttgc ttgtcaccac ttaatgcttc attaccaaag ccagcattag aagtagcgat
     7741 aataatcgta tttttgaaat taatgacatt gccttgtcca tccgttaagc gcccatcatc
     7801 catcacttgt aacagtaacg ttaatacttg tggatcagcc ttttcaattt catctaataa
     7861 tacaatggaa tatggattac gccgaacccg ttcggttaga gtattagcat tatcttcata
     7921 gcctacgtat ccagccgagg taccaattaa tttcgacaca gctgtacgat cagcatattc
     7981 actcatatct agccgaataa tcgcattttt atttccaaac atatctaagg ctaattgctt
     8041 agctaattca gtctttccta cgccagttgg gcccacaaac agaaaacttc caattggctg
     8101 atcaccctct gaaaagcccg cacggttacg ccgaattgcc ttcgctacca tttcaaccgc
     8161 ttcatcttga ccgattacct tacttttcag acgcttatca agatttttca agtgctcaat
     8221 atcattagcg cccatatcag caactggtat accagttaaa cgttcaaccg attgtgccac
     8281 atcatcaatc gtggcagtga ttttttcttt ttgatccgtt tttttaattt tttgcttggt
     8341 ttcctcgatc gacttcttga tatcagcggc ttttgtaaag tcctccgatt taacggcggc
     8401 ctccttagtt gcctctaatt ttttaacgcg ttgatccaat gtctcaacat cagtttgcga
     8461 atttttagcc gctaaatgag ccgcagtcat gtcgatcaaa tcgatagctt tatctggcaa
     8521 agtgcgttgt ggtatatatt ggattgaata atccacagcc gccttcaaaa catcatctgg
     8581 taatacaaca tgatgatgct tttcgtacag ctttttaaca ccttgtaata tacgtaaagt
     8641 gtcagcggcc gtcggttcat taatcacaac atcattgaat cgccgtgcca aagccgcatt
     8701 tttcaaaata gtattgcgat attcatcttg agtcgtagcc ccgattacag tcagctcgcc
     8761 acgtgacaaa gcaggtttaa tgatatcagc caatcctttg ccaccatctt caccaccagt
     8821 ggcgcccgtg ccgataatct gatgaatttc atcgaagaat agaataatat taccagctgc
     8881 tttaacttcc tttactagct gtttaatatt ttcttcaaaa gaaccgcgat attgagttcc
     8941 tgcttccaaa gacgataaat caatcgaata gatttcttta tcttgaatcg tttctggaac
     9001 tttaccagcc acaattgctt gtgccagacc ttcgacgact gcagttttac ctacaccagc
     9061 atcaccaact aagattggat tatttttcgt cctacgactc aaaatttctg cagtttcttg
     9121 aatctcattc tcacgtccaa tcactggatc tagtaatcca tcacgagcct gttccgtcaa
     9181 attagtccct aacttttcta aaatcccccc ttttttaaca gcctgtttac catctttaga
     9241 tacttctatt gttttattat tttggggtag cttaccagtt gctcggtatt gagcaaactc
     9301 atccggtgtc agcgattgtc cattaactaa ataccgtgca cgctccgaat tttgattatc
     9361 catgcgccga aataattgat tgaaaacatc atccatatca ttgttgaaaa aaggatcatt
     9421 tccgtagaaa tttgccatat tacaacacct ccataaaaat ttatatgtgt aacttagtga
     9481 ccataatatc ctttaaaact acaactgaat cgtatcacga tttttatgta tcgttaagta
     9541 aagtgcttat agaatcaatt agaaataatt agaataattt tgtttaaaca aaagagaaat
     9601 caatttcata aaatgaattg atttccctac aaggttccct atttaatagc ccttgataaa
     9661 gaacttgaat taacaagtta ctttccagac caattttaat ttaagagact gcgactcaaa
     9721 aagcacaccc agtatcaagt taaggccaac tagttatcgt taatattgcc acttaaatat
     9781 caatactagc aatcatgata cacgtgtaaa atcataaacc aaaacatatt acatgacgta
     9841 acggcggtct tgggactgta aactcacagt aatgattcta ttgagttgga taaggtgccg
     9901 atgaccagta attgccataa atgcaattgc tttcggtaca atcgtagtga catagccaac
     9961 tgtctcggcc atctgcccat ttgttttata aaaccgtaat gagactcgac atttttgatc
    10021 atgcgcttgt tgtaatttac aataattatt ttcaacactc aaattaaagt ctcccgttca
    10081 aagaattcag gtttatttat tcgtcagtga atctatgtgt ttgtttttct cattgttgac
    10141 ggcgtaagtc cacattaagg agtcagctat tcagtaaaaa ctaaataact agtattcatg
    10201 ttcagctcag tataatatgc attgatggtt actaatcaaa aatcgatctc taaatatcct
    10261 aattactatg aaactttgaa gttaatttat gagaaaaata actcacaaca aaactcatga
    10321 ttacaacctt gtcatcataa ctagattatg aaacattcag cctcctaaat aaaactggta
    10381 tgcgcgcatg tgcgcatgtg tacagtatac tattgccagg tatgtctgaa taaccgtttt
    10441 aagacttgaa aaactcagct gggtgcttta ggacgctttt tgtgcatttt aagacaatat
    10501 cctaacttca acgccggcat agcttcaatt cgtcaatcag tgtcttagtt cctcagctat
    10561 ttctgttcag aacatcttcc tattacaata aaaagcgttg atctcagcag aatttacttc
    10621 caccaaaacc aacgctaaag tgttattata tcaggtattt taaattcatt tcagacatta
    10681 tattcagcat tacttctact acctaagtaa tttagcacgt ttaacatctt caatcgtctt
    10741 agttcccgct agttgcatat cgatcaacag ctcatcatta aggtgactca ctacggaagc
    10801 gacaccctgc gcaccaccca atgctaatcc atagataatc ggccgagcaa gtgccaccag
    10861 atctgcacca ttggctaacg ccttaaagac atgggagcca cgccgaacac cgctatcaaa
    10921 aattgttggg acgcgcccat taacggcttg cgcaatctcg tgtaaaacat caaaggaagc
    10981 tggaccacca tttaattgcc gaccgccatg gtttgaaaca tagatacctt gagcaccagc
    11041 cccgattgct aacaaggcat cttctggtta ctgaatcccc ttcacaataa ctggtaaatt
    11101 cgtatattct gtaatacgcc gaacatcagc tgggctaatc ttttgcgccg cagcagcata
    11161 gatttctatg atacctttcc ctttaccatc cccttcgctg aacttagtca agttagccat
    11221 tgggattgga aactggaaat tgttgataat atcagcttca cgatacccgt caactgttgc
    11281 atcaacagtc aaaatgattg ccttagcacc agccttcact gcttcatcca ataaactctg
    11341 attgaaattc caatccttgc tcatatataa ttggaaaaat tggggcgcac ctttaccagc
    11401 tgcggcagta tccgcaattg acgttgaaga ataagtactc tgagccatga gtgccccaac
    11461 ttgagccatc ccttcagcag tcgcagcttc accccgtgca tgtgccaatc cttgagcggc
    11521 cgctggagcc atcataatag gcgttttgag atctatgcca aaagcctgag tctgtgtgct
    11581 tggctgttcc atatccgtca atgctcgtgg cacaatttga acatggttaa aggccattgt
    11641 attctgcttt aaagtccatt cgtcttctga cccaccacta atatagccaa agcctccgct
    11701 cgggatgatc tttttagcag ctgcttccaa tgatggtaaa tttaaaatcg ttaacttttg
    11761 ctcacgatca ctctgttcat atccattaat aactgtcatt atactaatct cctttacata
    11821 accctttata attcatttaa taattggcta agtgccggtt gatccgcttc agcgatacca
    11881 tatcgttcac gatacttagc aatcgtatct gcatcaaagt tttctggatc tactggaaca
    11941 aaactagtat caattggatc aacattttta atttttgcat caatcacaat tggtagttga
    12001 ttaccattct gctgtagttg agtaactttc tgaaacgttg ctttcaactc tttaaggtta
    12061 gtcactttaa aaccaatcgc acccatgttg tctgccatct tggcccaatc agcaccaatc
    12121 aagtcaatcc catacggcgc ctgattagcg agtaactttt catgttgaat aaagcctaat
    12181 actttgtttt ctaaaaccac gttaatgact ggcaaatgat atttaacttc cgttagtaag
    12241 tctggcatca ccatggcata accaccatca ccagaaatac tccaaacctg cttcttagga
    12301 taattcaatt gggcggccaa acctgctggc aaaccaaaac ccatcgtgcc ataccaagcc
    12361 gacatcgtaa aagtctgttg cttattcaat ggtaactgtc ggattgccca ttccgtatta
    12421 ttcccaacat ccagaccaaa gacggcatca tcagtagcat tgtctttaat agcttctagc
    12481 accccttcag ccgtcaaccc tccttgatca tcagtagcaa ttgtcttgag ccaccggttc
    12541 cagttttgct tatcacgttg agcagctttc aagaacttag ttggcttaat tgtcacttcg
    12601 gattgaagta atgcttggaa aaattctttt gcatctgcaa gaacagtaat atcagcatca
    12661 tgttgtttgc ctaaatctgc taaattatta ttgacttgaa taaacttaat tccttgtggc
    12721 aagtaacgtg caaatggaaa gttagtacca acaaacaaaa ctagatctgc cgcttgcgag
    12781 acttcaaagg cgggtttagt tcctagtcga ccgcgagagc ccatgaaatt aggatggtca
    12841 gttggcataa taccagttgc tggagccgtc gacaaaaccg gcaaactaaa tttttcagaa
    12901 actgcgataa cttcttgacg cgcattatag gcacccttgc caatccataa aacagggtgt
    12961 tgagcagctt tcaaagccgc tatcgtctgc tgaacgtcat ctaatttcgg cattaagacc
    13021 tgttgactgc cgctaagtga agccgtttta aaaccatcaa actcaatatc ttgaccagac
    13081 aaatcatctg gaataataac aacagaaacc gaacgggtcg cgtatgctga tctaattgct
    13141 tcatcaacca cgtatggaat ctgttcagcc gttgtcactt gtttatgaaa ttcggctaca
    13201 tctgcaaaaa ttggatcttg gttcatttct tgaaagaagt tcgtattcat aatggatgtt
    13261 gctgattgac cgactaaagc tagcaccggt acgtgatcca tcttggcatc gtataatccg
    13321 ttcaagagat gaacggcgcc cggtcctgct gaaccaaagc taacaccaat cgtcccagtt
    13381 aatttagcat ctgccgcggc agctaaagca ccaacttctt catgacgtac ttgaatatac
    13441 ttcaagtggt ctttctcttg gtagaaccca tctaccgtgt tattaatcga gtcagctgta
    13501 ataccataga tatgatcaat gttccagtcg actaacactt gtgccaatgc ttgtcctgct
    13561 ttaattttag tcatttccat taccctcttt ttgttgttac ttttttgagc acaactatat
    13621 cctaaataaa aacttgaccc ttgtcaagtc tttatcttaa attatgcttg ttgttgaaca
    13681 gcgctaatgt catcaataat atcttgcagc gtcactcgcg acatacgtgc ctcagcacta
    13741 ttctgaatat cacaatagta tttttccatc actcgcggaa ttaccgaccc gaccggacac
    13801 gtctccgaag tattatgatc aacgtttaaa aaattacgct tagccaccac tgctacatag
    13861 atatctttca aggtaatatc attgggcgaa caagctaatg ttggtctagc aacgccacga
    13921 accgaagtta acaagcctgc ttttcttaac ttactcatca ttcttctgac catggtagga
    13981 tccgtattta aactactagc aatatgctca cttttcagct ggtcatcagt atgcaacgca
    14041 atatatgcca taatatgcgt cgcatcactt aattgtgtat tagccatcta gacacctccc
    14101 atatccatct ctattgttac ttattttagc acatctaaca tgaacataaa agcgattaag
    14161 gaaataagtt aggcttcttt ccctaatcgc aacataagat tatttgataa tctccattaa
    14221 ttcaatcaaa cttattcaag acatcgatag tagctgaatt taaaacccac cctgtccaat
    14281 ttgatgttgc aaatcatcta agccaaattg ttttaaataa gttgaaagtg gttgtaaatc
    14341 ttgagcttca taccgttgtt taaatgcttc aatatcagct gccgaactcg ttgccgaatc
    14401 taaacgaagc ttttcagcag gcagtggccg atctcctgta atcaccgcat caatcagaac
    14461 tggttcatgc tgagcgattg ctttggcttg ttcaaaaaca tcaggtaatt gctcaatctt
    14521 attaactcga aaagcttgca tgtgcacgcc atcggcaatc ttactaaaat caatatcatt
    14581 gaattcaacg ccaataaaat cattctgatt agtatcttcc tgctcatctt tgataaatcc
    14641 atattggcag ttggtgaaaa caacattaat cactggtaaa tggtattgaa cttgcgtcgc
    14701 caaatcttgc atggtcatcg aagcgccacc atcaccggcc agattaaaca cctgccgctc
    14761 aggataatta agtttggcag caattgctcc cggaatacca actcccatcg tagcaaataa
    14821 gttagaagta atgtgccgat tggacggcgt taatttcaaa tgtcgattcg cattcaaatt
    14881 gatatcacca acatcaatcg aatagattgc atcaggctcc gcaattttat taaccgcacg
    14941 tagcacttga tatgcttgta aaggcccttc ctgcttatct tctaatgaag ctagataagc
    15001 ccgccaattt ttaacattgg ctaaattggc ttgccaccaa ggtgtcgact cccgttcaga
    15061 tacctgtgct aaaattgcag ccagcgtttt ttgtgcatca gcaagtaccg caatatctgt
    15121 tttatgtcgt ttacctaact tagctggatc aatatcaatt tgtaagaaat aacgcgtatt
    15181 tttaaacgct ttggaaactt ctgcaaacgg ataattatta ccaacaaata aaacaacgtc
    15241 ggcttgcgca agtgcctcat tcgccggttt ttgtgccacc cgattagcag aacccaaata
    15301 ggctggataa cgatccgcga caataccctt agctggatac gtactcatta atggaatttt
    15361 caacgtttta ctcaattgtt cgagttcttt accagcctta cgagctccaa tgccatagta
    15421 aataagtggc cgttcagctg cgagtaaagt ctgtgtcaat ctcgtcactg cttgaacgtc
    15481 gggttctggt aataacggcg tttgataact attagcggaa gcataccaat cttcagctgg
    15541 aatctgttgc catggtaaat cgactggaat ttgcacaacc gcaacacctt ggtgcgcgta
    15601 ggcgcgtcga attgcttcgt caataacatg tggcaacgtg gcagcattga cggctgttac
    15661 attataatct gcaacgtccg cataaatcgg attctcattc atttcttgga acgtatccat
    15721 gttcatccca gtagttccaa attgaccaat aagtgctaga acagggacat ggtcttcacg
    15781 cgcatcatat aacccattca taagatgagt gccaccaggt cccgctgagc cgaagcaaac
    15841 cccgatttta cccgttagct tagcatcagc agcggcggcc attgcaccaa cttcttcatg
    15901 ccgtacttga atataatgga ttcgatccct ttctgctgat aatgcgtcca taattgaatt
    15961 aattgaacct ccaggaatac catacaaatg atctactccc caagcttcta aaactttaat
    16021 aactgctgca cctgctagta tgttagtttg ttttgtttgt ttcataacca taataaagcc
    16081 cccatttcat gcacaattta attacgcaca atttaataaa cgaatattac catagcaaac
    16141 gcttacattc aagtggtcat aaactcatgc tttttaccac ttaatcacga ttcaaacgca
    16201 ttgtagatca acaacagcgc tagtctgctt gccttgatga accaccatcg ctgttgacag
    16261 ttagtatctc atacattcat tttttaaaca attttagtaa ttagtgtatg ttttacaggg
    16321 gcatacttcc aacaatgtct gcatgtttag aagctagcca ttcttcgaaa actaactacc
    16381 gctttcaaaa catgacctta actcaactcg acacagagca aaataacatc tgccaagtta
    16441 attattcagc tataatccgt accacgctac caactttaaa atcaggataa tcgccctgct
    16501 caacatataa cgtcccaggc aatttagcct cctttgcacc cgtaaaacta atagccgtat
    16561 ggcctaatct tccaaggtta gtctggactt caccaccaac tgctgtaatt tgatagactt
    16621 gattgtcgac ttcaagtttc attcctgctg tgatttgctc acttattggg acaacttcga
    16681 taataaagca agaaggccgt aatgcgtctg gagcttcatc accaaataat actgccatgc
    16741 caatcg
//
