LOCUS       gnlProkkaKBFHEIFM_1    22954 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KBFHEIFM_1.
ACCESSION   gnlProkkaKBFHEIFM_1
VERSION     gnlProkkaKBFHEIFM_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 07:22:27
            Original ID  :: gnl|Prokka|KBFHEIFM_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 257530
            Orig. end    :: 280484
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22954
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12954]"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12954
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     cand_cluster    1..22954
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="interleaved"
                     /product="sactipeptide"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..22954
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     protocluster    235..21467
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10234:11467]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      10235..11467
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="2"
     CDS             414..953
                     /locus_tag="ctg1_268"
                     /transl_table=11
                     /translation="METNKPTLYWSLLMFKDWNFYIASTLKGLVFVGSQNKPIEELFEW
                     AKKRFPGSLLVEDDDKLEPYAVEITQYLEGKRKNFTVPVEYAGTQFQLAVWNALCEIPY
                     GQTKSYSDIANEINKPAAVRAVGAAIGANPVLITVPCHRVIGKNGSLTGYRGGFEMKTL
                     LLDLEKRASSEMDVPH"
     CDS             1464..2981
                     /locus_tag="ctg1_269"
                     /transl_table=11
                     /translation="MLVSLSLSSLLTLFFIMLMASGISGLLFLHPRVPLSFVRIHIGIL
                     ALPLLVSLLILANSGVSGNVGPWHLDSLACLMTFFVLAIGFIIQRFSVRYLMGDRSYRK
                     YFTLFTFTTGAASMTWLSGDLRLMVLFWGATLVGLTLLIRLNSAWQVASEAAKISGRLF
                     LLSWFSLFFAMMWLFHATGQWQLSLVVTNESLAGLGEWERTGIQLLIVLAVIIPAAQWP
                     FQRWLVESIVAPTPVSAIMHAGLVNAGGIILTRFSPLFHGGIASIILLLLAGISVLIGT
                     GISLVQVDYKRQLVGSTIGQMGFMLIQCALGAYIAAIIHLILHGLFKATLFLQAGSAVG
                     RHEVSARTNERTSYLWVMAGRILSLVIGVAFWLTAPGDGYHLISALILGWSLSVSWTQL
                     VAFGEGRIGRIAGLTVLGVAALVYFIIHNLFYKWLHTTIFQSVQPPMSAVMIVVCLLLF
                     GSALGTWVARHRSSVFFAVLYLWLVRLGEAKPKSVESHPDYLKQYIS"
     CDS             2996..5608
                     /locus_tag="ctg1_270"
                     /transl_table=11
                     /translation="MGITSVLTKDNVKKIDTDIDVQERDLNVFITSASRVIAPLWPIST
                     FAARNPWMGLENQPFDQVASWLKNTRDVDIYPSASMIRSAKNKGEIDEDFVEMGLQRWL
                     DSHSYHIPRDVAERFCHAALKLDPLPSDLLSSHELEKLVSECSGLDHIENVFMQPLSSY
                     IENQDGERLVNILDHHVIKWSKLYLDDSQAGWTMPNREEGFYRAWQHLIQYDPALSKKQ
                     RERVKGWPKEAHLALQEALFALEIPESEIQTYLEGHLLSLPGWAGMMLWRSQQSSHEHA
                     LLTEYLAVRISMEWALIKPYLPLNERSKKTISIAPLIAAWIHWGGLTLEEWSQMTAIEQ
                     NEYLSFAYSFDEKLRKKLWLEAWEQTYTDRLSQKIISKQRETGGEKSALAQLAFCIDVR
                     SEPFRRQLEKEGPFETIGIAGFFGVPIATCELGSKHSHASLPIIQKPQNNIKEFADEDV
                     FKKYNQRKQAIHSLSHTFKTMKQNALSSLLLPELSGPWLTLQMAARSFVPRKAGRFIRN
                     LREAWLRKPDTKLSLHHDATEAEIPVGFTDEEKVNYARQALKMMGLTENIAPLVVICGH
                     GSQSTNNPYSAALDCGACGGAAGGFNARVLAALCNLSEVREALLTEGIKIPEDTVFAAA
                     EHNTTVDELHWLYVPELSEAAQEAFEQIEAVMPKVRHHVNAERLAQLPNFQSKLKNPKA
                     EANRFAEDWSEIRPEWGLARNAAFIIGKRELTQDCDLEGRAFLHNYDWKQDESGELLAN
                     IIAGPGTVAQWINLQYYASTVAPHYYGSGNKATQTVTAGLGVMQGNASDLLAGLPWQSV
                     MESDHEAYHSPLRLLILIQAPREYVERLLNNDSAFLQKVQNGWVRLANIDPEGCWESW"
     CDS             5685..6212
                     /locus_tag="ctg1_271"
                     /transl_table=11
                     /translation="MNVNQNKKVLFLTDIENGLEPILQEATNTSAENMLTIQSYGASIS
                     HPYGEIMRSVIFAIYQEDVEEIFVVGTKDKKTSAGNGLTQLETMKDKIQTLDYLFQNCK
                     PEFLGGTVDEWLNENSSDTIEKSVDMIRHHPLVPSHVKVRGLLVHHKDRKPSIVEVPDV
                     KTGQALPDHCLS"
     CDS             6276..6566
                     /locus_tag="ctg1_272"
                     /transl_table=11
                     /translation="MSANLTDFVTKTIEDMNSFDRENMECMKKLIRKAIDFYHLKSYEE
                     VEETHSGNVRFLHVHSMMEENMLSKMIVVTRNGKTDLDIEGVYEGYVVREY"
     CDS             6624..6998
                     /locus_tag="ctg1_273"
                     /transl_table=11
                     /translation="MKKSKGSIESEISKSITQWEKDYLGRGSVSVKTDILRDMIIVNLK
                     GILTPAEYVVCGSKEGMLSIKQTRSELVESGIEGLKDIILKITGEKVKSFHTDLSSRTG
                     ERVMVFKLCNDLEKNLEKIL"
     CDS             complement(7101..7274)
                     /locus_tag="ctg1_274"
                     /transl_table=11
                     /translation="MFSNIVQVTNHQHQIHVFKIDVKKHPLITTADVRSFDRNNMTVYY
                     ELTSLYVRLGYE"
     CDS             7481..7783
                     /gene_functions="regulatory (smcogs) SMCOG1058:ArsR family
                     transcriptional regulator (Score: 67.7; E-value: 1.1e-20)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_275"
                     /transl_table=11
                     /translation="MEPIEVFKALSNESRLQILQWLKEPDRHFAPHEGIDMNTIGVCVS
                     QITDKLKMTQSTASQYLTILLRAGLIKAERIGKYTYYKRDEEAIGKLADFLKTEI"
     CDS             7910..9082
                     /gene_functions="transport (smcogs) SMCOG1184:major
                     facilitator transporter (Score: 335.6; E-value: 5e-102)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_276"
                     /transl_table=11
                     /translation="MSNTWKIYILAIVSFLVGTSEYIISGILDQIAHTLGITLAAAGQL
                     ITIFSLVYALSTPILMALTASMDRRKLMMYALGLFVFGNVLAFVLPGYGWFIAARIIMA
                     MGAGVVVVTALTIAAKIASEGKQGSAIATVVMGFTASLIIGVPLGRMIAVALGWKSVFG
                     AIALLGLIAMVVIFFTLPHTEGDKPVPLLQQLALFKKRKVAMGLSITFFWLGGYSVAYT
                     YLSPYLLNISGINGKLLSGVLLIFGIASLVGSKFGGFSTDKWGVPFTLVGGMTLHIVTL
                     ILLSLVTHSYIGVLVILILWSFAAWSTGPTQQFHLATIEPEMSGVLLSMNQSMMQFAMA
                     VGAGIGGVFVENVSLASITWVGALGVMIAIIASLLIFNSQPKQALKDINQ"
     CDS             10001..10168
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: TIGR04404"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_277"
                     /sec_met_domain="TIGR04404 (E-value: 4.5e-37, bitscore:
                     123.7, seeds: 3, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRNQKEWESVSKKGLMKPGGTSIVKAAGCMGCWASKSIAMTRVC
                     ALPHPAMRAI"
     CDS             10235..11467
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_278"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     2.6e-14, bitscore: 51.4, seeds: 13, tool:
                     rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.7e-21, bitscore: 74.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 4.9e-06, bitscore: 24.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 5e-05, bitscore: 21.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYDRVKDFDLPELAVHLQPHGAVMIDRKSMFYFRLSGRGAQLAF
                     LLSKNKNLHKTARIWEIMKKEEMSADQLKEELSAHPFTEAWTEGLLDQPLHVSGSLDSY
                     LPISCTLQLTNACNLSCSFCYASSGKPYPEELSSEQWILVMQKLAAHGVADITLTGGEA
                     KLIKGFKELVVVASSLFTNVNVFSNGLNWRDEEVELLSHLGNVSVQISIDGMDNTHDQL
                     RGRKGGFKESMNTIKKLSEANIPVIVAMTINESNADEVSDVVEQCANAGAFIFRAGKTL
                     SVGRATEGFKALDIDFEEMVQIQLREARHKWGDRLNIIDWEHEESSFTTDFCTPGYLAW
                     YIRADGYVTPCQLEDLPLGHILEDSMADIGSPARLLQLKCEAKNCKCIGKIELSEPDLP
                     FQKEVKAGIQE"
     CDS             11464..12954
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: skfc"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_279"
                     /sec_met_domain="skfc (E-value: 1.2e-287, bitscore: 952.7,
                     seeds: 3, tool: rule-based-clusters)"
                     /sec_met_domain="Abi (E-value: 9.7e-13, bitscore: 46.3,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSLSLVFWSILAVVGLLLFIKFKPPTIASLLLSKDEAKEISIQF
                     IKEFVGIDVENWDFYSVYWYDHDTVNKLHHLGILKKNRKVLYDVGLVESWRVRFVHKNQ
                     SFVVGVNANREITFFYADVPKKSLSGKFEQVSPETLKQRLMASPDGLWSRANMTGTGKK
                     EEDFREVSTYWYIAEAGDIRLKVTVELQGGRISYIGTEQEILTDQMSKVIRDEQVESTF
                     GVSGMLGSALAMILAILILVFMDVQTSIIFSLVLGLLIIICQSLTLKEDIQLTIVNAYD
                     ARMSVKTVSLLGILSTLLTGLLTGFVVFICSLAGNALAGDFGWKTFEQPIVQIFYGIGA
                     GLISLGVTSLLFNLLEKKHYLRISPELSNRTVFLSGFTFRQGLNMSIQSSIGEEVIYRL
                     LMIPVIWWMSGNILISIIVSSFLWAVMHQVTGYDPRWIRWLHLFIFGCFLGVLFIKFGF
                     ICVLVAHFIHNLVLVCMPLWQFKLQKHMHHDQPKHTSL"
     CDS             12973..13695
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 178.8; E-value:
                     2.3e-54)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_280"
                     /transl_table=11
                     /translation="MQLMQVQNLSKYYRNGDGVEHLSFSIQRGEIVALLGPNGAGKTTT
                     IRCLTGLYKPDKGDILIEGSPPGHINVQKKVALIPDQPYLYPALTAAEHIQFRARGYHP
                     GKKDVKERVYHALKEVHLEEKANQLCGQLSRGQKQRVVLAGAIVQDALLYILDEPTVGL
                     DIPSKQWLSNWLKTKTDQGCSAFVSTHSLEFVIETADRVILIRDGKLMQDLYVPQFEEE
                     QAEWRKEVIRLLGEWSDE"
     CDS             13760..15103
                     /locus_tag="ctg1_281"
                     /transl_table=11
                     /translation="MPFLIMLLFVGAIGFQVSFVSRSTTWDMSIAGWVLTGVFILYTAF
                     GLFSNRLPSQMADIIWLYGTATSFSKVVYSVLFFSVTWKALLWIISAIFGDVLIVLLSG
                     DHNNLLGRSIIFVGLFFVAEVWLMSVSCARTVKKMKRVYVLVFLLMLGIYSICLYQFFF
                     LQHSSGIWESIARFISGVGLVFDTLSPLYVVVFIGIITVSFMTIAFSSRQVEMKESLVK
                     EAEFWEEFQERQFGSGQIIQKPKTTWWGLQGLNGIWSFLWLELLLFKKYLFFHSIHTVM
                     LSGVFYVVIFMYPEWFYLLFFLIVSAVMLSSYYSGIVRHSQSGTLHLFPGALWKKIIIL
                     ELTNTVWLYILYCVSITFMAVGNLVYWYIYGLGIYIWFMTIRLFAFTHTNRNDIKLSLP
                     QYYKSFFMALGLSGICLYVIHLLTADWYTLVVVVCIGSLSWCLFYRFR"
     CDS             15150..15665
                     /locus_tag="ctg1_282"
                     /transl_table=11
                     /translation="MNSNGDKLSLSVQNLANTNEITIVQAIGELKKSGKDAIPVLVEAL
                     KEEGSLCNIAAAVLGEFGEDASEAAEELSCLLKSHAEDTRMAAAISLMRIGKPSLPFVI
                     KIAQESEGQSCFWASWCIAWIDPSCIEPKMYKCLKYEHEHPSGIVAPFAAEEALGKLIA
                     FQLKDKED"
     CDS             15670..16095
                     /locus_tag="ctg1_283"
                     /transl_table=11
                     /translation="MKDEQMLTEWPSHLPWLNQSQNDFTFPSDTYLLLYFWSMSCPNCH
                     QLTDKVLQDIKDMNVKVIGVHVPYIEEEKSMEVVLTYALDRGLAIPIVLDQNYEIVTTC
                     HVQGIPSFCLLSQYGQIITKTMGDVGWDKMLKKIAGL"
     CDS             16343..17320
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_284"
                     /sec_met_domain="PF00561 (E-value: 5.7e-07, bitscore: 27.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTLWKVLKIVFVSLAALVLLVSVSVFIYHHFQLNKEAALLKGKG
                     TVVDVDGKKMNVYQEGSGKDTFVFMSGSGIAAPAYEMKGLYSKFSKENKIAVVDRAGYG
                     YSEVSHDDRDIDTVLEQTRKALMKSGNKPPYILMPHSISGIEAMYWAQKYPKEIKAIIA
                     MDIGLPQQYVTYKLSGVDRLKVRGFHLLTSIGFHRFIPSAVYNPEVIRQSFLTDEEKEI
                     YKAINFKQFFNADMEHELLQSYQNGSKSVNLPAPKETPVLILDAVSDQNRHSKYAIQNR
                     KDYEAFAAQFNTADIKELRGTHSIYLYQPDQIYKLSMEFMRKVR"
     CDS             17322..17993
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 126.9; E-value: 1.4e-38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_285"
                     /transl_table=11
                     /translation="MKGYRILIVEDDVMIGDLLQKILQREGYRVIWKTDGADVLSVIQK
                     VDLVIMDVMLPGEDGYQMSAKIKKLGLGIPVIFLSARNDMDSKLQGLQIGEDYMVKPFD
                     PRELLLRMRNMLEHHYGTFTQIKHLYIDAVTKKVFNESLHDEVLFTAIERKIFFYLYEN
                     RDSILTKEHFFEYLWQLEDRNPNIVNVHIKKIRAKINDQAGEMIENIYGEGYRLNTVVK
                     K"
     CDS             17990..18976
                     /locus_tag="ctg1_286"
                     /transl_table=11
                     /translation="MKLKTKYQLLLFTAVISVPMLLLAVSVLMSVIYDSMFKPMNHGMP
                     FHRSFAYPAMIVVFLISLLLLAFLFSKSIHSLLHKINLLNQTIRHLASDQRVPDKIEVK
                     RADEIGELIKSVNLLIERTTYRELELRQQEEIKKELLQKLRHDINTPLTALRLQLFYLE
                     DQCHGQAVFESLYQQIEYISELTNEFNLYSAETLESSYIVNEEVRLNELLETAVKKWDY
                     LYSMSGIELHYKPADQDVIWMSNTLWMERLFDNIFQNTLRHSKAKKMEVTIEHGDVFIR
                     DDGIGFDRNESSEGLGLKIIEDTCRLLAITYELHTNDNGTGFLFSKE"
     CDS             19035..19298
                     /locus_tag="ctg1_287"
                     /transl_table=11
                     /translation="MNIICLKKSSKRLSTSQAVLVTDIADTGITAAAGADIIAATAAVR
                     AKEDTTTVMAAVIVTNAGATAAVNPKKVLVPLLGQGFFYVTD"
     CDS             complement(19283..20053)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 112.1;
                     E-value: 5.4e-34)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_288"
                     /sec_met_domain="Pkinase (E-value: 7.8e-32, bitscore:
                     108.6, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALKLLKKLLFDRPLKNGVILNHQYKIEECLGMGGYGLVYLCTDI
                     LAQTPYVLKQLRPTKAKKEKEKVRFQQEIKLLKNIHHPQIPGFIDEFIIDGQAYYVMQF
                     IEGENIEELLFFRKQPFTELMALQLISQLLEIIEYLHDRLIFHSDIRTPNIIINDGRLC
                     LIDFGLAKQLTPEEMEEIKVRKQDDFFDLGETLLFFLYSQYKGKKKKNGTWLEELTLTK
                     EVTLLLKRLLGIEEEYQHTASIREDLNRAIQSVT"
     CDS             complement(20139..20996)
                     /locus_tag="ctg1_289"
                     /transl_table=11
                     /translation="MVKKWLIQFAVMLSVLSTFTYSASAVGVTAITGNNSFDTAMPIGY
                     WKNKNIDTTILEAGQDEAYFTFTANKGEKVYMRSTYQSAYTGMKIEIYDKNRIPVSQGT
                     EVINPNTFSSFIYANADAQNTTDTFYVKVSRGTYTGNMYFTLSIEDRIKSGSGTFQFSG
                     VAENKGNTSLSPSGSDSSVIKVDLTNQSGIPRDAIVTRVQTTATQTPSQGNTRHLIMTS
                     ENNEWSRALVNSSTSGSYDISLSDQLSVAKVWSFKYNTLATARSTMSNVKAKIDYEYDV
                     TKQF"
     CDS             21128..22312
                     /locus_tag="ctg1_290"
                     /transl_table=11
                     /translation="MRLNRQFIRTQLIAQNILSKNAPAKRENATENPAAVLEKAYSRLK
                     SQSSTGGINQFNYSKTSVSGNSGTFSKVYQSANDRTVTDTGEETVIQSQNPYESESDIR
                     IKILDEKYSRMNAINKTKSDPLGYIKDKYQNSKSPYFRSDLSAAERQAAYDNETEWLFK
                     GKAQNYNLQDAVFRNVTFHGEVEAENEKVYQRGQVNQQLQVLLNRNHIHIPEGTELTFT
                     ITPIDYQVRVSGTDDQDLIKQIEQVLQSGDNSKELFLHIMKSQSSDSAQFSEEAYQKYQ
                     AAREMYEVTGYHLKDLEVIDGRYVTPEGRDLMDVYKEELEKDPVQKQTASYAISYYRSE
                     LSKIAEAGYNAIPDFILSIDYSNGSLRDVGQSKSYGTGDTGWLEALKRQTGVNY"
ORIGIN
        1 ctttccaaac gcagaacaag ctctccgcgc aaattttcgc ccttgtaaac gttgcaagcc
       61 cactaatgaa aaaatgcctg atagcgagtg ggttgattta attactgaat acattgataa
      121 aaatttcaca gaaaaattaa cgctagaatc gttagcagat atttgtcatg ggagtccgta
      181 tcatatgcat cgaacattta aaaaaattaa aggcattacg ctggttgagt atatacaaca
      241 agttagagta cacgcggcta aaaagtattt gattcagaca aataaagcga ttggagatat
      301 cgctatatgt gtgggtatag ctaacgcgcc ttattttatt actttattta aaaagaaaac
      361 tggacagaca ccagcacaat ttcgtcaaat gagtaaaatg gaggaaacgt acaatggaaa
      421 caaataaacc aaccctttat tggtctttac taatgttcaa ggattggaat ttttatattg
      481 cttcaacttt aaaggggctt gtgtttgtag gttcacagaa caaaccaatc gaggaattgt
      541 tcgaatgggc taagaaacgc tttccgggaa gtcttcttgt tgaagatgat gataagcttg
      601 aaccctatgc cgttgaaatc acacaatatc tagaaggaaa gcggaaaaac tttactgttc
      661 cagttgagta cgccggtacg caatttcagc tagcagtctg gaatgcactt tgtgaaattc
      721 cttatggaca gacgaaatcc tattccgaca ttgcaaatga aataaataaa ccagcagctg
      781 ttcgtgctgt aggtgcggct attggggcta atccggtatt aattactgta ccgtgccatc
      841 gtgtaatagg aaagaatggc tcattaactg gctatcgggg cggattcgaa atgaagacac
      901 tgctcctcga tctggaaaag cgagcttcat ctgaaatgga tgttcctcat tgaaagtgaa
      961 tcatctataa tgggttggat tcttttagag gaccagttta ctgataaact tgacaacttt
     1021 taaaatttag catatcttat acgtaactta ataatcgatg ccgatgttta tttttccttt
     1081 taaaatatgt aggcctttag cattcttttc atatttaatt ttaaatattg ataggatgaa
     1141 aaagcatcct aactaaaaag gaagagaaac ataagtcgat ttatttgata atcaggacta
     1201 tattaaagga aatgaaaaca tagcataaag taaagaccaa taataaggta gctcttcaaa
     1261 aaacttcgct gaagttagtt gaagtgaagc cgacaatttt caggattcaa tgatctaaca
     1321 taatcattga aattttgaag ttgtcggctt ttttgttgga aaaaaataga gataaataaa
     1381 aattgaaata aataatagac aaatatgatc tgattgaaag gtcttttgac caataatgag
     1441 ttttaaaaaa gggagaattt agaatgttag tttcgctgag tttgtcatca ttattaacat
     1501 tattttttat tatgcttatg gcttctggga ttagtggact attgttttta catccgcgtg
     1561 tacccttgag ttttgtccgc attcatattg ggatcttggc tttaccactt ttggtttcct
     1621 tactgattct tgccaatagt ggtgtgagtg gaaatgttgg cccttggcac ttagattcct
     1681 tagcttgttt aatgactttc tttgttcttg caattggatt catcattcag cgtttttctg
     1741 tacgttactt aatgggggat cgatcttatc gaaaatattt tacgcttttt actttcacaa
     1801 caggagctgc ttcaatgaca tggttaagtg gtgatctccg cttgatggtt ctattttggg
     1861 gagcgactct tgttggatta accttactta ttaggttaaa cagtgcttgg caagtggcta
     1921 gtgaagcagc caaaatttct ggtcggttat ttttgttaag ttggttttct ttgttttttg
     1981 cgatgatgtg gctttttcat gccacaggtc aatggcagct atcattggtt gtaacaaatg
     2041 aaagtttagc tgggctggga gaatgggaga gaacagggat tcagctattg attgtattag
     2101 cagtgattat tcctgcagct caatggccgt tccaaagatg gttggttgag tctattgttg
     2161 ctccaacccc tgtttctgca attatgcatg caggtttagt aaatgcagga ggaataatac
     2221 taactcgatt ttcacctcta tttcatggtg gtatcgcttc gattatctta cttctgcttg
     2281 ctggcatttc tgtattgatt ggaactggaa ttagtttagt ccaggttgat tataaacgtc
     2341 agttagtagg ctccacgatt ggacaaatgg ggtttatgct cattcagtgt gcattaggcg
     2401 cctatatagc agccattatt catcttattt tacatggttt attcaaagct acgttgtttc
     2461 tacaagctgg ttcagcagta gggcgtcatg aagtatcggc tcgcactaat gaaagaacat
     2521 cctatttatg ggtcatggct ggtcggattt tatccttagt tataggtgtt gctttttggc
     2581 tcactgctcc tggagacggg tatcacttaa tcagtgcgct gatcttaggg tggtcattgt
     2641 ccgtttcttg gactcagctt gtcgcttttg gagagggccg aattggccga attgccggct
     2701 taactgtttt aggagtagca gccctcgtat attttatcat tcataacctt ttctataagt
     2761 ggctgcatac aaccattttt caaagtgttc aacctccaat gtcagctgtc atgattgtcg
     2821 tatgtctctt actatttggc agtgctttag gtacgtgggt tgctcgtcat cgttcttccg
     2881 tttttttcgc ggtactctat ctttggttag ttcgattagg tgaagcaaaa ccaaagtcag
     2941 tagagagtca cccagactac cttaaacaat atatttcata aggagctaat ctgagatggg
     3001 cattacatcc gtattaacga aagataatgt aaaaaagata gatacagata ttgatgttca
     3061 agaaagggat cttaacgttt tcattacatc tgccagccga gtgattgcgc cactttggcc
     3121 tatttctaca tttgctgcac gtaatccgtg gatgggactt gaaaaccaac cttttgatca
     3181 ggttgcaagt tggttgaaaa acactcgcga tgttgatata taccctagtg cgtctatgat
     3241 ccgttcagca aagaataaag gtgagattga tgaagatttt gtggaaatgg ggctgcagcg
     3301 ttggcttgat tcacattcct atcacatccc acgggacgtg gcagagcgat tttgtcatgc
     3361 tgcattaaag ttagatcccc tgccttccga ccttttatca tcacatgagc tggagaaatt
     3421 agtaagtgaa tgtagtggat tggatcatat cgagaatgtg tttatgcaac cactaagttc
     3481 gtatatagag aatcaagatg gtgaaaggct agtcaatata ctagatcatc atgtcattaa
     3541 gtggagtaaa ttatatcttg atgactctca agcaggctgg acaatgccta atcgtgagga
     3601 aggtttttat cgtgcttggc agcatctcat tcaatatgat ccagcactta gcaaaaagca
     3661 gcgagaaagg gtaaaaggtt ggccgaaaga ggcacatttg gctttacagg aagctttatt
     3721 cgcactagaa atcccagagt cagaaatcca gacttatctt gaaggtcatt tactttcatt
     3781 acctggatgg gcagggatga tgctttggcg ctcccagcaa tcgagccacg aacatgcact
     3841 cctaacagaa tacttagcgg ttcgaatatc catggagtgg gctcttataa agccatactt
     3901 acctttgaat gaacgatcta agaaaacaat ttcaattgct ccccttatag cagcttggat
     3961 tcattggggt gggcttacat tagaagaatg gtcacagatg acggccattg aacaaaacga
     4021 atatttatca tttgcctaca gctttgatga gaaacttcgc aagaaacttt ggttagaagc
     4081 ttgggaacaa acgtacactg atcgattaag ccagaagatc atctcgaaac aacgtgaaac
     4141 cggcggtgaa aaatctgcat tagctcaatt agcattctgc atcgatgtac gatcagaacc
     4201 ttttcgtcgt caactagaaa aagaaggccc gtttgaaacg attggtattg ctggtttctt
     4261 cggggtgccg attgcaactt gtgaacttgg cagtaaacac agtcatgctt cgttaccgat
     4321 catacaaaaa ccgcaaaata atataaaaga gttcgcagat gaggatgtat tcaaaaaata
     4381 caatcaacgg aagcaagcaa ttcattcttt aagccatacc tttaaaacga tgaagcagaa
     4441 tgcgctttcg agcttactac tgcctgagct aagcggacct tggcttactc tgcaaatggc
     4501 agcccgtagc tttgtgccaa gaaaggcggg tcgtttcatt cgtaatctcc gtgaggcttg
     4561 gttgcgcaaa cctgatacaa aactctcgct tcatcatgat gctacagagg cagaaatacc
     4621 tgtgggtttt actgatgaag aaaaagtgaa ctatgctcgc caagcattaa aaatgatggg
     4681 gttaacagaa aacatcgcac cattggtcgt gatttgcggg catggcagtc aaagtactaa
     4741 taatccttat tctgcagccc ttgattgtgg tgcctgcggt ggagcggccg gtggattcaa
     4801 tgcaagagtt ttagctgctt tatgtaatct atcagaggta cgagaagctc ttttaactga
     4861 aggaattaaa atccctgagg atacggtttt tgcagcggct gaacataata caacagtaga
     4921 tgaattacat tggctttatg taccagagct ttccgaagct gcacaagaag catttgaaca
     4981 aattgaagcc gttatgccga aagtgagaca tcatgtaaac gcagaacgtc tagcccaatt
     5041 accgaatttc caatcgaagc taaaaaatcc gaaggctgag gcaaaccgat ttgcggaaga
     5101 ttggagtgag atacgtccgg aatggggact ggctcgtaat gccgctttta ttatcggtaa
     5161 acgtgaacta actcaggatt gtgatttgga aggcagagcc tttctccata attatgattg
     5221 gaagcaggat gaaagcggtg aactcctagc aaatattatt gcaggacctg gaactgtagc
     5281 ccaatggatt aatttacaat attacgcatc aacggtagca cctcattatt atggcagcgg
     5341 aaataaagca actcaaaccg ttactgcagg tctcggcgtt atgcagggga atgcaagcga
     5401 cttgttagcc ggactgcctt ggcaatccgt catggaatca gatcacgagg cctatcattc
     5461 tcctcttcgt ttattgatac tcatccaagc acctagagaa tatgtagaac ggttattaaa
     5521 taatgactca gcatttctgc aaaaagttca aaatggatgg gtccgactgg ctaatattga
     5581 tccagaagga tgttgggaaa gctggtaatg atgaatctaa gcatttatca aatggatttg
     5641 ttattcaaaa taaaaatgat aaacataagg aagaggtgtg ctgtatgaat gtaaaccaaa
     5701 ataaaaaagt attatttttg acggatattg aaaacggttt ggagcctatt ttacaagaag
     5761 cgactaacac ttctgcagag aacatgttga ctatacaaag ctatggtgcc agtatttcac
     5821 atccttatgg agaaatcatg aggtctgtta tttttgcgat ttaccaggaa gatgttgagg
     5881 agatttttgt agtaggaaca aaagataaga agacttccgc aggtaatgga ctaactcaac
     5941 ttgaaacaat gaaagataaa atacaaacat tggattatct ctttcaaaat tgcaagcctg
     6001 aatttttagg tggtacggtc gatgaatggc taaatgaaaa tagcagtgac accattgaaa
     6061 aaagtgttga tatgattcga catcatccac tagtgccgtc acatgttaaa gttcgaggtt
     6121 tactcgttca tcataaggat agaaaaccct caatcgtgga ggttcctgat gttaaaactg
     6181 gtcaagcctt acctgatcat tgcttgtcat gatgaaatgc aggtttaact tctaaacgca
     6241 cccatatatg gagaaagcag ttctaaggag attgtatgag cgctaattta actgattttg
     6301 tcacgaaaac aatagaggac atgaactcgt ttgatcgtga aaatatggaa tgtatgaaaa
     6361 aactaattag aaaagcaatt gatttttatc atctaaagtc ttatgaagaa gttgaggaaa
     6421 cccattcagg aaatgttcga tttttgcatg tccactctat gatggaagaa aatatgttat
     6481 ccaaaatgat agtggtcaca agaaacggta aaactgattt ggatattgaa ggtgtatatg
     6541 aaggatatgt tgtaagagaa tattaatgag acgaaatcac aaatagaata tgccaatttt
     6601 tttgctcagg agatgtatta gatatgaaaa agtcgaaggg ttctattgaa tcagagatca
     6661 gtaagtccat tactcaatgg gagaaggatt atcttggacg ggggtctgta tctgttaaga
     6721 ctgatatact gcgggacatg atcatcgtca atttaaaagg gattttaaca ccagccgaat
     6781 atgtagtttg tggatcaaaa gagggtatgt tatctatcaa acaaactcgt tcagagttag
     6841 tcgaatcagg tatagaaggc cttaaggata ttatcttaaa aataaccgga gaaaaagtga
     6901 aaagttttca tactgattta agctcccgga caggtgaacg agtgatggta tttaaattat
     6961 gtaatgatct agagaaaaat ttggaaaaga tcttataatc taaagaaaat aaatgttttg
     7021 acggtatgga atttgttgtg aattgaacat aaagaactgc cgattctttt gttttacaat
     7081 tatagtatca ttgataactt ttattcatat cctaagcgga cataaagaga tgtcaattca
     7141 tagtacactg tcatgttatt cctgtcgaaa gatctaacat ccgctgttgt tatgagcgga
     7201 tgttttttta catctatttt aaatacatga atttgatgct ggtgattagt cacttgaaca
     7261 atatttgaaa acatccttgt cacctgccgg gttcccccaa gtgttttgtg aaatgattat
     7321 gagaccaatt tcgtaaagct tgctgataaa tttaagcggt gaacaaaatt gatatgctgt
     7381 cttcagtttc atttcacgga attagtcaga gataaacctt taattaaata tatccaaaaa
     7441 acggattgac atatcgaaat ataacgatat aataatcgat atggaaccaa ttgaagtatt
     7501 caaagcctta tcaaatgaat caaggctgca aattttacaa tggctgaagg agcccgatcg
     7561 tcattttgca ccccatgaag ggattgatat gaacacaatc ggggtatgtg tcagtcaaat
     7621 aacagacaaa ttgaaaatga cgcaatcgac agcttctcaa tatcttacca tccttttaag
     7681 agccggccta attaaggcgg agcgaatcgg aaagtacacg tattacaaaa gagatgaaga
     7741 agccattggg aaacttgctg actttcttaa aacagagata taaaaataaa catcaaaaga
     7801 tgtttatttt tacaccatac atatcgacat attacgatgt gtttattttt tataataaca
     7861 tatcgataat tcgtgatatg tttattaatg attaaggagt gaatgtttta tgtctaacac
     7921 ttggaaaatt tatattttag ccattgtcag ctttttagtt ggaacctcag agtacatcat
     7981 ttccggaatt ttggatcaaa ttgctcatac tctcgggatc actttagctg ccgcgggcca
     8041 gcttattacc attttctcac ttgtatatgc tctttctaca cccatactta tggcgttgac
     8101 agcaagtatg gatagacgca aattgatgat gtatgcccta ggtttgtttg tgttcggtaa
     8161 tgtcctggct tttgtactgc ctggttatgg atggtttatt gcagcgcgga tcattatggc
     8221 gatgggagca ggtgtggttg ttgtcaccgc attaacgatt gccgctaaga ttgcatcgga
     8281 agggaagcag ggaagtgcca tcgctacggt cgtgatggga tttaccgctt ctttaatcat
     8341 tggtgttccg cttggaagaa tgatagcagt agcattaggc tggaagtctg tatttggagc
     8401 aattgctttg ttgggattga tcgcaatggt cgttattttc tttactcttc cgcatactga
     8461 aggggataag cctgtgcctt tgcttcaaca gcttgctctt ttcaaaaaac ggaaagtggc
     8521 tatgggatta tcaatcactt tcttctggct cgggggatat tctgttgctt acacttattt
     8581 gtcaccgtat ctcttgaaca tctcaggtat aaacggcaag ctgcttagcg gtgttttgct
     8641 tatatttgga attgccagtt tggttggatc aaaatttggg ggatttagca ccgataaatg
     8701 gggagtgccc tttacactcg ttggtgggat gacgttgcat atcgtcacac tgattcttct
     8761 gtcacttgtt actcattcct atatcggagt gttggtgatt ctcatattat ggtcgtttgc
     8821 cgcatggtcc accggtccga cacagcaatt tcacctggct acaatagaac cggaaatgtc
     8881 tggtgttttg cttagcatga atcagtcaat gatgcaattc gccatggcgg tcggcgcagg
     8941 aataggaggg gtttttgtgg aaaacgtatc attggcctcg attacttggg ttggtgcgtt
     9001 aggggttatg attgccatta ttgcatcatt gctgattttc aattcgcaac cgaaacaagc
     9061 gctaaaagat atcaatcaat aatttcgaaa gatctaacat ccgctcgtta tacaagcggg
     9121 tgttttttta agcgttcaaa gtcagtccat gcatgagccg tccaagggcc gacatcgttc
     9181 tgtatgtgtc gaaggcgcac tggagctgaa agagatttct taaggctttg ccggcggcga
     9241 gctgaagtac ggtacgattg ccttgatcga acactggaaa cacaagagca tgtaaacctg
     9301 aacatccgcg taaacgtcaa ggaagttgcc acttggggag taaacacttg catcatctcg
     9361 ctgaaaggcc tagacaatgc ggatgacaat tcgtattgcc ggaagtaaac acagcgcttg
     9421 ctcttttccg ttgtcgattg cagctgattg cttactaatg ctgccctgca tctcggttgt
     9481 gatgtcgata agcagcgtaa ccttgtgaag aggtgttact gtggagtaag atgtttaacc
     9541 cctttggata ttttagccga aggggttttt agtatagata tttgatttaa attacaggag
     9601 acttcattca tttaactaaa gtcattgctt tcttaatcac taaagtttat ttgaaaataa
     9661 tctcttgatt taatttcctc gaagagattg tttgtcaatc tattaggcat cagaattttt
     9721 ataacagaat ggatcgtctt tttgaggttt tgtttataga acaagaaaat attcaaaaca
     9781 taagtggaaa attaggggtg agctcctgtt tttctcgaga ggatagcttg tcagcttttc
     9841 tatttttaaa gggttaaaat attctattta tactaattaa tgttattttt aggataatat
     9901 acaaaatccc ccttacttcg acaattgcaa tctggtatta tcgtatcgca tgggagctat
     9961 gtcaatagac tctatgcaaa aattgagagg aggtttactt atgaaaagga accaaaaaga
    10021 atgggaatct gtgagtaaaa aaggacttat gaagccggga ggtacttcga ttgtgaaagc
    10081 tgctggctgt atgggctgtt gggcctcgaa gagtattgct atgacacgtg tttgtgcact
    10141 tccgcatcct gctatgagag ctatttaaca tttgagaata gggagttgag cgtatttgct
    10201 tatactcctt attttctctt aagggggatt ttatatgtca tatgatcgtg ttaaagattt
    10261 tgatttgcca gagttagcgg ttcatttaca gcctcatggt gctgtaatga ttgatagaaa
    10321 aagtatgttt tatttcagac tcagtggacg tggagcacag ttggcgtttc tgttatcaaa
    10381 aaacaaaaat cttcataaaa cggcacgtat ttgggagatt atgaaaaaag aagagatgag
    10441 tgctgaccaa ttaaaagaag agcttagtgc ccatccattt acggaggctt ggacggaagg
    10501 gctgttagat cagcctttac acgtttcggg ttcgctagat tcatatttac ctattagttg
    10561 taccttgcag ttgacaaatg cttgtaattt aagctgttcg ttttgctatg ccagctcagg
    10621 taaaccatat cctgaggaac tatctagtga acaatggata ttggttatgc aaaagttagc
    10681 agcccatgga gttgctgata ttacgctgac cgggggtgaa gcaaagctga tcaaagggtt
    10741 taaagaatta gtcgttgttg caagttcgtt gtttaccaat gtgaatgtat ttagtaatgg
    10801 attgaactgg cgagatgaag aagttgaatt acttagtcac ttaggcaatg tttctgtaca
    10861 gattagtatt gatggtatgg ataatacaca tgaccaatta agaggcagaa aaggcggctt
    10921 taaagaaagt atgaatacca ttaaaaaatt atcagaagca aacattccag tgattgtcgc
    10981 tatgaccatt aatgagtcca atgctgatga agtatcagat gtggtggagc aatgtgccaa
    11041 tgcgggtgct tttatctttc gtgcaggaaa aacgttatct gttggacgtg cgacagaagg
    11101 ctttaaggct ttggatattg attttgaaga aatggttcaa atacagctta gggaagcacg
    11161 tcataaatgg ggagatcgcc tgaacataat tgattgggag cacgaagaga gttcgttcac
    11221 aacagatttt tgtacaccag gatatcttgc ttggtatata agagcagatg gatacgtaac
    11281 tccttgccaa ttagaagatt tgccgctagg gcatatttta gaagatagca tggctgacat
    11341 tggttcacct gctcgtttgc ttcagttaaa atgtgaagct aaaaattgca aatgtatagg
    11401 gaaaattgag ctatctgaac cggacttgcc ttttcaaaaa gaagtcaagg cagggattca
    11461 ggaatgaata gtctatcatt ggtgttctgg agtattttag cagttgttgg attactgtta
    11521 tttattaaat tcaaaccccc aacaattgct tcactactct taagcaaaga tgaggcaaaa
    11581 gaaataagca ttcaatttat aaaagagttt gttgggatag atgtagagaa ctgggatttt
    11641 tattcggtat attggtatga ccacgataca gtaaataaac ttcatcactt aggcatactt
    11701 aagaaaaata gaaaggtttt atatgatgtt gggttggtcg aatcatggag agtccgtttc
    11761 gttcacaaga atcaatcatt tgtagttggt gtcaatgcca atcgagaaat tacttttttt
    11821 tatgcggatg ttccgaaaaa gtccctttcg gggaagttcg aacaagtttc tccagagaca
    11881 ctcaagcaga ggttaatggc ttcacctgat ggactttggt ctagagcaaa tatgactggt
    11941 actggtaaaa aagaggagga ttttcgcgag gtcagtactt attggtacat agcagaagcg
    12001 ggagatattc ggctcaaggt gactgttgaa ttacagggcg gccgaatttc ttatattggt
    12061 actgaacaag aaatactaac agatcaaatg agtaaagtca ttcgagatga acaagtggaa
    12121 tcgacattcg gagtatctgg tatgctgggt tcagctttag cgatgatcct tgcgattctc
    12181 atccttgtat ttatggatgt gcaaacaagc ataatcttca gtcttgttct gggtttgttg
    12241 attataatat gccagtcatt gacgctgaaa gaagatattc aattaacaat tgtaaatgct
    12301 tatgatgcaa gaatgagtgt caaaacggtc agtttattag gtattttgtc tacacttctt
    12361 acaggattat taacaggatt tgtagtattt atatgttcat tggcaggaaa tgcgcttgct
    12421 ggtgattttg gatggaaaac gtttgaacaa ccaatagttc agattttcta tggaatagga
    12481 gcagggctca ttagtttagg agtgacttct ctgctgttta acttattgga gaaaaagcat
    12541 tatttacgaa tttcacctga gctttctaac cgaactgtct tcctatcagg ttttaccttt
    12601 aggcaaggat tgaatatgag catacaaagt tcaattggag aagaggttat ctatcggcta
    12661 ttaatgattc cagtcatttg gtggatgagt ggaaatatcc tcatctccat tattgtatct
    12721 tcctttttat gggcggtgat gcaccaagta actggatatg acccaaggtg gatacgttgg
    12781 ctgcatctat ttatattcgg ttgctttctg ggagttctct tcatcaaatt tggttttatt
    12841 tgtgtattag tagctcattt cattcataat ttagtactcg tctgtatgcc gctgtggcag
    12901 ttcaagcttc agaaacatat gcatcatgat cagccaaagc atacttcact ctaatgatta
    12961 ggagaagatt tgatgcaatt gatgcaagtg caaaatttaa gcaaatacta tcgaaatggt
    13021 gatggggtcg aacatttgtc tttctcaatt caacgaggag aaatcgtggc gctattgggg
    13081 ccaaatggag ctgggaaaac aacgacaatt cggtgtttga caggtctcta taagccggat
    13141 aaaggagata tcctcattga gggttctcct ccgggacata taaatgttca aaaaaaagtc
    13201 gcgcttattc ctgatcagcc atatctgtat cccgctttaa ccgctgctga acatattcag
    13261 tttagggcaa gaggatatca tccaggtaaa aaagatgtaa aagaaagggt ttatcatgca
    13321 ttgaaggaag tgcacttgga ggagaaagca aaccaattgt gtggtcagct gtcaagaggc
    13381 caaaagcagc gggttgtcct ggcgggggcg attgttcaag acgctttgct gtatatatta
    13441 gacgaaccga ctgtgggcct tgatatccca tcaaaacagt ggctctctaa ctggttaaaa
    13501 actaaaaccg atcaagggtg ttcagcattt gtatcaactc atagtctaga gtttgttata
    13561 gagacagcag acagggtgat attaattaga gacggcaaac tcatgcagga tttgtatgtt
    13621 cctcaattcg aagaagaaca agcggaatgg agaaaagaag tgattcgtct tctaggggaa
    13681 tggtcagatg aataatatca tttctttttt atggcttcag tcaaaaaggc gttttgtcag
    13741 tcaaggtcag gaaaaaaaaa tgcctttttt gatcatgctc ctttttgttg gggccatcgg
    13801 atttcaagta agttttgttt ctagatctac gacatgggat atgagtattg ctggttgggt
    13861 acttacaggt gtttttatcc tttatacggc atttggactt ttttcaaatc gattaccaag
    13921 tcaaatggca gatattatat ggctttatgg cactgccaca tctttttcaa aagttgtgta
    13981 tagtgtttta tttttcagcg tcacttggaa ggcgttgctt tggatcatct cagccatatt
    14041 cggtgatgta ttaattgtgc ttctgtctgg tgatcataac aatttattag gccgatccat
    14101 aatttttgta gggctctttt ttgtcgctga agtgtggttg atgtcggtct cttgtgccag
    14161 aacagtgaag aaaatgaaaa gggtatacgt tttagtcttt cttctaatgt taggcattta
    14221 ctccatatgt ctttatcaat tcttctttct ccaacattca tctgggatat gggagagcat
    14281 tgcccgtttt attagtggcg ttggattagt gtttgataca ttgtcaccgt tgtatgtggt
    14341 tgtatttatt gggatcatca cagtctcttt tatgacaatt gctttttcga gccgtcaggt
    14401 agaaatgaag gaatcgttgg tgaaagaagc tgaattctgg gaggaatttc aagaacgtca
    14461 atttggttca ggtcaaatta tacagaaacc aaaaacgact tggtggggct tgcaaggtct
    14521 aaatggcatt tggtcttttc tgtggttgga actgttgctt tttaaaaaat atttattttt
    14581 tcatagcatt catacggtca tgctcagtgg cgtcttttat gtcgtcattt tcatgtatcc
    14641 agaatggttt tatcttcttt tctttcttat cgtctcggca gtcatgttaa gttcctatta
    14701 ttcaggaatt gtcagacatt ctcaatcagg cacccttcat ttattccccg gtgccctttg
    14761 gaaaaaaatc attattctag agctgacgaa tacagtctgg ttgtatattc tttactgtgt
    14821 ctctattact tttatggcag ttgggaattt agtttattgg tatatatatg gcttagggat
    14881 atatatatgg ttcatgacaa taaggctttt tgcttttacc catacaaacc gaaacgatat
    14941 taagctttca ttgcctcaat actacaagtc attttttatg gcattaggcc tgagcggcat
    15001 ttgtttgtat gtcattcatt tattgactgc tgactggtat acattagtgg tggtcgtctg
    15061 tatagggagc ctaagttggt gcctgtttta tcgtttcaga tagtggttat gtagagttat
    15121 tgttttaaaa cgaggagagg ggctctttta tgaattcaaa tggggataaa ttgtcgttat
    15181 ctgttcagaa tttagcgaat acaaatgaga tcacaattgt tcaagcgata ggtgagctaa
    15241 agaaatcggg aaaagatgca ataccagttt tggttgaggc cttaaaagag gaaggctctt
    15301 tgtgtaatat tgctgcagct gttttaggtg agtttgggga agacgcgagt gaagcagcgg
    15361 aggagctatc atgtttatta aaaagtcatg cggaagatac aagaatggca gcggcgattt
    15421 cattaatgag aatcgggaag cccagtctgc cctttgtcat caaaatcgct caagaaagtg
    15481 aagggcaatc gtgcttttgg gcatcttggt gtattgcatg gattgatccg tcttgcattg
    15541 aacctaagat gtataaatgt ctaaaatacg agcatgaaca tccttcagga atagttgctc
    15601 cgtttgcggc tgaagaggca ttaggaaagc tgattgcttt tcagctgaaa gataaggagg
    15661 actgaaagga tgaaagatga acaaatgttg actgaatggc caagtcattt accatggttg
    15721 aatcaatcac agaatgattt tacatttcca agtgacacat atcttcttct ttatttttgg
    15781 tcaatgagct gtccaaactg tcaccaatta acagacaaag tccttcaaga tataaaggat
    15841 atgaatgtga aagtaatcgg agtacatgtc ccctatatag aagaagagaa atctatggag
    15901 gttgtcttga cgtatgctct tgatagggga ctagctattc cgattgtatt agaccaaaac
    15961 tatgagatcg tcacaacttg tcacgtacaa ggcatcccca gcttttgtct attaagtcaa
    16021 tacggtcaga tcattactaa aacgatggga gatgttggtt gggataagat gttaaaaaag
    16081 attgcaggct tgtgaaattt tccgtcttgt atgtgcgaca aacggttgaa tattatgatg
    16141 aaacggtcct tcctataagc aggaaggttt tttaatgaaa tattttttta ttagtaggta
    16201 aattcatcaa atgttctgct atgctccaaa tgtacacctt tccgtaaggg caaagtcaaa
    16261 tgtgaaaaaa aactgttcca aagttaatca gaaatttatt ttcatattgt atcctttcgg
    16321 tatcaagtga aaggagcatc atatgaaaac attatggaaa gtcctcaaaa ttgtttttgt
    16381 cagcttggct gctttggttt tgcttgtatc cgtctcggta tttatttatc accatttcca
    16441 gctaaataag gaggcggcac tgctgaaagg taaaggcaca gtagtcgatg ttgacggtaa
    16501 aaagatgaat gtgtatcaag agggaagcgg gaaggatacg tttgtgttta tgtccggttc
    16561 ggggattgct gcgcctgctt atgaaatgaa ggggctgtac agcaagtttt caaaagaaaa
    16621 taagattgct gttgtagatc gggcaggtta tggatacagt gaagtgtctc acgatgacag
    16681 agatattgat acggtattgg aacagacgag gaaagcgctt atgaaaagcg gaaataagcc
    16741 tccttatatt ttaatgcctc attcgatatc cgggattgaa gcgatgtatt gggcacagaa
    16801 atatcctaag gaaatcaagg ccattattgc gatggatatt ggattgcccc agcagtacgt
    16861 cacgtataaa ttgagcggag ttgaccgatt gaaagtgaga gggttccacc tgttaacctc
    16921 gattggtttt catcggttta taccttccgc tgtatataat cctgaggtga ttcgacagtc
    16981 gtttttaact gatgaagaaa aagaaatcta taaagccatt aactttaagc aattttttaa
    17041 tgcagatatg gagcatgagc ttttacagtc ttaccaaaac ggcagcaaat ctgtgaatct
    17101 gcctgcgcca aaggaaactc ccgtcttgat tttagatgca gtctctgacc aaaatagaca
    17161 ttcaaagtat gctatacaaa accgaaaaga ctatgaagcg tttgcggctc aattcaatac
    17221 tgccgatata aaggaactga ggggaacaca cagtatttat ttatatcagc ctgatcaaat
    17281 atataaactg tccatggagt ttatgagaaa ggttcgctag gatgaagggt tatcgtattt
    17341 taatcgttga ggacgatgtg atgattggtg atttgctgca aaagattttg cagcgcgagg
    17401 gatatcgtgt gatatggaaa acagatggag cggatgtgct ttcggtgatt cagaaggtgg
    17461 atttggtcat tatggatgtg atgctgccgg gtgaagacgg gtatcaaatg tctgcaaaaa
    17521 tcaaaaagct ggggctgggc attccggtta tttttctctc agcccgcaat gacatggaca
    17581 gcaagcttca aggtttgcag atcggcgagg attatatggt aaagcccttt gatccgagag
    17641 agctgctatt aagaatgcgg aatatgcttg agcatcatta tgggaccttt acgcaaatca
    17701 aacatttgta tattgatgcg gtaacgaaaa aagtgttcaa tgaaagcctg catgatgagg
    17761 tattatttac tgcgattgag cggaaaattt tcttttattt atatgaaaat agagacagta
    17821 tcctgacaaa ggaacatttc tttgaatatc tatggcagct cgaagataga aacccgaata
    17881 ttgtcaatgt gcatattaaa aaaattagag ctaaaatcaa tgatcaagcg ggtgagatga
    17941 ttgaaaatat atatggagaa gggtatcggc tgaataccgt tgtgaagaaa tgaagctcaa
    18001 gacaaaatat cagttgttat tgtttacggc cgtcattagt gttccgatgc tattgctggc
    18061 ggtcagtgtt ttgatgtcgg tgatttatga cagcatgttt aaaccgatga atcatggtat
    18121 gccctttcac aggtcgtttg catacccggc aatgatcgtt gtatttttga tatcactctt
    18181 attgttagct tttttatttt caaagtcgat tcattctctg ttgcataaaa tcaatctatt
    18241 aaatcaaacc attcggcatt tggcgagtga tcaaagggtg cccgataaaa ttgaagtgaa
    18301 gcgtgctgat gaaatcgggg aactgatcaa gtcggtcaat ttgttaattg aacggacgac
    18361 atatcgtgaa ctggagctga gacagcagga ggaaatcaaa aaggagcttt tgcaaaaact
    18421 gcggcatgac attaatacac ctttaacggc tctcaggctg cagttatttt atttggaaga
    18481 ccaatgtcat ggtcaggctg tattcgaatc attgtatcag caaatcgaat atatctcgga
    18541 attaactaat gaattcaatc tatattccgc tgagacgctg gaaagctctt atattgtaaa
    18601 tgaagaagtg cgtctaaacg agctattaga aacagcggtg aaaaagtggg attatttata
    18661 cagtatgagt gggattgagc tgcactataa gccggcagat caagatgtga tatggatgag
    18721 caacacgtta tggatggaaa ggctgtttga taatattttt caaaatacgt taaggcattc
    18781 aaaagctaaa aagatggaag tcacgattga acatggcgat gtttttattc gtgatgacgg
    18841 tattggattt gatcggaatg agagcagtga gggacttggg ttaaagatta ttgaggatac
    18901 atgcaggctg cttgcgatta cttatgagct gcatacaaat gataacggaa cggggttctt
    18961 gttttcaaaa gagtgacccc gctgatgttt ttctttctcc tataaaattt atataatagg
    19021 gagaaagaaa tggggtgaac atcatatgtt taaaaaaatc atcaaaacga ttaagtacct
    19081 ctcaagcagt tctagtgacc gatatcgcag acaccggcat tacagcagca gccggcgcag
    19141 acattatcgc agctacagca gcagttcggg caaaagaaga cactacgacc gttatggcgg
    19201 cagtcatcgt tacaaacgcc ggagctacag cagcagttaa tccaaaaaaa gttcttgttc
    19261 cgcttttggg acaagggttt ttttatgtga ccgattgaat ggcccggttt agatcctcgc
    19321 gaatggaagc ggtgtgctga tactcttcct caatgcccaa taatcttttc agcagcaagg
    19381 ttacttcctt tgtcagtgtt aattcctcca gccaagtgcc gtttttcttc ttttttcctt
    19441 tatattgaga gtacagaaag aataacagcg tttctccgag atcgaagaag tcatcctgtt
    19501 ttcgtacctt tatttcctcc atttcttcag gagtcaattg tttggcaagg ccgaaatcga
    19561 tgaggcagag cctgccatca ttgatgatga tattaggcgt tctgatgtcg ctgtggaaga
    19621 taaggcgatc atgcaggtat tctataatct caagcagctg cgaaatcagt tgtaacgcca
    19681 taagctctgt gaacggctgt tttcgaaaaa ataataattc ttctatattc tctccctcaa
    19741 tgaactgcat gacataataa gcctgtccgt ctatgatgaa ttcatctatg aagcccggaa
    19801 tttgcgggtg gtgaatgttt ttgagcagtt ttatttcctg ctggaatcgg actttctctt
    19861 tttccttttt ggcttttgtc ggccgaagct gttttaagac ataaggtgtt tgagctagga
    19921 tatcggtgca caaataaacc aaaccgtagc ctcccatacc gaggcactct tcgattttgt
    19981 attgatgatt taagataacg ccgttcttta gagggcggtc aaatagcagt ttttttagaa
    20041 gttttaatgc catgtctgca cttcccttgg ttgtactgac tatagtttac cttctagacg
    20101 gagaataaaa aagagccgga taaccggctc ggtataagtt aaaactgctt tgtcacgtcg
    20161 tattcataat ctatttttgc ttttacgttg ctcatcgtcg atctggctgt cgctaatgta
    20221 ttatatttaa aactccatac ctttgccaca ctgagttgat ccgacaaaga gatatcataa
    20281 gaccctgaag tcgagctgtt tacaagggca cggctccatt cgttattttc gcttgtcatg
    20341 atcagatggc gtgtatttcc ctggcttggt gtttgagtgg cggttgtttg aactctggtt
    20401 acaatggcat cacgcggtat cccagattgg tttgttaaat caaccttgat cacgctggag
    20461 tcagaacctg aggggctaag gcttgtattt cctttatttt cagcaacgcc gctgaattgg
    20521 aacgttccgc tgcctgattt gattcggtct tcaattgaaa gcgtaaagta catgtttcca
    20581 gtataggtgc ctcgtgacac tttcacatag aaggtatccg tcgtgttttg ggcgtctgca
    20641 tttgcataaa taaaagaaga aaacgtatta gggttaataa cttctgtccc ttgagaaaca
    20701 ggtattctgt tcttgtcata aatttcaatt ttcatccctg tatacgcgct ctggtatgta
    20761 ctcctcatgt atactttttc tcccttatta gccgtaaaag tgaaataggc ttcatcttga
    20821 ccagcttcca gtattgttgt atcgatattt ttatttttcc aataaccgat cggcattgcg
    20881 gtatcaaatg aattgtttcc tgtgatagca gtgactccga cagctgatgc cgaatacgta
    20941 aaggtagata agacagaaag cataacagcg aattgaataa gccatttttt caccatgcaa
    21001 acaacctcct tttatttcca tcatacataa taacgattta ggtgtaaata aatgtttttt
    21061 gaggttaata tatacattat attcgccgat aaaaaagaat aagagagaat actcgggagg
    21121 gaattcaatg cgtctgaatc ggcaatttat ccgcactcag ctgattgcac agaacatatt
    21181 gagcaagaat gcgcctgcca aacgggagaa tgcgactgaa aatccagcgg cagttctgga
    21241 aaaggcatat agcaggctta agtcacaatc ttcaactggg ggaatcaatc agttcaatta
    21301 ttctaaaacc agcgtgtcgg gaaacagcgg gacgttcagc aaagtgtatc aatcagcgaa
    21361 tgatcgaaca gtgacagaca caggggaaga aacagtgatt caatcccaaa acccctatga
    21421 atctgagagt gatatcagaa tcaaaatact agatgaaaaa tacagcagga tgaatgcgat
    21481 taataaaaca aagtctgatc cattaggcta tattaaggat aagtaccaaa attcaaagtc
    21541 tccttatttc agaagtgatc tgtcagctgc agaaagacag gccgcttacg ataatgaaac
    21601 agaatggtta ttcaaaggga aggcgcaaaa ctataacctt caggatgctg tgtttcggaa
    21661 tgtcacattt catggggaag tggaagctga gaatgaaaag gtgtatcagc ggggacaggt
    21721 taaccagcag ctgcaagtac tgttgaatcg aaaccatatt catattccag aggggacaga
    21781 gctgacgttt acaatcacac cgattgacta tcaggtgcgg gtaagcggga cagacgatca
    21841 ggatctgatc aagcaaattg agcaagtgct gcaatctgga gacaacagca aagaactatt
    21901 tttacacatc atgaaaagtc aaagcagtga ttcagcacaa ttttccgaag aggcctatca
    21961 aaagtatcag gcagctcgtg agatgtatga agttacaggc taccatttga aggatttaga
    22021 agtgattgat gggcggtacg tcacgcctga gggacgtgac ttaatggatg tatataagga
    22081 agagcttgaa aaagatccag tgcagaaaca aacggcttct tatgctatat cttactatcg
    22141 ttcagagctc agtaaaatcg cggaagccgg gtataatgcc attccggatt tcatcctatc
    22201 aattgattac agcaatggat ctctgagaga tgtgggacaa agcaagagct atgggaccgg
    22261 agataccggg tggcttgaag cattaaagcg tcaaacgggt gtgaattatt aggtaagctg
    22321 ttcatgtagg acagcttatt ttttatgaga atctaagggg tgaattaatc ccaatattca
    22381 aataatttta ttatttttat ataaaagatt ttaaaagaag tgaacgattc aaaactctga
    22441 acaaaggtgt ttacctgaaa aaaacaattg tattttccag agaaatttat tatgatgaaa
    22501 taagtaattt aggagattat ataacaattt taagtttgaa ttttctgatt gttatcactg
    22561 attcatgtga aggcaagcag gtctgctgtt ttctcattta tgagtatttt gttaggagga
    22621 ggaagaggag tggcaaataa agaattaaag aggggcctgg gcgcgcgcca tattcagatg
    22681 atcgccttgg gcggtacaat cggtgttggc ttgtttatgg gttctgccag cacgatttca
    22741 tggactggcc catctgtcct tctggcttat gcaatatgcg gaatttttat cttttttatt
    22801 atgcgtgcga tgggtgaaat gctgtatgtc gagccgagca caggttcttt tgcgacgttc
    22861 ggccatcaat atattcatcc gatggcaggt tatataacag catggagcaa ctggttccag
    22921 tggattatcg tcggcatgtc agaaattatc gctg
//
